This work describes an effective Pd-catalyzed isomerization-hydroformylation of internal olefins with HCO_(2)H and N-formylsaccharin,providing a wide variety of linear aldehydes in up to 72%yield with up to 18:1 l/b r...This work describes an effective Pd-catalyzed isomerization-hydroformylation of internal olefins with HCO_(2)H and N-formylsaccharin,providing a wide variety of linear aldehydes in up to 72%yield with up to 18:1 l/b ratio.The olefin substrate can bear various functional groups.Conjugated olefins can also be efficiently isomerized and hydroformylated.The reaction is easy to operate and requires no handling of CO and H_(2).To the best of our knowledge,the current process represents the first example for Pd-catalyzed efficient isomerization-hydroformylation process of internal olefins to predominately give linear aldehydes.展开更多
基金supported by the National Natural Science Foundation of China(22271024,21632005)the Natural Science Foundation of Jiangsu Province(BK20190929)Changzhou University.
文摘This work describes an effective Pd-catalyzed isomerization-hydroformylation of internal olefins with HCO_(2)H and N-formylsaccharin,providing a wide variety of linear aldehydes in up to 72%yield with up to 18:1 l/b ratio.The olefin substrate can bear various functional groups.Conjugated olefins can also be efficiently isomerized and hydroformylated.The reaction is easy to operate and requires no handling of CO and H_(2).To the best of our knowledge,the current process represents the first example for Pd-catalyzed efficient isomerization-hydroformylation process of internal olefins to predominately give linear aldehydes.
