Objective: Superior Capsular Reconstruction (SCR) using a Tensor Fascia Lata (TFL) autograft is an evolving technique for treating irreparable rotator cuff tears. The Mihata technique, initially developed in Japan, ha...Objective: Superior Capsular Reconstruction (SCR) using a Tensor Fascia Lata (TFL) autograft is an evolving technique for treating irreparable rotator cuff tears. The Mihata technique, initially developed in Japan, has shown promising long-term results. However, a standardized post-operative rehabilitation protocol for this procedure in the USA is lacking. Purpose: This study aims to evaluate the outcomes of a comprehensive rehabilitation protocol following SCR with TFL autograft in a cohort of nine patients. Participants and Methods: A prospective observational study was conducted at Concentra Urgent Care, San Francisco. Nine patients, aged 55 - 65 years, underwent SCR with TFL autograft performed by a specialized orthopedic surgeon. Post-operative rehabilitation was managed using a structured protocol, divided into three phases focusing on passive exercises, progressive range of motion, and strengthening. Outcomes were measured using the Visual Analogue Scale (VAS) for pain, forward flexion range of motion (FF-ROM), and Single Assessment Numeric Evaluation (SANE) scores over a six-month period. Results: Significant improvements were observed in pain reduction (mean VAS decrease of −3.67 points, p = 0.01), ROM (mean FF increase of 41.11 degrees, p = 0.014), and SANE scores (mean improvement of 42.11%, p = 0.009), indicating the efficacy of the rehabilitation protocol. Conclusion: The comprehensive rehabilitation protocol following SCR with TFL autograft significantly improved pain, range of motion, and shoulder function in patients, suggesting its potential utility in clinical practice.展开更多
DEAR EDITOR,Using Oxford Nanopore and Hi-C sequencing technology,we successfully assembled a chromosome-level genome of the Tibetan fox(Vulpes ferrilata),with a total size of 2.38 Gb and N50 length of 133960477 bp.The...DEAR EDITOR,Using Oxford Nanopore and Hi-C sequencing technology,we successfully assembled a chromosome-level genome of the Tibetan fox(Vulpes ferrilata),with a total size of 2.38 Gb and N50 length of 133960477 bp.The 157 contigs were further assembled into 18 chromosomes with a sequence length of2378.42 Mb,accounting for 99.95%of the total length.展开更多
Background: Foreign body granuloma is a rare late complication of fascia lata graft donor site with few reported cases in the literature. It can mimic soft tissue sarcoma. Clinical and radiological findings may not be...Background: Foreign body granuloma is a rare late complication of fascia lata graft donor site with few reported cases in the literature. It can mimic soft tissue sarcoma. Clinical and radiological findings may not be enough to solve the puzzle and histology remains the mainstay of diagnosis. Aim: Our aim is to highlight the unusual long interval between initial surgery and presentation of foreign body granuloma. Case Presentation: A 65-year-old man who presented 48 years after initial surgery with progressive painless fascia lata donor site soft tissue swelling. The management and histology findings were highlighted. Conclusion: The occurrence of foreign body granuloma remains an important differential following a history of past surgical procedure regardless of the time interval between the surgical procedure and the clinical presentation.展开更多
Twenty years after the last archaeological researches and surveys, a new investigation has been carried out on the basement in the church of Santa Maria in Via Lata in Rome. The study has employed three-dimensional su...Twenty years after the last archaeological researches and surveys, a new investigation has been carried out on the basement in the church of Santa Maria in Via Lata in Rome. The study has employed three-dimensional surveys with laser scanning methodology and has focused both on archaeological and architectural issues. Indeed, the present layout of the basement derives from a XVII century remodelling of early Christian and medieval spaces planned by Pietro da Cortona. The architect gave a unique setting and composition to the underground spaces, different in shapes and building materials, thanks to the refinement of his baroque language. Though he worked in small spaces with static problems connected to the foundations and to the loads of the church rising above, and with poor lighting and extreme dampness, Pietro da Cortona put skilfully together “modern” elements with ancient or historical pre-existences. The study focuses on Berrettini’s design process through a three-dimensional analysis with CAD systems, starting from the new XVII century fa?ade and from the articulated distribution of routes that led to the intimate underground interiors. Metrical processing gave the possibility to improve the knowledge about room geometry and to confirm the interpretations put forward by major scholars such as Krautheimer and Cavazzi.展开更多
为预测及综合防治豆科植物的害虫长额负蝗(Atractomorpha lata Motschoulsky),研究温度对长额负蝗生长发育、存活和繁殖的影响,在室内人工气候箱16、20、24、28和32℃共5个恒温条件下,以大豆豆叶为寄主进行饲养,研究温度对长额负蝗的各...为预测及综合防治豆科植物的害虫长额负蝗(Atractomorpha lata Motschoulsky),研究温度对长额负蝗生长发育、存活和繁殖的影响,在室内人工气候箱16、20、24、28和32℃共5个恒温条件下,以大豆豆叶为寄主进行饲养,研究温度对长额负蝗的各虫态发育历期、发育速率及存活率的影响。结果表明:在16℃条件下长额负蝗无法完成世代发育。在试验温度范围内,卵、若虫和全世代平均发育历期随温度升高而缩短,成虫寿命为先升高再降低,通过拟合方程得出发育速率与温度呈正相关。采用直线回归法计算出长额负蝗卵期、若虫期、成虫期和全世代发育起点温度分别为10.81、14.50、18.98、15.17℃,有效积温分别为464.91、453.43、148.41和1078.41 d·℃。长额负蝗成虫产卵量在24℃时最高,为80.37粒/雌,20℃最低,为26.47粒/雌,在20~32℃条件下,种群趋势指数I均大于1,24℃时I值最大,为11.31。温度对长额负蝗存活率影响显著。研究结果可为长额负蝗发生期预测及综合防治提供理论依据。展开更多
目的探讨关节镜下肩峰下自体阔筋膜垫片植入治疗不可修复性巨大肩袖撕裂的临床疗效。方法回顾性分析2019年12月至2023年3月佛山市中医院采用关节镜下肩峰下自体阔筋膜垫片植入治疗的不可修复性巨大肩袖撕裂患者16例,男13例,女3例;年龄58...目的探讨关节镜下肩峰下自体阔筋膜垫片植入治疗不可修复性巨大肩袖撕裂的临床疗效。方法回顾性分析2019年12月至2023年3月佛山市中医院采用关节镜下肩峰下自体阔筋膜垫片植入治疗的不可修复性巨大肩袖撕裂患者16例,男13例,女3例;年龄58~68岁,平均(61.91±3.92)岁;右肩10例,左肩6例;10例患肩为主力侧。术前症状持续时间2~50个月,平均(15.02±12.53)个月,6例有外伤史,所有病例均为初次手术。术后采用肩关节活动度、疼痛视觉模拟评分(visual analogue scale,VAS)、美国肩肘外科协会(American shoulder and elbow surgeons,ASES)评分、美国加利福尼亚大学洛杉矶分校(University of California Los Angeles,UCLA)肩关节评分、Constant-Murley评分评估肩关节功能。结果患者随访时间24~63个月,平均(43.51±19.50)个月。无一例患者出现发热、感染、关节粘连、神经功能障碍等并发症,末次随访时平均肩峰-肱骨头间距(acromiohumeral distance,AHD)由术前的(5.42±1.10)mm提升至(7.03±0.64)mm,前屈、外展、体侧外旋、外展90°位外旋主动活动度分别由术前的(98.21±40.42)°、(70.65±14.42)°、(19.33±11.51)°、(13.57±8.23)°提高至(130.52±23.64)°、(94.62±9.37)°、(42.40±11.76)°、(55.43±15.86)°,差异均有统计学意义(P<0.05)。末次随访VAS为(1.82±0.91)分,较术前的(7.45±2.34)分明显降低,差异有统计学意义(P<0.01)。末次随访ASES评分为(93.64±5.82)分、UCLA评分为(32.83±1.92)分、Constant-Murley评分为(86.72±6.55)分,较术前的(34.31±15.44)分、(10.81±5.23)分、(34.57±14.91)分提高,差异均有统计学意义(P<0.01)。术后2年9例患者非常满意,5例患者满意,2例患者不满意。结论关节镜下肩峰下自体阔筋膜垫片植入治疗不可修复性巨大肩袖撕裂可获得满意的临床疗效,可明显缓解患者疼痛症状,改善关节活动度,恢复关节功能。展开更多
This study created a new type of inflatable metamorphic origami that has the advantage of being a highly simplified deployable system capable of realizing multiple sequential motion patterns with a monolithic actuation.
Tensor fascia lata(TFL)flap is a versatile myofasciocutaneous flap.It has varied usages as both free and pedicled flap.As a pedicled flap,it is a good option for reconstructing soft tissue defects after tumor ablation...Tensor fascia lata(TFL)flap is a versatile myofasciocutaneous flap.It has varied usages as both free and pedicled flap.As a pedicled flap,it is a good option for reconstructing soft tissue defects after tumor ablation.The TFL perforator flap is a good alternative for anterolateral thigh(ALT)flap.The advantages of TFL flap are that dissection can be made through the same incision,without impairment of other donor sites.The reconstructive plan remains same as that of ALT flap.TFL flap offers a good volume of skin and can be made thin removing variable portions of muscle.The present case is a 63-year-old patient with a carcinoma penis who underwent left ilioinguinal block dissection resulting in a defect of 8 cm×8 cm in the left inguinal region.TFL flap was raised with U-shaped incision and used for closure of the defect with good result.展开更多
Screening for maternal syphilis has been an essential component of routine antenatal screening tests in most countries for many years. This is not only because of the virulence of the spirochete which causes the infec...Screening for maternal syphilis has been an essential component of routine antenatal screening tests in most countries for many years. This is not only because of the virulence of the spirochete which causes the infection but also because of its vertical transmission rate and the potential severe adverse complications/morbidity that can result from its transmission to the fetus. Although the incidence of maternal syphilis and its fetal sequalae in low-income countries has been considerable for several years, the disease has been almost non-existent in high income countries with wide antenatal screening coverage and effective treatment programmes for Syphilis. The recent alarming increase in the incidence of maternal syphilis in high income countries has spawned a renewed public health interest in the infection, with several countries updating and strengthening public health guidance in an attempt to stem this dramatic trend. This is a short clinical update for the practising obstetrician on how to manage the antenatal patient with a positive syphilis screening test.展开更多
Background: Peyronie’s disease is characterized by fibrous plaque formation in the tunica albuginea, leading to penile curvature and sexual dysfunction. Surgical correction is often required in cases of severe deform...Background: Peyronie’s disease is characterized by fibrous plaque formation in the tunica albuginea, leading to penile curvature and sexual dysfunction. Surgical correction is often required in cases of severe deformity or significant functional impairment. Aim: To present the case of a patient with severe Peyronie’s disease who underwent surgical correction using an autologous fascia lata graft. Case Presentation: We report the case of a 77-year-old Black-African gentleman with Peyronie’s disease, presenting with a self-reported penile curvature of 70 degrees and significant sexual frustration. He was managed surgically with plaque excision followed by a tunica albuginea patch using a subcutaneously harvested autologous fascia lata graft, all performed in a single surgical session. Conclusion: This case highlights the importance of individualized surgical planning and patient-specific considerations in achieving optimal outcomes in the management of Peyronie’s disease, particularly in cases requiring grafting for severe curvature.展开更多
文摘Objective: Superior Capsular Reconstruction (SCR) using a Tensor Fascia Lata (TFL) autograft is an evolving technique for treating irreparable rotator cuff tears. The Mihata technique, initially developed in Japan, has shown promising long-term results. However, a standardized post-operative rehabilitation protocol for this procedure in the USA is lacking. Purpose: This study aims to evaluate the outcomes of a comprehensive rehabilitation protocol following SCR with TFL autograft in a cohort of nine patients. Participants and Methods: A prospective observational study was conducted at Concentra Urgent Care, San Francisco. Nine patients, aged 55 - 65 years, underwent SCR with TFL autograft performed by a specialized orthopedic surgeon. Post-operative rehabilitation was managed using a structured protocol, divided into three phases focusing on passive exercises, progressive range of motion, and strengthening. Outcomes were measured using the Visual Analogue Scale (VAS) for pain, forward flexion range of motion (FF-ROM), and Single Assessment Numeric Evaluation (SANE) scores over a six-month period. Results: Significant improvements were observed in pain reduction (mean VAS decrease of −3.67 points, p = 0.01), ROM (mean FF increase of 41.11 degrees, p = 0.014), and SANE scores (mean improvement of 42.11%, p = 0.009), indicating the efficacy of the rehabilitation protocol. Conclusion: The comprehensive rehabilitation protocol following SCR with TFL autograft significantly improved pain, range of motion, and shoulder function in patients, suggesting its potential utility in clinical practice.
文摘利用乙酰胆碱 (Ach)、微丝解聚剂 (LatA)和维管束固定剂 (FAA)处理萝卜的韧皮部 ,以叶片中可溶性糖和淀粉含量以及14 C 同化物从叶片中的输出量为指标 ,研究 3种药剂对韧皮部同化物运输的调控作用。结果表明 ,低浓度的Ach可有效地促进14 C 同化物向肉质根的运输 ,而LatA和FAA处理则有效抑制14 C 同化物向肉质根的运输。
基金supported by the National Natural Science Foundation of China(31872242,32070405)。
文摘DEAR EDITOR,Using Oxford Nanopore and Hi-C sequencing technology,we successfully assembled a chromosome-level genome of the Tibetan fox(Vulpes ferrilata),with a total size of 2.38 Gb and N50 length of 133960477 bp.The 157 contigs were further assembled into 18 chromosomes with a sequence length of2378.42 Mb,accounting for 99.95%of the total length.
文摘Background: Foreign body granuloma is a rare late complication of fascia lata graft donor site with few reported cases in the literature. It can mimic soft tissue sarcoma. Clinical and radiological findings may not be enough to solve the puzzle and histology remains the mainstay of diagnosis. Aim: Our aim is to highlight the unusual long interval between initial surgery and presentation of foreign body granuloma. Case Presentation: A 65-year-old man who presented 48 years after initial surgery with progressive painless fascia lata donor site soft tissue swelling. The management and histology findings were highlighted. Conclusion: The occurrence of foreign body granuloma remains an important differential following a history of past surgical procedure regardless of the time interval between the surgical procedure and the clinical presentation.
文摘Twenty years after the last archaeological researches and surveys, a new investigation has been carried out on the basement in the church of Santa Maria in Via Lata in Rome. The study has employed three-dimensional surveys with laser scanning methodology and has focused both on archaeological and architectural issues. Indeed, the present layout of the basement derives from a XVII century remodelling of early Christian and medieval spaces planned by Pietro da Cortona. The architect gave a unique setting and composition to the underground spaces, different in shapes and building materials, thanks to the refinement of his baroque language. Though he worked in small spaces with static problems connected to the foundations and to the loads of the church rising above, and with poor lighting and extreme dampness, Pietro da Cortona put skilfully together “modern” elements with ancient or historical pre-existences. The study focuses on Berrettini’s design process through a three-dimensional analysis with CAD systems, starting from the new XVII century fa?ade and from the articulated distribution of routes that led to the intimate underground interiors. Metrical processing gave the possibility to improve the knowledge about room geometry and to confirm the interpretations put forward by major scholars such as Krautheimer and Cavazzi.
文摘为预测及综合防治豆科植物的害虫长额负蝗(Atractomorpha lata Motschoulsky),研究温度对长额负蝗生长发育、存活和繁殖的影响,在室内人工气候箱16、20、24、28和32℃共5个恒温条件下,以大豆豆叶为寄主进行饲养,研究温度对长额负蝗的各虫态发育历期、发育速率及存活率的影响。结果表明:在16℃条件下长额负蝗无法完成世代发育。在试验温度范围内,卵、若虫和全世代平均发育历期随温度升高而缩短,成虫寿命为先升高再降低,通过拟合方程得出发育速率与温度呈正相关。采用直线回归法计算出长额负蝗卵期、若虫期、成虫期和全世代发育起点温度分别为10.81、14.50、18.98、15.17℃,有效积温分别为464.91、453.43、148.41和1078.41 d·℃。长额负蝗成虫产卵量在24℃时最高,为80.37粒/雌,20℃最低,为26.47粒/雌,在20~32℃条件下,种群趋势指数I均大于1,24℃时I值最大,为11.31。温度对长额负蝗存活率影响显著。研究结果可为长额负蝗发生期预测及综合防治提供理论依据。
文摘目的探讨关节镜下肩峰下自体阔筋膜垫片植入治疗不可修复性巨大肩袖撕裂的临床疗效。方法回顾性分析2019年12月至2023年3月佛山市中医院采用关节镜下肩峰下自体阔筋膜垫片植入治疗的不可修复性巨大肩袖撕裂患者16例,男13例,女3例;年龄58~68岁,平均(61.91±3.92)岁;右肩10例,左肩6例;10例患肩为主力侧。术前症状持续时间2~50个月,平均(15.02±12.53)个月,6例有外伤史,所有病例均为初次手术。术后采用肩关节活动度、疼痛视觉模拟评分(visual analogue scale,VAS)、美国肩肘外科协会(American shoulder and elbow surgeons,ASES)评分、美国加利福尼亚大学洛杉矶分校(University of California Los Angeles,UCLA)肩关节评分、Constant-Murley评分评估肩关节功能。结果患者随访时间24~63个月,平均(43.51±19.50)个月。无一例患者出现发热、感染、关节粘连、神经功能障碍等并发症,末次随访时平均肩峰-肱骨头间距(acromiohumeral distance,AHD)由术前的(5.42±1.10)mm提升至(7.03±0.64)mm,前屈、外展、体侧外旋、外展90°位外旋主动活动度分别由术前的(98.21±40.42)°、(70.65±14.42)°、(19.33±11.51)°、(13.57±8.23)°提高至(130.52±23.64)°、(94.62±9.37)°、(42.40±11.76)°、(55.43±15.86)°,差异均有统计学意义(P<0.05)。末次随访VAS为(1.82±0.91)分,较术前的(7.45±2.34)分明显降低,差异有统计学意义(P<0.01)。末次随访ASES评分为(93.64±5.82)分、UCLA评分为(32.83±1.92)分、Constant-Murley评分为(86.72±6.55)分,较术前的(34.31±15.44)分、(10.81±5.23)分、(34.57±14.91)分提高,差异均有统计学意义(P<0.01)。术后2年9例患者非常满意,5例患者满意,2例患者不满意。结论关节镜下肩峰下自体阔筋膜垫片植入治疗不可修复性巨大肩袖撕裂可获得满意的临床疗效,可明显缓解患者疼痛症状,改善关节活动度,恢复关节功能。
基金This work was supported by the National Key R&D Program of China(Grant No.2022YFB4701200)the National Natural Science Foundation of China(Grant Nos.52075113 and 51835002)+3 种基金the Shenzhen Peacock Innovation Team Project(Grant No.KQTD20210811090146075)the Guangdong Science and Technology Research Council(Grant No.2020B1515120064)the Shenzhen Science and Technology Program(Grant No.JCYJ20210324115811033)the Shenzhen Natural Science Fund(Grant No.GXWD20220811151529003).
文摘This study created a new type of inflatable metamorphic origami that has the advantage of being a highly simplified deployable system capable of realizing multiple sequential motion patterns with a monolithic actuation.
文摘Tensor fascia lata(TFL)flap is a versatile myofasciocutaneous flap.It has varied usages as both free and pedicled flap.As a pedicled flap,it is a good option for reconstructing soft tissue defects after tumor ablation.The TFL perforator flap is a good alternative for anterolateral thigh(ALT)flap.The advantages of TFL flap are that dissection can be made through the same incision,without impairment of other donor sites.The reconstructive plan remains same as that of ALT flap.TFL flap offers a good volume of skin and can be made thin removing variable portions of muscle.The present case is a 63-year-old patient with a carcinoma penis who underwent left ilioinguinal block dissection resulting in a defect of 8 cm×8 cm in the left inguinal region.TFL flap was raised with U-shaped incision and used for closure of the defect with good result.
文摘Screening for maternal syphilis has been an essential component of routine antenatal screening tests in most countries for many years. This is not only because of the virulence of the spirochete which causes the infection but also because of its vertical transmission rate and the potential severe adverse complications/morbidity that can result from its transmission to the fetus. Although the incidence of maternal syphilis and its fetal sequalae in low-income countries has been considerable for several years, the disease has been almost non-existent in high income countries with wide antenatal screening coverage and effective treatment programmes for Syphilis. The recent alarming increase in the incidence of maternal syphilis in high income countries has spawned a renewed public health interest in the infection, with several countries updating and strengthening public health guidance in an attempt to stem this dramatic trend. This is a short clinical update for the practising obstetrician on how to manage the antenatal patient with a positive syphilis screening test.
文摘Background: Peyronie’s disease is characterized by fibrous plaque formation in the tunica albuginea, leading to penile curvature and sexual dysfunction. Surgical correction is often required in cases of severe deformity or significant functional impairment. Aim: To present the case of a patient with severe Peyronie’s disease who underwent surgical correction using an autologous fascia lata graft. Case Presentation: We report the case of a 77-year-old Black-African gentleman with Peyronie’s disease, presenting with a self-reported penile curvature of 70 degrees and significant sexual frustration. He was managed surgically with plaque excision followed by a tunica albuginea patch using a subcutaneously harvested autologous fascia lata graft, all performed in a single surgical session. Conclusion: This case highlights the importance of individualized surgical planning and patient-specific considerations in achieving optimal outcomes in the management of Peyronie’s disease, particularly in cases requiring grafting for severe curvature.
