本文针对长基线(long baseline,LBL)声学定位系统中声信标几何构型优化问题,系统分析了克拉默-拉奥下界(Cramer-Rao lower bound,CRLB)、Fisher信息矩阵(Fisher information matrix,FIM)和几何精度因子(geometric dilution of precision...本文针对长基线(long baseline,LBL)声学定位系统中声信标几何构型优化问题,系统分析了克拉默-拉奥下界(Cramer-Rao lower bound,CRLB)、Fisher信息矩阵(Fisher information matrix,FIM)和几何精度因子(geometric dilution of precision,GDOP)三种评价因子的性能特征及应用场景.与雷达/卫星定位不同,水声定位受复杂海洋环境影响显著,本文重点研究了三种评价因子在300 m×300 m监测区域内的应用差异及其在水声环境中的特殊性.结果表明:水声定位受声信标几何构型的影响,导致定位误差模型更为复杂,而CRLB能够更敏感地反映该因素对理论误差下界的影响.FIM在水下定位应用中需结合系统构型分析信息量分布,避免几何构型缺陷导致的信息不均衡问题.几何精度因子(geometric dilution of precision,GDOP)的无量纲特性可直观体现声信标空间分布对定位误差的几何放大效应.本文以此提出多指标联合评估策略:优先采用GDOP进行构型筛选,结合CRLB验证理论极限精度,辅以FIM分析信息量分布特性.弥补了单一指标在水声复杂场景下的局限性.展开更多
Drug-eluting magnesium(Mg)alloy stents have a slower degradation rate and lower restenosis rate compared with uncoated stents,demonstrating good clinical efficacy.However,the release of anti-hyperplasia drugs from coa...Drug-eluting magnesium(Mg)alloy stents have a slower degradation rate and lower restenosis rate compared with uncoated stents,demonstrating good clinical efficacy.However,the release of anti-hyperplasia drugs from coatings delays endothelial tissue repair,thus leading to late stent thrombosis.To address these issues,a dual self-healed coating with various biological properties was fabricated on magnesium fluoride/polydopamine(MgF_(2)/PDA)-treated Mg alloys by spraying-assisted layer-by-layer(LBL)self-assembly of chitosan(CS),gallic acid(GA),and 3-aminobenzeneboronic acid-modified hyaluronic acid(HA-ABBA).The LBL coating,approximately 1.50μm thick,exhibited a uniform morphology with good adhesion strength(~1065 mN).The annual corrosion rate(Pi)of LBL samples was~1400 times slower than that of the Mg substrate,due to the physical barrier function provided by MgF_(2)/PDA layers and the dual self-healed ability of LBL layers.The rapid self-healing ability(with a healing period of~4 h under dynamic/static conditions)resulted from the synergistic interplay between the recombination of diverse chemical bonds within the LBL coating and the coordination of LBL-released GA with Mg2+,as corroborated by computer simulations.Compared with the drug-eluting coatings,the LBL sample demonstrated substantial advantages in anti-oxidation,anti-denaturation of fibrinogen,anti-platelet adhesion,anti-inflammation,anti-hyperplasia,and promoted-endothelialization.These benefits effectively address the limitations associated with drug-eluting coatings.展开更多
Organic solar cells(OSCs)have emerged as promising candidates for next‐generation photovoltaics,yet traditional bulk heterojunction(BHJ)devices face inherent limitations in morphology control and phase separation.La...Organic solar cells(OSCs)have emerged as promising candidates for next‐generation photovoltaics,yet traditional bulk heterojunction(BHJ)devices face inherent limitations in morphology control and phase separation.Layer‐by‐layer(LbL)processing with a p–i–n configuration offers an innovative solution by enabling precise control over donor–acceptor distribution and interfacial characteristics.Here,we systematically investigate nine halogen‐functionalized additives across three categories—methyl halides,thiophene halides,and benzene halides—for optimizing LbL device performance.These additives,distinguished by their diverse thermal properties and solid–liquid transformation capabilities below 100°C,are functionalized as both nucleation centers and morphology‐modulating plasticizers during thermal treatment.Among them,2‐bromo‐5‐iodothiophene(BIT)demonstrates superior performance through synergistic effects of its bromine–iodine combination and thiophene core in mediating donor–acceptor interactions.LbL devices processed with BIT achieve exceptional metrics in the PM6/L8‐BO system,including a open‐circuit voltage of 0.916 V,a short‐circuit current density of 27.12 mA cm−2,and an fill factor of 80.97%,resulting in an impressive power conversion efficiency of 20.12%.This study establishes a molecular design strategy for halogen‐functionalized additives that simultaneously optimizes both donor and acceptor layers while maintaining processing simplicity for potential industrial applications.展开更多
目的为提升医学检验本科生毕业课题实践质量,开题汇报作为毕业论文之始,其考核分析至关重要。方法在开题汇报考核中,针对35名医学检验本科生开题汇报的考核情况,7名学生试点应用讲授式教学法(lecture based learning,LBL)结合问题模式...目的为提升医学检验本科生毕业课题实践质量,开题汇报作为毕业论文之始,其考核分析至关重要。方法在开题汇报考核中,针对35名医学检验本科生开题汇报的考核情况,7名学生试点应用讲授式教学法(lecture based learning,LBL)结合问题模式教学法(problem based learning,PBL)教学,与28名传统教学组相比较,深入剖析研究领域、汇报问题、效果以及带教老师资质和学生反馈等方面。结果开题汇报选题内容与科室特色紧密相关,开题汇报有利于提升学生综合素质,开题效果的提升需师生共同努力;相较于传统教学,LBL结合PBL教学有利于提高开题汇报的质量,且学生认为自己对毕业课题认识更为深入。结论LBL结合PBL教学适用于医学检验本科生毕业论文开题汇报的教学,利于培养医学检验本科生科研素质。展开更多
In the last few years,scholars have continued to refine the understanding of conservatism through cultural psychology.The application of Symbolic Action Theory,particularly Ernst Boesch’s framework,remains central to...In the last few years,scholars have continued to refine the understanding of conservatism through cultural psychology.The application of Symbolic Action Theory,particularly Ernst Boesch’s framework,remains central to discussions,illustrating how conservatism is not merely a political stance but a dynamic system of behaviors that reinforces societal values through symbolic actions(Kölbl,2020).Additionally,recent studies have highlighted the interaction between cultural conservatism and collective identity,with particular focus on how conservatism can manifest in diverse cultural settings(Yilmaz&Alper,2019).Research also underscores the relevance of symbolic politics in shaping both individual attitudes and broader political actions,contributing to the understanding of how symbolic meanings sustain social conservatism in different cultural contexts(Chin&Levey,2022).展开更多
文摘本文针对长基线(long baseline,LBL)声学定位系统中声信标几何构型优化问题,系统分析了克拉默-拉奥下界(Cramer-Rao lower bound,CRLB)、Fisher信息矩阵(Fisher information matrix,FIM)和几何精度因子(geometric dilution of precision,GDOP)三种评价因子的性能特征及应用场景.与雷达/卫星定位不同,水声定位受复杂海洋环境影响显著,本文重点研究了三种评价因子在300 m×300 m监测区域内的应用差异及其在水声环境中的特殊性.结果表明:水声定位受声信标几何构型的影响,导致定位误差模型更为复杂,而CRLB能够更敏感地反映该因素对理论误差下界的影响.FIM在水下定位应用中需结合系统构型分析信息量分布,避免几何构型缺陷导致的信息不均衡问题.几何精度因子(geometric dilution of precision,GDOP)的无量纲特性可直观体现声信标空间分布对定位误差的几何放大效应.本文以此提出多指标联合评估策略:优先采用GDOP进行构型筛选,结合CRLB验证理论极限精度,辅以FIM分析信息量分布特性.弥补了单一指标在水声复杂场景下的局限性.
基金supported by the National Key Research and Development Program of China(No.2021YFC2400703)the Key Scientific and Technological Research Projects in Henan Province(Nos.232102311155 and 232102230106)Zhengzhou University Major Project Cultivation Special Project(No.125-32214076).
文摘Drug-eluting magnesium(Mg)alloy stents have a slower degradation rate and lower restenosis rate compared with uncoated stents,demonstrating good clinical efficacy.However,the release of anti-hyperplasia drugs from coatings delays endothelial tissue repair,thus leading to late stent thrombosis.To address these issues,a dual self-healed coating with various biological properties was fabricated on magnesium fluoride/polydopamine(MgF_(2)/PDA)-treated Mg alloys by spraying-assisted layer-by-layer(LBL)self-assembly of chitosan(CS),gallic acid(GA),and 3-aminobenzeneboronic acid-modified hyaluronic acid(HA-ABBA).The LBL coating,approximately 1.50μm thick,exhibited a uniform morphology with good adhesion strength(~1065 mN).The annual corrosion rate(Pi)of LBL samples was~1400 times slower than that of the Mg substrate,due to the physical barrier function provided by MgF_(2)/PDA layers and the dual self-healed ability of LBL layers.The rapid self-healing ability(with a healing period of~4 h under dynamic/static conditions)resulted from the synergistic interplay between the recombination of diverse chemical bonds within the LBL coating and the coordination of LBL-released GA with Mg2+,as corroborated by computer simulations.Compared with the drug-eluting coatings,the LBL sample demonstrated substantial advantages in anti-oxidation,anti-denaturation of fibrinogen,anti-platelet adhesion,anti-inflammation,anti-hyperplasia,and promoted-endothelialization.These benefits effectively address the limitations associated with drug-eluting coatings.
基金supported by the National Key Research and Development Program of China(Grant No.2022YFB4200500)National Natural Science Foundation of China(NSFC,22379101 and 22422904)Sichuan Natural Science Foundation(2024NSFSC0001 and 2025ZNSFSC0960).
文摘Organic solar cells(OSCs)have emerged as promising candidates for next‐generation photovoltaics,yet traditional bulk heterojunction(BHJ)devices face inherent limitations in morphology control and phase separation.Layer‐by‐layer(LbL)processing with a p–i–n configuration offers an innovative solution by enabling precise control over donor–acceptor distribution and interfacial characteristics.Here,we systematically investigate nine halogen‐functionalized additives across three categories—methyl halides,thiophene halides,and benzene halides—for optimizing LbL device performance.These additives,distinguished by their diverse thermal properties and solid–liquid transformation capabilities below 100°C,are functionalized as both nucleation centers and morphology‐modulating plasticizers during thermal treatment.Among them,2‐bromo‐5‐iodothiophene(BIT)demonstrates superior performance through synergistic effects of its bromine–iodine combination and thiophene core in mediating donor–acceptor interactions.LbL devices processed with BIT achieve exceptional metrics in the PM6/L8‐BO system,including a open‐circuit voltage of 0.916 V,a short‐circuit current density of 27.12 mA cm−2,and an fill factor of 80.97%,resulting in an impressive power conversion efficiency of 20.12%.This study establishes a molecular design strategy for halogen‐functionalized additives that simultaneously optimizes both donor and acceptor layers while maintaining processing simplicity for potential industrial applications.
文摘目的为提升医学检验本科生毕业课题实践质量,开题汇报作为毕业论文之始,其考核分析至关重要。方法在开题汇报考核中,针对35名医学检验本科生开题汇报的考核情况,7名学生试点应用讲授式教学法(lecture based learning,LBL)结合问题模式教学法(problem based learning,PBL)教学,与28名传统教学组相比较,深入剖析研究领域、汇报问题、效果以及带教老师资质和学生反馈等方面。结果开题汇报选题内容与科室特色紧密相关,开题汇报有利于提升学生综合素质,开题效果的提升需师生共同努力;相较于传统教学,LBL结合PBL教学有利于提高开题汇报的质量,且学生认为自己对毕业课题认识更为深入。结论LBL结合PBL教学适用于医学检验本科生毕业论文开题汇报的教学,利于培养医学检验本科生科研素质。
基金supported by the Philosophy and Social Science Research Fund of Zhejiang Province(Grant No.24ZJQN095YB)the Educational and Teaching Reform Project of HDU-ITMO Joint Institute(Grant No.SGJ2023JG007).
文摘In the last few years,scholars have continued to refine the understanding of conservatism through cultural psychology.The application of Symbolic Action Theory,particularly Ernst Boesch’s framework,remains central to discussions,illustrating how conservatism is not merely a political stance but a dynamic system of behaviors that reinforces societal values through symbolic actions(Kölbl,2020).Additionally,recent studies have highlighted the interaction between cultural conservatism and collective identity,with particular focus on how conservatism can manifest in diverse cultural settings(Yilmaz&Alper,2019).Research also underscores the relevance of symbolic politics in shaping both individual attitudes and broader political actions,contributing to the understanding of how symbolic meanings sustain social conservatism in different cultural contexts(Chin&Levey,2022).
