Objective: Laryngeal cancer is an important oncologic entity, whose prognosis depends on establishing appropriate preventive and diagnostic measures, especially in populations at higher risk.Methods: Epidemiologic inf...Objective: Laryngeal cancer is an important oncologic entity, whose prognosis depends on establishing appropriate preventive and diagnostic measures, especially in populations at higher risk.Methods: Epidemiologic information including worldwide incidence, prevalence, burden of health loss(disability-adjusted life year;DALYs) and mortality of larynx cancer was obtained from the Global Health Data Exchange(GHDx) database.Results: The current incidence, prevalence and mortality of laryngeal cancer are estimated at 2.76 cases/year per 100,000 inhabitants, 14.33 cases/year per 100,000 inhabitants and 1.66 deaths/year per 100,000 inhabitants,respectively, averaging 3.28 million DALYs each year. Incidence and prevalence have increased by 12% and 24%,respectively during the past 3 decades, whilst mortality has declined by around 5%. The epidemiologic burden of this malignancy is approximately 5-fold higher in males and increases in parallel with ageing, peaking after 65 years of age. Both incidence and mortality rates are higher in Europe and lower in Africa, but the ratio between deaths and incidence is the highest in Africa. Incidence has gradually declined in Europe during the past 3 decades, whilst it has increased in South-East Asia and Western Pacific. Cigarette smoking and alcohol abuse contribute for about 90% of overall worldwide mortality for laryngeal cancer.Conclusions: Laryngeal cancer still poses a high clinical and societal burden, with an escalating temporal trend not expected to reverse soon.展开更多
Objective: To investigate the application value of midline catheters in patients with larynx cancer during the postoperative period. Methods: 150 patients with larynx cancer treated in our hospital from May 2019 to Ma...Objective: To investigate the application value of midline catheters in patients with larynx cancer during the postoperative period. Methods: 150 patients with larynx cancer treated in our hospital from May 2019 to May 2022 were selected as the study objects. According to the random number method, 75 cases were divided into a control group and a study group. The study group used a midline catheter during treatment, and the control group used a Peripheral venous indwelling needle during treatment. The indwelling time, puncture times, complication rate, daily catheter maintenance cost and catheterization satisfaction rate of the two groups were compared. Result: The retention time of the study group (11.53 ± 6.91 days) was significantly higher than that of the control group (2.92 ± 1.41 days) (P . The total puncture times were significantly lower than that of the control group (P cidence of complications such as catheter blockage, catheter detachment, drug extravasation and phlebitis were lower than those of the control group. The difference was statistically significant (P < 0.05), the average daily maintenance cost of the two groups was not statistically significant (P > 0.05), and the satisfaction rate of the study group was significantly higher than that of the control group, the difference was statistically significant (P Conclusion: Compared with the Peripheral venous indwelling needle, postoperative application of a midline catheter in patients with larynx cancer can effectively reduce the number of puncture times and the incidence of catheter-related adverse reactions, and has higher economic benefits and satisfaction rate, which is worthy of clinical application.展开更多
Background: The collection of data on cancers is essential to assess their importance in a population and plan control strategies. In Benin as in many sub-Saharan Africa countries, cancer data are often not well infor...Background: The collection of data on cancers is essential to assess their importance in a population and plan control strategies. In Benin as in many sub-Saharan Africa countries, cancer data are often not well informed. Purpose: To study the epidemiological and anatomopathological profiles of head and neck cancers. Methods: This was a descriptive cross-sectional study of head and neck cancers in Benin from January 2009 to 31 December 2014. These tumours were collected in the registers of the 5 anatomy-pathological laboratories in Benin as well as in that of the only hospital in the country that sends its requests for histological examination abroad. Results: During the period, 611 cases of head and neck tumour were reported, including 298 malignant cases, or 48.8%. The average age was 45.3 ± 18.7 years (extremes: 1 year and 91 years) with a maximum of cases between 50 and 60 years (19.1%). The sex ratio was 1.2. The cancers occurred mainly in the pharynx (27.9%), the oral cavity (19.8%), the nose, sinuses and jaws (18.1%), the thyroid (12.8%), the salivary glands (8.7%) and the larynx (8.4%). They were of epithelial origin in 79.5% of cases, mainly squamous cell carcinomas (50.3%) and lymphomas in 12.8% of cases. Conclusion: Head and neck cancer is preventable. A special place should be given to the fight against cancer in Benin. Strategies to prevent and manage these cancers cannot be put in place without accurate data collection.展开更多
目的分析1990—2021年间中国因过量饮酒导致的喉癌疾病负担变化趋势,并预测至2040年的趋势,为疾病防控提供参考。方法基于全球疾病负担2021年数据,提取伤残调整生命年(disability adjusted life years,DALYs)和伤残调整生命年率(disabil...目的分析1990—2021年间中国因过量饮酒导致的喉癌疾病负担变化趋势,并预测至2040年的趋势,为疾病防控提供参考。方法基于全球疾病负担2021年数据,提取伤残调整生命年(disability adjusted life years,DALYs)和伤残调整生命年率(disability adjusted life years rate,DALYs),死亡人数和死亡率作为分析指标评估疾病负担;运用分解分析探讨人口增长、老龄化及流行病学改变对疾病负担变化的贡献;利用年龄-时期-队列模型分析不同年龄组、时期、出生队列疾病负担变化趋势;采用贝叶斯年龄-时期-队列(bayesian age-period-cohort,BAPC)模型预测至2040年趋势变化。结果1990—2021年,中国因过量饮酒导致的喉癌DALYs和死亡人数增加,但年龄标准化DALYs率(age standardized disability adjusted life years rate,ASDR)和年龄标准化死亡率(age standardized mortality rate,ASMR)呈下降趋势,相较于全球水平,中国负担较轻;男性的负担显著高于女性,55~59岁和65~69岁为关键年龄段;人口增长是负担增加的主要因素,流行病学改变因素起保护作用。1992—1996年、65~69岁年龄组因过量饮酒导致喉癌的负担最高,年龄较大的出生队列显示出更高负担。预测至2040年,疾病负担将持续下降。结论1990—2021年,中国因过量饮酒导致喉癌的绝对负担持续增长,但年龄标准化率呈下降趋势,预测至2040年将持续降低。流行病学改变减轻了疾病负担,但人口增长和老龄化使绝对负担上升。55岁以上男性群体是疾病负担的重点人群,仍是中国在应对过量饮酒导致喉癌问题上的关键挑战。展开更多
目的分析1990—2019年中国喉癌疾病负担的变化趋势。方法基于全球疾病负担研究数据库对比分析1990—2019年我国和全球喉癌的发病率、死亡率、伤残调整寿命年(disability adjusted life years,DALYs)、过早死亡损失寿命年、伤残损失寿命...目的分析1990—2019年中国喉癌疾病负担的变化趋势。方法基于全球疾病负担研究数据库对比分析1990—2019年我国和全球喉癌的发病率、死亡率、伤残调整寿命年(disability adjusted life years,DALYs)、过早死亡损失寿命年、伤残损失寿命年及年估计变化百分比(estimated annual percentage change,EAPC),并进一步分析我国不同年龄、性别及喉癌归因危险因素的疾病负担情况。结果2019年中国喉癌发病例数、死亡例数和DALYs分别为4.54万、2.03万和49.79万人年,比1990年分别增加了221.98%、76.20%和56.72%。1990—2019年中国喉癌标化发病率呈上升趋势(EAPC=1.32),而标化死亡率(EAPC=-0.96)和标化DALYs率(EAPC=-1.21)均呈下降趋势。我国喉癌的发病、死亡和疾病负担在50~69岁年龄组开始明显上升,≥70岁达到最高,且男性显著高于女性。与1990年相比,2019年我国可归因于吸烟、饮酒和石棉暴露的喉癌死亡比例和DALYs比例均有所增加;可归因于硫酸暴露的喉癌死亡比例和DALYs比例均有所下降。结论1990—2019年我国喉癌的标化发病率呈上升趋势,而标化死亡率和标化DALYs率均呈下降趋势,疾病负担在男性中明显高于女性,中老年人群的疾病负担仍较为沉重,提示仍需进一步加强喉癌的防治工作。展开更多
文摘Objective: Laryngeal cancer is an important oncologic entity, whose prognosis depends on establishing appropriate preventive and diagnostic measures, especially in populations at higher risk.Methods: Epidemiologic information including worldwide incidence, prevalence, burden of health loss(disability-adjusted life year;DALYs) and mortality of larynx cancer was obtained from the Global Health Data Exchange(GHDx) database.Results: The current incidence, prevalence and mortality of laryngeal cancer are estimated at 2.76 cases/year per 100,000 inhabitants, 14.33 cases/year per 100,000 inhabitants and 1.66 deaths/year per 100,000 inhabitants,respectively, averaging 3.28 million DALYs each year. Incidence and prevalence have increased by 12% and 24%,respectively during the past 3 decades, whilst mortality has declined by around 5%. The epidemiologic burden of this malignancy is approximately 5-fold higher in males and increases in parallel with ageing, peaking after 65 years of age. Both incidence and mortality rates are higher in Europe and lower in Africa, but the ratio between deaths and incidence is the highest in Africa. Incidence has gradually declined in Europe during the past 3 decades, whilst it has increased in South-East Asia and Western Pacific. Cigarette smoking and alcohol abuse contribute for about 90% of overall worldwide mortality for laryngeal cancer.Conclusions: Laryngeal cancer still poses a high clinical and societal burden, with an escalating temporal trend not expected to reverse soon.
文摘Objective: To investigate the application value of midline catheters in patients with larynx cancer during the postoperative period. Methods: 150 patients with larynx cancer treated in our hospital from May 2019 to May 2022 were selected as the study objects. According to the random number method, 75 cases were divided into a control group and a study group. The study group used a midline catheter during treatment, and the control group used a Peripheral venous indwelling needle during treatment. The indwelling time, puncture times, complication rate, daily catheter maintenance cost and catheterization satisfaction rate of the two groups were compared. Result: The retention time of the study group (11.53 ± 6.91 days) was significantly higher than that of the control group (2.92 ± 1.41 days) (P . The total puncture times were significantly lower than that of the control group (P cidence of complications such as catheter blockage, catheter detachment, drug extravasation and phlebitis were lower than those of the control group. The difference was statistically significant (P < 0.05), the average daily maintenance cost of the two groups was not statistically significant (P > 0.05), and the satisfaction rate of the study group was significantly higher than that of the control group, the difference was statistically significant (P Conclusion: Compared with the Peripheral venous indwelling needle, postoperative application of a midline catheter in patients with larynx cancer can effectively reduce the number of puncture times and the incidence of catheter-related adverse reactions, and has higher economic benefits and satisfaction rate, which is worthy of clinical application.
文摘Background: The collection of data on cancers is essential to assess their importance in a population and plan control strategies. In Benin as in many sub-Saharan Africa countries, cancer data are often not well informed. Purpose: To study the epidemiological and anatomopathological profiles of head and neck cancers. Methods: This was a descriptive cross-sectional study of head and neck cancers in Benin from January 2009 to 31 December 2014. These tumours were collected in the registers of the 5 anatomy-pathological laboratories in Benin as well as in that of the only hospital in the country that sends its requests for histological examination abroad. Results: During the period, 611 cases of head and neck tumour were reported, including 298 malignant cases, or 48.8%. The average age was 45.3 ± 18.7 years (extremes: 1 year and 91 years) with a maximum of cases between 50 and 60 years (19.1%). The sex ratio was 1.2. The cancers occurred mainly in the pharynx (27.9%), the oral cavity (19.8%), the nose, sinuses and jaws (18.1%), the thyroid (12.8%), the salivary glands (8.7%) and the larynx (8.4%). They were of epithelial origin in 79.5% of cases, mainly squamous cell carcinomas (50.3%) and lymphomas in 12.8% of cases. Conclusion: Head and neck cancer is preventable. A special place should be given to the fight against cancer in Benin. Strategies to prevent and manage these cancers cannot be put in place without accurate data collection.
文摘目的分析1990—2021年间中国因过量饮酒导致的喉癌疾病负担变化趋势,并预测至2040年的趋势,为疾病防控提供参考。方法基于全球疾病负担2021年数据,提取伤残调整生命年(disability adjusted life years,DALYs)和伤残调整生命年率(disability adjusted life years rate,DALYs),死亡人数和死亡率作为分析指标评估疾病负担;运用分解分析探讨人口增长、老龄化及流行病学改变对疾病负担变化的贡献;利用年龄-时期-队列模型分析不同年龄组、时期、出生队列疾病负担变化趋势;采用贝叶斯年龄-时期-队列(bayesian age-period-cohort,BAPC)模型预测至2040年趋势变化。结果1990—2021年,中国因过量饮酒导致的喉癌DALYs和死亡人数增加,但年龄标准化DALYs率(age standardized disability adjusted life years rate,ASDR)和年龄标准化死亡率(age standardized mortality rate,ASMR)呈下降趋势,相较于全球水平,中国负担较轻;男性的负担显著高于女性,55~59岁和65~69岁为关键年龄段;人口增长是负担增加的主要因素,流行病学改变因素起保护作用。1992—1996年、65~69岁年龄组因过量饮酒导致喉癌的负担最高,年龄较大的出生队列显示出更高负担。预测至2040年,疾病负担将持续下降。结论1990—2021年,中国因过量饮酒导致喉癌的绝对负担持续增长,但年龄标准化率呈下降趋势,预测至2040年将持续降低。流行病学改变减轻了疾病负担,但人口增长和老龄化使绝对负担上升。55岁以上男性群体是疾病负担的重点人群,仍是中国在应对过量饮酒导致喉癌问题上的关键挑战。
