Purpose:To elucidate the impact of mild posterior capsule opacification(PCO)on the visual outcomes in patients with hydrophilic trifocal intraocular lens(IOLs),and to identify objective indicators that can assist in d...Purpose:To elucidate the impact of mild posterior capsule opacification(PCO)on the visual outcomes in patients with hydrophilic trifocal intraocular lens(IOLs),and to identify objective indicators that can assist in determining the need for neodymium:yttrium-aluminum-garnet(Nd:YAG)laser capsulotomy.Methods:This is a prospective observational study.189 patients implanted trifocal IOLs who underwent Nd:YAG laser posterior capsulotomy were recruited.Patients were classified into four grades according to PCO morphology.The distance,intermediate,and near visual acuity(VA),dysfunction lens index(DLI),contrast sensitivity(CS)and visual function(VF-14)scores were measured before and 1 month after Nd:YAG laser capsulotomy.Results:Before Nd:YAG laser capsulotomy,a significant correlation was observed between PCO grading and uncorrected distance VA(UDVA),uncorrected intermediate VA(UIVA),uncorrected near VA(UNVA)visual acuity,corrected distance VA(CDVA),DLI,and VF-14 scores(All P<0.001).However,in patients with PCO grade 1(mild),post-capsulotomy UNVA,DLI,medium and high spatial frequency CS under photopic condition and VF-14 scores were significantly improved compared with pre-capsulotomy values(all P<0.05).The area under the receiver operating characteristic curve for DLI was 0.830(P<0.001),with a corresponding cut-off value of 7.225,indicating its usefulness in assessing the need for Nd:YAG laser capsulotomy in cases of mild PCO.Conclusions:Mild PCO initially impairs near visual acuity in patients with trifocal IOLs and concurrently diminishes both subjective and objective of visual quality.The DLI can serve as an auxiliary diagnostic indicator to assess whether patients with mild PCO may benefit from Nd:YAG laser capsulotomy.展开更多
基金funded by the Chinese National Nature Science Foundation,grant number 82171039.
文摘Purpose:To elucidate the impact of mild posterior capsule opacification(PCO)on the visual outcomes in patients with hydrophilic trifocal intraocular lens(IOLs),and to identify objective indicators that can assist in determining the need for neodymium:yttrium-aluminum-garnet(Nd:YAG)laser capsulotomy.Methods:This is a prospective observational study.189 patients implanted trifocal IOLs who underwent Nd:YAG laser posterior capsulotomy were recruited.Patients were classified into four grades according to PCO morphology.The distance,intermediate,and near visual acuity(VA),dysfunction lens index(DLI),contrast sensitivity(CS)and visual function(VF-14)scores were measured before and 1 month after Nd:YAG laser capsulotomy.Results:Before Nd:YAG laser capsulotomy,a significant correlation was observed between PCO grading and uncorrected distance VA(UDVA),uncorrected intermediate VA(UIVA),uncorrected near VA(UNVA)visual acuity,corrected distance VA(CDVA),DLI,and VF-14 scores(All P<0.001).However,in patients with PCO grade 1(mild),post-capsulotomy UNVA,DLI,medium and high spatial frequency CS under photopic condition and VF-14 scores were significantly improved compared with pre-capsulotomy values(all P<0.05).The area under the receiver operating characteristic curve for DLI was 0.830(P<0.001),with a corresponding cut-off value of 7.225,indicating its usefulness in assessing the need for Nd:YAG laser capsulotomy in cases of mild PCO.Conclusions:Mild PCO initially impairs near visual acuity in patients with trifocal IOLs and concurrently diminishes both subjective and objective of visual quality.The DLI can serve as an auxiliary diagnostic indicator to assess whether patients with mild PCO may benefit from Nd:YAG laser capsulotomy.
