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Effectiveness of electroacupuncture at Jiaji acupoints(EX-B 2), plus moxibustion and intermediate on postherpetic neuralgia: a randomized controlled trial 被引量:12
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作者 Wang Lei Qiu Ling +6 位作者 Zheng Xu Ou-yang Jian-bing Zhang Min He Liu Zeng Shuai Liu Bo Peng Jinlin 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2020年第1期121-127,共7页
OBJECTIVE:To investigate the effectiveness of electroacupuncture at Jiaji acupoints(EX-B 2)plus moxibustion and intermediate frequency on postherpetic neuralgia(PHN).METHODS:A total of 140 outpatients who satisfied th... OBJECTIVE:To investigate the effectiveness of electroacupuncture at Jiaji acupoints(EX-B 2)plus moxibustion and intermediate frequency on postherpetic neuralgia(PHN).METHODS:A total of 140 outpatients who satisfied the inclusion criteria and volunteered for this treatment were randomly divided into treatment(n=70)and control(n=70)groups.Both groups received a localized lesion area and electroacupuncture treatment combined with moxibustion and intermediate frequency.The treatment group(TG)increased acupuncture at Jiaji acupoints(EX-B 2)and electroacupuncture.Pain and anxiety were assessed before and after 5,10,15,and 20 treatments by using visual pain simulation score(VAS)and Hamilton anxiety scale(HAMA),respectively.Clinical efficacy was also evaluated.RESULTS:The baseline between the two groups did not significantly differ(P>0.05).The VAS and HAMA scores of the two groups after treatment significantly decreased compared with those of various treatment stages(P>0.05).The HAMA score(P<0.01)of TG was lower than that of the control group(CG).The VAS score of TG was lower than that of CG in the 5th and 10th treatments(P<0.01).In the 15 th and 10 th scores,CG was also superior to TG(P<0.05).CONCLUSION:The combined treatment of electroacupuncture at Jiaji acupoints(EX-B 2),moxibustion,and intermediate frequency can relieve the pain and anxiety symptoms of PHN.The efficacy of the combined treatment was superior to traditional acupuncture. 展开更多
关键词 ELECTROACUPUNCTURE Point EX-B 2(jiaji) Neuralgia postherpetic Pain Randomized controlled trial
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Sixty-five cases of cervical vertigo treated by needling cervical jiaji points in combination with acupoint pressing 被引量:1
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作者 李巍 谭洛 王淑琴 《World Journal of Acupuncture-Moxibustion》 2013年第2期48-50,54,共4页
Objective To observe the clinical efficacy of needling cervical Jiaji points in combination with acupoint pressing for cervical vertigo, and provide a better therapy for the clinical treatment of this disease. Methods... Objective To observe the clinical efficacy of needling cervical Jiaji points in combination with acupoint pressing for cervical vertigo, and provide a better therapy for the clinical treatment of this disease. Methods Sixty-five patients with cervical vertigo were punctured at the points Cervical jiaji and Fengchi (风池 GB 20) bilaterally, from Qiangjian (强间 GV 18) to Naohu (脑户 GV 17), from Yuzhen (玉枕 BL 9) to Tianzhu (天柱 BL 10) with penetrating methods, besides, acupoint pressing was also used on these points. It was given once a day, and 16 times constituted one course with 2 courses together, and then the clinical efficacy was observed. Results Twenty-five cases were cured accounting to 38.5%; 18 remarkably improved accounting to 27.7%; 19 improved accounting to 29.2%; 3 ineffective accounting to 4.6%. The total effective rate was 95.4%. Conclusion Needling cervical Jiaji points in combination with acupoint pressing can alleviate the clinical symptoms of cervical vertigo and worthy of being promoted. 展开更多
关键词 cervical vertigo cerical jiaji MASSAGE acupuncture therapy
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THE TREATMENT OF CERVICAL SPONDYLOPATHY BY LASER ACUPUNCTURE AT THE CERVICAL JIAJI POINTS: AN ANALYSIS OF THERAPEUTIC EFFECT OF 102 CASES
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作者 Shan Qiuhua, Qin Pengxiu, Xiao FeiAcupuncture and Moxibustion Department, The Affiliated Hospital of Shandong College of Traditional Chinese Medicine, Jinan 250011, China 《World Journal of Acupuncture-Moxibustion》 1994年第1期6-8,19,共4页
Laser acupuncture therapy was employed in the treatment of spondylopathy.Thetherapeutic effect of the three types of the spondylopathy,nerve root type,vertebral artery type andspinal cord type were stuied and compared... Laser acupuncture therapy was employed in the treatment of spondylopathy.Thetherapeutic effect of the three types of the spondylopathy,nerve root type,vertebral artery type andspinal cord type were stuied and compared.The results indicate a significant difference between thethree types of spondylopathy.The best therapeutic effect was obtained in nerve root type with a remarkable effective rate of 98.5%;the effective rates for the vertebral artery type and the spinal cordtype were 92.3%and 25%,respectively.Combining laser irradiatlon with acupuncture,the therapyposseses the functions of acupuncture,heat effect and mild moxibustion action.Therefore,it showedeffect quickly and had the advantages of short treatment course and high therapeutic effect.Clinicalobservation has confirmed that laser acupuncture is more effective than single laser irradiation.Thistherapy offers another simple but effective method for the treatment of spondylopathy. 展开更多
关键词 Osteophytosis SPONDYLOPATHY Laser ACUPUNCTURE jiaji POINTS (EX-B2)
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Effect of electroacupuncture at Jiaji (EX-B2) points on the expression of microRNA-21 and neuronal apoptosis in rats with acute spinal cord injury
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作者 Hui-Jie Chen Xiu-Ming Pang +1 位作者 Song-Yin Zheng Yan Wang 《Journal of Hainan Medical University》 2019年第22期22-26,共5页
Objective:To observe the effect of electroacupuncture at Jiaji (EX-B2) points on the expression of microRNA-21 and neuronal apoptosis in rats with acute spinal cord injury. Methods:SD rats were randomly divided into s... Objective:To observe the effect of electroacupuncture at Jiaji (EX-B2) points on the expression of microRNA-21 and neuronal apoptosis in rats with acute spinal cord injury. Methods:SD rats were randomly divided into sham-operated group, model group, electro-acupuncture group and methylprednisolone group. The model of acute spinal cord injury was reproduced by modified Allen's method. Each group was given corresponding intervention treatment 2 hours after modeling. The electroacupuncture group was treated with electro-acupuncture at Jiaji (EX-B2) points in T8 to T12, the methylprednisolone group was given intraperitoneal injection of 30 mg/kg methylprednisolone sodium succinate, and the sham operation group and model group were not treated. After treatment, BBB scores were observed to evaluate the motor function of posterior limb in each group, and the injured spinal cord tissues were taken. The pathological changes of spinal cord neuropathy were observed by Nissl staining. The expression of microRNA-21 was detected by RT-qPCR, and the expression of apoptotic proteins (Bax, Bcl-2 and cleaved-Caspase-3) was detected by Western-Blot. Result:Compared with sham operation group, BBB, neuron survival rate and expression of microRNA-21 were significantly lower, apoptotic rate of neurons was significantly higher, expression of Bax, Bcl-2, cleaved Caspase-3 protein and Bax/Bcl-2 ratio were significantly increased in model group (P< 0.05). Electroacupuncture could significantly increase BBB score, neuron survival rate and expression of microRNA-21, reduce apoptotic rate of neurons and the ratio of Bax/Bcl-2, and inhibit the expression of Bax, Bcl-2 and cleaved Caspase-3 protein in tissues, which were significantly different from those of model group (P< 0.05). Conclusions: Electroacupuncture at Jiaji (EX-B2) points can significantly promote the recovery of neurological function in rats after ASCI, and its mechanism may be closely related to the up-regulation of the expression of microRNA-21 in tissues and the inhibition of the activation of Bax/Bcl-2/cleaved Caspase-3 signaling pathway. 展开更多
关键词 jiaji(EX-B2)points ELECTROACUPUNCTURE Acute spinal cord injury Apoptosis MICRORNA-21
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CLINICAL OBSERVATION ON THE THERAPEUTIC EFFECT OF ACUPUNCTURE OF JIAJI (EX-B2) IN THE TREATMENT OF APOPLECTIC SPASTIC HEMIPLEGIA
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作者 周君 谭源生 +2 位作者 梁云武 陈贵龙 王泽涛 《World Journal of Acupuncture-Moxibustion》 2005年第1期11-15,共5页
Objective: To compare the therape utic effects of acupuncture of different acupoints in the treatment of spast ic hemiplegia of apoplexy. Methods: Eighty stro ke patients with spastic hemiplegia were evenly randomized... Objective: To compare the therape utic effects of acupuncture of different acupoints in the treatment of spast ic hemiplegia of apoplexy. Methods: Eighty stro ke patients with spastic hemiplegia were evenly randomized into control grou p and treatment group. Forty cases of treatment group were given with acupun cture of Jiaji (夹脊 EX-B2) from T1 to L5, while forty cases of control gro up were treated with conventional acupoints as Jianyu (肩NFDA1 LI 15), Quchi (曲池 LI 11), Huantiao (环跳 GB 30), Zusanli (足三里 ST 36), Kunlun (昆仑 BL 60), etc. o n the diseased side, once daily, with 10 sessions being one therapeutic course, and 3 courses all together. The modified Ashworth Scale (MAS) and neurological d eficit grading scale (NDS) were used as the indexes to assess the therapeutic ef fects. Results: After treatment, the scores of NDS of both treat ment and control groups reduced and the difference value between post- and pre-treatment of tr ea tment group was significantly bigger than that of control group. MAS showed a si milar tendency in both groups. Of the 40 cases in treatment and control groups, 6 and 1 were cured, 20 and 15 had marked improvement, 9 and 11 had improvement, 4 and 8 failed, 1 and 5 got worse, with the total effective rates being 87.5% an d 67.5% respectively. The therapeutic effect of treatment group was significantl y superior to that of control group (P<0.01). Conc lusion: Acupuncture of Jiaji ( EX-B2) is superior to acupuncture of conventional acupoints in alleviating the state of spastic hemiplegia of apoplexy. 展开更多
关键词 Apoplectic spastic hemiplegia Acupuncture of jiaji (EX -B 2) Conventional acupoints
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Analysis on the Characteristics of the Co-seismic Response of Water Levels in the Jiaji Well
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作者 Gu Shenyi Liu Yang +2 位作者 Zhang Hui Xie Xiaojing Ye Xiangding 《Earthquake Research in China》 2012年第1期73-86,共14页
In this study, we analyze the co-seismic response of water levels in the Jiaji well to strong earthquakes (Ms ≥7. 8) from 2001 to 2010 at an epicentrai distance less than 8000km. We investigated the co-seismic vari... In this study, we analyze the co-seismic response of water levels in the Jiaji well to strong earthquakes (Ms ≥7. 8) from 2001 to 2010 at an epicentrai distance less than 8000km. We investigated the co-seismic variation form of water levels, and analyzed the relationship between the amplitude of water level variation and the magnitude and the epicentral distance. We then checked the seismic wave phases when the changes of water level occurred. It was shown that: (1) the water level's co-seismic response is mainly characterized by escalation with no oscillation; (2) the amplitude of water level change has a certain connection with epicentral distance and magnitude; (3) co-seismic response of water levels in the Jiaji well shows a certain directivity; (4) most of the co-seismic responses were caused by surface waves, and some by long-period S waves. 展开更多
关键词 Water level Co-seismic response to strong earthquakes jiaji well in Hainan
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电针联合悬吊训练治疗慢性非特异性下腰痛的临床观察
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作者 李国华 黎村丰 莫佳琪 《上海针灸杂志》 2026年第1期52-58,共7页
目的观察电针联合悬吊训练(sling exercise therapy,SET)治疗慢性非特异性下腰痛(chronic nonspecific low back pain,CNLBP)的临床疗效。方法将72例CNLBP患者随机分为观察组和对照组,每组36例。对照组行SET治疗,观察组在对照组基础上... 目的观察电针联合悬吊训练(sling exercise therapy,SET)治疗慢性非特异性下腰痛(chronic nonspecific low back pain,CNLBP)的临床疗效。方法将72例CNLBP患者随机分为观察组和对照组,每组36例。对照组行SET治疗,观察组在对照组基础上采用电针腰夹脊穴治疗。观察两组治疗前后视觉模拟评分法(visual analog scale,VAS)、腰椎功能障碍指数(oswestry disability index,ODI)、日本骨科协会(Japanese Orthopaedc Association,JOA)评分的变化,并比较两组治疗前后竖脊肌、多裂肌表面肌电图(surface electromyography,sEMG)中的指标均方根值(root mean square,RMS)和中位频率值(median frequency value,MF)。结果两组治疗2周后VAS、ODI评分低于治疗前,治疗后VAS、ODI评分低于治疗2周后和治疗前,差异有统计学意义(P<0.05);观察组治疗2周后和治疗后VAS、ODI评分低于对照组,差异有统计学意义(P<0.05)。两组治疗2周后JOA评分高于治疗前,治疗后JOA评分高于治疗2周后和治疗前,差异有统计学意义(P<0.05);观察组治疗2周后和治疗后JOA评分高于对照组,差异有统计学意义(P<0.05)。对照组竖脊肌、多裂肌双侧RMS值治疗2周后与治疗前比较,差异无统计学意义(P>0.05);治疗后竖脊肌、多裂肌双侧RMS值高于治疗2周后和治疗前,差异有统计学意义(P<0.05);观察组治疗2周后竖脊肌、多裂肌双侧RMS值高于治疗前,治疗后竖脊肌、多裂肌双侧RMS值高于治疗2周后和治疗前,差异有统计学意义(P<0.05);观察组治疗2周后、治疗后竖脊肌和多裂肌双侧RMS值高于对照组,差异有统计学意义(P<0.05)。两组治疗2周后竖脊肌、多裂肌双侧MF值高于治疗前,治疗后竖脊肌、多裂肌双侧MF值高于治疗2周后和治疗前,差异有统计学意义(P<0.05);观察组治疗2周后和治疗后竖脊肌、多裂肌双侧MF值高于对照组,差异有统计学意义(P<0.05)。结论电针联合SET训练能更好地减轻患者疼痛,改善椎旁核心肌(多裂肌、竖脊肌)的肌电信号,促进腰椎核心肌群功能恢复。 展开更多
关键词 电针 夹脊 悬吊训练 下腰痛 椎旁核心肌 表面肌电信号
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Clinical observation on acupuncture at Jiaji(EX-B 2) points plus tuina in treating thoracic facet joint disorder 被引量:3
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作者 周伟成 诸剑芳 《Journal of Acupuncture and Tuina Science》 CSCD 2016年第2期126-130,共5页
Objective: To observe the clinical effects of acupuncture at Jiaji (EX-B 2) points plus tuina manipulation for thoracic facet joint disorder, and get new clinical evidence for treatment of thoracic facet joint diso... Objective: To observe the clinical effects of acupuncture at Jiaji (EX-B 2) points plus tuina manipulation for thoracic facet joint disorder, and get new clinical evidence for treatment of thoracic facet joint disorder. Methods: Totally 106 patients with thoracic facet joint disorder were randomly allocated into an observation group and a control group based on the random number table. Patients in the control group were treated by tuina manipulation, while those in the observation group were treated by acupuncture at Jiaji (EX-B 2) points before tuina manipulation. Patients in the two groups were treated once a day. The improvements of signs and symptoms and the efficacy were observed after 3 treatments. Results: After treatment, there were intra-group statistical differences in scores of 8 signs and symptoms in both groups (P〈0.01}; the score of each item in the observation group was lower than that in the control group, and there was statistical significance in the inter-group difference (P〈0.05). The cure rate of the observation group was 50.9%, versus 26.4% in the control group, and there was a significant difference between the two groups (P〈0.05). Conclusion: In treating thoracic facet joint disorder, acupuncture plus tuina manipulation can restore the biomechanical balance of thoracic vertebrae, fully maximized the combined effect, and significantly improve the clinical efficacy. 展开更多
关键词 Acupuncture Therapy Point jiaji (EX-B 2) TUINA MASSAGE Manipulation Spinal Thoracic Vertebrae Zygapophyseal Joint
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基于“通督滋阳”理论探讨夹脊电针调控脊髓损伤“铁死亡-炎症反应”机制研究
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作者 栾逸先 朱荟一 +5 位作者 孙忠人 柯维华 王丽娟 伊思锐 朱嘉民 田洪昭 《针灸临床杂志》 2026年第1期7-11,共5页
夹脊电针可通过干预脊髓损伤后受损区域神经细胞自噬、氧化应激、焦亡与炎性反应等机制促进运动功能恢复,诸多研究表明夹脊电针具体通过调控铁死亡Xc^(-)/GPX4通路,使局部铁死亡相关因子GSH、GPX4表达升高,抑制神经元死亡,保护神经元存... 夹脊电针可通过干预脊髓损伤后受损区域神经细胞自噬、氧化应激、焦亡与炎性反应等机制促进运动功能恢复,诸多研究表明夹脊电针具体通过调控铁死亡Xc^(-)/GPX4通路,使局部铁死亡相关因子GSH、GPX4表达升高,抑制神经元死亡,保护神经元存活,并且影响HMGB1的含量从而抑制NLRP3炎症小体活化。该机制与中医“通督滋阳”治疗人体阴阳不和的理论相契合,夹脊电针取穴选择督脉及膀胱经相关腧穴,可通过调动一身之阳气促进疾病康复。随着对电针治疗脊髓损伤理论基础的深入研究,将“通督滋阳”理论从分子生物学角度进行阐释,进而验证电针治疗脊髓损伤的多靶点性。 展开更多
关键词 脊髓损伤 夹脊穴 电针 铁死亡 炎症反应 通督滋阳
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Acupuncture-moxibustion at Jiaji(EX-B 2) points for intervertebral disc herniation: a systematic review 被引量:2
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作者 洪珏 刘婕 +3 位作者 张翠红 黄琴峰 吴凌翔 黄颖 《Journal of Acupuncture and Tuina Science》 CSCD 2015年第4期217-221,共5页
By organizing and classifying the literatures related to acupuncture-moxibustion at Jiaji (EX-B 2) points in treating intervertebral disc herniation (IDH) published before December 32, 2013, to summarize the appli... By organizing and classifying the literatures related to acupuncture-moxibustion at Jiaji (EX-B 2) points in treating intervertebral disc herniation (IDH) published before December 32, 2013, to summarize the application status and features of Jiaji (EX-B 2) points. It's found that its most favorable indication is IDH. It also further analyzed the action mechanism of acupuncture-moxibustion at Jiaji (EX-B 2) points in treating IDH, and brought up some ideas to highlight the further study. 展开更多
关键词 Point jiaji (EX-B 2) Intervertebral Disc Displacement Intervertebral Disc Degeneration Acupuncture- moxibustion Therapy Acupuncture Therapy Review
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Observation on Therapeutic Effects of Electroacupuncture at Jiaji (Ex-B 2) Points plus Herbal Medicine for Herpes Zoster 被引量:3
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作者 王智娟 邹勇 黄国琪 《Journal of Acupuncture and Tuina Science》 2012年第5期313-317,共5页
Objective: To observe the clinical effects of electroacupuncture (EA) at Jiaji (Ex-B 2) points plus herbal medicine for herpes zoster (HZ). Methods: Sixty-two cases were randomly divided into a treatment group... Objective: To observe the clinical effects of electroacupuncture (EA) at Jiaji (Ex-B 2) points plus herbal medicine for herpes zoster (HZ). Methods: Sixty-two cases were randomly divided into a treatment group and a control group. The treatment group was treated with EA at Jiaji (Ex-B 2) points plus herbal medicine based upon the pattern differentiation. The control group was treated with oral administration of Aciclovir tablets for resisting virus, and Mecobalamin tablets for nourishing the nerves and Aciclovir cream for skin rash. The therapeutic effects were compared between the two groups, after two-week treatment Results: After 7 d of the treatment, the therapeutic effect was remarkably better in the treatment group than that in the control group (P〈0.01). After two-week treatment, the therapeutic effects were still different between the two groups (P〈0.05). Conclusion: The therapeutic effect of EA at Jiaji (Ex-B 2) points plus herbal medicine for HZ is better than that of Western medications in resisting virus and nourishing nerves. 展开更多
关键词 ELECTROACUPUNCTURE Acupuncture Therapy Acupuncture Medication Combined Herpes Zoster Points jiaji (Ex-B 2)
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夹脊电针对脊髓损伤大鼠脊髓组织小胶质细胞极化及炎性反应的影响
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作者 覃业校 孙洪艺 +1 位作者 李晓宁 李庆琳 《广州中医药大学学报》 2026年第1期166-174,共9页
【目的】观察夹脊电针对脊髓损伤大鼠的治疗作用及机制。【方法】将48只SD大鼠随机分为假手术组、模型组、夹脊电针组、夹脊电针+单钠尿酸盐(MSU)[NOD样受体热蛋白结构域相关蛋白3(NLRP3)激活剂]组,每组分为3、7 d两个亚组,每个时间点6... 【目的】观察夹脊电针对脊髓损伤大鼠的治疗作用及机制。【方法】将48只SD大鼠随机分为假手术组、模型组、夹脊电针组、夹脊电针+单钠尿酸盐(MSU)[NOD样受体热蛋白结构域相关蛋白3(NLRP3)激活剂]组,每组分为3、7 d两个亚组,每个时间点6只大鼠。除假手术组,其他各组大鼠采用改良Allen’s法制备脊髓损伤模型。夹脊电针组大鼠取双侧T9、T11夹脊穴电针治疗。夹脊电针+MSU组腹腔注射MSU,再进行夹脊穴电针治疗。分别治疗3、7 d后取材。采用BBB评分评价大鼠运动功能,苏木精-伊红(HE)染色法观察各组大鼠脊髓组织病理形态,免疫荧光双标法检测大鼠离子钙接头蛋白1(Iba-1)与M1小胶质细胞标志物诱导型一氧化氮合酶(iNOS)以及Iba-1与M2小胶质细胞标志物精氨酸酶1(Arg-1)在脊髓组织中的表达及定位情况。进一步采用Western Blot法检测大鼠脊髓组织Iba-1、iNOS、Arg-1、白细胞介素1β(IL-1β)的蛋白表达水平。【结果】(1)与假手术组比较,模型组大鼠于干预3、7 d时BBB评分降低(P<0.05);与模型组比较,夹脊电针组于干预3、7 d BBB评分升高(P<0.05);夹脊电针+MSU组BBB评分低于夹脊电针组。(2)模型组大鼠脊髓组织可见出血区,并有炎性细胞浸润;夹脊电针组脊髓组织炎性细胞浸润减少。(3)与假手术组比较,模型组Iba-1与iNOS共表达荧光强度升高(P<0.05),Iba-1与Arg-1共表达荧光强度下降(P<0.05);与模型组比较,夹脊电针组2个时间点Iba-1与iNOS共表达荧光强度降低(P<0.05),Iba-1与Arg-1共表达荧光强度升高(P<0.05)。MSU干预对电针治疗效果有抑制作用。(4)与假手术组比较,模型组Iba-1、iNOS、IL-1β的蛋白表达水平升高(P<0.05),Arg-1蛋白表达水平下降(P<0.05);与模型组比较,夹脊电针组脊髓组织Iba-1、iNOS、IL-1β蛋白表达水平降低(P<0.05),Arg-1蛋白表达水平升高(P<0.05)。【结论】夹脊电针能够提高脊髓损伤大鼠运动功能,其机制可能与调控NLRP3继而抑制小胶质细胞M1极化及炎性物质释放、促进M2极化有关。 展开更多
关键词 夹脊电针 脊髓损伤 小胶质细胞 M1极化 M2极化 大鼠
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基于P2X7R介导的细胞焦亡途径分析夹脊电针对脊髓损伤大鼠神经细胞焦亡及轴突再生和功能恢复的影响
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作者 李超男 李水琴 +3 位作者 薛阳 贺斌彦 胡丽艳 李青 《针灸临床杂志》 2026年第1期86-91,共6页
目的:探究基于P2X7R介导的细胞焦亡途径分析夹脊电针对脊髓损伤大鼠神经细胞焦亡及轴突再生和功能恢复的影响。方法:选取50只SPF级SD雄性大鼠,随机分为正常组、模型组、NC组、P2X7R siRNA组和夹脊电针组,每组10只,对模型组、NC组、P2X7R... 目的:探究基于P2X7R介导的细胞焦亡途径分析夹脊电针对脊髓损伤大鼠神经细胞焦亡及轴突再生和功能恢复的影响。方法:选取50只SPF级SD雄性大鼠,随机分为正常组、模型组、NC组、P2X7R siRNA组和夹脊电针组,每组10只,对模型组、NC组、P2X7R siRNA组及夹脊电针组进行脊髓损伤建模,正常组不建立该模型,建模成功后,对NC组尾静脉注射200 nmol/kg NC siRNA慢病毒,对P2X7R siRNA组尾静脉注射200 nmol/kg P2X7R siRNA慢病毒,对夹脊电针组给予夹脊电针治疗,正常组、模型组不做处理,水平楼梯实验、圆筒攀爬探索实验及BBB评分评价功能恢复,HE染色法检测脊髓组织病理形态,TUNEL法检测细胞焦亡,免疫印迹法检测轴突再生相关指标,免疫组化法检测P2X7R表达。结果:与正常组比较,模型组踏空错误率、细胞焦亡率及脊髓组织P2X7R表达升高,差异具有统计学意义(P<0.05),肢体使用频率、BBB评分、脊髓组织GFAP及NF-200蛋白表达降低,差异具有统计学意义(P<0.05);与模型组比较,NC组踏空错误率、肢体使用频率、BBB评分、细胞焦亡率、脊髓组织GFAP、NF-200蛋白表达及脊髓组织P2X7R表达比较,差异无统计学意义(P>0.05);与NC组相比,P2X7R siRNA组、夹脊电针组踏空错误率、细胞焦亡率及脊髓组织P2X7R表达降低,差异具有统计学意义(P<0.05),肢体使用频率、BBB评分、脊髓组织GFAP及NF-200蛋白表达升高,差异具有统计学意义(P<0.05),且P2X7R siRNA组与夹脊电针组比较,差异无统计学意义(P>0.05);正常组脊髓组织细胞形态规则,结构清晰,灰质白质界限分明,模型组、NC组脊髓组织可见细胞肿胀、坏死,结构紊乱,灰质白质界限模糊,呈现明显病理改变,与模型组、NC组比较,P2X7R siRNA组及夹脊电针组病理结构明显改善。结论:夹脊电针对脊髓损伤具有显著疗效,可有效改善神经细胞焦亡,并促进轴突再生和功能恢复,其机制可能与抑制P2X7R激活有关。 展开更多
关键词 脊髓损伤 夹脊穴 电针 神经细胞焦亡 轴突再生 功能恢复 P2X7R
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电针夹脊穴联合筋膜刀治疗飞行人员腰肌劳损的临床研究
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作者 李艾穆 《中外医学研究》 2026年第3期52-56,共5页
目的:探析电针夹脊穴联合筋膜刀治疗飞行人员腰肌劳损的效果。方法:选择2021年9月—2024年8月期间样本医院接诊的80例飞行人员腰肌劳损患者,按随机数表法分为观察组和对照组,每组各40例。两组均接受一般治疗,在此基础上对照组予电针夹... 目的:探析电针夹脊穴联合筋膜刀治疗飞行人员腰肌劳损的效果。方法:选择2021年9月—2024年8月期间样本医院接诊的80例飞行人员腰肌劳损患者,按随机数表法分为观察组和对照组,每组各40例。两组均接受一般治疗,在此基础上对照组予电针夹脊穴治疗,观察组予电针夹脊穴联合筋膜刀治疗,两组均治疗4周。比较两组疗效,治疗前后疼痛情况[采用疼痛数字评价量表(NRS)评估]、竖脊肌表面肌电信号、腰椎功能、生活质量,治疗后随访6个月,统计复发情况。结果:观察组治疗总有效率高于对照组,且观察组整体疼痛程度低于对照组,差异有统计学意义(P<0.05);两组平均肌电波幅(AEMG)、平均功率频率(MPF)水平、健康状况调查问卷(SF-36)各维度评分均高于治疗前,且观察组AEMG、MPF水平、SF-36各维度评分均高于对照组,差异有统计学意义(P<0.05);两组Oswestry功能障碍指数(ODI)评分均低于治疗前,且观察组ODI评分低于对照组,差异有统计学意义(P<0.05);随访期间,观察组和对照组的复发率比较,差异无统计学意义(P>0.05)。结论:电针夹脊穴联合筋膜刀治疗飞行人员腰肌劳损,能增强镇痛效果,显著改善患者竖脊肌肌力、腰椎功能及生活质量。 展开更多
关键词 飞行员 腰肌劳损 夹脊穴 电针 筋膜刀 腰椎功能
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针刺颈夹脊穴联合牵引对颈椎病气滞血瘀证患者椎动脉血流和颈椎生理曲度的影响
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作者 王子亮 苏宁 贺孝勇 《中医药信息》 2026年第2期76-80,共5页
目的观察针刺颈夹脊穴联合牵引对颈椎病气滞血瘀证患者椎动脉血流和颈椎生理曲度的影响。方法选取符合纳入标准的颈椎病气滞血瘀证患者,依据随机数字表随机分为对照组和观察组,每组各55例。对照组口服非甾体抗炎药和营养神经药,观察组... 目的观察针刺颈夹脊穴联合牵引对颈椎病气滞血瘀证患者椎动脉血流和颈椎生理曲度的影响。方法选取符合纳入标准的颈椎病气滞血瘀证患者,依据随机数字表随机分为对照组和观察组,每组各55例。对照组口服非甾体抗炎药和营养神经药,观察组给予针刺颈夹脊穴联合牵引治疗,两组均治疗30 d。比较两组患者治疗前后中医症状积分、椎动脉(基底动脉、右椎动脉、左椎动脉)血流速度、颈椎眩晕症状与功能评分(ESCV)、血清细胞因子(ET-1、TGF-β1、NO)、颈椎生理曲度影像参数(生理曲度值、椎体角度位移值、水平位移值)的变化情况,并比较临床疗效。结果治疗后,两组颈肩肢体疼痛、上肢麻木、颈项僵硬、肌肉紧张评分和椎体角度位移值、水平位移值、ET-1、TGF-β1水平均明显降低(P<0.05),基底动脉、右椎动脉、左椎动脉血流速度、NO水平、生理曲度值和ESCV各项评分和总得分均明显增加(P<0.05),且观察组上述指标的改善情况均优于对照组(P<0.05)。观察组总有效率98.2%(54/55),明显高于对照组85.5%(47/55)(P<0.05)。结论针刺夹脊穴联合牵引治疗颈椎病气滞血瘀证,可减轻患者疼痛情况,改善颈肩部不适症状,优化颈椎生理曲度影像学参数和颈动脉血流参数。 展开更多
关键词 椎动脉血流 颈椎生理曲度 针刺 颈夹脊穴 牵引
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葛根汤加减联合针刺颈夹脊穴治疗椎动脉型颈椎病临床观察
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作者 史诚智 张欣 田壮伟 《河南中医》 2026年第2期194-199,共6页
目的:观察葛根汤加减联合针刺颈夹脊穴治疗椎动脉型颈椎病的临床疗效。方法:选取2022年1月至2024年10月河南省胸科医院南院区中医科收治的椎动脉型颈椎病患者110例,按照随机数字表法分为针刺组和针药组,每组各55例。两组均给予常规按摩... 目的:观察葛根汤加减联合针刺颈夹脊穴治疗椎动脉型颈椎病的临床疗效。方法:选取2022年1月至2024年10月河南省胸科医院南院区中医科收治的椎动脉型颈椎病患者110例,按照随机数字表法分为针刺组和针药组,每组各55例。两组均给予常规按摩和颈部牵引治疗,同时给予盐酸氟桂利嗪胶囊治疗,针刺组另给予针刺颈夹脊穴治疗,针药组另给予葛根汤加减联合针刺颈夹脊穴治疗。观察两组治疗前后椎动脉(vertebral artery,VA)和基底动脉(basilar artery,BA)收缩期峰流速(peak systolic velocity,Vs)、舒张末期峰流速(end diastolic velocity,Vd)、平均流速(mean velocity,Vm)及髓样分化因子88(Myeloid Differentiation Factor 88,MyD88)、Toll样受体-4(Toll like receptor-4,TLR-4)、肿瘤坏死因子(tumor necrosis factor,TNF)-α、白细胞介素(interleukin,IL)-1β、IL-6、一氧化氮(nitric oxide,NO)水平,评估两组治疗前后中医症状评分、眩晕评分及不良反应发生情况。结果:两组治疗后VA和BA的Vs、Vd、Vm均高于治疗前,且针药组高于针刺组,差异有统计学意义(P<0.05)。两组治疗后TLR-4、MyD88水平均低于治疗前,且针药组治疗后TLR-4、MyD88水平低于针刺组,差异有统计学意义(P<0.05)。两组治疗后TNF-α、IL-1β、IL-6、NO水平均低于治疗前,且针药组治疗后TNF-α、IL-1β、IL-6、NO水平均低于针刺组,差异有统计学意义(P<0.05)。两组治疗后中医症状评分均低于治疗前,且针药组低于针刺组,差异有统计学意义(P<0.05);两组治疗后眩晕评分均高于治疗前,且针药组高于针刺组,差异有统计学意义(P<0.05)。针刺组不良反应发生率为7.27%,针药组不良反应发生率为12.73%,两组不良反应比较差异无统计学意义(P > 0.05)。结论:葛根汤加减联合针刺颈夹脊穴治疗椎动脉型颈椎病,可调节TLR-4/MyD88信号通路,改善血流动力学,减轻症状。 展开更多
关键词 椎动脉型颈椎病 葛根汤 针刺 颈夹脊穴 TLR-4/MyD88信号通路 血流动力学 《伤寒论》 张仲景
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针刺夹脊穴联合益气补血利水汤治疗脑梗死后遗症患者的疗效观察
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作者 高彩丽 付春爱 +2 位作者 高莉 李蕾 刘晶 《广州中医药大学学报》 2026年第1期110-116,共7页
【目的】观察针刺夹脊穴联合益气补血利水汤治疗脑梗死后遗症患者的临床疗效。【方法】选取2021年6月至2023年6月延安市中医医院针灸科收治的129例明确诊断为脑梗死后遗症期的患者为研究对象。按随机数字表将患者随机分为针刺组,汤药组... 【目的】观察针刺夹脊穴联合益气补血利水汤治疗脑梗死后遗症患者的临床疗效。【方法】选取2021年6月至2023年6月延安市中医医院针灸科收治的129例明确诊断为脑梗死后遗症期的患者为研究对象。按随机数字表将患者随机分为针刺组,汤药组和联合组共3组,每组各43例。针刺组给予针刺夹脊穴治疗,汤药组给予益气补血利水汤治疗,联合组给予针刺夹脊穴联合益气补血利水汤治疗。治疗1个月为1个疗程,3组患者均治疗3个疗程。治疗3个月后,评价3组临床疗效。观察3组患者治疗前后汉语失语症评定量表(ABC)评分、Fugl-Meyer运动功能评估量表(FMA)评分的变化情况,以及标准吞咽功能评价量表(SSA)、吞咽障碍功能评分量表(FDS)、进食评估问卷调查工具10(EAT-10)的情况。比较2组患者治疗前后脑损伤标志物包括胶质纤维酸性蛋白(GFAP)、中枢神经特异蛋白(S100-β)、神经元烯醇化酶(NSE)水平的变化情况,以及下肢肌群表面肌电图指标的情况。【结果】(1)针刺组总有效率为72.09%(31/43),汤药组为74.42%(32/43),联合组为90.70%(39/43)。联合组疗效优于针刺组和汤药组,差异有统计学意义(P<0.05)。(2)治疗后,3组患者的ABC量表评分、吞咽功能评分、FMA评分均明显改善,且联合组ABC各项评分、吞咽功能评分、FMA评分均明显优于针刺组和汤药组,差异有统计学意义(P<0.05)。(3)治疗后,3组患者的脑损伤标志物水平均明显改善(P<0.05),且联合组在改善脑损伤标志物水平方面明显优于针刺组和汤药组,差异有统计学意义(P<0.05)。(4)治疗后,3组患者的表面肌电图指标均明显改善(P<0.05),且联合组在改善表面肌电图指标方面明显优于针刺组和汤药组,差异有统计学意义(P<0.05)。【结论】针刺夹脊穴联合益气补血利水汤治疗脑梗死后遗症,能够明显地改善患者的语言、吞咽和运动功能,抑制脑损伤标志物的表达,改善患者下肢肌肉神经系统功能,具有良好的康复效果。 展开更多
关键词 针刺夹脊穴 益气补血利水汤 脑梗死后遗症 语言功能 吞咽功能 肢体运动功能 脑损伤标志物 肌电图 临床观察
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Effects of electroacupuncture at “Jiaji ” (EX-B 2) on myocardial apoptosis and the expression of Bcl-2 and Bax in rats with ischemia-reperfusion injury
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作者 孙素平 《China Medical Abstracts(Internal Medicine)》 2013年第3期134-134,共1页
Objective To explore the protective mechanism of acupuncture on myocardial ischemia-reperfusion injury.Methods Fifty Wistar rats were randomly divided into a sham-operation group,a model group,a Jiaji group,a Neiguan ... Objective To explore the protective mechanism of acupuncture on myocardial ischemia-reperfusion injury.Methods Fifty Wistar rats were randomly divided into a sham-operation group,a model group,a Jiaji group,a Neiguan group and a Yanglingquan group,10-rats 展开更多
关键词 acupuncture protective INHIBITING Apoptosis EX-B 2 jiaji creased ADJUSTING
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Effect of Jiaji electroacupuncture in transected rat spinal cord 被引量:2
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作者 XiuYing Teng DeSheng Wang +8 位作者 XiaoMei Zhang ZengJiao Lai HaiXia Jiang JianLi Wu Huan Qi Qian Yu Shun Yao WenBo Song et al. 《Chinese Science Bulletin》 SCIE EI CAS 2012年第7期762-768,共7页
We evaluated the effect of Jiaji electroacupuncture on cell proliferation and the expression of markers of endogenous neural stem cell activation after complete spinal cord transection. Female Wistar rats were assigne... We evaluated the effect of Jiaji electroacupuncture on cell proliferation and the expression of markers of endogenous neural stem cell activation after complete spinal cord transection. Female Wistar rats were assigned to 4 groups (n = 24 each): a sham-operated group, a control group, a Jiaji electroacupuncture group, and a Jiaji electroacupuncture preconditioning group. Motor function was significantly improved in the acupuncture groups compared to the control group at 7 and 14 d. Numbers of bromodeoxyuridine (BrdU)-, nestin-, and glial fibrillary acidic protein (GFAP)-positive cells were significantly greater in the acupuncture groups than in the controls at each time point. Expression of nestin and GFAP mRNA was significantly higher in the acupuncture groups than in the controls at each time point. Thus, Jiaji electroacupuncture and preconditioning may promote the proliferation of endogenous neural stem cells after spinal cord transection. 展开更多
关键词 WISTAR大鼠 脊髓 胶质纤维酸性蛋白 神经干细胞 NESTIN 细胞增殖 GFAP 细胞活化
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基于“脑-心-肾-精室”轴探讨针刺华佗夹脊穴治疗慢性前列腺炎的机制 被引量:1
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作者 刘洋 高庆和 +1 位作者 骆第铖 郭军 《中国性科学》 2025年第5期67-70,共4页
“脑-心-肾-精室”轴、华佗夹脊穴与慢性前列腺炎三者密切相关,且相互作用机制复杂。轴与华佗夹脊穴走形相伴、生理功能高度契合,轴任何环节出现问题均可影响慢性前列腺炎的发生发展,而华佗夹脊穴在功能上与轴有着一致性。通过针刺华佗... “脑-心-肾-精室”轴、华佗夹脊穴与慢性前列腺炎三者密切相关,且相互作用机制复杂。轴与华佗夹脊穴走形相伴、生理功能高度契合,轴任何环节出现问题均可影响慢性前列腺炎的发生发展,而华佗夹脊穴在功能上与轴有着一致性。通过针刺华佗夹脊穴能有效改善轴失衡的状态,且现代机制表明,针刺华佗夹脊穴可通过调节中枢、改善局部炎症、调节内分泌等机制干预慢性前列腺炎进程。故华佗夹脊穴可成为针刺治疗慢性前列腺炎的新切入点。 展开更多
关键词 慢性前列腺炎 “脑-心-肾-精室”轴 针刺 华佗夹脊穴 机制
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