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The 2016 Albert Lasker Basic Medical Research Award: Oxygen sensing—a mysterious process essential for survival 被引量:1
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作者 Ziru Li Weizhen Zhang 《Science China(Life Sciences)》 SCIE CAS CSCD 2016年第11期1195-1197,共3页
The 2016 Albert Lasker Basic Medical Research Award honors three physician-scientists: William G. Kaelin, Jr. from Harvard Medical School, Peter J. Ratcliffe from Uni- versity of Oxford and Gregg L. Semenza, from Joh... The 2016 Albert Lasker Basic Medical Research Award honors three physician-scientists: William G. Kaelin, Jr. from Harvard Medical School, Peter J. Ratcliffe from Uni- versity of Oxford and Gregg L. Semenza, from Johns Hopkins University School of Medicine, for their discovery of the pathway by which cells from human and most animals sense and adapt to changes in oxygen availability, a process essential for survival. The Lasker Award is widely considered as America's mosLt prestigious honor in the biomedical field. For 71 years, 展开更多
关键词 HIF gene a mysterious process essential for survival Oxygen sensing The 2016 Albert lasker Basic Medical Research Award Basic
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2011 Lasker Clinical Medical Research Award Honors Prof.TU You-you for the Discovery of Artemisinin
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《Chinese Journal of Integrative Medicine》 SCIE CAS 2011年第11期802-802,共1页
The 2011 Lasker Clinical Medical Research Award honors a scientist who discovered artemisinin and its utility for treating malaria. Prof. TU You-you (China Academy of Chinese Medical Sciences, Beijing) transformed a... The 2011 Lasker Clinical Medical Research Award honors a scientist who discovered artemisinin and its utility for treating malaria. Prof. TU You-you (China Academy of Chinese Medical Sciences, Beijing) transformed an ancient Chinese healing method into the most powerful antimalarial medicine currently available that has saved millions of lives across the globe, especially in the developing world. An artemisinin-based drug combination is now the standard regimen for malaria recommended by the World Health Organization (WHO). 展开更多
关键词 lasker Clinical Medical Research Award Honors Prof.TU You-you for the Discovery of Artemisinin
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From NF-kB to cGAS:An interview with Prof.Zhijian James Chen on unraveling innate immunity
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作者 Wenwen Zeng Lai Guan Ng +1 位作者 Zhijian James Chen Qun Yan 《hLife》 2025年第6期253-257,共5页
Prof.Zhijian James Chen,a distinguished scientist in the field of innate immunity,has been honored with the 2025 Paul Ehrlich and Ludwig Darmstaedter Prize and the 2024 Albert Lasker Basic Medical Research Award for h... Prof.Zhijian James Chen,a distinguished scientist in the field of innate immunity,has been honored with the 2025 Paul Ehrlich and Ludwig Darmstaedter Prize and the 2024 Albert Lasker Basic Medical Research Award for his groundbreaking discovery of the enzyme cyclic guanosine monophosphate-adenosine monophosphate synthase(cGAS).His research has transformed the understanding of innate immune responses,particularly the role of cGAS as a cytosolic DNA sensor that triggers an interferon response.In this dialogue,Prof.Chen reflects on his research journey,from his initial exploration of ubiquitin and nuclear factor-kB(NF-kB)signaling to his discoveries of mitochondrial antiviral-signaling protein(MAVS)and cGAS,highlighting his lifelong interest in cell signaling and human diseases.The interview underscores the importance of perseverance and the pursuit of impactful research questions in scientific endeavors.This scholarly exchange offers a mentor-like perspective for aspiring scientists,encapsulating the essence of a successful career in biomedical research. 展开更多
关键词 innate immunity nf kb interferon response cgas innate immune responsesparticularly cytosolic dna sensor albert lasker basic medical research award interferon responsein
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