目的探讨基于亚洲肌肉减少症工作组专家共识(AWGS)的4种筛查工具[简易五项问卷(SARC-F)、SARC-Calf问卷、小腿围(CC)、石井评分(Ishii评分)]对中国老年人肌肉减少症(肌少症)的诊断价值。方法计算机检索Web of Science、PubMed、EMBase、...目的探讨基于亚洲肌肉减少症工作组专家共识(AWGS)的4种筛查工具[简易五项问卷(SARC-F)、SARC-Calf问卷、小腿围(CC)、石井评分(Ishii评分)]对中国老年人肌肉减少症(肌少症)的诊断价值。方法计算机检索Web of Science、PubMed、EMBase、CNKI、WanFang Data数据库,搜集有关肌少症筛查工具准确性的诊断性试验,检索时限为建库至2023年4月。由2名研究者独立筛选文献、提取资料并交叉核对,并评价纳入研究的质量。采用Meta-disc 1.4和Stata 17.0软件进行Meta分析。结果共纳入18个研究,涉及4种筛查工具。基于AWGS诊断标准,在中国老年人中SARC-F、SARC-Calf、CC、Ishii评分的灵敏度分别为19%、58%、82%、92%,特异度为93%、84%、72%、71%,曲线下面积(AUC)为0.76、0.77、0.85、0.88,SARC-F、SARC-Calf、CC应用于女性的灵敏度比男性高,特异度比男性低,Ishii评分与之相反。SARC-F、Ishii评分在养老机构和住院患者中具有更高的灵敏度,分别为39%、95%。SARC-Calf在社区居民中具有更高特异度(87%)。CC在社区居民中具有更高的灵敏度、特异度,分别为84%、76%。结论SARC-F、Ishii评分更适合在养老机构和住院患者中筛查肌少症,CC更适合在社区居民中筛查肌少症,SARC-F、SARC-Calf可作为排除肌少症患者的工具。SARC-F、SARC-Calf、CC在女性中的应用价值较男性高,Ishii评分与之相反。展开更多
Objectives:Early identification of sarcopenia in patients with chronic liver disease is crucial for patient management and prevention of severe complications.We aimed to assess the effectiveness of Ishii score,Strengt...Objectives:Early identification of sarcopenia in patients with chronic liver disease is crucial for patient management and prevention of severe complications.We aimed to assess the effectiveness of Ishii score,Strength,Assistance with Walking,Rise from a Chair,Climb Stairs and Falls(SARC-F),SARC-F and Calf Circumference(SARC-CalF),and Mini Sarcopenia Risk Assessment-7(MSRA-7)to screen sarcopenia in patients with chronic liver disease.Methods:This prospective study included patients with chronic liver disease in the infectious department of a tertiary hospital in Sichuan,China.Ishii score,SARC-F,SARC-CalF,and MSRA-7 were used to screen for sarcopenia risk.Sarcopenia was diagnosed according to the Asian Myometriosis Working Group(AWGS)2019,which was used as the gold standard to compare the performance of the four screening tools.We completed clinical registration on the Chinese Clinical Trial Registration website(ChiCTR2100043910).Results:A total of 366 patients with chronic liver disease(22.4%women,mean age 48.96±11.88 years)were evaluated.Based on the AWGS 2019 standard,the prevalence of sarcopenia in patients with chronic liver disease was 17.5%.Among all participants,receiver operating characteristic(ROC)produced an area under the curve(AUC)of 0.82 for Ishii score(sensitivity 85.94%,specificity 78.15%),0.53 for SARC-F(sensitivity 6.25%,specificity 99.34%),0.64 for SARC-CalF(sensitivity 45.31%,specificity 83.11%),and 0.55 for MSRA-7(sensitivity 87.50%,specificity 22.85%).Based on AUC,decision curve analysis,and calibration curves,we concluded that Ishii score was the most accurate screening tool and was superior to the other tools.Conclusions:Ishii score is more suitable for screening sarcopenia in patients with chronic liver disease than the SARC-F,SARC-CalF,and MSRA-7,based on the AWGS 2019 criteria.Nursing professionals can use Ishii score as a clinical tool to screen for sarcopenia in patients with chronic liver disease,providing an indication cue for the final diagnosis of sarcopenia,improving diagnostic efficiency,and enabling early identification and prevention of complications resulting from sarcopenia.展开更多
In this paper, we use the optimum interpolation sea surface temperature (OISST) provided by the National Center for Environmental Prediction (NCEP) to replace the temperature in the top three layers in the ISHII data,...In this paper, we use the optimum interpolation sea surface temperature (OISST) provided by the National Center for Environmental Prediction (NCEP) to replace the temperature in the top three layers in the ISHII data, and make use of the modified ISHII temperature data to calculate the thermosteric sea level (called modified steric sea level (SSL) hereafter). We subtract the modified SSL and the steric sea level (called ordinary SSL hereafter) derived from the ISHII temperature and salinity from the steric sea level (SSL) provided by the Gravity Recovery and Climate Experiment (GRACE), respectively, and find that the rms error of the difference of the former is obviously smaller than that of the latter. Therefore we reach the conclusion that under the assumption that the GRACE SSL is accurate, the modified SSL can reflect the true steric sea level more accurately. Making use of the modified SSL, we can find that the modified SSL in sea areas of different spatial scales shows an obvious rising trend in the upper 0-700 m layer for the period 1982-2006. The global mean SSL rises with a rate of 0.6 mm year-1 .The modified SSLs in sea areas of different spatial scales all show obvious oscillations with period of one year. There are oscillations with periods of 4-8 years in global oceans and with periods of 2-7 years in the Pacific. The Empirical Orthogonal Function method is applied to the sea areas of different spatial scales and we find that the first modes all have obvious 1-year period oscillations, the first mode of the global ocean has 4-8 year period oscillations, and that of the Pacific has 2-6 year period oscillations. The spatial distribution of the linear rising trend of the global modified SSL in the upper 0-700 m layer is inhomogeneous with intense regional characteristics. The modified SSL linear trend indicates a zonal dipole in the tropical Pacific, rising in the west and descending in the east. In the North Atlantic, the modified SSL indicates a meridional dipole, rising in the latitude band of 20°N-40°N and 45°N-65.5°N and descending obviously in the latitude band of 40°N-45°N.展开更多
文摘Objectives:Early identification of sarcopenia in patients with chronic liver disease is crucial for patient management and prevention of severe complications.We aimed to assess the effectiveness of Ishii score,Strength,Assistance with Walking,Rise from a Chair,Climb Stairs and Falls(SARC-F),SARC-F and Calf Circumference(SARC-CalF),and Mini Sarcopenia Risk Assessment-7(MSRA-7)to screen sarcopenia in patients with chronic liver disease.Methods:This prospective study included patients with chronic liver disease in the infectious department of a tertiary hospital in Sichuan,China.Ishii score,SARC-F,SARC-CalF,and MSRA-7 were used to screen for sarcopenia risk.Sarcopenia was diagnosed according to the Asian Myometriosis Working Group(AWGS)2019,which was used as the gold standard to compare the performance of the four screening tools.We completed clinical registration on the Chinese Clinical Trial Registration website(ChiCTR2100043910).Results:A total of 366 patients with chronic liver disease(22.4%women,mean age 48.96±11.88 years)were evaluated.Based on the AWGS 2019 standard,the prevalence of sarcopenia in patients with chronic liver disease was 17.5%.Among all participants,receiver operating characteristic(ROC)produced an area under the curve(AUC)of 0.82 for Ishii score(sensitivity 85.94%,specificity 78.15%),0.53 for SARC-F(sensitivity 6.25%,specificity 99.34%),0.64 for SARC-CalF(sensitivity 45.31%,specificity 83.11%),and 0.55 for MSRA-7(sensitivity 87.50%,specificity 22.85%).Based on AUC,decision curve analysis,and calibration curves,we concluded that Ishii score was the most accurate screening tool and was superior to the other tools.Conclusions:Ishii score is more suitable for screening sarcopenia in patients with chronic liver disease than the SARC-F,SARC-CalF,and MSRA-7,based on the AWGS 2019 criteria.Nursing professionals can use Ishii score as a clinical tool to screen for sarcopenia in patients with chronic liver disease,providing an indication cue for the final diagnosis of sarcopenia,improving diagnostic efficiency,and enabling early identification and prevention of complications resulting from sarcopenia.
基金supported by the National Natural Science Foundation of China (Grants 40806072, 40906002 and 41176009)Public Science and Technology Research Funds Projects of Ocean (201005019)
文摘In this paper, we use the optimum interpolation sea surface temperature (OISST) provided by the National Center for Environmental Prediction (NCEP) to replace the temperature in the top three layers in the ISHII data, and make use of the modified ISHII temperature data to calculate the thermosteric sea level (called modified steric sea level (SSL) hereafter). We subtract the modified SSL and the steric sea level (called ordinary SSL hereafter) derived from the ISHII temperature and salinity from the steric sea level (SSL) provided by the Gravity Recovery and Climate Experiment (GRACE), respectively, and find that the rms error of the difference of the former is obviously smaller than that of the latter. Therefore we reach the conclusion that under the assumption that the GRACE SSL is accurate, the modified SSL can reflect the true steric sea level more accurately. Making use of the modified SSL, we can find that the modified SSL in sea areas of different spatial scales shows an obvious rising trend in the upper 0-700 m layer for the period 1982-2006. The global mean SSL rises with a rate of 0.6 mm year-1 .The modified SSLs in sea areas of different spatial scales all show obvious oscillations with period of one year. There are oscillations with periods of 4-8 years in global oceans and with periods of 2-7 years in the Pacific. The Empirical Orthogonal Function method is applied to the sea areas of different spatial scales and we find that the first modes all have obvious 1-year period oscillations, the first mode of the global ocean has 4-8 year period oscillations, and that of the Pacific has 2-6 year period oscillations. The spatial distribution of the linear rising trend of the global modified SSL in the upper 0-700 m layer is inhomogeneous with intense regional characteristics. The modified SSL linear trend indicates a zonal dipole in the tropical Pacific, rising in the west and descending in the east. In the North Atlantic, the modified SSL indicates a meridional dipole, rising in the latitude band of 20°N-40°N and 45°N-65.5°N and descending obviously in the latitude band of 40°N-45°N.
