The high incidence of postpartum hypogalactia hinders the healthy development of postpartum women and the next generation.Lacquer seed oil(LSO),extracted from the seeds of the lacquer tree,has been traditionally used ...The high incidence of postpartum hypogalactia hinders the healthy development of postpartum women and the next generation.Lacquer seed oil(LSO),extracted from the seeds of the lacquer tree,has been traditionally used as a dietary supplement for promoting postpartum lactation and recovery in some districts of China.However,its physiological effects have not been verified,and the mechanism and active components of LSO have not been analyzed.Thus,we applied LSO to bromocriptine-induced postpartum hypogalactia rats.The results showed that LSO supplement effectively improves bromocriptine-induced postpartum hypogalactia.LSO also increased prolactin levels reduced by bromocriptine,promoted JAK2/STAT5 and PI3K/AKT pathways and several gene expression levels of milk synthesis in mammary gland.Moreover,metabolomic and network pharmacological analysis further revealed that JAK2/STAT5,PI3K/AKT,and estrogen signaling pathway are the potential main regulatory sites for the beneficial effects of LSO on postpartum hypogalactia,and that quercetin,kaempferol,arachidonic acid,epicatechin,and β-sitosterol are the top 5 main active ingredients of LSO.Our results suggested that LSO has great potential in the application of the improvement of postpartum hypogalactia.展开更多
This study aims to optimize the use of lacquer residue biomass(LBM).We investigated the ability of LBM to remove Pb^(2+)heavy metal ions and the typical cationic dye methylene blue(MB)and anionic dye Congo red(CR)by s...This study aims to optimize the use of lacquer residue biomass(LBM).We investigated the ability of LBM to remove Pb^(2+)heavy metal ions and the typical cationic dye methylene blue(MB)and anionic dye Congo red(CR)by simultaneous adsorption from composite systems,as well as the relevant factors.Scanning electron microscopy(SEM),X-ray diffraction(XRD),and Fourier transform infrared spectroscopy(FTIR)were used to characterize adsorption behavior.The adsorption kinetics of Pb^(2+)-MB/CR composite systems can be effectively characterized by the pseudo-second-order kinetic model(R^(2)>0.97).In the Pb^(2+)-MB composite system,adsorption was antagonistic with similar adsorption sites.However,in the Pb^(2+)-CR composite system,we found that adsorption was synergistic with different adsorption sites,which led to a higher simultaneous adsorption capacity for a higher initial Pb^(2+)-CR concentration,unlike the Pb^(2+)-MB system.In both composite systems,an appropriate increase in LBM dosage and system temperature within a certain range was conducive to simultaneous adsorption and removal of Pb^(2+)-MB/CR composite systems.The optimal solid-liquid ratio and temperature were 1:75 and 30℃,respectively.The adsorption and removal rates of Pb^(2+)and MB were 99.98%and 90.49%,respectively,and those of Pb^(2+)and CR were 93.99%and 77.39%,respectively,in(50,50)mg/L of Pb^(2+)-MB/CR composite systems under these conditions.Adsorption removal of Pb^(2+)and MB improved with higher pH levels,and worsened with the increase of ionic strength in the solution,while the removal rate of CR showed an opposite trend.The coexisting anion and cation types had limited influence on the simultaneous adsorption removal of Pb^(2+),MB,and CR.The results of desorption showed that LBM can be utilized as a disposable material for simultaneously treating Pb^(2+)-MB/CR composite systems.The simultaneous adsorption mechanisms of Pb^(2+)-MB/CR mainly involved hydrogen bonding,π-πbonding interaction,and electrostatic interaction.展开更多
Industrial paints exacerbate air pollution by emitting volatile organic compounds during application and drying processes.This study seeks to enhance the efficiency of Chinese natural paints and increase their accessi...Industrial paints exacerbate air pollution by emitting volatile organic compounds during application and drying processes.This study seeks to enhance the efficiency of Chinese natural paints and increase their accessibility as bio-based alternatives,thereby mitigating the adverse effects of industrial paints on the environment.The researchers incorporated ten materials into the Chinese natural lacquer,with the formulations containing 5%titanium dioxide nanoparticles and 5%polyurethane demonstrating superior performance.These formulations reduced the drying time of the Chinese natural lacquer to 12 hours and 8 hours,respectively,under climatic conditions of 34 degrees Celsius and 64%humidity,while also improving the physical properties of the expanding materials.By experimenting with the materials and processes of contemporary lacquer art,modern lacquer material drying time test,scanning electron microscope(SEM),water droplet angle test,pencil hardness test,adhesion test and other tests,expanding the modern lacquer art materials;the researchers carried out comparative experiments of creative practice,using modern Chinese lacquer materials completely original 32 lacquer paintings,20 of which were successful;the creation of lacquer paintings using the traditional methods The creation cycle of the works using the traditional method was around 2 months,as a control,the creation cycle of the lacquer paintings using the innovative method was between 2 weeks and 3 weeks,which is a drastic reduction in time.Expanded Chinese natural lacquer can contribute to the sustainable development of traditional Chinese lacquer art.展开更多
Along with the surge of unearthed medical literature and cultural relics in recent years,a network of channels in the system of medical conduit vessels(meridians) during the early Western Han dynasty has become much c...Along with the surge of unearthed medical literature and cultural relics in recent years,a network of channels in the system of medical conduit vessels(meridians) during the early Western Han dynasty has become much clearer gradually.In it,the increasing number of channel branches,network vessels and needle insertion holes(acupoints) is an important feature of the development of channel medicine during the Western Han dynasty.This is not only a reflection of the expanding requirements of the theoretical system of the main trunk channels and other vessels,but also an inevitable result of the continuous enrichment and accumulation of clinical experience.This article integrates the information about channel branches,network vessels,inscriptions,dots and further relics on the Tianhui(天回) Lacquered Meridian Figurine to compare the unearthed literature of the channel genre with the transmitted classical literature about acupuncture.The “Heart-Regulated Channel” in Medical Manuscripts on Bamboo Slips from Tianhui(《天回医简》) serves as an example to explain the occurrence,development and changes of the channel branches and network vessels in the early system of medical channels.展开更多
基金financially supported by the Science and Technology Research of Shaanxi Province(2020QFY08-03)Forestry Science and Technology Programs of Shaanxi Province(SXLK2020-0213)supported by the Fundamental Research Funds for the Central Universities(GK202103098)。
文摘The high incidence of postpartum hypogalactia hinders the healthy development of postpartum women and the next generation.Lacquer seed oil(LSO),extracted from the seeds of the lacquer tree,has been traditionally used as a dietary supplement for promoting postpartum lactation and recovery in some districts of China.However,its physiological effects have not been verified,and the mechanism and active components of LSO have not been analyzed.Thus,we applied LSO to bromocriptine-induced postpartum hypogalactia rats.The results showed that LSO supplement effectively improves bromocriptine-induced postpartum hypogalactia.LSO also increased prolactin levels reduced by bromocriptine,promoted JAK2/STAT5 and PI3K/AKT pathways and several gene expression levels of milk synthesis in mammary gland.Moreover,metabolomic and network pharmacological analysis further revealed that JAK2/STAT5,PI3K/AKT,and estrogen signaling pathway are the potential main regulatory sites for the beneficial effects of LSO on postpartum hypogalactia,and that quercetin,kaempferol,arachidonic acid,epicatechin,and β-sitosterol are the top 5 main active ingredients of LSO.Our results suggested that LSO has great potential in the application of the improvement of postpartum hypogalactia.
基金National Key Research and Development Program of China(Nos.2023YFD1702003 and 2023YFC3709001).
文摘This study aims to optimize the use of lacquer residue biomass(LBM).We investigated the ability of LBM to remove Pb^(2+)heavy metal ions and the typical cationic dye methylene blue(MB)and anionic dye Congo red(CR)by simultaneous adsorption from composite systems,as well as the relevant factors.Scanning electron microscopy(SEM),X-ray diffraction(XRD),and Fourier transform infrared spectroscopy(FTIR)were used to characterize adsorption behavior.The adsorption kinetics of Pb^(2+)-MB/CR composite systems can be effectively characterized by the pseudo-second-order kinetic model(R^(2)>0.97).In the Pb^(2+)-MB composite system,adsorption was antagonistic with similar adsorption sites.However,in the Pb^(2+)-CR composite system,we found that adsorption was synergistic with different adsorption sites,which led to a higher simultaneous adsorption capacity for a higher initial Pb^(2+)-CR concentration,unlike the Pb^(2+)-MB system.In both composite systems,an appropriate increase in LBM dosage and system temperature within a certain range was conducive to simultaneous adsorption and removal of Pb^(2+)-MB/CR composite systems.The optimal solid-liquid ratio and temperature were 1:75 and 30℃,respectively.The adsorption and removal rates of Pb^(2+)and MB were 99.98%and 90.49%,respectively,and those of Pb^(2+)and CR were 93.99%and 77.39%,respectively,in(50,50)mg/L of Pb^(2+)-MB/CR composite systems under these conditions.Adsorption removal of Pb^(2+)and MB improved with higher pH levels,and worsened with the increase of ionic strength in the solution,while the removal rate of CR showed an opposite trend.The coexisting anion and cation types had limited influence on the simultaneous adsorption removal of Pb^(2+),MB,and CR.The results of desorption showed that LBM can be utilized as a disposable material for simultaneously treating Pb^(2+)-MB/CR composite systems.The simultaneous adsorption mechanisms of Pb^(2+)-MB/CR mainly involved hydrogen bonding,π-πbonding interaction,and electrostatic interaction.
文摘Industrial paints exacerbate air pollution by emitting volatile organic compounds during application and drying processes.This study seeks to enhance the efficiency of Chinese natural paints and increase their accessibility as bio-based alternatives,thereby mitigating the adverse effects of industrial paints on the environment.The researchers incorporated ten materials into the Chinese natural lacquer,with the formulations containing 5%titanium dioxide nanoparticles and 5%polyurethane demonstrating superior performance.These formulations reduced the drying time of the Chinese natural lacquer to 12 hours and 8 hours,respectively,under climatic conditions of 34 degrees Celsius and 64%humidity,while also improving the physical properties of the expanding materials.By experimenting with the materials and processes of contemporary lacquer art,modern lacquer material drying time test,scanning electron microscope(SEM),water droplet angle test,pencil hardness test,adhesion test and other tests,expanding the modern lacquer art materials;the researchers carried out comparative experiments of creative practice,using modern Chinese lacquer materials completely original 32 lacquer paintings,20 of which were successful;the creation of lacquer paintings using the traditional methods The creation cycle of the works using the traditional method was around 2 months,as a control,the creation cycle of the lacquer paintings using the innovative method was between 2 weeks and 3 weeks,which is a drastic reduction in time.Expanded Chinese natural lacquer can contribute to the sustainable development of traditional Chinese lacquer art.
基金one of the stage results of the Science and Technology Innovation Project (CI2021A00413) of the China Academy of Traditional Chinese Medicine。
文摘Along with the surge of unearthed medical literature and cultural relics in recent years,a network of channels in the system of medical conduit vessels(meridians) during the early Western Han dynasty has become much clearer gradually.In it,the increasing number of channel branches,network vessels and needle insertion holes(acupoints) is an important feature of the development of channel medicine during the Western Han dynasty.This is not only a reflection of the expanding requirements of the theoretical system of the main trunk channels and other vessels,but also an inevitable result of the continuous enrichment and accumulation of clinical experience.This article integrates the information about channel branches,network vessels,inscriptions,dots and further relics on the Tianhui(天回) Lacquered Meridian Figurine to compare the unearthed literature of the channel genre with the transmitted classical literature about acupuncture.The “Heart-Regulated Channel” in Medical Manuscripts on Bamboo Slips from Tianhui(《天回医简》) serves as an example to explain the occurrence,development and changes of the channel branches and network vessels in the early system of medical channels.
