The interaction between nanoparticles (NPs) and pollutants affects their bioavailability and toxicity.However,the processes by which NPs and pollutants change in vivo have rarely been explored.Here,using laser ablatio...The interaction between nanoparticles (NPs) and pollutants affects their bioavailability and toxicity.However,the processes by which NPs and pollutants change in vivo have rarely been explored.Here,using laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS),we found that both nanoplastics and ZnO NPs caused more Cd to accumulate in zebrafish larvae,but with distinct pathways.Nanoplastics could adsorb Cd^(2+) and transfer it into the larvae through the“Trojan horse”effect.The coexposure of nanoplastics and Cd^(2+) caused Cd to accumulate in the abdomen where the nanoplastics were located without dissociation,showing a lower toxic effect than Cd^(2+) exposure alone.ZnO NPs weakly adsorbed Cd^(2+),but they increased the Zn and Cd contents in larvae by enhancing the expression of metal transporters.The coexposure of ZnO and Cd^(2+) evenly distributed Cd in the larvae,revealing a more severe toxic effect than Cd^(2+) exposure alone.Our results demonstrated the changing bioavailability and toxicity of Cd induced by different NPs.This also shows the vital role LA-ICP-MS plays in revealing the relationship between toxicity and bioavailability.In addition,the long-term effect of bioavailability on heavy metal toxicity and nanosafety deserves further investigation.展开更多
Due to the limitations of widely used energy spectrum and spectral analyses for the determination of trace elements in coal,the modes of occurrence of Li still remains unclear.This study investigated the distribution ...Due to the limitations of widely used energy spectrum and spectral analyses for the determination of trace elements in coal,the modes of occurrence of Li still remains unclear.This study investigated the distribution of Li in selected bulk samples and in-situ kaolinite particles in the No.6 Li-rich coals from the Haerwusu Mine of the Jungar Coalfield using ICP-MS and LA-ICP-MS.The results reveal an elevated Li concentration in the lower section of the No.6 coal with high Sr/Ba ratio compared to the upper section with more terrigenous mudstone along the vertical profile.LA-ICP-MS mapping and spot analyses results showed that Li was concentrated in kaolinite but occur in variations in the concentrations of Li among different types of kaolinite.The concentration of Li in kaolinite is ranked as follows:cryptocrystalline kaolinite(2225.83 ppm)>vermicular kaolinite(651.49 ppm)>altered K-bearing kaolinite(593.44 ppm)>clastic kaolinite(478.68 ppm).The in-situ concentration of Li in kaolinite is much higher than that of the bulk samples,indicating that kaolinite is the dominant host mineral for Li as well.The Al2O3/TiO2 and Nb/Yb-Zr/TiO2 ratios indicate that Li in No.6 coal primarily originated from Paleoproterozoic granite in the Yinshan Mountain and felsic volcanic ash.Seawater leaching has a critical influence on the redistribution of Li in the coal from the Haerwusu Mine or even the whole Jungar Coalfield.展开更多
基金financially supported by the National Natural Science Foundation of China(NSFC,Nos.22174103 and 21575107)。
文摘The interaction between nanoparticles (NPs) and pollutants affects their bioavailability and toxicity.However,the processes by which NPs and pollutants change in vivo have rarely been explored.Here,using laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS),we found that both nanoplastics and ZnO NPs caused more Cd to accumulate in zebrafish larvae,but with distinct pathways.Nanoplastics could adsorb Cd^(2+) and transfer it into the larvae through the“Trojan horse”effect.The coexposure of nanoplastics and Cd^(2+) caused Cd to accumulate in the abdomen where the nanoplastics were located without dissociation,showing a lower toxic effect than Cd^(2+) exposure alone.ZnO NPs weakly adsorbed Cd^(2+),but they increased the Zn and Cd contents in larvae by enhancing the expression of metal transporters.The coexposure of ZnO and Cd^(2+) evenly distributed Cd in the larvae,revealing a more severe toxic effect than Cd^(2+) exposure alone.Our results demonstrated the changing bioavailability and toxicity of Cd induced by different NPs.This also shows the vital role LA-ICP-MS plays in revealing the relationship between toxicity and bioavailability.In addition,the long-term effect of bioavailability on heavy metal toxicity and nanosafety deserves further investigation.
基金supported by the National Key R&D Program of China(No.2021YFC2902003)National Natural Science Foundation of China(No.42302193No.42272201).
文摘Due to the limitations of widely used energy spectrum and spectral analyses for the determination of trace elements in coal,the modes of occurrence of Li still remains unclear.This study investigated the distribution of Li in selected bulk samples and in-situ kaolinite particles in the No.6 Li-rich coals from the Haerwusu Mine of the Jungar Coalfield using ICP-MS and LA-ICP-MS.The results reveal an elevated Li concentration in the lower section of the No.6 coal with high Sr/Ba ratio compared to the upper section with more terrigenous mudstone along the vertical profile.LA-ICP-MS mapping and spot analyses results showed that Li was concentrated in kaolinite but occur in variations in the concentrations of Li among different types of kaolinite.The concentration of Li in kaolinite is ranked as follows:cryptocrystalline kaolinite(2225.83 ppm)>vermicular kaolinite(651.49 ppm)>altered K-bearing kaolinite(593.44 ppm)>clastic kaolinite(478.68 ppm).The in-situ concentration of Li in kaolinite is much higher than that of the bulk samples,indicating that kaolinite is the dominant host mineral for Li as well.The Al2O3/TiO2 and Nb/Yb-Zr/TiO2 ratios indicate that Li in No.6 coal primarily originated from Paleoproterozoic granite in the Yinshan Mountain and felsic volcanic ash.Seawater leaching has a critical influence on the redistribution of Li in the coal from the Haerwusu Mine or even the whole Jungar Coalfield.
