Phenanthridine is a key structural motif in numerous natural products and biologically active compounds,making it an attractive target for pharmaceuticals and advanced materials.Recently,visible-light-induced cyclizat...Phenanthridine is a key structural motif in numerous natural products and biologically active compounds,making it an attractive target for pharmaceuticals and advanced materials.Recently,visible-light-induced cyclization through radical process has emerged as a powerful and sustainable strategy for building such a core under mild and environmentally friendly conditions,paving the way for new applications in synthetic and medicinal chemistry.This review highlights recent progress in the photochemical synthesis of phenanthridines,mainly focusing on various radical acceptors,including 2-isocyanobiaryls,cyanides,vinyl azides and vinyl benzotriazoles.展开更多
基金financially supported by the National Natural Science Foundation of China(No.21602046)the Zhongjing Youth Talent Project from Henan University of Chinese Medicine(No.03104150-2024-1-52)the Foundation for University Key Teachers from the Education Department of Henan Province(No.2020GGJS107)。
文摘Phenanthridine is a key structural motif in numerous natural products and biologically active compounds,making it an attractive target for pharmaceuticals and advanced materials.Recently,visible-light-induced cyclization through radical process has emerged as a powerful and sustainable strategy for building such a core under mild and environmentally friendly conditions,paving the way for new applications in synthetic and medicinal chemistry.This review highlights recent progress in the photochemical synthesis of phenanthridines,mainly focusing on various radical acceptors,including 2-isocyanobiaryls,cyanides,vinyl azides and vinyl benzotriazoles.
