Objective: To explore the clinical effectiveness of combined use of intravenous pain pump with Parecoxib injection in alleviating pain in patients during the early postoperative period after thoracoscopic surgery. Met...Objective: To explore the clinical effectiveness of combined use of intravenous pain pump with Parecoxib injection in alleviating pain in patients during the early postoperative period after thoracoscopic surgery. Methods: Eighty patients who underwent thoracoscopic surgery in a tertiary hospital were selected as the study subjects and randomly divided into two groups, with 40 patients in each group. The control group received routine postoperative treatment with intravenous pain pump, while the experimental group received Parecoxib in addition to the standard postoperative pain pump treatment. Visual Analog Scale (VAS) pain scores were used to evaluate postoperative pain relief in both groups, along with adverse reactions, postoperative complications, and patient satisfaction with pain relief. Results: Patients who received Parecoxib injection in addition to the routine use of intravenous pain pump had VAS pain scores lower than 3 points at 6 h, 12 h, 24 h, and 36 h postoperatively compared to those in the control group. The incidence of postoperative lung collapse, pleural effusion, and pulmonary infections was also significantly lower in the experimental group. The differences between the two groups were statistically significant (P Conclusion: Early combined use of Parecoxib injection in the early postoperative period after thoracoscopic surgery has shown good clinical efficacy. It can reduce the level of pain in patients, promote effective coughing and expectoration, facilitate early mobilization of patients, improve patient compliance, reduce complications, shorten hospital stay, and expedite patient recovery. Therefore, it is worth promoting the widespread clinical application of Parecoxib injection in this setting.展开更多
Objective: to explore the effect of pain nursing combined with intravenous self-controlled analgesia pump on promoting the recovery speed of parturients after cesarean section. Methods: the subjects of this experiment...Objective: to explore the effect of pain nursing combined with intravenous self-controlled analgesia pump on promoting the recovery speed of parturients after cesarean section. Methods: the subjects of this experiment were 70 parturients who underwent cesarean section in Jiyang District People's Hospital of Ji’nan City, Shandong Province. The time interval was from April 2020 to March 2021. The cardinal number was assigned to the control group (routine care) and the even number was assigned to the observation group (pain care combined with intravenous automatic analgesia pump) with 35 cases in each group. The pain degree (VAS), incidence rate of pain side effects, physical rehabilitation speed, quality of life and nursing compliance of the two groups of parturients in different periods after operation were compared. Results: the VAS score of the observation group was lower than that of the control group (P<0.05), the incidence of pain and side effects of the observation group was lower than that of the control group (P0.05), the first time of exhausting air, removing urinary catheter, getting out of bed for the first time, the time of first lactation and the time of hospitalization of the observation group were shorter than that of the control group (P0.05), the quality of life of the observation group was higher than that of the control group (P0.05), and the compliance of the observation group in the implementation of clinical nursing work was higher than that of the control group (P0.05). Conclusion: pain nursing combined with intravenous self-controlled analgesia pump has good analgesic effect after cesarean section, and can promote the recovery rate of postpartum body, reduce the incidence of side effects, improve the nursing compliance of parturients and improve the quality of life of parturients. It is worthy of wide clinical application.展开更多
Objectives: To observe the curative effects and adverse reactions of recombinant human (rh)-endostatin injection combined with a TP regimen for treating patients with advanced ovarian cancer.Methods: Fifty-four patien...Objectives: To observe the curative effects and adverse reactions of recombinant human (rh)-endostatin injection combined with a TP regimen for treating patients with advanced ovarian cancer.Methods: Fifty-four patients with pathologically confirmed ovarian cancer were randomly divided into a combined treatment (intravenous pump of rh-endostatin + TP regimen) group and a control (single chemotherapy) group, twenty-seven patients in each group.All patients were given a conventional CT examination.The level of vascular endothelial growth factor (VEGF), the size of tumor before treatment, after 2 cycles and after 4 cycles of treatment were determined for the comparison of curative effects and adverse reactions.Results: The effective rate was 37.0％ (10/27) and disease control rate was 63.0％ (17/27) in the combined treatment group after 2 cycles of treatment.The effective rate was 25.9％ (7/27) and disease control rate was 63.0％ (17/27) in the control group.The comparison between these two groups showed no significant differences (P ＞ 0.05).The effective rate was 63.0％ (17/27) and disease control rate was 92.6％ (25/27) in the combined treatment group after 4 cycles of treatment.The effective rate was 29.6％ (8/27) and disease control rate was 63.0％ (17/27) in the control group.The effective rate and disease control rate between these two groups after 4 cycles of treatment showed significant differences (P ＜ 0.05).The incidences of cardiovascular toxicity, myelosuppression, sore muscles and joints, alopecia and gastrointestinal reaction was not significantly different between two groups (P ＞ 0.05).Conclusion: The pump delivery of rh-endostatin can down-regulate the expression of VEGF in ovarian cancer and has the better curative effect and slighter adverse reactions.Copyright 2015, Chinese Medical Association Production.Production and hosting by Elsevier B.V.on behalf of KeAi Communications Co., Ltd.This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/ by-nc-nd/4.0/).展开更多
文摘Objective: To explore the clinical effectiveness of combined use of intravenous pain pump with Parecoxib injection in alleviating pain in patients during the early postoperative period after thoracoscopic surgery. Methods: Eighty patients who underwent thoracoscopic surgery in a tertiary hospital were selected as the study subjects and randomly divided into two groups, with 40 patients in each group. The control group received routine postoperative treatment with intravenous pain pump, while the experimental group received Parecoxib in addition to the standard postoperative pain pump treatment. Visual Analog Scale (VAS) pain scores were used to evaluate postoperative pain relief in both groups, along with adverse reactions, postoperative complications, and patient satisfaction with pain relief. Results: Patients who received Parecoxib injection in addition to the routine use of intravenous pain pump had VAS pain scores lower than 3 points at 6 h, 12 h, 24 h, and 36 h postoperatively compared to those in the control group. The incidence of postoperative lung collapse, pleural effusion, and pulmonary infections was also significantly lower in the experimental group. The differences between the two groups were statistically significant (P Conclusion: Early combined use of Parecoxib injection in the early postoperative period after thoracoscopic surgery has shown good clinical efficacy. It can reduce the level of pain in patients, promote effective coughing and expectoration, facilitate early mobilization of patients, improve patient compliance, reduce complications, shorten hospital stay, and expedite patient recovery. Therefore, it is worth promoting the widespread clinical application of Parecoxib injection in this setting.
文摘Objective: to explore the effect of pain nursing combined with intravenous self-controlled analgesia pump on promoting the recovery speed of parturients after cesarean section. Methods: the subjects of this experiment were 70 parturients who underwent cesarean section in Jiyang District People's Hospital of Ji’nan City, Shandong Province. The time interval was from April 2020 to March 2021. The cardinal number was assigned to the control group (routine care) and the even number was assigned to the observation group (pain care combined with intravenous automatic analgesia pump) with 35 cases in each group. The pain degree (VAS), incidence rate of pain side effects, physical rehabilitation speed, quality of life and nursing compliance of the two groups of parturients in different periods after operation were compared. Results: the VAS score of the observation group was lower than that of the control group (P<0.05), the incidence of pain and side effects of the observation group was lower than that of the control group (P0.05), the first time of exhausting air, removing urinary catheter, getting out of bed for the first time, the time of first lactation and the time of hospitalization of the observation group were shorter than that of the control group (P0.05), the quality of life of the observation group was higher than that of the control group (P0.05), and the compliance of the observation group in the implementation of clinical nursing work was higher than that of the control group (P0.05). Conclusion: pain nursing combined with intravenous self-controlled analgesia pump has good analgesic effect after cesarean section, and can promote the recovery rate of postpartum body, reduce the incidence of side effects, improve the nursing compliance of parturients and improve the quality of life of parturients. It is worthy of wide clinical application.
文摘Objectives: To observe the curative effects and adverse reactions of recombinant human (rh)-endostatin injection combined with a TP regimen for treating patients with advanced ovarian cancer.Methods: Fifty-four patients with pathologically confirmed ovarian cancer were randomly divided into a combined treatment (intravenous pump of rh-endostatin + TP regimen) group and a control (single chemotherapy) group, twenty-seven patients in each group.All patients were given a conventional CT examination.The level of vascular endothelial growth factor (VEGF), the size of tumor before treatment, after 2 cycles and after 4 cycles of treatment were determined for the comparison of curative effects and adverse reactions.Results: The effective rate was 37.0％ (10/27) and disease control rate was 63.0％ (17/27) in the combined treatment group after 2 cycles of treatment.The effective rate was 25.9％ (7/27) and disease control rate was 63.0％ (17/27) in the control group.The comparison between these two groups showed no significant differences (P ＞ 0.05).The effective rate was 63.0％ (17/27) and disease control rate was 92.6％ (25/27) in the combined treatment group after 4 cycles of treatment.The effective rate was 29.6％ (8/27) and disease control rate was 63.0％ (17/27) in the control group.The effective rate and disease control rate between these two groups after 4 cycles of treatment showed significant differences (P ＜ 0.05).The incidences of cardiovascular toxicity, myelosuppression, sore muscles and joints, alopecia and gastrointestinal reaction was not significantly different between two groups (P ＞ 0.05).Conclusion: The pump delivery of rh-endostatin can down-regulate the expression of VEGF in ovarian cancer and has the better curative effect and slighter adverse reactions.Copyright 2015, Chinese Medical Association Production.Production and hosting by Elsevier B.V.on behalf of KeAi Communications Co., Ltd.This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/ by-nc-nd/4.0/).
