The development of innovative and sustainable catalytic strategies for organic synthesis is a pivotal aspect of advancing material science and chemical engineering.This research presents a new catalytic method for the...The development of innovative and sustainable catalytic strategies for organic synthesis is a pivotal aspect of advancing material science and chemical engineering.This research presents a new catalytic method for the aminoacylation of N-sulfonyl ketimines by utilizing a potassium-doped graphite-like carbon nitride(g-C_(3)N_(4))framework.This method not only enhances the catalytic efficiency and broadens the light absorption spectrum of g-C_(3)N_(4)but also significantly reduces the recombination rate of electronhole pairs,thereby increasing the reaction yield and selectivity.Importantly,our approach facilitates the synthesis of aminoacylated N-heterocycles,expanding the applicability of potassium-modified g-C_(3)N_(4)in photocatalytic organic synthesis.A notable accomplishment of this study is the unprecedented generation of carbamoyl radicals via heterogeneous photocatalysis,which can be easily recycled after reaction.This advancement highlights the capability of potassium-doped g-C_(3)N_(4)(namely K-CN)as an advanced heterogeneous photocatalyst for the formation of complex organic compounds.展开更多
目的分析副溶血弧菌O10:K4血清型O抗原基因簇的分子特征,并构建基于基因组的分子血清型预测数据库。方法从美国国家生物技术信息中心Assembly数据库获取副溶血弧菌O抗原基因簇序列,使用blastn、fastANI、Sourmash和p i x y工具分析序列...目的分析副溶血弧菌O10:K4血清型O抗原基因簇的分子特征,并构建基于基因组的分子血清型预测数据库。方法从美国国家生物技术信息中心Assembly数据库获取副溶血弧菌O抗原基因簇序列,使用blastn、fastANI、Sourmash和p i x y工具分析序列相似性和多态性,使用g u b b i n s进行重组分析,并构建了副溶血弧菌分子血清型预测数据库。结果O10:K4的O抗原基因簇(OL10V1)与传统O10血清型基因簇(OL10)序列差异显著,而与OL4最为相似。公共数据库中116个OL10V1全长序列仅存在1个单核苷酸突变。OL10V1携带的IS1634和ISVa2转座酶基因广泛分布于弧菌属,提示该变异体可能通过水平基因转移形成。结论本研究揭示了O10:K4血清型快速传播的潜在分子机制,构建的分子血清型数据库可为基因组监测和溯源提供关键技术支撑。展开更多
基金financial support from the National Natural Science Foundation of China(No.22171249)the Science&Technology Innovation Talents in Universities of Henan Province(No.23HASTIT003)。
文摘The development of innovative and sustainable catalytic strategies for organic synthesis is a pivotal aspect of advancing material science and chemical engineering.This research presents a new catalytic method for the aminoacylation of N-sulfonyl ketimines by utilizing a potassium-doped graphite-like carbon nitride(g-C_(3)N_(4))framework.This method not only enhances the catalytic efficiency and broadens the light absorption spectrum of g-C_(3)N_(4)but also significantly reduces the recombination rate of electronhole pairs,thereby increasing the reaction yield and selectivity.Importantly,our approach facilitates the synthesis of aminoacylated N-heterocycles,expanding the applicability of potassium-modified g-C_(3)N_(4)in photocatalytic organic synthesis.A notable accomplishment of this study is the unprecedented generation of carbamoyl radicals via heterogeneous photocatalysis,which can be easily recycled after reaction.This advancement highlights the capability of potassium-doped g-C_(3)N_(4)(namely K-CN)as an advanced heterogeneous photocatalyst for the formation of complex organic compounds.
文摘目的分析副溶血弧菌O10:K4血清型O抗原基因簇的分子特征,并构建基于基因组的分子血清型预测数据库。方法从美国国家生物技术信息中心Assembly数据库获取副溶血弧菌O抗原基因簇序列,使用blastn、fastANI、Sourmash和p i x y工具分析序列相似性和多态性,使用g u b b i n s进行重组分析,并构建了副溶血弧菌分子血清型预测数据库。结果O10:K4的O抗原基因簇(OL10V1)与传统O10血清型基因簇(OL10)序列差异显著,而与OL4最为相似。公共数据库中116个OL10V1全长序列仅存在1个单核苷酸突变。OL10V1携带的IS1634和ISVa2转座酶基因广泛分布于弧菌属,提示该变异体可能通过水平基因转移形成。结论本研究揭示了O10:K4血清型快速传播的潜在分子机制,构建的分子血清型数据库可为基因组监测和溯源提供关键技术支撑。
