Sound speed is essential for leakage detection in liquid pipelines when using acoustic methods,which can be significantly influenced by gas bubbles generated from leakage.The propagation characteristics and mechanism ...Sound speed is essential for leakage detection in liquid pipelines when using acoustic methods,which can be significantly influenced by gas bubbles generated from leakage.The propagation characteristics and mechanism of acoustic waves in horizontal liquid pipelines containing gas bubbles are studied in detail in the present paper.The effect of sound wave frequency,bubble size and bubble distribution pattern on sound speed is studied through numerical simulations.The results show that the acoustic wave generated by leakage of liquid pipelines containing gas bubbles is a multi-frequency signal,and the energy of the signal is mainly concentrated within 200 Hz.In the low-frequency range,the propagation of sound waves has almost no dispersion in bubbly liquid.Sound speed at a certain void fraction is not constant,which is related to the bubble size and distribution pattern.The bubble size affects the gasliquid heat transfer equilibrium,during which sound speed is affected.For this reason,a thermodynamic correction factor is proposed,which enables the accuracy of the sound speed calculation to reach98.2%.What's more,sound speed increases non-linearly with the reduction of the bubble distribution space in the pipeline axial direction.This paper establishes a theoretical calculation model of sound speed based on the bubble distribution pattern in the pipeline axial direction,which is in good agreement with the numerical calculation results.The results of this paper provide the basis for applying acoustic leak detection technology in liquid pipelines containing gas bubbles.展开更多
This study investigates the seismic response mitigation of an offshore jacket platform via a novel damping system,the bidirectional tuned liquid column gas damper(BTLCGD).To efficiently model the complex platform stru...This study investigates the seismic response mitigation of an offshore jacket platform via a novel damping system,the bidirectional tuned liquid column gas damper(BTLCGD).To efficiently model the complex platform structure,an equivalent single degree of freedom approach was employed.Since the mass contribution of the first mode of the platform is more than 90%,this simplification significantly reduces the computational burden while maintaining accuracy.Therefore,this structure was modeled and analyzed on a scale of 1 to 36 using the Froudian law.To address the limitations of conventional tuned liquid column gas dampers(TLCGDs),which are susceptible to the directionality of seismic excitations,BTLCGD was proposed.This innovative damper is designed to operate effectively in two orthogonal directions,thereby improving seismic performance.Through numerical simulations,the performance of both TLCGD and BTLCGD was evaluated under seismic loading.The results demonstrated that BTLCGD significantly outperforms TLCGD in terms of reducing structural responses,particularly in the direction where TLCGD is ineffective.Furthermore,BTLCGD offers advantages in terms of installation and space requirements.The results of this research offer valuable perspectives into the design and implementation of effective damping systems for offshore structures,contributing to enhanced structural integrity and safety.展开更多
Gas explosions are a frequent hazard in underground confined spaces in the process of urban development.Liquid sedimentary layers,commonly present in these environments,have not been sufficiently studied in terms of t...Gas explosions are a frequent hazard in underground confined spaces in the process of urban development.Liquid sedimentary layers,commonly present in these environments,have not been sufficiently studied in terms of their impact on explosion dynamics.This study aims to investigate how gas-liquid two-phase environments in confined underground spaces affect the explosion characteristics of natural gas.To achieve this,experiments are conducted to examine the propagation of natural gas explosions in water and diesel layers,focusing on the influence of liquid properties and the liquid fullness degree(Lx)on explosion behavior.The results indicate that the presence of a liquid layer after the initial ignition stage significantly attenuates both the peak overpressure and the rise speed of pressure,in comparison to the natural gas conditions.During the subsequent explosive reaction,the evaporation and combustion of the diesel surface resulted in a distinct double-peak pressure rise profile in the diesel layer,with the second peak notably exceeding the first peak.Under conditions with a liquid sedimentary layer,the flame propagation velocities range from 6.53 to 34.1 m/s,while the overpressure peaks vary between 0.157 and 0.255 MPa.The explosion duration in both the water and diesel layer environments is approximately twice as long as that of the natural gas explosion,although the underlying mechanisms differ.In the diesel layer,the prolonged explosion time is attributed to the evaporation and combustion of the diesel,while in the water layer,the flame propagation velocity is significantly reduced.Under the experimental conditions,the maximum explosion energy reached 7.15×10~6J,corresponding to a TNT equivalent of 1.7.The peak overpressure surpassed the threshold for human fatality as defined by overpressure standards,posing a potential risk of damage to large steel-frame structures.The explosion shockwave in diesel layer conditions(L_(d)=0%,5%,7.5%,12.5%)and water layer(L_(w)=12.5%)conditions is observed to be sufficient to damage earthquake-resistant reinforced concrete.This study investigates the impact of sediment layer thickness and composition on gas explosions,and evaluates the associated explosion energy to assess human injuries and structural damage in underground environments.The findings of this study provide a scientific reference for urban underground safety.展开更多
The agitated thin-film evaporator(ATFE)plays a crucial role in evaporation and concentration processes.The design of the scraper for processing high-viscosity non-Newtonian fluids in the ATFE is complex.The intricate ...The agitated thin-film evaporator(ATFE)plays a crucial role in evaporation and concentration processes.The design of the scraper for processing high-viscosity non-Newtonian fluids in the ATFE is complex.The intricate scraping action of the scraper introduces gas into the liquid film,leading to the formation of a gas ring along the wall.This process subsequently reduces wall heat flow,thereby affecting heat transfer.Computational fluid dynamics(CFD)is used to simulate the flow field of the non-Newtonian fluid in the ATFE.The investigation focuses on understanding the mechanism behind the formation of gas rings in the liquid film and proposes methods to prevent their formation.The results demonstrate a transition of the gas from a gas ring suspended in the liquid to a gas ring attached to the wall after entering the liquid film.The scraping action around the circumference of the scraper helps to expel gas rings,indicating the necessity of adjusting the scraper arrangement and increasing the frequency of scraping to enhance gas ring expulsion.The spiral motion of the bow wave serves as the source of gas entry into the liquid film.Therefore,the rotation speed can appropriately increase to reduce the size of the bow wave,thereby inhibiting the formation of the gas ring from the source.This research investigates the mechanism of gas ring generation and expulsion,offering theoretical guidance for processing high-viscosity non-Newtonian materials in the flow field of the ATFE.展开更多
In photothermal power(solar energy)generation systems,purging residual molten salt from pipelines using highpressure gas poses a significant challenge,particularly in clearing the bottom of regulating valves.Ineffecti...In photothermal power(solar energy)generation systems,purging residual molten salt from pipelines using highpressure gas poses a significant challenge,particularly in clearing the bottom of regulating valves.Ineffective purging can lead to crystallization of the molten salt,resulting in blockages.To address this issue,understanding the gas-liquid two-phase flow dynamics during high-pressure gas purging is crucial.This study utilizes the Volume of Fluid(VOF)model and adaptive dynamic grids to simulate the gas-liquid two-phase flow during the purging process in a DN50 PN50 conventional molten salt regulating valve.Initially,the reliability of the CFD simulations is validated through comparisons with experimental data and findings from the literature.Subsequently,simulation experiments are conducted to analyze the effects of various factors,including purge flow rates,initial liquid accumulation masses,purge durations,and the profiles of the valve bottom flow channels.The results indicate that the purging process comprises four distinct stages:Initial violent surge stage,liquid discharge stage,liquid partial fallback stage,liquid dissipation stage.For an initial liquid height of 17 mm at the bottom of the valve,the critical purge flow rate lies between 3 and 5 m/s.Notably,the critical purge flow rate is independent of the initial liquid accumulation mass.As the purge gas flow rate increases,the volume of liquid discharged also increases.Beyond the critical purge flow rate,higher purge gas velocities lead to shorter purge durations.Interestingly,the residual liquid mass after purging remains unaffected by the initial liquid accumulation.Additionally,the flow channel profile at the bottom of the valve significantly influences both the critical purge speed and the efficiency of the purging process.展开更多
In this work,we proposed a strategy for the hydrolysis of native corn starch after the treatment of corn starch in an ionic liquid aqueous solution,and it is an awfully“green”and simple means to obtain starch with l...In this work,we proposed a strategy for the hydrolysis of native corn starch after the treatment of corn starch in an ionic liquid aqueous solution,and it is an awfully“green”and simple means to obtain starch with low molecular weight and amorphous state.X-ray diffraction results revealed that the natural starch crystalline region was largely disrupted by ionic liquid owing to the broken intermolecular and intramolecular hydrogen bonds.After hydrolysis,the morphology of starch changed from particles of native corn starch into little pieces,and their molecular weight could be effectively regulated during the hydrolysis process,and also the hydrolyzed starch samples exhibited decreased thermal stability with the extension of hydrolysis time.This work would counsel as a powerful tool for the development of native starch in realistic applications.展开更多
Designing Fischer-Tropsch synthesis(FTS)catalysts to selectively produce liquid hydrocarbon fuels is a crucial challenge.Herein,we selectively introduced Co nanoparticles(NPs)into the micropores and mesopores of an or...Designing Fischer-Tropsch synthesis(FTS)catalysts to selectively produce liquid hydrocarbon fuels is a crucial challenge.Herein,we selectively introduced Co nanoparticles(NPs)into the micropores and mesopores of an ordered mesoporous MFI zeolite(OMMZ)through impregnation,which controlled the carbon number distribution in the FTS products by tuning the position of catalytic active sites in differently sized pores.The Co precursors coordinated by acetate with a size of 9.4×4.2×2.5Åand by 2,2'-bipyridine with a size of 9.5×8.7×7.9Å,smaller and larger than the micropores(ca.5.5Å)of MFI,made the Co species incorporated in OMMZ's micropores and mesopores,respectively.The carbon number products synthesized with the Co NPs confined in mesopores were larger than that in micropores.The high jet and diesel selectivities of 66.5%and 65.3%were achieved with Co NPs confined in micropores and mesopores of less acidic Na-type OMMZ,respectively.Gasoline and jet selectivities of 76.7%and 70.8%were achieved with Co NPs confined in micropores and mesopores of H-type OMMZ with Brönsted acid sites,respectively.A series of characterizations revealed that the selective production of diesel and jet fuels was due to the C-C cleavage suppressing of heavier hydrocarbons by the Co NPs located in mesopores.展开更多
The Early Eocene Sui Main Limestone(SML)reservoirs in the Qadirpur area are significant hydrocarbon-producing formations but suffer from low permeability and poor reservoir characteristics that lead to well abandonmen...The Early Eocene Sui Main Limestone(SML)reservoirs in the Qadirpur area are significant hydrocarbon-producing formations but suffer from low permeability and poor reservoir characteristics that lead to well abandonment.Although commonly used,conventional stimulation techniques such as hydraulic fracturing and acidizing pose environmental risks,high costs,and sensitivity to fluctuations in crude oil prices.Meanwhile,cryogenic liquid nitrogen(LN2)treatment has emerged as an innovative,eco-friendly alternative due to its thermal shock effects,which enhance rock permeability and porosity.Herein,SML core samples are treated with LN2 for 30,60,and 90 min to obtain samples designated as SML_30,SML_60,and SML_90,respectively.These are examined using X-ray diffraction(XRD),atomic force microscopy(AFM),scanning electron microscopy(SEM),energy dispersive spectroscopy(EDS),nanoindentation,and petrophysical measurements to evaluate the changes in their petrophysical,morphological,and micromechanical properties.The post-treatment analysis reveals that LN2 cooling effectively induces micro-cracks,with fracture widths of up to 40μm,along with a substantial increase in surface roughness from 350 to 942 nm.Additionally,micromechanical analysis indicates notable changes in the indentation modulus due to stress-induced alterations in the rock matrix.At optimal LN2 exposure(90 min),the porosity and permeability of the SML sample is more than doubled.These findings provide valuable insights into LN2-induced reservoir enhancements,thereby contributing to a better understanding of fluid flow behavior and hydrocarbon recovery in tight gas reservoirs.Thus,LN2 treatment presents a promising,cost-effective,and environmentally sustainable alternative to conventional stimulation methods.展开更多
Pediatric cancers are particularly significant due to their uncommon occurrence in children,driven by a variety of underlying factors.Because of their distinct molecular and genetic makeup,which makes early detection ...Pediatric cancers are particularly significant due to their uncommon occurrence in children,driven by a variety of underlying factors.Because of their distinct molecular and genetic makeup,which makes early detection challenging,they are linked to problems.Diagnostic methods like imaging and tissue biopsy are only effective when the tumor has reached a size that can be identified.The liquid biopsy technique,the least intrusive and most convenient diagnostic method,is the subject of this review.It focuses on the significance of single cell analysis in examining uncommon cancer types.The many biomarkers found in bodily fluids and the cancer types they are linked to in children have been assessed,as has the potential route towards early detection and cancer recurrence forecasting.Combining the single cell liquid biopsy with the newest technologies,such as computational and multi-omics approaches,which have improved the efficiency of processing massive and unique genetic data,appears promising.This article discusses on a number of case reports for uncommon pediatric malignancies,such as Neuroblastoma,Medulloblastoma,Wilms Tumor,Rhabdomyosarcoma,Ewing Sarcoma,and Retinoblastoma,as well as their liquid biopsy profiles.Furthermore,the findings raise ethical questions regarding the therapeutic application of the technology as well as possible difficulties related to clinical translation.The likelihood that this single cell liquid biopsy will be clinically validated and eventually used as a routine diagnostic tool for uncommon pediatric cancers will rise with the realistic approach to sensitivity monitoring,specificity upgrading,and optimization.展开更多
While desalination is a key solution for global freshwater scarcity,its implementation faces environmental challenges due to concentrated brine byproducts mainly disposed of via coastal discharge systems.Solar interfa...While desalination is a key solution for global freshwater scarcity,its implementation faces environmental challenges due to concentrated brine byproducts mainly disposed of via coastal discharge systems.Solar interfacial evaporation offers sustainable management potential,yet inevitable salt nucleation at evaporation interfaces degrades photothermal conversion and operational stability via light scattering and pathway blockage.Inspired by the mangrove leaf,we propose a photothermal 3D polydopamine and polypyrrole polymerized spacer fabric(PPSF)-based upward hanging model evaporation configuration with a reverse water feeding mechanism.This design enables zero-liquiddischarge(ZLD)desalination through phase-separation crystallization.The interconnected porous architecture and the rough surface of the PPSF enable superior water transport,achieving excellent solar-absorbing efficiency of 97.8%.By adjusting the tilt angle(θ),the evaporator separates the evaporation and salt crystallization zones via controlled capillary-driven brine transport,minimizing heat dissipation from brine discharge.At an optimal tilt angle of 52°,the evaporator reaches an evaporation rate of 2.81 kg m^(−2) h^(−1) with minimal heat loss(0.366 W)under 1-sun illumination while treating a 7 wt%waste brine solution.Furthermore,it sustains an evaporation rate of 2.71 kg m^(−2) h^(−1) over 72 h while ensuring efficient salt recovery.These results highlight a scalable,energy-efficient approach for sustainable ZLD desalination.展开更多
Automated classification of gas flow states in blast furnaces using top-camera imagery typically demands a large volume of labeled data,whose manual annotation is both labor-intensive and cost-prohibitive.To mitigate ...Automated classification of gas flow states in blast furnaces using top-camera imagery typically demands a large volume of labeled data,whose manual annotation is both labor-intensive and cost-prohibitive.To mitigate this challenge,we present an enhanced semi-supervised learning approach based on the Mean Teacher framework,incorporating a novel feature loss module to maximize classification performance with limited labeled samples.The model studies show that the proposed model surpasses both the baseline Mean Teacher model and fully supervised method in accuracy.Specifically,for datasets with 20%,30%,and 40%label ratios,using a single training iteration,the model yields accuracies of 78.61%,82.21%,and 85.2%,respectively,while multiple-cycle training iterations achieves 82.09%,81.97%,and 81.59%,respectively.Furthermore,scenario-specific training schemes are introduced to support diverse deployment need.These findings highlight the potential of the proposed technique in minimizing labeling requirements and advancing intelligent blast furnace diagnostics.展开更多
The inability to access brain tissue has greatly hindered our ability to study and care for individuals suffering from psychiatric and neurological conditions.Critics have questioned efforts to develop peripheral bloo...The inability to access brain tissue has greatly hindered our ability to study and care for individuals suffering from psychiatric and neurological conditions.Critics have questioned efforts to develop peripheral blood biomarkers in neurological and psychiatric disorders based on the assertion that disease pathology is limited to the brain.The discovery that all tissues,including the brain,release extracellular vesicles(Raposo and Stoorvogel,2013)and cell free DNAs(Chan et al.,2013)into various body fluids has provided a potential way to measure activity from inaccessible tissues like the central nervous system(CNS)and has given rise to the term“liquid biopsy.”The development of liquid biopsies that can diagnose and predict the course of psychiatric and neurological disorders would be transformative.The ability to predict episodic events such as mania,depression,and risk for suicide would be particularly useful for psychiatric care as it would enable the development of interventions that prevent mortality and improve outcomes.Additionally,biomarkers that are informative about drug response and aid in treatment decisions would be a significant advance in psychiatric care as it would prevent patients from having to endure multiple courses of ineffective treatments and side effects.展开更多
A series of bifunctional catalysts composed of a component for higher alcohol synthesis （Cu-CoMn oxides, CCM） and an acidic zeolite （SAPO-34, ZSM-5, Y, MCM-41） were prepared for production of liquid hydrocarbon di...A series of bifunctional catalysts composed of a component for higher alcohol synthesis （Cu-CoMn oxides, CCM） and an acidic zeolite （SAPO-34, ZSM-5, Y, MCM-41） were prepared for production of liquid hydrocarbon directly from a bio-syngas through a one-stage pro-cess. The effects of zeolite type, zeolite content, Si/Al ratio and preparation method on catalyst texture and its reaction performance were investigated. Higher selectivities and yields of liquid products were obtained by using bifunctional catalysts. The yields of liquid hydrocarbons decreased in the order CCM-ZSM-5〉CCM-SAPO-34〉CCM-Y〉CCM-MCM-41. CCM-ZSM-5 （20wt%, Si/Al=100） prepared by coprecipitation method displayed the optimal catalytic performance with the highest CO conversion （76%） and yield of liquid products （30%）. The catalysts were characterized by N2 adsorption/desorption, NH3-TPD, XRD, and H2-TPR analysis. The results showed that higher speci c surface areas and pore volumes of bifunctional catalysts were achieved by adding zeolites into CuCoMn precursors. Medium pore dimension and moderate acidity in CCM-ZSM-5 were observed, which proba-bly resulted in its excellent reaction performance. Additionally, a higher number of weaker acid sites （weak and/or medium acid sites） were formed by increasing ZSM-5 content in CCM-ZSM-5 or decreasing Si/Al ratio in ZSM-5. It was also seen that metal dispersion was higher and reducibility of metal ions was easier on the CCM-ZSM-5 catalyst prepared by coprecipitation. The higher alcohols-to-hydrocarbon process provides a promising route to hydrocarbon fuels via higher alcohols from syngas or biobased feedstocks.展开更多
Quantum mechanics and molecular dynamics are used to simulate guanidinium ionic liquids. Results show that the stronger interaction exists between guanidine cation and chlorine anion with interaction energy about 109....Quantum mechanics and molecular dynamics are used to simulate guanidinium ionic liquids. Results show that the stronger interaction exists between guanidine cation and chlorine anion with interaction energy about 109.216 kcal/mol. There are two types of spatial distribution for the title system： middle and top. Middle mode is a more stable conformation according to energy and geometric distribution. It is also verified by radial distribution function. The continuous increase of carbon dioxide （CO2） does not affect the structure of ionic liquids, but CO2 molecules are always captured by the cavity of ionic liquids.展开更多
Based on the solid-gas eutectic unidirectional solidification technique and the principle of unidirectional solidification of single-phase alloy, a new method for evaluating the diffusion coefficient of hydrogen in li...Based on the solid-gas eutectic unidirectional solidification technique and the principle of unidirectional solidification of single-phase alloy, a new method for evaluating the diffusion coefficient of hydrogen in liquid metals was proposed. Taking Cu-H2 system for example, the influences of argon partial pressure and superheat degree of melt on the diffusion coefficient of hydrogen in liquid metal were studied and the predicted values were similar to each other. The obtained temperature-dependent equation for diffusion coefficient of hydrogen in liquid copper is comparable with experimental data in literature, which validates the effectiveness of this method. The temperature-dependent equations for diffusion coefficient of hydrogen in liquid Mg, Si and Cu-34.6%Mn alloy were also evaluated by this method, along with the values at the melting point of each metal and alloy.展开更多
The non-uniformity of gas–liquid mixture is a critical issue which leads to the heat transfer deterioration of spiralwound heat exchangers(SWHEs).Two-phase mass flow rate and the content of gas are important paramete...The non-uniformity of gas–liquid mixture is a critical issue which leads to the heat transfer deterioration of spiralwound heat exchangers(SWHEs).Two-phase mass flow rate and the content of gas are important parameters as well as structural parameters which have prominent influences on flow distribution uniformity of SWHE shell side.In order to investigate the influences of these parameters,an experimental test system was built using water and air as mediums and a novel distributor named"tubes distributor"was designed.The effects of mass flow rate and the content of gas on two-phase distribution performance were analyzed,where the mass flow rate ranged from 28.4 to 171.9 kg·h-1 and the content of gas changed from 0.2 to 0.8,respectively.The results showed that the mixture mass flow rate considerably influenced the liquid distribution than that of gas phase and the larger mass flow rate exhibited the better distribution uniformity of two-phase flow.It was also found that the tubes distributor had the better two-phase uniformity when the content of gas was around 0.4.Tube diameter played an important role in the distribution of gas phase and slit width was more significant for the uniformity of liquid phase.展开更多
The main intention of the present study is to reduce wind, wave, and seismic induced vibrations of jacket- type offshore wind turbines （JOWTs） through a newly developed vibration absorber, called tuned liquid column...The main intention of the present study is to reduce wind, wave, and seismic induced vibrations of jacket- type offshore wind turbines （JOWTs） through a newly developed vibration absorber, called tuned liquid column gas damper （TLCGD）. Using a Simulink-based model, an analytical model is developed to simulate global behavior of JOWTs under different dynamic excitations. The study is followed by a parametric study to explore efficiency of the TLCGD in terms of nacelle acceleration reduction under wind, wave, and earthquake loads. Study results indicate that optimum frequency of the TLCGD is rather insensitive to excitation type. In addition, while the gain in vibration control from TLCGDs with higher mass ratios is generally more pronounced, heavy TLCGDs are more sensitive to their tuned frequency such that ill-regulated TLCGD with high mass ratio can lead to destructive results. It is revealed that a well regulated TLCGD has noticeable contribution to the dynamic response of the JOWT under any excitation.展开更多
The paper introduces gas to liquids (GTL) as a monetising option from a technology, marketing and project perspective. GTL is complementary to LNG and pipelines. At the same time, using natural gas as a source for fue...The paper introduces gas to liquids (GTL) as a monetising option from a technology, marketing and project perspective. GTL is complementary to LNG and pipelines. At the same time, using natural gas as a source for fuels in the form of GTL helps countries around the world to diversify their energy supplies. Furthermore, gas-based products are inherently cleaner than oil products. Shell's proprietary GTL technology or SMDS (Shell Middle Distillates Synthesis), is discussed in some detail. The paper also covers the challenges for successful implementation of GTL projects and why Shell is well positioned to take a lead in the industry on the basis of its long standing and broad experience in GTL research, plant operations, marketing and excellent track record in mega projects in the last thirty years. Shell's commitment to GTL is best demonstrated by the recent signing of a Heads of Agreement with Qatar Petroleum for the construction of the world's largest GTL plant. A key success factor is Shell's experience with marketing quantities of high quality GTL products from its 12,500 barrels per day plant at Bintulu, Malaysia since 1993. Further marketing opportunities will arise when new GTL capacity comes on-stream in the middle east when more quantities will become available to bulk users. Amongst the most interesting market will be automotive transportation, where clean GTL fuels can be positioned as an 'alternative fuel beyond oil' providing energy security to host countries. Shell is actively engaging with a number of regulators, automotive companies and governments worldwide including China, to demonstrate the performance of GTL and its cost effectiveness in reducing local emissions. An added benefit is that GTL can use existing infrastructure and requires no investment. Finally, the paper briefly discusses the coal to liquids (CTL) process as an alternative route to produce high quality GTL products and the key issues relating to the process.展开更多
This paper describes the application of ultrasound waves on hydrodynamics and mass transfer characteristics in the gas–liquid flow in a T-shape microreactor with a diameter of 800 μm. A 1.7 MHz piezoelectric transdu...This paper describes the application of ultrasound waves on hydrodynamics and mass transfer characteristics in the gas–liquid flow in a T-shape microreactor with a diameter of 800 μm. A 1.7 MHz piezoelectric transducer(PZT) was employed to induce the vibration in this microreactor. Liquid side volumetric mass transfer coefficients were measured by physical and chemical methods of CO_2 absorption into water and Na OH solution. The approach of absorption of CO_2 into a 1 mol·L^(-1) Na OH solution was used for analysis of interfacial areas. With the help of a photography system, the fluid flow patterns inside the microreactor were analyzed. The effects of superficial liquid velocity, initial concentration of Na OH, superficial CO_2 gas velocity and length of microreactor on the mass transfer rate were investigated. The comparison between sonicated and plain microreactors(microreactor with and without ultrasound) shows that the ultrasound wave irradiation has a significant effect on kLa and interfacial area at various operational conditions. For the microreactor length of 12 cm, ultrasound waves improved kLa and interfacial area about 21% and 22%, respectively. From this study, it can be concluded that ultrasound wave irradiation in microreactor has a great effect on the mass transfer rate. This study suggests a new enhancement technique to establish high interfacial area and kLa in microreactors.展开更多
基金supported by the National Natural Science Foundation of China[grant number 52274066]。
文摘Sound speed is essential for leakage detection in liquid pipelines when using acoustic methods,which can be significantly influenced by gas bubbles generated from leakage.The propagation characteristics and mechanism of acoustic waves in horizontal liquid pipelines containing gas bubbles are studied in detail in the present paper.The effect of sound wave frequency,bubble size and bubble distribution pattern on sound speed is studied through numerical simulations.The results show that the acoustic wave generated by leakage of liquid pipelines containing gas bubbles is a multi-frequency signal,and the energy of the signal is mainly concentrated within 200 Hz.In the low-frequency range,the propagation of sound waves has almost no dispersion in bubbly liquid.Sound speed at a certain void fraction is not constant,which is related to the bubble size and distribution pattern.The bubble size affects the gasliquid heat transfer equilibrium,during which sound speed is affected.For this reason,a thermodynamic correction factor is proposed,which enables the accuracy of the sound speed calculation to reach98.2%.What's more,sound speed increases non-linearly with the reduction of the bubble distribution space in the pipeline axial direction.This paper establishes a theoretical calculation model of sound speed based on the bubble distribution pattern in the pipeline axial direction,which is in good agreement with the numerical calculation results.The results of this paper provide the basis for applying acoustic leak detection technology in liquid pipelines containing gas bubbles.
文摘This study investigates the seismic response mitigation of an offshore jacket platform via a novel damping system,the bidirectional tuned liquid column gas damper(BTLCGD).To efficiently model the complex platform structure,an equivalent single degree of freedom approach was employed.Since the mass contribution of the first mode of the platform is more than 90%,this simplification significantly reduces the computational burden while maintaining accuracy.Therefore,this structure was modeled and analyzed on a scale of 1 to 36 using the Froudian law.To address the limitations of conventional tuned liquid column gas dampers(TLCGDs),which are susceptible to the directionality of seismic excitations,BTLCGD was proposed.This innovative damper is designed to operate effectively in two orthogonal directions,thereby improving seismic performance.Through numerical simulations,the performance of both TLCGD and BTLCGD was evaluated under seismic loading.The results demonstrated that BTLCGD significantly outperforms TLCGD in terms of reducing structural responses,particularly in the direction where TLCGD is ineffective.Furthermore,BTLCGD offers advantages in terms of installation and space requirements.The results of this research offer valuable perspectives into the design and implementation of effective damping systems for offshore structures,contributing to enhanced structural integrity and safety.
基金supported by the National Natural Science Foundation of China(Project Approval Number:52404270)Postdoctoral Innovative Talent Support Program(BX20230427)+2 种基金Postdoctoral Surface Fund Grants(2023M743874)Research Start-up Fund of China University of Petroleum(Beijing)(2462023XKBH017)Fundamental Research Project Grant of China Academy of Safety Science and Technology(2023JBKY07)。
文摘Gas explosions are a frequent hazard in underground confined spaces in the process of urban development.Liquid sedimentary layers,commonly present in these environments,have not been sufficiently studied in terms of their impact on explosion dynamics.This study aims to investigate how gas-liquid two-phase environments in confined underground spaces affect the explosion characteristics of natural gas.To achieve this,experiments are conducted to examine the propagation of natural gas explosions in water and diesel layers,focusing on the influence of liquid properties and the liquid fullness degree(Lx)on explosion behavior.The results indicate that the presence of a liquid layer after the initial ignition stage significantly attenuates both the peak overpressure and the rise speed of pressure,in comparison to the natural gas conditions.During the subsequent explosive reaction,the evaporation and combustion of the diesel surface resulted in a distinct double-peak pressure rise profile in the diesel layer,with the second peak notably exceeding the first peak.Under conditions with a liquid sedimentary layer,the flame propagation velocities range from 6.53 to 34.1 m/s,while the overpressure peaks vary between 0.157 and 0.255 MPa.The explosion duration in both the water and diesel layer environments is approximately twice as long as that of the natural gas explosion,although the underlying mechanisms differ.In the diesel layer,the prolonged explosion time is attributed to the evaporation and combustion of the diesel,while in the water layer,the flame propagation velocity is significantly reduced.Under the experimental conditions,the maximum explosion energy reached 7.15×10~6J,corresponding to a TNT equivalent of 1.7.The peak overpressure surpassed the threshold for human fatality as defined by overpressure standards,posing a potential risk of damage to large steel-frame structures.The explosion shockwave in diesel layer conditions(L_(d)=0%,5%,7.5%,12.5%)and water layer(L_(w)=12.5%)conditions is observed to be sufficient to damage earthquake-resistant reinforced concrete.This study investigates the impact of sediment layer thickness and composition on gas explosions,and evaluates the associated explosion energy to assess human injuries and structural damage in underground environments.The findings of this study provide a scientific reference for urban underground safety.
基金National Natural Science Foundation of China(No.51905089)Fundamental Research Funds for the Central Universities,China(No.2232020D-31)。
文摘The agitated thin-film evaporator(ATFE)plays a crucial role in evaporation and concentration processes.The design of the scraper for processing high-viscosity non-Newtonian fluids in the ATFE is complex.The intricate scraping action of the scraper introduces gas into the liquid film,leading to the formation of a gas ring along the wall.This process subsequently reduces wall heat flow,thereby affecting heat transfer.Computational fluid dynamics(CFD)is used to simulate the flow field of the non-Newtonian fluid in the ATFE.The investigation focuses on understanding the mechanism behind the formation of gas rings in the liquid film and proposes methods to prevent their formation.The results demonstrate a transition of the gas from a gas ring suspended in the liquid to a gas ring attached to the wall after entering the liquid film.The scraping action around the circumference of the scraper helps to expel gas rings,indicating the necessity of adjusting the scraper arrangement and increasing the frequency of scraping to enhance gas ring expulsion.The spiral motion of the bow wave serves as the source of gas entry into the liquid film.Therefore,the rotation speed can appropriately increase to reduce the size of the bow wave,thereby inhibiting the formation of the gas ring from the source.This research investigates the mechanism of gas ring generation and expulsion,offering theoretical guidance for processing high-viscosity non-Newtonian materials in the flow field of the ATFE.
文摘In photothermal power(solar energy)generation systems,purging residual molten salt from pipelines using highpressure gas poses a significant challenge,particularly in clearing the bottom of regulating valves.Ineffective purging can lead to crystallization of the molten salt,resulting in blockages.To address this issue,understanding the gas-liquid two-phase flow dynamics during high-pressure gas purging is crucial.This study utilizes the Volume of Fluid(VOF)model and adaptive dynamic grids to simulate the gas-liquid two-phase flow during the purging process in a DN50 PN50 conventional molten salt regulating valve.Initially,the reliability of the CFD simulations is validated through comparisons with experimental data and findings from the literature.Subsequently,simulation experiments are conducted to analyze the effects of various factors,including purge flow rates,initial liquid accumulation masses,purge durations,and the profiles of the valve bottom flow channels.The results indicate that the purging process comprises four distinct stages:Initial violent surge stage,liquid discharge stage,liquid partial fallback stage,liquid dissipation stage.For an initial liquid height of 17 mm at the bottom of the valve,the critical purge flow rate lies between 3 and 5 m/s.Notably,the critical purge flow rate is independent of the initial liquid accumulation mass.As the purge gas flow rate increases,the volume of liquid discharged also increases.Beyond the critical purge flow rate,higher purge gas velocities lead to shorter purge durations.Interestingly,the residual liquid mass after purging remains unaffected by the initial liquid accumulation.Additionally,the flow channel profile at the bottom of the valve significantly influences both the critical purge speed and the efficiency of the purging process.
文摘In this work,we proposed a strategy for the hydrolysis of native corn starch after the treatment of corn starch in an ionic liquid aqueous solution,and it is an awfully“green”and simple means to obtain starch with low molecular weight and amorphous state.X-ray diffraction results revealed that the natural starch crystalline region was largely disrupted by ionic liquid owing to the broken intermolecular and intramolecular hydrogen bonds.After hydrolysis,the morphology of starch changed from particles of native corn starch into little pieces,and their molecular weight could be effectively regulated during the hydrolysis process,and also the hydrolyzed starch samples exhibited decreased thermal stability with the extension of hydrolysis time.This work would counsel as a powerful tool for the development of native starch in realistic applications.
文摘Designing Fischer-Tropsch synthesis(FTS)catalysts to selectively produce liquid hydrocarbon fuels is a crucial challenge.Herein,we selectively introduced Co nanoparticles(NPs)into the micropores and mesopores of an ordered mesoporous MFI zeolite(OMMZ)through impregnation,which controlled the carbon number distribution in the FTS products by tuning the position of catalytic active sites in differently sized pores.The Co precursors coordinated by acetate with a size of 9.4×4.2×2.5Åand by 2,2'-bipyridine with a size of 9.5×8.7×7.9Å,smaller and larger than the micropores(ca.5.5Å)of MFI,made the Co species incorporated in OMMZ's micropores and mesopores,respectively.The carbon number products synthesized with the Co NPs confined in mesopores were larger than that in micropores.The high jet and diesel selectivities of 66.5%and 65.3%were achieved with Co NPs confined in micropores and mesopores of less acidic Na-type OMMZ,respectively.Gasoline and jet selectivities of 76.7%and 70.8%were achieved with Co NPs confined in micropores and mesopores of H-type OMMZ with Brönsted acid sites,respectively.A series of characterizations revealed that the selective production of diesel and jet fuels was due to the C-C cleavage suppressing of heavier hydrocarbons by the Co NPs located in mesopores.
文摘The Early Eocene Sui Main Limestone(SML)reservoirs in the Qadirpur area are significant hydrocarbon-producing formations but suffer from low permeability and poor reservoir characteristics that lead to well abandonment.Although commonly used,conventional stimulation techniques such as hydraulic fracturing and acidizing pose environmental risks,high costs,and sensitivity to fluctuations in crude oil prices.Meanwhile,cryogenic liquid nitrogen(LN2)treatment has emerged as an innovative,eco-friendly alternative due to its thermal shock effects,which enhance rock permeability and porosity.Herein,SML core samples are treated with LN2 for 30,60,and 90 min to obtain samples designated as SML_30,SML_60,and SML_90,respectively.These are examined using X-ray diffraction(XRD),atomic force microscopy(AFM),scanning electron microscopy(SEM),energy dispersive spectroscopy(EDS),nanoindentation,and petrophysical measurements to evaluate the changes in their petrophysical,morphological,and micromechanical properties.The post-treatment analysis reveals that LN2 cooling effectively induces micro-cracks,with fracture widths of up to 40μm,along with a substantial increase in surface roughness from 350 to 942 nm.Additionally,micromechanical analysis indicates notable changes in the indentation modulus due to stress-induced alterations in the rock matrix.At optimal LN2 exposure(90 min),the porosity and permeability of the SML sample is more than doubled.These findings provide valuable insights into LN2-induced reservoir enhancements,thereby contributing to a better understanding of fluid flow behavior and hydrocarbon recovery in tight gas reservoirs.Thus,LN2 treatment presents a promising,cost-effective,and environmentally sustainable alternative to conventional stimulation methods.
文摘Pediatric cancers are particularly significant due to their uncommon occurrence in children,driven by a variety of underlying factors.Because of their distinct molecular and genetic makeup,which makes early detection challenging,they are linked to problems.Diagnostic methods like imaging and tissue biopsy are only effective when the tumor has reached a size that can be identified.The liquid biopsy technique,the least intrusive and most convenient diagnostic method,is the subject of this review.It focuses on the significance of single cell analysis in examining uncommon cancer types.The many biomarkers found in bodily fluids and the cancer types they are linked to in children have been assessed,as has the potential route towards early detection and cancer recurrence forecasting.Combining the single cell liquid biopsy with the newest technologies,such as computational and multi-omics approaches,which have improved the efficiency of processing massive and unique genetic data,appears promising.This article discusses on a number of case reports for uncommon pediatric malignancies,such as Neuroblastoma,Medulloblastoma,Wilms Tumor,Rhabdomyosarcoma,Ewing Sarcoma,and Retinoblastoma,as well as their liquid biopsy profiles.Furthermore,the findings raise ethical questions regarding the therapeutic application of the technology as well as possible difficulties related to clinical translation.The likelihood that this single cell liquid biopsy will be clinically validated and eventually used as a routine diagnostic tool for uncommon pediatric cancers will rise with the realistic approach to sensitivity monitoring,specificity upgrading,and optimization.
基金supported by National Key Research and Development Program of China(2022YFB3804902,2022YFB3804900)the National Natural Science Foundation of China(52203226,52161145406,42376045)the Fundamental Research Funds for the Central Universities(2232024Y-01,2232025D-02).
文摘While desalination is a key solution for global freshwater scarcity,its implementation faces environmental challenges due to concentrated brine byproducts mainly disposed of via coastal discharge systems.Solar interfacial evaporation offers sustainable management potential,yet inevitable salt nucleation at evaporation interfaces degrades photothermal conversion and operational stability via light scattering and pathway blockage.Inspired by the mangrove leaf,we propose a photothermal 3D polydopamine and polypyrrole polymerized spacer fabric(PPSF)-based upward hanging model evaporation configuration with a reverse water feeding mechanism.This design enables zero-liquiddischarge(ZLD)desalination through phase-separation crystallization.The interconnected porous architecture and the rough surface of the PPSF enable superior water transport,achieving excellent solar-absorbing efficiency of 97.8%.By adjusting the tilt angle(θ),the evaporator separates the evaporation and salt crystallization zones via controlled capillary-driven brine transport,minimizing heat dissipation from brine discharge.At an optimal tilt angle of 52°,the evaporator reaches an evaporation rate of 2.81 kg m^(−2) h^(−1) with minimal heat loss(0.366 W)under 1-sun illumination while treating a 7 wt%waste brine solution.Furthermore,it sustains an evaporation rate of 2.71 kg m^(−2) h^(−1) over 72 h while ensuring efficient salt recovery.These results highlight a scalable,energy-efficient approach for sustainable ZLD desalination.
基金financial support provided by the Natural Science Foundation of Hebei Province,China(No.E2024105036)the Tangshan Talent Funding Project,China(Nos.B202302007 and A2021110015)+1 种基金the National Natural Science Foundation of China(No.52264042)the Australian Research Council(No.IH230100010)。
文摘Automated classification of gas flow states in blast furnaces using top-camera imagery typically demands a large volume of labeled data,whose manual annotation is both labor-intensive and cost-prohibitive.To mitigate this challenge,we present an enhanced semi-supervised learning approach based on the Mean Teacher framework,incorporating a novel feature loss module to maximize classification performance with limited labeled samples.The model studies show that the proposed model surpasses both the baseline Mean Teacher model and fully supervised method in accuracy.Specifically,for datasets with 20%,30%,and 40%label ratios,using a single training iteration,the model yields accuracies of 78.61%,82.21%,and 85.2%,respectively,while multiple-cycle training iterations achieves 82.09%,81.97%,and 81.59%,respectively.Furthermore,scenario-specific training schemes are introduced to support diverse deployment need.These findings highlight the potential of the proposed technique in minimizing labeling requirements and advancing intelligent blast furnace diagnostics.
基金supported by Department of Defense grant HT9425-24-1-0030 a grant from the Stanley Medical Research Institute(to SS).
文摘The inability to access brain tissue has greatly hindered our ability to study and care for individuals suffering from psychiatric and neurological conditions.Critics have questioned efforts to develop peripheral blood biomarkers in neurological and psychiatric disorders based on the assertion that disease pathology is limited to the brain.The discovery that all tissues,including the brain,release extracellular vesicles(Raposo and Stoorvogel,2013)and cell free DNAs(Chan et al.,2013)into various body fluids has provided a potential way to measure activity from inaccessible tissues like the central nervous system(CNS)and has given rise to the term“liquid biopsy.”The development of liquid biopsies that can diagnose and predict the course of psychiatric and neurological disorders would be transformative.The ability to predict episodic events such as mania,depression,and risk for suicide would be particularly useful for psychiatric care as it would enable the development of interventions that prevent mortality and improve outcomes.Additionally,biomarkers that are informative about drug response and aid in treatment decisions would be a significant advance in psychiatric care as it would prevent patients from having to endure multiple courses of ineffective treatments and side effects.
文摘A series of bifunctional catalysts composed of a component for higher alcohol synthesis （Cu-CoMn oxides, CCM） and an acidic zeolite （SAPO-34, ZSM-5, Y, MCM-41） were prepared for production of liquid hydrocarbon directly from a bio-syngas through a one-stage pro-cess. The effects of zeolite type, zeolite content, Si/Al ratio and preparation method on catalyst texture and its reaction performance were investigated. Higher selectivities and yields of liquid products were obtained by using bifunctional catalysts. The yields of liquid hydrocarbons decreased in the order CCM-ZSM-5〉CCM-SAPO-34〉CCM-Y〉CCM-MCM-41. CCM-ZSM-5 （20wt%, Si/Al=100） prepared by coprecipitation method displayed the optimal catalytic performance with the highest CO conversion （76%） and yield of liquid products （30%）. The catalysts were characterized by N2 adsorption/desorption, NH3-TPD, XRD, and H2-TPR analysis. The results showed that higher speci c surface areas and pore volumes of bifunctional catalysts were achieved by adding zeolites into CuCoMn precursors. Medium pore dimension and moderate acidity in CCM-ZSM-5 were observed, which proba-bly resulted in its excellent reaction performance. Additionally, a higher number of weaker acid sites （weak and/or medium acid sites） were formed by increasing ZSM-5 content in CCM-ZSM-5 or decreasing Si/Al ratio in ZSM-5. It was also seen that metal dispersion was higher and reducibility of metal ions was easier on the CCM-ZSM-5 catalyst prepared by coprecipitation. The higher alcohols-to-hydrocarbon process provides a promising route to hydrocarbon fuels via higher alcohols from syngas or biobased feedstocks.
基金ACKNOWLEDGMENTS This work was supported by the Open Project Program of Key Laboratory of Theoretical Chemistry and Molecular Simulation of Ministry of Education, Hunan University of Science and Technology, China （No.E21104）, the National Natural Science Foundation of China （No.21201062 and No.21172066）, and the International Cooperation Project （No.2013DFG60060）.
文摘Quantum mechanics and molecular dynamics are used to simulate guanidinium ionic liquids. Results show that the stronger interaction exists between guanidine cation and chlorine anion with interaction energy about 109.216 kcal/mol. There are two types of spatial distribution for the title system： middle and top. Middle mode is a more stable conformation according to energy and geometric distribution. It is also verified by radial distribution function. The continuous increase of carbon dioxide （CO2） does not affect the structure of ionic liquids, but CO2 molecules are always captured by the cavity of ionic liquids.
基金Project(51271096)supported by the National Natural Science Foundation of ChinaProject(NCET-12-0310)supported by Program for New Century Excellent Talents in University,China
文摘Based on the solid-gas eutectic unidirectional solidification technique and the principle of unidirectional solidification of single-phase alloy, a new method for evaluating the diffusion coefficient of hydrogen in liquid metals was proposed. Taking Cu-H2 system for example, the influences of argon partial pressure and superheat degree of melt on the diffusion coefficient of hydrogen in liquid metal were studied and the predicted values were similar to each other. The obtained temperature-dependent equation for diffusion coefficient of hydrogen in liquid copper is comparable with experimental data in literature, which validates the effectiveness of this method. The temperature-dependent equations for diffusion coefficient of hydrogen in liquid Mg, Si and Cu-34.6%Mn alloy were also evaluated by this method, along with the values at the melting point of each metal and alloy.
基金Supported by the research funds from MIIT program on High Technology Research Program of Ship(2013K4181).
文摘The non-uniformity of gas–liquid mixture is a critical issue which leads to the heat transfer deterioration of spiralwound heat exchangers(SWHEs).Two-phase mass flow rate and the content of gas are important parameters as well as structural parameters which have prominent influences on flow distribution uniformity of SWHE shell side.In order to investigate the influences of these parameters,an experimental test system was built using water and air as mediums and a novel distributor named"tubes distributor"was designed.The effects of mass flow rate and the content of gas on two-phase distribution performance were analyzed,where the mass flow rate ranged from 28.4 to 171.9 kg·h-1 and the content of gas changed from 0.2 to 0.8,respectively.The results showed that the mixture mass flow rate considerably influenced the liquid distribution than that of gas phase and the larger mass flow rate exhibited the better distribution uniformity of two-phase flow.It was also found that the tubes distributor had the better two-phase uniformity when the content of gas was around 0.4.Tube diameter played an important role in the distribution of gas phase and slit width was more significant for the uniformity of liquid phase.
文摘The main intention of the present study is to reduce wind, wave, and seismic induced vibrations of jacket- type offshore wind turbines （JOWTs） through a newly developed vibration absorber, called tuned liquid column gas damper （TLCGD）. Using a Simulink-based model, an analytical model is developed to simulate global behavior of JOWTs under different dynamic excitations. The study is followed by a parametric study to explore efficiency of the TLCGD in terms of nacelle acceleration reduction under wind, wave, and earthquake loads. Study results indicate that optimum frequency of the TLCGD is rather insensitive to excitation type. In addition, while the gain in vibration control from TLCGDs with higher mass ratios is generally more pronounced, heavy TLCGDs are more sensitive to their tuned frequency such that ill-regulated TLCGD with high mass ratio can lead to destructive results. It is revealed that a well regulated TLCGD has noticeable contribution to the dynamic response of the JOWT under any excitation.
文摘The paper introduces gas to liquids (GTL) as a monetising option from a technology, marketing and project perspective. GTL is complementary to LNG and pipelines. At the same time, using natural gas as a source for fuels in the form of GTL helps countries around the world to diversify their energy supplies. Furthermore, gas-based products are inherently cleaner than oil products. Shell's proprietary GTL technology or SMDS (Shell Middle Distillates Synthesis), is discussed in some detail. The paper also covers the challenges for successful implementation of GTL projects and why Shell is well positioned to take a lead in the industry on the basis of its long standing and broad experience in GTL research, plant operations, marketing and excellent track record in mega projects in the last thirty years. Shell's commitment to GTL is best demonstrated by the recent signing of a Heads of Agreement with Qatar Petroleum for the construction of the world's largest GTL plant. A key success factor is Shell's experience with marketing quantities of high quality GTL products from its 12,500 barrels per day plant at Bintulu, Malaysia since 1993. Further marketing opportunities will arise when new GTL capacity comes on-stream in the middle east when more quantities will become available to bulk users. Amongst the most interesting market will be automotive transportation, where clean GTL fuels can be positioned as an 'alternative fuel beyond oil' providing energy security to host countries. Shell is actively engaging with a number of regulators, automotive companies and governments worldwide including China, to demonstrate the performance of GTL and its cost effectiveness in reducing local emissions. An added benefit is that GTL can use existing infrastructure and requires no investment. Finally, the paper briefly discusses the coal to liquids (CTL) process as an alternative route to produce high quality GTL products and the key issues relating to the process.
文摘This paper describes the application of ultrasound waves on hydrodynamics and mass transfer characteristics in the gas–liquid flow in a T-shape microreactor with a diameter of 800 μm. A 1.7 MHz piezoelectric transducer(PZT) was employed to induce the vibration in this microreactor. Liquid side volumetric mass transfer coefficients were measured by physical and chemical methods of CO_2 absorption into water and Na OH solution. The approach of absorption of CO_2 into a 1 mol·L^(-1) Na OH solution was used for analysis of interfacial areas. With the help of a photography system, the fluid flow patterns inside the microreactor were analyzed. The effects of superficial liquid velocity, initial concentration of Na OH, superficial CO_2 gas velocity and length of microreactor on the mass transfer rate were investigated. The comparison between sonicated and plain microreactors(microreactor with and without ultrasound) shows that the ultrasound wave irradiation has a significant effect on kLa and interfacial area at various operational conditions. For the microreactor length of 12 cm, ultrasound waves improved kLa and interfacial area about 21% and 22%, respectively. From this study, it can be concluded that ultrasound wave irradiation in microreactor has a great effect on the mass transfer rate. This study suggests a new enhancement technique to establish high interfacial area and kLa in microreactors.
