BACKGROUND The ABCD stratification[combination of serum pepsinogen(PG)levels and titers of antibody(immunoglobulin G,IgG)against Helicobacter pylori(H.pylori)]is effective for the classification of individuals at risk...BACKGROUND The ABCD stratification[combination of serum pepsinogen(PG)levels and titers of antibody(immunoglobulin G,IgG)against Helicobacter pylori(H.pylori)]is effective for the classification of individuals at risk of developing gastric cancer(GC).The Kita–Kyushu lung cancer antigen-1(KK-LC-1)is a Cancer/Testis antigen frequently expressed in GC.AIM To evaluate the effectiveness of KK-LC-1 and ABCD stratification in the diagnosis of GC.METHODS We analyzed the gene expression of KK-LC-1 in surgical specimens obtained from GC tumors.The levels of serum PG I/PG II and IgG against H.pylori were measured.According to their serological status,the patients were classified into the four groups of the ABCD stratification.RESULTS Of the 77 examined patients,63(81.8%)expressed KK-LC-1.The IgG titers of H.pylori and PG II were significantly higher in patients expressing KK-LC-1 than those measured in patients not expressing KK-LC-1(P=0.0289 and P=0.0041,respectively).The expression of KK-LC-1 in group C[PG method(+)/H.pylori infection(+)]was as high as 93.9%high.KK-LC-1 was also detected in group A[-/-].CONCLUSION The KK-LC-1 expression in GC was associated with H.pylori infection and atrophic status,so that,KK-LC-1 may be a useful marker for the diagnosis of GC.展开更多
Based on the published data of structure geology,geochronology,petrology and isotope geochemistry,the authors of this paper have conducted studies on the tectonic evolution history of Japan arc system and Kyushu-Palau...Based on the published data of structure geology,geochronology,petrology and isotope geochemistry,the authors of this paper have conducted studies on the tectonic evolution history of Japan arc system and Kyushu-Palau ridge（KPR） . The studies show that the initial Japan arc system was resulted from the subduction of ancient Pacific plate beneath Eurasian Plate in Permian. It was part of an Andean-type continental volcanic arc which occurred in the offshore in the east of Asian during late Mesozoic era. The formation of tertiary back-arc basin（Japan Sea） resulted in the fundamental tectonic framework of the present arc system. Since Quaternary the system has been lying at E-W compression tectonic setting due to the eastward subduction of Amur Plate. It is expected that Japan arc system will be juxtaposed with Asian continent,which is similar to the present Taiwan arc system. The origin of Philippine Sea Plate（PSP） is still in debate. Some studies argued that it is a trapped oceanic crust segment,while the others insisted that it is a back-arc basin accompanied with ancient IBM arc. However,it is all agreed that the tectonic evolution of PSP started since 50 Ma,i.e.,PSP has drifted from the site around equator at 50 Ma to the present site,and the subduction of PSP along Nankai trough-Ryukyu Trench beneath the Japan arc system during 6–2 Ma led to the formation of the present Ryukyu arc system. Of the PSP,the KPR has been found with the oldest rocks formed at 38 Ma. Combining with its geochemical characteristics of oceanic arc tholeiite,it is suggested that KPR is an intraoceanic volcanic arc,more specifically,a relic arc（i.e.,rear arc of the ancient IBM） after rifting of ancient IBM. In addition,Amami-Daito province is of arc tectonic affinity,but has been affected by mantle plume. Therefore,based on their respective tectonic evolution history and geochemical characteristics of rock samples,it is inferred that there is no genetic relationship between Japan arc system and KPR. It is noted that rocks reflecting continental crust basement feature have been collected on the northern tip of KPR,which may be related to the process of KPR accreting on Japan arc,but the arc-continent accretion process are still at initial stage of modern continental crust accretion model. However,due to the scarcity of data of the northern tip of KPR,crustal structure of this location and its adjacent Nankai trough need to be further constrained by geophysical studies in the future.展开更多
The Philippine Basin,surrounded by a series of oceanic trenches,is an independent deep ocean basin in the West Pacific Ocean.Its middle part is divided into three marginal sea sub-basins by the Kyushu-Palau and West M...The Philippine Basin,surrounded by a series of oceanic trenches,is an independent deep ocean basin in the West Pacific Ocean.Its middle part is divided into three marginal sea sub-basins by the Kyushu-Palau and West Mariana Ridges,namely,the West Philippine Basin,the Shikoku and Parece Vela Basins and the Mariana Trough.This paper,through the analysis of the geomorphologic features and gravity and magnetic characteristics of the basin and identification of striped magnetic anomalies,suggests that the entire Philippine Basin developed magnetic lineation of oceanic nature,and therefore,the entire basin is of the nature of oceanic crust.The basin has developed a series of special geomorphic units with different shapes.The KPR runs through the entire Philippine Basin.From the view of geomorphologic features,the KPR is a discontinuous seamount chain （chain-shaped seamounts） and subduction beneath the Japanese Island arc at the Nankai Trough which is the natural boundary between the basin and the Japanese Island arc.At the positions of 25 N,24 N,23 N and 18 N,obvious discontinuity is shown,which belongs to natural topographic discontinuity.Therefore,the KPR is topographically discontinuous.展开更多
The time series of coordinates of a large number of GPS stations in the world,processed by Prof. Geoffrey Blewitt with GIPSY software are available at http://geodesy. unr. edu.Based on the time series of coordinates i...The time series of coordinates of a large number of GPS stations in the world,processed by Prof. Geoffrey Blewitt with GIPSY software are available at http://geodesy. unr. edu.Based on the time series of coordinates in the global reference frame of IGS08 at more than250 stations of continuous GPS observations,downloaded from the website,the co-seismic displacements of the M7. 3 Kyushu earthquake on April 16,2016 in Japan and the preseismic strain accumulations and displacements in the regional reference frame were obtained. The station of continuous GPS observation at BJFS near Beijing has been quite stable in displacement in the eastern part of China for more than 17 years since the beginning of its operation,and this station is used as the core station in the regional reference frame for the pre-seismic displacement of the Kyushu earthquake of M7. 3. The main feature of the pre-seismic displacements of the Kyushu earthquake is characterized by locking in the crust at and near the epicenter. The anomalous pre-seismic strain accumulation developed in an area of anomalous accumulation of the shear strain component of γ1 on the northeast side of the epicenter,with increasing size of the area and increasing magnitude in γ1. The largest area covered by the anomalous γ1 is about 2000 km2. The change in the E component at BJFS since November 26,2015 was caused by the replacement of the receiver and the antenna at the station. In order to study the shortterm change in displacements at stations at and near the epicenter,the time series at 3 stations with continuous GPS observations,2 at SUWN and DAEJ in south Korea and 1 at BJSH near Beijing were analyzed. The analysis shows that the displacements at the 3 stations have been quite stable in the same manner in east Asia. Thus,BJSH is used as the core station in the regional reference frame of displacement and the displacement time series show that there were no significant short term anomalies before the earthquake.展开更多
In this paper, the Global Satellite Mapping of Precipitation Moving Vector with Kalman filter (GSMaP_MVK) was evaluated and corrected at daily time scales with a spatial resolution of 0.1°;latitude/longitude. The...In this paper, the Global Satellite Mapping of Precipitation Moving Vector with Kalman filter (GSMaP_MVK) was evaluated and corrected at daily time scales with a spatial resolution of 0.1°;latitude/longitude. The reference data came from thirty-four rain gauges on Kyushu Island, Japan. This study focused on the GSMaP_MVK’s ability to detect heavy rainfall patterns that may lead to flooding. Statistical analysis was used to evaluate the GSMaP_MVK data both quantitatively and qualitatively. The statistical analysis included the relative bias (B), the mean error (E), the Nash-Sutcliffe coefficient (CNS), the Root Mean Square Error (RMSE) and the correlation coefficient (r). In addition, Generalized Additive Models (GAMs) were used to conduct GSMaP_MVK data correction. The results of these analyses indicate that GSMaP_MVK data have lower values than observed data and may be significantly underestimated during heavy rainfall. By applying GAM to bias correction, GSMaP_MVK’s ability to detect heavy rainfall was improved. In addition, GAM for bias correction could effectively be applied for significant underestimates of GSMaP_ MVK (i.e., bias of more than 55%). GAM is a new approach to predict rainfall amount for flood and landslide monitoring of satellite base precipitation, especially in areas where rain gauge data are limited.展开更多
The 1975 Haicheng Ms7.3 earthquake affected whole Korean Peninsula and even Kyushu, Japan. In this paper isoseismal map of this earthquake was drawn for these areas by sorting out and analyzing data systematically col...The 1975 Haicheng Ms7.3 earthquake affected whole Korean Peninsula and even Kyushu, Japan. In this paper isoseismal map of this earthquake was drawn for these areas by sorting out and analyzing data systematically collected, furthermore, the characteristics of the earthquake damage were discussed. In the northern Korean Peninsula, the intensity is V in great majority of this area except local area with intensity VI, and the damage is basically in accordance with typical characteristics of corresponding intensity grade. In the southern Korean Peninsula, the intensity is IV in large part of the area, however, in some big cities such as Seoul etc., not only high buildings shook strongly, but also some people appeared perceptions such as feeling dizzy and so on, and electrical service was interrupted on one or two districts because of transformer tripping. These phenomena could be caused by the effect of long-period wave generated from a large earthquake on far-field.展开更多
The 4th International Symposium on‘Gondwana to Asia’was held in Fukuoka,Japan from 8 to 10 November,2007.After the symposium,a field excursion was held in the Kyushu Island,which started from Fukuoka city(Figure 1)o...The 4th International Symposium on‘Gondwana to Asia’was held in Fukuoka,Japan from 8 to 10 November,2007.After the symposium,a field excursion was held in the Kyushu Island,which started from Fukuoka city(Figure 1)on the 11 November 2007 and lasted three days until the 13th.The excursion was led by M.Owada,A.Kamei,K.Watanabe and Y.Osanai.Twenty-one geologists from fifteen countries,including Australia,Brazil,France,Germany,India,Italy,Japan,Russia,Sri Lanka,South Africa,South Korea,Thailand,UK.,USA.and Vietnam participated,making a longitudinal traverse covering most part of Kyushu(Figure 1),and enabling the participants to observe pre-Tertiary basement terranes of the Japanese islands which are interpreted in the global tectonic framework of eastern Asiatic continent and Gondwanaland,and the Pleistocene Aso volcanoes and gold mineralization of the Hishikari Gold Mine(Figure 1).On the first day,the participants stayed in the Jigoku Onsen(spa)of the Aso area and on the second day at Yuno-Onsen(spa)in the Hishikari area.About ten localities(Figure 1)were visited during the excursion.展开更多
基金Supported by Grant-in-Aid for research by the Kitasato University Medical Center,No.H26-008the JSPS KAKENHI,No.17K16578+3 种基金the JSPS KAKENHI,No.26670609Takeda Science FoundationKitasato University Research Grant for Young ResearchersGrant-in-Aid for research from the Kitasato University Medical Center,No.H25-0006
文摘BACKGROUND The ABCD stratification[combination of serum pepsinogen(PG)levels and titers of antibody(immunoglobulin G,IgG)against Helicobacter pylori(H.pylori)]is effective for the classification of individuals at risk of developing gastric cancer(GC).The Kita–Kyushu lung cancer antigen-1(KK-LC-1)is a Cancer/Testis antigen frequently expressed in GC.AIM To evaluate the effectiveness of KK-LC-1 and ABCD stratification in the diagnosis of GC.METHODS We analyzed the gene expression of KK-LC-1 in surgical specimens obtained from GC tumors.The levels of serum PG I/PG II and IgG against H.pylori were measured.According to their serological status,the patients were classified into the four groups of the ABCD stratification.RESULTS Of the 77 examined patients,63(81.8%)expressed KK-LC-1.The IgG titers of H.pylori and PG II were significantly higher in patients expressing KK-LC-1 than those measured in patients not expressing KK-LC-1(P=0.0289 and P=0.0041,respectively).The expression of KK-LC-1 in group C[PG method(+)/H.pylori infection(+)]was as high as 93.9%high.KK-LC-1 was also detected in group A[-/-].CONCLUSION The KK-LC-1 expression in GC was associated with H.pylori infection and atrophic status,so that,KK-LC-1 may be a useful marker for the diagnosis of GC.
基金The China Ocean Mineral Resources R & D Association (COMRA),The Basic Research Project of the Ministryof Science and Technology under contract No. 2008 FY220300the National Natural Science Foundation of China undercontract No. 40609034
文摘Based on the published data of structure geology,geochronology,petrology and isotope geochemistry,the authors of this paper have conducted studies on the tectonic evolution history of Japan arc system and Kyushu-Palau ridge（KPR） . The studies show that the initial Japan arc system was resulted from the subduction of ancient Pacific plate beneath Eurasian Plate in Permian. It was part of an Andean-type continental volcanic arc which occurred in the offshore in the east of Asian during late Mesozoic era. The formation of tertiary back-arc basin（Japan Sea） resulted in the fundamental tectonic framework of the present arc system. Since Quaternary the system has been lying at E-W compression tectonic setting due to the eastward subduction of Amur Plate. It is expected that Japan arc system will be juxtaposed with Asian continent,which is similar to the present Taiwan arc system. The origin of Philippine Sea Plate（PSP） is still in debate. Some studies argued that it is a trapped oceanic crust segment,while the others insisted that it is a back-arc basin accompanied with ancient IBM arc. However,it is all agreed that the tectonic evolution of PSP started since 50 Ma,i.e.,PSP has drifted from the site around equator at 50 Ma to the present site,and the subduction of PSP along Nankai trough-Ryukyu Trench beneath the Japan arc system during 6–2 Ma led to the formation of the present Ryukyu arc system. Of the PSP,the KPR has been found with the oldest rocks formed at 38 Ma. Combining with its geochemical characteristics of oceanic arc tholeiite,it is suggested that KPR is an intraoceanic volcanic arc,more specifically,a relic arc（i.e.,rear arc of the ancient IBM） after rifting of ancient IBM. In addition,Amami-Daito province is of arc tectonic affinity,but has been affected by mantle plume. Therefore,based on their respective tectonic evolution history and geochemical characteristics of rock samples,it is inferred that there is no genetic relationship between Japan arc system and KPR. It is noted that rocks reflecting continental crust basement feature have been collected on the northern tip of KPR,which may be related to the process of KPR accreting on Japan arc,but the arc-continent accretion process are still at initial stage of modern continental crust accretion model. However,due to the scarcity of data of the northern tip of KPR,crustal structure of this location and its adjacent Nankai trough need to be further constrained by geophysical studies in the future.
基金973 Jointly funded by Cenozoic Sequence Stratigraphy and Sedimentary Evolution of Continental Margin of the East China Sea under contract No.2007CB41170301Research on Sedimentary Features and Sedimentary Filling of the Lower Slope Basin in the Deep Water Area of the Middle and Northern South China Sea of the Special Fund Program of Basic Scientific Research Expenses under contract No.JG1007Supporting Technologies for Delimitation of Continental Shelves and Exclusive Economic Zones under contract Nos 200805078,201205037 and 201205003
文摘The Philippine Basin,surrounded by a series of oceanic trenches,is an independent deep ocean basin in the West Pacific Ocean.Its middle part is divided into three marginal sea sub-basins by the Kyushu-Palau and West Mariana Ridges,namely,the West Philippine Basin,the Shikoku and Parece Vela Basins and the Mariana Trough.This paper,through the analysis of the geomorphologic features and gravity and magnetic characteristics of the basin and identification of striped magnetic anomalies,suggests that the entire Philippine Basin developed magnetic lineation of oceanic nature,and therefore,the entire basin is of the nature of oceanic crust.The basin has developed a series of special geomorphic units with different shapes.The KPR runs through the entire Philippine Basin.From the view of geomorphologic features,the KPR is a discontinuous seamount chain （chain-shaped seamounts） and subduction beneath the Japanese Island arc at the Nankai Trough which is the natural boundary between the basin and the Japanese Island arc.At the positions of 25 N,24 N,23 N and 18 N,obvious discontinuity is shown,which belongs to natural topographic discontinuity.Therefore,the KPR is topographically discontinuous.
基金sponsored by the Natural Science Foundation of China(41274098)the specific program of basic science research of Institute of Earthquake Science,CEA(2013 IES0407)the subject of old expert research foundation of CEA
文摘The time series of coordinates of a large number of GPS stations in the world,processed by Prof. Geoffrey Blewitt with GIPSY software are available at http://geodesy. unr. edu.Based on the time series of coordinates in the global reference frame of IGS08 at more than250 stations of continuous GPS observations,downloaded from the website,the co-seismic displacements of the M7. 3 Kyushu earthquake on April 16,2016 in Japan and the preseismic strain accumulations and displacements in the regional reference frame were obtained. The station of continuous GPS observation at BJFS near Beijing has been quite stable in displacement in the eastern part of China for more than 17 years since the beginning of its operation,and this station is used as the core station in the regional reference frame for the pre-seismic displacement of the Kyushu earthquake of M7. 3. The main feature of the pre-seismic displacements of the Kyushu earthquake is characterized by locking in the crust at and near the epicenter. The anomalous pre-seismic strain accumulation developed in an area of anomalous accumulation of the shear strain component of γ1 on the northeast side of the epicenter,with increasing size of the area and increasing magnitude in γ1. The largest area covered by the anomalous γ1 is about 2000 km2. The change in the E component at BJFS since November 26,2015 was caused by the replacement of the receiver and the antenna at the station. In order to study the shortterm change in displacements at stations at and near the epicenter,the time series at 3 stations with continuous GPS observations,2 at SUWN and DAEJ in south Korea and 1 at BJSH near Beijing were analyzed. The analysis shows that the displacements at the 3 stations have been quite stable in the same manner in east Asia. Thus,BJSH is used as the core station in the regional reference frame of displacement and the displacement time series show that there were no significant short term anomalies before the earthquake.
文摘In this paper, the Global Satellite Mapping of Precipitation Moving Vector with Kalman filter (GSMaP_MVK) was evaluated and corrected at daily time scales with a spatial resolution of 0.1°;latitude/longitude. The reference data came from thirty-four rain gauges on Kyushu Island, Japan. This study focused on the GSMaP_MVK’s ability to detect heavy rainfall patterns that may lead to flooding. Statistical analysis was used to evaluate the GSMaP_MVK data both quantitatively and qualitatively. The statistical analysis included the relative bias (B), the mean error (E), the Nash-Sutcliffe coefficient (CNS), the Root Mean Square Error (RMSE) and the correlation coefficient (r). In addition, Generalized Additive Models (GAMs) were used to conduct GSMaP_MVK data correction. The results of these analyses indicate that GSMaP_MVK data have lower values than observed data and may be significantly underestimated during heavy rainfall. By applying GAM to bias correction, GSMaP_MVK’s ability to detect heavy rainfall was improved. In addition, GAM for bias correction could effectively be applied for significant underestimates of GSMaP_ MVK (i.e., bias of more than 55%). GAM is a new approach to predict rainfall amount for flood and landslide monitoring of satellite base precipitation, especially in areas where rain gauge data are limited.
基金Joint Seismological Sceince Foundation of China(305007).
文摘The 1975 Haicheng Ms7.3 earthquake affected whole Korean Peninsula and even Kyushu, Japan. In this paper isoseismal map of this earthquake was drawn for these areas by sorting out and analyzing data systematically collected, furthermore, the characteristics of the earthquake damage were discussed. In the northern Korean Peninsula, the intensity is V in great majority of this area except local area with intensity VI, and the damage is basically in accordance with typical characteristics of corresponding intensity grade. In the southern Korean Peninsula, the intensity is IV in large part of the area, however, in some big cities such as Seoul etc., not only high buildings shook strongly, but also some people appeared perceptions such as feeling dizzy and so on, and electrical service was interrupted on one or two districts because of transformer tripping. These phenomena could be caused by the effect of long-period wave generated from a large earthquake on far-field.
文摘The 4th International Symposium on‘Gondwana to Asia’was held in Fukuoka,Japan from 8 to 10 November,2007.After the symposium,a field excursion was held in the Kyushu Island,which started from Fukuoka city(Figure 1)on the 11 November 2007 and lasted three days until the 13th.The excursion was led by M.Owada,A.Kamei,K.Watanabe and Y.Osanai.Twenty-one geologists from fifteen countries,including Australia,Brazil,France,Germany,India,Italy,Japan,Russia,Sri Lanka,South Africa,South Korea,Thailand,UK.,USA.and Vietnam participated,making a longitudinal traverse covering most part of Kyushu(Figure 1),and enabling the participants to observe pre-Tertiary basement terranes of the Japanese islands which are interpreted in the global tectonic framework of eastern Asiatic continent and Gondwanaland,and the Pleistocene Aso volcanoes and gold mineralization of the Hishikari Gold Mine(Figure 1).On the first day,the participants stayed in the Jigoku Onsen(spa)of the Aso area and on the second day at Yuno-Onsen(spa)in the Hishikari area.About ten localities(Figure 1)were visited during the excursion.
