Local breeding of growing modes(LBGM)is a method used to generate initial condition perturbation(ICP)for convection-permitting ensemble forecasts.Equal weights(EWs)are usually presumed in LBGM during the localization ...Local breeding of growing modes(LBGM)is a method used to generate initial condition perturbation(ICP)for convection-permitting ensemble forecasts.Equal weights(EWs)are usually presumed in LBGM during the localization of ICP,without considering different contributions of the grid points within the local radius.To address this problem,Gaussian weights(GWs)are proposed in this study,which can accommodate the varied influences of the grids inside the local radius on the central grid through a Gaussian function.Specifically,two convection-permitting ensemble forecast experiments based on LBGM with GWs and EWs are compared and analyzed respectively for two squall line cases.The results showed that the use of the GWs intensified the local characteristics of the ICP and made the distribution of the ICP fields more flow-dependent.Kinetic energy spectrum of the ICP indicated that there could be more large-scale information in the ICP by using the GWs.In addition,mesoscale information also improved slightly.For forecast of nonprecipitation variables,GWs improved the relationship between the root-mean-square error and the spread and contributed to the forecasting accuracy of wind,temperature,geopotential height,and humidity.For the precipitation forecast,GWs simulated the precipitation structure successfully and provided better probability forecasting during the evolution of the two squall line processes than the EWs.展开更多
We propose a method based on the local breeding of growing modes(LBGM) considering strong local weather characteristics for convection-allowing ensemble forecasting. The impact radius was introduced in the breeding of...We propose a method based on the local breeding of growing modes(LBGM) considering strong local weather characteristics for convection-allowing ensemble forecasting. The impact radius was introduced in the breeding of growing modes to develop the LBGM method. In the local breeding process, the ratio between the root mean square error(RMSE) of local space forecast at each grid point and that of the initial full-field forecast is computed to rescale perturbations. Preliminary evaluations of the method based on a nature run were performed in terms of three aspects: perturbation structure, spread,and the RMSE of the forecast. The experimental results confirm that the local adaptability of perturbation schemes improves after rescaling by the LBGM method. For perturbation physical variables and some near-surface meteorological elements, the LBGM method could increase the spread and reduce the RMSE of forecast,improving the performance of the ensemble forecast system.In addition, different from those existing methods of global orthogonalization approach, this new initial-condition perturbation method takes into full consideration the local characteristics of the convective-scale weather system, thus making convectionallowing ensemble forecast more accurate.展开更多
Developing ecological scale breeding of local chickens with natural conditions, such as forest lands, grass lands, orchards and mulberry fields, not only can improve the quality of poultry products and the production ...Developing ecological scale breeding of local chickens with natural conditions, such as forest lands, grass lands, orchards and mulberry fields, not only can improve the quality of poultry products and the production benefits of chicken breeding, but also can develop and use local chicken germplasm effectively and promote their breed protection and industrialization. From integration and application of breed selection, breeding management, nutrient regulation, grass planting and grazing, a new ecological scale breeding technique of local chickens is proposed.展开更多
In recent decades, a considerable number of local breeds have been replaced by high-yielding breeds for reasons of profitability. Many local breeds are now threatened by extinction and the loss of their native genetic...In recent decades, a considerable number of local breeds have been replaced by high-yielding breeds for reasons of profitability. Many local breeds are now threatened by extinction and the loss of their native genetic diversity. The need to conserve breeds and their genetic diversity has a major importance due to the necessity for genetic change within and between populations. Novel approaches have to be explored and extended to maintain this genetic diversity. The aim of this study was the identification and implementation of breed-specific traits for a small, local sheep breed in northern Germany. The data comprised pedigree information, estimated breeding values (EBVs) of several conventional traits, and phenotypic information from a field experiment for two novel traits: 1) average daily gain under extensive circumstances (ADGE) and 2) ultrasonic measurements of muscle-fat ratio (UMFR). The experimental design included a dataset of 47 progeny from 14 pure-bred rams of German White-Headed Mutton (GWM). The methodical approach was divided into four parts: 1) the analysis of the breeding programme, 2) the identification of breed-specific traits, 3) the estimation and correlation of novel breeding values, and 4) the consequences of implementing these novel traits. Genetic parameters and correlations were conducted by applying linear mixed models. The estimates for the heritability (repeatability) were between 0.70 and 0.83 (0.42 and 0.46). The genetic correlation was positive (0.61) and in accordance with the phenotypic correlation (0.62). Average daily gain under intensive circumstances (ADGI) was moderately positive correlated with muscularity (0.60), as opposed to ADGE, which was moderately negative correlated with muscularity (-0.68). The EBV of ADGE was also moderately positive correlated with UMFR (0.64). Genetic response for ADGE enhanced to values of 481.09 g/day, 639.97 g/day, >700 g/day and >850 g/day for different selection intensity scenarios. Corresponding rates of inbreeding were 1.4%, 2.7%, 5.1%, and 7.9% after 10 years of selection. Genetic response for UMFR increased to 0.92, 1.34, 2.41, and >2.75, whereas remaining rates of inbreeding increased to 1.1%, 2.2%, 5.1%, and 7.9%. ADGI and ADGE were tendentially negatively correlated (-0.11), which strengthen the assumption of a biased ADGI. ADGE has a positive influence on meat-quality aspects (UMFR). Optimal use of reference sires with predefined selection intensity achieves genetic response for ADGE and UMFR with simultaneously acceptable rates of inbreeding.展开更多
The reproductive and lamb mortality data (n = 187) of the Local and crosses of Dorper × Local ewes following natural controlled breeding in Ethiopia were analysed. Data were collected during 2009-2011 at Sirinka ...The reproductive and lamb mortality data (n = 187) of the Local and crosses of Dorper × Local ewes following natural controlled breeding in Ethiopia were analysed. Data were collected during 2009-2011 at Sirinka breeding, evaluation and distribution site, eastern Amhara region of Ethiopia. Breed, lamb sex, birth season, birth year, birth type and ewes’ parity were considered as fixed effects. Data analyses were performed using general linear model procedures. Breed was a significant source of variation: the local sheep attained faster the age at first lambing than the crossbred ewe lambs (469 ± 8.45 vs. 555 ± 6.25 days, p < 0.0001), whereas the crossbred ewes weighed more than the local sheep ewes at the age of first lambing (32.7 ± 0.63 vs. 22.8 ± 0.43 kg, p < 0.0001). Birth year had also important influence on the age and weight at first lambing of ewes. Ewes showed better performance during the later study years, differences attributed due to the improved management advantages in later years. The crossbred and local ewes were comparable in their litter size, despite the fact that the lambing interval of crossbred ewes was longer than the local ewes (306 ± 4.62 vs. 287 ± 2.38 days). Additionally, there was no significant difference in mortality rate between the two breeds. This study confirms that the local ewes had higher annual reproductive rate than that of the crossbred sheep ewes (1.49 ± 0.02 vs. 1.37 ± 0.01 lambs) under the same environmental conditions. The present results suggested that better management and breeding program probably will increase the productivity of the local sheep.展开更多
Santomean pig farmer Simao Vicente was hopeful when he came to ask Zou Rui for help. His pig was suffering from hernia, and Zou, a 42-year-old Chinese agricultural expert working in Sao Tomé and Príncipe, wa...Santomean pig farmer Simao Vicente was hopeful when he came to ask Zou Rui for help. His pig was suffering from hernia, and Zou, a 42-year-old Chinese agricultural expert working in Sao Tomé and Príncipe, was the only person on the island who could provide emergency surgery.展开更多
Background Copy number variants(CNV)hold significant functional and evolutionary importance.Numerous ongoing CNV studies aim to elucidate the etiology of human diseases and gain insights into the population structure ...Background Copy number variants(CNV)hold significant functional and evolutionary importance.Numerous ongoing CNV studies aim to elucidate the etiology of human diseases and gain insights into the population structure of livestock.High-density chips have enabled the detection of CNV with increased resolution,leading to the identification of even small CNV.This study aimed to identify CNV in local Italian chicken breeds and investigate their distribution across the genome.Results Copy number variants were mainly distributed across the first six chromosomes and primarily associated with loss type CNV.The majority of CNV in the investigated breeds were of types 0 and 1,and the minimum length of CNV was significantly larger than that reported in previous studies.Interestingly,a high proportion of the length of chromosome 16 was covered by copy number variation regions(CNVR),with the major histocompatibility complex being the likely cause.Among the genes identified within CNVR,only those present in at least five animals across breeds(n=95)were discussed to reduce the focus on redundant CNV.Some of these genes have been associated to functional traits in chickens.Notably,several CNVR on different chromosomes harbor genes related to muscle development,tissue-specific biological processes,heat stress resistance,and immune response.Quantitative trait loci(QTL)were also analyzed to investigate potential overlapping with the identified CNVR:54 out of the 95 gene-containing regions overlapped with 428 QTL associated to body weight and size,carcass characteristics,egg production,egg components,fat deposition,and feed intake.Conclusions The genomic phenomena reported in this study that can cause changes in the distribution of CNV within the genome over time and the comparison of these differences in CNVR of the local chicken breeds could help in preserving these genetic resources.展开更多
The experiment was conducted at the animal experimental station of the Faculty of Animal Sciences,Royal University of Agriculture,commenced from 10 January to 14 March,2022.The CRD(Completely Randomized Design)was use...The experiment was conducted at the animal experimental station of the Faculty of Animal Sciences,Royal University of Agriculture,commenced from 10 January to 14 March,2022.The CRD(Completely Randomized Design)was used with 5 treatments and 4 replications.The 500 chicks at one-day-old,local bread,were purchased from farmers who run their small scale hatchery farm.The chicks were kept together till 21 days old,and then were allocated randomly into in five diets(treatments),25 chicks per replication.The feed formulas for this study were designed and calculated to maintain a protein content of approximately 17%,dividing into 5 feed formulas(Treatments),such as concentrated feed only(control treatment:T0),plus 10%of fresh sweet potato vine(T1),plus 20%of fresh sweet potato vine(T2),plus 30%of fresh sweet potato vine(T3)and plus 20%of sweet potato vine meal(T4).The results showed that the treatment T1,had a similar final weight with the treatment T4,but was slightly lower than the treatment T0 which used concentrated feed alone.Feed intake and FCR(Feed Conversion Ratio)were not significantly different among those treatments.In conclusion,the average daily weight gain of chickens seemed to decrease with increasing the level of fresh sweet potato vine.Thus,the optimum level of fresh sweet potato vine was 10%,which may have little effect on the growth performance of local chickens.In addition,it was not far different from the positive control treatment and the treatment using sweet potato vine meal.However,the producers can increase the amount of sweet potato vine in feed formula by processing it into meal and mixing with concentrated feed or using as feed ingredients.展开更多
[Objective] To observe differences in egg quality between Shandong local hens and Hyline brown hens. [Method] Hyline brown hens and three Shandong local chicken breeds including Jining Bairi chicken, Wenshang Luhua ch...[Objective] To observe differences in egg quality between Shandong local hens and Hyline brown hens. [Method] Hyline brown hens and three Shandong local chicken breeds including Jining Bairi chicken, Wenshang Luhua chicken and Laiwu black chicken were selected for egg quality comparison. [ Result] The pementage of yolk, egg-shape index and shell strength were significantly higher in the Shandong local hens than in Hyline brown hens ( P 〈 0.05), but the opposite results were found for average egg size and Haugh unit ( P 〈 0.05). The contents of essential amino acids and linoleic acid were significantly higher in the Shandong local hens than in Hyline brown hens (P 〈 0.05), but no significant differ- ence in VA content, VE content, total amino acid content and fatty acid content was found between the Shandong local hens than in Hyline brown hens. [ Conclustion] The study investigated the effects of chicken breeds on egg quality, which provides a reference for improvement of chicken breeds in future.展开更多
In this article, we reviewed the achievements of our team in genetic resource conservation and innovative use of Shandong local chicken breeds from the conservation, assessment on germplasm characteristics and breedin...In this article, we reviewed the achievements of our team in genetic resource conservation and innovative use of Shandong local chicken breeds from the conservation, assessment on germplasm characteristics and breeding of Shandong local chickens, so as to provide a reference for further research and development of local chicken breeds.展开更多
Local cattle breeds play a critical role in breeding programs due to their genetic adaptations to diverse environmental conditions.However,the genomic architecture of local cattle breeds in Kazakhstan remains largely ...Local cattle breeds play a critical role in breeding programs due to their genetic adaptations to diverse environmental conditions.However,the genomic architecture of local cattle breeds in Kazakhstan remains largely unexplored.This study utilized whole-genome sequencing data from Kazakh cattle to elucidate their genetic composition,uncovering three primary ancestral components:European,Eurasian,and East Asian taurine.The East Asian taurine lineage likely represents the earliest genetic contribution to Kazakh cattle but was largely replaced by subsequent waves of cattle migrations across Eurasia,leaving only a minor genetic signature in the current cattle population.In contrast,Eurasian taurine ancestry predominated in the Alatau and Kazakh local breeds,while the European taurine component was most prevalent in Kazakh white-headed cattle,consistent with their documented breeding history.Kazakh cattle exhibited higher genetic diversity and lower inbreeding coefficients compared to European commercial breeds,reflecting reduced exposure to intense artificial selection.A strong selection signal was identified on chromosome 6 at a locus encompassing PDGFRA,KIT,and KDR,which may be associated with the white-headed pigmentation characteristic of Kazakh white-headed cattle.Additional genes under selection were linked to lipid metabolism(IRS1,PRKG1,and ADCY8),meat production traits(KCNMA1,PDGFRA,HIF1A,and ANTXR1),and dairy production(ATP2B1,DHX15,FUK,NEGR1,CCDC91,COG4,and PTK2B).This study represents the first comprehensive analysis of nuclear genome data from local Kazakh cattle.It highlights the impact of historical cattle migrations across Eurasia on their genetic landscape and identifies key genomic regions under selection.These findings advance our understanding of the evolutionary history of cattle and offer valuable genetic resources for future breeding strategies.展开更多
基金Supported by the National Key Research and Development Program of China(2017YFC1501803)National Natural Science Foundation of China(41975128 and 41875060)。
文摘Local breeding of growing modes(LBGM)is a method used to generate initial condition perturbation(ICP)for convection-permitting ensemble forecasts.Equal weights(EWs)are usually presumed in LBGM during the localization of ICP,without considering different contributions of the grid points within the local radius.To address this problem,Gaussian weights(GWs)are proposed in this study,which can accommodate the varied influences of the grids inside the local radius on the central grid through a Gaussian function.Specifically,two convection-permitting ensemble forecast experiments based on LBGM with GWs and EWs are compared and analyzed respectively for two squall line cases.The results showed that the use of the GWs intensified the local characteristics of the ICP and made the distribution of the ICP fields more flow-dependent.Kinetic energy spectrum of the ICP indicated that there could be more large-scale information in the ICP by using the GWs.In addition,mesoscale information also improved slightly.For forecast of nonprecipitation variables,GWs improved the relationship between the root-mean-square error and the spread and contributed to the forecasting accuracy of wind,temperature,geopotential height,and humidity.For the precipitation forecast,GWs simulated the precipitation structure successfully and provided better probability forecasting during the evolution of the two squall line processes than the EWs.
基金supported by the Natural Science Foundation of Nanjing Joint Center of Atmospheric Research(Grant Nos.NJCAR2016MS02 and NJCAR2016ZD04)the National Natural Science Foundation of China(Grant Nos.41205073 and41675007)the National Key Research and Development Program of China(Grant No.2017YFC1501800)
文摘We propose a method based on the local breeding of growing modes(LBGM) considering strong local weather characteristics for convection-allowing ensemble forecasting. The impact radius was introduced in the breeding of growing modes to develop the LBGM method. In the local breeding process, the ratio between the root mean square error(RMSE) of local space forecast at each grid point and that of the initial full-field forecast is computed to rescale perturbations. Preliminary evaluations of the method based on a nature run were performed in terms of three aspects: perturbation structure, spread,and the RMSE of the forecast. The experimental results confirm that the local adaptability of perturbation schemes improves after rescaling by the LBGM method. For perturbation physical variables and some near-surface meteorological elements, the LBGM method could increase the spread and reduce the RMSE of forecast,improving the performance of the ensemble forecast system.In addition, different from those existing methods of global orthogonalization approach, this new initial-condition perturbation method takes into full consideration the local characteristics of the convective-scale weather system, thus making convectionallowing ensemble forecast more accurate.
基金Supported by Three New Agricultural Project in Jiangsu Province(SXGC[2013]234)
文摘Developing ecological scale breeding of local chickens with natural conditions, such as forest lands, grass lands, orchards and mulberry fields, not only can improve the quality of poultry products and the production benefits of chicken breeding, but also can develop and use local chicken germplasm effectively and promote their breed protection and industrialization. From integration and application of breed selection, breeding management, nutrient regulation, grass planting and grazing, a new ecological scale breeding technique of local chickens is proposed.
基金Financial support from the ministry of Energy,Agriculture,Environment,Nature,and Digitalization within the framework of the European Innovation Partnership(EIP Agri).
文摘In recent decades, a considerable number of local breeds have been replaced by high-yielding breeds for reasons of profitability. Many local breeds are now threatened by extinction and the loss of their native genetic diversity. The need to conserve breeds and their genetic diversity has a major importance due to the necessity for genetic change within and between populations. Novel approaches have to be explored and extended to maintain this genetic diversity. The aim of this study was the identification and implementation of breed-specific traits for a small, local sheep breed in northern Germany. The data comprised pedigree information, estimated breeding values (EBVs) of several conventional traits, and phenotypic information from a field experiment for two novel traits: 1) average daily gain under extensive circumstances (ADGE) and 2) ultrasonic measurements of muscle-fat ratio (UMFR). The experimental design included a dataset of 47 progeny from 14 pure-bred rams of German White-Headed Mutton (GWM). The methodical approach was divided into four parts: 1) the analysis of the breeding programme, 2) the identification of breed-specific traits, 3) the estimation and correlation of novel breeding values, and 4) the consequences of implementing these novel traits. Genetic parameters and correlations were conducted by applying linear mixed models. The estimates for the heritability (repeatability) were between 0.70 and 0.83 (0.42 and 0.46). The genetic correlation was positive (0.61) and in accordance with the phenotypic correlation (0.62). Average daily gain under intensive circumstances (ADGI) was moderately positive correlated with muscularity (0.60), as opposed to ADGE, which was moderately negative correlated with muscularity (-0.68). The EBV of ADGE was also moderately positive correlated with UMFR (0.64). Genetic response for ADGE enhanced to values of 481.09 g/day, 639.97 g/day, >700 g/day and >850 g/day for different selection intensity scenarios. Corresponding rates of inbreeding were 1.4%, 2.7%, 5.1%, and 7.9% after 10 years of selection. Genetic response for UMFR increased to 0.92, 1.34, 2.41, and >2.75, whereas remaining rates of inbreeding increased to 1.1%, 2.2%, 5.1%, and 7.9%. ADGI and ADGE were tendentially negatively correlated (-0.11), which strengthen the assumption of a biased ADGI. ADGE has a positive influence on meat-quality aspects (UMFR). Optimal use of reference sires with predefined selection intensity achieves genetic response for ADGE and UMFR with simultaneously acceptable rates of inbreeding.
文摘The reproductive and lamb mortality data (n = 187) of the Local and crosses of Dorper × Local ewes following natural controlled breeding in Ethiopia were analysed. Data were collected during 2009-2011 at Sirinka breeding, evaluation and distribution site, eastern Amhara region of Ethiopia. Breed, lamb sex, birth season, birth year, birth type and ewes’ parity were considered as fixed effects. Data analyses were performed using general linear model procedures. Breed was a significant source of variation: the local sheep attained faster the age at first lambing than the crossbred ewe lambs (469 ± 8.45 vs. 555 ± 6.25 days, p < 0.0001), whereas the crossbred ewes weighed more than the local sheep ewes at the age of first lambing (32.7 ± 0.63 vs. 22.8 ± 0.43 kg, p < 0.0001). Birth year had also important influence on the age and weight at first lambing of ewes. Ewes showed better performance during the later study years, differences attributed due to the improved management advantages in later years. The crossbred and local ewes were comparable in their litter size, despite the fact that the lambing interval of crossbred ewes was longer than the local ewes (306 ± 4.62 vs. 287 ± 2.38 days). Additionally, there was no significant difference in mortality rate between the two breeds. This study confirms that the local ewes had higher annual reproductive rate than that of the crossbred sheep ewes (1.49 ± 0.02 vs. 1.37 ± 0.01 lambs) under the same environmental conditions. The present results suggested that better management and breeding program probably will increase the productivity of the local sheep.
文摘Santomean pig farmer Simao Vicente was hopeful when he came to ask Zou Rui for help. His pig was suffering from hernia, and Zou, a 42-year-old Chinese agricultural expert working in Sao Tomé and Príncipe, was the only person on the island who could provide emergency surgery.
基金supported by the project“Protection of biodiversity of Italian poultry breeds—TuBAvI”,funded in the framework of the PSRN 2014–2020,submeasure 10.2“Support for sustainable conservation,use and development of genetic resources in agriculture”.
文摘Background Copy number variants(CNV)hold significant functional and evolutionary importance.Numerous ongoing CNV studies aim to elucidate the etiology of human diseases and gain insights into the population structure of livestock.High-density chips have enabled the detection of CNV with increased resolution,leading to the identification of even small CNV.This study aimed to identify CNV in local Italian chicken breeds and investigate their distribution across the genome.Results Copy number variants were mainly distributed across the first six chromosomes and primarily associated with loss type CNV.The majority of CNV in the investigated breeds were of types 0 and 1,and the minimum length of CNV was significantly larger than that reported in previous studies.Interestingly,a high proportion of the length of chromosome 16 was covered by copy number variation regions(CNVR),with the major histocompatibility complex being the likely cause.Among the genes identified within CNVR,only those present in at least five animals across breeds(n=95)were discussed to reduce the focus on redundant CNV.Some of these genes have been associated to functional traits in chickens.Notably,several CNVR on different chromosomes harbor genes related to muscle development,tissue-specific biological processes,heat stress resistance,and immune response.Quantitative trait loci(QTL)were also analyzed to investigate potential overlapping with the identified CNVR:54 out of the 95 gene-containing regions overlapped with 428 QTL associated to body weight and size,carcass characteristics,egg production,egg components,fat deposition,and feed intake.Conclusions The genomic phenomena reported in this study that can cause changes in the distribution of CNV within the genome over time and the comparison of these differences in CNVR of the local chicken breeds could help in preserving these genetic resources.
文摘The experiment was conducted at the animal experimental station of the Faculty of Animal Sciences,Royal University of Agriculture,commenced from 10 January to 14 March,2022.The CRD(Completely Randomized Design)was used with 5 treatments and 4 replications.The 500 chicks at one-day-old,local bread,were purchased from farmers who run their small scale hatchery farm.The chicks were kept together till 21 days old,and then were allocated randomly into in five diets(treatments),25 chicks per replication.The feed formulas for this study were designed and calculated to maintain a protein content of approximately 17%,dividing into 5 feed formulas(Treatments),such as concentrated feed only(control treatment:T0),plus 10%of fresh sweet potato vine(T1),plus 20%of fresh sweet potato vine(T2),plus 30%of fresh sweet potato vine(T3)and plus 20%of sweet potato vine meal(T4).The results showed that the treatment T1,had a similar final weight with the treatment T4,but was slightly lower than the treatment T0 which used concentrated feed alone.Feed intake and FCR(Feed Conversion Ratio)were not significantly different among those treatments.In conclusion,the average daily weight gain of chickens seemed to decrease with increasing the level of fresh sweet potato vine.Thus,the optimum level of fresh sweet potato vine was 10%,which may have little effect on the growth performance of local chickens.In addition,it was not far different from the positive control treatment and the treatment using sweet potato vine meal.However,the producers can increase the amount of sweet potato vine in feed formula by processing it into meal and mixing with concentrated feed or using as feed ingredients.
基金funded by the Agricultural Stock Breeding Project of Shandong Province (2008LZ015)
文摘[Objective] To observe differences in egg quality between Shandong local hens and Hyline brown hens. [Method] Hyline brown hens and three Shandong local chicken breeds including Jining Bairi chicken, Wenshang Luhua chicken and Laiwu black chicken were selected for egg quality comparison. [ Result] The pementage of yolk, egg-shape index and shell strength were significantly higher in the Shandong local hens than in Hyline brown hens ( P 〈 0.05), but the opposite results were found for average egg size and Haugh unit ( P 〈 0.05). The contents of essential amino acids and linoleic acid were significantly higher in the Shandong local hens than in Hyline brown hens (P 〈 0.05), but no significant differ- ence in VA content, VE content, total amino acid content and fatty acid content was found between the Shandong local hens than in Hyline brown hens. [ Conclustion] The study investigated the effects of chicken breeds on egg quality, which provides a reference for improvement of chicken breeds in future.
基金funded by the National High Technology Research and Development Program of China (2008AA101001)Major Agricultural Stock Breeding Project of Shandong Province(2007lz014)Earmarked Fund for Modern Agro-Industry Technology Research System
文摘In this article, we reviewed the achievements of our team in genetic resource conservation and innovative use of Shandong local chicken breeds from the conservation, assessment on germplasm characteristics and breeding of Shandong local chickens, so as to provide a reference for further research and development of local chicken breeds.
基金supported by the National Key R&D Program of China(2022YFF1000100)China Postdoctoral Science Foundation(2022M722615)。
文摘Local cattle breeds play a critical role in breeding programs due to their genetic adaptations to diverse environmental conditions.However,the genomic architecture of local cattle breeds in Kazakhstan remains largely unexplored.This study utilized whole-genome sequencing data from Kazakh cattle to elucidate their genetic composition,uncovering three primary ancestral components:European,Eurasian,and East Asian taurine.The East Asian taurine lineage likely represents the earliest genetic contribution to Kazakh cattle but was largely replaced by subsequent waves of cattle migrations across Eurasia,leaving only a minor genetic signature in the current cattle population.In contrast,Eurasian taurine ancestry predominated in the Alatau and Kazakh local breeds,while the European taurine component was most prevalent in Kazakh white-headed cattle,consistent with their documented breeding history.Kazakh cattle exhibited higher genetic diversity and lower inbreeding coefficients compared to European commercial breeds,reflecting reduced exposure to intense artificial selection.A strong selection signal was identified on chromosome 6 at a locus encompassing PDGFRA,KIT,and KDR,which may be associated with the white-headed pigmentation characteristic of Kazakh white-headed cattle.Additional genes under selection were linked to lipid metabolism(IRS1,PRKG1,and ADCY8),meat production traits(KCNMA1,PDGFRA,HIF1A,and ANTXR1),and dairy production(ATP2B1,DHX15,FUK,NEGR1,CCDC91,COG4,and PTK2B).This study represents the first comprehensive analysis of nuclear genome data from local Kazakh cattle.It highlights the impact of historical cattle migrations across Eurasia on their genetic landscape and identifies key genomic regions under selection.These findings advance our understanding of the evolutionary history of cattle and offer valuable genetic resources for future breeding strategies.