Mpox,formerly known as monkeypox,is a zoonotic virus of the Orthopoxvirus genus,with recent outbreaks of Clade I and Ib in Central Africa presenting a considerable global health threat.This study reviews current Mpox ...Mpox,formerly known as monkeypox,is a zoonotic virus of the Orthopoxvirus genus,with recent outbreaks of Clade I and Ib in Central Africa presenting a considerable global health threat.This study reviews current Mpox immunization approaches,focusing on the MVA-BN,LC16-KMB,and OrthopoxVac vaccines.MVA-BN vaccination has been successful in lowering infection risks,particularly in high-risk individuals and is widely used in the USA.LC16-KMB is recommended by the World Health Organization for prevention in afflicted regions.OrthopoxVac,a newer vaccination authorized in Russia,provides wide protection.Adapting vaccination approaches based on epidemiology in particular areas is critical for minimizing Mpox outbreaks.展开更多
文摘Mpox,formerly known as monkeypox,is a zoonotic virus of the Orthopoxvirus genus,with recent outbreaks of Clade I and Ib in Central Africa presenting a considerable global health threat.This study reviews current Mpox immunization approaches,focusing on the MVA-BN,LC16-KMB,and OrthopoxVac vaccines.MVA-BN vaccination has been successful in lowering infection risks,particularly in high-risk individuals and is widely used in the USA.LC16-KMB is recommended by the World Health Organization for prevention in afflicted regions.OrthopoxVac,a newer vaccination authorized in Russia,provides wide protection.Adapting vaccination approaches based on epidemiology in particular areas is critical for minimizing Mpox outbreaks.