To explore the effect of rehabilitation nursing intervention on the rehabilitation of patients with sequelae of hypertensive intracerebral hemorrhage. Methods the patients with sequelae of hypertensive intracerebral h...To explore the effect of rehabilitation nursing intervention on the rehabilitation of patients with sequelae of hypertensive intracerebral hemorrhage. Methods the patients with sequelae of hypertensive intracerebral hemorrhage recently treated in our hospital were randomly divided into control group and observation group. The control group was given routine nursing scheme, and the observation group was given rehabilitation nursing intervention on the basis of the control group. Results after nursing intervention, the scores of quality of life in the observation group were significantly higher than those in the control group (P < 0.05). Conclusion rehabilitation nursing intervention in the nursing of patients with sequelae of hypertensive intracerebral hemorrhage can effectively improve the rehabilitation effect and improve the quality of life of patients, which is worthy of popularization and application. Generally speaking, as long as patients with intracerebral hemorrhage are awake and their body temperature, blood pressure, pulse and breathing are stable, there will be no neurological impairment. Rehabilitation treatment will begin 48 hours later. The sooner the rehabilitation treatment is, the better.展开更多
In the early days of the Covid-19 pandemic,China implemented the most stringent and serious emergency response.To understand the effect of such an emergency response strategy on the economic system,this study proposed...In the early days of the Covid-19 pandemic,China implemented the most stringent and serious emergency response.To understand the effect of such an emergency response strategy on the economic system,this study proposed a simultaneous overall estimation method using intracity travel intensity data.The overall effect is represented by the difference between intracity travel intensity with and without the emergency response.Using historical data and time series analysis,we compared intracity travel intensity post China’s implementation of the emergency response with predicted intracity travel intensity without such a response.The loss rates,defined by the proportion of intracity travel intensity loss,were calculated for 360 cities within 33 provincial-level regions in China based on data availability.We found that 30 days after the emergency response,21% of the cities saw over 80% recovery and 10% of the cities showed more than 90% recovery;45 days after the emergency response,more than 83% of the 360 cities witnessed 80% recovery.The correlation between gross domestic production loss rate and travel intensity loss rate was studied quantitatively to demonstrate the representativeness of the intracity travel intensity loss rate.This indicator was also used to analyze the spatial and temporal patterns of the effects on the economy.The results of this study can help us understand the economic effects caused by the early Covid-19 emergency response and the method can be a reference for fast and real-time economic loss estimation to support emergency response decision making under pandemic conditions.展开更多
Recent studies show that ion channels/transporters play important roles in fundamental cellular functions that would be involved in the cancer process. We review the evidence for their expression and functioning in hu...Recent studies show that ion channels/transporters play important roles in fundamental cellular functions that would be involved in the cancer process. We review the evidence for their expression and functioning in human gastric cancer (GC), and evaluate the potential of cellular physiological approach in clinical management. Various types of ion channels, such as voltage-gated K<sup>+</sup> channels, intracellular Cl<sup>-</sup> channels and transient receptor potential channels have been found to express in GC cells and tissues, and to control cell cycles. With regard to water channels, aquaporin 3 and 5 play an important role in the progression of GC. Regulators of intracellular pH, such as anion exchanger, sodium-hydrogen exchanger, vacuolar H<sup>+</sup>-ATPases and carbonic anhydrases are also involved in tumorigenesis of GC. Their pharmacological manipulation and gene silencing affect cellular behaviours, suggesting their potential as therapeutic targets for GC. Our studies indicate the intracellular Cl<sup>-</sup> concentration could act as a mediator of cellular signaling and control cell cycle progression in GC cells. Further, we demonstrate the cytocidal effects of hypotonic shock on GC cells, and indicate that the blockade of Cl<sup>-</sup> channels/transporters enhances these effects by inhibiting regulatory volume decrease. A deeper understanding of molecular mechanisms may lead to the discovery of these cellular physiological approaches as a novel therapeutic strategy for GC.展开更多
文摘To explore the effect of rehabilitation nursing intervention on the rehabilitation of patients with sequelae of hypertensive intracerebral hemorrhage. Methods the patients with sequelae of hypertensive intracerebral hemorrhage recently treated in our hospital were randomly divided into control group and observation group. The control group was given routine nursing scheme, and the observation group was given rehabilitation nursing intervention on the basis of the control group. Results after nursing intervention, the scores of quality of life in the observation group were significantly higher than those in the control group (P < 0.05). Conclusion rehabilitation nursing intervention in the nursing of patients with sequelae of hypertensive intracerebral hemorrhage can effectively improve the rehabilitation effect and improve the quality of life of patients, which is worthy of popularization and application. Generally speaking, as long as patients with intracerebral hemorrhage are awake and their body temperature, blood pressure, pulse and breathing are stable, there will be no neurological impairment. Rehabilitation treatment will begin 48 hours later. The sooner the rehabilitation treatment is, the better.
基金supported by the National Natural Science Foundation of China[Grant Number 41807504,41907393]Fundamental Research Funds for Central Universities[WUT 2020IVB023],China。
文摘In the early days of the Covid-19 pandemic,China implemented the most stringent and serious emergency response.To understand the effect of such an emergency response strategy on the economic system,this study proposed a simultaneous overall estimation method using intracity travel intensity data.The overall effect is represented by the difference between intracity travel intensity with and without the emergency response.Using historical data and time series analysis,we compared intracity travel intensity post China’s implementation of the emergency response with predicted intracity travel intensity without such a response.The loss rates,defined by the proportion of intracity travel intensity loss,were calculated for 360 cities within 33 provincial-level regions in China based on data availability.We found that 30 days after the emergency response,21% of the cities saw over 80% recovery and 10% of the cities showed more than 90% recovery;45 days after the emergency response,more than 83% of the 360 cities witnessed 80% recovery.The correlation between gross domestic production loss rate and travel intensity loss rate was studied quantitatively to demonstrate the representativeness of the intracity travel intensity loss rate.This indicator was also used to analyze the spatial and temporal patterns of the effects on the economy.The results of this study can help us understand the economic effects caused by the early Covid-19 emergency response and the method can be a reference for fast and real-time economic loss estimation to support emergency response decision making under pandemic conditions.
文摘Recent studies show that ion channels/transporters play important roles in fundamental cellular functions that would be involved in the cancer process. We review the evidence for their expression and functioning in human gastric cancer (GC), and evaluate the potential of cellular physiological approach in clinical management. Various types of ion channels, such as voltage-gated K<sup>+</sup> channels, intracellular Cl<sup>-</sup> channels and transient receptor potential channels have been found to express in GC cells and tissues, and to control cell cycles. With regard to water channels, aquaporin 3 and 5 play an important role in the progression of GC. Regulators of intracellular pH, such as anion exchanger, sodium-hydrogen exchanger, vacuolar H<sup>+</sup>-ATPases and carbonic anhydrases are also involved in tumorigenesis of GC. Their pharmacological manipulation and gene silencing affect cellular behaviours, suggesting their potential as therapeutic targets for GC. Our studies indicate the intracellular Cl<sup>-</sup> concentration could act as a mediator of cellular signaling and control cell cycle progression in GC cells. Further, we demonstrate the cytocidal effects of hypotonic shock on GC cells, and indicate that the blockade of Cl<sup>-</sup> channels/transporters enhances these effects by inhibiting regulatory volume decrease. A deeper understanding of molecular mechanisms may lead to the discovery of these cellular physiological approaches as a novel therapeutic strategy for GC.
