In this pape,we give four methods of discriminations its nonsingularity by utilizing only parametr r1,r2 and elements of the first row of level-2 (r1, r2)-circulant matrices of type (m,n).
The Level-2 probabilistic safety assessment(PSA) of pressurized water reactors studies the possibility of creep rupture for major reactor coolant system components during the course of high pressure severe accident se...The Level-2 probabilistic safety assessment(PSA) of pressurized water reactors studies the possibility of creep rupture for major reactor coolant system components during the course of high pressure severe accident sequences. The present paper covers this technical issue and tries to quantify its associated phenomenological uncertainties for the development of Level-2 PSA. A framework is proposed for the formal quantification of uncertainties in the Level-2 PSA model of a PWR type nuclear power plant using an integrated deterministic and PSA approach. This is demonstrated for estimation of creep rupture failure probability in station blackout severe accident of a 2-loop PWR, which is the representative case for high pressure sequences. MELCOR 1.8.6 code is employed here as the deterministic tool for the assessment of physical phenomena in the course of accident. In addition, a MATLAB code is developed for quantification of the probabilistic part by treating the uncertainties through separation of aleatory and epistemic sources of uncertainty.The probability for steam generator tube creep rupture is estimated at 0.17.展开更多
目的:分析格列吡嗪与二甲双胍联用治疗新发初诊2型糖尿病患者的应用价值。方法:研究对象选取2024年4月至2025年4月在本院收治的102例初诊2型糖尿病患者,以信封法随机分为联合组和二甲双胍组,两组均51例,二甲双胍组予以二甲双胍治疗,联...目的:分析格列吡嗪与二甲双胍联用治疗新发初诊2型糖尿病患者的应用价值。方法:研究对象选取2024年4月至2025年4月在本院收治的102例初诊2型糖尿病患者,以信封法随机分为联合组和二甲双胍组,两组均51例,二甲双胍组予以二甲双胍治疗,联合组予以格列吡嗪联合二甲双胍治疗,两组患者均干预3 m。比较两组血糖水平、空腹C肽、餐后2 h C肽、胰岛β细胞功能指数(Homeostasis model assessment-β,HOMA-β)、胰岛抵抗指数(Homeostasis model assessment-IR,HOMA-IR),统计不良反应。结果:治疗后,联合组在降低糖化血红蛋白、空腹血糖、餐后2 h血糖方面均优于二甲双胍组(P<0.05),两组空腹及餐后2 h C肽均较治疗前有显著升高(P<0.05),且联合组空腹及餐后2 h C肽均高于二甲双胍组(P<0.05),联合组HOMA-β高于二甲双胍组(P<0.05),HOMA-IR低于二甲双胍组(P<0.05),两组不良反应比较无明显差异(P>0.05)。结论:格列吡嗪与二甲双胍联合治疗新发2型糖尿病具有协同降糖效果,能有效改善胰岛β细胞功能,安全性良好。展开更多
文摘In this pape,we give four methods of discriminations its nonsingularity by utilizing only parametr r1,r2 and elements of the first row of level-2 (r1, r2)-circulant matrices of type (m,n).
文摘The Level-2 probabilistic safety assessment(PSA) of pressurized water reactors studies the possibility of creep rupture for major reactor coolant system components during the course of high pressure severe accident sequences. The present paper covers this technical issue and tries to quantify its associated phenomenological uncertainties for the development of Level-2 PSA. A framework is proposed for the formal quantification of uncertainties in the Level-2 PSA model of a PWR type nuclear power plant using an integrated deterministic and PSA approach. This is demonstrated for estimation of creep rupture failure probability in station blackout severe accident of a 2-loop PWR, which is the representative case for high pressure sequences. MELCOR 1.8.6 code is employed here as the deterministic tool for the assessment of physical phenomena in the course of accident. In addition, a MATLAB code is developed for quantification of the probabilistic part by treating the uncertainties through separation of aleatory and epistemic sources of uncertainty.The probability for steam generator tube creep rupture is estimated at 0.17.
文摘目的:分析格列吡嗪与二甲双胍联用治疗新发初诊2型糖尿病患者的应用价值。方法:研究对象选取2024年4月至2025年4月在本院收治的102例初诊2型糖尿病患者,以信封法随机分为联合组和二甲双胍组,两组均51例,二甲双胍组予以二甲双胍治疗,联合组予以格列吡嗪联合二甲双胍治疗,两组患者均干预3 m。比较两组血糖水平、空腹C肽、餐后2 h C肽、胰岛β细胞功能指数(Homeostasis model assessment-β,HOMA-β)、胰岛抵抗指数(Homeostasis model assessment-IR,HOMA-IR),统计不良反应。结果:治疗后,联合组在降低糖化血红蛋白、空腹血糖、餐后2 h血糖方面均优于二甲双胍组(P<0.05),两组空腹及餐后2 h C肽均较治疗前有显著升高(P<0.05),且联合组空腹及餐后2 h C肽均高于二甲双胍组(P<0.05),联合组HOMA-β高于二甲双胍组(P<0.05),HOMA-IR低于二甲双胍组(P<0.05),两组不良反应比较无明显差异(P>0.05)。结论:格列吡嗪与二甲双胍联合治疗新发2型糖尿病具有协同降糖效果,能有效改善胰岛β细胞功能,安全性良好。
