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基于临床基础指标、LAAeV、LAAfV、LAAV构建卵圆孔未闭患者并发房颤的列线图模型
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作者 杜利军 王俊伟 王旭 《四川医学》 CAS 2024年第10期1073-1078,共6页
目的探讨临床基础指标、左心耳(LAA)最大排空速度(LAAeV)、LAA最大充盈速度(LAAfV)、LAA容积(LAAV)与卵圆孔未闭患者并发房颤关系,以期指导个体化诊治。方法收集2020年1月至2022年6月我院收治的176例卵圆孔未闭患者临床资料,根据卵圆孔... 目的探讨临床基础指标、左心耳(LAA)最大排空速度(LAAeV)、LAA最大充盈速度(LAAfV)、LAA容积(LAAV)与卵圆孔未闭患者并发房颤关系,以期指导个体化诊治。方法收集2020年1月至2022年6月我院收治的176例卵圆孔未闭患者临床资料,根据卵圆孔未闭出院后1年是否并发房颤分为房颤组(n=26)和非房颤组(n=150),比较两组临床基础指标、LAAeV、LAAfV、LAAV,采用Logistic回归方程分析卵圆孔未闭并发房颤影响因素,构建列线图模型,采用受试者工作特征曲线(ROC)、校准曲线、净重新分类指数(NRI)、综合判别改善指数(IDI)评价列线图模型区分度、校准度、改进能力。结果两组年龄、高血压、介入封堵术、LMR、hsCRP、TNF-α、IL-6、LAAeV、LAAfV、LAAVmin、LAAVmax比较差异有统计学意义(P<0.05);Logistic回归方程显示,年龄、高血压、介入封堵术、LMR、IL-6、LAAeV、LAAVmin、LAAVmax、LAAfV是卵圆孔未闭患者并发房颤影响因素(OR=4.725、6.077、5.348、4.054、4.449、0.596、5.189、4.077、0.653,95%CI=1.485~15.031、2.240~16.487、1.612~17.744、1.345~12.217、1.278~15.491、0.452~0.786、1.669~16.131、1.155~14.389、0.503~0.847,P<0.05);基于Logistic回归方程筛选影响因素构建卵圆孔未闭合并房颤的列线图模型AUC为0.872(95%CI 0.850~0.913),NRI、IDI分别为0.550、0.088,且校准曲线与理想曲线较为贴合。结论基于临床基础指标、LAAeV、LAAfV、LAAVmin、LAAVmax构建卵圆孔未闭并发房颤列线图模型具有较好预测性能,可为临床治疗提供新思路。 展开更多
关键词 卵圆孔未闭 房颤 临床基础指标 LAAeV LAAfV laav
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Advanced hybrid machine learning models combined with petrographic analysis for comprehensive durability assessment of rock construction materials
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作者 Javid Hussain Xiaodong Fu +4 位作者 Jian Chen Nafees Ali Jabir Hussain Sartaj Hussain Sabir Ali 《Intelligent Geoengineering》 2025年第4期216-235,共20页
Durable aggregates are essential for the stability and longevity of construction projects,and the Los Angeles Abrasion(LAA)value is a widely used indicator of aggregate durability.However,direct LAA testing is time-co... Durable aggregates are essential for the stability and longevity of construction projects,and the Los Angeles Abrasion(LAA)value is a widely used indicator of aggregate durability.However,direct LAA testing is time-consuming,costly,and requires specialized facilities.This study introduces a novel and efficient alternative by developing two hybrid machine learning models Artificial Neural Network integrated with Particle Swarm Optimization(ANN-PSO)and Artificial Neural Network combined with Teaching-Learning-Based Optimization(ANN-TLBO)for the first time to predict LAA values from petrographic characteristics of carbonate rocks.A total of 160 rock samples from 10 geological formations in Pakistan’s Salt Range were analyzed through petrographic examination and LAA testing.The predictive performance of the proposed models was compared with established techniques,including Multiple Linear Regression,Random Forest,Adaptive Boosting,Gradient Boosting,K-Nearest Neighbors,and Multilayer Perceptron.Results demonstrate that ANN-PSO significantly outperformed all other approaches,achieving an R^(2)of 0.9982,RMSE of 0.209,MAE of 0.159,and MAPE of 0.009.Model robustness was validated using Taylor plots,REC curves,and an external dataset.Sensitivity analysis identified quartz,calcite,and feldspar as the most influential factors affecting LAA prediction.The findings confirm that the ANN-PSO and ANN-TLBO models provide highly accurate,cost-effective,and practical alternatives to traditional LAA testing.This innovative approach advances rock mechanics and material assessment,offering engineers and geologists enhanced tools for aggregate selection and durability evaluation in infrastructure projects. 展开更多
关键词 ANN-PSO Carbonate rocks laav Sensitivity analyses Petrographic analyses
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