Cancers of the lip are the leading cause of labial defects, and treatment is essentially surgical. The success of a repair is assessed by two essential criteria: The functional character of the lip (restoration of con...Cancers of the lip are the leading cause of labial defects, and treatment is essentially surgical. The success of a repair is assessed by two essential criteria: The functional character of the lip (restoration of continence allowing feeding) and the aesthetic quality of the repair. However, for many patients from countries whose medical infrastructure does not allow them to undertake complex reconstructions locally, medical transfers represent their only chance of treatment. The aim of this article is to share with you an extreme clinical case of labial reconstruction, the management of which was a real challenge, using two major flaps: the free ante-brachial flap and the DUFOURMENTEL-type bi-pediculated scalp flap.展开更多
Squamous cell carcinoma (SCC) of the lower lip is a frequently diagnosed malignant pathology in the maxillofacial region. It is a slow-growing cancer, and can be diagnosed and treated easily and effectively;however, e...Squamous cell carcinoma (SCC) of the lower lip is a frequently diagnosed malignant pathology in the maxillofacial region. It is a slow-growing cancer, and can be diagnosed and treated easily and effectively;however, early treatment is important because its mortality rate is 10%-30%. Reconstruction for a large lower lip defect is surgically challenging, especially reconstruction with local flaps. Here, we present a 52-year-old male with a large T3 SCC, which started 13 years before this treatment and involved nearly all of his lower lip, oral commissure and upper lip. It was reconstructed by local flaps with good aesthetic and functional results. The lip was reconstructed with a combination of a Karapandzic flap on one side and a contralateral Webster cheek advancement, using a functional neck dissection on the tumor side and supraomohyoid neck dissection contralaterally. Histopathology results of the neck were negative for metastasis. We were satisfied with the aesthetic and functional results of the neck.展开更多
目的分析1990—2021年中国人群唇和口腔癌发病率的变化趋势、性别和年龄差异,并预测未来发病率的变化趋势,为该疾病防控和公共卫生政策提供科学依据。方法本研究基于全球疾病负担(Global burden of Disease,GBD)数据库1990—2021年中国...目的分析1990—2021年中国人群唇和口腔癌发病率的变化趋势、性别和年龄差异,并预测未来发病率的变化趋势,为该疾病防控和公共卫生政策提供科学依据。方法本研究基于全球疾病负担(Global burden of Disease,GBD)数据库1990—2021年中国人群唇和口腔癌发病率数据,使用Joinpoint回归模型分析时间趋势,采用年龄-时期-队列模型探讨年龄、时期和队列效应对发病率的独立影响,结合贝叶斯年龄-时期-队列模型(Bayesian age-period-cohort model,BAPC)模型预测2022—2044年其发病率的变化趋势。结果1990—2021年,中国唇和口腔癌的标化发病率从2.39/10万上升至3.76/10万,粗发病率从1.71/10万上升至4.85/10万。男性发病率高于女性,且增速更快。年龄效应显示老年人群发病率较高,时期效应揭示2003—2012年间发病率快速增长,队列效应表明早期出生队列的风险较高。BAPC模型预测显示,2022—2044年,中国人群唇和口腔癌的发病率将持续上升。结论中国人群唇和口腔癌发病率呈持续上升趋势,尤其在男性和老年人群中较为突出。未来需加强针对高危人群的筛查和干预。展开更多
文摘Cancers of the lip are the leading cause of labial defects, and treatment is essentially surgical. The success of a repair is assessed by two essential criteria: The functional character of the lip (restoration of continence allowing feeding) and the aesthetic quality of the repair. However, for many patients from countries whose medical infrastructure does not allow them to undertake complex reconstructions locally, medical transfers represent their only chance of treatment. The aim of this article is to share with you an extreme clinical case of labial reconstruction, the management of which was a real challenge, using two major flaps: the free ante-brachial flap and the DUFOURMENTEL-type bi-pediculated scalp flap.
文摘Squamous cell carcinoma (SCC) of the lower lip is a frequently diagnosed malignant pathology in the maxillofacial region. It is a slow-growing cancer, and can be diagnosed and treated easily and effectively;however, early treatment is important because its mortality rate is 10%-30%. Reconstruction for a large lower lip defect is surgically challenging, especially reconstruction with local flaps. Here, we present a 52-year-old male with a large T3 SCC, which started 13 years before this treatment and involved nearly all of his lower lip, oral commissure and upper lip. It was reconstructed by local flaps with good aesthetic and functional results. The lip was reconstructed with a combination of a Karapandzic flap on one side and a contralateral Webster cheek advancement, using a functional neck dissection on the tumor side and supraomohyoid neck dissection contralaterally. Histopathology results of the neck were negative for metastasis. We were satisfied with the aesthetic and functional results of the neck.