Intravascular large B-cell lymphoma(IVLBCL),a rare subtype of non-Hodgkin lymphoma,is classified as an independent subtype of extranodal diffuse large B-cell lymphoma(DLBCL)in the 2008 World Health Organization(WHO)Cl...Intravascular large B-cell lymphoma(IVLBCL),a rare subtype of non-Hodgkin lymphoma,is classified as an independent subtype of extranodal diffuse large B-cell lymphoma(DLBCL)in the 2008 World Health Organization(WHO)Classification(Turner et al.,2010).The 5th edition of the World Health Organization(WHO 2022)classification of hematolymphoid tumors retains this subtype(Alaggio et al.,2022).IVLBCL,which is characterized by neoplastic lymphocyte proliferation within the lumen of small blood vessels,tends to invade organs,such as the nervous system,skin,bone marrow(BM),and lung(D'Angelo et al.,2019;Satoh et al.,2019;Vasquez et al.,2019;Fukami et al.,2020).展开更多
Purpose:Service convenience explores how consumers perceive the time and effort associated with purchasing or using a service.It examines the impact of convenience on customer satisfaction,loyalty,and behavioral inten...Purpose:Service convenience explores how consumers perceive the time and effort associated with purchasing or using a service.It examines the impact of convenience on customer satisfaction,loyalty,and behavioral intentions,often considering various dimensions like access,search,and transaction convenience.The reviews also investigate how service convenience interacts with other factors like service quality,perceived value,and customer satisfaction.Therefore,this paper seeks to analyze the dispersed academic literature on service convenience research.This paper reviews the existing literature on service convenience and examines the directions in which the past studies have focused.It highlights the gap in existing literature to identify future research directions in service convenience domain.Through this review,this study aims to gain insights into various aspects including research methodology,framework,trends,important factors related to service convenience.Design/methodology/approach:Data were collected from an objective overview of service convenience research.This study used a systematic literature review approach.A total of 13 papers were published between 2012 and 2024.Selected from the Scopus database,and Emerald Insight,following specific criteria outlined in the PRISMA process.Findings:In the context of customer satisfaction research,analysis often reveals that satisfaction can be organized into several main themes.Here are five variables that frequently appear in on customer satisfaction,customer loyalty,behavioral intentions,often considering various dimensions like access,search,and transaction convenience.The analysis shows a significant spike in conveniencebased accounting research from 2012 to 2024,indicating growing interest in the topic.展开更多
With the promotion of the“Belt and Road Initiative”,Chinese sporting goods manufacturing enterprises are increasingly active in foreign investment in countries along the route,but due to regional differences,the inv...With the promotion of the“Belt and Road Initiative”,Chinese sporting goods manufacturing enterprises are increasingly active in foreign investment in countries along the route,but due to regional differences,the investment risks they face are becoming increasingly complex.Based on CNKI and Web of Science databases,this paper systematically combines the theoretical framework and research progress of sporting goods manufacturing enterprises’outbound investment and its risk research,and focuses on analyzing the evolution,motivation,characteristics,and risk generation mechanism of enterprises’outbound investment mode.It further discusses the types and causes of investment risks,the evolution and application of risk assessment methods,and deeply analyzes the unique risk characteristics of sports manufacturing enterprises.On this basis,combined with the shortcomings of existing research,a future research direction is put forward,which provides a reference for follow-up theoretical research and practical operation.展开更多
The integration of Learning Management Systems(LMSs)into educational settings is becoming increasingly common,especially in the digital field.Understanding the factors influencing the acceptance and effective use of L...The integration of Learning Management Systems(LMSs)into educational settings is becoming increasingly common,especially in the digital field.Understanding the factors influencing the acceptance and effective use of LMS is essential to ensure successful implementation.The Technology Acceptance Model(TAM)has been widely used to check user acceptance of various technologies,including LMS.This study conducted a systematic literature review(SLR)to analyze existing research on the application of TAM in the context of LMS.A comprehensive search of the academic database was conducted to identify relevant studies published in 2010-2025.The review synthesizes findings related to the core constructs of TAM—Perceived Usability,Perceived Ease of Use,Behavioral Intent,and Actual Use—as well as extended factors such as system quality,self-efficacy,and social influence.The results reveal circumstantial evidence supporting the predictive power of TAM in LMS adoption,while also highlighting emerging trends and gaps in the literature.This review contributes to a deeper understanding of user acceptance in a digital learning environment and provides recommendations for future research and practical LMS implementation strategies.展开更多
Background and Purpose: Therapeutic communication is a new term in family health care nursing, defined by Hohashi (2019) as a method of family intervention, and characterized by inclusion of not only verbal conversati...Background and Purpose: Therapeutic communication is a new term in family health care nursing, defined by Hohashi (2019) as a method of family intervention, and characterized by inclusion of not only verbal conversation but also nonverbal interaction. However, specific therapeutic communication methods have not been systematized. The purpose of this study was to clarify therapeutic communication methods for families/family members from the perspectives of verbal communication and non-verbal communication through a review of existing literature. Methods: We conducted a search using the medical literature databases PubMed and Ichushi-Web using the keywords “therapeutic communication”. Analysis was performed on seven articles from PubMed and 14 articles from Ichushi-Web that described therapeutic communication methods performed by healthcare professionals for families/family members. Through directed content analysis, therapeutic communication methods were subcategorized, and classified into three categories: verbal communication, non-verbal communication, and verbal/non-verbal communication. Results: A total of 23 subcategories were extracted. Verbal communication included 11 subcategories, such as “asking questions using the communicatee’s words as they are”. Non-verbal communication included five subcategories, such as “noticing changes in the content of the communicatee’s story”. And verbal/non-verbal communication featured seven subcategories, such as “making the communicatee aware of one’s own beliefs”. Conclusion: Therapeutic communication methods included basic care/caring in family interviews/meetings, as well as verbal communication and non-verbal communication that act on family/family members’ beliefs. It is believed that changes in family/family members’ beliefs can be used to eliminate, reduce, or improve problematic conditions in the family. .展开更多
The presented research illustrates the applicability and productiveness of the systematic literature review methodology, a non-empirical methodology in the geological sciences, particularly volcanology. The systematic...The presented research illustrates the applicability and productiveness of the systematic literature review methodology, a non-empirical methodology in the geological sciences, particularly volcanology. The systematic literature review methodology is a replicable, rigorous, and transparent methodology for synthesizing existing literature to answer questions on a specific topic. The synthesis allows for knowledge consolidation, such as identifying knowledge gaps. In our illustration of this methodology, we focused on the expanding knowledge about the magma pathway at Mount Cameroon, one of Africa’s active volcanoes. Our synthesis of the relevant international geoscience research literature is based on the framework of knowledge about the magma pathway beneath a typical basaltic volcano. The framework has three primary components: magma supply, storage, and transport to erupting vents. Across these components is a total of twelve secondary components. The result is a previously non-existent and fragmented overall understanding of the magma pathway at Mount Cameroon. The gaps in the understanding (such as in the magma supply rates, timescales of chamber processes, and magma ascent rates) may be addressed in future research. Another key implication of the presented research lies in the proof of concept of the systematic literature review methodology as an applicable qualitative research methodology in the study of volcanoes.展开更多
This paper provides a systematic literature review of text analysis methodologies used in blockchain-related research to comprehend and synthesize existing studies across disciplines and define future research directi...This paper provides a systematic literature review of text analysis methodologies used in blockchain-related research to comprehend and synthesize existing studies across disciplines and define future research directions.We summarize the research scope,text data,and methodologies of 124 papers and identify the two most common combinations of these dimensions:(1)papers that focus on specific cryptocurrencies tend to apply sentiment analysis to instant user-generated content or news articles to discover the correlations between public opinion and market behavior,and(2)studies that examine the broad concept of blockchain with text data from documents published by companies tend to apply topic modeling techniques to explore classifications and trends in blockchain development.We discover five major research topics in the academic literature:relationship discovery,cryptocurrency performance prediction,classification and trend,crime and regulation,and perception of blockchain.Based on these findings,we highlight three potential research directions for researchers to select topics and implement suitable methodologies for text analysis.展开更多
Objective:To identify the illustration of feeding patterns of stunting children using literature review method.Methods:This study was a descriptive narrative research using literature review approach to explore dietar...Objective:To identify the illustration of feeding patterns of stunting children using literature review method.Methods:This study was a descriptive narrative research using literature review approach to explore dietary habits of children with stunting problem.All the literature review processes employed Guideline Review measurement of Joanna Briggs Institute.Related ar ticles in literature were obtained from journal databases,such as Pub Med,Science Direct,Google Scholar,and Dimensions through structured research question with Patient,Exposure an interest,Outcome or response(PEO)methods.Results:This study found 2246 published ar ticles from 2018 to 2021 about children with stunting.Screening process was conducted fur ther to eliminate ar ticles with irrelevant titles and abstracts,and also the unsuitable ar ticles with the research question;hence,about 9 ar ticles were eligible to be reviewed ahead.All these ar ticles mentioned that children with irregular dietary habits would likely experience stunting.The low intake of nutritional food became the major predictor of stunting.Conclusions:Inappropriate feeding patterns and the variety of food were being the factors of stunting emergence among children<5 years of age.High consumption of carbohydrates,less animal-based protein,and misunderstanding about intake of sweetenedcondensed milk predisposed children to suffer stunting.展开更多
Waldenström macroglobulinemia is a rare lymphoid tumor accounting for 2% of all hematological malignancies. Renal complications are less common compared to multiple myeloma, with the most frequent renal manifesta...Waldenström macroglobulinemia is a rare lymphoid tumor accounting for 2% of all hematological malignancies. Renal complications are less common compared to multiple myeloma, with the most frequent renal manifestations being microproteinuria and microhematuria. This paper presents a case of Waldenström macroglobulinemia with acute kidney injury as the initial manifestation. A 75-year-old male was admitted to the Affiliated Hospital of Hebei University after elevated blood creatinine levels were detected for one day. Upon admission, his blood creatinine was 255 μmol/L, urine protein was 1+, urine erythrocytes were negative, electrophoresis showed IgM positivity in the κ-region, and a bone marrow biopsy indicated a tendency towards lymphoplasmacytic lymphoma. The patient was discharged after receiving a treatment regimen of prednisone acetate, thalidomide, and cyclophosphamide, and continued oral medication outside the hospital. The patient returned two weeks later due to diarrhea and was found to have a blood creatinine level of 985 μmol/L, along with severe acidosis and hyperkalemia. The patient refused renal replacement therapy and was not followed up, resulting in a poor prognosis. Additionally, a review of the literature is provided to contextualize this case within the broader scope of existing research.展开更多
Flipped classroom has been widely recognized as an innovative and effective instructional approach by educators and researchers.In the paper,the author did a series of researches on ESL flipped classroom teaching lite...Flipped classroom has been widely recognized as an innovative and effective instructional approach by educators and researchers.In the paper,the author did a series of researches on ESL flipped classroom teaching literature and made a related literature review on its application in college ESL teaching,aiming to explore more relevant effective strategies that can promote college ESL teaching and learning effect authentically.Besides,the review can also provide some research reference for college ESL educators.展开更多
We report a case of liver cell adenoma （LCA） in a 33-year-old female patient with special respect to its clonality status, pathogenic factors and differential diagnosis. The case was examined by histopathology, immu...We report a case of liver cell adenoma （LCA） in a 33-year-old female patient with special respect to its clonality status, pathogenic factors and differential diagnosis. The case was examined by histopathology, immunohistochemistry and a clonality assay based on X-chromosomal inactivation mosaicism in female somatic tissues and polymorphism at androgen receptor focus. The clinicopathological features of the reported cases from China and other countries were compared. The lesion was spherical, sizing 2 cm in its maximal dimension. Histologically, it was composed of cells arranged in cords, most of which were two-cell-thick and separated by sinusoids. Focal fatty change and excessive glycogen storage were observed. The tumor cells were round or polygonal in shape, resembling the surrounding parenchymal cells. Mitosis was not found. No portal tract, central vein or ductule was found within the lesion. The tumor tissue showed a positive reaction for cytokeratin （CK） 18, but not for CK19, vimentin, estrogen and progesterone receptors. Monoclonality was demonstrated for the lesion, confirming the diagnosis of an LCA. Clonality analysis is helpful for its distinction from focal nodular hyperplasia.K展开更多
To avoid credit fraud,social credit within an economic system has become an increasingly important criterion for the evaluation of economic agent activity and guaranteeing the development of a market economy with mini...To avoid credit fraud,social credit within an economic system has become an increasingly important criterion for the evaluation of economic agent activity and guaranteeing the development of a market economy with minimal supervision costs.This paper provides a comprehensive review of the social credit literature from the perspectives of theoretical foundation,scoring methods,and regulatory mechanisms.The study considers the credit of various economic agents within the social credit system such as countries(or governments),corporations,and individuals and their credit variations in online markets(i.e.,network credit).A historical review of the theoretical(or model)development of economic agents is presented together with significant works and future research directions.Some interesting conclusions are summarized from the literature review.(1)Credit theory studies can be categorized into traditional and emerging schools both focusing on the economic explanation of social credit in conjunction with creation and evolution mechanisms.(2)The most popular credit scoring methods include expert systems,econometric models,artificial intelligence(AI)techniques,and their hybrid forms.Evaluation indexes should vary across different target agents.(3)The most pressing task for regulatory mechanisms that supervise social credit to avoid credit fraud is the establishment of shared credit databases with consistent data standards.展开更多
This paper focuses on facilitating state-of-the-art applications of big data analytics(BDA) architectures and infrastructures to telecommunications(telecom) industrial sector.Telecom companies are dealing with terabyt...This paper focuses on facilitating state-of-the-art applications of big data analytics(BDA) architectures and infrastructures to telecommunications(telecom) industrial sector.Telecom companies are dealing with terabytes to petabytes of data on a daily basis. Io T applications in telecom are further contributing to this data deluge. Recent advances in BDA have exposed new opportunities to get actionable insights from telecom big data. These benefits and the fast-changing BDA technology landscape make it important to investigate existing BDA applications to telecom sector. For this, we initially determine published research on BDA applications to telecom through a systematic literature review through which we filter 38 articles and categorize them in frameworks, use cases, literature reviews, white papers and experimental validations. We also discuss the benefits and challenges mentioned in these articles. We find that experiments are all proof of concepts(POC) on a severely limited BDA technology stack(as compared to the available technology stack), i.e.,we did not find any work focusing on full-fledged BDA implementation in an operational telecom environment. To facilitate these applications at research-level, we propose a state-of-the-art lambda architecture for BDA pipeline implementation(called Lambda Tel) based completely on open source BDA technologies and the standard Python language, along with relevant guidelines.We discovered only one research paper which presented a relatively-limited lambda architecture using the proprietary AWS cloud infrastructure. We believe Lambda Tel presents a clear roadmap for telecom industry practitioners to implement and enhance BDA applications in their enterprises.展开更多
The advent of healthcare information management systems(HIMSs)continues to produce large volumes of healthcare data for patient care and compliance and regulatory requirements at a global scale.Analysis of this big da...The advent of healthcare information management systems(HIMSs)continues to produce large volumes of healthcare data for patient care and compliance and regulatory requirements at a global scale.Analysis of this big data allows for boundless potential outcomes for discovering knowledge.Big data analytics(BDA)in healthcare can,for instance,help determine causes of diseases,generate effective diagnoses,enhance Qo S guarantees by increasing efficiency of the healthcare delivery and effectiveness and viability of treatments,generate accurate predictions of readmissions,enhance clinical care,and pinpoint opportunities for cost savings.However,BDA implementations in any domain are generally complicated and resource-intensive with a high failure rate and no roadmap or success strategies to guide the practitioners.In this paper,we present a comprehensive roadmap to derive insights from BDA in the healthcare(patient care)domain,based on the results of a systematic literature review.We initially determine big data characteristics for healthcare and then review BDA applications to healthcare in academic research focusing particularly on No SQL databases.We also identify the limitations and challenges of these applications and justify the potential of No SQL databases to address these challenges and further enhance BDA healthcare research.We then propose and describe a state-of-the-art BDA architecture called Med-BDA for healthcare domain which solves all current BDA challenges and is based on the latest zeta big data paradigm.We also present success strategies to ensure the working of Med-BDA along with outlining the major benefits of BDA applications to healthcare.Finally,we compare our work with other related literature reviews across twelve hallmark features to justify the novelty and importance of our work.The aforementioned contributions of our work are collectively unique and clearly present a roadmap for clinical administrators,practitioners and professionals to successfully implement BDA initiatives in their organizations.展开更多
BACKGROUND The inflammatory myofibroblastic tumor(IMT)is a rare,idiopathic,usually benign,mass-forming disease with myofibroblastic proliferation and a varying amount of inflammatory cells.Although it can affect vario...BACKGROUND The inflammatory myofibroblastic tumor(IMT)is a rare,idiopathic,usually benign,mass-forming disease with myofibroblastic proliferation and a varying amount of inflammatory cells.Although it can affect various organs,the biliary tract is a rare localization of primary IMT,clinically,endoscopically and radiologically imitating cholangiocarcinoma.The treatment options are based only on clinical practice experience.CASE SUMMARY A 70-year-old woman was referred to our center due to progressive fatigue,weight loss,abdominal pain,night sweats,and elevated liver enzymes.Magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography(ERCP)revealed proximal common hepatic duct and hilar biliary strictures extending bilaterally to lobular bile ducts.Although initial clinical,endoscopic and radiological signs were typical for hilar cholangiocarcinoma,histological examination showed no signs of malignancy.In total,8 biopsies using different approaches were performed(several biopsies from dominant stricture during ERCP and direct cholangioscopy;ultrasound-guided liver biopsy;diagnostic laparoscopy with liver and lymph node biopsies).Histological examination revealed signs of IMT,and the final diagnosis of biliary IMT was stated.Although IMT is usually a benign disease,in our case,it was complicated.All pharmacological treatment measures were ineffective.The patient still needs permanent stenting,suffers from recurrent infections and mechanical jaundice.Despite that,the patient already survived 24 mo.CONCLUSION IMT presenting with hilar biliary strictures is a unique diagnostic and clinical challenge as it is indistinguishable from cholangiocarcinoma,and there are no evidence-based treatment options.Our goal is to increase the understanding of this rare disease and its possible course.展开更多
Biotechnology policies and regulations must be revised and updated to reflect the most recent advances in plantbreeding technology. New Plant Breeding Techniques(NPBT) such as gene editing have been applied to address...Biotechnology policies and regulations must be revised and updated to reflect the most recent advances in plantbreeding technology. New Plant Breeding Techniques(NPBT) such as gene editing have been applied to address the myriad of challenges in plant breeding, while the use of NPBT as emerging biotechnological tools raises legal and ethical concerns. This study aims to highlight how gene editing is operationalized in the existing literature and examine the critical issues of ethical and legal issues of gene editing for plant breeding. We carried out a systematic literature review(SLR) to provide the current states of ethical and legal discourses surrounding this topic. We also identified critical research priority areas and policy gaps that must be addressed when designing the future governance of gene editing in plant breeding.展开更多
BACKGROUND Lymphoepithelioma-like carcinoma(LELC),a rare and unique variant of liver cancer,can be divided into lymphoepithelioma-like hepatocellular carcinoma and lymphoepithelioma-like intrahepatic cholangiocarcinom...BACKGROUND Lymphoepithelioma-like carcinoma(LELC),a rare and unique variant of liver cancer,can be divided into lymphoepithelioma-like hepatocellular carcinoma and lymphoepithelioma-like intrahepatic cholangiocarcinoma.Dense lymphocytic infiltration is its characteristic pathological feature.In recent years,the number of reported cases of this type has increased each year.Studies have shown that lymphoepithelioma-like cholangiocarcinoma occurs more frequently in Asian women;LELC is associated with Epstein–Barr virus infection of liver cells of epithelial origin.Existing research shows that the prognosis of this tumour is good.CASE SUMMARY A 38-year-old female patient was hospitalized after 3 mo of abdominal pain and nausea.She had been infected with hepatitis B virus more than 10 years prior.The patient was hospitalized on January 21,2022.Magnetic resonance imaging showed a 36 mm×28 mm mass under the envelope of the left inner lobe of the liver.No metastasis of lymph nodes or other organs was observed.After left hemihepatectomy,biopsy and immunohistochemistry yielded a final diagnosis of lymphoepithelial hepatocellular carcinoma.After 12 mo of outpatient follow-up and chemotherapy,no tumour metastases were found on the latest computed tomography examination.CONCLUSION Herein,the patient was treated surgically and then followed up as an outpatient for 12 mo.This case will further expand our overall knowledge of the diagnosis and treatment of this rare tumor.展开更多
BACKGROUND Gastroenteropancreatic neuroendocrine tumours(GEP-NETs)are slow-growing cancers that arise from diffuse endocrine cells in the gastrointestinal tract(GINETs)or the pancreas(P-NETs).They are relatively uncom...BACKGROUND Gastroenteropancreatic neuroendocrine tumours(GEP-NETs)are slow-growing cancers that arise from diffuse endocrine cells in the gastrointestinal tract(GINETs)or the pancreas(P-NETs).They are relatively uncommon,accounting for 2%of all gastrointestinal malignancies.The usual treatment options in advanced GEP-NET patients with metastatic disease include chemotherapy,biological therapies,and peptide receptor radionuclide therapy.Understanding the impact of treatment on GEP-NET patients is paramount given the nature of the disease.Health-related quality of life(HRQoL)is increasingly important as a concept reflecting the patients’perspective in conjunction with the disease presentation,severity and treatment.AIM To conduct a systematic literature review to identify literature reporting HRQoL data in patients with GEP-NETs between January 1985 and November 2019.METHODS The PRISMA guiding principles were applied.MEDLINE,Embase and the Cochrane library were searched.Data extracted from the publications included type of study,patient population data(mid-gut/hind-gut/GI-NET/P-NET),sample size,intervention/comparators,HRQoL instruments,average and data spread of overall and sub-scores,and follow-up time for data collection.RESULTS Forty-three publications met the inclusion criteria.The heterogeneous nature of the different study populations was evident;the percentage of female participants ranged between 30%-60%,whilst average age ranged from 53.8 to 67.0 years.Eight studies investigated GI-NET patients only,six studies focused exclusively on P-NET patients and the remaining studies involved both patient populations or did not report the location of the primary tumour.The most commonly used instrument was the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-C30(n=28)with consistent results across studies;the GI-NET-specific module Quality of Life Questionnaire-GINET21 was used in six of these studies.A number of randomised trials demonstrated no HRQoL changes between active treatment and placebo arms.The Phase III NETTER-1 study provides the best data available for advanced GEP-NET patients;it shows that peptide receptor radionuclide therapy can significantly improve GEP-NET patients’HRQoL.CONCLUSION HRQoL instruments offer a means to monitor patients’general disease condition,disease progression and their physical and mental well-being.Instruments including the commonly used European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-C30 and GINET21 lack,however,validation and a defined minimal clinical important difference specifically for GINET and P-NET patients.展开更多
CLINICAL STUDIES Clinical studies on Chinese herbal medicine(CHM)in lung cancer(LC)have largely been on anumber of basic formulae selected by syndrome(Zheng)differentiation,or specific formula basedon clinical experie...CLINICAL STUDIES Clinical studies on Chinese herbal medicine(CHM)in lung cancer(LC)have largely been on anumber of basic formulae selected by syndrome(Zheng)differentiation,or specific formula basedon clinical experience.There have also been anumber of studies comparing combination ofCHMs with either chemotherapy or radiotherapywith chemotherapy or radiotherapy alone,to as-sess any additional benefits or synergistic outcomesof the combination.展开更多
BACKGROUND Isolated splenic metastasis is a rare clinical entity.Multiple metastases in the spleen after radical colon resection in a patient who subsequently underwent a second local resection for isolated metachrono...BACKGROUND Isolated splenic metastasis is a rare clinical entity.Multiple metastases in the spleen after radical colon resection in a patient who subsequently underwent a second local resection for isolated metachronous splenic metastasis are exceedingly rare.CASE SUMMARY We report a colon cancer patient who underwent laparoscopic radical colon resection 14 mo previously,and subsequently underwent a second local resection due to local recurrence detected by elevated serum carcinoembryonic antigen(CEA)and positron emission tomography(PET).However,multiple metastases in the spleen were found 7 mo later by elevated serum CEA and PET-magnetic resonance imaging.Then the patient underwent total laparoscopic splenectomy.Local tumor recurrence and splenic metastasis from colorectal cancer(CRC)were found by postoperative pathology.Genetic analysis of these recurrent and metastatic tissues showed KRAS exon2,APC exon16 and TP53 exon6 missense mutations,but no mutations of NRAS,KRAF,EGFR,ERBB2,MET,MLH1,MSH2 and MSH6 were detected.Chemotherapy and target therapy were administered after multiple disciplinary team(MDT)consultation,and no tumor recurrence has been observed to date.We also reviewed the literature by conducting a search of the PubMed database using the following key words:CRC,splenic metastasis,isolated,and review.We identified 34 relevant papers,which included 28 cases of metachronous metastasis and 6 cases of simultaneous metastasis.CONCLUSION Close monitoring of serum CEA levels is crucial for the detection of isolated splenic metastases after colon surgery.In terms of overall survival and progression-free survival,MDT plays an important role in the entire process of disease management.展开更多
文摘Intravascular large B-cell lymphoma(IVLBCL),a rare subtype of non-Hodgkin lymphoma,is classified as an independent subtype of extranodal diffuse large B-cell lymphoma(DLBCL)in the 2008 World Health Organization(WHO)Classification(Turner et al.,2010).The 5th edition of the World Health Organization(WHO 2022)classification of hematolymphoid tumors retains this subtype(Alaggio et al.,2022).IVLBCL,which is characterized by neoplastic lymphocyte proliferation within the lumen of small blood vessels,tends to invade organs,such as the nervous system,skin,bone marrow(BM),and lung(D'Angelo et al.,2019;Satoh et al.,2019;Vasquez et al.,2019;Fukami et al.,2020).
文摘Purpose:Service convenience explores how consumers perceive the time and effort associated with purchasing or using a service.It examines the impact of convenience on customer satisfaction,loyalty,and behavioral intentions,often considering various dimensions like access,search,and transaction convenience.The reviews also investigate how service convenience interacts with other factors like service quality,perceived value,and customer satisfaction.Therefore,this paper seeks to analyze the dispersed academic literature on service convenience research.This paper reviews the existing literature on service convenience and examines the directions in which the past studies have focused.It highlights the gap in existing literature to identify future research directions in service convenience domain.Through this review,this study aims to gain insights into various aspects including research methodology,framework,trends,important factors related to service convenience.Design/methodology/approach:Data were collected from an objective overview of service convenience research.This study used a systematic literature review approach.A total of 13 papers were published between 2012 and 2024.Selected from the Scopus database,and Emerald Insight,following specific criteria outlined in the PRISMA process.Findings:In the context of customer satisfaction research,analysis often reveals that satisfaction can be organized into several main themes.Here are five variables that frequently appear in on customer satisfaction,customer loyalty,behavioral intentions,often considering various dimensions like access,search,and transaction convenience.The analysis shows a significant spike in conveniencebased accounting research from 2012 to 2024,indicating growing interest in the topic.
文摘With the promotion of the“Belt and Road Initiative”,Chinese sporting goods manufacturing enterprises are increasingly active in foreign investment in countries along the route,but due to regional differences,the investment risks they face are becoming increasingly complex.Based on CNKI and Web of Science databases,this paper systematically combines the theoretical framework and research progress of sporting goods manufacturing enterprises’outbound investment and its risk research,and focuses on analyzing the evolution,motivation,characteristics,and risk generation mechanism of enterprises’outbound investment mode.It further discusses the types and causes of investment risks,the evolution and application of risk assessment methods,and deeply analyzes the unique risk characteristics of sports manufacturing enterprises.On this basis,combined with the shortcomings of existing research,a future research direction is put forward,which provides a reference for follow-up theoretical research and practical operation.
文摘The integration of Learning Management Systems(LMSs)into educational settings is becoming increasingly common,especially in the digital field.Understanding the factors influencing the acceptance and effective use of LMS is essential to ensure successful implementation.The Technology Acceptance Model(TAM)has been widely used to check user acceptance of various technologies,including LMS.This study conducted a systematic literature review(SLR)to analyze existing research on the application of TAM in the context of LMS.A comprehensive search of the academic database was conducted to identify relevant studies published in 2010-2025.The review synthesizes findings related to the core constructs of TAM—Perceived Usability,Perceived Ease of Use,Behavioral Intent,and Actual Use—as well as extended factors such as system quality,self-efficacy,and social influence.The results reveal circumstantial evidence supporting the predictive power of TAM in LMS adoption,while also highlighting emerging trends and gaps in the literature.This review contributes to a deeper understanding of user acceptance in a digital learning environment and provides recommendations for future research and practical LMS implementation strategies.
文摘Background and Purpose: Therapeutic communication is a new term in family health care nursing, defined by Hohashi (2019) as a method of family intervention, and characterized by inclusion of not only verbal conversation but also nonverbal interaction. However, specific therapeutic communication methods have not been systematized. The purpose of this study was to clarify therapeutic communication methods for families/family members from the perspectives of verbal communication and non-verbal communication through a review of existing literature. Methods: We conducted a search using the medical literature databases PubMed and Ichushi-Web using the keywords “therapeutic communication”. Analysis was performed on seven articles from PubMed and 14 articles from Ichushi-Web that described therapeutic communication methods performed by healthcare professionals for families/family members. Through directed content analysis, therapeutic communication methods were subcategorized, and classified into three categories: verbal communication, non-verbal communication, and verbal/non-verbal communication. Results: A total of 23 subcategories were extracted. Verbal communication included 11 subcategories, such as “asking questions using the communicatee’s words as they are”. Non-verbal communication included five subcategories, such as “noticing changes in the content of the communicatee’s story”. And verbal/non-verbal communication featured seven subcategories, such as “making the communicatee aware of one’s own beliefs”. Conclusion: Therapeutic communication methods included basic care/caring in family interviews/meetings, as well as verbal communication and non-verbal communication that act on family/family members’ beliefs. It is believed that changes in family/family members’ beliefs can be used to eliminate, reduce, or improve problematic conditions in the family. .
文摘The presented research illustrates the applicability and productiveness of the systematic literature review methodology, a non-empirical methodology in the geological sciences, particularly volcanology. The systematic literature review methodology is a replicable, rigorous, and transparent methodology for synthesizing existing literature to answer questions on a specific topic. The synthesis allows for knowledge consolidation, such as identifying knowledge gaps. In our illustration of this methodology, we focused on the expanding knowledge about the magma pathway at Mount Cameroon, one of Africa’s active volcanoes. Our synthesis of the relevant international geoscience research literature is based on the framework of knowledge about the magma pathway beneath a typical basaltic volcano. The framework has three primary components: magma supply, storage, and transport to erupting vents. Across these components is a total of twelve secondary components. The result is a previously non-existent and fragmented overall understanding of the magma pathway at Mount Cameroon. The gaps in the understanding (such as in the magma supply rates, timescales of chamber processes, and magma ascent rates) may be addressed in future research. Another key implication of the presented research lies in the proof of concept of the systematic literature review methodology as an applicable qualitative research methodology in the study of volcanoes.
基金supported by the Manchot Graduate School“Competitiveness of Young Enterprises”at the Heinrich-Heine-University of Düsseldorf.Funding was provided by the Jürgen Manchot Stiftung.
文摘This paper provides a systematic literature review of text analysis methodologies used in blockchain-related research to comprehend and synthesize existing studies across disciplines and define future research directions.We summarize the research scope,text data,and methodologies of 124 papers and identify the two most common combinations of these dimensions:(1)papers that focus on specific cryptocurrencies tend to apply sentiment analysis to instant user-generated content or news articles to discover the correlations between public opinion and market behavior,and(2)studies that examine the broad concept of blockchain with text data from documents published by companies tend to apply topic modeling techniques to explore classifications and trends in blockchain development.We discover five major research topics in the academic literature:relationship discovery,cryptocurrency performance prediction,classification and trend,crime and regulation,and perception of blockchain.Based on these findings,we highlight three potential research directions for researchers to select topics and implement suitable methodologies for text analysis.
文摘Objective:To identify the illustration of feeding patterns of stunting children using literature review method.Methods:This study was a descriptive narrative research using literature review approach to explore dietary habits of children with stunting problem.All the literature review processes employed Guideline Review measurement of Joanna Briggs Institute.Related ar ticles in literature were obtained from journal databases,such as Pub Med,Science Direct,Google Scholar,and Dimensions through structured research question with Patient,Exposure an interest,Outcome or response(PEO)methods.Results:This study found 2246 published ar ticles from 2018 to 2021 about children with stunting.Screening process was conducted fur ther to eliminate ar ticles with irrelevant titles and abstracts,and also the unsuitable ar ticles with the research question;hence,about 9 ar ticles were eligible to be reviewed ahead.All these ar ticles mentioned that children with irregular dietary habits would likely experience stunting.The low intake of nutritional food became the major predictor of stunting.Conclusions:Inappropriate feeding patterns and the variety of food were being the factors of stunting emergence among children<5 years of age.High consumption of carbohydrates,less animal-based protein,and misunderstanding about intake of sweetenedcondensed milk predisposed children to suffer stunting.
文摘Waldenström macroglobulinemia is a rare lymphoid tumor accounting for 2% of all hematological malignancies. Renal complications are less common compared to multiple myeloma, with the most frequent renal manifestations being microproteinuria and microhematuria. This paper presents a case of Waldenström macroglobulinemia with acute kidney injury as the initial manifestation. A 75-year-old male was admitted to the Affiliated Hospital of Hebei University after elevated blood creatinine levels were detected for one day. Upon admission, his blood creatinine was 255 μmol/L, urine protein was 1+, urine erythrocytes were negative, electrophoresis showed IgM positivity in the κ-region, and a bone marrow biopsy indicated a tendency towards lymphoplasmacytic lymphoma. The patient was discharged after receiving a treatment regimen of prednisone acetate, thalidomide, and cyclophosphamide, and continued oral medication outside the hospital. The patient returned two weeks later due to diarrhea and was found to have a blood creatinine level of 985 μmol/L, along with severe acidosis and hyperkalemia. The patient refused renal replacement therapy and was not followed up, resulting in a poor prognosis. Additionally, a review of the literature is provided to contextualize this case within the broader scope of existing research.
文摘Flipped classroom has been widely recognized as an innovative and effective instructional approach by educators and researchers.In the paper,the author did a series of researches on ESL flipped classroom teaching literature and made a related literature review on its application in college ESL teaching,aiming to explore more relevant effective strategies that can promote college ESL teaching and learning effect authentically.Besides,the review can also provide some research reference for college ESL educators.
基金Supported by the National Natural Science Foundation of China, No. 30171052 and No. 30572125
文摘We report a case of liver cell adenoma （LCA） in a 33-year-old female patient with special respect to its clonality status, pathogenic factors and differential diagnosis. The case was examined by histopathology, immunohistochemistry and a clonality assay based on X-chromosomal inactivation mosaicism in female somatic tissues and polymorphism at androgen receptor focus. The clinicopathological features of the reported cases from China and other countries were compared. The lesion was spherical, sizing 2 cm in its maximal dimension. Histologically, it was composed of cells arranged in cords, most of which were two-cell-thick and separated by sinusoids. Focal fatty change and excessive glycogen storage were observed. The tumor cells were round or polygonal in shape, resembling the surrounding parenchymal cells. Mitosis was not found. No portal tract, central vein or ductule was found within the lesion. The tumor tissue showed a positive reaction for cytokeratin （CK） 18, but not for CK19, vimentin, estrogen and progesterone receptors. Monoclonality was demonstrated for the lesion, confirming the diagnosis of an LCA. Clonality analysis is helpful for its distinction from focal nodular hyperplasia.K
基金supported by grants from the National Science Fund for Distinguished Young Scholars(NSFC No.71025005)the National Natural Science Foundation of China(NSFC No.71433001 and NSFC No.71301006)the National Program for Support of Top-Notch Young Professionals and the Fundamental Research Funds for the Central Universities in BUCT.
文摘To avoid credit fraud,social credit within an economic system has become an increasingly important criterion for the evaluation of economic agent activity and guaranteeing the development of a market economy with minimal supervision costs.This paper provides a comprehensive review of the social credit literature from the perspectives of theoretical foundation,scoring methods,and regulatory mechanisms.The study considers the credit of various economic agents within the social credit system such as countries(or governments),corporations,and individuals and their credit variations in online markets(i.e.,network credit).A historical review of the theoretical(or model)development of economic agents is presented together with significant works and future research directions.Some interesting conclusions are summarized from the literature review.(1)Credit theory studies can be categorized into traditional and emerging schools both focusing on the economic explanation of social credit in conjunction with creation and evolution mechanisms.(2)The most popular credit scoring methods include expert systems,econometric models,artificial intelligence(AI)techniques,and their hybrid forms.Evaluation indexes should vary across different target agents.(3)The most pressing task for regulatory mechanisms that supervise social credit to avoid credit fraud is the establishment of shared credit databases with consistent data standards.
基金supported in part by the Big Data Analytics Laboratory(BDALAB)at the Institute of Business Administration under the research grant approved by the Higher Education Commission of Pakistan(www.hec.gov.pk)the Darbi company(www.darbi.io)
文摘This paper focuses on facilitating state-of-the-art applications of big data analytics(BDA) architectures and infrastructures to telecommunications(telecom) industrial sector.Telecom companies are dealing with terabytes to petabytes of data on a daily basis. Io T applications in telecom are further contributing to this data deluge. Recent advances in BDA have exposed new opportunities to get actionable insights from telecom big data. These benefits and the fast-changing BDA technology landscape make it important to investigate existing BDA applications to telecom sector. For this, we initially determine published research on BDA applications to telecom through a systematic literature review through which we filter 38 articles and categorize them in frameworks, use cases, literature reviews, white papers and experimental validations. We also discuss the benefits and challenges mentioned in these articles. We find that experiments are all proof of concepts(POC) on a severely limited BDA technology stack(as compared to the available technology stack), i.e.,we did not find any work focusing on full-fledged BDA implementation in an operational telecom environment. To facilitate these applications at research-level, we propose a state-of-the-art lambda architecture for BDA pipeline implementation(called Lambda Tel) based completely on open source BDA technologies and the standard Python language, along with relevant guidelines.We discovered only one research paper which presented a relatively-limited lambda architecture using the proprietary AWS cloud infrastructure. We believe Lambda Tel presents a clear roadmap for telecom industry practitioners to implement and enhance BDA applications in their enterprises.
基金supported by two research grants provided by the Karachi Institute of Economics and Technology(KIET)the Big Data Analytics Laboratory at the Insitute of Business Administration(IBAKarachi)。
文摘The advent of healthcare information management systems(HIMSs)continues to produce large volumes of healthcare data for patient care and compliance and regulatory requirements at a global scale.Analysis of this big data allows for boundless potential outcomes for discovering knowledge.Big data analytics(BDA)in healthcare can,for instance,help determine causes of diseases,generate effective diagnoses,enhance Qo S guarantees by increasing efficiency of the healthcare delivery and effectiveness and viability of treatments,generate accurate predictions of readmissions,enhance clinical care,and pinpoint opportunities for cost savings.However,BDA implementations in any domain are generally complicated and resource-intensive with a high failure rate and no roadmap or success strategies to guide the practitioners.In this paper,we present a comprehensive roadmap to derive insights from BDA in the healthcare(patient care)domain,based on the results of a systematic literature review.We initially determine big data characteristics for healthcare and then review BDA applications to healthcare in academic research focusing particularly on No SQL databases.We also identify the limitations and challenges of these applications and justify the potential of No SQL databases to address these challenges and further enhance BDA healthcare research.We then propose and describe a state-of-the-art BDA architecture called Med-BDA for healthcare domain which solves all current BDA challenges and is based on the latest zeta big data paradigm.We also present success strategies to ensure the working of Med-BDA along with outlining the major benefits of BDA applications to healthcare.Finally,we compare our work with other related literature reviews across twelve hallmark features to justify the novelty and importance of our work.The aforementioned contributions of our work are collectively unique and clearly present a roadmap for clinical administrators,practitioners and professionals to successfully implement BDA initiatives in their organizations.
文摘BACKGROUND The inflammatory myofibroblastic tumor(IMT)is a rare,idiopathic,usually benign,mass-forming disease with myofibroblastic proliferation and a varying amount of inflammatory cells.Although it can affect various organs,the biliary tract is a rare localization of primary IMT,clinically,endoscopically and radiologically imitating cholangiocarcinoma.The treatment options are based only on clinical practice experience.CASE SUMMARY A 70-year-old woman was referred to our center due to progressive fatigue,weight loss,abdominal pain,night sweats,and elevated liver enzymes.Magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography(ERCP)revealed proximal common hepatic duct and hilar biliary strictures extending bilaterally to lobular bile ducts.Although initial clinical,endoscopic and radiological signs were typical for hilar cholangiocarcinoma,histological examination showed no signs of malignancy.In total,8 biopsies using different approaches were performed(several biopsies from dominant stricture during ERCP and direct cholangioscopy;ultrasound-guided liver biopsy;diagnostic laparoscopy with liver and lymph node biopsies).Histological examination revealed signs of IMT,and the final diagnosis of biliary IMT was stated.Although IMT is usually a benign disease,in our case,it was complicated.All pharmacological treatment measures were ineffective.The patient still needs permanent stenting,suffers from recurrent infections and mechanical jaundice.Despite that,the patient already survived 24 mo.CONCLUSION IMT presenting with hilar biliary strictures is a unique diagnostic and clinical challenge as it is indistinguishable from cholangiocarcinoma,and there are no evidence-based treatment options.Our goal is to increase the understanding of this rare disease and its possible course.
基金supported by the Ministry of Higher Education(MoHE)Malaysia under the Fundamental Research Grant Scheme(No.FRGS/1/2021/SS0/UM/02/6)the Universiti Malaya Research University Grant(No.RU004A-2020).
文摘Biotechnology policies and regulations must be revised and updated to reflect the most recent advances in plantbreeding technology. New Plant Breeding Techniques(NPBT) such as gene editing have been applied to address the myriad of challenges in plant breeding, while the use of NPBT as emerging biotechnological tools raises legal and ethical concerns. This study aims to highlight how gene editing is operationalized in the existing literature and examine the critical issues of ethical and legal issues of gene editing for plant breeding. We carried out a systematic literature review(SLR) to provide the current states of ethical and legal discourses surrounding this topic. We also identified critical research priority areas and policy gaps that must be addressed when designing the future governance of gene editing in plant breeding.
基金Supported by Zhongshan Bureau of Science and Technology,No.2017B1044and No.2017SYF04.
文摘BACKGROUND Lymphoepithelioma-like carcinoma(LELC),a rare and unique variant of liver cancer,can be divided into lymphoepithelioma-like hepatocellular carcinoma and lymphoepithelioma-like intrahepatic cholangiocarcinoma.Dense lymphocytic infiltration is its characteristic pathological feature.In recent years,the number of reported cases of this type has increased each year.Studies have shown that lymphoepithelioma-like cholangiocarcinoma occurs more frequently in Asian women;LELC is associated with Epstein–Barr virus infection of liver cells of epithelial origin.Existing research shows that the prognosis of this tumour is good.CASE SUMMARY A 38-year-old female patient was hospitalized after 3 mo of abdominal pain and nausea.She had been infected with hepatitis B virus more than 10 years prior.The patient was hospitalized on January 21,2022.Magnetic resonance imaging showed a 36 mm×28 mm mass under the envelope of the left inner lobe of the liver.No metastasis of lymph nodes or other organs was observed.After left hemihepatectomy,biopsy and immunohistochemistry yielded a final diagnosis of lymphoepithelial hepatocellular carcinoma.After 12 mo of outpatient follow-up and chemotherapy,no tumour metastases were found on the latest computed tomography examination.CONCLUSION Herein,the patient was treated surgically and then followed up as an outpatient for 12 mo.This case will further expand our overall knowledge of the diagnosis and treatment of this rare tumor.
文摘BACKGROUND Gastroenteropancreatic neuroendocrine tumours(GEP-NETs)are slow-growing cancers that arise from diffuse endocrine cells in the gastrointestinal tract(GINETs)or the pancreas(P-NETs).They are relatively uncommon,accounting for 2%of all gastrointestinal malignancies.The usual treatment options in advanced GEP-NET patients with metastatic disease include chemotherapy,biological therapies,and peptide receptor radionuclide therapy.Understanding the impact of treatment on GEP-NET patients is paramount given the nature of the disease.Health-related quality of life(HRQoL)is increasingly important as a concept reflecting the patients’perspective in conjunction with the disease presentation,severity and treatment.AIM To conduct a systematic literature review to identify literature reporting HRQoL data in patients with GEP-NETs between January 1985 and November 2019.METHODS The PRISMA guiding principles were applied.MEDLINE,Embase and the Cochrane library were searched.Data extracted from the publications included type of study,patient population data(mid-gut/hind-gut/GI-NET/P-NET),sample size,intervention/comparators,HRQoL instruments,average and data spread of overall and sub-scores,and follow-up time for data collection.RESULTS Forty-three publications met the inclusion criteria.The heterogeneous nature of the different study populations was evident;the percentage of female participants ranged between 30%-60%,whilst average age ranged from 53.8 to 67.0 years.Eight studies investigated GI-NET patients only,six studies focused exclusively on P-NET patients and the remaining studies involved both patient populations or did not report the location of the primary tumour.The most commonly used instrument was the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-C30(n=28)with consistent results across studies;the GI-NET-specific module Quality of Life Questionnaire-GINET21 was used in six of these studies.A number of randomised trials demonstrated no HRQoL changes between active treatment and placebo arms.The Phase III NETTER-1 study provides the best data available for advanced GEP-NET patients;it shows that peptide receptor radionuclide therapy can significantly improve GEP-NET patients’HRQoL.CONCLUSION HRQoL instruments offer a means to monitor patients’general disease condition,disease progression and their physical and mental well-being.Instruments including the commonly used European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-C30 and GINET21 lack,however,validation and a defined minimal clinical important difference specifically for GINET and P-NET patients.
文摘CLINICAL STUDIES Clinical studies on Chinese herbal medicine(CHM)in lung cancer(LC)have largely been on anumber of basic formulae selected by syndrome(Zheng)differentiation,or specific formula basedon clinical experience.There have also been anumber of studies comparing combination ofCHMs with either chemotherapy or radiotherapywith chemotherapy or radiotherapy alone,to as-sess any additional benefits or synergistic outcomesof the combination.
文摘BACKGROUND Isolated splenic metastasis is a rare clinical entity.Multiple metastases in the spleen after radical colon resection in a patient who subsequently underwent a second local resection for isolated metachronous splenic metastasis are exceedingly rare.CASE SUMMARY We report a colon cancer patient who underwent laparoscopic radical colon resection 14 mo previously,and subsequently underwent a second local resection due to local recurrence detected by elevated serum carcinoembryonic antigen(CEA)and positron emission tomography(PET).However,multiple metastases in the spleen were found 7 mo later by elevated serum CEA and PET-magnetic resonance imaging.Then the patient underwent total laparoscopic splenectomy.Local tumor recurrence and splenic metastasis from colorectal cancer(CRC)were found by postoperative pathology.Genetic analysis of these recurrent and metastatic tissues showed KRAS exon2,APC exon16 and TP53 exon6 missense mutations,but no mutations of NRAS,KRAF,EGFR,ERBB2,MET,MLH1,MSH2 and MSH6 were detected.Chemotherapy and target therapy were administered after multiple disciplinary team(MDT)consultation,and no tumor recurrence has been observed to date.We also reviewed the literature by conducting a search of the PubMed database using the following key words:CRC,splenic metastasis,isolated,and review.We identified 34 relevant papers,which included 28 cases of metachronous metastasis and 6 cases of simultaneous metastasis.CONCLUSION Close monitoring of serum CEA levels is crucial for the detection of isolated splenic metastases after colon surgery.In terms of overall survival and progression-free survival,MDT plays an important role in the entire process of disease management.
