The technique of data mining was provided to predict gas disaster in view of the characteristics of coal mine gas disaster and feature knowledge based on gas disaster. The rough set theory was used to establish data m...The technique of data mining was provided to predict gas disaster in view of the characteristics of coal mine gas disaster and feature knowledge based on gas disaster. The rough set theory was used to establish data mining model of gas disaster prediction, and rough set attributes relations was discussed in prediction model of gas disaster to supplement the shortages of rough intensive reduction method by using information en- tropy criteria.The effectiveness and practicality of data mining technology in the prediction of gas disaster is confirmed through practical application.展开更多
Data mining is the powerful technique, which can be widely used for discovering the customers’ behaviors as well as customer’s preferences. As a result, it has been widely used in top level companies for evaluating ...Data mining is the powerful technique, which can be widely used for discovering the customers’ behaviors as well as customer’s preferences. As a result, it has been widely used in top level companies for evaluating their Customer Relationship Management (CRM) system today. In this study, a new K-means clustering method proposed to evaluate the cluster customers’ profitability in telecommunication industry in Sri Lanka. Furthermore, RFM model mainly used as an input variable for K-means clustering and distortion curve used to identify optimal number of initial clusters. Based on the results, telecommunication customers’ profitability in Sri Lanka mainly categorized into three levels.展开更多
In recent years,the rapid development of big data technology has also been favored by more and more scholars.Massive data storage and calculation problems have also been solved.At the same time,outlier detection probl...In recent years,the rapid development of big data technology has also been favored by more and more scholars.Massive data storage and calculation problems have also been solved.At the same time,outlier detection problems in mass data have also come along with it.Therefore,more research work has been devoted to the problem of outlier detection in big data.However,the existing available methods have high computation time,the improved algorithm of outlier detection is presented,which has higher performance to detect outlier.In this paper,an improved algorithm is proposed.The SMK-means is a fusion algorithm which is achieved by Mini Batch K-means based on simulated annealing algorithm for anomalous detection of massive household electricity data,which can give the number of clusters and reduce the number of iterations and improve the accuracy of clustering.In this paper,several experiments are performed to compare and analyze multiple performances of the algorithm.Through analysis,we know that the proposed algorithm is superior to the existing algorithms.展开更多
With the increasing variety of application software of meteorological satellite ground system, how to provide reasonable hardware resources and improve the efficiency of software is paid more and more attention. In th...With the increasing variety of application software of meteorological satellite ground system, how to provide reasonable hardware resources and improve the efficiency of software is paid more and more attention. In this paper, a set of software classification method based on software operating characteristics is proposed. The method uses software run-time resource consumption to describe the software running characteristics. Firstly, principal component analysis (PCA) is used to reduce the dimension of software running feature data and to interpret software characteristic information. Then the modified K-means algorithm was used to classify the meteorological data processing software. Finally, it combined with the results of principal component analysis to explain the significance of various types of integrated software operating characteristics. And it is used as the basis for optimizing the allocation of software hardware resources and improving the efficiency of software operation.展开更多
With the gradual acceleration of information construction in colleges and universities,digital campus and smart campus have gradually become important means for colleges and universities to scientifically manage the c...With the gradual acceleration of information construction in colleges and universities,digital campus and smart campus have gradually become important means for colleges and universities to scientifically manage the campus.They have been applied to teaching,scientific research,student management,and other fields,improving the quality and efficiency of management.This paper mainly studies the intelligent educational administration management system based on data mining technology.Firstly,this paper introduces the application process of data mining technology,and builds an intelligent educational administration management system based on data mining technology.Then,this paper optimizes the application of the Apriori algorithm in educational administration management through transaction compression and frequent sampling.Compared with the traditional Apriori algorithm,the optimized Apriori algorithm in this paper has a shorter execution time under the same minimum support.展开更多
In the present study,data mining and network pharmacology were utilized to explore the principles and mechanisms of traditional Chinese medicine(TCM)in treating acute appendicitis.The goal was to provide a scientific ...In the present study,data mining and network pharmacology were utilized to explore the principles and mechanisms of traditional Chinese medicine(TCM)in treating acute appendicitis.The goal was to provide a scientific basis for clinical treatment and further research on this disease.First,we searched the National Patent Database for Chinese herbal compound prescriptions used to treat acute appendicitis.We then applied frequency analysis,character and taste meridian analysis,association rule analysis,and hierarchical cluster analysis to identify the patterns of TCM treatment for acute appendicitis,selecting key combinations of Chinese medicines.Next,we screened the main active components of these key TCM based on quality markers.Using databases such as SwissTargetPrediction,SymMap,ETCM,and STRING,we analyzed the pharmacological mechanisms of these key TCM in treating acute appendicitis.Key active components and targets were further verified through molecular docking.We identified a total of 129 patents involving 316 Chinese medicines,with 24 being frequently used.The results indicated that most Chinese herbs used for acute appendicitis were heat-clearing drugs,blood-activating and stasis-removing drugs,and purging drugs.The primary active ingredients of the Rhubarb-cortex moutan-flos lonicerae combination for treating acute appendicitis included Emodin,Paeonol,Physcion,Chlorogenic acid,Chrysophanol,Rhein acid,and Aloe-emodin.These ingredients targeted key proteins such as ALB,TP53,BCL2,STAT3,IL-6,and TNF,and were involved in cellular responses to lipopolysaccharides,cell composition,and various cytokine-mediated biological processes.They also interacted with signaling pathways like AGE-RAGE,TNF,IL-17,and FoxO.Based on patent data,this study analyzed medication patterns in the treatment of acute appendicitis,discussed the possible mechanisms of key TCM combinations,and provided a scientific basis and new perspectives for the diagnosis and treatment of the disease.展开更多
Objective To identify core acupoint patterns and elucidate the molecular mechanisms of acupuncture for primary depressive disorder(PDD)through data mining and network analysis.Methods A comprehensive literature search...Objective To identify core acupoint patterns and elucidate the molecular mechanisms of acupuncture for primary depressive disorder(PDD)through data mining and network analysis.Methods A comprehensive literature search was conducted across PubMed,Embase,Ovid Technologies(OVID),Web of Science,Cochrane Library,China National Knowledge Infrastructure(CNKI),China National Knowledge Infrastructure Database(VIP),Wanfang Data,and SinoMed Database from database foundation to January 31,2025,for clinical studies on acupuncture treatment of PDD.Descriptive statistics,high-frequency acupoint analysis,degree and betweenness centrality evaluation,and core acupoint prescription mining identified predominant therapeutic combinations for PDD.Network acupuncture was used to predict therapeutic target for the core acupoint prescription.Subsequent protein-protein interaction(PPI)network and molecular complex detection(MCODE)analyses were conducted to identify the key targets and functional modules.Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analyses explored the underlying biological mechanisms of the core acupoint prescription in treating PDD.Results A total of 57 acupoint prescriptions underwent systematic analysis.The core therapeutic combinations comprised Baihui(GV20),Yintang(GV29),Neiguan(PC6),Hegu(LI4),and Shenmen(HT7).Network acupuncture analysis identified 88 potential therapeutic targets(79 overlapping with PDD),while PPI network analysis revealed central regulatory nodes,including interleukin(IL)-6,IL-1β,tumor necrosis factor(TNF)-α,toll-like receptor 4(TLR4),IL-10,brain-derived neurotrophic factor(BDNF),transforming growth factor(TGF)-β1,C-XC motif chemokine ligand 10(CXCL10),mitogen-activated protein kinase 3(MAPK3),and nitric oxide synthase 1(NOS1).MCODE-based modular analysis further elucidated three functionally coherent clusters:inflammation-homeostasis(score=6.571),plasticity-neurotransmission(score=3.143),and oxidative stress(score=3.000).GO and KEGG analyses demonstrated significant enrichment of the MAPK,phosphoinositide 3-kinase/protein kinase B(PI3K/Akt),and hypoxia-inducible factor(HIF)-1 signaling pathways.These mechanistic insights suggested that the antidepressant effects mediated through mechanisms of neuroinflammatory regulation,neuroplasticity restoration,and immune-oxidative stress homeostasis.Conclusion This study reveals that acupuncture alleviates depression through a multi-level mechanism,primarily involving the neuroinflammation suppression,neuroplasticity enhancement,and oxidative stress regulation.These findings systematically clarify the underlying mechanisms of acupuncture’s antidepressant effects and identify novel therapeutic targets for further mechanistic research.展开更多
Objective To explore the optimization and principles of acupoint selection and coordination in the treatment of adult abdominal obesity using acupuncture and moxibustion over the past decade using data mining.Methods ...Objective To explore the optimization and principles of acupoint selection and coordination in the treatment of adult abdominal obesity using acupuncture and moxibustion over the past decade using data mining.Methods Clinical studies of abdominal obesity treated with acupuncture and moxibustion,collected in the past 10 years,were searched from China Biology Medicine disc(CBMdisc),China National knowledge infrastructure(CNKI),Wanfang,China Science and Technology Journal Database(VIP),Pubmed,Embase,Google Scholar,Web of Science,(The Cumulative Index to Nursing and Allied Health Literature)CINAHL,Psyclnfo and Scopus,dated from March 1,2013 to March 31,2023.Using IBM SPSS Modeler 18.0 and other software,the frequency analysis,association-rules analysis and cluster analysis were conducted on interventions,traditional Chinese medicine(TCM)patterns,use frequency of acupoint,meridian attribution of acupoint,acupoint location,etc.Results A total of 55 articles were included,with 102 prescriptions and 71 acupoints involved.The top 3 interventions were acupoint embedding method,simple electroacupuncture and simple filiform needling.Seventeen patterns/syndromes of TCM differentiation were collected,dominated by spleen deficiency and damp blockage,spleen and kidney yang deficiency and heat accumulation in stomach and intestines.The acupoints in clinical practice were mostly at the foot-yangming stomach meridian,the conception vessel and the foot-taiyin spleen meridian,and located at the abdominal region.The top 5 acupoints of high frequency were Tianshu(ST25),Zhongwan(CV12),Daheng(SP15),Zusanli(ST36),Huaroumen(ST24)and Daimai(GB26).The specific points of the high frequency were the crossing points and front-mu points,of which,ST25 and CV12 were the most prominent.After association-rules analysis on the high-frequency acupoints,20 groups of associated acupoints were obtained,in which,the core acupoints included ST25,CV12,SP15 and ST36.Conclusion In recent 10 years,abdominal obesity is treated by the acupoints of foot-yangming stomach meridian,the conception vessel and the foot-taiyin spleen meridian.Compared with the regimen for simple obesity,the acupoints at the abdominal region are specially selected in treatment of abdominal obesity,such as ST25,CV12,SP15 and ST36.Supplementary acupoints are selected based on syndrome differentiation to simultaneously address both the disease manifestations and root causes.展开更多
Objective:To explore the core acupuncture acupoints and pattern-adapted acupoint combination rules for autism spectrum disorder(ASD)complicated with sleep disorder using clinical data mining technology.Methods:A retro...Objective:To explore the core acupuncture acupoints and pattern-adapted acupoint combination rules for autism spectrum disorder(ASD)complicated with sleep disorder using clinical data mining technology.Methods:A retrospective analysis was conducted on the diagnosis and treatment data of 104 children with ASD complicated with sleep disorder admitted to Xi’an Traditional Chinese Medicine(TCM)Encephalopathy Hospital from January 2022 to December 2024.Cross-pattern main acupoints were screened via frequency statistics,chi-square test,and factor analysis;pattern-specific auxiliary acupoints were extracted by combining multiple correspondence analysis,cluster analysis,and association rule mining.Results:Ten cross-pattern main acupoints(Baihui,Sishenzhen,Language Area 1,Language Area 2,Neiguan,Shenmen,Yongquan,Xuanzhong)were identified,and acupoint combination schemes for four major TCM patterns(Hyperactivity of Liver and Heart Fire,Deficiency of Kidney Essence,Deficiency of Both Heart and Spleen,Hyperactivity of Liver with Spleen Deficiency)were established.Conclusion:Acupuncture treatment should follow the principle of“regulating spirit and calming the brain as the root,and dredging collaterals based on pattern differentiation as the branch”.The synergy between main and auxiliary acupoints can accurately regulate the disease,providing a basis for precise clinical treatment.展开更多
A deep-sea riser is a crucial component of the mining system used to lift seafloor mineral resources to the vessel.Even minor damage to the riser can lead to substantial financial losses,environmental impacts,and safe...A deep-sea riser is a crucial component of the mining system used to lift seafloor mineral resources to the vessel.Even minor damage to the riser can lead to substantial financial losses,environmental impacts,and safety hazards.However,identifying modal parameters for structural health monitoring remains a major challenge due to its large deformations and flexibility.Vibration signal-based methods are essential for detecting damage and enabling timely maintenance to minimize losses.However,accurately extracting features from one-dimensional(1D)signals is often hindered by various environmental factors and measurement noises.To address this challenge,a novel approach based on a residual convolutional auto-encoder(RCAE)is proposed for detecting damage in deep-sea mining risers,incorporating a data fusion strategy.First,principal component analysis(PCA)is applied to reduce environmental fluctuations and fuse multisensor strain readings.Subsequently,a 1D-RCAE is used to extract damage-sensitive features(DSFs)from the fused dataset.A Mahalanobis distance indicator is established to compare the DSFs of the testing and healthy risers.The specific threshold for these distances is determined using the 3σcriterion,which is employed to assess whether damage has occurred in the testing riser.The effectiveness and robustness of the proposed approach are verified through numerical simulations of a 500-m riser and experimental tests on a 6-m riser.Moreover,the impact of contaminated noise and environmental fluctuations is examined.Results show that the proposed PCA-1D-RCAE approach can effectively detect damage and is resilient to measurement noise and environmental fluctuations.The accuracy exceeds 98%under noise-free conditions and remains above 90%even with 10 dB noise.This novel approach has the potential to establish a new standard for evaluating the health and integrity of risers during mining operations,thereby reducing the high costs and risks associated with failures.Maintenance activities can be scheduled more efficiently by enabling early and accurate detection of riser damage,minimizing downtime and avoiding catastrophic failures.展开更多
Introduction Neurosurgical emergencies such as spontaneous intracerebral hemorrhage(ICH),traumatic brain injury(TBI),and acute brain herniation are among the most time-sensitive and high-stakes conditions in modern me...Introduction Neurosurgical emergencies such as spontaneous intracerebral hemorrhage(ICH),traumatic brain injury(TBI),and acute brain herniation are among the most time-sensitive and high-stakes conditions in modern medicine.Clinical decisions often must be made within minutes,yet these decisions are traditionally guided by limited information,heuristic reasoning,and past experience.In this context,the rise of medical data mining and real-time analytics offers a transformative opportunity:to extract actionable intelligence from the flood of clinical,imaging,and physiological data already being collected,and to use this intelligence to guide care in real time[1–3](Figure 1).展开更多
Previous weighted frequent pattern （WFP） mining algorithms are not suitable for data streams for they need multiple database scans. In this paper, we present an efficient algorithm SWFP-Miner to mine weighted freque...Previous weighted frequent pattern （WFP） mining algorithms are not suitable for data streams for they need multiple database scans. In this paper, we present an efficient algorithm SWFP-Miner to mine weighted frequent pattern over data streams. SWFP-Miner is based on sliding window and can discover important frequent pattern from the recent data. A new refined weight definition is proposed to keep the downward closure property, and two pruning strategies are presented to prune the weighted infrequent pattern. Experimental studies are performed to evaluate the effectiveness and efficiency of SWFP-Miner.展开更多
Cluster analysis is one of the major data analysis methods widely used for many practical applications in emerging areas of data mining. A good clustering method will produce high quality clusters with high intra-clus...Cluster analysis is one of the major data analysis methods widely used for many practical applications in emerging areas of data mining. A good clustering method will produce high quality clusters with high intra-cluster similarity and low inter-cluster similarity. Clustering techniques are applied in different domains to predict future trends of available data and its uses for the real world. This research work is carried out to find the performance of two of the most delegated, partition based clustering algorithms namely k-Means and k-Medoids. A state of art analysis of these two algorithms is implemented and performance is analyzed based on their clustering result quality by means of its execution time and other components. Telecommunication data is the source data for this analysis. The connection oriented broadband data is given as input to find the clustering quality of the algorithms. Distance between the server locations and their connection is considered for clustering. Execution time for each algorithm is analyzed and the results are compared with one another. Results found in comparison study are satisfactory for the chosen application.展开更多
With the advent of the era of big data and the development and construction of smart campuses,the campus is gradually moving towards digitalization,networking and informationization.The campus card is an important par...With the advent of the era of big data and the development and construction of smart campuses,the campus is gradually moving towards digitalization,networking and informationization.The campus card is an important part of the construction of a smart campus,and the massive data it generates can indirectly reflect the living conditions of students at school.In the face of the campus card,how to quickly and accurately obtain the information required by users from the massive data sets has become an urgent problem that needs to be solved.This paper proposes a data mining algorithm based on K-Means clustering and time series.It analyzes the consumption data of a college student’s card to deeply mine and analyze the daily life consumer behavior habits of students,and to make an accurate judgment on the specific life consumer behavior.The algorithm proposed in this paper provides a practical reference for the construction of smart campuses in universities,and has important theoretical and application values.展开更多
The critical nature of satellite network traffic provides a challenging environment to detect intrusions. The intrusion detection method presented aims to raise an alert whenever satellite network signals begin to exh...The critical nature of satellite network traffic provides a challenging environment to detect intrusions. The intrusion detection method presented aims to raise an alert whenever satellite network signals begin to exhibit anomalous patterns determined by Euclidian distance metric. In line with anomaly-based intrusion detection systems, the method presented relies heavily on building a model of＂normal＂ through the creation of a signal dictionary using windowing and k-means clustering. The results of three signals fi＇om our case study are discussed to highlight the benefits and drawbacks of the method presented. Our preliminary results demonstrate that the clustering technique used has great potential for intrusion detection for non-periodic satellite network signals.展开更多
基金the National Natural Science Foundation of China(70572070)the Liaoning Province Talents Fund Projects(2005219005)the Technology Key Project of Liaoning Province(2006220019)
文摘The technique of data mining was provided to predict gas disaster in view of the characteristics of coal mine gas disaster and feature knowledge based on gas disaster. The rough set theory was used to establish data mining model of gas disaster prediction, and rough set attributes relations was discussed in prediction model of gas disaster to supplement the shortages of rough intensive reduction method by using information en- tropy criteria.The effectiveness and practicality of data mining technology in the prediction of gas disaster is confirmed through practical application.
文摘Data mining is the powerful technique, which can be widely used for discovering the customers’ behaviors as well as customer’s preferences. As a result, it has been widely used in top level companies for evaluating their Customer Relationship Management (CRM) system today. In this study, a new K-means clustering method proposed to evaluate the cluster customers’ profitability in telecommunication industry in Sri Lanka. Furthermore, RFM model mainly used as an input variable for K-means clustering and distortion curve used to identify optimal number of initial clusters. Based on the results, telecommunication customers’ profitability in Sri Lanka mainly categorized into three levels.
文摘In recent years,the rapid development of big data technology has also been favored by more and more scholars.Massive data storage and calculation problems have also been solved.At the same time,outlier detection problems in mass data have also come along with it.Therefore,more research work has been devoted to the problem of outlier detection in big data.However,the existing available methods have high computation time,the improved algorithm of outlier detection is presented,which has higher performance to detect outlier.In this paper,an improved algorithm is proposed.The SMK-means is a fusion algorithm which is achieved by Mini Batch K-means based on simulated annealing algorithm for anomalous detection of massive household electricity data,which can give the number of clusters and reduce the number of iterations and improve the accuracy of clustering.In this paper,several experiments are performed to compare and analyze multiple performances of the algorithm.Through analysis,we know that the proposed algorithm is superior to the existing algorithms.
文摘With the increasing variety of application software of meteorological satellite ground system, how to provide reasonable hardware resources and improve the efficiency of software is paid more and more attention. In this paper, a set of software classification method based on software operating characteristics is proposed. The method uses software run-time resource consumption to describe the software running characteristics. Firstly, principal component analysis (PCA) is used to reduce the dimension of software running feature data and to interpret software characteristic information. Then the modified K-means algorithm was used to classify the meteorological data processing software. Finally, it combined with the results of principal component analysis to explain the significance of various types of integrated software operating characteristics. And it is used as the basis for optimizing the allocation of software hardware resources and improving the efficiency of software operation.
文摘With the gradual acceleration of information construction in colleges and universities,digital campus and smart campus have gradually become important means for colleges and universities to scientifically manage the campus.They have been applied to teaching,scientific research,student management,and other fields,improving the quality and efficiency of management.This paper mainly studies the intelligent educational administration management system based on data mining technology.Firstly,this paper introduces the application process of data mining technology,and builds an intelligent educational administration management system based on data mining technology.Then,this paper optimizes the application of the Apriori algorithm in educational administration management through transaction compression and frequent sampling.Compared with the traditional Apriori algorithm,the optimized Apriori algorithm in this paper has a shorter execution time under the same minimum support.
基金Henan Province Special Research Project of Tra ditional Chinese Medicine(Grant No.2022ZY1090).
文摘In the present study,data mining and network pharmacology were utilized to explore the principles and mechanisms of traditional Chinese medicine(TCM)in treating acute appendicitis.The goal was to provide a scientific basis for clinical treatment and further research on this disease.First,we searched the National Patent Database for Chinese herbal compound prescriptions used to treat acute appendicitis.We then applied frequency analysis,character and taste meridian analysis,association rule analysis,and hierarchical cluster analysis to identify the patterns of TCM treatment for acute appendicitis,selecting key combinations of Chinese medicines.Next,we screened the main active components of these key TCM based on quality markers.Using databases such as SwissTargetPrediction,SymMap,ETCM,and STRING,we analyzed the pharmacological mechanisms of these key TCM in treating acute appendicitis.Key active components and targets were further verified through molecular docking.We identified a total of 129 patents involving 316 Chinese medicines,with 24 being frequently used.The results indicated that most Chinese herbs used for acute appendicitis were heat-clearing drugs,blood-activating and stasis-removing drugs,and purging drugs.The primary active ingredients of the Rhubarb-cortex moutan-flos lonicerae combination for treating acute appendicitis included Emodin,Paeonol,Physcion,Chlorogenic acid,Chrysophanol,Rhein acid,and Aloe-emodin.These ingredients targeted key proteins such as ALB,TP53,BCL2,STAT3,IL-6,and TNF,and were involved in cellular responses to lipopolysaccharides,cell composition,and various cytokine-mediated biological processes.They also interacted with signaling pathways like AGE-RAGE,TNF,IL-17,and FoxO.Based on patent data,this study analyzed medication patterns in the treatment of acute appendicitis,discussed the possible mechanisms of key TCM combinations,and provided a scientific basis and new perspectives for the diagnosis and treatment of the disease.
文摘Objective To identify core acupoint patterns and elucidate the molecular mechanisms of acupuncture for primary depressive disorder(PDD)through data mining and network analysis.Methods A comprehensive literature search was conducted across PubMed,Embase,Ovid Technologies(OVID),Web of Science,Cochrane Library,China National Knowledge Infrastructure(CNKI),China National Knowledge Infrastructure Database(VIP),Wanfang Data,and SinoMed Database from database foundation to January 31,2025,for clinical studies on acupuncture treatment of PDD.Descriptive statistics,high-frequency acupoint analysis,degree and betweenness centrality evaluation,and core acupoint prescription mining identified predominant therapeutic combinations for PDD.Network acupuncture was used to predict therapeutic target for the core acupoint prescription.Subsequent protein-protein interaction(PPI)network and molecular complex detection(MCODE)analyses were conducted to identify the key targets and functional modules.Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analyses explored the underlying biological mechanisms of the core acupoint prescription in treating PDD.Results A total of 57 acupoint prescriptions underwent systematic analysis.The core therapeutic combinations comprised Baihui(GV20),Yintang(GV29),Neiguan(PC6),Hegu(LI4),and Shenmen(HT7).Network acupuncture analysis identified 88 potential therapeutic targets(79 overlapping with PDD),while PPI network analysis revealed central regulatory nodes,including interleukin(IL)-6,IL-1β,tumor necrosis factor(TNF)-α,toll-like receptor 4(TLR4),IL-10,brain-derived neurotrophic factor(BDNF),transforming growth factor(TGF)-β1,C-XC motif chemokine ligand 10(CXCL10),mitogen-activated protein kinase 3(MAPK3),and nitric oxide synthase 1(NOS1).MCODE-based modular analysis further elucidated three functionally coherent clusters:inflammation-homeostasis(score=6.571),plasticity-neurotransmission(score=3.143),and oxidative stress(score=3.000).GO and KEGG analyses demonstrated significant enrichment of the MAPK,phosphoinositide 3-kinase/protein kinase B(PI3K/Akt),and hypoxia-inducible factor(HIF)-1 signaling pathways.These mechanistic insights suggested that the antidepressant effects mediated through mechanisms of neuroinflammatory regulation,neuroplasticity restoration,and immune-oxidative stress homeostasis.Conclusion This study reveals that acupuncture alleviates depression through a multi-level mechanism,primarily involving the neuroinflammation suppression,neuroplasticity enhancement,and oxidative stress regulation.These findings systematically clarify the underlying mechanisms of acupuncture’s antidepressant effects and identify novel therapeutic targets for further mechanistic research.
基金Supported by Shanghai College Students Innovation and Entrepreneurship Training Program Project:202310268066The 16th Batch of Science And Technology Innovation Projects of Shanghai University of Traditional Chinese Medicine:SHUTCM2023010+1 种基金2024 Shanghai Oriental Talent Program Youth Project2021 High-level Local University Innovation Team Project of Shanghai University of Traditional Chinese Medicine:No.3 Shanghai Education Commission Personnel [2022]。
文摘Objective To explore the optimization and principles of acupoint selection and coordination in the treatment of adult abdominal obesity using acupuncture and moxibustion over the past decade using data mining.Methods Clinical studies of abdominal obesity treated with acupuncture and moxibustion,collected in the past 10 years,were searched from China Biology Medicine disc(CBMdisc),China National knowledge infrastructure(CNKI),Wanfang,China Science and Technology Journal Database(VIP),Pubmed,Embase,Google Scholar,Web of Science,(The Cumulative Index to Nursing and Allied Health Literature)CINAHL,Psyclnfo and Scopus,dated from March 1,2013 to March 31,2023.Using IBM SPSS Modeler 18.0 and other software,the frequency analysis,association-rules analysis and cluster analysis were conducted on interventions,traditional Chinese medicine(TCM)patterns,use frequency of acupoint,meridian attribution of acupoint,acupoint location,etc.Results A total of 55 articles were included,with 102 prescriptions and 71 acupoints involved.The top 3 interventions were acupoint embedding method,simple electroacupuncture and simple filiform needling.Seventeen patterns/syndromes of TCM differentiation were collected,dominated by spleen deficiency and damp blockage,spleen and kidney yang deficiency and heat accumulation in stomach and intestines.The acupoints in clinical practice were mostly at the foot-yangming stomach meridian,the conception vessel and the foot-taiyin spleen meridian,and located at the abdominal region.The top 5 acupoints of high frequency were Tianshu(ST25),Zhongwan(CV12),Daheng(SP15),Zusanli(ST36),Huaroumen(ST24)and Daimai(GB26).The specific points of the high frequency were the crossing points and front-mu points,of which,ST25 and CV12 were the most prominent.After association-rules analysis on the high-frequency acupoints,20 groups of associated acupoints were obtained,in which,the core acupoints included ST25,CV12,SP15 and ST36.Conclusion In recent 10 years,abdominal obesity is treated by the acupoints of foot-yangming stomach meridian,the conception vessel and the foot-taiyin spleen meridian.Compared with the regimen for simple obesity,the acupoints at the abdominal region are specially selected in treatment of abdominal obesity,such as ST25,CV12,SP15 and ST36.Supplementary acupoints are selected based on syndrome differentiation to simultaneously address both the disease manifestations and root causes.
基金Song Hujie’s Inheritance Studio of National Renowned Traditional Chinese Medicine Experts.
文摘Objective:To explore the core acupuncture acupoints and pattern-adapted acupoint combination rules for autism spectrum disorder(ASD)complicated with sleep disorder using clinical data mining technology.Methods:A retrospective analysis was conducted on the diagnosis and treatment data of 104 children with ASD complicated with sleep disorder admitted to Xi’an Traditional Chinese Medicine(TCM)Encephalopathy Hospital from January 2022 to December 2024.Cross-pattern main acupoints were screened via frequency statistics,chi-square test,and factor analysis;pattern-specific auxiliary acupoints were extracted by combining multiple correspondence analysis,cluster analysis,and association rule mining.Results:Ten cross-pattern main acupoints(Baihui,Sishenzhen,Language Area 1,Language Area 2,Neiguan,Shenmen,Yongquan,Xuanzhong)were identified,and acupoint combination schemes for four major TCM patterns(Hyperactivity of Liver and Heart Fire,Deficiency of Kidney Essence,Deficiency of Both Heart and Spleen,Hyperactivity of Liver with Spleen Deficiency)were established.Conclusion:Acupuncture treatment should follow the principle of“regulating spirit and calming the brain as the root,and dredging collaterals based on pattern differentiation as the branch”.The synergy between main and auxiliary acupoints can accurately regulate the disease,providing a basis for precise clinical treatment.
基金the National Key Research and Development Program of China(No.2023 YFC2811600)the National Natural Science Foundation of China(Nos.52301349,52088102)+1 种基金the Major Science and Technology Innovation Program of Qingdao(No.223-3-hygg-10-hy)the Qingdao Science Foundation for Post-doctoral Scientists(Nos.QDBSH20220202070,QDBSH20220201015)。
文摘A deep-sea riser is a crucial component of the mining system used to lift seafloor mineral resources to the vessel.Even minor damage to the riser can lead to substantial financial losses,environmental impacts,and safety hazards.However,identifying modal parameters for structural health monitoring remains a major challenge due to its large deformations and flexibility.Vibration signal-based methods are essential for detecting damage and enabling timely maintenance to minimize losses.However,accurately extracting features from one-dimensional(1D)signals is often hindered by various environmental factors and measurement noises.To address this challenge,a novel approach based on a residual convolutional auto-encoder(RCAE)is proposed for detecting damage in deep-sea mining risers,incorporating a data fusion strategy.First,principal component analysis(PCA)is applied to reduce environmental fluctuations and fuse multisensor strain readings.Subsequently,a 1D-RCAE is used to extract damage-sensitive features(DSFs)from the fused dataset.A Mahalanobis distance indicator is established to compare the DSFs of the testing and healthy risers.The specific threshold for these distances is determined using the 3σcriterion,which is employed to assess whether damage has occurred in the testing riser.The effectiveness and robustness of the proposed approach are verified through numerical simulations of a 500-m riser and experimental tests on a 6-m riser.Moreover,the impact of contaminated noise and environmental fluctuations is examined.Results show that the proposed PCA-1D-RCAE approach can effectively detect damage and is resilient to measurement noise and environmental fluctuations.The accuracy exceeds 98%under noise-free conditions and remains above 90%even with 10 dB noise.This novel approach has the potential to establish a new standard for evaluating the health and integrity of risers during mining operations,thereby reducing the high costs and risks associated with failures.Maintenance activities can be scheduled more efficiently by enabling early and accurate detection of riser damage,minimizing downtime and avoiding catastrophic failures.
文摘Introduction Neurosurgical emergencies such as spontaneous intracerebral hemorrhage(ICH),traumatic brain injury(TBI),and acute brain herniation are among the most time-sensitive and high-stakes conditions in modern medicine.Clinical decisions often must be made within minutes,yet these decisions are traditionally guided by limited information,heuristic reasoning,and past experience.In this context,the rise of medical data mining and real-time analytics offers a transformative opportunity:to extract actionable intelligence from the flood of clinical,imaging,and physiological data already being collected,and to use this intelligence to guide care in real time[1–3](Figure 1).
文摘Previous weighted frequent pattern （WFP） mining algorithms are not suitable for data streams for they need multiple database scans. In this paper, we present an efficient algorithm SWFP-Miner to mine weighted frequent pattern over data streams. SWFP-Miner is based on sliding window and can discover important frequent pattern from the recent data. A new refined weight definition is proposed to keep the downward closure property, and two pruning strategies are presented to prune the weighted infrequent pattern. Experimental studies are performed to evaluate the effectiveness and efficiency of SWFP-Miner.
文摘Cluster analysis is one of the major data analysis methods widely used for many practical applications in emerging areas of data mining. A good clustering method will produce high quality clusters with high intra-cluster similarity and low inter-cluster similarity. Clustering techniques are applied in different domains to predict future trends of available data and its uses for the real world. This research work is carried out to find the performance of two of the most delegated, partition based clustering algorithms namely k-Means and k-Medoids. A state of art analysis of these two algorithms is implemented and performance is analyzed based on their clustering result quality by means of its execution time and other components. Telecommunication data is the source data for this analysis. The connection oriented broadband data is given as input to find the clustering quality of the algorithms. Distance between the server locations and their connection is considered for clustering. Execution time for each algorithm is analyzed and the results are compared with one another. Results found in comparison study are satisfactory for the chosen application.
基金Science and Technology Project of Guizhou Province of China(Grant QKHJC[2019]1403)and(Grant QKHJC[2019]1041)Guizhou Province Colleges and Universities Top Technology Talent Support Program(Grant QJHKY[2016]068).
文摘With the advent of the era of big data and the development and construction of smart campuses,the campus is gradually moving towards digitalization,networking and informationization.The campus card is an important part of the construction of a smart campus,and the massive data it generates can indirectly reflect the living conditions of students at school.In the face of the campus card,how to quickly and accurately obtain the information required by users from the massive data sets has become an urgent problem that needs to be solved.This paper proposes a data mining algorithm based on K-Means clustering and time series.It analyzes the consumption data of a college student’s card to deeply mine and analyze the daily life consumer behavior habits of students,and to make an accurate judgment on the specific life consumer behavior.The algorithm proposed in this paper provides a practical reference for the construction of smart campuses in universities,and has important theoretical and application values.
文摘The critical nature of satellite network traffic provides a challenging environment to detect intrusions. The intrusion detection method presented aims to raise an alert whenever satellite network signals begin to exhibit anomalous patterns determined by Euclidian distance metric. In line with anomaly-based intrusion detection systems, the method presented relies heavily on building a model of＂normal＂ through the creation of a signal dictionary using windowing and k-means clustering. The results of three signals fi＇om our case study are discussed to highlight the benefits and drawbacks of the method presented. Our preliminary results demonstrate that the clustering technique used has great potential for intrusion detection for non-periodic satellite network signals.
