BACKGROUND Suicide is a leading cause of preventable death worldwide,with its peak of maximum incidence in later life.Depression often puts an individual at higher risk for suicidal behaviour.In turn,depression deserv...BACKGROUND Suicide is a leading cause of preventable death worldwide,with its peak of maximum incidence in later life.Depression often puts an individual at higher risk for suicidal behaviour.In turn,depression deserves particular interest in old age due to its high prevalence and dramatic impact on health and wellbeing.AIM To gather integrated evidence on the potential risk factors for suicide behaviour development in depressive older adults,and to examine the effects of depression treatment to tackle suicide behaviour in this population.METHODS A systematic review of empirical studies,published from 2000 onwards,was conducted.Suicidal behaviour was addressed considering its varying forms(i.e.,wish to die,ideation,attempt,and completed suicide).RESULTS Thirty-five papers were selected for review,comprising both clinical and epidemiological studies.Most of studies focused on suicidal ideation(60%).The studies consistently pointed out that the risk was related to depressive episode severity,psychiatric comorbidity(anxiety or substance use disorders),poorer health status,and loss of functionality.Reduced social support and loneliness were also associated with suicide behaviour in depressive older adults.Finally,the intervention studies showed that suicidal behaviour was a robust predictor of depression treatment response.Reductions in suicidal ideation were moderated by reductions in risk factors for suicide symptoms.CONCLUSION To sum up,common and age-specific risk factors seem to be involved in suicide development in depressive older adults.A major effort should be made to tackle this serious public health concern so as to promote older people to age healthily and well.展开更多
目的分析近十年老年抑郁领域的国内外研究进展,以期为未来老年抑郁研究提供参考。方法分别检索CNKI数据库与Web of Science核心合集2015年1月1日—2024年8月25日发表的老年抑郁相关中英文文献,运用CiteSpace、VOSviewer软件,通过作者与...目的分析近十年老年抑郁领域的国内外研究进展,以期为未来老年抑郁研究提供参考。方法分别检索CNKI数据库与Web of Science核心合集2015年1月1日—2024年8月25日发表的老年抑郁相关中英文文献,运用CiteSpace、VOSviewer软件,通过作者与机构合作网络、关键词共现网络、聚类分析、爆发词分析等方法进行文献计量学分析,并对中英文文献进行对比。结果共纳入495篇中文文献与4446篇英文文献。中文文献发文量波动小、数量少,英文文献年发文量呈缓慢上升趋势。中英文领域均形成核心作者团队与合作网络,且英文文献广度与深度更优。社会支持、药物治疗、焦虑是二者共同的热点话题,中文文献侧重特殊人群与社会因素,英文文献形成了流行病学特征、认知损害关联、危险因素、焦虑共病与干预手段等聚类。高被引文献中文以流行病学研究为主,英文多为综述与指南类。结论近十年老年抑郁领域已形成丰富的研究积累,但老年患者的特殊社会与生理特点以及更合理的治疗手段仍需进一步探讨。中文文献尚处起步阶段,需提升关注程度与体系化水平,丰富新型药物临床证据;英文文献稳步发展,需加强专属老年抑郁人群的研究。展开更多
基金Supported by Instituto de Salud Carlos III-FIS,co-supported by European Regional Development Fund(ERDF)’a way to build Europe’,No.PI20/00229 and No.PI19/01256。
文摘BACKGROUND Suicide is a leading cause of preventable death worldwide,with its peak of maximum incidence in later life.Depression often puts an individual at higher risk for suicidal behaviour.In turn,depression deserves particular interest in old age due to its high prevalence and dramatic impact on health and wellbeing.AIM To gather integrated evidence on the potential risk factors for suicide behaviour development in depressive older adults,and to examine the effects of depression treatment to tackle suicide behaviour in this population.METHODS A systematic review of empirical studies,published from 2000 onwards,was conducted.Suicidal behaviour was addressed considering its varying forms(i.e.,wish to die,ideation,attempt,and completed suicide).RESULTS Thirty-five papers were selected for review,comprising both clinical and epidemiological studies.Most of studies focused on suicidal ideation(60%).The studies consistently pointed out that the risk was related to depressive episode severity,psychiatric comorbidity(anxiety or substance use disorders),poorer health status,and loss of functionality.Reduced social support and loneliness were also associated with suicide behaviour in depressive older adults.Finally,the intervention studies showed that suicidal behaviour was a robust predictor of depression treatment response.Reductions in suicidal ideation were moderated by reductions in risk factors for suicide symptoms.CONCLUSION To sum up,common and age-specific risk factors seem to be involved in suicide development in depressive older adults.A major effort should be made to tackle this serious public health concern so as to promote older people to age healthily and well.
文摘目的分析近十年老年抑郁领域的国内外研究进展,以期为未来老年抑郁研究提供参考。方法分别检索CNKI数据库与Web of Science核心合集2015年1月1日—2024年8月25日发表的老年抑郁相关中英文文献,运用CiteSpace、VOSviewer软件,通过作者与机构合作网络、关键词共现网络、聚类分析、爆发词分析等方法进行文献计量学分析,并对中英文文献进行对比。结果共纳入495篇中文文献与4446篇英文文献。中文文献发文量波动小、数量少,英文文献年发文量呈缓慢上升趋势。中英文领域均形成核心作者团队与合作网络,且英文文献广度与深度更优。社会支持、药物治疗、焦虑是二者共同的热点话题,中文文献侧重特殊人群与社会因素,英文文献形成了流行病学特征、认知损害关联、危险因素、焦虑共病与干预手段等聚类。高被引文献中文以流行病学研究为主,英文多为综述与指南类。结论近十年老年抑郁领域已形成丰富的研究积累,但老年患者的特殊社会与生理特点以及更合理的治疗手段仍需进一步探讨。中文文献尚处起步阶段,需提升关注程度与体系化水平,丰富新型药物临床证据;英文文献稳步发展,需加强专属老年抑郁人群的研究。
