[Objectives]To study the immediate-release mechanism of dehydrotrametenolic acid and dehydroeburicoic acid in Poriae Cutis total triterpenoids tablets by liquid-solid compacts technique.[Methods] Taking dehydrotramete...[Objectives]To study the immediate-release mechanism of dehydrotrametenolic acid and dehydroeburicoic acid in Poriae Cutis total triterpenoids tablets by liquid-solid compacts technique.[Methods] Taking dehydrotrametenolic acid and dehydroeburicoic acid as indicators,differences in dissolution were compared between liquid-solid compressed tablets and crude drug of total triterpenoids in Poriae Cutis;crude drug,powder of liquid-solid compressed tablets and excipients of liquid-solid compressed tablets were characterized by differential scanning calorimetry( DSC).[Results]Liquid-solid compact technique could significantly improve dissolution rate of dehydrotrametenolic acid and dehydroeburicoic acid. The total dissolution rate of dehydrotrametenolic acid and dehydroeburicoic acid in Poriae Cutis total triterpenoids tablets was 92%,t50( time for 50% total dissolution rate) and t_D( time for 63. 2% total dissolution rate) were 11. 18 min and 22. 71 min; the total dissolution rate of dehydrotrametenolic acid and dehydroeburicoic acid in crude drug of total triterpenoids was 29%,and t50 and t_D were231. 06 min and 359. 23 min. DSC showed that there was no mutual interaction between excipients and total triterpenoids in Poriae Cutis; on the DSC curve for powder of liquid-solid compressed tablets,the absorption peak vanished completely,indicating that the drug exists in the amorphous form in the liquid-solid powder.[Conclusions] Liquid-solid compact technique can increase the dissolution rate of total triterpenoids in Poriae Cutis and allow rapid release of poorly water soluble drugs.展开更多
The effect of boron on hot strips of low carbon steel produced by compact strip production （CSP） to reduce the strength to a certain degree was investigated, which is quite different from that of high-strength low a...The effect of boron on hot strips of low carbon steel produced by compact strip production （CSP） to reduce the strength to a certain degree was investigated, which is quite different from that of high-strength low alloy steel. The mechanical properties and microstructural evolution of the hot strip were studied using optical microscopy and tensile tests. By means of an electrolytic dissolution technique and Thermo-Cal calculation, the precipitates containing boron were analyzed and detected. From the electron backscattered diffraction analysis, it can be deciphered whether the microstructure has recrystallized or not. Furthermore, the effect of boron segregation on the recrystallization or non-recrystallization conditions can be distinguished. The segregation behavior of boron was investigated in boron-containing steel. The nonequilibrium segregation of boron during processing was discussed on the basis of the forming complexes with vacancies that migrate to the boundaries prior to annihilation, which was confirmed by the subsequent cold rolling with annealing experiments.展开更多
A compact pneumatic pulse-jet pump with a Venturi-like reverse flow diverter,which consists of a nozzle and diffuser,is designed for lifting and transporting a hazardous fluid through a narrow mounting hole.The pumpin...A compact pneumatic pulse-jet pump with a Venturi-like reverse flow diverter,which consists of a nozzle and diffuser,is designed for lifting and transporting a hazardous fluid through a narrow mounting hole.The pumping performance for a liquid mixture or a liquid-solid mixture is examined in terms of the effects of liquid viscosity,particle mass concentration,lifting height,and compression pressure.Results reveal that the pumping performance of the compact pneumatic pulse-jet pump is controlled by jet inertia and the flow resistance of the riser tube positioned after the diffuser.The capacity of the compact pneumatic pulse-jet pump increases with compression pressure and decreases with liquid viscosity.However,even for a liquid mixture with a high viscosity of 7.38 mPa·s,a pumping capacity of 170.7 L·h-1 was observed.For a liquid mixture,two dimensionless indices of performance were found to be the ratio of Euler numbers Euout/EuDV and the suction factor q.As the liquid-solid mixture was lifted to elevation of 6.74 m by the compact pump,the particle size distributions of the liquid-solid mixture in the tank and from the riser tube outlet were determined by a particle size analyzer and found to coincide well.展开更多
This paper presents a high-order coupled compact integrated RBF(CC IRBF)approximation based domain decomposition(DD)algorithm for the discretisation of second-order differential problems.Several Schwarz DD algorithms,...This paper presents a high-order coupled compact integrated RBF(CC IRBF)approximation based domain decomposition(DD)algorithm for the discretisation of second-order differential problems.Several Schwarz DD algorithms,including one-level additive/multiplicative and two-level additive/multiplicative/hybrid,are employed.The CCIRBF based DD algorithms are analysed with different mesh sizes,numbers of subdomains and overlap sizes for Poisson problems.Our convergence analysis shows that the CCIRBF two-level multiplicative version is the most effective algorithm among various schemes employed here.Especially,the present CCIRBF two-level method converges quite rapidly even when the domain is divided into many subdomains,which shows great promise for either serial or parallel computing.For practical tests,we then incorporate the CCIRBF into serial and parallel two-level multiplicative Schwarz.Several numerical examples,including those governed by Poisson and Navier-Stokes equations are analysed to demonstrate the accuracy and efficiency of the serial and parallel algorithms implemented with the CCIRBF.Numerical results show:(i)the CCIRBF-Serial and-Parallel algorithms have the capability to reach almost the same solution accuracy level of the CCIRBF-Single domain,which is ideal in terms of computational calculations;(ii)the CCIRBF-Serial and-Parallel algorithms are highly accurate in comparison with standard finite difference,compact finite difference and some other schemes;(iii)the proposed CCIRBF-Serial and-Parallel algorithms may be used as alternatives to solve large-size problems which the CCIRBF-Single domain may not be able to deal with.The ability of producing stable and highly accurate results of the proposed serial and parallel schemes is believed to be the contribution of the coarse mesh of the two-level domain decomposition and the CCIRBF approximation.It is noted that the focus of this paper is on the derivation of highly accurate serial and parallel algorithms for second-order differential problems.The scope of this work does not cover a thorough analysis of computational time.展开更多
The development of compaction bands in saturated soils, which is coupling-rate, inertial and pore-pressure-dependent, under axisymmetric loading was discussed, using a simple model and a matching technique at the movi...The development of compaction bands in saturated soils, which is coupling-rate, inertial and pore-pressure-dependent, under axisymmetric loading was discussed, using a simple model and a matching technique at the moving boundary of a band. It is shown that the development of compaction bands is dominated by the coupling-rate and pore-pressure effects of material. The soil strength makes the band shrinking, whilst pore pressure diffusion makes the band expand. Numerical simulations were carried out in this paper.展开更多
A compact self-isolated Multi Input Multi Output (MIMO) antennaarray is presented for 5G mobile phone devices. The proposed antenna systemis operating at the 3.5 GHz band (3400–3600 MHz) and consists of eight antenna...A compact self-isolated Multi Input Multi Output (MIMO) antennaarray is presented for 5G mobile phone devices. The proposed antenna systemis operating at the 3.5 GHz band (3400–3600 MHz) and consists of eight antennaelements placed along two side edges of a mobile device, which meets the currenttrend requirements of full-screen smartphone devices. Each antenna element isdivided into two parts, a front part and back part. The front part consists of anI-shaped feeding line and a modified Hilbert fractal monopole antenna, whereasthe back part is an L-shaped element shorted to the system ground by a0.5 mm short stub. A desirable compactness can be obtained by utilizing the Hilbert space-filling property where the antenna element’s overall planar size printedon the side-edge frame is just (9.57 mm × 5.99 mm). The proposed MIMO antenna system has been simulated, analyzed, fabricated and tested. Based on the selfisolated property, good isolation (better than 15 dB) is attained without employingadditional decoupling elements and/or isolation techniques, which increases system complexity and reduces the antenna efficiency. The scattering parameters,antenna efficiencies, antenna gains, and antenna radiation characteristics areinvestigated to assess the proposed antenna performance. For evaluating the proposed antenna array system performance, the Envelope Correlation Coefficients(ECCs), Mean Effective Gains (MEGs) and channel capacity are calculated.Desirable antenna and MIMO performances are evaluated to confirm the suitability of the proposed MIMO antenna system for 5G mobile terminals.展开更多
With the continuous growth of Chinas national economy, the development of Chinas road and bridge construction industry has also gained good development space, and advanced road construction technology has also been de...With the continuous growth of Chinas national economy, the development of Chinas road and bridge construction industry has also gained good development space, and advanced road construction technology has also been developed one after another. On this basis, the paper also focuses on the analysis of the basic pavement rolling compaction technology of municipal road and bridge projects in our country. Firstly, the theoretical application foundation of the basic pavement rolling compaction technology of municipal road and bridge projects in our country is analyzed. Secondly, the specific process of the basic pavement rolling compaction technology in municipal facilities projects is analyzed. Finally, the application focus of the construction method is further discussed, which involves the control of material yard, soil moisture content, structural layer uniformity and roller usage control, in order to strive to improve the overall construction quality of municipal road and bridge construction in our country.展开更多
基金Supported by Project of National Natural Science Foundation of Shandong Province(ZR2015PH015)
文摘[Objectives]To study the immediate-release mechanism of dehydrotrametenolic acid and dehydroeburicoic acid in Poriae Cutis total triterpenoids tablets by liquid-solid compacts technique.[Methods] Taking dehydrotrametenolic acid and dehydroeburicoic acid as indicators,differences in dissolution were compared between liquid-solid compressed tablets and crude drug of total triterpenoids in Poriae Cutis;crude drug,powder of liquid-solid compressed tablets and excipients of liquid-solid compressed tablets were characterized by differential scanning calorimetry( DSC).[Results]Liquid-solid compact technique could significantly improve dissolution rate of dehydrotrametenolic acid and dehydroeburicoic acid. The total dissolution rate of dehydrotrametenolic acid and dehydroeburicoic acid in Poriae Cutis total triterpenoids tablets was 92%,t50( time for 50% total dissolution rate) and t_D( time for 63. 2% total dissolution rate) were 11. 18 min and 22. 71 min; the total dissolution rate of dehydrotrametenolic acid and dehydroeburicoic acid in crude drug of total triterpenoids was 29%,and t50 and t_D were231. 06 min and 359. 23 min. DSC showed that there was no mutual interaction between excipients and total triterpenoids in Poriae Cutis; on the DSC curve for powder of liquid-solid compressed tablets,the absorption peak vanished completely,indicating that the drug exists in the amorphous form in the liquid-solid powder.[Conclusions] Liquid-solid compact technique can increase the dissolution rate of total triterpenoids in Poriae Cutis and allow rapid release of poorly water soluble drugs.
基金This work was financially supported by the National Natural Science Foundation of China (No. 50774110)Fok Ying Tong Edu-cation Foundation (No.104017).
文摘The effect of boron on hot strips of low carbon steel produced by compact strip production （CSP） to reduce the strength to a certain degree was investigated, which is quite different from that of high-strength low alloy steel. The mechanical properties and microstructural evolution of the hot strip were studied using optical microscopy and tensile tests. By means of an electrolytic dissolution technique and Thermo-Cal calculation, the precipitates containing boron were analyzed and detected. From the electron backscattered diffraction analysis, it can be deciphered whether the microstructure has recrystallized or not. Furthermore, the effect of boron segregation on the recrystallization or non-recrystallization conditions can be distinguished. The segregation behavior of boron was investigated in boron-containing steel. The nonequilibrium segregation of boron during processing was discussed on the basis of the forming complexes with vacancies that migrate to the boundaries prior to annihilation, which was confirmed by the subsequent cold rolling with annealing experiments.
文摘A compact pneumatic pulse-jet pump with a Venturi-like reverse flow diverter,which consists of a nozzle and diffuser,is designed for lifting and transporting a hazardous fluid through a narrow mounting hole.The pumping performance for a liquid mixture or a liquid-solid mixture is examined in terms of the effects of liquid viscosity,particle mass concentration,lifting height,and compression pressure.Results reveal that the pumping performance of the compact pneumatic pulse-jet pump is controlled by jet inertia and the flow resistance of the riser tube positioned after the diffuser.The capacity of the compact pneumatic pulse-jet pump increases with compression pressure and decreases with liquid viscosity.However,even for a liquid mixture with a high viscosity of 7.38 mPa·s,a pumping capacity of 170.7 L·h-1 was observed.For a liquid mixture,two dimensionless indices of performance were found to be the ratio of Euler numbers Euout/EuDV and the suction factor q.As the liquid-solid mixture was lifted to elevation of 6.74 m by the compact pump,the particle size distributions of the liquid-solid mixture in the tank and from the riser tube outlet were determined by a particle size analyzer and found to coincide well.
文摘This paper presents a high-order coupled compact integrated RBF(CC IRBF)approximation based domain decomposition(DD)algorithm for the discretisation of second-order differential problems.Several Schwarz DD algorithms,including one-level additive/multiplicative and two-level additive/multiplicative/hybrid,are employed.The CCIRBF based DD algorithms are analysed with different mesh sizes,numbers of subdomains and overlap sizes for Poisson problems.Our convergence analysis shows that the CCIRBF two-level multiplicative version is the most effective algorithm among various schemes employed here.Especially,the present CCIRBF two-level method converges quite rapidly even when the domain is divided into many subdomains,which shows great promise for either serial or parallel computing.For practical tests,we then incorporate the CCIRBF into serial and parallel two-level multiplicative Schwarz.Several numerical examples,including those governed by Poisson and Navier-Stokes equations are analysed to demonstrate the accuracy and efficiency of the serial and parallel algorithms implemented with the CCIRBF.Numerical results show:(i)the CCIRBF-Serial and-Parallel algorithms have the capability to reach almost the same solution accuracy level of the CCIRBF-Single domain,which is ideal in terms of computational calculations;(ii)the CCIRBF-Serial and-Parallel algorithms are highly accurate in comparison with standard finite difference,compact finite difference and some other schemes;(iii)the proposed CCIRBF-Serial and-Parallel algorithms may be used as alternatives to solve large-size problems which the CCIRBF-Single domain may not be able to deal with.The ability of producing stable and highly accurate results of the proposed serial and parallel schemes is believed to be the contribution of the coarse mesh of the two-level domain decomposition and the CCIRBF approximation.It is noted that the focus of this paper is on the derivation of highly accurate serial and parallel algorithms for second-order differential problems.The scope of this work does not cover a thorough analysis of computational time.
文摘The development of compaction bands in saturated soils, which is coupling-rate, inertial and pore-pressure-dependent, under axisymmetric loading was discussed, using a simple model and a matching technique at the moving boundary of a band. It is shown that the development of compaction bands is dominated by the coupling-rate and pore-pressure effects of material. The soil strength makes the band shrinking, whilst pore pressure diffusion makes the band expand. Numerical simulations were carried out in this paper.
文摘A compact self-isolated Multi Input Multi Output (MIMO) antennaarray is presented for 5G mobile phone devices. The proposed antenna systemis operating at the 3.5 GHz band (3400–3600 MHz) and consists of eight antennaelements placed along two side edges of a mobile device, which meets the currenttrend requirements of full-screen smartphone devices. Each antenna element isdivided into two parts, a front part and back part. The front part consists of anI-shaped feeding line and a modified Hilbert fractal monopole antenna, whereasthe back part is an L-shaped element shorted to the system ground by a0.5 mm short stub. A desirable compactness can be obtained by utilizing the Hilbert space-filling property where the antenna element’s overall planar size printedon the side-edge frame is just (9.57 mm × 5.99 mm). The proposed MIMO antenna system has been simulated, analyzed, fabricated and tested. Based on the selfisolated property, good isolation (better than 15 dB) is attained without employingadditional decoupling elements and/or isolation techniques, which increases system complexity and reduces the antenna efficiency. The scattering parameters,antenna efficiencies, antenna gains, and antenna radiation characteristics areinvestigated to assess the proposed antenna performance. For evaluating the proposed antenna array system performance, the Envelope Correlation Coefficients(ECCs), Mean Effective Gains (MEGs) and channel capacity are calculated.Desirable antenna and MIMO performances are evaluated to confirm the suitability of the proposed MIMO antenna system for 5G mobile terminals.
文摘With the continuous growth of Chinas national economy, the development of Chinas road and bridge construction industry has also gained good development space, and advanced road construction technology has also been developed one after another. On this basis, the paper also focuses on the analysis of the basic pavement rolling compaction technology of municipal road and bridge projects in our country. Firstly, the theoretical application foundation of the basic pavement rolling compaction technology of municipal road and bridge projects in our country is analyzed. Secondly, the specific process of the basic pavement rolling compaction technology in municipal facilities projects is analyzed. Finally, the application focus of the construction method is further discussed, which involves the control of material yard, soil moisture content, structural layer uniformity and roller usage control, in order to strive to improve the overall construction quality of municipal road and bridge construction in our country.
