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Effectiveness of lorazepam-assisted interviews in an adolescent with dissociative amnesia A case report
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作者 Yuna Seo Mi-Hee Shin +1 位作者 Sung-Gon Kim Ji-Hoon Kim 《Neural Regeneration Research》 SCIE CAS CSCD 2013年第2期186-190,共5页
To facilitate gathering information during a psychiatric interview, some psychiatrists advocate augmenting the interview using drugs. Rather than barbiturates, benzodiazepines have been used for drug-assisted intervie... To facilitate gathering information during a psychiatric interview, some psychiatrists advocate augmenting the interview using drugs. Rather than barbiturates, benzodiazepines have been used for drug-assisted interviews. Dissociative amnesia is one of the indications for these interviews. Herein, we present the case of a 15-year-old female who was diagnosed as having dissociative amnesia because of conflicts with her friends. She was administered a Iorazepam-assisted interview to aid recovery of her memories. In this case, a small dose of Iorazepam was sufficient to recover her memories without any adverse effects. 展开更多
关键词 neural regeneration clinical practice dissociative amnesia dissociative disorder dissociation drug-assisted interview amobarbital iorazepam BENZODIAZEPINE ADOLESCENT memory loss emotional distress DISTRESS grant-supported paper NEUROREGENERATION
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HPLC法测定劳拉西泮片有关物质的含量 被引量:3
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作者 孙爱华 胡文辉 《安徽医药》 CAS 2016年第5期866-869,共4页
目的建立劳拉西泮片的含量及有关物质的HPLC方法。方法以十八烷基硅烷键合硅胶作为填充剂的ZORBAX SB-C18柱(250 mm×4.6 mm,5μm)为色谱柱,流动相:0.05 mol·L^(-1)的磷酸二氢铵(含0.5%的三乙胺,用磷酸调p H至2.5)∶甲醇∶乙腈... 目的建立劳拉西泮片的含量及有关物质的HPLC方法。方法以十八烷基硅烷键合硅胶作为填充剂的ZORBAX SB-C18柱(250 mm×4.6 mm,5μm)为色谱柱,流动相:0.05 mol·L^(-1)的磷酸二氢铵(含0.5%的三乙胺,用磷酸调p H至2.5)∶甲醇∶乙腈=35∶35∶30;流速:1.0 m L·min^(-1);检测波长:235 nm;进样量:10μL;柱温:30℃。结果劳拉西泮峰及各杂质峰均能良好分离。杂质A浓度与峰面积在1.5μg·L^(-1)~8.048 mg·L^(-1)内线性关系良好。杂质B浓度与峰面积在15.0μg·L^(-1)~8.224 mg·L~(^(-1))内线性关系良好。杂质C浓度与峰面积在1.7μg·L^(-1)~8.144 mg·L^(-1)内线性关系良好;杂质D浓度与峰面积在2.5μg·L^(-1)~8.032 mg·L^(-1)内线性关系良好;杂质E浓度与峰面积在3.0μg·L^(-1)~8.032 mg·L^(-1)内线性关系良好。测定样品含量平均值为97.9%,有关物质均符合要求。结论该方法快速、简单,稳定,重现性好,可作为劳拉西泮片的含量及有关物质的检测方法。 展开更多
关键词 劳拉西泮 色谱法 高压液相
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