Facial sagging is a major aging change that affects the overall shape of the face. Sagging can negatively impact self-perception and consequently quality of life. In order to fight against this aging sign, we develope...Facial sagging is a major aging change that affects the overall shape of the face. Sagging can negatively impact self-perception and consequently quality of life. In order to fight against this aging sign, we developed a combination of three active ingredients: Tetrahydroxypropyl Ethylenediamine (THPE), Ononis Spinosa extract and Glycerin. In a clinical study, we assessed the efficacy of this association on facial sagging and wrinkles, with a special focus on immediate and lasting effects. Thirty-nine women applied the tested product daily during an eight-week treatment period. Clinical grading by experts and a new, easy to operate, 2-D imaging method were performed at different time points. The 2-D imaging method measured the upper eyelid lifting effect. The results showed an immediate and significant improvement in sagging and wrinkle parameters;these benefits were still observed seven hours after the first application. Results also showed a significant long-term improvement. The lifting effect calculated from the 2-D pictures was 1.08 mm immediately after application;the same method showed a 1.80 mm lifting effect following the eight-week treatment period. These results suggest that a skin care product combining THPE, Ononis Spinosa and Glycerin properties may be used to reduce sagging as well as wrinkles with both immediate and long term benefits.展开更多
目的比较改良LIFT术与切开挂线引流术治疗复杂性肛瘘的临床疗效。方法选取本院收治的复杂性肛瘘患者108例,其中观察组54例采用改良LIFT术,对照组54例采用传统切开挂线引流术,比较两组疗效、疾病恢复、并发症和复发率等指标。结果观察组...目的比较改良LIFT术与切开挂线引流术治疗复杂性肛瘘的临床疗效。方法选取本院收治的复杂性肛瘘患者108例,其中观察组54例采用改良LIFT术,对照组54例采用传统切开挂线引流术,比较两组疗效、疾病恢复、并发症和复发率等指标。结果观察组治疗总有效率(98.15%)与对照组治疗总有效率(92.59%)比较差异不显著(P>0.05);观察组住院时间、切口愈合时间、切口愈合面积、愈后Wexner评分、术后7 d VAS评分均优于对照组(P<0.05);两组并发症发生率和复发率比较差异不显著(P>0.05)。结论相对于切开挂线引流术,改良LIFT术治疗复杂性肛瘘可有效缩短患者住院和切口愈合时间,减轻术后疼痛,并较好保留肛门功能。展开更多
Numerical simulations are carried out for wave action on a submerged horizontal circular cylinder by means of a viscous fluid model, and it is focused on the examination of the discrepancies between the viscous fluid ...Numerical simulations are carried out for wave action on a submerged horizontal circular cylinder by means of a viscous fluid model, and it is focused on the examination of the discrepancies between the viscous fluid results and the potential flow solutions. It is found that the lift force resulted from rotational flow on the circular cylinder is always in anti-phase with the inertia force and induces the discrepancies between the results. The influence factors on the magnitude of the lift force, especially the correlation between the stagnation-point position and the wave amplitude, and the effect of the vortex shedding are investigated by further examination on the flow fields around the cylinder. The viscous numerical calculations at different wave frequencies showed that the wave frequency has also significant influence on the wave forces. Under higher frequency and larger amplitude wave action, vortex shedding from the circular cylinder will appear and influence the wave forces on the cylinder substantially.展开更多
Computational simulations of aerodynamic characteristics of the Common Research Model (CRM), representing a typical transport airliner are conducted using CFD methods in close proximity to the ground. The obtained dep...Computational simulations of aerodynamic characteristics of the Common Research Model (CRM), representing a typical transport airliner are conducted using CFD methods in close proximity to the ground. The obtained dependencies on bank angle for aerodynamic forces and moments are further used in stability and controllability analysis of the lateral-directional aircraft motion. Essential changes in the lateral-directional modes in close proximity to the ground have been identified. For example, with approach to the ground, the roll subsidence and spiral eigenvalues are merging creating the oscillatory Roll-Spiral mode with quite significant frequency. This transformation of the lateral-directional dynamics in piloted simulation may affect the aircraft responses to external crosswind, modify handling quality characteristics and improve realism of crosswind landing. The material of this paper was presented at the Seventh European Conference for Aeronautics and Space Sciences EUCASS-2017. Further work is carried out for evaluation of the ground effect aerodynamics for a high-lift configuration based on a hybrid geometry of DLR F11 and NASA GTM models with fully deployed flaps and slats. Some aspects of grid generation for a high lift configuration using structured blocking approach are discussed.展开更多
Computational prediction of stall aerodynamics in free air and in close proximity to the ground considering the 30P30N three-element high-lift configuration is carried out based on CFD simulations using the OpenFOAM c...Computational prediction of stall aerodynamics in free air and in close proximity to the ground considering the 30P30N three-element high-lift configuration is carried out based on CFD simulations using the OpenFOAM code and Fluent software. Both the attached and separated flow regimes are simulated using the Reynolds Averaged Navier-Stokes (RANS) equations closed with the Spalart-Allamaras (SA) turbulence model for static conditions and pitch oscillations at Reynolds number, <em>Re</em> = 5 x 10<sup>6</sup> and Mach number, <em>M</em> = 0.2. The effects of closeness to the ground and dynamic stall are investigated and the reduction in the lift force in close proximity to the ground is discussed.展开更多
文摘Facial sagging is a major aging change that affects the overall shape of the face. Sagging can negatively impact self-perception and consequently quality of life. In order to fight against this aging sign, we developed a combination of three active ingredients: Tetrahydroxypropyl Ethylenediamine (THPE), Ononis Spinosa extract and Glycerin. In a clinical study, we assessed the efficacy of this association on facial sagging and wrinkles, with a special focus on immediate and lasting effects. Thirty-nine women applied the tested product daily during an eight-week treatment period. Clinical grading by experts and a new, easy to operate, 2-D imaging method were performed at different time points. The 2-D imaging method measured the upper eyelid lifting effect. The results showed an immediate and significant improvement in sagging and wrinkle parameters;these benefits were still observed seven hours after the first application. Results also showed a significant long-term improvement. The lifting effect calculated from the 2-D pictures was 1.08 mm immediately after application;the same method showed a 1.80 mm lifting effect following the eight-week treatment period. These results suggest that a skin care product combining THPE, Ononis Spinosa and Glycerin properties may be used to reduce sagging as well as wrinkles with both immediate and long term benefits.
文摘目的比较改良LIFT术与切开挂线引流术治疗复杂性肛瘘的临床疗效。方法选取本院收治的复杂性肛瘘患者108例,其中观察组54例采用改良LIFT术,对照组54例采用传统切开挂线引流术,比较两组疗效、疾病恢复、并发症和复发率等指标。结果观察组治疗总有效率(98.15%)与对照组治疗总有效率(92.59%)比较差异不显著(P>0.05);观察组住院时间、切口愈合时间、切口愈合面积、愈后Wexner评分、术后7 d VAS评分均优于对照组(P<0.05);两组并发症发生率和复发率比较差异不显著(P>0.05)。结论相对于切开挂线引流术,改良LIFT术治疗复杂性肛瘘可有效缩短患者住院和切口愈合时间,减轻术后疼痛,并较好保留肛门功能。
基金financially supported by the National Natural Science Foundation of China(Grant Nos.51490672 and 51761135011)the financial supports by the National Natural Science Foundation of China(Grant No.51490673)the Petro China Innovation Foundation(Grant No.2016D-5007-0601)
文摘Numerical simulations are carried out for wave action on a submerged horizontal circular cylinder by means of a viscous fluid model, and it is focused on the examination of the discrepancies between the viscous fluid results and the potential flow solutions. It is found that the lift force resulted from rotational flow on the circular cylinder is always in anti-phase with the inertia force and induces the discrepancies between the results. The influence factors on the magnitude of the lift force, especially the correlation between the stagnation-point position and the wave amplitude, and the effect of the vortex shedding are investigated by further examination on the flow fields around the cylinder. The viscous numerical calculations at different wave frequencies showed that the wave frequency has also significant influence on the wave forces. Under higher frequency and larger amplitude wave action, vortex shedding from the circular cylinder will appear and influence the wave forces on the cylinder substantially.
文摘Computational simulations of aerodynamic characteristics of the Common Research Model (CRM), representing a typical transport airliner are conducted using CFD methods in close proximity to the ground. The obtained dependencies on bank angle for aerodynamic forces and moments are further used in stability and controllability analysis of the lateral-directional aircraft motion. Essential changes in the lateral-directional modes in close proximity to the ground have been identified. For example, with approach to the ground, the roll subsidence and spiral eigenvalues are merging creating the oscillatory Roll-Spiral mode with quite significant frequency. This transformation of the lateral-directional dynamics in piloted simulation may affect the aircraft responses to external crosswind, modify handling quality characteristics and improve realism of crosswind landing. The material of this paper was presented at the Seventh European Conference for Aeronautics and Space Sciences EUCASS-2017. Further work is carried out for evaluation of the ground effect aerodynamics for a high-lift configuration based on a hybrid geometry of DLR F11 and NASA GTM models with fully deployed flaps and slats. Some aspects of grid generation for a high lift configuration using structured blocking approach are discussed.
文摘Computational prediction of stall aerodynamics in free air and in close proximity to the ground considering the 30P30N three-element high-lift configuration is carried out based on CFD simulations using the OpenFOAM code and Fluent software. Both the attached and separated flow regimes are simulated using the Reynolds Averaged Navier-Stokes (RANS) equations closed with the Spalart-Allamaras (SA) turbulence model for static conditions and pitch oscillations at Reynolds number, <em>Re</em> = 5 x 10<sup>6</sup> and Mach number, <em>M</em> = 0.2. The effects of closeness to the ground and dynamic stall are investigated and the reduction in the lift force in close proximity to the ground is discussed.
