In In the Castle of My Skin （hereafter Castle） （1983）, the littoral as trope provides a means for discovering Lamming＇s authorial license, one that speaks to postcolonial and phenomenological aims. In this semi-a...In In the Castle of My Skin （hereafter Castle） （1983）, the littoral as trope provides a means for discovering Lamming＇s authorial license, one that speaks to postcolonial and phenomenological aims. In this semi-autobiographical novel, Lamming examines self-awareness and the process through which language and self-analysis may take shape on or be inspired by the shore＇s edge. Through the telling of personal stories, discussions of a colonial history, and with allusions to the social privations affecting the immediate community, Lamming represents the changing realities, the main characters （＂G＂ and his friends） experience as they become socially aware; he highlights this transformative rise to consciousness through the use of littoral imagery in Chapters Six, Eleven, and Fourteen. In this essay, the author explores these representations using postcolonial, psychoanalytical, and phenomenological approaches, giving particular attention to Chapter Six, the longer chapter where Lamming creates a blueprint of the issues to which he will return in Chapters Eleven and Fourteen. Castle epitomizes the ways in which the littoral as trope has the potential to symbolically impact an author＇s text, especially a means for crafting an authorial language that demonstrates a young man＇s rise to consciousness and self-actualization on the shorelines of Barbados before he emigrates abroad.展开更多
Moringa oleifera Lam.is a Moringa genus in the Moringaceae family that is high in nutrients and has a wide range of applications.Phenolic compounds are widely found in plants and have various health benefits for the h...Moringa oleifera Lam.is a Moringa genus in the Moringaceae family that is high in nutrients and has a wide range of applications.Phenolic compounds are widely found in plants and have various health benefits for the human body.With its high content and wide variety of phenolic compounds,M.oleifera Lam.has been widely studied for its health benefits.The phenolic compounds in M.oleifera Lam.(MOPCs)can be a potential source of functional food ingredients in pharmaceutical and industrial applications.Numerous studies have shown that MOPCs have antioxidant,anti-obesity,anti-diabetic,and antibacterial effects.Although the research on MOPCs has been gradually increasing,the extraction,isolation,identification,biological activities,and comprehensive application of MOPCs need a more systematic summary and generalization.Therefore,this paper reviews the isolation and extraction methods,structure identification,biological activities,and comprehensive applications to provide a further reference for the research and application of MOPCs.展开更多
Additive manufacturing(AM)has emerged as one of the most utilized processes in manufacturing due to its ability to produce complex geometries with minimal material waste and greater design freedom.Laser-based AM(LAM)t...Additive manufacturing(AM)has emerged as one of the most utilized processes in manufacturing due to its ability to produce complex geometries with minimal material waste and greater design freedom.Laser-based AM(LAM)technologies use high-power lasers to melt metallic materials,which then solidify to form parts.However,it inherently induces self-equilibrating residual stress during fabrication due to thermal loads and plastic deformation.These residual stresses can cause defects such as delamination,cracking,and distortion,as well as premature failure under service conditions,necessitating mitigation.While post-treatment methods can reduce residual stresses,they are often costly and time-consuming.Therefore,tuning the fabrication process parameters presents a more feasible approach.Accordingly,in addition to providing a comprehensive view of residual stress by their classification,formation mechanisms,measurement methods,and common post-treatment,this paper reviews and compares the studies conducted on the effect of key parameters of the LAM process on the resulting residual stresses.This review focuses on proactively adjusting LAM process parameters as a strategic approach to mitigate residual stress formation.It provides a result of the various parameters influencing residual stress outcomes,such as laser power,scanning speed,beam diameter,hatch spacing,and scanning strategies.Finally,the paper identifies existing research gaps and proposes future studies needed to deepen understanding of the relationship between process parameters and residual stress mitigation in LAM.展开更多
People living long-term in areas with UV will cause premature photoaging.An abnormal reduction in autophagy is a key feature of photoaging,and p38 MAPK has been regarded as a key regulator of autophagy.Isothiocyanate ...People living long-term in areas with UV will cause premature photoaging.An abnormal reduction in autophagy is a key feature of photoaging,and p38 MAPK has been regarded as a key regulator of autophagy.Isothiocyanate is one of the main active components of Moringa oleifera Lam.seeds.Studies have reported that M.oleifera Lam.seeds iso thiocyanate(MITC)has anticancer,anti-inflammatory,cardio metabolic repair,nervous system protection,blood lipid regulation and diabetes prevention properties.However,the molecular mechanisms of MITC with protective effects against skin photoaging have not been studied thus far.In this study,we aimed to evaluate the antiphotoaging activity of MITC and to investigate the effect of p38 MAPK-dependent autophagy in vivo and in vitro models of photoaging.In this research we found that MITC can reverse the intracellular reactive oxygen species(ROS)content and inhibit the activation of p38 MAPK to improve the autophagy level,reduce the expression of matrix metalloproteinases(MMPs),and finally protect against photoaging by UV.Our results will uncover the molecular mechanisms of MITC that play a role in the protective effects against skin photoaging,provide helpful information for developing MITC as an anti-photoaging plant material and improve the utilization of M.oleifera Lam.seeds.展开更多
文摘In In the Castle of My Skin （hereafter Castle） （1983）, the littoral as trope provides a means for discovering Lamming＇s authorial license, one that speaks to postcolonial and phenomenological aims. In this semi-autobiographical novel, Lamming examines self-awareness and the process through which language and self-analysis may take shape on or be inspired by the shore＇s edge. Through the telling of personal stories, discussions of a colonial history, and with allusions to the social privations affecting the immediate community, Lamming represents the changing realities, the main characters （＂G＂ and his friends） experience as they become socially aware; he highlights this transformative rise to consciousness through the use of littoral imagery in Chapters Six, Eleven, and Fourteen. In this essay, the author explores these representations using postcolonial, psychoanalytical, and phenomenological approaches, giving particular attention to Chapter Six, the longer chapter where Lamming creates a blueprint of the issues to which he will return in Chapters Eleven and Fourteen. Castle epitomizes the ways in which the littoral as trope has the potential to symbolically impact an author＇s text, especially a means for crafting an authorial language that demonstrates a young man＇s rise to consciousness and self-actualization on the shorelines of Barbados before he emigrates abroad.
基金supported by Major Project of Science and Technology Department of Yunnan Province(202002AA100005,202102AE090027-2)National Natural Science Foundation of China(82260703)+1 种基金Cassava Industrial Technology System of China(CARS11-YNTY)Yunnan Province Ten Thousand Plan Industrial Technology Talents Project(YNWR-CYJS-2020-010)。
文摘Moringa oleifera Lam.is a Moringa genus in the Moringaceae family that is high in nutrients and has a wide range of applications.Phenolic compounds are widely found in plants and have various health benefits for the human body.With its high content and wide variety of phenolic compounds,M.oleifera Lam.has been widely studied for its health benefits.The phenolic compounds in M.oleifera Lam.(MOPCs)can be a potential source of functional food ingredients in pharmaceutical and industrial applications.Numerous studies have shown that MOPCs have antioxidant,anti-obesity,anti-diabetic,and antibacterial effects.Although the research on MOPCs has been gradually increasing,the extraction,isolation,identification,biological activities,and comprehensive application of MOPCs need a more systematic summary and generalization.Therefore,this paper reviews the isolation and extraction methods,structure identification,biological activities,and comprehensive applications to provide a further reference for the research and application of MOPCs.
文摘Additive manufacturing(AM)has emerged as one of the most utilized processes in manufacturing due to its ability to produce complex geometries with minimal material waste and greater design freedom.Laser-based AM(LAM)technologies use high-power lasers to melt metallic materials,which then solidify to form parts.However,it inherently induces self-equilibrating residual stress during fabrication due to thermal loads and plastic deformation.These residual stresses can cause defects such as delamination,cracking,and distortion,as well as premature failure under service conditions,necessitating mitigation.While post-treatment methods can reduce residual stresses,they are often costly and time-consuming.Therefore,tuning the fabrication process parameters presents a more feasible approach.Accordingly,in addition to providing a comprehensive view of residual stress by their classification,formation mechanisms,measurement methods,and common post-treatment,this paper reviews and compares the studies conducted on the effect of key parameters of the LAM process on the resulting residual stresses.This review focuses on proactively adjusting LAM process parameters as a strategic approach to mitigate residual stress formation.It provides a result of the various parameters influencing residual stress outcomes,such as laser power,scanning speed,beam diameter,hatch spacing,and scanning strategies.Finally,the paper identifies existing research gaps and proposes future studies needed to deepen understanding of the relationship between process parameters and residual stress mitigation in LAM.
基金supported by National Natural Science Foundation of China(82260703)。
文摘People living long-term in areas with UV will cause premature photoaging.An abnormal reduction in autophagy is a key feature of photoaging,and p38 MAPK has been regarded as a key regulator of autophagy.Isothiocyanate is one of the main active components of Moringa oleifera Lam.seeds.Studies have reported that M.oleifera Lam.seeds iso thiocyanate(MITC)has anticancer,anti-inflammatory,cardio metabolic repair,nervous system protection,blood lipid regulation and diabetes prevention properties.However,the molecular mechanisms of MITC with protective effects against skin photoaging have not been studied thus far.In this study,we aimed to evaluate the antiphotoaging activity of MITC and to investigate the effect of p38 MAPK-dependent autophagy in vivo and in vitro models of photoaging.In this research we found that MITC can reverse the intracellular reactive oxygen species(ROS)content and inhibit the activation of p38 MAPK to improve the autophagy level,reduce the expression of matrix metalloproteinases(MMPs),and finally protect against photoaging by UV.Our results will uncover the molecular mechanisms of MITC that play a role in the protective effects against skin photoaging,provide helpful information for developing MITC as an anti-photoaging plant material and improve the utilization of M.oleifera Lam.seeds.
