In the words of the late Sir Colin Blakemore,neurologists have historically sought to infer brain functions in a manner akin to to king a hammer to a computeranalyzing localized anatomical lesions caused by trauma,tum...In the words of the late Sir Colin Blakemore,neurologists have historically sought to infer brain functions in a manner akin to to king a hammer to a computeranalyzing localized anatomical lesions caused by trauma,tumors,or strokes,noting deficits,and inferring what functions certain brain regions may be responsible for.This approach exemplifies a deletion heuristic,where the absence of a specific function reveals insights about the underlying structures or mechanisms responsible for it.By observing what is lost when a particular brain region is damaged,throughout the history of the field,neurologists have pieced together the intricate relationship between anatomy and function.展开更多
L-茶氨酸(L-Theanine,LTA)是茶叶中独特的游离氨基酸,是茶汤鲜爽味的主要来源,具有多种生物活性,属于新食品原料。本文基于Citespace和VOSviewer对Web of Science核心数据库和中国知网数据库,对2014~2024年LTA相关文献进行可视化分析,...L-茶氨酸(L-Theanine,LTA)是茶叶中独特的游离氨基酸,是茶汤鲜爽味的主要来源,具有多种生物活性,属于新食品原料。本文基于Citespace和VOSviewer对Web of Science核心数据库和中国知网数据库,对2014~2024年LTA相关文献进行可视化分析,其中关键词密度和贡献图谱结果显示LTA相关研究集中在茶叶类型、胁迫反应、LTA的生物活性等方面。因此,本文综述了茶叶LTA含量的影响因素,并重点阐述LTA生物活性作用机制,包括抗氧化、抗热应激、抗抑郁、调节代谢、抗癌、调节免疫、调节肠道菌群、保护神经系统、保护肝脏和保护肠道的作用机制,发现LTA主要通过调控核因子κB(Nuclear factor kappa B,NF-κB)、c-Jun氨基末端激酶(c-Jun N-terminal kinase,JNK)、信号传导及转录激活因子(Signal transducer and activator of transcription,STAT)和丝裂原活化蛋白激酶(Mitogen-activated protein kinase,MAPK)等信号通路发挥生物活性功能,并总结了当前LTA在食品产业中的实际应用。本文可为LTA的研究和发展提供方向,并为开发LTA功能性食品提供一定的参考。展开更多
文摘In the words of the late Sir Colin Blakemore,neurologists have historically sought to infer brain functions in a manner akin to to king a hammer to a computeranalyzing localized anatomical lesions caused by trauma,tumors,or strokes,noting deficits,and inferring what functions certain brain regions may be responsible for.This approach exemplifies a deletion heuristic,where the absence of a specific function reveals insights about the underlying structures or mechanisms responsible for it.By observing what is lost when a particular brain region is damaged,throughout the history of the field,neurologists have pieced together the intricate relationship between anatomy and function.
文摘L-茶氨酸(L-Theanine,LTA)是茶叶中独特的游离氨基酸,是茶汤鲜爽味的主要来源,具有多种生物活性,属于新食品原料。本文基于Citespace和VOSviewer对Web of Science核心数据库和中国知网数据库,对2014~2024年LTA相关文献进行可视化分析,其中关键词密度和贡献图谱结果显示LTA相关研究集中在茶叶类型、胁迫反应、LTA的生物活性等方面。因此,本文综述了茶叶LTA含量的影响因素,并重点阐述LTA生物活性作用机制,包括抗氧化、抗热应激、抗抑郁、调节代谢、抗癌、调节免疫、调节肠道菌群、保护神经系统、保护肝脏和保护肠道的作用机制,发现LTA主要通过调控核因子κB(Nuclear factor kappa B,NF-κB)、c-Jun氨基末端激酶(c-Jun N-terminal kinase,JNK)、信号传导及转录激活因子(Signal transducer and activator of transcription,STAT)和丝裂原活化蛋白激酶(Mitogen-activated protein kinase,MAPK)等信号通路发挥生物活性功能,并总结了当前LTA在食品产业中的实际应用。本文可为LTA的研究和发展提供方向,并为开发LTA功能性食品提供一定的参考。
