For a class of fractional-order linear continuous-time switched systems specified by an arbitrary switching sequence,the performance of PDα-type fractional-order iterative learning control(FOILC)is discussed in the s...For a class of fractional-order linear continuous-time switched systems specified by an arbitrary switching sequence,the performance of PDα-type fractional-order iterative learning control(FOILC)is discussed in the sense of L^p norm.When the systems are disturbed by bounded external noises,robustness of the PDα-type algorithm is firstly analyzed in the iteration domain by taking advantage of the generalized Young inequality of convolution integral.Then,convergence of the algorithm is discussed for the systems without any external noise.The results demonstrate that,under some given conditions,both convergence and robustness can be guaranteed during the entire time interval.Simulations support the correctness of the theory.展开更多
目的:建立高效液相色谱(HPLC)指纹图谱与一测多评(QAMS)结合的方法同时检测一枝蒿Artemisia rupestris L.药材中新绿原酸、绿原酸、隐绿原酸、异绿原酸B、异绿原酸A、异绿原酸C、蒙花苷、一枝蒿酮酸、金腰乙素、艾黄素含量,并建立不同...目的:建立高效液相色谱(HPLC)指纹图谱与一测多评(QAMS)结合的方法同时检测一枝蒿Artemisia rupestris L.药材中新绿原酸、绿原酸、隐绿原酸、异绿原酸B、异绿原酸A、异绿原酸C、蒙花苷、一枝蒿酮酸、金腰乙素、艾黄素含量,并建立不同产地一枝蒿药材的综合质量评价模型,为一枝蒿药材的整体质量评价提供参考。方法:采用HPLC法测定不同产地15批次一枝蒿药材的指纹图谱,色谱柱为YMC-Pack ODS-A C_(18)(250 mm×4.6 mm,5μm),以乙腈-0.2%甲酸溶液为流动相,梯度洗脱,分段变波长检测,柱温30℃,体积流量1.0 m L·min^(-1)。利用聚类分析、主成分分析(PCA)和正交偏最小二乘判别分析(OPLS-DA)对采集的指纹图谱信息进行分析,同时运用熵权逼近理想解排序(technique for order preference by similarity to ideal solution,TOPSIS)法、加权秩和比(rank sum ratio,RSR)法及两者模糊联合的方法构建评价模型;以蒙花苷为内标,确定新绿原酸、绿原酸、隐绿原酸、异绿原酸B、异绿原酸A、异绿原酸C、一枝蒿酮酸、金腰乙素、艾黄素的相对校正因子并计算其含量,建立QAMS法。结果:建立的一枝蒿药材指纹图谱共标定18个共有峰,指认出其中11个峰。化学计量学模式研究显示不同产地一枝蒿药材存在明显差异。通过OPLS-DA法筛选出11个主要的差异性成分。构建的熵权TOPSIS法、加权RSR法以及二者模糊联合的综合质量评价模型,对不同产地一枝蒿药材的质量评价排序结果较为一致。10个定量成分线性关系均良好(r≥0.9990),平均加样回收率92.6%~107.2%,RSD均<3.0%。以蒙花苷为内标建立的QAMS和外标法含量测定结果无显著性差异(P>0.05)。结论:所建立的HPLC指纹图谱结合QAMS法简便可靠,重复性好;建立的综合质量评价模型的分析结果全面客观,可用于一枝蒿药材整体质量的综合评价。展开更多
基金supported by the National Natural Science Foundation of China(61201323)the Special Fund Project for Promoting Scientific and Technological Innovation in Xuzhou City(KC18013)the Cultivation Project of Xuzhou Institute of Technology(XKY2017112)
文摘For a class of fractional-order linear continuous-time switched systems specified by an arbitrary switching sequence,the performance of PDα-type fractional-order iterative learning control(FOILC)is discussed in the sense of L^p norm.When the systems are disturbed by bounded external noises,robustness of the PDα-type algorithm is firstly analyzed in the iteration domain by taking advantage of the generalized Young inequality of convolution integral.Then,convergence of the algorithm is discussed for the systems without any external noise.The results demonstrate that,under some given conditions,both convergence and robustness can be guaranteed during the entire time interval.Simulations support the correctness of the theory.
文摘目的:建立高效液相色谱(HPLC)指纹图谱与一测多评(QAMS)结合的方法同时检测一枝蒿Artemisia rupestris L.药材中新绿原酸、绿原酸、隐绿原酸、异绿原酸B、异绿原酸A、异绿原酸C、蒙花苷、一枝蒿酮酸、金腰乙素、艾黄素含量,并建立不同产地一枝蒿药材的综合质量评价模型,为一枝蒿药材的整体质量评价提供参考。方法:采用HPLC法测定不同产地15批次一枝蒿药材的指纹图谱,色谱柱为YMC-Pack ODS-A C_(18)(250 mm×4.6 mm,5μm),以乙腈-0.2%甲酸溶液为流动相,梯度洗脱,分段变波长检测,柱温30℃,体积流量1.0 m L·min^(-1)。利用聚类分析、主成分分析(PCA)和正交偏最小二乘判别分析(OPLS-DA)对采集的指纹图谱信息进行分析,同时运用熵权逼近理想解排序(technique for order preference by similarity to ideal solution,TOPSIS)法、加权秩和比(rank sum ratio,RSR)法及两者模糊联合的方法构建评价模型;以蒙花苷为内标,确定新绿原酸、绿原酸、隐绿原酸、异绿原酸B、异绿原酸A、异绿原酸C、一枝蒿酮酸、金腰乙素、艾黄素的相对校正因子并计算其含量,建立QAMS法。结果:建立的一枝蒿药材指纹图谱共标定18个共有峰,指认出其中11个峰。化学计量学模式研究显示不同产地一枝蒿药材存在明显差异。通过OPLS-DA法筛选出11个主要的差异性成分。构建的熵权TOPSIS法、加权RSR法以及二者模糊联合的综合质量评价模型,对不同产地一枝蒿药材的质量评价排序结果较为一致。10个定量成分线性关系均良好(r≥0.9990),平均加样回收率92.6%~107.2%,RSD均<3.0%。以蒙花苷为内标建立的QAMS和外标法含量测定结果无显著性差异(P>0.05)。结论:所建立的HPLC指纹图谱结合QAMS法简便可靠,重复性好;建立的综合质量评价模型的分析结果全面客观,可用于一枝蒿药材整体质量的综合评价。
