Background Vibrotactile feedback systems are widely used in assistive technology,wearable devices,and virtual environments to deliver precise tactile information.The timing of interstimulus intervals(ISIs)plays a crit...Background Vibrotactile feedback systems are widely used in assistive technology,wearable devices,and virtual environments to deliver precise tactile information.The timing of interstimulus intervals(ISIs)plays a critical role in determining how accurately users perceive and interpret vibrotactile patterns.The optimal use of ISIs can increase the effectiveness of these systems,improve user interaction,and enable reliable,intuitive feedback in diverse applications.We examined how different interstimulus intervals ISIs impact the accuracy of vibrotactile pattern recognition.Methods Participants wore a forearm-mounted device with six voice coil actuators arranged in a 3×2 grid,delivering Braille-based vibrotactile patterns sequentially at ISIs ranging from 10 to 2500 ms.Eight participants performed identification tasks involving Icelandic Braille patterns categorized as either short(2-3 actuators)or long(4-5 actuators).A repeated measures ANOVA was conducted to assess the effects of ISI,pattern type,and practice(across two testing blocks)on pattern recognition accuracy.Results For short patterns,accuracy was highest(92%-98%)at ISIs of 50-700 ms,with peak performance at 300 ms.For long patterns,accuracy reached 86%-94%at ISIs of 100-500 ms,peaking at 400 ms.Participants were more accurate with short patterns,and performance improved significantly over time for both short and long patterns,highlighting the importance of training for vibrotactile pattern recognition.Conclusions These results underscore the importance of careful selection of ISIs in vibrotactile feedback systems for accurate pattern identification.The findings provide valuable insights for conveying tactile information using wearable devices,contributing to better tactile feedback and performance in applications requiring precise vibrotactile information delivery.展开更多
Classic paired associative stimulation can improve synaptic plasticity,as demonstrated by animal expe riments and human clinical trials in spinal cord injury patients.Paired associative magnetic stimulation(dual-targe...Classic paired associative stimulation can improve synaptic plasticity,as demonstrated by animal expe riments and human clinical trials in spinal cord injury patients.Paired associative magnetic stimulation(dual-target peripheral and central magnetic stimulation)has been shown to promote neurologic recove ry after stroke.However,it remains unclear whether paired associative magnetic stimulation can promote recovery of lower limb motor dysfunction after spinal cord injury.We hypothesize that the curre nt caused by central and peripheral magnetic stimulation will conve rge at the synapse,which will promote synapse function and improve the motor function of the relevant muscles.Therefore,this study aimed to examine the effects of paired associative magnetic stimulation on neural circuit activation by measuring changes in motor evoked and somatosensory evoked potentials,motor and sensory function of the lower limbs,functional health and activities of daily living,and depression in patients with spinal co rd injury.We will recruit 110 thora cic spinal trauma patients treated in the Department of Spinal Cord Injury,China Rehabilitation Hospital and randomly assign them to expe rimental and control groups in a 1:1 ratio.The trial group(n=55)will be treated with paired associative magnetic stimulation and conventional rehabilitation treatment.The control group(n=55)will be treated with sham stimulation and co nventional rehabilitation treatment.Outcomes will be measured at four time points:baseline and 4,12,and 24 wee ks after the start of inte rvention(active or sham paired associative magnetic stimulation).The primary outcome measure of this trial is change in lower limb American Spinal Injury Association Impairment Scale motor function score from baseline to last follow-up.Secondary outcome measures include changes in lower limb American Spinal Injury Association sensory function sco re,motor evoked potentials,sensory evoked potentials,modified Ashwo rth scale score,Maslach Burnout Invento ry score,and Hamilton Depression Scale score over time.Motor evoked potential latency reflects corticospinal tract transmission time,while amplitude reflects recruitment ability;both measures can help elucidate the mechanism underlying the effect of paired associative magnetic stimulation on synaptic efficiency.Adve rse events will be recorded.Findings from this trial will help to indicate whether paired associative magnetic stimulation(1)promotes recove ry of lower limb sensory and motor function,reduces spasticity,and improves quality of life;(2)promotes neurologic recovery by increasing excitability of spinal cord motor neurons and stimulating synaptic plasticity;and(3)improves rehabilitation outcome in patients with spinal cord injury.Recruitment for this trial began in April 2021 and is currently ongoing.It was approved by the Ethics Committee of Yangzhi Affiliated Rehabilitation Hospital of Tongji University,China(approval No.YZ2020-018)on May 18,2020.The study protocol was registered in the Chinese Clinical Trial Registry(registration number:ChiCTR2100044794)on March 27,2021(protocol version 1.0).This trial will be completed in April 2022.展开更多
基金Supported by the Icelandic Technological Development Fund(Project No.1910271).
文摘Background Vibrotactile feedback systems are widely used in assistive technology,wearable devices,and virtual environments to deliver precise tactile information.The timing of interstimulus intervals(ISIs)plays a critical role in determining how accurately users perceive and interpret vibrotactile patterns.The optimal use of ISIs can increase the effectiveness of these systems,improve user interaction,and enable reliable,intuitive feedback in diverse applications.We examined how different interstimulus intervals ISIs impact the accuracy of vibrotactile pattern recognition.Methods Participants wore a forearm-mounted device with six voice coil actuators arranged in a 3×2 grid,delivering Braille-based vibrotactile patterns sequentially at ISIs ranging from 10 to 2500 ms.Eight participants performed identification tasks involving Icelandic Braille patterns categorized as either short(2-3 actuators)or long(4-5 actuators).A repeated measures ANOVA was conducted to assess the effects of ISI,pattern type,and practice(across two testing blocks)on pattern recognition accuracy.Results For short patterns,accuracy was highest(92%-98%)at ISIs of 50-700 ms,with peak performance at 300 ms.For long patterns,accuracy reached 86%-94%at ISIs of 100-500 ms,peaking at 400 ms.Participants were more accurate with short patterns,and performance improved significantly over time for both short and long patterns,highlighting the importance of training for vibrotactile pattern recognition.Conclusions These results underscore the importance of careful selection of ISIs in vibrotactile feedback systems for accurate pattern identification.The findings provide valuable insights for conveying tactile information using wearable devices,contributing to better tactile feedback and performance in applications requiring precise vibrotactile information delivery.
基金the National Key Research and Development Program of China,No.2020YFC2004202(to DSX)the National Natural Science Foundation of China(General Program),Nos.81772453,81974358(to DSX)Scientific Research Project of Yangzhi Rehabilitation Hospital Affliated to Tongji University,No.KYPY202006(to TTS)。
文摘Classic paired associative stimulation can improve synaptic plasticity,as demonstrated by animal expe riments and human clinical trials in spinal cord injury patients.Paired associative magnetic stimulation(dual-target peripheral and central magnetic stimulation)has been shown to promote neurologic recove ry after stroke.However,it remains unclear whether paired associative magnetic stimulation can promote recovery of lower limb motor dysfunction after spinal cord injury.We hypothesize that the curre nt caused by central and peripheral magnetic stimulation will conve rge at the synapse,which will promote synapse function and improve the motor function of the relevant muscles.Therefore,this study aimed to examine the effects of paired associative magnetic stimulation on neural circuit activation by measuring changes in motor evoked and somatosensory evoked potentials,motor and sensory function of the lower limbs,functional health and activities of daily living,and depression in patients with spinal co rd injury.We will recruit 110 thora cic spinal trauma patients treated in the Department of Spinal Cord Injury,China Rehabilitation Hospital and randomly assign them to expe rimental and control groups in a 1:1 ratio.The trial group(n=55)will be treated with paired associative magnetic stimulation and conventional rehabilitation treatment.The control group(n=55)will be treated with sham stimulation and co nventional rehabilitation treatment.Outcomes will be measured at four time points:baseline and 4,12,and 24 wee ks after the start of inte rvention(active or sham paired associative magnetic stimulation).The primary outcome measure of this trial is change in lower limb American Spinal Injury Association Impairment Scale motor function score from baseline to last follow-up.Secondary outcome measures include changes in lower limb American Spinal Injury Association sensory function sco re,motor evoked potentials,sensory evoked potentials,modified Ashwo rth scale score,Maslach Burnout Invento ry score,and Hamilton Depression Scale score over time.Motor evoked potential latency reflects corticospinal tract transmission time,while amplitude reflects recruitment ability;both measures can help elucidate the mechanism underlying the effect of paired associative magnetic stimulation on synaptic efficiency.Adve rse events will be recorded.Findings from this trial will help to indicate whether paired associative magnetic stimulation(1)promotes recove ry of lower limb sensory and motor function,reduces spasticity,and improves quality of life;(2)promotes neurologic recovery by increasing excitability of spinal cord motor neurons and stimulating synaptic plasticity;and(3)improves rehabilitation outcome in patients with spinal cord injury.Recruitment for this trial began in April 2021 and is currently ongoing.It was approved by the Ethics Committee of Yangzhi Affiliated Rehabilitation Hospital of Tongji University,China(approval No.YZ2020-018)on May 18,2020.The study protocol was registered in the Chinese Clinical Trial Registry(registration number:ChiCTR2100044794)on March 27,2021(protocol version 1.0).This trial will be completed in April 2022.
