CD4^(+)T-helper 1 cell(Th1)function is closely regulated by an intrinsic developmental program in which activation/induction and proinflammatory interferon(IFN)-γ secretion are followed by a deactivation/contraction ...CD4^(+)T-helper 1 cell(Th1)function is closely regulated by an intrinsic developmental program in which activation/induction and proinflammatory interferon(IFN)-γ secretion are followed by a deactivation/contraction period characterized by a switch into cosecretion of immunoregulatory interleukin(IL)-10.展开更多
文摘CD4^(+)T-helper 1 cell(Th1)function is closely regulated by an intrinsic developmental program in which activation/induction and proinflammatory interferon(IFN)-γ secretion are followed by a deactivation/contraction period characterized by a switch into cosecretion of immunoregulatory interleukin(IL)-10.