The Arab Spring is supposed to be the Arab world’s great changes and turmoil,but Iran has repeatedly become the focus in the following changes.Whether it is in the Syrian civil war,or strikes against ISIS,or the Qata...The Arab Spring is supposed to be the Arab world’s great changes and turmoil,but Iran has repeatedly become the focus in the following changes.Whether it is in the Syrian civil war,or strikes against ISIS,or the Qatar crisis,Iran repeatedly appeared.There are different attitudes towards Iran’s behavior.The Trump administration holds the opinion that Iran is展开更多
Background:Bordetella pertussis,the causative agent of whooping cough,is a significant contributor to recurrent persistent cough across all age groups,including vaccinated individuals.This seroepidemiological study ai...Background:Bordetella pertussis,the causative agent of whooping cough,is a significant contributor to recurrent persistent cough across all age groups,including vaccinated individuals.This seroepidemiological study aims to address the gap in understanding pertussis incidence by investigating its occurrence in individuals with persistent cough and describing the characteristics of affected patients admitted to clinical centers in Jahrom,Southwest Iran.Methods:This cross-sectional study enrolled 110 patients with a cough persisting for at least 2 weeks,admitted to clinical centers in Jahrom,Iran.Blood samples were collected at baseline and on day 21 of follow-up.Serum samples were analyzed for anti-pertussis toxin immunoglobulin G(anti-PT-IgG)levels using an enzyme-linked immunosorbent assay.Demographic factors,including age,gender,occupation,area of residence,and family size,were also evaluated.Results:Among the 110 participants,77(70%)were female,and seven patients(6.4%)tested seropositive for anti-PT-IgG.No significant associations were observed between pertussis incidence and the analyzed variables,including age,gender,occupation,area of residence(urban vs.rural),and family size(p>0.05).These findings underscore the importance of enhancing vaccination coverage to reduce the prevalence of B.pertussis in the community.Conclusion:This study highlights the occurrence of pertussis in individuals presenting solely with a persistent cough,absent of classic symptoms.The findings emphasize the need for healthcare providers to conduct detailed assessments and utilize rapid diagnostic methods for timely detection.This is particularly crucial in regions with high vaccination rates but limited awareness of pertussis recurrence.展开更多
The Mahabad rhyolitic complex,mostly composed of rhyolite but also including granite and granodiorite,is exposed in NW Iran as a part of the Central Iran Block.Porphyritic,hyalo-porphyritic and spheroidal are the main...The Mahabad rhyolitic complex,mostly composed of rhyolite but also including granite and granodiorite,is exposed in NW Iran as a part of the Central Iran Block.Porphyritic,hyalo-porphyritic and spheroidal are the main textures of the studied samples of rhyolite.U-Pb zircon chronology on three samples of Mahabad rhyolitic complex yielded Cambrian to Ediacaran ages of 537.6±6.6 Ma,547.4±6.5 Ma and 556.2±7.1 Ma.Based on geochemical analyses,the original magma was high potassium calc-alkaline to shoshonitic.The rocks are enriched in LREEs relative to HREEs.Trace element patterns of Mahabad rhyolite normalized to chondrites show negative anomalies of high-fi eld-strength elements(Ti,Nb,Ta,Hf,Yb,Y and Zr)and high LREEs and large ion lithophile element contents(Rb,K,Th and Ba).^(208)Pb/^(204) Pb(36.7219–39.0367),^(207) Pb/^(204) Pb(15.4963–15.7669)and ^(206) Pb/^(204) Pb(16.9405–19.9567)ratios indicate an EM-II enriched mantle source for the rhyolite magma.Large variation ofεHf(t)from−5.2 to+4.5 points to a mantle source with crustal material contribution in the magma genesis.The rhyolitic magma erupted in an active continental margin.The formation of calc-alkaline high potassium magma was probably related to metasomatism of the mantle because of the north to south subduction of Proto-Tethys oceanic crust beneath the northern margin of Gondwana continental crust.展开更多
Background Mental disorders rank among the leading contributors to the global disease burden, with depressive disorders being among the most prevalent.Aims The objective of this study is to examine the prevalence, inc...Background Mental disorders rank among the leading contributors to the global disease burden, with depressive disorders being among the most prevalent.Aims The objective of this study is to examine the prevalence, incidence and years lived with disability (YLDs) associated with depressive disorders, particularly major depressive disorder and dysthymia, in Iran from 1990 to 2021. To achieve this, the research focused on analysing these metrics across various dimensions, including temporal trends, sex differences, age categories and subnational regions.Methods The data used in this study are sourced directly from the Institute for Health Metrics and Evaluation, ensuring that the information is both authoritative and reliable. All-age count estimates and age-standardised rates (per 100 000) were calculated for prevalence, incidence and YLDs. The disease burden indicators were analysed for the period spanning from 1990 to 2021, stratified by sex, age and location. The percentage change between 1990 and 2021 was also documented. The 95% uncertainty interval (UI) was reported for each of the reported estimates.Results The prevalence of depressive disorders in Iran demonstrated a notable upward trend from 1990 to 2021, with the rate of growth being particularly pronounced within the country. The age-standardised prevalence rate per 100 000 individuals for depressive disorders in Iran was 5609 (95% UI 4810 to 6488). By 2021, the number of depression cases in Iran reached 5.2 million, which is approximately 2.37 times the figure reported in 1990. The prevalence of depressive disorders was notably higher among females compared with males. The age-standardised prevalence rate per 100 000 individuals for males was 4184 (95% UI 3545 to 4929). For females, this figure was significantly greater, reaching 7077 (95% UI 6115 to 8172). Out of the total reported cases of depressive disorders in Iran, 3.2 million were observed in females, while males accounted for 2 million cases.Conclusions The findings highlighted the considerable impact of depressive disorders in Iran, both nationally and regionally, while also revealing variations across sex and age groups. Given the shifts in the demographic structure and the growing burden of these disorders, it is essential to prioritise screening initiatives, education programmes and strategies aimed at enhancing mental health awareness and ensuring improved access to mental health services in health policy planning.展开更多
AIM:To examine whether rs2472493 and rs248032 in the ABCA1 gene,rs3785176 in the PMM2 gene,and rs11827818 in the ARHGEF12 gene contribute to primary open angle glaucoma(POAG)in an Iranian population.METHODS:Totally 82...AIM:To examine whether rs2472493 and rs248032 in the ABCA1 gene,rs3785176 in the PMM2 gene,and rs11827818 in the ARHGEF12 gene contribute to primary open angle glaucoma(POAG)in an Iranian population.METHODS:Totally 82 POAG patients and 172 healthy controls were enrolled.The selected gene polymorphisms were analyzed using TaqMan SNP Genotyping Assay using deoxyribonucleic acid(DNA)extracted from blood samples.Allelic and genotypic frequencies were evaluated using the Chi-square test.The association between the genotypes of single nucleotide polymorphisms(SNPs)and POAG was assessed using multiple logistic regression models.The linkage disequilibrium and haplotype block structure were assessed using the Haploview 4.2 software.RESULTS:The results showed a significant association between allele frequencies of rs2472493 in the ABCA1 gene locus and POAG[odds ratio(OR)=1.58,95%confidence intervals(CI)=1.04-2.39,P=0.031].The rs3785176 in the PMM2 gene was also associated with POAG in additive and over dominant genotypes.Moreover,haplotype analysis showed a significant association of two estimated haplotypes of rs2472493/rs2487032 with POAG.The AA haplotype showed a reduction in POAG risk(OR=0.41,95%CI=0.202-0.834,P=0.012),while the GG haplotype was associated with the disease.In addition,this study could not discover any association between genotype and allele frequency of rs248032 in the ABCA1 gene,and rs11827818 in ARHGEF12 gene and POAG.CONCLUSION:rs2472493 in the ABCA1 gene can be considered a genetic susceptibility locus for POAG.The haplotype constructed with ABCA1 gene SNPs(rs2472493/rs2487032)is associated with POAG.展开更多
The subfamily Panchaetothripinae Bagnall is one of the 4 subfamilies in the family Thripidae. This subfamily includes 6 species in 5 genera in Iran. In this paper, the monobasic genus Selenothrips Kamy is recorded in ...The subfamily Panchaetothripinae Bagnall is one of the 4 subfamilies in the family Thripidae. This subfamily includes 6 species in 5 genera in Iran. In this paper, the monobasic genus Selenothrips Kamy is recorded in Iran for the first time. A key is provided for identifying these 6 genera with comments on each genus and its species. The geographical distribution is provided for 7 species occurring in Iran.展开更多
文摘The Arab Spring is supposed to be the Arab world’s great changes and turmoil,but Iran has repeatedly become the focus in the following changes.Whether it is in the Syrian civil war,or strikes against ISIS,or the Qatar crisis,Iran repeatedly appeared.There are different attitudes towards Iran’s behavior.The Trump administration holds the opinion that Iran is
文摘Background:Bordetella pertussis,the causative agent of whooping cough,is a significant contributor to recurrent persistent cough across all age groups,including vaccinated individuals.This seroepidemiological study aims to address the gap in understanding pertussis incidence by investigating its occurrence in individuals with persistent cough and describing the characteristics of affected patients admitted to clinical centers in Jahrom,Southwest Iran.Methods:This cross-sectional study enrolled 110 patients with a cough persisting for at least 2 weeks,admitted to clinical centers in Jahrom,Iran.Blood samples were collected at baseline and on day 21 of follow-up.Serum samples were analyzed for anti-pertussis toxin immunoglobulin G(anti-PT-IgG)levels using an enzyme-linked immunosorbent assay.Demographic factors,including age,gender,occupation,area of residence,and family size,were also evaluated.Results:Among the 110 participants,77(70%)were female,and seven patients(6.4%)tested seropositive for anti-PT-IgG.No significant associations were observed between pertussis incidence and the analyzed variables,including age,gender,occupation,area of residence(urban vs.rural),and family size(p>0.05).These findings underscore the importance of enhancing vaccination coverage to reduce the prevalence of B.pertussis in the community.Conclusion:This study highlights the occurrence of pertussis in individuals presenting solely with a persistent cough,absent of classic symptoms.The findings emphasize the need for healthcare providers to conduct detailed assessments and utilize rapid diagnostic methods for timely detection.This is particularly crucial in regions with high vaccination rates but limited awareness of pertussis recurrence.
文摘The Mahabad rhyolitic complex,mostly composed of rhyolite but also including granite and granodiorite,is exposed in NW Iran as a part of the Central Iran Block.Porphyritic,hyalo-porphyritic and spheroidal are the main textures of the studied samples of rhyolite.U-Pb zircon chronology on three samples of Mahabad rhyolitic complex yielded Cambrian to Ediacaran ages of 537.6±6.6 Ma,547.4±6.5 Ma and 556.2±7.1 Ma.Based on geochemical analyses,the original magma was high potassium calc-alkaline to shoshonitic.The rocks are enriched in LREEs relative to HREEs.Trace element patterns of Mahabad rhyolite normalized to chondrites show negative anomalies of high-fi eld-strength elements(Ti,Nb,Ta,Hf,Yb,Y and Zr)and high LREEs and large ion lithophile element contents(Rb,K,Th and Ba).^(208)Pb/^(204) Pb(36.7219–39.0367),^(207) Pb/^(204) Pb(15.4963–15.7669)and ^(206) Pb/^(204) Pb(16.9405–19.9567)ratios indicate an EM-II enriched mantle source for the rhyolite magma.Large variation ofεHf(t)from−5.2 to+4.5 points to a mantle source with crustal material contribution in the magma genesis.The rhyolitic magma erupted in an active continental margin.The formation of calc-alkaline high potassium magma was probably related to metasomatism of the mantle because of the north to south subduction of Proto-Tethys oceanic crust beneath the northern margin of Gondwana continental crust.
文摘Background Mental disorders rank among the leading contributors to the global disease burden, with depressive disorders being among the most prevalent.Aims The objective of this study is to examine the prevalence, incidence and years lived with disability (YLDs) associated with depressive disorders, particularly major depressive disorder and dysthymia, in Iran from 1990 to 2021. To achieve this, the research focused on analysing these metrics across various dimensions, including temporal trends, sex differences, age categories and subnational regions.Methods The data used in this study are sourced directly from the Institute for Health Metrics and Evaluation, ensuring that the information is both authoritative and reliable. All-age count estimates and age-standardised rates (per 100 000) were calculated for prevalence, incidence and YLDs. The disease burden indicators were analysed for the period spanning from 1990 to 2021, stratified by sex, age and location. The percentage change between 1990 and 2021 was also documented. The 95% uncertainty interval (UI) was reported for each of the reported estimates.Results The prevalence of depressive disorders in Iran demonstrated a notable upward trend from 1990 to 2021, with the rate of growth being particularly pronounced within the country. The age-standardised prevalence rate per 100 000 individuals for depressive disorders in Iran was 5609 (95% UI 4810 to 6488). By 2021, the number of depression cases in Iran reached 5.2 million, which is approximately 2.37 times the figure reported in 1990. The prevalence of depressive disorders was notably higher among females compared with males. The age-standardised prevalence rate per 100 000 individuals for males was 4184 (95% UI 3545 to 4929). For females, this figure was significantly greater, reaching 7077 (95% UI 6115 to 8172). Out of the total reported cases of depressive disorders in Iran, 3.2 million were observed in females, while males accounted for 2 million cases.Conclusions The findings highlighted the considerable impact of depressive disorders in Iran, both nationally and regionally, while also revealing variations across sex and age groups. Given the shifts in the demographic structure and the growing burden of these disorders, it is essential to prioritise screening initiatives, education programmes and strategies aimed at enhancing mental health awareness and ensuring improved access to mental health services in health policy planning.
基金Supported by the Noor Ophthalmology Research Center and Shahroud University of Medical Sciences(No.9449)Shahroud University of Medical Sciences(No.9449)Shahroud Eye Cohort Study is supported by the Noor Ophthalmology Research Center and Shahroud University of Medical Sciences(No.8737).
文摘AIM:To examine whether rs2472493 and rs248032 in the ABCA1 gene,rs3785176 in the PMM2 gene,and rs11827818 in the ARHGEF12 gene contribute to primary open angle glaucoma(POAG)in an Iranian population.METHODS:Totally 82 POAG patients and 172 healthy controls were enrolled.The selected gene polymorphisms were analyzed using TaqMan SNP Genotyping Assay using deoxyribonucleic acid(DNA)extracted from blood samples.Allelic and genotypic frequencies were evaluated using the Chi-square test.The association between the genotypes of single nucleotide polymorphisms(SNPs)and POAG was assessed using multiple logistic regression models.The linkage disequilibrium and haplotype block structure were assessed using the Haploview 4.2 software.RESULTS:The results showed a significant association between allele frequencies of rs2472493 in the ABCA1 gene locus and POAG[odds ratio(OR)=1.58,95%confidence intervals(CI)=1.04-2.39,P=0.031].The rs3785176 in the PMM2 gene was also associated with POAG in additive and over dominant genotypes.Moreover,haplotype analysis showed a significant association of two estimated haplotypes of rs2472493/rs2487032 with POAG.The AA haplotype showed a reduction in POAG risk(OR=0.41,95%CI=0.202-0.834,P=0.012),while the GG haplotype was associated with the disease.In addition,this study could not discover any association between genotype and allele frequency of rs248032 in the ABCA1 gene,and rs11827818 in ARHGEF12 gene and POAG.CONCLUSION:rs2472493 in the ABCA1 gene can be considered a genetic susceptibility locus for POAG.The haplotype constructed with ABCA1 gene SNPs(rs2472493/rs2487032)is associated with POAG.
文摘The subfamily Panchaetothripinae Bagnall is one of the 4 subfamilies in the family Thripidae. This subfamily includes 6 species in 5 genera in Iran. In this paper, the monobasic genus Selenothrips Kamy is recorded in Iran for the first time. A key is provided for identifying these 6 genera with comments on each genus and its species. The geographical distribution is provided for 7 species occurring in Iran.
