Metabolic control is a major concern for the prevention of met-abolic disorders.Saffron andMelissaofficinalisare natural sources of antiox-idants that can reduce the risk of metabolic diseases.This study aimed to iden...Metabolic control is a major concern for the prevention of met-abolic disorders.Saffron andMelissaofficinalisare natural sources of antiox-idants that can reduce the risk of metabolic diseases.This study aimed to iden-tify and highlight the effects of saffron and Melissaofficinalison glycemic markers.Methods:Four research sources were examined in randomized con-trolled trials on the effects of saffron andMelissaofficinalison glycemic mark-ers.Several studies have explored the effects of saffron andMelissaofficinalis(lemon balm)on glycemic markers and their antidiabetic properties.Some studies have shown positive effects,such as decreased serum levels of FPG in patients with type 2 diabetes.Other studies have shown significant reductions in triglyceride and glycated hemoglobin levels,but no significant difference in glycemic control.Studies have also investigated the effects of saffron with con-current training,resistance training,aerobic training,or both.Conclusion:Research shows that saffron and MelissaofficinalisL significantly affect gly-cemic markers,including FPG,HbA1c,HOMA-IR,and insulin resistance,providing valuable insights for patients with diabetes.Future research should explore the effects of saffron and MelissaofficinalisL on glycemic markers,involvinginvitroandinvivostudies and larger randomized controlled trials.展开更多
The possibility for perspective growing of medicinal, aromatic and spice plants, can be expected only if their cultivation is based on the principles of organic farming. The cultivation of this group of plants is usua...The possibility for perspective growing of medicinal, aromatic and spice plants, can be expected only if their cultivation is based on the principles of organic farming. The cultivation of this group of plants is usually associated with satisfactory yield level and raw materials with uniform quality. This paper contains the most important features of lemon balm （Melissa officinalis）, and methods of cultivation. Data of two annual activities are presented and they are related with organic system of cultivation in the central part of Macedonia. The objective of this study is to analyze, determine and demonstrate the economic viability of lemon balm organic production with irrigation. In the first year, there were only two moving, yielding 500 kg/ha of above-ground plant dry mass. In the second year, there were three moving, yielding 6,775 kg/ha of above-ground plant dry mass. Economic analysis is proved that profitability in organically produced lemon balm is obtained in the second year of growing when the profit reached $6,150/ha.展开更多
The effect of different constant air temperatures (18°C, 21°C, 24°C and 27°C) and variable temperatures (24°C/18°C and 27°C/15°C in 12 h/12 h periods) on basil, sage, thyme, lem...The effect of different constant air temperatures (18°C, 21°C, 24°C and 27°C) and variable temperatures (24°C/18°C and 27°C/15°C in 12 h/12 h periods) on basil, sage, thyme, lemon balm, cilantro, rosemary, oregano and rocket was studied. Supplementary lighting was given 16 h·day-1 at a photon flux density (PFD) of 150 μmol·m-2·s-1 (corresponding to 8.6 mol·m-2·day-1 photosynthetic active radiation [PAR]). Including daylight the PAR was 29.6 ± 6.9 mol·m-2·day-1 as a mean during the experimental period. Increasing the temperature from 18°C to 27°C increased the fresh weight in basil (106%), sage (95%), rosemary (126%) and rocket (62%), while an increase from 18°C to 24°C increased the weight in lemon balm (78%), cilantro (41%), oregano (40%) and thyme (58%). For the last four species the fresh weight was unaffected by a further increase to 27°C. No significant difference was found between the 24°C/18°C and 27°C/15°C treatments. These treatments gave a mean temperature of about 21°C, and no significant differences were found between these treatments and the constant 21°C treatment. The plant height generally increased in the same proportion as the fresh weight increased in the different species. No differences were visually observed between the treatments after two weeks under indoor conditions. All species remained green except cilantro and rocket, for which some leaf yellowing took place. A simple test indicated that the flavour increased with increasing temperature (from 18°C to 27°C) in all species except cilantro.展开更多
Alzheimer disease(AD) as worldwide progressive neurodegenerative disease is prevalent disease among elderly population. Due to limitation in chemical drugs along with their adverse effects of these treatments, researc...Alzheimer disease(AD) as worldwide progressive neurodegenerative disease is prevalent disease among elderly population. Due to limitation in chemical drugs along with their adverse effects of these treatments, research for finding more effective natural drugs, is one of interesting subjects among the scientists. Melissa officinalis(M. officinalis) has a long history of use in treatment of nervous system diseases. This review article evaluates the potency of M. officinalis in treatment of AD by review of experimental and clinical documents on the efficacy, safety and its mechanisms of action in management of AD. The information is extracted from electronic resources(PubMed, Wiley, Springer and Science Direct), English and Persian scientific books. In spite of different scientific and non-scientific reports on the use of M. officinalis and its main component of rosmarinic acid in neurodegenerative diseases, there is only one clinical trial on the efficacy of M. officinalis ethanol extract in management of AD. Different mechanisms of action for M. officinalis, including inhibitory effects against amyloid beta, reactive oxygen species, and acetylcholine esterase, are involved. Larger clinical trials are recommended to confirm the efficacy and safety of M. officinalis extracts in treatment of AD patients.展开更多
For this aim, this study conducted in order to assess the effect of lemon balm as an antioxidant on second degree wound healing and oxidative stress serum of burning patients. To meet the aim, 60 patients with 15 to 5...For this aim, this study conducted in order to assess the effect of lemon balm as an antioxidant on second degree wound healing and oxidative stress serum of burning patients. To meet the aim, 60 patients with 15 to 50 burn percent with the age range of 18 to 50 were invited after considering to inclusion criteria by the researchers. First they have been put by non-probable method and then random method in two groups of experiment (30 people) and control (30 people). After that, experiment group in addition to ordinary treatment has been used Melissa officinalis (lemon balm) plant two times a day for two weeks (1.5 g in 100 cc). Oxidative stress parameters included serum total antioxidant and the rate of malondialdehyde (MDA) that is one of total production of lipid peroxidation have been measured in patients’ blood sample in first and last parts of the study. The wound position has been studied by using standard wound BATES-JENSEN assessment tool in first, seventh and fifteenth days of study. In order to analyze data, independent sample t-test, paired sample t-test and repeated measurement variance have been used. These results indicated that the state of wound healing in experimental group was better than that in control group. Results indicated that mean of serum total antioxidant had been increased in both groups. The index of lipid peroxidation at the end of period has been increased in experiment group than control group, whether this index is significantly decreased at the end of 15 days in experimental group. According to the results of this study, the effect of Melissa officinalis (lemon balm) plant was effective in increasing lipid peroxideative in better states of second degree burn wound healing.展开更多
Medicinal plants are considered as natural sources of antioxidant compounds which may protect organisms against oxidative stresses. The aim of this study was to evaluate the potential of Cinnamon and Melissa officinal...Medicinal plants are considered as natural sources of antioxidant compounds which may protect organisms against oxidative stresses. The aim of this study was to evaluate the potential of Cinnamon and Melissa officinalis L. (Lemon balm) on the improvement of oxidative stress in glass production workers. This clinical study was conducted on 32 glass production workers. They were asked to use 0.5 g of tea-Cinnamon and 3 g of Lemon balm as infusion for 30 days in the morning and evening each day. At the beginning and the end of the study, blood samples were taken from individuals to determine the level of fasting blood suger (FBS), aspartate transaminase (AST), alanintransferase (ALT), triglyceride (TG), cholesterol (CL), low-density lipoprotein (LDL), high-density lipoprotein(HDL) levels, lipid peroxidation (LPO), total antioxidant capacity (TAC) and sillies were measured in workers’ blood. At the end of experiment, data were subjected to the paired t-test analysis. Clinical examination was accomplished to record any abnormal signs or symptoms. After treatment, the high-density lipoprotein and TAC of serum significantly increased while the AST and LPO decreased. There were positive correlations between work history and initiative energy disorder of cognitive test. Probably tea-Cinnamon and Lemon balm possesses marked antioxidant activity and, therefore, it can be used to protect individuals from the oxidative stresses. Using supplementary antioxidants may be helpful in the treatment of workers.展开更多
文摘Metabolic control is a major concern for the prevention of met-abolic disorders.Saffron andMelissaofficinalisare natural sources of antiox-idants that can reduce the risk of metabolic diseases.This study aimed to iden-tify and highlight the effects of saffron and Melissaofficinalison glycemic markers.Methods:Four research sources were examined in randomized con-trolled trials on the effects of saffron andMelissaofficinalison glycemic mark-ers.Several studies have explored the effects of saffron andMelissaofficinalis(lemon balm)on glycemic markers and their antidiabetic properties.Some studies have shown positive effects,such as decreased serum levels of FPG in patients with type 2 diabetes.Other studies have shown significant reductions in triglyceride and glycated hemoglobin levels,but no significant difference in glycemic control.Studies have also investigated the effects of saffron with con-current training,resistance training,aerobic training,or both.Conclusion:Research shows that saffron and MelissaofficinalisL significantly affect gly-cemic markers,including FPG,HbA1c,HOMA-IR,and insulin resistance,providing valuable insights for patients with diabetes.Future research should explore the effects of saffron and MelissaofficinalisL on glycemic markers,involvinginvitroandinvivostudies and larger randomized controlled trials.
文摘The possibility for perspective growing of medicinal, aromatic and spice plants, can be expected only if their cultivation is based on the principles of organic farming. The cultivation of this group of plants is usually associated with satisfactory yield level and raw materials with uniform quality. This paper contains the most important features of lemon balm （Melissa officinalis）, and methods of cultivation. Data of two annual activities are presented and they are related with organic system of cultivation in the central part of Macedonia. The objective of this study is to analyze, determine and demonstrate the economic viability of lemon balm organic production with irrigation. In the first year, there were only two moving, yielding 500 kg/ha of above-ground plant dry mass. In the second year, there were three moving, yielding 6,775 kg/ha of above-ground plant dry mass. Economic analysis is proved that profitability in organically produced lemon balm is obtained in the second year of growing when the profit reached $6,150/ha.
基金This study was supported by Gjennestad Gardener School and the Norwegian Research Council.
文摘The effect of different constant air temperatures (18°C, 21°C, 24°C and 27°C) and variable temperatures (24°C/18°C and 27°C/15°C in 12 h/12 h periods) on basil, sage, thyme, lemon balm, cilantro, rosemary, oregano and rocket was studied. Supplementary lighting was given 16 h·day-1 at a photon flux density (PFD) of 150 μmol·m-2·s-1 (corresponding to 8.6 mol·m-2·day-1 photosynthetic active radiation [PAR]). Including daylight the PAR was 29.6 ± 6.9 mol·m-2·day-1 as a mean during the experimental period. Increasing the temperature from 18°C to 27°C increased the fresh weight in basil (106%), sage (95%), rosemary (126%) and rocket (62%), while an increase from 18°C to 24°C increased the weight in lemon balm (78%), cilantro (41%), oregano (40%) and thyme (58%). For the last four species the fresh weight was unaffected by a further increase to 27°C. No significant difference was found between the 24°C/18°C and 27°C/15°C treatments. These treatments gave a mean temperature of about 21°C, and no significant differences were found between these treatments and the constant 21°C treatment. The plant height generally increased in the same proportion as the fresh weight increased in the different species. No differences were visually observed between the treatments after two weeks under indoor conditions. All species remained green except cilantro and rocket, for which some leaf yellowing took place. A simple test indicated that the flavour increased with increasing temperature (from 18°C to 27°C) in all species except cilantro.
文摘Alzheimer disease(AD) as worldwide progressive neurodegenerative disease is prevalent disease among elderly population. Due to limitation in chemical drugs along with their adverse effects of these treatments, research for finding more effective natural drugs, is one of interesting subjects among the scientists. Melissa officinalis(M. officinalis) has a long history of use in treatment of nervous system diseases. This review article evaluates the potency of M. officinalis in treatment of AD by review of experimental and clinical documents on the efficacy, safety and its mechanisms of action in management of AD. The information is extracted from electronic resources(PubMed, Wiley, Springer and Science Direct), English and Persian scientific books. In spite of different scientific and non-scientific reports on the use of M. officinalis and its main component of rosmarinic acid in neurodegenerative diseases, there is only one clinical trial on the efficacy of M. officinalis ethanol extract in management of AD. Different mechanisms of action for M. officinalis, including inhibitory effects against amyloid beta, reactive oxygen species, and acetylcholine esterase, are involved. Larger clinical trials are recommended to confirm the efficacy and safety of M. officinalis extracts in treatment of AD patients.
文摘For this aim, this study conducted in order to assess the effect of lemon balm as an antioxidant on second degree wound healing and oxidative stress serum of burning patients. To meet the aim, 60 patients with 15 to 50 burn percent with the age range of 18 to 50 were invited after considering to inclusion criteria by the researchers. First they have been put by non-probable method and then random method in two groups of experiment (30 people) and control (30 people). After that, experiment group in addition to ordinary treatment has been used Melissa officinalis (lemon balm) plant two times a day for two weeks (1.5 g in 100 cc). Oxidative stress parameters included serum total antioxidant and the rate of malondialdehyde (MDA) that is one of total production of lipid peroxidation have been measured in patients’ blood sample in first and last parts of the study. The wound position has been studied by using standard wound BATES-JENSEN assessment tool in first, seventh and fifteenth days of study. In order to analyze data, independent sample t-test, paired sample t-test and repeated measurement variance have been used. These results indicated that the state of wound healing in experimental group was better than that in control group. Results indicated that mean of serum total antioxidant had been increased in both groups. The index of lipid peroxidation at the end of period has been increased in experiment group than control group, whether this index is significantly decreased at the end of 15 days in experimental group. According to the results of this study, the effect of Melissa officinalis (lemon balm) plant was effective in increasing lipid peroxideative in better states of second degree burn wound healing.
文摘Medicinal plants are considered as natural sources of antioxidant compounds which may protect organisms against oxidative stresses. The aim of this study was to evaluate the potential of Cinnamon and Melissa officinalis L. (Lemon balm) on the improvement of oxidative stress in glass production workers. This clinical study was conducted on 32 glass production workers. They were asked to use 0.5 g of tea-Cinnamon and 3 g of Lemon balm as infusion for 30 days in the morning and evening each day. At the beginning and the end of the study, blood samples were taken from individuals to determine the level of fasting blood suger (FBS), aspartate transaminase (AST), alanintransferase (ALT), triglyceride (TG), cholesterol (CL), low-density lipoprotein (LDL), high-density lipoprotein(HDL) levels, lipid peroxidation (LPO), total antioxidant capacity (TAC) and sillies were measured in workers’ blood. At the end of experiment, data were subjected to the paired t-test analysis. Clinical examination was accomplished to record any abnormal signs or symptoms. After treatment, the high-density lipoprotein and TAC of serum significantly increased while the AST and LPO decreased. There were positive correlations between work history and initiative energy disorder of cognitive test. Probably tea-Cinnamon and Lemon balm possesses marked antioxidant activity and, therefore, it can be used to protect individuals from the oxidative stresses. Using supplementary antioxidants may be helpful in the treatment of workers.
