BACKGROUND Attention deficit hyperactivity disorder(ADHD)is a prevalent neurodevelopmental disorder in adolescents characterized by inattention,hyperactivity,and impulsivity,which impact cognitive,behavioral,and emoti...BACKGROUND Attention deficit hyperactivity disorder(ADHD)is a prevalent neurodevelopmental disorder in adolescents characterized by inattention,hyperactivity,and impulsivity,which impact cognitive,behavioral,and emotional functioning.Resting-state functional magnetic resonance imaging(rs-fMRI)provides critical insights into the functional architecture of the brain in ADHD.Despite extensive research,specific brain regions consistently affected in ADHD patients during these formative years have not been comprehensively delineated.AIM To identify consistent vulnerable brain regions in adolescent ADHD patients using rs-fMRI and activation likelihood estimation(ALE)meta-analysis.METHODS We conducted a comprehensive literature search up to August 31,2024,to identify studies investigating functional brain alterations in adolescents with ADHD.We utilized regional homogeneity(ReHo),amplitude of low-frequency fluctuations(ALFF),dynamic ALFF(dALFF)and fractional ALFF(fALFF)analyses.We compared the regions of aberrant spontaneous neural activity in adolescents with ADHD with those in healthy controls(HCs)using ALE.RESULTS Fifteen studies(468 adolescent ADHD patients and 466 HCs)were included.Combining the ReHo and ALFF/fALFF/dALFF data,the results revealed increased activity in the right lingual gyrus[LING,Brodmann Area(BA)18],left LING(BA 18),and right cuneus(CUN,BA 23)in adolescent ADHD patients compared with HCs(voxel size:592-32 mm³,P<0.05).Decreased activity was observed in the left medial frontal gyrus(MFG,BA 9)and left precuneus(PCUN,BA 31)in adolescent ADHD patients compared with HCs(voxel size:960-456 mm³,P<0.05).Jackknife sensitivity analyses demonstrated robust reproducibility in 11 of the 13 tests for the right LING,left LING,and right CUN and in 11 of the 14 tests for the left MFG and left PCUN.CONCLUSION We identified specific brain regions with both increased and decreased activity in adolescent ADHD patients,enhancing our understanding of the neural alterations that occur during this pivotal stage of development.展开更多
Over the past few decades, numerous adaptive Kalman filters(AKFs) have been proposed. However, achieving online estimation with both high estimation accuracy and fast convergence speed is challenging, especially when ...Over the past few decades, numerous adaptive Kalman filters(AKFs) have been proposed. However, achieving online estimation with both high estimation accuracy and fast convergence speed is challenging, especially when both the process noise and measurement noise covariance matrices are relatively inaccurate. Maximum likelihood estimation(MLE) possesses the potential to achieve this goal, since its theoretical accuracy is guaranteed by asymptotic optimality and the convergence speed is fast due to weak dependence on accurate state estimation.Unfortunately, the maximum likelihood cost function is so intricate that the existing MLE methods can only simply ignore all historical measurement information to achieve online estimation,which cannot adequately realize the potential of MLE. In order to design online MLE-based AKFs with high estimation accuracy and fast convergence speed, an online exploratory MLE approach is proposed, based on which a mini-batch coordinate descent noise covariance matrix estimation framework is developed. In this framework, the maximum likelihood cost function is simplified for online estimation with fewer and simpler terms which are selected in a mini-batch and calculated with a backtracking method. This maximum likelihood cost function is sidestepped and solved by exploring possible estimated noise covariance matrices adaptively while the historical measurement information is adequately utilized. Furthermore, four specific algorithms are derived under this framework to meet different practical requirements in terms of convergence speed, estimation accuracy,and calculation load. Abundant simulations and experiments are carried out to verify the validity and superiority of the proposed algorithms as compared with existing state-of-the-art AKFs.展开更多
BACKGROUND Major depressive disorder(MDD)in adolescents and young adults contributes significantly to global morbidity,with inconsistent findings on brain structural changes from structural magnetic resonance imaging ...BACKGROUND Major depressive disorder(MDD)in adolescents and young adults contributes significantly to global morbidity,with inconsistent findings on brain structural changes from structural magnetic resonance imaging studies.Activation likeli-hood estimation(ALE)offers a method to synthesize these diverse findings and identify consistent brain anomalies.METHODS We performed a comprehensive literature search in PubMed,Web of Science,Embase,and Chinese National Knowledge Infrastructure databases for neuroi-maging studies on MDD among adolescents and young adults published up to November 19,2023.Two independent researchers performed the study selection,quality assessment,and data extraction.The ALE technique was employed to synthesize findings on localized brain function anomalies in MDD patients,which was supplemented by sensitivity analyses.RESULTS Twenty-two studies comprising fourteen diffusion tensor imaging(DTI)studies and eight voxel-based morphome-try(VBM)studies,and involving 451 MDD patients and 465 healthy controls(HCs)for DTI and 664 MDD patients and 946 HCs for VBM,were included.DTI-based ALE demonstrated significant reductions in fractional anisotropy(FA)values in the right caudate head,right insula,and right lentiform nucleus putamen in adolescents and young adults with MDD compared to HCs,with no regions exhibiting increased FA values.VBM-based ALE did not demonstrate significant alterations in gray matter volume.Sensitivity analyses highlighted consistent findings in the right caudate head(11 of 14 analyses),right insula(10 of 14 analyses),and right lentiform nucleus putamen(11 of 14 analyses).CONCLUSION Structural alterations in the right caudate head,right insula,and right lentiform nucleus putamen in young MDD patients may contribute to its recurrent nature,offering insights for targeted therapies.展开更多
BACKGROUND Adolescent major depressive disorder(MDD)is a significant mental health concern that often leads to recurrent depression in adulthood.Resting-state functional magnetic resonance imaging(rs-fMRI)offers uniqu...BACKGROUND Adolescent major depressive disorder(MDD)is a significant mental health concern that often leads to recurrent depression in adulthood.Resting-state functional magnetic resonance imaging(rs-fMRI)offers unique insights into the neural mechanisms underlying this condition.However,despite previous research,the specific vulnerable brain regions affected in adolescent MDD patients have not been fully elucidated.AIM To identify consistent vulnerable brain regions in adolescent MDD patients using rs-fMRI and activation likelihood estimation(ALE)meta-analysis.METHODS We performed a comprehensive literature search through July 12,2023,for studies investigating brain functional changes in adolescent MDD patients.We utilized regional homogeneity(ReHo),amplitude of low-frequency fluctuations(ALFF)and fractional ALFF(fALFF)analyses.We compared the regions of aberrant spontaneous neural activity in adolescents with MDD vs healthy controls(HCs)using ALE.RESULTS Ten studies(369 adolescent MDD patients and 313 HCs)were included.Combining the ReHo and ALFF/fALFF data,the results revealed that the activity in the right cuneus and left precuneus was lower in the adolescent MDD patients than in the HCs(voxel size:648 mm3,P<0.05),and no brain region exhibited increased activity.Based on the ALFF data,we found decreased activity in the right cuneus and left precuneus in adolescent MDD patients(voxel size:736 mm3,P<0.05),with no regions exhibiting increased activity.CONCLUSION Through ALE meta-analysis,we consistently identified the right cuneus and left precuneus as vulnerable brain regions in adolescent MDD patients,increasing our understanding of the neuropathology of affected adolescents.展开更多
The calibration of transfer functions is essential for accurate pavement performance predictions in the PavementME design. Several studies have used the least square approach to calibrate these transfer functions. Lea...The calibration of transfer functions is essential for accurate pavement performance predictions in the PavementME design. Several studies have used the least square approach to calibrate these transfer functions. Least square is a widely used simplistic approach based on certain assumptions. Literature shows that these least square approach assumptions may not apply to the non-normal distributions. This study introduces a new methodology for calibrating the transverse cracking and international roughness index(IRI) models in rigid pavements using maximum likelihood estimation(MLE). Synthetic data for transverse cracking, with and without variability, are generated to illustrate the applicability of MLE using different known probability distributions(exponential,gamma, log-normal, and negative binomial). The approach uses measured data from the Michigan Department of Transportation's(MDOT) pavement management system(PMS) database for 70 jointed plain concrete pavement(JPCP) sections to calibrate and validate transfer functions. The MLE approach is combined with resampling techniques to improve the robustness of calibration coefficients. The results show that the MLE transverse cracking model using the gamma distribution consistently outperforms the least square for synthetic and observed data. For observed data, MLE estimates of parameters produced lower SSE and bias than least squares(e.g., for the transverse cracking model, the SSE values are 3.98 vs. 4.02, and the bias values are 0.00 and-0.41). Although negative binomial distribution is the most suitable fit for the IRI model for MLE, the least square results are slightly better than MLE. The bias values are-0.312 and 0.000 for the MLE and least square methods. Overall, the findings indicate that MLE is a robust method for calibration, especially for non-normally distributed data such as transverse cracking.展开更多
In order to obtain the life information of the vacuum fluorescent display （VFD） in a short time, a model of constant stress accelerated life tests （CSALT） is established with its filament temperature increased, an...In order to obtain the life information of the vacuum fluorescent display （VFD） in a short time, a model of constant stress accelerated life tests （CSALT） is established with its filament temperature increased, and four constant stress tests are conducted. The Weibull function is applied to describe the life distribution of the VFD, and the maximum likelihood estimation （MLE） and its iterative flow chart are used to calculate the shape parameters and the scale parameters. Furthermore, the accelerated life equation is determined by the least square method, the Kolmogorov-Smirnov test is performed to verify whether the VFD life meets the Weibull distribution or not, and selfdeveloped software is employed to predict the average life and the reliable life. Statistical data analysis results demonstrate that the test plans are feasible and versatile, that the VFD life follows the Weibull distribution, and that the VFD accelerated model satisfies the linear Arrhenius equation. The proposed method and the estimated life information of the VFD can provide some significant guideline to its manufacturers and customers.展开更多
OBJECTIVE: The objective of this study is to summarize and analyze the brain signal patterns of empathy for pain caused by facial expressions of pain utilizing activation likelihood estimation, a meta-analysis method....OBJECTIVE: The objective of this study is to summarize and analyze the brain signal patterns of empathy for pain caused by facial expressions of pain utilizing activation likelihood estimation, a meta-analysis method. DATA SOURCES: Studies concerning the brain mechanism were searched from the Science Citation Index, Science Direct, PubMed, DeepDyve, Cochrane Library, SinoMed, Wanfang, VIP, China National Knowledge Infrastructure, and other databases, such as SpringerLink, AMA, Science Online, Wiley Online, were collected. A time limitation of up to 13 December 2016 was applied to this study. DATA SELECTION: Studies presenting with all of the following criteria were considered for study inclusion: Use of functional magnetic resonance imaging, neutral and pained facial expression stimuli, involvement of adult healthy human participants over 18 years of age, whose empathy ability showed no difference from the healthy adult, a painless basic state, results presented in Talairach or Montreal Neurological Institute coordinates, multiple studies by the same team as long as they used different raw data. OUTCOME MEASURES: Activation likelihood estimation was used to calculate the combined main activated brain regions under the stimulation of pained facial expression. RESULTS: Eight studies were included, containing 178 subjects. Meta-analysis results suggested that the anterior cingulate cortex(BA32), anterior central gyrus(BA44), fusiform gyrus, and insula(BA13) were activated positively as major brain areas under the stimulation of pained facial expression. CONCLUSION: Our study shows that pained facial expression alone, without viewing of painful stimuli, activated brain regions related to pain empathy, further contributing to revealing the brain's mechanisms of pain empathy.展开更多
By taking the subsequence out of the input-output sequence of a system polluted by white noise, an independent observation sequence and its probability density are obtained and then a maximum likelihood estimation of ...By taking the subsequence out of the input-output sequence of a system polluted by white noise, an independent observation sequence and its probability density are obtained and then a maximum likelihood estimation of the identification parameters is given. In order to decrease the asymptotic error, a corrector of maximum likelihood (CML) estimation with its recursive algorithm is given. It has been proved that the corrector has smaller asymptotic error than the least square methods. A simulation example shows that the corrector of maximum likelihood estimation is of higher approximating precision to the true parameters than the least square methods.展开更多
This paper presents a closed-form robust phase correlation based algorithm for performing image registration to subpixel accuracy.The subpixel translational shift information is directly obtained from the phase of the...This paper presents a closed-form robust phase correlation based algorithm for performing image registration to subpixel accuracy.The subpixel translational shift information is directly obtained from the phase of the normalized cross power spectrum by using Maximum Likelihood Estimation(MLE).The proposed algorithm also has slighter time complexity.Experimental results show that the proposed algorithm yields superior registration precision on the Cramér-Rao Bound(CRB) in the presence of aliasing and noise.展开更多
A diagnostic procedure based on maximum likelihood estimation, to study the convergence of the Markov chain produced by Gibbs sampler, is presented. The unbiasedness, consistent and asymptotic normality are considered...A diagnostic procedure based on maximum likelihood estimation, to study the convergence of the Markov chain produced by Gibbs sampler, is presented. The unbiasedness, consistent and asymptotic normality are considered for the estimation of the parameters produced by the procedure. An example is provided to illustrate the procedure, and the numerical result is consistent with the theoretical one.展开更多
Aiming at the solving problem of improved nonhomogeneous Poisson process( NHPP) model in engineering application,the immune clone maximum likelihood estimation( MLE)method for solving model parameters was proposed. Th...Aiming at the solving problem of improved nonhomogeneous Poisson process( NHPP) model in engineering application,the immune clone maximum likelihood estimation( MLE)method for solving model parameters was proposed. The minimum negative log-likelihood function was used as the objective function to optimize instead of using iterative method to solve complex system of equations,and the problem of parameter estimation of improved NHPP model was solved by immune clone algorithm. And the interval estimation of reliability indices was given by using fisher information matrix method and delta method. An example of failure truncated data from multiple numerical control( NC) machine tools was taken to prove the method. and the results show that the algorithm has a higher convergence rate and computational accuracy, which demonstrates the feasibility of the method.展开更多
The Monte Carlo study evaluates the relative accuracy of Warm＇s （1989） weighted likelihood estimate （WLE） compared to the maximum likelihood estimate （MLE） using the nominal response model. And the results indi...The Monte Carlo study evaluates the relative accuracy of Warm＇s （1989） weighted likelihood estimate （WLE） compared to the maximum likelihood estimate （MLE） using the nominal response model. And the results indicate that WLE was more accurate than MLE.展开更多
The performance degradation of an orthogonal frequency division multiplexing (OFDM) systems due to clock synchronization error is analyzed and a pilot-aided maximum likelihood (ML) estimating method is proposed to cor...The performance degradation of an orthogonal frequency division multiplexing (OFDM) systems due to clock synchronization error is analyzed and a pilot-aided maximum likelihood (ML) estimating method is proposed to correct it. The proposed algorithm enables clock synchronization error estimation from a pilot whose duration is only two symbol periods. The study shows that this method is simple and exact. The clock synchronization error can be corrected almost entirely.展开更多
This study addresses the fault detection problem in multi-agent systems(MASs)with additive faults and stochastic uncertainties.The main focus is on enhancing the fault detection capability of each agent through a coop...This study addresses the fault detection problem in multi-agent systems(MASs)with additive faults and stochastic uncertainties.The main focus is on enhancing the fault detection capability of each agent through a cooperative fault detection scheme,fostering cooperation between agents in two scenarios.For Gaussian uncertainties,one scheme is developed using the maximum likelihood estimation(MLE)matching expectation maximization(EM)algorithm.Additionally,a novel cooperative fault detection scheme is introduced to handle non-Gaussian uncertainties,where the cooperation mechanism among agents is determined by approximating non-Gaussian uncertainties using the Gaussian mixture model(GMM).The effectiveness and improvements of the proposed cooperative fault detection method are validated through numerical simulations.展开更多
Blade Tip Timing(BTT)enables non-contact measurements of rotating blades by placing probes strategically.Due to the uneven probe layout,BTT signals exhibit periodic irregularities.While recovering parameters like freq...Blade Tip Timing(BTT)enables non-contact measurements of rotating blades by placing probes strategically.Due to the uneven probe layout,BTT signals exhibit periodic irregularities.While recovering parameters like frequency from such signals is possible,achieving high-precision vibration parameters remains challenging.This paper proposed a novel two-stage off-grid estimation method.It leverages a unique array layout(coprime array)to obtain a regular augmented covariance matrix.Subsequently,parameters in the matrix are recovered using the sparse iterative covariance-based estimation method based on covariance fitting criteria.Finally,high-precision estimates of imprecise parameters are obtained using unconditional maximum likelihood estimation,effectively eliminating the effects of basis mismatch.Through substantial numerical and experimental validation,the proposed method demonstrates significantly higher accuracy compared to classical BTT parameter estimation methods,approaching the lower bound of unbiased estimation variance.Furthermore,due to its immunity to frequency gridding,it can track minor frequency deviations,making it more suitable for indicating blade condition.展开更多
The existence and uniqueness of the maximum likelihood estimator(MLE)of parameter for the exponential-Poisson distribution is discussed by Ku s[2007.A new lifetime distribution.Computational Statistics and Data Analys...The existence and uniqueness of the maximum likelihood estimator(MLE)of parameter for the exponential-Poisson distribution is discussed by Ku s[2007.A new lifetime distribution.Computational Statistics and Data Analysis 51(9):4497-4509]in simple random sampling(SRS).As an alternative to the MLEs in SRS,Joukar et al.[2021.Parameter estimation for the exponential-poisson distribution based on ranked set samples.Communication in Statistics-Theory and Methods 50(3):560-581]discussed the MLE of parameter for this distribution in ranked set sampling(RSS).However,they did not discuss the existence and uniqueness of the MLE in RSS and did not provide explicit expressions for the Fisher information in RSS.In this article,we discuss the existence and uniqueness of the MLE of parameter in RSS and give explicit expressions for the Fisher information in RSS.The MLEs will be compared in terms of asymptotic efficiencies.Numerical studies and a real data application show that these MLEs in RSS can be real competitors for those in SRS.展开更多
Background：Several studies using functional magnetic resonance imaging （fMRI） and positron emission tomography （PET） have indicated that cognitive remediation therapy （CRT） might improve cognitive function by c...Background：Several studies using functional magnetic resonance imaging （fMRI） and positron emission tomography （PET） have indicated that cognitive remediation therapy （CRT） might improve cognitive function by changing brain activations in patients with schizophrenia.However,the results were not consistent in these changed brain areas in different studies.The present activation likelihood estimation （ALE） meta-analysis was conducted to investigate whether cognitive function change was accompanied by the brain activation changes,and where the main areas most related to these changes were in schizophrenia patients after CRT.Analyses of whole-brain studies and whole-brain ＋ region of interest （ROI） studies were compared to explore the effect of the different methodologies on the results.Methods：A computerized systematic search was conducted to collect fMRI and PET studies on brain activation changes in schizophrenia patients from pre-to post-CRT.Nine studies using fMRI techniques were included in the meta-analysis.Ginger ALE 2.3.1 was used to perform meta-analysis across these imaging studies.Results：The main areas with increased brain activation were in frontal and parietal lobe,including left medial frontal gyrus,left inferior frontal gyrus,right middle frontal gyrus,right postcentral gyrus,and inferior parietal lobule in patients after CRT,yet no decreased brain activation was found.Although similar increased activation brain areas were identified in ALE with or without ROI studies,analysis including ROI studies had a higher ALE value.Conclusions：The current findings suggest that CRT might improve the cognition of schizophrenia patients by increasing activations of the frontal and parietal lobe.In addition,it might provide more evidence to confirm results by including ROI studies in ALE meta-analysis.展开更多
To estimate the spreading sequence of the direct sequence spread spectrum (DSSS) signal, a fast algorithm based on maximum likelihood function is proposed, and the theoretical derivation of the algorithm is provided. ...To estimate the spreading sequence of the direct sequence spread spectrum (DSSS) signal, a fast algorithm based on maximum likelihood function is proposed, and the theoretical derivation of the algorithm is provided. By simplifying the objective function of maximum likelihood estimation, the algorithm can realize sequence synchronization and sequence estimation via adaptive iteration and sliding window. Since it avoids the correlation matrix computation, the algorithm significantly reduces the storage requirement and the computation complexity. Simulations show that it is a fast convergent algorithm, and can perform well in low signal to noise ratio (SNR).展开更多
Traditional frame synchronization methods for underwater acoustic communication(UWAC) merely depend on correlation coefficient when synchronization signal detection is concerned and,hence,false triggering and missed s...Traditional frame synchronization methods for underwater acoustic communication(UWAC) merely depend on correlation coefficient when synchronization signal detection is concerned and,hence,false triggering and missed synchronization can hardly be avoided in complex UWAC channels.In order to solve this problem,firstly,we analyze the effects of interference from noise,multipath and Doppler on frame synchronization;then we propose a new frame synchronization scheme based on parameter estimation.By exploiting the parameter estimation technique,we detect the synchronization signal according to the estimated parameters,thus the false triggering rate and missed synchronization rate can be reduced.We also simplify the maximum likelihood estimation to reduce computational cost.Simulation results indicate that this new scheme outperforms the traditional method in terms of delay resolution and correlation coefficient.Both static and mobile communication experimental results show that the correlation coefficient of the new scheme is higher than that of the traditional one.Moreover,the detection ability of the receiver is improved,which helps to avoid false triggering and missed synchronization.展开更多
To break through the limitations of traditional discriminators used in vector tracking loops, this paper presents an iterative maximum likelihood estimation(IMLE) method for extracting navigation state errors from mul...To break through the limitations of traditional discriminators used in vector tracking loops, this paper presents an iterative maximum likelihood estimation(IMLE) method for extracting navigation state errors from multi-satellite signals. The IMLE method takes into account both computational cost and estimation accuracy. The associated gradient vector and Hessian matrix of the MLE cost function are derived. The characteristics of the proposed joint discriminator are analyzed based on the properties of the MLE cost function,gradient vector, and Hessian matrix. The effectiveness of IMLE is verified by Monte Carlo simulation.展开更多
基金Supported by National Natural Science Foundation of China,No.82460282Guizhou Province Science and Technology Plan Project,No.ZK-2023-195+1 种基金Guizhou High-Level Innovative Talent Project,No.gzwjrs2022-013Health Commission of Guizhou Province Project,No.gzwkj2024-475 and No.gzwkj2021-150.
文摘BACKGROUND Attention deficit hyperactivity disorder(ADHD)is a prevalent neurodevelopmental disorder in adolescents characterized by inattention,hyperactivity,and impulsivity,which impact cognitive,behavioral,and emotional functioning.Resting-state functional magnetic resonance imaging(rs-fMRI)provides critical insights into the functional architecture of the brain in ADHD.Despite extensive research,specific brain regions consistently affected in ADHD patients during these formative years have not been comprehensively delineated.AIM To identify consistent vulnerable brain regions in adolescent ADHD patients using rs-fMRI and activation likelihood estimation(ALE)meta-analysis.METHODS We conducted a comprehensive literature search up to August 31,2024,to identify studies investigating functional brain alterations in adolescents with ADHD.We utilized regional homogeneity(ReHo),amplitude of low-frequency fluctuations(ALFF),dynamic ALFF(dALFF)and fractional ALFF(fALFF)analyses.We compared the regions of aberrant spontaneous neural activity in adolescents with ADHD with those in healthy controls(HCs)using ALE.RESULTS Fifteen studies(468 adolescent ADHD patients and 466 HCs)were included.Combining the ReHo and ALFF/fALFF/dALFF data,the results revealed increased activity in the right lingual gyrus[LING,Brodmann Area(BA)18],left LING(BA 18),and right cuneus(CUN,BA 23)in adolescent ADHD patients compared with HCs(voxel size:592-32 mm³,P<0.05).Decreased activity was observed in the left medial frontal gyrus(MFG,BA 9)and left precuneus(PCUN,BA 31)in adolescent ADHD patients compared with HCs(voxel size:960-456 mm³,P<0.05).Jackknife sensitivity analyses demonstrated robust reproducibility in 11 of the 13 tests for the right LING,left LING,and right CUN and in 11 of the 14 tests for the left MFG and left PCUN.CONCLUSION We identified specific brain regions with both increased and decreased activity in adolescent ADHD patients,enhancing our understanding of the neural alterations that occur during this pivotal stage of development.
基金supported in part by the National Key Research and Development Program of China(2023YFB3906403)the National Natural Science Foundation of China(62373118,62173105)the Natural Science Foundation of Heilongjiang Province of China(ZD2023F002)
文摘Over the past few decades, numerous adaptive Kalman filters(AKFs) have been proposed. However, achieving online estimation with both high estimation accuracy and fast convergence speed is challenging, especially when both the process noise and measurement noise covariance matrices are relatively inaccurate. Maximum likelihood estimation(MLE) possesses the potential to achieve this goal, since its theoretical accuracy is guaranteed by asymptotic optimality and the convergence speed is fast due to weak dependence on accurate state estimation.Unfortunately, the maximum likelihood cost function is so intricate that the existing MLE methods can only simply ignore all historical measurement information to achieve online estimation,which cannot adequately realize the potential of MLE. In order to design online MLE-based AKFs with high estimation accuracy and fast convergence speed, an online exploratory MLE approach is proposed, based on which a mini-batch coordinate descent noise covariance matrix estimation framework is developed. In this framework, the maximum likelihood cost function is simplified for online estimation with fewer and simpler terms which are selected in a mini-batch and calculated with a backtracking method. This maximum likelihood cost function is sidestepped and solved by exploring possible estimated noise covariance matrices adaptively while the historical measurement information is adequately utilized. Furthermore, four specific algorithms are derived under this framework to meet different practical requirements in terms of convergence speed, estimation accuracy,and calculation load. Abundant simulations and experiments are carried out to verify the validity and superiority of the proposed algorithms as compared with existing state-of-the-art AKFs.
基金Supported by the Guizhou Province Science and Technology Plan Project,No.ZK-2023-1952021 Health Commission of Guizhou Province Project,No.gzwkj2021-150.
文摘BACKGROUND Major depressive disorder(MDD)in adolescents and young adults contributes significantly to global morbidity,with inconsistent findings on brain structural changes from structural magnetic resonance imaging studies.Activation likeli-hood estimation(ALE)offers a method to synthesize these diverse findings and identify consistent brain anomalies.METHODS We performed a comprehensive literature search in PubMed,Web of Science,Embase,and Chinese National Knowledge Infrastructure databases for neuroi-maging studies on MDD among adolescents and young adults published up to November 19,2023.Two independent researchers performed the study selection,quality assessment,and data extraction.The ALE technique was employed to synthesize findings on localized brain function anomalies in MDD patients,which was supplemented by sensitivity analyses.RESULTS Twenty-two studies comprising fourteen diffusion tensor imaging(DTI)studies and eight voxel-based morphome-try(VBM)studies,and involving 451 MDD patients and 465 healthy controls(HCs)for DTI and 664 MDD patients and 946 HCs for VBM,were included.DTI-based ALE demonstrated significant reductions in fractional anisotropy(FA)values in the right caudate head,right insula,and right lentiform nucleus putamen in adolescents and young adults with MDD compared to HCs,with no regions exhibiting increased FA values.VBM-based ALE did not demonstrate significant alterations in gray matter volume.Sensitivity analyses highlighted consistent findings in the right caudate head(11 of 14 analyses),right insula(10 of 14 analyses),and right lentiform nucleus putamen(11 of 14 analyses).CONCLUSION Structural alterations in the right caudate head,right insula,and right lentiform nucleus putamen in young MDD patients may contribute to its recurrent nature,offering insights for targeted therapies.
基金Supported by The 2024 Guizhou Provincial Health Commission Science and Technology Fund Project,No.gzwkj2024-47502022 Provincial Clinical Key Specialty Construction Project。
文摘BACKGROUND Adolescent major depressive disorder(MDD)is a significant mental health concern that often leads to recurrent depression in adulthood.Resting-state functional magnetic resonance imaging(rs-fMRI)offers unique insights into the neural mechanisms underlying this condition.However,despite previous research,the specific vulnerable brain regions affected in adolescent MDD patients have not been fully elucidated.AIM To identify consistent vulnerable brain regions in adolescent MDD patients using rs-fMRI and activation likelihood estimation(ALE)meta-analysis.METHODS We performed a comprehensive literature search through July 12,2023,for studies investigating brain functional changes in adolescent MDD patients.We utilized regional homogeneity(ReHo),amplitude of low-frequency fluctuations(ALFF)and fractional ALFF(fALFF)analyses.We compared the regions of aberrant spontaneous neural activity in adolescents with MDD vs healthy controls(HCs)using ALE.RESULTS Ten studies(369 adolescent MDD patients and 313 HCs)were included.Combining the ReHo and ALFF/fALFF data,the results revealed that the activity in the right cuneus and left precuneus was lower in the adolescent MDD patients than in the HCs(voxel size:648 mm3,P<0.05),and no brain region exhibited increased activity.Based on the ALFF data,we found decreased activity in the right cuneus and left precuneus in adolescent MDD patients(voxel size:736 mm3,P<0.05),with no regions exhibiting increased activity.CONCLUSION Through ALE meta-analysis,we consistently identified the right cuneus and left precuneus as vulnerable brain regions in adolescent MDD patients,increasing our understanding of the neuropathology of affected adolescents.
基金the Michigan Department of Transportation (MDOT) for the financial support of this study (report no. SPR1723)。
文摘The calibration of transfer functions is essential for accurate pavement performance predictions in the PavementME design. Several studies have used the least square approach to calibrate these transfer functions. Least square is a widely used simplistic approach based on certain assumptions. Literature shows that these least square approach assumptions may not apply to the non-normal distributions. This study introduces a new methodology for calibrating the transverse cracking and international roughness index(IRI) models in rigid pavements using maximum likelihood estimation(MLE). Synthetic data for transverse cracking, with and without variability, are generated to illustrate the applicability of MLE using different known probability distributions(exponential,gamma, log-normal, and negative binomial). The approach uses measured data from the Michigan Department of Transportation's(MDOT) pavement management system(PMS) database for 70 jointed plain concrete pavement(JPCP) sections to calibrate and validate transfer functions. The MLE approach is combined with resampling techniques to improve the robustness of calibration coefficients. The results show that the MLE transverse cracking model using the gamma distribution consistently outperforms the least square for synthetic and observed data. For observed data, MLE estimates of parameters produced lower SSE and bias than least squares(e.g., for the transverse cracking model, the SSE values are 3.98 vs. 4.02, and the bias values are 0.00 and-0.41). Although negative binomial distribution is the most suitable fit for the IRI model for MLE, the least square results are slightly better than MLE. The bias values are-0.312 and 0.000 for the MLE and least square methods. Overall, the findings indicate that MLE is a robust method for calibration, especially for non-normally distributed data such as transverse cracking.
基金Undergraduate Education High land Construction Project of Shanghaithe Key Course Construction of Shanghai Education Committee (No.20075302)the Key Technology R&D Program of Shanghai Municipality (No.08160510600)
文摘In order to obtain the life information of the vacuum fluorescent display （VFD） in a short time, a model of constant stress accelerated life tests （CSALT） is established with its filament temperature increased, and four constant stress tests are conducted. The Weibull function is applied to describe the life distribution of the VFD, and the maximum likelihood estimation （MLE） and its iterative flow chart are used to calculate the shape parameters and the scale parameters. Furthermore, the accelerated life equation is determined by the least square method, the Kolmogorov-Smirnov test is performed to verify whether the VFD life meets the Weibull distribution or not, and selfdeveloped software is employed to predict the average life and the reliable life. Statistical data analysis results demonstrate that the test plans are feasible and versatile, that the VFD life follows the Weibull distribution, and that the VFD accelerated model satisfies the linear Arrhenius equation. The proposed method and the estimated life information of the VFD can provide some significant guideline to its manufacturers and customers.
基金supported by the National Natural Science Foundation of China,No.81473769(to WW),81772430(to WW)a grant from the Training Program of Innovation and Entrepreneurship for Undergraduates of Southern Medical University of Guangdong Province of China in 2016,No.201612121057(to WW)
文摘OBJECTIVE: The objective of this study is to summarize and analyze the brain signal patterns of empathy for pain caused by facial expressions of pain utilizing activation likelihood estimation, a meta-analysis method. DATA SOURCES: Studies concerning the brain mechanism were searched from the Science Citation Index, Science Direct, PubMed, DeepDyve, Cochrane Library, SinoMed, Wanfang, VIP, China National Knowledge Infrastructure, and other databases, such as SpringerLink, AMA, Science Online, Wiley Online, were collected. A time limitation of up to 13 December 2016 was applied to this study. DATA SELECTION: Studies presenting with all of the following criteria were considered for study inclusion: Use of functional magnetic resonance imaging, neutral and pained facial expression stimuli, involvement of adult healthy human participants over 18 years of age, whose empathy ability showed no difference from the healthy adult, a painless basic state, results presented in Talairach or Montreal Neurological Institute coordinates, multiple studies by the same team as long as they used different raw data. OUTCOME MEASURES: Activation likelihood estimation was used to calculate the combined main activated brain regions under the stimulation of pained facial expression. RESULTS: Eight studies were included, containing 178 subjects. Meta-analysis results suggested that the anterior cingulate cortex(BA32), anterior central gyrus(BA44), fusiform gyrus, and insula(BA13) were activated positively as major brain areas under the stimulation of pained facial expression. CONCLUSION: Our study shows that pained facial expression alone, without viewing of painful stimuli, activated brain regions related to pain empathy, further contributing to revealing the brain's mechanisms of pain empathy.
文摘By taking the subsequence out of the input-output sequence of a system polluted by white noise, an independent observation sequence and its probability density are obtained and then a maximum likelihood estimation of the identification parameters is given. In order to decrease the asymptotic error, a corrector of maximum likelihood (CML) estimation with its recursive algorithm is given. It has been proved that the corrector has smaller asymptotic error than the least square methods. A simulation example shows that the corrector of maximum likelihood estimation is of higher approximating precision to the true parameters than the least square methods.
文摘This paper presents a closed-form robust phase correlation based algorithm for performing image registration to subpixel accuracy.The subpixel translational shift information is directly obtained from the phase of the normalized cross power spectrum by using Maximum Likelihood Estimation(MLE).The proposed algorithm also has slighter time complexity.Experimental results show that the proposed algorithm yields superior registration precision on the Cramér-Rao Bound(CRB) in the presence of aliasing and noise.
文摘A diagnostic procedure based on maximum likelihood estimation, to study the convergence of the Markov chain produced by Gibbs sampler, is presented. The unbiasedness, consistent and asymptotic normality are considered for the estimation of the parameters produced by the procedure. An example is provided to illustrate the procedure, and the numerical result is consistent with the theoretical one.
基金National CNC Special Project,China(No.2010ZX04001-032)the Youth Science and Technology Foundation of Gansu Province,China(No.145RJYA307)
文摘Aiming at the solving problem of improved nonhomogeneous Poisson process( NHPP) model in engineering application,the immune clone maximum likelihood estimation( MLE)method for solving model parameters was proposed. The minimum negative log-likelihood function was used as the objective function to optimize instead of using iterative method to solve complex system of equations,and the problem of parameter estimation of improved NHPP model was solved by immune clone algorithm. And the interval estimation of reliability indices was given by using fisher information matrix method and delta method. An example of failure truncated data from multiple numerical control( NC) machine tools was taken to prove the method. and the results show that the algorithm has a higher convergence rate and computational accuracy, which demonstrates the feasibility of the method.
文摘The Monte Carlo study evaluates the relative accuracy of Warm＇s （1989） weighted likelihood estimate （WLE） compared to the maximum likelihood estimate （MLE） using the nominal response model. And the results indicate that WLE was more accurate than MLE.
文摘The performance degradation of an orthogonal frequency division multiplexing (OFDM) systems due to clock synchronization error is analyzed and a pilot-aided maximum likelihood (ML) estimating method is proposed to correct it. The proposed algorithm enables clock synchronization error estimation from a pilot whose duration is only two symbol periods. The study shows that this method is simple and exact. The clock synchronization error can be corrected almost entirely.
基金supported in part by the National Natural Science Foundation of China under Grant Nos.62103304 and 62177036Shanghai Sailing Program under Grant No.21YF1450500+1 种基金Shanghai Municipal Science and Technology Major Project under Grant No.2021SHZDZX0100Shanghai Municipal Commission of Science and Technology Project under Grant No.19511132101。
文摘This study addresses the fault detection problem in multi-agent systems(MASs)with additive faults and stochastic uncertainties.The main focus is on enhancing the fault detection capability of each agent through a cooperative fault detection scheme,fostering cooperation between agents in two scenarios.For Gaussian uncertainties,one scheme is developed using the maximum likelihood estimation(MLE)matching expectation maximization(EM)algorithm.Additionally,a novel cooperative fault detection scheme is introduced to handle non-Gaussian uncertainties,where the cooperation mechanism among agents is determined by approximating non-Gaussian uncertainties using the Gaussian mixture model(GMM).The effectiveness and improvements of the proposed cooperative fault detection method are validated through numerical simulations.
基金the National Natural Science Foundation of China(Nos.52105117,52222504&51875433)the Funds for Distinguished Young talent of Shaanxi Province,China(No.2019JC-04)。
文摘Blade Tip Timing(BTT)enables non-contact measurements of rotating blades by placing probes strategically.Due to the uneven probe layout,BTT signals exhibit periodic irregularities.While recovering parameters like frequency from such signals is possible,achieving high-precision vibration parameters remains challenging.This paper proposed a novel two-stage off-grid estimation method.It leverages a unique array layout(coprime array)to obtain a regular augmented covariance matrix.Subsequently,parameters in the matrix are recovered using the sparse iterative covariance-based estimation method based on covariance fitting criteria.Finally,high-precision estimates of imprecise parameters are obtained using unconditional maximum likelihood estimation,effectively eliminating the effects of basis mismatch.Through substantial numerical and experimental validation,the proposed method demonstrates significantly higher accuracy compared to classical BTT parameter estimation methods,approaching the lower bound of unbiased estimation variance.Furthermore,due to its immunity to frequency gridding,it can track minor frequency deviations,making it more suitable for indicating blade condition.
基金Supported by the National Natural Science Foundation of China(11901236,12261036)Scientific Research Fund of Hunan Provincial Education Department(21A0328)Young Core Teacher Foundation of Hunan Province([2020]43).
文摘The existence and uniqueness of the maximum likelihood estimator(MLE)of parameter for the exponential-Poisson distribution is discussed by Ku s[2007.A new lifetime distribution.Computational Statistics and Data Analysis 51(9):4497-4509]in simple random sampling(SRS).As an alternative to the MLEs in SRS,Joukar et al.[2021.Parameter estimation for the exponential-poisson distribution based on ranked set samples.Communication in Statistics-Theory and Methods 50(3):560-581]discussed the MLE of parameter for this distribution in ranked set sampling(RSS).However,they did not discuss the existence and uniqueness of the MLE in RSS and did not provide explicit expressions for the Fisher information in RSS.In this article,we discuss the existence and uniqueness of the MLE of parameter in RSS and give explicit expressions for the Fisher information in RSS.The MLEs will be compared in terms of asymptotic efficiencies.Numerical studies and a real data application show that these MLEs in RSS can be real competitors for those in SRS.
基金This study was supported by the grants from the National Nature Science Foundation of China
文摘Background：Several studies using functional magnetic resonance imaging （fMRI） and positron emission tomography （PET） have indicated that cognitive remediation therapy （CRT） might improve cognitive function by changing brain activations in patients with schizophrenia.However,the results were not consistent in these changed brain areas in different studies.The present activation likelihood estimation （ALE） meta-analysis was conducted to investigate whether cognitive function change was accompanied by the brain activation changes,and where the main areas most related to these changes were in schizophrenia patients after CRT.Analyses of whole-brain studies and whole-brain ＋ region of interest （ROI） studies were compared to explore the effect of the different methodologies on the results.Methods：A computerized systematic search was conducted to collect fMRI and PET studies on brain activation changes in schizophrenia patients from pre-to post-CRT.Nine studies using fMRI techniques were included in the meta-analysis.Ginger ALE 2.3.1 was used to perform meta-analysis across these imaging studies.Results：The main areas with increased brain activation were in frontal and parietal lobe,including left medial frontal gyrus,left inferior frontal gyrus,right middle frontal gyrus,right postcentral gyrus,and inferior parietal lobule in patients after CRT,yet no decreased brain activation was found.Although similar increased activation brain areas were identified in ALE with or without ROI studies,analysis including ROI studies had a higher ALE value.Conclusions：The current findings suggest that CRT might improve the cognition of schizophrenia patients by increasing activations of the frontal and parietal lobe.In addition,it might provide more evidence to confirm results by including ROI studies in ALE meta-analysis.
基金supported by Joint Foundation of and China Academy of Engineering Physical (10676006)
文摘To estimate the spreading sequence of the direct sequence spread spectrum (DSSS) signal, a fast algorithm based on maximum likelihood function is proposed, and the theoretical derivation of the algorithm is provided. By simplifying the objective function of maximum likelihood estimation, the algorithm can realize sequence synchronization and sequence estimation via adaptive iteration and sliding window. Since it avoids the correlation matrix computation, the algorithm significantly reduces the storage requirement and the computation complexity. Simulations show that it is a fast convergent algorithm, and can perform well in low signal to noise ratio (SNR).
基金supported by the National Natural Science Foundation of China(61431020)
文摘Traditional frame synchronization methods for underwater acoustic communication(UWAC) merely depend on correlation coefficient when synchronization signal detection is concerned and,hence,false triggering and missed synchronization can hardly be avoided in complex UWAC channels.In order to solve this problem,firstly,we analyze the effects of interference from noise,multipath and Doppler on frame synchronization;then we propose a new frame synchronization scheme based on parameter estimation.By exploiting the parameter estimation technique,we detect the synchronization signal according to the estimated parameters,thus the false triggering rate and missed synchronization rate can be reduced.We also simplify the maximum likelihood estimation to reduce computational cost.Simulation results indicate that this new scheme outperforms the traditional method in terms of delay resolution and correlation coefficient.Both static and mobile communication experimental results show that the correlation coefficient of the new scheme is higher than that of the traditional one.Moreover,the detection ability of the receiver is improved,which helps to avoid false triggering and missed synchronization.
基金supported by National High Technology Research and Development Program of China(863)(Grant No.2013AA1548)
文摘To break through the limitations of traditional discriminators used in vector tracking loops, this paper presents an iterative maximum likelihood estimation(IMLE) method for extracting navigation state errors from multi-satellite signals. The IMLE method takes into account both computational cost and estimation accuracy. The associated gradient vector and Hessian matrix of the MLE cost function are derived. The characteristics of the proposed joint discriminator are analyzed based on the properties of the MLE cost function,gradient vector, and Hessian matrix. The effectiveness of IMLE is verified by Monte Carlo simulation.
