Implementing acoustic emission experiments with large rock samples, LURR (Load/Unload Response Ratio) theory was studied. The loading conditions in the experiments were designed to simulate the complicated loading pro...Implementing acoustic emission experiments with large rock samples, LURR (Load/Unload Response Ratio) theory was studied. The loading conditions in the experiments were designed to simulate the complicated loading process of underground rocks. The damages emerging inside the rock samples were recorded by the acoustic emission technique during the loading process. The experimental results were consistent with prediction by LURR theory. Integrating the changing processes of LURR value Y and the location process of acoustic emission events showed agreement between the variation of LURR value Y and the damage evolution inside the rocks. Furthermore, the high value of Y emerged before the complete breakdown of materials. Therefore, the damage evolution of rock specimen can be quantitatively analyzed with LURR theory, thus the failure of the rock materials and the earthquake occurrence may be predicted. The experimental results gave a further verification of LURR theory.展开更多
In this paper, the tempo-spatial evolution characteristics of the load/unload response ratio (namely LURR or Y value) before strong earthquakes with magnitude over 6 during 1976~1994 in California of America are studi...In this paper, the tempo-spatial evolution characteristics of the load/unload response ratio (namely LURR or Y value) before strong earthquakes with magnitude over 6 during 1976~1994 in California of America are studied in detail. The results show that there appear some high-Y regions cohering with the regional tectonic trend in a great area 3~4 years before strong earthquakes and these high-Y regions migrate from the periphery to the epicenter region at a speed of tens of kilometers per year. The load/unload response ratio (LURR) anomalies near the epicenter region characterizes a type of (ascend ? descend( and appear and increase steeply until one year or less before most earthquakes. (Positive( earthquakes form usually a concentration area; in and near which the main shock occurs. We have analyzed the different and same characters of earthquakes between California of American and the Chinese mainland. Basing on these results, we discuss the approach and method how to predict and estimate the three parameters (place, time and magnitude) of a strong earthquake in California of American by applying the characteristics of the LURR.展开更多
Rock experiment results indicate that the load/unload response ratio (LURR) of rocks expressed via strain energy may have singular or negative value after the stress in the rock reaches its maximum before rock failure...Rock experiment results indicate that the load/unload response ratio (LURR) of rocks expressed via strain energy may have singular or negative value after the stress in the rock reaches its maximum before rock failure or when the rock goes into the strain-weakening phase. The universality of this phenomenon is discussed. Expressed via strain or strain energy and the travel time of P wave, the variation form of the reciprocal of LURR during the process of rock failure preparation is derived. The results show that after a sharp decrease the reciprocal of LURR reaches its minimum when the main fracture of the rock is about to appear. This feature can be taken as an indication that the rock main fracture is impending.展开更多
The load/unload experiments on rock failure under pressure have been carried out in Material Test System (MTS) in the Laboratory for Non-linear Mechanics of Continuous Media (LNM), Institute of Mechanics, Chinese Acad...The load/unload experiments on rock failure under pressure have been carried out in Material Test System (MTS) in the Laboratory for Non-linear Mechanics of Continuous Media (LNM), Institute of Mechanics, Chinese Academy of Sciences, and load/unload response ratio (LURR) values with strain as response (i.e. inverse elastic constant as response rate) have been obtained. The experimental results are in accordance with theoretical results and those in real earthquakes: LURR rises just before rock failure. So LURR can be used as the precursor of rock failure and earthquake prediction.展开更多
The load/unload response ratio YQ with the geophysical parameter coda Q-1 of the crust as response is denned in this study.The variation in YQ-1 before and after the Northridge earthquake of January 17,1994(California...The load/unload response ratio YQ with the geophysical parameter coda Q-1 of the crust as response is denned in this study.The variation in YQ-1 before and after the Northridge earthquake of January 17,1994(California)has been investigated by using the data of coda Q-1 with frequencies of 1.5,3.0,6.0,12.0,and 24.0 Hz in the Southern California from 1987 to 1994.It can be found that YQ-1 for coda waves with all frequencies,the frequency of 12.0 Hz excluded,ascended to a certain extent prior to the occurrence of the rnainshock and returned to normality after the main shock.展开更多
The variation in load/unload response ratio before some moderate earthquakes is analyzed based on the theory of the load/unload response ratio.The results show that the load-unload response ratio increases noticeably ...The variation in load/unload response ratio before some moderate earthquakes is analyzed based on the theory of the load/unload response ratio.The results show that the load-unload response ratio increases noticeably before moderate earthquakes,and there are three kinds of patterns in which the load/unload response ratio varies and the duration of noticeable increase in load/unload response ratio ranges from half a year to two years.展开更多
In this paper, the theory of the load/unload response ratio is applied to the prediction of the reservoir-induced earthquakes, and variation of the load/unload response ratio Y preceding the occurrence of main shocks ...In this paper, the theory of the load/unload response ratio is applied to the prediction of the reservoir-induced earthquakes, and variation of the load/unload response ratio Y preceding the occurrence of main shocks of the reservoir-induced earthquakes in Xinfengjiang, Foziling, Danjiangkou, and Shenwo. The results show that the load/unload response ratio Y rises evidently prior to the main shocks.展开更多
The spatial temPOral evolution characteristics of the load/unload response ratio (Y) before strong earthquakes is studied in this paper. The results show that the regions of high value of Y migrate and converge to the...The spatial temPOral evolution characteristics of the load/unload response ratio (Y) before strong earthquakes is studied in this paper. The results show that the regions of high value of Y migrate and converge to the impending earthquake epicenter from different directions before the occurrence of the event. Basing on this discovery, it is proposed that the method can be used to predict the three elements of an earthquake. It was applied to predict that an earthquake would occur in the western part of Yunnan Province, southwestern China. The three elements (time, space and magnitude) of the Menglian earthquake with Ms7.3 which occurred on July 12, 1995 in Yunnan Province tallied with our prediction.展开更多
In this paper, through the nonlinear response of rock strain and stress, we have analized the physical mechanism of loading and unloading response ratio of the well level to the earth tides,the respouse of an aquife...In this paper, through the nonlinear response of rock strain and stress, we have analized the physical mechanism of loading and unloading response ratio of the well level to the earth tides,the respouse of an aquifer of confined well to bulk strain tide and showed two methods of the calculation of loading and unloading response ratio of the well level to the earth tides. We took the example of the Yu 01 well, which is near the epicenter of Heze M S 5.9 earthquake, calculated the response rate and loading and unloading response ratio of two kinds of the earth tides of it. The response rate and response ratio before the earthquake had the variation of increase.展开更多
This paper discussed the random distribution of the loading and unloading response ratio（LURR） of different definitions（Y<sub>1</sub>～Y<sub>5</sub>）using the assumptions that the earthquak...This paper discussed the random distribution of the loading and unloading response ratio（LURR） of different definitions（Y<sub>1</sub>～Y<sub>5</sub>）using the assumptions that the earthquakes occurfollowing the Poisson process and their magnitudes obey the Gutenberg-Richter law.Theresults show that Y<sub>1</sub>～Y<sub>5</sub> are quite stable or concentrated when the expected number of eventsin the calculation time window is relatively large（】40）;but when this occurrence ratebecomes very small,Y<sub>2</sub>～Y<sub>5</sub> become quite variable or unstable.That is to say,a high value ofthe LURR can be produced not only from seismicity before a large earthquake,but also from arandom sequence of earthquakes that obeys a Poisson process when the expected number ofevents in the window is too small.To check the influence of randomness in the catalogue tothe LURR,the random distribution of the LURR under Poisson models has been calculated bysimulation.90%,95% and 99% confidence ranges of Y<sub>1</sub> and Y<sub>3</sub> are given in this paper,which is helpful to quantify the random展开更多
In this paper,the Gutenberg-Richter model is used to generate seismic events.The events that satisfy the random distribution are also generated.With those events,the natural probability distribution of Load and Unload...In this paper,the Gutenberg-Richter model is used to generate seismic events.The events that satisfy the random distribution are also generated.With those events,the natural probability distribution of Load and Unload Response Ratio(LURR),which measures quantitatively the degree of instability of a nonlinear system,is discussed.The study is based on stress energy release,which is chosen as the response of nonlinear system F3.The comparative results from the observation catalogue and generating data are also studied.It is revealed that the natural probability of LURR is mostly stable when the sample number is sufficient.The lower the natural probability of LURR,the more the precursory is information it may contain.The influence of Y3 resulting from the sample number and the magnitude range of events is also discussed.展开更多
Many earthquakes occurred during the period 1994 -1996 in Sichuan and Yunnan Provinces, Southwest China. Taking the process of the initial main phase recovery phase of the magnetic storm as the process of load-unload ...Many earthquakes occurred during the period 1994 -1996 in Sichuan and Yunnan Provinces, Southwest China. Taking the process of the initial main phase recovery phase of the magnetic storm as the process of load-unload response of the geomagnetic field to the solar wind, we have estimated and analyzed the distribution in time and space of the load-unload response ratio P(z) of the storm time disturbance daily variation of the vertical component Z of the geomagnetic field at ten stations in Southwest China. We found that the area with high ratio P(z) was just the area where moderately strong earthquakes would occur from 44 days to 15 months later. The relationship between the high ratio P(z) and weather disasters in both seismic and non-seismic areas is discussed briefly.展开更多
The research progress of a novel traffic solution,a submerged floating tunnel（SFT）,is reviewed in terms of a study approach and loading scenario.Among existing publications,the buoyancy-weight ratio（BWR） is usuall...The research progress of a novel traffic solution,a submerged floating tunnel（SFT）,is reviewed in terms of a study approach and loading scenario.Among existing publications,the buoyancy-weight ratio（BWR） is usually predefined.However,BWR is a critical structural parameter that tremendously affects the dynamic behaviour of not only the tunnel tube itself but also the cable system.In the context of a SFT prototype（SFTP） project in Qiandao Lake（Zhejiang Province,China）,the importance of BWR is illustrated by finite element analysis and subsequently,an optimized BWR is proposed within a reasonable range in the present study.In the numerical model,structural damping is identified to be of importance.Rayleigh damping and the corresponding Rayleigh coefficients are attained through a sensitivity study,which shows that the adopted damping ratios are fairly suitable for SFTP.Lastly,the human sense of security is considered by quantifying the comfort index,which helps further optimize BWR in the SFTP structural parameter design.展开更多
Surrounding rocks at different locations are generally subjected to different stress paths during the process of deep hard rock excavation.In this study,to reveal the mechanical parameters of deep surrounding rock und...Surrounding rocks at different locations are generally subjected to different stress paths during the process of deep hard rock excavation.In this study,to reveal the mechanical parameters of deep surrounding rock under different stress paths,a new cyclic loading and unloading test method for controlled true triaxial loading and unloading and principal stress direction interchange was proposed,and the evolution of mechanical parameters of Shuangjiangkou granite under different stress paths was studied,including the deformation modulus,elastic deformation increment ratios,fracture degree,cohesion and internal friction angle.Additionally,stress path coefficient was defined to characterize different stress paths,and the functional relationships among the stress path coefficient,rock fracture degree difference coefficient,cohesion and internal friction angle were obtained.The results show that during the true triaxial cyclic loading and unloading process,the deformation modulus and cohesion gradually decrease,while the internal friction angle gradually increases with increasing equivalent crack strain.The stress path coefficient is exponentially related to the rock fracture degree difference coefficient.As the stress path coefficient increases,the degrees of cohesion weakening and internal friction angle strengthening decrease linearly.During cyclic loading and unloading under true triaxial principal stress direction interchange,the direction of crack development changes,and the deformation modulus increases,while the cohesion and internal friction angle decrease slightly,indicating that the principal stress direction interchange has a strengthening effect on the surrounding rocks.Finally,the influences of the principal stress interchange direction on the stabilities of deep engineering excavation projects are discussed.展开更多
AIM:To evaluate the aspartate aminotransferase(AST) to platelet ratio index(APRI) as a predictive factor of early viral response in chronic hepatitis C naive patients.METHODS:We performed an ambispective case-control ...AIM:To evaluate the aspartate aminotransferase(AST) to platelet ratio index(APRI) as a predictive factor of early viral response in chronic hepatitis C naive patients.METHODS:We performed an ambispective case-control study.We enrolled chronic hepatitis C naive patients who were evaluated to start therapy with PEGylated interferon α-2b(1.5 μg/kg per week) and ribavirin(>75 kg:1200mg and <75kg:1000mg).Patients were allocated into two groups,group 1:Hepatitis C patients with early viral response(EVR),group 2:Patients without EVR.Odds ratio(OR) and 95% confi dence interval(CI) were calculated to assess the relationship between each risk factor and the EVR in both groups.RESULTS:During the study,80 patients were analyzed,45 retrospectively and 35 prospectively.The mean ± SD age of our subjects was 42.9 ± 12 years;weight 70 kg(±11.19),AST 64.6 IU/mL(±48.74),alanine aminotransferase(ALT) 76.3 IU/mL(±63.08) and platelets 209000 mill/mm3(±84 429).Fifty-five(68.8%) were genotype 1 and 25(31.3%) were genotype 2 or 3;the mean hepatitis C virus RNA viral load was 2 269 061 IU/mL(±7220266).In the univariate analysis,APRI was not associated with EVR [OR 0.61(95% CI 0.229-1.655,P=0.33)],and the absence of EVR was only associated with genotype 1 [OR 0.28(95% CI 0.08-0.94,P=0.034)].After adjustment in a logistic regression model,genotype 1 remains signifi cant.CONCLUSION:APRI was not a predictor of EVR in chronic hepatitis C;Genotype 1 was the only predictive factor associated with the absence of EVR in our patients.展开更多
文摘Implementing acoustic emission experiments with large rock samples, LURR (Load/Unload Response Ratio) theory was studied. The loading conditions in the experiments were designed to simulate the complicated loading process of underground rocks. The damages emerging inside the rock samples were recorded by the acoustic emission technique during the loading process. The experimental results were consistent with prediction by LURR theory. Integrating the changing processes of LURR value Y and the location process of acoustic emission events showed agreement between the variation of LURR value Y and the damage evolution inside the rocks. Furthermore, the high value of Y emerged before the complete breakdown of materials. Therefore, the damage evolution of rock specimen can be quantitatively analyzed with LURR theory, thus the failure of the rock materials and the earthquake occurrence may be predicted. The experimental results gave a further verification of LURR theory.
基金State Natural Science Foundation (19732006) and Beijing Natural Science Foundation (8992008).
文摘In this paper, the tempo-spatial evolution characteristics of the load/unload response ratio (namely LURR or Y value) before strong earthquakes with magnitude over 6 during 1976~1994 in California of America are studied in detail. The results show that there appear some high-Y regions cohering with the regional tectonic trend in a great area 3~4 years before strong earthquakes and these high-Y regions migrate from the periphery to the epicenter region at a speed of tens of kilometers per year. The load/unload response ratio (LURR) anomalies near the epicenter region characterizes a type of (ascend ? descend( and appear and increase steeply until one year or less before most earthquakes. (Positive( earthquakes form usually a concentration area; in and near which the main shock occurs. We have analyzed the different and same characters of earthquakes between California of American and the Chinese mainland. Basing on these results, we discuss the approach and method how to predict and estimate the three parameters (place, time and magnitude) of a strong earthquake in California of American by applying the characteristics of the LURR.
基金Key project from China Seismological Bureau (9691309020301) State Natural Sciences Foundation of China (19732060).
文摘Rock experiment results indicate that the load/unload response ratio (LURR) of rocks expressed via strain energy may have singular or negative value after the stress in the rock reaches its maximum before rock failure or when the rock goes into the strain-weakening phase. The universality of this phenomenon is discussed. Expressed via strain or strain energy and the travel time of P wave, the variation form of the reciprocal of LURR during the process of rock failure preparation is derived. The results show that after a sharp decrease the reciprocal of LURR reaches its minimum when the main fracture of the rock is about to appear. This feature can be taken as an indication that the rock main fracture is impending.
基金This project was sponsored by the National Natural Science Foundation (No. 19732006), China and Ninth Five-year Plan, China Seismological Bureau.
文摘The load/unload experiments on rock failure under pressure have been carried out in Material Test System (MTS) in the Laboratory for Non-linear Mechanics of Continuous Media (LNM), Institute of Mechanics, Chinese Academy of Sciences, and load/unload response ratio (LURR) values with strain as response (i.e. inverse elastic constant as response rate) have been obtained. The experimental results are in accordance with theoretical results and those in real earthquakes: LURR rises just before rock failure. So LURR can be used as the precursor of rock failure and earthquake prediction.
基金This project was sponsored by the National Natural Science Foundation, China
文摘The load/unload response ratio YQ with the geophysical parameter coda Q-1 of the crust as response is denned in this study.The variation in YQ-1 before and after the Northridge earthquake of January 17,1994(California)has been investigated by using the data of coda Q-1 with frequencies of 1.5,3.0,6.0,12.0,and 24.0 Hz in the Southern California from 1987 to 1994.It can be found that YQ-1 for coda waves with all frequencies,the frequency of 12.0 Hz excluded,ascended to a certain extent prior to the occurrence of the rnainshock and returned to normality after the main shock.
文摘The variation in load/unload response ratio before some moderate earthquakes is analyzed based on the theory of the load/unload response ratio.The results show that the load-unload response ratio increases noticeably before moderate earthquakes,and there are three kinds of patterns in which the load/unload response ratio varies and the duration of noticeable increase in load/unload response ratio ranges from half a year to two years.
基金This project was sponsored by the Joint Earthquake Science Function and Natural Science Function, China.
文摘In this paper, the theory of the load/unload response ratio is applied to the prediction of the reservoir-induced earthquakes, and variation of the load/unload response ratio Y preceding the occurrence of main shocks of the reservoir-induced earthquakes in Xinfengjiang, Foziling, Danjiangkou, and Shenwo. The results show that the load/unload response ratio Y rises evidently prior to the main shocks.
文摘The spatial temPOral evolution characteristics of the load/unload response ratio (Y) before strong earthquakes is studied in this paper. The results show that the regions of high value of Y migrate and converge to the impending earthquake epicenter from different directions before the occurrence of the event. Basing on this discovery, it is proposed that the method can be used to predict the three elements of an earthquake. It was applied to predict that an earthquake would occur in the western part of Yunnan Province, southwestern China. The three elements (time, space and magnitude) of the Menglian earthquake with Ms7.3 which occurred on July 12, 1995 in Yunnan Province tallied with our prediction.
文摘In this paper, through the nonlinear response of rock strain and stress, we have analized the physical mechanism of loading and unloading response ratio of the well level to the earth tides,the respouse of an aquifer of confined well to bulk strain tide and showed two methods of the calculation of loading and unloading response ratio of the well level to the earth tides. We took the example of the Yu 01 well, which is near the epicenter of Heze M S 5.9 earthquake, calculated the response rate and loading and unloading response ratio of two kinds of the earth tides of it. The response rate and response ratio before the earthquake had the variation of increase.
基金This project was sponsored by the National Soience Foundation of China(19702060)
文摘This paper discussed the random distribution of the loading and unloading response ratio（LURR） of different definitions（Y<sub>1</sub>～Y<sub>5</sub>）using the assumptions that the earthquakes occurfollowing the Poisson process and their magnitudes obey the Gutenberg-Richter law.Theresults show that Y<sub>1</sub>～Y<sub>5</sub> are quite stable or concentrated when the expected number of eventsin the calculation time window is relatively large（】40）;but when this occurrence ratebecomes very small,Y<sub>2</sub>～Y<sub>5</sub> become quite variable or unstable.That is to say,a high value ofthe LURR can be produced not only from seismicity before a large earthquake,but also from arandom sequence of earthquakes that obeys a Poisson process when the expected number ofevents in the window is too small.To check the influence of randomness in the catalogue tothe LURR,the random distribution of the LURR under Poisson models has been calculated bysimulation.90%,95% and 99% confidence ranges of Y<sub>1</sub> and Y<sub>3</sub> are given in this paper,which is helpful to quantify the random
基金This project was sponsored by the State Seismological Bureau (85-04-05-04-05)
文摘In this paper,the Gutenberg-Richter model is used to generate seismic events.The events that satisfy the random distribution are also generated.With those events,the natural probability distribution of Load and Unload Response Ratio(LURR),which measures quantitatively the degree of instability of a nonlinear system,is discussed.The study is based on stress energy release,which is chosen as the response of nonlinear system F3.The comparative results from the observation catalogue and generating data are also studied.It is revealed that the natural probability of LURR is mostly stable when the sample number is sufficient.The lower the natural probability of LURR,the more the precursory is information it may contain.The influence of Y3 resulting from the sample number and the magnitude range of events is also discussed.
基金This project was sponsored by the China Seismlogical Bureau (No. 95-04-01, China.
文摘Many earthquakes occurred during the period 1994 -1996 in Sichuan and Yunnan Provinces, Southwest China. Taking the process of the initial main phase recovery phase of the magnetic storm as the process of load-unload response of the geomagnetic field to the solar wind, we have estimated and analyzed the distribution in time and space of the load-unload response ratio P(z) of the storm time disturbance daily variation of the vertical component Z of the geomagnetic field at ten stations in Southwest China. We found that the area with high ratio P(z) was just the area where moderately strong earthquakes would occur from 44 days to 15 months later. The relationship between the high ratio P(z) and weather disasters in both seismic and non-seismic areas is discussed briefly.
文摘The research progress of a novel traffic solution,a submerged floating tunnel（SFT）,is reviewed in terms of a study approach and loading scenario.Among existing publications,the buoyancy-weight ratio（BWR） is usually predefined.However,BWR is a critical structural parameter that tremendously affects the dynamic behaviour of not only the tunnel tube itself but also the cable system.In the context of a SFT prototype（SFTP） project in Qiandao Lake（Zhejiang Province,China）,the importance of BWR is illustrated by finite element analysis and subsequently,an optimized BWR is proposed within a reasonable range in the present study.In the numerical model,structural damping is identified to be of importance.Rayleigh damping and the corresponding Rayleigh coefficients are attained through a sensitivity study,which shows that the adopted damping ratios are fairly suitable for SFTP.Lastly,the human sense of security is considered by quantifying the comfort index,which helps further optimize BWR in the SFTP structural parameter design.
基金the financial support from the National Natural Science Foundation of China(Grant Nos.51839003 and 42207221).
文摘Surrounding rocks at different locations are generally subjected to different stress paths during the process of deep hard rock excavation.In this study,to reveal the mechanical parameters of deep surrounding rock under different stress paths,a new cyclic loading and unloading test method for controlled true triaxial loading and unloading and principal stress direction interchange was proposed,and the evolution of mechanical parameters of Shuangjiangkou granite under different stress paths was studied,including the deformation modulus,elastic deformation increment ratios,fracture degree,cohesion and internal friction angle.Additionally,stress path coefficient was defined to characterize different stress paths,and the functional relationships among the stress path coefficient,rock fracture degree difference coefficient,cohesion and internal friction angle were obtained.The results show that during the true triaxial cyclic loading and unloading process,the deformation modulus and cohesion gradually decrease,while the internal friction angle gradually increases with increasing equivalent crack strain.The stress path coefficient is exponentially related to the rock fracture degree difference coefficient.As the stress path coefficient increases,the degrees of cohesion weakening and internal friction angle strengthening decrease linearly.During cyclic loading and unloading under true triaxial principal stress direction interchange,the direction of crack development changes,and the deformation modulus increases,while the cohesion and internal friction angle decrease slightly,indicating that the principal stress direction interchange has a strengthening effect on the surrounding rocks.Finally,the influences of the principal stress interchange direction on the stabilities of deep engineering excavation projects are discussed.
文摘AIM:To evaluate the aspartate aminotransferase(AST) to platelet ratio index(APRI) as a predictive factor of early viral response in chronic hepatitis C naive patients.METHODS:We performed an ambispective case-control study.We enrolled chronic hepatitis C naive patients who were evaluated to start therapy with PEGylated interferon α-2b(1.5 μg/kg per week) and ribavirin(>75 kg:1200mg and <75kg:1000mg).Patients were allocated into two groups,group 1:Hepatitis C patients with early viral response(EVR),group 2:Patients without EVR.Odds ratio(OR) and 95% confi dence interval(CI) were calculated to assess the relationship between each risk factor and the EVR in both groups.RESULTS:During the study,80 patients were analyzed,45 retrospectively and 35 prospectively.The mean ± SD age of our subjects was 42.9 ± 12 years;weight 70 kg(±11.19),AST 64.6 IU/mL(±48.74),alanine aminotransferase(ALT) 76.3 IU/mL(±63.08) and platelets 209000 mill/mm3(±84 429).Fifty-five(68.8%) were genotype 1 and 25(31.3%) were genotype 2 or 3;the mean hepatitis C virus RNA viral load was 2 269 061 IU/mL(±7220266).In the univariate analysis,APRI was not associated with EVR [OR 0.61(95% CI 0.229-1.655,P=0.33)],and the absence of EVR was only associated with genotype 1 [OR 0.28(95% CI 0.08-0.94,P=0.034)].After adjustment in a logistic regression model,genotype 1 remains signifi cant.CONCLUSION:APRI was not a predictor of EVR in chronic hepatitis C;Genotype 1 was the only predictive factor associated with the absence of EVR in our patients.
