The goal of this research is to investigate the ideas that functioned in shaping thought of Radif in Iranian Dastgahi music. In this regard by preparing the reasons, we pay attention to the function of education in co...The goal of this research is to investigate the ideas that functioned in shaping thought of Radif in Iranian Dastgahi music. In this regard by preparing the reasons, we pay attention to the function of education in codification of Radif. Although Iranian traditional music has long history but its codification to seven Dastgah-s and five Avaz-es in the format of Radif is attributed to Qajar Dynasty in the 19th century. In this transformation, Mirza Abdollah, Tar-Player of the Nasser al-Din Shah Period, has played an important role in final codification of Radif. Due to the truth that the past masters scrimped in music education, and Mirza Abdollah had encountered with problems to learn music, hence he has mostly cared about music education in adulthood, and it is probable that one of the reasons in collecting Gusheh-s （approximately a small piece of the Iranian Dastgahi music） and organizing them into coherent sets was making simplicity for the students to learn. Furthermore, masters who seriously and continuously have taught after Mirza Abdollah, left a narration （version） of Radif. On the other hand, definite patterns in placement of Gusheh-s and phrases of the Radif have been organized in a manner that makes educational function for it.展开更多
The etiology of inflammatory bowel disease(IBD) is not yet known,but many factors such as defects in the immune system,oxidative stress,microbial content in the gastrointestinal tract,nuclear factor(NF)-κB,nitric oxi...The etiology of inflammatory bowel disease(IBD) is not yet known,but many factors such as defects in the immune system,oxidative stress,microbial content in the gastrointestinal tract,nuclear factor(NF)-κB,nitric oxide(NO),cyclooxygenase-2(Cox-2),and leukotriene B4(LB4) are thought to play a role in its pathogenesis.In traditional Iranian medicine(TIM),several medicinal plants are thought to be effective for the treatment of IBD.In this study,information on all of these remedies were derived from all available old sources such as documents or notes and books and were added to the information derived from modern medical databases covering all in vitro,in vivo and clinical trials.For some of these plants,only one or two mechanisms of action have been found such as in Cassia fistula,Lepidium sativum,and Bunium persicum.However,for some plants various mechanisms of action are known.For example,Commiphora mukul is effective in IBD due to its immunomodulatory,antioxidant,and antibacterial properties and it decreases NF-κB,NO and Cox-2.Another herb,Plantago ovata,has immunomodulatory,antioxidant,anti-inflammatory and wound healing activities and decreases NO and LB4.Considering the mechanisms of action of these plants,the combination of some of them may be useful because of their many mechanisms of action such as Pistacia lentiscus,Bunium persicum,Solanum nigrum,Plantago ovata,Boswellia,Solanum nigrum,Plantago ovata and Commiphora mukul.For some of the herbal products used in TIM such as oleogum resin from Commiphora myrrha,seeds of Ocimum basilicum,seeds of Linum usitatissimum,gum resin of Dracaena cinnabari,seeds of Plantago major,seeds of Lallementia royleana,and seeds of Allium porrum,there is no or not enough studies to confirm their benefits in IBD.It is suggested that an evaluation of the effects of these plants on different aspects of IBD should be performed.展开更多
Data Envelopment Analysis （DEA） is a mathematical tech- nique to assess relative efficiencies of decision making units （DMUs）. The efficiency of 14 Iranian forest companies and forest management units was investig...Data Envelopment Analysis （DEA） is a mathematical tech- nique to assess relative efficiencies of decision making units （DMUs）. The efficiency of 14 Iranian forest companies and forest management units was investigated in 2010. Efficiency of the companies was esti- mated by using a traditional DEA model and a two-stage DEA model. Traditional DEA models consider all DMU activities as a black box and ignore the intermediate products, while two-stage models address inter- mediate processes. LINGO software was used for analysis. Overall pro- duction was divided into to processes for analyses by the two-stage model, timber harvest and marketing. Wilcoxon＇s signed-rank test was used to identify the differences of average efficiency in the harvesting and marketing sub-process. Weak performance in the harvesting sub-process was the cause of low efficiency in 2010. Companies such as Neka Chob and Kelardasht proved efficient at timber harvest, and Neka Chob forest company scored highest in overall efficiency. Finally, the reference units identified according to the results of two-stage DEA analysis.展开更多
Variation in the location of the South Asian High （SAH） in early boreal summer is strongly influenced by elevated surface heating from the Tibetan Plateau （TP） and the Iranian Plateau （IP）. Based on observationa...Variation in the location of the South Asian High （SAH） in early boreal summer is strongly influenced by elevated surface heating from the Tibetan Plateau （TP） and the Iranian Plateau （IP）. Based on observational and ERA-Interim data, diagnostic analyses reveal that the interannual northwestward-southeastwaxd （NW-SE） shift of the SAH in June is more closely correlated with the synergistic effect of concurrent surface thermal anomalies over the TP and IP than with each single surface thermal anomaly over either plateau from the preceding May. Concurrent surface thermal anomalies over these two plateaus in May are characterized by a negative correlation between sensible heat flux over most parts of the TP （TPSH） and IP （IPSH）. This anomaly pattern can persist till June and influences the NW-SE shift of the SAH in June through the release of latent heat （LH） over northeastern India. When the IPSH is stronger （weaker） and the TPSH is weaker （stronger） than normal in May, an anomalous cyclone （anticyclone） appears over northern India at 850 hPa, which is accompanied by the ascent （descent） of air and anomalous convergence （divergence） of moisture flux in May and June. Therefore, the LH release over northeastern India is strengthened （weakened） and the vertical gradient of apparent heat source is decreased （increased） in the upper troposphere, which is responsible for the northwestward （southeastward） shift of the SAH in June.展开更多
Background: The influence of Non-Alcoholic Fatty Liver Disease on the outcome of chronic hepatitis B disease, including viral, biochemical and histologic characteristics, in Iranian patients is not yet fully un- derst...Background: The influence of Non-Alcoholic Fatty Liver Disease on the outcome of chronic hepatitis B disease, including viral, biochemical and histologic characteristics, in Iranian patients is not yet fully un- derstood. Aim: To evaluate the effect of Non-Alcoholic Fatty Liver Disease (NAFLD) on long-term histology- cal, biochemical and viral outcome of chronic he- pa-tictis B in Iranian patients. Methods: We retro- spec-tively evaluated 94 “e Ag” negative chronic hepatitis B patients (with NAFLD: 44, without NAFLD: 50). Non-Alcoholic Fatty Liver Disease was diagnosed based on liver biopsy according to Kleiner classifica-tion. Liver biopsy was done for all patients. Serologi-cal and biochemical variables were evaluated with repeated measure analysis. Results: Non-Alcoholic Fat- ty Liver Disease (NAFLD) was present in 47% of the patients (44 out of 94 patients). In the NAFLD group, increase in AST, ALT, stage (P = 0.002), grade, and total score of liver biopsy were independently related to non-alcoholic fatty liver disease, while HBV-DNA viral load did not correlate with the presence of a fatty liver. Conclusion: Abnormalities of liver enzymes and liver histopathology are more prevalent in concurrent chronic hepatitis B and Non-Alcoholic Fatty Liver Disease (NAFLD).展开更多
AIM: To investigate the efficacy of Magliasa, a traditional Iranian formula, on experimental colitis. METHODS: After botanical authentication of herbal ingredients, formulation of Magliasa, quantitative determination ...AIM: To investigate the efficacy of Magliasa, a traditional Iranian formula, on experimental colitis. METHODS: After botanical authentication of herbal ingredients, formulation of Magliasa, quantitative determination of total glucosinolates and total phenolic content, and analysis of the thin layer chromatography profile were performed. Colitis was then induced in male rats by instillation of 2,4,6-trinitrobenzenesulfonic acid (TNBS) in all groups, aside from the Sham group.The experimental groups consisted of: the Sham group that received only normal saline; the Mag-50, Mag-100 and Mag-200 groups, which received 50, 100 and 200 mg/kg per day of Magliasa, respectively; the control group, which received vehicle water orally; the infliximab group, which received infliximab (5 mg/kg per day, subcutaneously); and the Dexa group, which received dexamethasone (1 mg/kg per day, orally). After completing the treatment period (2 wk), the rats were sacrificed, the colon was removed, its macroscopic and microscopic changes were recorded, and tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1b), total antioxidant capacity, myeloperoxidase (MPO), and lipid peroxidation (LPO) were assessed in colon homogenate.RESULTS: The mean value of total glucosinolates in one gram of Magliasa was 19 ± 1 μmol. The mean value of the total phenolic content was 293.8 ± 17.6 mg gallic acid equivalents per 100 gram of Magliasa. Macroscopic scores were significantly decreased in Mag-100 (1.80 ± 0.58, P = 0.019) and Mag-200 (1.20 ± 0.20, P = 0.001) compared to the control group (3.40 ± 0.24), although some inflammation and hyperemia were evident. Treatment of rats by dexamethasone (0.33 ± 0.21, P < 0.001) and infliximab (0.83 ± 0.31, P < 0.001) remarkably attenuated scores where mild hyperemia was observed macroscopically. In comparison to the control group (4.00 ± 0.32), only Mag-200 (1.60 ± 0.40) showed a significant decrease in colonic histopathological scores (P = 0.005). Minimal mucosal inflammation was observed in the Dexa group (0.67 ± 0.21, P < 0.001). The levels of TNF-α, IL-1b and MPO were significantly lower in all groups compared to the controls (P < 0.05). A significant decrease in LPO was seen in the Mag-200 (3.27 ± 0.77, P = 0.01) and Dexa (3.44 ± 0.22, P = 0.011) groups in comparison to the control group (6.43 ± 0.61). Only dexamethasone caused a significant increase in antioxidant power in comparison to the control group (346.73 ± 9.9 vs 228.33 ± 2.75, P < 0.001). Infliximab and different doses of Magliasa did not show any remarkable increase in antioxidant capacity (P > 0.05). The effect of Magliasa in all of mentioned parameters, except antioxidant capacity, was dose dependent.CONCLUSION: The effects of Magliasa in TNBS-induced colitis are encouraging and warrant clinical trials for further confirmation.展开更多
Predictive potential distribution modeling is of increasing importance in modern herpetological studies and determination of environmental and conservation priorities. In this article we provided results of analysis a...Predictive potential distribution modeling is of increasing importance in modern herpetological studies and determination of environmental and conservation priorities. In this article we provided results of analysis and forecasts of the potential distribution of smallscaled rock agama Paralaudakia microlepis （Blanford, 1874） using the distribution models through Maxent （www.cs.princeton.edu/- schapire / maxent）. We made an attempt for comparison of input of bioclimatic factors and characteristics of biotope distribution for three species of genus Paralaudalda. Constructed model identified dissemination of Paralaudakia microlepis enough performance （AUC = 0.972 with dispersion 0.003）. According to the map constructed, the most suitable habitats of smallscaled rock agama Paralaudakia microlepis are located in southern and eastern Iran, the west of central Pakistan and southeastern Afghanistan.展开更多
Terminalia chebula(family:Combretaceae)is widely used in the traditional medicine of India and Iran to treat diseases that include dementia,constipation,and diabetes.This tree is known in Iranian traditional medicine(...Terminalia chebula(family:Combretaceae)is widely used in the traditional medicine of India and Iran to treat diseases that include dementia,constipation,and diabetes.This tree is known in Iranian traditional medicine(ITM)as halileh or halilaj and the fruit is used to develop treatments.It is described in ITM as an astringent that has a"cold"and"dry"temperament.References to the medicinal properties of Terminalia chebula were collected from important ITM sources and from modern medical databases(Pub Med,Scirus,Science Direct,and Scopus).The medicinal properties described for thistree in ITM were compared with those reported in studies of modern phytotherapy.The results confirm that the tree referred to as halileh in traditional books is the Terminalia chebula used in present-day studies.Treatments that have not been evaluated in modern phytotherapy but have been traditionally treated with Terminalia chebula include fever,and psychological and psychiatric issues.This article confirms the medicinal uses of Terminalia chebula.展开更多
The Late Cretaceous Khabr-Marvast tectonized ophiolite is located in the middle part of the Nain-Baft ophiolite belt, at the south-western edge of the central Iranian microcontinent. Although all the volcanic rocks in...The Late Cretaceous Khabr-Marvast tectonized ophiolite is located in the middle part of the Nain-Baft ophiolite belt, at the south-western edge of the central Iranian microcontinent. Although all the volcanic rocks in the study area indicate subduction-related magmatism （e.g. high LILE （large ion lithophile elements） / HFSE （high field strenght elements） ratios and negative anomalies in Nb and Ta）, geological and geochemical data clearly distinguish two distinct groups of volcanic rocks in the tectonized association： （1） group 1 is comprised of hyaloclastic breccias, basaltic pillow lavas, and andesite sheet flows. These rocks represent the Nain-Baft oceanic crust; and （2） group 2 is alkaline lavas from the top section of the ophiolite suite. These lavas show shoshonite affinity, but do not support the propensity of ophiolite.展开更多
We used a goal programming technique to determine the optimal harvest volume for the Iranian Caspian forest. We collected data including volume, growth, wood price at forest roadside, and variable harvesting costs. Th...We used a goal programming technique to determine the optimal harvest volume for the Iranian Caspian forest. We collected data including volume, growth, wood price at forest roadside, and variable harvesting costs. The allometric method was used to quantify seques- trated carbon. Regression analysis was used to derive growth models. Expected mean price was estimated using wood price and variable harvesting costs. Questionnaire was used to determine the constraints and the equation coefficients of the goal programming model. The optimal volume was determined using the goal programming method according to multipurpose forest management. LINGO software was used for analysis. Results indicated that the optimum volumes of species were 250.25 m3.ha-1 for beech, 59 m3.ha-1 for hornbeam, 73 m3.ha-1 for oak, 41 m3.ha-1 for alder, and 32 m3.ha-1 for other species. The total optimum volume is 455.25 m3.ha-1.展开更多
Considering the fact that liver is one of the most important organs in our body,it deserves special attention and protection.Among various recommended supplements,complementary and alternative medicines particularly h...Considering the fact that liver is one of the most important organs in our body,it deserves special attention and protection.Among various recommended supplements,complementary and alternative medicines particularly herbal remedies have received much attention owing to their truly healing properties.This review profits from Iranian traditional medicine and presents advantageous herbal guide directions for liver protection.According to credible Iranian medical literature such as Al Qanun Fil Tibb.Al-Havi and Makhzan-al-Aadvia.a wide spectrum of plants have been found to be useful for cleansing and protecting the liver.Some herbs such as ghafes(Agrimonia eupatoria),kasni(Cichorium intybus),anar(Punica granatum),darchin(Cinnamomum zeylanicum),za'feran(Crocus sativus),gole-sorkh(Rosa damascena) and zereshk(Berberis vulgaris) appeared to get strong consideration and were well documented as outstanding liver tonics.We conducted a comprehensive review of available Iranian medical resources such as scientific information database and medical sciences databases which cover all in vitro and in vivo studies of medicinal plants as liver tonics and hepatoprotcctive candidates.Literature survey was accomplished using multiple databases including PubMed,ISI web of knowledge,and Google Scholar.展开更多
Constipation is one of the most common complaints of children and a common cause of referrals to pediatricians. Numerous reasons for this disease have been mentioned in the Iranian traditional medicine （ITM）. It is ...Constipation is one of the most common complaints of children and a common cause of referrals to pediatricians. Numerous reasons for this disease have been mentioned in the Iranian traditional medicine （ITM）. It is believed that this disorder is mostly due to the lack of consideration of the six essential principles （Setteh-ye-Zarurieah）, which are necessary to maintain health and prevent disease. In this descriptive study we collected and classified the concepts related to the topic by reviewing reliable ITM text books. Scientific databases were also searched for the most commonly used herbs in the treatment of constipation. The results showed that, from the perspective of ITM, the first step in treating constipation in children is making lifestyle changes. This includes giving appropriate training in the six essential principles, and making modification in existing habits where necessary. In the next steps, using some herbal remedies for topical or oral administration is recommended. On the other hand, a few clinical trials have been done concerning the effects of herbal medicines on pediatric constipation. Therefore, ITM＇s preventive and curative strategies can provide an efficient and cost-effective way to address constipation in children. This study can serve as a preface to performing clinical studies in this field.展开更多
Introduction: This study aimed to develop valid and reliable scale with the intention of measure Coping Self-efficacy (CSES) of Iranian type 2 diabetic patients. Patients and Methods: Validity and reliability of Irani...Introduction: This study aimed to develop valid and reliable scale with the intention of measure Coping Self-efficacy (CSES) of Iranian type 2 diabetic patients. Patients and Methods: Validity and reliability of Iranian version of Coping Self-efficacy Scale (CSES) were measured by a cross-sectional study. Content validity, reliability and cultural equivalency were appraised through qualitative and quantitative study on 260 participants who have type 2 diabetes. Results: Reliability and validity of the scale and its four subscales, such as “stop unpleasant emotions and thoughts” (a = 0.92) “used problem-focused coping” (a = 0.71), Self-efficacy on diabetes problem solving (a = 0.74) and “get support from friends and family” (a = 0.67) were approved explicitly by a psychometric analysis;these show that the scale was slightly valid and reliable on the study setting. An intraclass correlation coefficient was satisfactory (p < 0.001). Criterion validity between total scale and metabolic control Index (HbA1c) of type 2 diabetic patients was significant (p < 0.001) and showed indirect correlation with the domains of the scale. Conclusion: Study findings supported the reliability and validity of the Iranian version of new Coping Self-efficacy-24 for measuring Coping Selfefficacy among Iranian type 2 diabetic patients. Based on our finding, we would like to recommend appropriate interventions in the future.展开更多
The fact that distribution of body fat can have a major role in the development of metabolic derangement and cardiovascular diseases is supported by a considerable amount of evidence.Therefore it is no surprise that i...The fact that distribution of body fat can have a major role in the development of metabolic derangement and cardiovascular diseases is supported by a considerable amount of evidence.Therefore it is no surprise that increased of metabolic syndrome. New evidence describing adipose tissue as an advanced endocrine unit, capable of producing substances with remarkable physiologic impacts, has led to increased research interest in this field. While many fatty tissues are similar in composition, some of them, notably subcutaneous and visceral adipose tissues, possess special properties.展开更多
Based on Iran's sixth development plan,the country's oil and gas industry requires an investment of about$200 bn in the next five years to increase production.The Iranian government,to attract and motivate int...Based on Iran's sixth development plan,the country's oil and gas industry requires an investment of about$200 bn in the next five years to increase production.The Iranian government,to attract and motivate international oil company investment in their oil and gas fields,has presented a new type of risk service contract:the Iranian Petroleum Contract(IPC).This paper summarizes the features of the IPC and presents mathematical models of its fiscal regime for the benefit and guidance of both the National Iranian Oil Company(NIOC)and the contractors.Next,adopting bargaining game theory provides a mathematical model for reaching a win-win situation between the NIOC and the contractor.Finally,a numerical example is given and a sensitivity analysis performed to illustrate the implementation of the proposed models.The contractor and the NIOC may use these models when preparing their proposal and in the course of actual negotiations to calculate their internal rate of return,remuneration fee,and net present value for developing the fields at different conditions of their bargaining power,and derive a logical bargain to protect their best possible interests.展开更多
Introduction: Breast cancer is the most common cancer in the Iranian female population, and the incidence of the disease is rising. Early detection in association with staging or grading the tumor is the most effectiv...Introduction: Breast cancer is the most common cancer in the Iranian female population, and the incidence of the disease is rising. Early detection in association with staging or grading the tumor is the most effective method to increase survival rates. Studies have revealed that cortactin overexpression may play a role in the final stages of tumor progression and affects invasion and cellular motility. The aim of this study is to evaluate cortactin gene expression among Iranian female patients with breast cancer. Materials and Methods: Samples belonging to 70 breast cancer patients were randomly selected from the Imam Khomeini tumor bank. Normal and tumor tissues were prepared and stored at -80°C. Cortactin gene expression was evaluated by real-time PCR. Finally the data, along with demographic and clinical parameters, were analyzed using Prism 5.0 software, followed by t-test and ANOVA analysis. Results: Cortactin gene expression among tumor tissues increased 95.71% in comparison with normal tissues. A significant correlation between cortactin gene expression and lymph nodes’ involvement (P = 0.0077) and tumor stage (P = 0.0030) was observed. However, tumor grade (P = 0.8598), tumor size (P = 0.3058), and patient’s age (P = 0.4135) had no significant correlation with the gene’s expression level. Discussion: This study demonstrated that the cortactin gene’s overexpression in breast cancer may enhance lymph nodes’ involvement. This study also found that the gene’s expression was raised significantly in progressed stages of the cancer. Therefore, cortactin gene overexpression is an important factor indicating breast cells’ invasion. Conclusion: The cortactin gene’s expression level can be considered an accurate indicator for female breast cancer and also an appropriate biomarker for this cancer in clinical evaluations.展开更多
Objective: To assess the ameliorative properties of Iranian Trigonella foenum-graecum L.(T. foenum-graecum) seeds and Punica granatum L.(P. granatum) peel extracts against streptozotocin-induced diabetes in male guine...Objective: To assess the ameliorative properties of Iranian Trigonella foenum-graecum L.(T. foenum-graecum) seeds and Punica granatum L.(P. granatum) peel extracts against streptozotocin-induced diabetes in male guinea pigs.Methods: Sixty guinea pigs were divided into six groups(10 guinea pigs per group).Group 1 consisted of normal animals. Groups 2 and 3 were treated with Iranian T. foenum-graecum seeds and P. granatum peel extract alone, respectively. Group 4 was treated with streptozotocin only; whereas Groups 5 and 6 receiving streptozotocin were treated with Iranian T. foenum-graecum seeds and P. granatum peel extract, respectively.All animals were treated for 30 days, and the body weight, blood and liver biochemical parameters were measured.Results: Guinea pigs exposed to streptozotocin showed an alteration in body weight gain, fasting glucose level, kidney function parameters(blood urea nitrogen and creatinine) as well as decreased serum and hepatic total protein level. In addition, it increased the cholesterol and triglyceride level, while decreasing the hepatic glucose-6 phosphate dehydrogenase activity, glycogen, glutathione content and hepatic catalase activity. Oral treatment with T. foenum-graecum seeds and P. granatum peel extracts revealed significant protective properties with respect to body weight gain and other biochemical parameters studied.Conclusions: The Iranian T. foenum-graecum seeds and P. granatum peel extracts are significantly potent in ameliorating diabetic condition induced by streptozotocin and improving various biochemical parameters in serum and liver of guinea pigs.展开更多
The aim of this study was to develop and test a new basal area growth model in mixed species continuous cover forests in northern Iran.Weanalyzed 421 core samples from 6 main species in the forest area to develop our ...The aim of this study was to develop and test a new basal area growth model in mixed species continuous cover forests in northern Iran.Weanalyzed 421 core samples from 6 main species in the forest area to develop our growth model.In each plot,we measured variables such as total tree height(m),diameter at breast height(DBH)(cm)and basal area of larger trees as cumulative basal areas of trees(GCUM)ofDBH[5 cm.The empirical data were analyzed using regression analysis.There was a statistically significant nonlinear function between the annual basal area increment,as the dependent variable,and the basal area of the individual trees and competition as explanatory variables.Reference area from the largest trees,was circular plot with area of 0.1 ha.GCUM was estimated for trees of DBH>5 cm.Furthermore,we investigated the dependencies of diameter growth of different species on stand density at different levels of competition,and diameter development of individual trees through time.The results indicate that competition caused by larger neighborhood trees has a negative effect on growth.In addition,the maximum diameter increment is affected by competition level.Therefore,the maximum diameter increment of species occurs when the trees are about 35–40 cm in dense-forest(40 to 0 m^2 per ha)and when the trees are about 60 to 70 cm in very dense forest(60 to 0 m^2 per ha)which is more likely to Caspian natural forests with high level density due to uneven-aged composition of stands.展开更多
The eastern Iranian range,known as the Sistan suture zone in the past,has recently been identified as the Sistan orogen.This Paleogene orogeny is located between the Lut and Afghan microcontinents.The structural analy...The eastern Iranian range,known as the Sistan suture zone in the past,has recently been identified as the Sistan orogen.This Paleogene orogeny is located between the Lut and Afghan microcontinents.The structural analysis shows that most of the thrusts dip towards the NW so that the Permo-Triassic sediments and Jurassic micro-diorites of the Lut Block overthrusted over the younger rocks.Structural studies show that the tectonic vergence was from the NW to the SE of the Sechengi area in the NW part of Sistan orogen.We recognized three deformation phases in eastern Iran.The first N-S deformation event(D1)resulted in the formation of tight E-W folds(F1)and associated cleavages(S1).The second E-W deformation event(D2),which occurred in the late Paleogene led to the bending of older structures,including the axial plane of the first-generation folds giving them a new northwest direction(F2).Additionally,the ramp of the first-phase thrusts(striking E-W)was reactivated,acquiring a new NNW orientation and exhibiting SSE tectonic vergence.The third deformation event(D3)resulted in the formation of NNE and WNW conjugate faults in eastern Iran.Such consecutive deformation events perpendicular to each other are inconsistent with the models of simple linear orogen presented for eastern Iran(i.e.rifting of eastern Iran continental crust and subsequence linear collision)and seem more consistent with the buckling orogeny(Orocline).展开更多
文摘The goal of this research is to investigate the ideas that functioned in shaping thought of Radif in Iranian Dastgahi music. In this regard by preparing the reasons, we pay attention to the function of education in codification of Radif. Although Iranian traditional music has long history but its codification to seven Dastgah-s and five Avaz-es in the format of Radif is attributed to Qajar Dynasty in the 19th century. In this transformation, Mirza Abdollah, Tar-Player of the Nasser al-Din Shah Period, has played an important role in final codification of Radif. Due to the truth that the past masters scrimped in music education, and Mirza Abdollah had encountered with problems to learn music, hence he has mostly cared about music education in adulthood, and it is probable that one of the reasons in collecting Gusheh-s （approximately a small piece of the Iranian Dastgahi music） and organizing them into coherent sets was making simplicity for the students to learn. Furthermore, masters who seriously and continuously have taught after Mirza Abdollah, left a narration （version） of Radif. On the other hand, definite patterns in placement of Gusheh-s and phrases of the Radif have been organized in a manner that makes educational function for it.
文摘The etiology of inflammatory bowel disease(IBD) is not yet known,but many factors such as defects in the immune system,oxidative stress,microbial content in the gastrointestinal tract,nuclear factor(NF)-κB,nitric oxide(NO),cyclooxygenase-2(Cox-2),and leukotriene B4(LB4) are thought to play a role in its pathogenesis.In traditional Iranian medicine(TIM),several medicinal plants are thought to be effective for the treatment of IBD.In this study,information on all of these remedies were derived from all available old sources such as documents or notes and books and were added to the information derived from modern medical databases covering all in vitro,in vivo and clinical trials.For some of these plants,only one or two mechanisms of action have been found such as in Cassia fistula,Lepidium sativum,and Bunium persicum.However,for some plants various mechanisms of action are known.For example,Commiphora mukul is effective in IBD due to its immunomodulatory,antioxidant,and antibacterial properties and it decreases NF-κB,NO and Cox-2.Another herb,Plantago ovata,has immunomodulatory,antioxidant,anti-inflammatory and wound healing activities and decreases NO and LB4.Considering the mechanisms of action of these plants,the combination of some of them may be useful because of their many mechanisms of action such as Pistacia lentiscus,Bunium persicum,Solanum nigrum,Plantago ovata,Boswellia,Solanum nigrum,Plantago ovata and Commiphora mukul.For some of the herbal products used in TIM such as oleogum resin from Commiphora myrrha,seeds of Ocimum basilicum,seeds of Linum usitatissimum,gum resin of Dracaena cinnabari,seeds of Plantago major,seeds of Lallementia royleana,and seeds of Allium porrum,there is no or not enough studies to confirm their benefits in IBD.It is suggested that an evaluation of the effects of these plants on different aspects of IBD should be performed.
文摘Data Envelopment Analysis （DEA） is a mathematical tech- nique to assess relative efficiencies of decision making units （DMUs）. The efficiency of 14 Iranian forest companies and forest management units was investigated in 2010. Efficiency of the companies was esti- mated by using a traditional DEA model and a two-stage DEA model. Traditional DEA models consider all DMU activities as a black box and ignore the intermediate products, while two-stage models address inter- mediate processes. LINGO software was used for analysis. Overall pro- duction was divided into to processes for analyses by the two-stage model, timber harvest and marketing. Wilcoxon＇s signed-rank test was used to identify the differences of average efficiency in the harvesting and marketing sub-process. Weak performance in the harvesting sub-process was the cause of low efficiency in 2010. Companies such as Neka Chob and Kelardasht proved efficient at timber harvest, and Neka Chob forest company scored highest in overall efficiency. Finally, the reference units identified according to the results of two-stage DEA analysis.
基金supported by the National Natural Science Foundation of China (Grant Nos.91437219,41275075 and 41175005)the National Basic Research Program of China (Grant No.2013CB430203)
文摘Variation in the location of the South Asian High （SAH） in early boreal summer is strongly influenced by elevated surface heating from the Tibetan Plateau （TP） and the Iranian Plateau （IP）. Based on observational and ERA-Interim data, diagnostic analyses reveal that the interannual northwestward-southeastwaxd （NW-SE） shift of the SAH in June is more closely correlated with the synergistic effect of concurrent surface thermal anomalies over the TP and IP than with each single surface thermal anomaly over either plateau from the preceding May. Concurrent surface thermal anomalies over these two plateaus in May are characterized by a negative correlation between sensible heat flux over most parts of the TP （TPSH） and IP （IPSH）. This anomaly pattern can persist till June and influences the NW-SE shift of the SAH in June through the release of latent heat （LH） over northeastern India. When the IPSH is stronger （weaker） and the TPSH is weaker （stronger） than normal in May, an anomalous cyclone （anticyclone） appears over northern India at 850 hPa, which is accompanied by the ascent （descent） of air and anomalous convergence （divergence） of moisture flux in May and June. Therefore, the LH release over northeastern India is strengthened （weakened） and the vertical gradient of apparent heat source is decreased （increased） in the upper troposphere, which is responsible for the northwestward （southeastward） shift of the SAH in June.
文摘Background: The influence of Non-Alcoholic Fatty Liver Disease on the outcome of chronic hepatitis B disease, including viral, biochemical and histologic characteristics, in Iranian patients is not yet fully un- derstood. Aim: To evaluate the effect of Non-Alcoholic Fatty Liver Disease (NAFLD) on long-term histology- cal, biochemical and viral outcome of chronic he- pa-tictis B in Iranian patients. Methods: We retro- spec-tively evaluated 94 “e Ag” negative chronic hepatitis B patients (with NAFLD: 44, without NAFLD: 50). Non-Alcoholic Fatty Liver Disease was diagnosed based on liver biopsy according to Kleiner classifica-tion. Liver biopsy was done for all patients. Serologi-cal and biochemical variables were evaluated with repeated measure analysis. Results: Non-Alcoholic Fat- ty Liver Disease (NAFLD) was present in 47% of the patients (44 out of 94 patients). In the NAFLD group, increase in AST, ALT, stage (P = 0.002), grade, and total score of liver biopsy were independently related to non-alcoholic fatty liver disease, while HBV-DNA viral load did not correlate with the presence of a fatty liver. Conclusion: Abnormalities of liver enzymes and liver histopathology are more prevalent in concurrent chronic hepatitis B and Non-Alcoholic Fatty Liver Disease (NAFLD).
基金Supported by The Tehran University of Medical Sciences partly, as outcome of a PhD thesis and Iran National Science foundation
文摘AIM: To investigate the efficacy of Magliasa, a traditional Iranian formula, on experimental colitis. METHODS: After botanical authentication of herbal ingredients, formulation of Magliasa, quantitative determination of total glucosinolates and total phenolic content, and analysis of the thin layer chromatography profile were performed. Colitis was then induced in male rats by instillation of 2,4,6-trinitrobenzenesulfonic acid (TNBS) in all groups, aside from the Sham group.The experimental groups consisted of: the Sham group that received only normal saline; the Mag-50, Mag-100 and Mag-200 groups, which received 50, 100 and 200 mg/kg per day of Magliasa, respectively; the control group, which received vehicle water orally; the infliximab group, which received infliximab (5 mg/kg per day, subcutaneously); and the Dexa group, which received dexamethasone (1 mg/kg per day, orally). After completing the treatment period (2 wk), the rats were sacrificed, the colon was removed, its macroscopic and microscopic changes were recorded, and tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1b), total antioxidant capacity, myeloperoxidase (MPO), and lipid peroxidation (LPO) were assessed in colon homogenate.RESULTS: The mean value of total glucosinolates in one gram of Magliasa was 19 ± 1 μmol. The mean value of the total phenolic content was 293.8 ± 17.6 mg gallic acid equivalents per 100 gram of Magliasa. Macroscopic scores were significantly decreased in Mag-100 (1.80 ± 0.58, P = 0.019) and Mag-200 (1.20 ± 0.20, P = 0.001) compared to the control group (3.40 ± 0.24), although some inflammation and hyperemia were evident. Treatment of rats by dexamethasone (0.33 ± 0.21, P < 0.001) and infliximab (0.83 ± 0.31, P < 0.001) remarkably attenuated scores where mild hyperemia was observed macroscopically. In comparison to the control group (4.00 ± 0.32), only Mag-200 (1.60 ± 0.40) showed a significant decrease in colonic histopathological scores (P = 0.005). Minimal mucosal inflammation was observed in the Dexa group (0.67 ± 0.21, P < 0.001). The levels of TNF-α, IL-1b and MPO were significantly lower in all groups compared to the controls (P < 0.05). A significant decrease in LPO was seen in the Mag-200 (3.27 ± 0.77, P = 0.01) and Dexa (3.44 ± 0.22, P = 0.011) groups in comparison to the control group (6.43 ± 0.61). Only dexamethasone caused a significant increase in antioxidant power in comparison to the control group (346.73 ± 9.9 vs 228.33 ± 2.75, P < 0.001). Infliximab and different doses of Magliasa did not show any remarkable increase in antioxidant capacity (P > 0.05). The effect of Magliasa in all of mentioned parameters, except antioxidant capacity, was dose dependent.CONCLUSION: The effects of Magliasa in TNBS-induced colitis are encouraging and warrant clinical trials for further confirmation.
基金partially supported by grants from the Russian Foundation for Basic Research to NBA (Project 12-04-00057)the Scientific School Support Program (NSh- 2990.2014)
文摘Predictive potential distribution modeling is of increasing importance in modern herpetological studies and determination of environmental and conservation priorities. In this article we provided results of analysis and forecasts of the potential distribution of smallscaled rock agama Paralaudakia microlepis （Blanford, 1874） using the distribution models through Maxent （www.cs.princeton.edu/- schapire / maxent）. We made an attempt for comparison of input of bioclimatic factors and characteristics of biotope distribution for three species of genus Paralaudalda. Constructed model identified dissemination of Paralaudakia microlepis enough performance （AUC = 0.972 with dispersion 0.003）. According to the map constructed, the most suitable habitats of smallscaled rock agama Paralaudakia microlepis are located in southern and eastern Iran, the west of central Pakistan and southeastern Afghanistan.
文摘Terminalia chebula(family:Combretaceae)is widely used in the traditional medicine of India and Iran to treat diseases that include dementia,constipation,and diabetes.This tree is known in Iranian traditional medicine(ITM)as halileh or halilaj and the fruit is used to develop treatments.It is described in ITM as an astringent that has a"cold"and"dry"temperament.References to the medicinal properties of Terminalia chebula were collected from important ITM sources and from modern medical databases(Pub Med,Scirus,Science Direct,and Scopus).The medicinal properties described for thistree in ITM were compared with those reported in studies of modern phytotherapy.The results confirm that the tree referred to as halileh in traditional books is the Terminalia chebula used in present-day studies.Treatments that have not been evaluated in modern phytotherapy but have been traditionally treated with Terminalia chebula include fever,and psychological and psychiatric issues.This article confirms the medicinal uses of Terminalia chebula.
文摘The Late Cretaceous Khabr-Marvast tectonized ophiolite is located in the middle part of the Nain-Baft ophiolite belt, at the south-western edge of the central Iranian microcontinent. Although all the volcanic rocks in the study area indicate subduction-related magmatism （e.g. high LILE （large ion lithophile elements） / HFSE （high field strenght elements） ratios and negative anomalies in Nb and Ta）, geological and geochemical data clearly distinguish two distinct groups of volcanic rocks in the tectonized association： （1） group 1 is comprised of hyaloclastic breccias, basaltic pillow lavas, and andesite sheet flows. These rocks represent the Nain-Baft oceanic crust; and （2） group 2 is alkaline lavas from the top section of the ophiolite suite. These lavas show shoshonite affinity, but do not support the propensity of ophiolite.
文摘We used a goal programming technique to determine the optimal harvest volume for the Iranian Caspian forest. We collected data including volume, growth, wood price at forest roadside, and variable harvesting costs. The allometric method was used to quantify seques- trated carbon. Regression analysis was used to derive growth models. Expected mean price was estimated using wood price and variable harvesting costs. Questionnaire was used to determine the constraints and the equation coefficients of the goal programming model. The optimal volume was determined using the goal programming method according to multipurpose forest management. LINGO software was used for analysis. Results indicated that the optimum volumes of species were 250.25 m3.ha-1 for beech, 59 m3.ha-1 for hornbeam, 73 m3.ha-1 for oak, 41 m3.ha-1 for alder, and 32 m3.ha-1 for other species. The total optimum volume is 455.25 m3.ha-1.
基金Supported by Tehran University of Medical Sciences(Grant No.92-03-96-24313)
文摘Considering the fact that liver is one of the most important organs in our body,it deserves special attention and protection.Among various recommended supplements,complementary and alternative medicines particularly herbal remedies have received much attention owing to their truly healing properties.This review profits from Iranian traditional medicine and presents advantageous herbal guide directions for liver protection.According to credible Iranian medical literature such as Al Qanun Fil Tibb.Al-Havi and Makhzan-al-Aadvia.a wide spectrum of plants have been found to be useful for cleansing and protecting the liver.Some herbs such as ghafes(Agrimonia eupatoria),kasni(Cichorium intybus),anar(Punica granatum),darchin(Cinnamomum zeylanicum),za'feran(Crocus sativus),gole-sorkh(Rosa damascena) and zereshk(Berberis vulgaris) appeared to get strong consideration and were well documented as outstanding liver tonics.We conducted a comprehensive review of available Iranian medical resources such as scientific information database and medical sciences databases which cover all in vitro and in vivo studies of medicinal plants as liver tonics and hepatoprotcctive candidates.Literature survey was accomplished using multiple databases including PubMed,ISI web of knowledge,and Google Scholar.
文摘Constipation is one of the most common complaints of children and a common cause of referrals to pediatricians. Numerous reasons for this disease have been mentioned in the Iranian traditional medicine （ITM）. It is believed that this disorder is mostly due to the lack of consideration of the six essential principles （Setteh-ye-Zarurieah）, which are necessary to maintain health and prevent disease. In this descriptive study we collected and classified the concepts related to the topic by reviewing reliable ITM text books. Scientific databases were also searched for the most commonly used herbs in the treatment of constipation. The results showed that, from the perspective of ITM, the first step in treating constipation in children is making lifestyle changes. This includes giving appropriate training in the six essential principles, and making modification in existing habits where necessary. In the next steps, using some herbal remedies for topical or oral administration is recommended. On the other hand, a few clinical trials have been done concerning the effects of herbal medicines on pediatric constipation. Therefore, ITM＇s preventive and curative strategies can provide an efficient and cost-effective way to address constipation in children. This study can serve as a preface to performing clinical studies in this field.
文摘Introduction: This study aimed to develop valid and reliable scale with the intention of measure Coping Self-efficacy (CSES) of Iranian type 2 diabetic patients. Patients and Methods: Validity and reliability of Iranian version of Coping Self-efficacy Scale (CSES) were measured by a cross-sectional study. Content validity, reliability and cultural equivalency were appraised through qualitative and quantitative study on 260 participants who have type 2 diabetes. Results: Reliability and validity of the scale and its four subscales, such as “stop unpleasant emotions and thoughts” (a = 0.92) “used problem-focused coping” (a = 0.71), Self-efficacy on diabetes problem solving (a = 0.74) and “get support from friends and family” (a = 0.67) were approved explicitly by a psychometric analysis;these show that the scale was slightly valid and reliable on the study setting. An intraclass correlation coefficient was satisfactory (p < 0.001). Criterion validity between total scale and metabolic control Index (HbA1c) of type 2 diabetic patients was significant (p < 0.001) and showed indirect correlation with the domains of the scale. Conclusion: Study findings supported the reliability and validity of the Iranian version of new Coping Self-efficacy-24 for measuring Coping Selfefficacy among Iranian type 2 diabetic patients. Based on our finding, we would like to recommend appropriate interventions in the future.
文摘The fact that distribution of body fat can have a major role in the development of metabolic derangement and cardiovascular diseases is supported by a considerable amount of evidence.Therefore it is no surprise that increased of metabolic syndrome. New evidence describing adipose tissue as an advanced endocrine unit, capable of producing substances with remarkable physiologic impacts, has led to increased research interest in this field. While many fatty tissues are similar in composition, some of them, notably subcutaneous and visceral adipose tissues, possess special properties.
文摘Based on Iran's sixth development plan,the country's oil and gas industry requires an investment of about$200 bn in the next five years to increase production.The Iranian government,to attract and motivate international oil company investment in their oil and gas fields,has presented a new type of risk service contract:the Iranian Petroleum Contract(IPC).This paper summarizes the features of the IPC and presents mathematical models of its fiscal regime for the benefit and guidance of both the National Iranian Oil Company(NIOC)and the contractors.Next,adopting bargaining game theory provides a mathematical model for reaching a win-win situation between the NIOC and the contractor.Finally,a numerical example is given and a sensitivity analysis performed to illustrate the implementation of the proposed models.The contractor and the NIOC may use these models when preparing their proposal and in the course of actual negotiations to calculate their internal rate of return,remuneration fee,and net present value for developing the fields at different conditions of their bargaining power,and derive a logical bargain to protect their best possible interests.
文摘Introduction: Breast cancer is the most common cancer in the Iranian female population, and the incidence of the disease is rising. Early detection in association with staging or grading the tumor is the most effective method to increase survival rates. Studies have revealed that cortactin overexpression may play a role in the final stages of tumor progression and affects invasion and cellular motility. The aim of this study is to evaluate cortactin gene expression among Iranian female patients with breast cancer. Materials and Methods: Samples belonging to 70 breast cancer patients were randomly selected from the Imam Khomeini tumor bank. Normal and tumor tissues were prepared and stored at -80°C. Cortactin gene expression was evaluated by real-time PCR. Finally the data, along with demographic and clinical parameters, were analyzed using Prism 5.0 software, followed by t-test and ANOVA analysis. Results: Cortactin gene expression among tumor tissues increased 95.71% in comparison with normal tissues. A significant correlation between cortactin gene expression and lymph nodes’ involvement (P = 0.0077) and tumor stage (P = 0.0030) was observed. However, tumor grade (P = 0.8598), tumor size (P = 0.3058), and patient’s age (P = 0.4135) had no significant correlation with the gene’s expression level. Discussion: This study demonstrated that the cortactin gene’s overexpression in breast cancer may enhance lymph nodes’ involvement. This study also found that the gene’s expression was raised significantly in progressed stages of the cancer. Therefore, cortactin gene overexpression is an important factor indicating breast cells’ invasion. Conclusion: The cortactin gene’s expression level can be considered an accurate indicator for female breast cancer and also an appropriate biomarker for this cancer in clinical evaluations.
文摘Objective: To assess the ameliorative properties of Iranian Trigonella foenum-graecum L.(T. foenum-graecum) seeds and Punica granatum L.(P. granatum) peel extracts against streptozotocin-induced diabetes in male guinea pigs.Methods: Sixty guinea pigs were divided into six groups(10 guinea pigs per group).Group 1 consisted of normal animals. Groups 2 and 3 were treated with Iranian T. foenum-graecum seeds and P. granatum peel extract alone, respectively. Group 4 was treated with streptozotocin only; whereas Groups 5 and 6 receiving streptozotocin were treated with Iranian T. foenum-graecum seeds and P. granatum peel extract, respectively.All animals were treated for 30 days, and the body weight, blood and liver biochemical parameters were measured.Results: Guinea pigs exposed to streptozotocin showed an alteration in body weight gain, fasting glucose level, kidney function parameters(blood urea nitrogen and creatinine) as well as decreased serum and hepatic total protein level. In addition, it increased the cholesterol and triglyceride level, while decreasing the hepatic glucose-6 phosphate dehydrogenase activity, glycogen, glutathione content and hepatic catalase activity. Oral treatment with T. foenum-graecum seeds and P. granatum peel extracts revealed significant protective properties with respect to body weight gain and other biochemical parameters studied.Conclusions: The Iranian T. foenum-graecum seeds and P. granatum peel extracts are significantly potent in ameliorating diabetic condition induced by streptozotocin and improving various biochemical parameters in serum and liver of guinea pigs.
基金Ministry of Science,Research and Technology of Iran for the scholarship to Nishtman Hatami to take a short time study in Sweden
文摘The aim of this study was to develop and test a new basal area growth model in mixed species continuous cover forests in northern Iran.Weanalyzed 421 core samples from 6 main species in the forest area to develop our growth model.In each plot,we measured variables such as total tree height(m),diameter at breast height(DBH)(cm)and basal area of larger trees as cumulative basal areas of trees(GCUM)ofDBH[5 cm.The empirical data were analyzed using regression analysis.There was a statistically significant nonlinear function between the annual basal area increment,as the dependent variable,and the basal area of the individual trees and competition as explanatory variables.Reference area from the largest trees,was circular plot with area of 0.1 ha.GCUM was estimated for trees of DBH>5 cm.Furthermore,we investigated the dependencies of diameter growth of different species on stand density at different levels of competition,and diameter development of individual trees through time.The results indicate that competition caused by larger neighborhood trees has a negative effect on growth.In addition,the maximum diameter increment is affected by competition level.Therefore,the maximum diameter increment of species occurs when the trees are about 35–40 cm in dense-forest(40 to 0 m^2 per ha)and when the trees are about 60 to 70 cm in very dense forest(60 to 0 m^2 per ha)which is more likely to Caspian natural forests with high level density due to uneven-aged composition of stands.
基金financially and technically supported by the University of Birjand under Project Number 7912.
文摘The eastern Iranian range,known as the Sistan suture zone in the past,has recently been identified as the Sistan orogen.This Paleogene orogeny is located between the Lut and Afghan microcontinents.The structural analysis shows that most of the thrusts dip towards the NW so that the Permo-Triassic sediments and Jurassic micro-diorites of the Lut Block overthrusted over the younger rocks.Structural studies show that the tectonic vergence was from the NW to the SE of the Sechengi area in the NW part of Sistan orogen.We recognized three deformation phases in eastern Iran.The first N-S deformation event(D1)resulted in the formation of tight E-W folds(F1)and associated cleavages(S1).The second E-W deformation event(D2),which occurred in the late Paleogene led to the bending of older structures,including the axial plane of the first-generation folds giving them a new northwest direction(F2).Additionally,the ramp of the first-phase thrusts(striking E-W)was reactivated,acquiring a new NNW orientation and exhibiting SSE tectonic vergence.The third deformation event(D3)resulted in the formation of NNE and WNW conjugate faults in eastern Iran.Such consecutive deformation events perpendicular to each other are inconsistent with the models of simple linear orogen presented for eastern Iran(i.e.rifting of eastern Iran continental crust and subsequence linear collision)and seem more consistent with the buckling orogeny(Orocline).
