The hydro-mechanical responses of vegetated deposited slopes are complex and far from clear.On one hand,the soils in deposited slopes are typically poorly consolidated and widely graded,making them vulnerable to inter...The hydro-mechanical responses of vegetated deposited slopes are complex and far from clear.On one hand,the soils in deposited slopes are typically poorly consolidated and widely graded,making them vulnerable to internal erosion during rainfall infiltration.On the other hand,vegetation plays a significant role in influencing the hydro-mechanical properties of the soil at the slope surface.This paper presents a coupled seepage-erosion model to investigate the rainfall-induced internal erosion process within vegetated deposited slopes and its impact on slope stability.The detailed seepage-erosion coupling processes were simulated for a series of 1D rooted soil columns with varying root distributions,as well as 2D vegetated layered slopes under both light and heavy rainfall conditions.The numerical results reveal that roots can significantly mitigate rainfall-induced internal erosion,even with shallow root lengths.However,their protective effect on the slope increases as the root density in the superficial soil layer increases.Transpiration can rapidly restore matric suction in the shallow soil during rain intervals,slowing the rainfall-induced seepage-erosion process and thereby increasing slope stability.However,in the absence of transpiration,roots may either accelerate or inhibit the seepage-erosion process,depending on the specific rainfall conditions.展开更多
BACKGROUND Bilateral internal mammary arteries(BIMAs)as the most advanced surgical option for coronary artery bypass grafting(CABG)are usually recommended for younger patients without traditional risk factors.This stu...BACKGROUND Bilateral internal mammary arteries(BIMAs)as the most advanced surgical option for coronary artery bypass grafting(CABG)are usually recommended for younger patients without traditional risk factors.This study compares outcomes in propensity score-matched patients aged over 70 years who received BIMAs versus those who received a single internal mammary artery(SIMA).METHODS From 2013 to 2024,8123 patients underwent primary CABG for multivessel coronary artery disease at our institution.BIMA grafting was performed in 1233 patients(15.17%),with in situ BIMA grafting in 290 patients(3.57%).For in situ BIMA group,the right internal mammary artery was used to revascularize the right coronary artery,while the left internal mammary artery was utilized for the left anterior descending artery.BIMA patients aged over 70 years(n=79)were compared with SIMA patients(n=79)using propensity score matching.Primary outcome was all-cause mortality at 30 days and 8 years.Secondary outcomes included length of hospital stay,incidence of postoperative major adverse cardiovascular and cerebrovascular events,sternal wound infection and the need for subsequent percutaneous revascularization.RESULTS There was no difference in immediate postoperative primary and secondary outcomes.Mean follow-up was 8.3±1.0 years with an 8-year freedom from death of 67.08%±1.1%in the BIMA group versus 58.22%±0.9%in the SIMA group(P<0.05).CONCLUSIONS BIMAs as in situ grafts can be successfully used in CABG for patients aged 70 years and older.Consequently,the refined techniques for constructing internal mammary artery grafts used in this study challenge traditionally accepted limitations regarding the use of BIMAs.展开更多
Objective: To clarify the role of the “Three Threes” method in clinical teaching of internal jugular vein puncture and explore improvements in teaching methods. Methods: A doctor was assigned to the induction room o...Objective: To clarify the role of the “Three Threes” method in clinical teaching of internal jugular vein puncture and explore improvements in teaching methods. Methods: A doctor was assigned to the induction room of the Second Affiliated Hospital of Naval Medical University (Shanghai Changzheng Hospital) for two months. The time required for catheterization, the first puncture success rate, and occurrence of puncture-related complications were compared before and after learning the “Three Threes” method. Results: Using the “Three Threes” method reduced the catheterization time by 43%, increased the first puncture success rate by 17%, and led to fewer puncture-related complications. Conclusion: The application of the “Three Threes” method not only improves the success rate of internal jugular vein puncture but also reduces complications, making it easier for students to master the technique.展开更多
Convection driven by a spatially non-uniform internal heat source between two horizontal isothermal walls is studied by theoretical analysis and numerical simulation,in order to explore the bounds of the temperature a...Convection driven by a spatially non-uniform internal heat source between two horizontal isothermal walls is studied by theoretical analysis and numerical simulation,in order to explore the bounds of the temperature and the vertical heat flux.Specifically,the rigorous lower bound of the weighted average temperature<QT>is derived analytically,by decomposing the temperature field into a background profile and a fluctuation part.This bound obtained for the first time to consider non-uniform heat sources is found to be compatible with the existing bound obtained in uniform internal heat convection.Of physical importance,an analytical relationship is derived as an inequality connecting<QT>and the average vertical heat flux<wT>,by employing the average heat flux on the bottom wall(qb)as an intermediary variable.It clarifies the intrinsic relation between the lower bound of<QT>and the upper bound of<wT>,namely,these two bounds are essentially equivalent providing an easy way to obtain one from another.Furthermore,the analytical bounds are extensively demonstrated through a comprehensive series of direct numerical simulations.展开更多
Internal erosion occurs when fine particles escape from the soil driven by seepage flow,which is considered to be the crucial factor causing the failure of earth structures filled with gravelly soil.The objective of t...Internal erosion occurs when fine particles escape from the soil driven by seepage flow,which is considered to be the crucial factor causing the failure of earth structures filled with gravelly soil.The objective of this paper is to suggest an appropriate method to assess internal erosion potential of gravelly soil.By analyzing the sensitivity of soil material to internal erosion,the variable(Dc15/df85)max and the content of coarse particles(Pc)are selected as the evaluation indexes(Dc15 and df85 are the diameters of 15%mass passing in the coarse component and 85%mass passing in the fine component,respectively).A series of gravelly soils with different particle size distributions are tested for internal erosion by the self-made permeameter.Based on the test results,an evaluation method for the internal erosion of gravelly soil is proposed.Gravelly soil is prone to internal erosion when 60%≤Pc<95%and(Dc15/df85)max≥9.5.The proposed method shows good accuracy in evaluating the internal erosion of 36 soil samples from other studies,which confirms the reliability of the method.The proposed method makes it possible to accurately assess internal erosion of gravelly soil,and an alternative method is provided for engineers to determine whether there is a risk of internal erosion in earth structures consisting of gravelly soil.展开更多
A corrosion defect is recognized as one of the most severe phenomena for high-pressure pipelines,especially those served for a long time.Finite-element method and empirical formulas are thereby used for the strength p...A corrosion defect is recognized as one of the most severe phenomena for high-pressure pipelines,especially those served for a long time.Finite-element method and empirical formulas are thereby used for the strength prediction of such pipes with corrosion.However,it is time-consuming for finite-element method and there is a limited application range by using empirical formulas.In order to improve the prediction of strength,this paper investigates the burst pressure of line pipelines with a single corrosion defect subjected to internal pressure based on data-driven methods.Three supervised ML(machine learning)algorithms,including the ANN(artificial neural network),the SVM(support vector machine)and the LR(linear regression),are deployed to train models based on experimental data.Data analysis is first conducted to determine proper pipe features for training.Hyperparameter tuning to control the learning process is then performed to fit the best strength models for corroded pipelines.Among all the proposed data-driven models,the ANN model with three neural layers has the highest training accuracy,but also presents the largest variance.The SVM model provides both high training accuracy and high validation accuracy.The LR model has the best performance in terms of generalization ability.These models can be served as surrogate models by transfer learning with new coming data in future research,facilitating a sustainable and intelligent decision-making of corroded pipelines.展开更多
The deviations of trajectory and attitude angle for internal store separation are evaluated by two wind tunnel test methods.One is the Freedrop Test(FDT),which is known as unsteady and time-dependent method of scaled ...The deviations of trajectory and attitude angle for internal store separation are evaluated by two wind tunnel test methods.One is the Freedrop Test(FDT),which is known as unsteady and time-dependent method of scaled model.The other is the Captive Trajectory System(CTS)test,which is usually regarded as a quasi-steady and time-averaged test technology.The result shows that there is a streamwise adverse pressure gradient on the cavity resulting in a nose-up pitching moment coefficient(>0)acting on the store model.When the initial pitch angular velocity is 0,the store exits the shear-layer with a nose-up pitch attitude causing the store to climb back towards and collide with the aircraft.However,the store passes through the shear-layer into the freestream with a nose-down pitch,which causes a successful separation event when the initial pitch angular velocity<0.The pitch angle obtained by unsteady test method is different from that by quasisteady test method.The time-dependent test includes the aerodynamic force induced by pitch angular velocity whereas the time-averaged method(CTS)cannot reflect the effect of unsteady aerodynamic force.The deviation of vertical displacement is not obvious for FDT and CTS test since the store has an initial vertical velocity,which is dominant for the vertical displacement.This means that the highly unsteady flow can create unpredictability in aerodynamic pitching moment of the store,which can lead to the deviation of pitch angle for internal store separation.展开更多
Wafer curvature method has been applied to determine the internal stress in the films using Stoney＇s equation.During the film deposition,the wafer fixation on the sample holder will restrict the deformation of the re...Wafer curvature method has been applied to determine the internal stress in the films using Stoney＇s equation.During the film deposition,the wafer fixation on the sample holder will restrict the deformation of the rectangle-shaped wafer,which may result in the stress datum difference along length and width direction.In this paper,the effect of wafer size and the wafer fixation on the TiN film internal stress measured by wafer curvature method was discussed.The rectangle-shaped wafers with different length/width ratios（L/W=1：1,2：1,3：1 and 4：1） were fixed as a cantilever beam.After the TiN films deposition,the profiles of the film/wafer were measured using a stylus profilometer and then the internal stress was calculated using the Stoney equation in the film.The results showed that the fixed end of the wafers limited to some degree the curvature of the wafers along the width direction.For film internal stress measured by wafer curvature method,the wafer profile should be scanned along the length direction and the scan distance should be greater than or equal to half of wafer length.When the length/width ratio of the wafer reached 3：1,the wafer curvature and the calculated stress were basically the same at different positions along the length direction.For film internal stress measured by wafer curvature method,it was recommended that the length/width ratio of wafer should be considered to be greater than or equal to 3：1,and the deformed profile was scanned along the length direction.展开更多
Objective:To observe and analyze the application of the bedside rhetorical teaching method in teaching nursing interns.Methods:A total of 64 nursing interns in the gastroenterology department of our hospital from July...Objective:To observe and analyze the application of the bedside rhetorical teaching method in teaching nursing interns.Methods:A total of 64 nursing interns in the gastroenterology department of our hospital from July 2022 to May 2023 were randomly divided into two groups,32 cases in the control group and 32 cases in the intervention group.The control group was given conventional teaching methods,and the intervention group was given the bedside rhetorical teaching method on the basis of the conventional teaching.The differences in the methods of teaching between the two groups were compared after the end of the internship,and there was a statistically significant difference with P<0.05.Results:The scores of the interns in the intervention group were significantly better than those of the control group in theoretical knowledge,communication skills,and case analysis items(P<0.05).Conclusion:The bedside rhetorical teaching method transforms classroom education into bedside teaching,which enables the interns to apply the theoretical knowledge to clinical practice,and has a higher improvement in the three aspects of disease knowledge,communication skills,and case analysis,cultivates the interns’comprehensive clinical skills,and lays a good foundation for the future entry into the nursing field.展开更多
Laser ablation coupled with inductively coupled plasma-mass spectrometry (LA-ICP-MS) calibration was conducted with multiple spot analyses on eleven intact rock samples using both an internal standard (IS) method and ...Laser ablation coupled with inductively coupled plasma-mass spectrometry (LA-ICP-MS) calibration was conducted with multiple spot analyses on eleven intact rock samples using both an internal standard (IS) method and a modified constant-sum (MCS) method. Methods were then compared for reported bulk elemental composition of the rocks. The MCS method was based on the sum of eight major elements, which is spatially more stable than one single major ele-ment as used in the IS method, and is quite constant among different rock samples. Calibrations were performed with standard reference materials NIST SRM 610, 612, 614, and 616. Little difference was found between using a single standard and a set of standards, because of the good linearity shown by the reference materials. Comparison of the two calibration methods shows that the MCS method produced better and more stable results than the IS method for heterogeneous samples. With the MCS method, approximately 94% to 95% of the total measurements are within the range of ±100% relative deviation, compared with 82% to 86% with the IS method. The IS method resulted insubstantial overestimations for some rock samples (e.g., 648% for Basalt BCR-2 using NIST SRM 610 as the calibration standard), while the largest deviation with the MCS method was 216% for U in Eagle Ford shale #80 sample. For Quartz latite QLO-1, a relative homogeneous sample, the IS method generated slightly better results than the MCS method. Regardless of method, spatially heterogeneous distribution of elements in the intact rock at the scale of the laser spot is considered to be the main reason for the large relative deviations seen in our work compared to published results.展开更多
The internal standard (IS) method is the best method for the analysis of samples, as it is independent of errors in injection volume, changes in sample volumes, and changes in sensitivity of the detector, etc. Use of ...The internal standard (IS) method is the best method for the analysis of samples, as it is independent of errors in injection volume, changes in sample volumes, and changes in sensitivity of the detector, etc. Use of an internal standard allows for the correction of losses due to sample clean-up of complex samples. An ideal IS is a compound that has properties very similar to, and that behaves as the compounds to be analysed. Ideally, only in the last step of analysis (HPLC), the IS should be well separated from the compounds of the mixture to be analysed. After testing several existing compounds with negative results, we decided to synthesise the 19-O-β-D-galactopyranosyl-13-O-β-D-glucopyranosyl-steviol as IS. This is the 19-galactosyl ester of steviolmonoside (13-O-β-D-glucopyranosyl-steviol). The IS was made according to published methods. Steviolmonoside (SM) was made from purified commercial rubusoside (Rub) by refluxing it in 10% KOH for 2 h. SM was precipitated and crystallized from MeOH. The hydroxyls of the glucose unit of SM were protected by acetylation. The acetylated SM was crystallized from acetone and dissolved in 1,2-dichloroethane. Then Ag2CO3 on Celite and tetra-acetylated galactopyranosyl bromide were added and the mixture was refluxed for 2 h. After cooling, BaO in MeOH was added to remove the acetyl groups. The 1,2-dichloroethane fraction was then extracted three times with equal volumes of water and the water fraction containing the IS was further purified on a C18 flash chromatography column. Traces of unreacted SM were removed by preparative HPLC on an Alltima C18 column (250 mm × 22 mm, particle size 10 μm) with AcCN:water (35:65, 20 ml/min). Detection was at 210 nm (KNAUER, “Smartline” UV detector 2500). The collected IS fraction from the HPLC was completely dried. Mixtures of steviol glycosides (SVglys) containing IS could be purified over SPE cartridges without change of the SVgly over IS ratio. The calibration curves for rebaudioside A (RebA) and stevioside (ST) were linear between 0.012 and 0.95 and between 0.013 and 1.13 mM for RebA and ST, respectively. The accuracy was checked by the standard addition method. It was concluded that the IS method gives an excellent precision and accuracy.展开更多
[Objective]This study was to establish a rapid,specific and simple method for quantitative determination of tetrachlorantraniliprole by 1H NMR.[Method]1H NMR spectroscopy was acquired with deuterium DMSO as the solven...[Objective]This study was to establish a rapid,specific and simple method for quantitative determination of tetrachlorantraniliprole by 1H NMR.[Method]1H NMR spectroscopy was acquired with deuterium DMSO as the solvent and maleic acid as internal standard under the conditions of temperature 25℃,pulses width 8.0μs,delay time 5 s,and scanning times 8.[Result]The hydrogen proton peaks of tetrachlorantraniliprole(δ=10.55)and maleic acid(δ=6.27)were taken as quantitative peaks.The peak area ratio y(As/Ar)and mass ratio x(ms/mr)were linearly regressed,and the correlation coefficient was 0.9999.The RSD value of repeatability test was 0.38%,and the RSD value of stability test was 0.77%.The content of tetrachlorantraniliprole was determined as 99.6%.[Conclusion]1H NMR spectroscopy can be used for quantitative determination of tetrachlorantraniliprole without standard reference,which is rapid,accurate and simple.展开更多
Mercury and its organic compounds have been of severe concern worldwide due to their damage to the ecosystem and human health. The development of effective and affordable technology to monitor and signal the presence ...Mercury and its organic compounds have been of severe concern worldwide due to their damage to the ecosystem and human health. The development of effective and affordable technology to monitor and signal the presence of bioavailable mercury is an urgent need.The Mer gene is a mercury-responsive resistant gene, and a mercury-sensing recombinant luminescent bacterium using the Mer gene was constructed in this study. The mer operon from marine Pseudomonas putida strain SP1 was amplified and fused with prompterless lux CDABE in the p UCD615 plasmid within Escherichia coli cells, resulting in p THE30–E. coli.The recombinant strain showed high sensitivity and specificity. The detection limit of Hg^2＋was 5 nmol/L, and distinct luminescence could be detected in 30 min. Cd^2＋, Cu^2＋, Zn^2＋, Ca^2＋,Pb^2＋, Mg^2＋, Mn^2＋, and Al^3＋did not interfere with the detection over a range of 10-5–1 m M.Application of recombinant luminescent bacteria testing in environmental samples has been a controversial issue： especially for metal-sensing recombinant strains, false negatives caused by high cytotoxicity are one of the most important issues when applying recombinant luminescent bacteria in biomonitoring of heavy metals. In this study, by establishing an internal standard approach, the false negative problem was overcome;furthermore, the method can also help to estimate the suspected mercury concentration,which ensures high detection sensitivity of bioavailable Hg2＋.展开更多
Uranium carbide kernels is one special fuel materials for the High-Temperature Gas-cooled Reactor[1], which can improve nuclear fuel’s efficiency, longevity, and safety. In the fabrication process, there are many fac...Uranium carbide kernels is one special fuel materials for the High-Temperature Gas-cooled Reactor[1], which can improve nuclear fuel’s efficiency, longevity, and safety. In the fabrication process, there are many factors affect the quality of the kernels, such as subsequent ageing, HMTA/uranium mole ratio, gelation forming temperature, washing step, heating rate of the calcine and sinter step, one important step is the dispersing carbon into the solution stock of HMTA and urea[2;3].展开更多
Fins are extensively utilized in heat exchangers and various industrial applications as they are lightweight and can benefit in various systems,including electronic cooling devices and automotive components,owing to t...Fins are extensively utilized in heat exchangers and various industrial applications as they are lightweight and can benefit in various systems,including electronic cooling devices and automotive components,owing to their adaptable design.Furthermore,spine fins are introduced to improve performance in applications such as automotive radiators.They can be shaped in different ways and constructed from a collection of materials.Inspired by this,the present model examines the effects of internal heat generation and radiation-convection on the thermal distribution in a wetted convex-shaped spine fin.Using dimensionless terms,the proposed fin model involving a governing nonlinear ordinary differential equation(ODE)is transformed into a dimensionless form.The study uses the operational matrix with the Charlier polynomial collocation method(OMCCM)to ensure precise and computationally efficient numerical solutions for the dimensionless equation.In order to aid in the analysis of thermal performance,the importance of major parameters on the temperature profile is graphically illustrated.The main outcome of the study reveals that as the radiation-conductive,wet,and convective-conductive parameters increase,the heat transfer rate progressively improves.Conversely,the ambient temperature and internal heat generation parameters show an inverse relationship.展开更多
In this paper, based on the idea of finite element method, the initial parametric method in bending, problem of a beam is extended to analyse the bar-system structure by employing Dirac function and llcavisidc step fu...In this paper, based on the idea of finite element method, the initial parametric method in bending, problem of a beam is extended to analyse the bar-system structure by employing Dirac function and llcavisidc step function.Then a new method for analysing the internal forces and deformations of bar-system structure in space is suggested by improving the mixed method in statically indeterminate structure.The inferred process and obtained answer will be more succinct and accurate when the problem of internal forces and deformations of bar-system structure is analysed by using the new method provided in this paper.展开更多
In this study,the impacts of internal heat generation on heat transfer enhancement of porous fin is theoretical investigated using differential transform method.The parametric studies reveal that porosity enhances the...In this study,the impacts of internal heat generation on heat transfer enhancement of porous fin is theoretical investigated using differential transform method.The parametric studies reveal that porosity enhances the fin heat dissipating capacity but the internal heat generation decreases the heat enhancement capacity of extended surface.Also,it is established that when the internal heat parameter increases to some certain values,some negative effects are recorded where the fin stores heat rather than dissipating it.This scenario defeats the prime purpose of the cooling fin.Additionally,it is established in the present study that the limiting value of porosity parameter for thermal stability for the passive device increases as internal heat parameter increases.This shows that although the internal heat parameter can help assist higher range and value of thermal stability of the fin,it produces negative effect which greatly defeats the ultimate purpose of the fin.The results in the work will help in fin design for industrial applications where internal heat generation is involved.展开更多
The hatches for inspecting are usually designed with elliptical holes in airplane structures, so computation of the stress intensity factor of three dimensional crack at elliptical holes is pivotal for damage toleranc...The hatches for inspecting are usually designed with elliptical holes in airplane structures, so computation of the stress intensity factor of three dimensional crack at elliptical holes is pivotal for damage tolerance analysis of these structures. In this paper, weight function is derived for a two dimensional through cracks at elliptical holes by applying a compounding method. Stress intensity factor formulas for an internal surface semi-elliptical crack in elliptical holes are obtained wing the three dimensional weight function method. Stress intensity factors for an internal surface semi-elliptical crack in elliptical holes under remote tension are computed. At the same time, research on how radius of curvature for elliptical holes affect stress intensity factors was conducted. Stress intensity factors decrease when radius of curvature increases. Some results and conclusions which are of practical value are given.展开更多
Objective: to explore the application effect of situational teaching method in the overall nursing of internal medicine. Methods: select our hospital in January 2019 to January 2021 accepted 196 practice nurses as res...Objective: to explore the application effect of situational teaching method in the overall nursing of internal medicine. Methods: select our hospital in January 2019 to January 2021 accepted 196 practice nurses as research object, through the random group, divided into two groups, each group 98, a group set into group A, the conventional teaching method, another group set into group B, in routine teaching at the same time, the implementation of situational teaching method, compare the two groups of practice nurses theory assessment results and satisfaction. Results: 95.92% of the theoretical scores in group B was higher than 82.65% in Group A;94.90% of trainee nurses in Group B were higher than 80.61% in Group A;Total score of practice nurses (95.37 ± 105.58) was higher than that of (88.22 ± 10.26) in Group B. Conclusion: when training the internal practice nurses, the situational teaching method has good application effect, which can not only improve the mastery of relevant theoretical knowledge, but also obtain the higher satisfaction of practice nurses and improve the views of practice nurses on their own work, which can be promoted on a large scale.展开更多
There is an old saying,“Give a man a fish,and he will eat for a day.Teach a man to fish,and he will eat for the rest of his life.”In clinical teaching,students should not only be taught about diseases,but their inte...There is an old saying,“Give a man a fish,and he will eat for a day.Teach a man to fish,and he will eat for the rest of his life.”In clinical teaching,students should not only be taught about diseases,but their intelligence should also be cultivated,along with their analytical,comprehension,and independent learning skills.The ability to solve problems enables students to think independently and acquire knowledge.This is known as the heuristic method of teaching.In this study,we mainly analyze the application value of the heuristic method in the clinical teaching of internal medicine.展开更多
基金supported by National Natural Science Foundation of China(Grant No.42372330)Science and Technology Research Program of Institute of Mountain Hazards and Environment,Chinese Academy of Sciences(Grant No.IMHE-CXTD-01-IMHE-ZYTS-12)Sichuan Science and Technology Program(Grant No.2024NSFSC0102).
文摘The hydro-mechanical responses of vegetated deposited slopes are complex and far from clear.On one hand,the soils in deposited slopes are typically poorly consolidated and widely graded,making them vulnerable to internal erosion during rainfall infiltration.On the other hand,vegetation plays a significant role in influencing the hydro-mechanical properties of the soil at the slope surface.This paper presents a coupled seepage-erosion model to investigate the rainfall-induced internal erosion process within vegetated deposited slopes and its impact on slope stability.The detailed seepage-erosion coupling processes were simulated for a series of 1D rooted soil columns with varying root distributions,as well as 2D vegetated layered slopes under both light and heavy rainfall conditions.The numerical results reveal that roots can significantly mitigate rainfall-induced internal erosion,even with shallow root lengths.However,their protective effect on the slope increases as the root density in the superficial soil layer increases.Transpiration can rapidly restore matric suction in the shallow soil during rain intervals,slowing the rainfall-induced seepage-erosion process and thereby increasing slope stability.However,in the absence of transpiration,roots may either accelerate or inhibit the seepage-erosion process,depending on the specific rainfall conditions.
文摘BACKGROUND Bilateral internal mammary arteries(BIMAs)as the most advanced surgical option for coronary artery bypass grafting(CABG)are usually recommended for younger patients without traditional risk factors.This study compares outcomes in propensity score-matched patients aged over 70 years who received BIMAs versus those who received a single internal mammary artery(SIMA).METHODS From 2013 to 2024,8123 patients underwent primary CABG for multivessel coronary artery disease at our institution.BIMA grafting was performed in 1233 patients(15.17%),with in situ BIMA grafting in 290 patients(3.57%).For in situ BIMA group,the right internal mammary artery was used to revascularize the right coronary artery,while the left internal mammary artery was utilized for the left anterior descending artery.BIMA patients aged over 70 years(n=79)were compared with SIMA patients(n=79)using propensity score matching.Primary outcome was all-cause mortality at 30 days and 8 years.Secondary outcomes included length of hospital stay,incidence of postoperative major adverse cardiovascular and cerebrovascular events,sternal wound infection and the need for subsequent percutaneous revascularization.RESULTS There was no difference in immediate postoperative primary and secondary outcomes.Mean follow-up was 8.3±1.0 years with an 8-year freedom from death of 67.08%±1.1%in the BIMA group versus 58.22%±0.9%in the SIMA group(P<0.05).CONCLUSIONS BIMAs as in situ grafts can be successfully used in CABG for patients aged 70 years and older.Consequently,the refined techniques for constructing internal mammary artery grafts used in this study challenge traditionally accepted limitations regarding the use of BIMAs.
文摘Objective: To clarify the role of the “Three Threes” method in clinical teaching of internal jugular vein puncture and explore improvements in teaching methods. Methods: A doctor was assigned to the induction room of the Second Affiliated Hospital of Naval Medical University (Shanghai Changzheng Hospital) for two months. The time required for catheterization, the first puncture success rate, and occurrence of puncture-related complications were compared before and after learning the “Three Threes” method. Results: Using the “Three Threes” method reduced the catheterization time by 43%, increased the first puncture success rate by 17%, and led to fewer puncture-related complications. Conclusion: The application of the “Three Threes” method not only improves the success rate of internal jugular vein puncture but also reduces complications, making it easier for students to master the technique.
基金supported by the National Natural Science Foundation of China(Grant Nos.92252202,92152301,12293000,12293002,12302320,and 12388101)the Fundamental Research Funds for the Central Universities.
文摘Convection driven by a spatially non-uniform internal heat source between two horizontal isothermal walls is studied by theoretical analysis and numerical simulation,in order to explore the bounds of the temperature and the vertical heat flux.Specifically,the rigorous lower bound of the weighted average temperature<QT>is derived analytically,by decomposing the temperature field into a background profile and a fluctuation part.This bound obtained for the first time to consider non-uniform heat sources is found to be compatible with the existing bound obtained in uniform internal heat convection.Of physical importance,an analytical relationship is derived as an inequality connecting<QT>and the average vertical heat flux<wT>,by employing the average heat flux on the bottom wall(qb)as an intermediary variable.It clarifies the intrinsic relation between the lower bound of<QT>and the upper bound of<wT>,namely,these two bounds are essentially equivalent providing an easy way to obtain one from another.Furthermore,the analytical bounds are extensively demonstrated through a comprehensive series of direct numerical simulations.
基金financially supported by the National Natural Science Foundation of China(Grant No.41790432)Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDA20030301)。
文摘Internal erosion occurs when fine particles escape from the soil driven by seepage flow,which is considered to be the crucial factor causing the failure of earth structures filled with gravelly soil.The objective of this paper is to suggest an appropriate method to assess internal erosion potential of gravelly soil.By analyzing the sensitivity of soil material to internal erosion,the variable(Dc15/df85)max and the content of coarse particles(Pc)are selected as the evaluation indexes(Dc15 and df85 are the diameters of 15%mass passing in the coarse component and 85%mass passing in the fine component,respectively).A series of gravelly soils with different particle size distributions are tested for internal erosion by the self-made permeameter.Based on the test results,an evaluation method for the internal erosion of gravelly soil is proposed.Gravelly soil is prone to internal erosion when 60%≤Pc<95%and(Dc15/df85)max≥9.5.The proposed method shows good accuracy in evaluating the internal erosion of 36 soil samples from other studies,which confirms the reliability of the method.The proposed method makes it possible to accurately assess internal erosion of gravelly soil,and an alternative method is provided for engineers to determine whether there is a risk of internal erosion in earth structures consisting of gravelly soil.
文摘A corrosion defect is recognized as one of the most severe phenomena for high-pressure pipelines,especially those served for a long time.Finite-element method and empirical formulas are thereby used for the strength prediction of such pipes with corrosion.However,it is time-consuming for finite-element method and there is a limited application range by using empirical formulas.In order to improve the prediction of strength,this paper investigates the burst pressure of line pipelines with a single corrosion defect subjected to internal pressure based on data-driven methods.Three supervised ML(machine learning)algorithms,including the ANN(artificial neural network),the SVM(support vector machine)and the LR(linear regression),are deployed to train models based on experimental data.Data analysis is first conducted to determine proper pipe features for training.Hyperparameter tuning to control the learning process is then performed to fit the best strength models for corroded pipelines.Among all the proposed data-driven models,the ANN model with three neural layers has the highest training accuracy,but also presents the largest variance.The SVM model provides both high training accuracy and high validation accuracy.The LR model has the best performance in terms of generalization ability.These models can be served as surrogate models by transfer learning with new coming data in future research,facilitating a sustainable and intelligent decision-making of corroded pipelines.
文摘The deviations of trajectory and attitude angle for internal store separation are evaluated by two wind tunnel test methods.One is the Freedrop Test(FDT),which is known as unsteady and time-dependent method of scaled model.The other is the Captive Trajectory System(CTS)test,which is usually regarded as a quasi-steady and time-averaged test technology.The result shows that there is a streamwise adverse pressure gradient on the cavity resulting in a nose-up pitching moment coefficient(>0)acting on the store model.When the initial pitch angular velocity is 0,the store exits the shear-layer with a nose-up pitch attitude causing the store to climb back towards and collide with the aircraft.However,the store passes through the shear-layer into the freestream with a nose-down pitch,which causes a successful separation event when the initial pitch angular velocity<0.The pitch angle obtained by unsteady test method is different from that by quasisteady test method.The time-dependent test includes the aerodynamic force induced by pitch angular velocity whereas the time-averaged method(CTS)cannot reflect the effect of unsteady aerodynamic force.The deviation of vertical displacement is not obvious for FDT and CTS test since the store has an initial vertical velocity,which is dominant for the vertical displacement.This means that the highly unsteady flow can create unpredictability in aerodynamic pitching moment of the store,which can lead to the deviation of pitch angle for internal store separation.
基金Funded by National Scholastic Athletics Foundotion(NSAF)(No.U1330113)National Natural Science Foundation of China(No.81271953)
文摘Wafer curvature method has been applied to determine the internal stress in the films using Stoney＇s equation.During the film deposition,the wafer fixation on the sample holder will restrict the deformation of the rectangle-shaped wafer,which may result in the stress datum difference along length and width direction.In this paper,the effect of wafer size and the wafer fixation on the TiN film internal stress measured by wafer curvature method was discussed.The rectangle-shaped wafers with different length/width ratios（L/W=1：1,2：1,3：1 and 4：1） were fixed as a cantilever beam.After the TiN films deposition,the profiles of the film/wafer were measured using a stylus profilometer and then the internal stress was calculated using the Stoney equation in the film.The results showed that the fixed end of the wafers limited to some degree the curvature of the wafers along the width direction.For film internal stress measured by wafer curvature method,the wafer profile should be scanned along the length direction and the scan distance should be greater than or equal to half of wafer length.When the length/width ratio of the wafer reached 3：1,the wafer curvature and the calculated stress were basically the same at different positions along the length direction.For film internal stress measured by wafer curvature method,it was recommended that the length/width ratio of wafer should be considered to be greater than or equal to 3：1,and the deformed profile was scanned along the length direction.
文摘Objective:To observe and analyze the application of the bedside rhetorical teaching method in teaching nursing interns.Methods:A total of 64 nursing interns in the gastroenterology department of our hospital from July 2022 to May 2023 were randomly divided into two groups,32 cases in the control group and 32 cases in the intervention group.The control group was given conventional teaching methods,and the intervention group was given the bedside rhetorical teaching method on the basis of the conventional teaching.The differences in the methods of teaching between the two groups were compared after the end of the internship,and there was a statistically significant difference with P<0.05.Results:The scores of the interns in the intervention group were significantly better than those of the control group in theoretical knowledge,communication skills,and case analysis items(P<0.05).Conclusion:The bedside rhetorical teaching method transforms classroom education into bedside teaching,which enables the interns to apply the theoretical knowledge to clinical practice,and has a higher improvement in the three aspects of disease knowledge,communication skills,and case analysis,cultivates the interns’comprehensive clinical skills,and lays a good foundation for the future entry into the nursing field.
文摘Laser ablation coupled with inductively coupled plasma-mass spectrometry (LA-ICP-MS) calibration was conducted with multiple spot analyses on eleven intact rock samples using both an internal standard (IS) method and a modified constant-sum (MCS) method. Methods were then compared for reported bulk elemental composition of the rocks. The MCS method was based on the sum of eight major elements, which is spatially more stable than one single major ele-ment as used in the IS method, and is quite constant among different rock samples. Calibrations were performed with standard reference materials NIST SRM 610, 612, 614, and 616. Little difference was found between using a single standard and a set of standards, because of the good linearity shown by the reference materials. Comparison of the two calibration methods shows that the MCS method produced better and more stable results than the IS method for heterogeneous samples. With the MCS method, approximately 94% to 95% of the total measurements are within the range of ±100% relative deviation, compared with 82% to 86% with the IS method. The IS method resulted insubstantial overestimations for some rock samples (e.g., 648% for Basalt BCR-2 using NIST SRM 610 as the calibration standard), while the largest deviation with the MCS method was 216% for U in Eagle Ford shale #80 sample. For Quartz latite QLO-1, a relative homogeneous sample, the IS method generated slightly better results than the MCS method. Regardless of method, spatially heterogeneous distribution of elements in the intact rock at the scale of the laser spot is considered to be the main reason for the large relative deviations seen in our work compared to published results.
文摘The internal standard (IS) method is the best method for the analysis of samples, as it is independent of errors in injection volume, changes in sample volumes, and changes in sensitivity of the detector, etc. Use of an internal standard allows for the correction of losses due to sample clean-up of complex samples. An ideal IS is a compound that has properties very similar to, and that behaves as the compounds to be analysed. Ideally, only in the last step of analysis (HPLC), the IS should be well separated from the compounds of the mixture to be analysed. After testing several existing compounds with negative results, we decided to synthesise the 19-O-β-D-galactopyranosyl-13-O-β-D-glucopyranosyl-steviol as IS. This is the 19-galactosyl ester of steviolmonoside (13-O-β-D-glucopyranosyl-steviol). The IS was made according to published methods. Steviolmonoside (SM) was made from purified commercial rubusoside (Rub) by refluxing it in 10% KOH for 2 h. SM was precipitated and crystallized from MeOH. The hydroxyls of the glucose unit of SM were protected by acetylation. The acetylated SM was crystallized from acetone and dissolved in 1,2-dichloroethane. Then Ag2CO3 on Celite and tetra-acetylated galactopyranosyl bromide were added and the mixture was refluxed for 2 h. After cooling, BaO in MeOH was added to remove the acetyl groups. The 1,2-dichloroethane fraction was then extracted three times with equal volumes of water and the water fraction containing the IS was further purified on a C18 flash chromatography column. Traces of unreacted SM were removed by preparative HPLC on an Alltima C18 column (250 mm × 22 mm, particle size 10 μm) with AcCN:water (35:65, 20 ml/min). Detection was at 210 nm (KNAUER, “Smartline” UV detector 2500). The collected IS fraction from the HPLC was completely dried. Mixtures of steviol glycosides (SVglys) containing IS could be purified over SPE cartridges without change of the SVgly over IS ratio. The calibration curves for rebaudioside A (RebA) and stevioside (ST) were linear between 0.012 and 0.95 and between 0.013 and 1.13 mM for RebA and ST, respectively. The accuracy was checked by the standard addition method. It was concluded that the IS method gives an excellent precision and accuracy.
文摘[Objective]This study was to establish a rapid,specific and simple method for quantitative determination of tetrachlorantraniliprole by 1H NMR.[Method]1H NMR spectroscopy was acquired with deuterium DMSO as the solvent and maleic acid as internal standard under the conditions of temperature 25℃,pulses width 8.0μs,delay time 5 s,and scanning times 8.[Result]The hydrogen proton peaks of tetrachlorantraniliprole(δ=10.55)and maleic acid(δ=6.27)were taken as quantitative peaks.The peak area ratio y(As/Ar)and mass ratio x(ms/mr)were linearly regressed,and the correlation coefficient was 0.9999.The RSD value of repeatability test was 0.38%,and the RSD value of stability test was 0.77%.The content of tetrachlorantraniliprole was determined as 99.6%.[Conclusion]1H NMR spectroscopy can be used for quantitative determination of tetrachlorantraniliprole without standard reference,which is rapid,accurate and simple.
基金supported by the National Natural Science Foundation of China (No. 21377065)the 863 National High-Tech Research and Development Program (No. 2014AA06A506)
文摘Mercury and its organic compounds have been of severe concern worldwide due to their damage to the ecosystem and human health. The development of effective and affordable technology to monitor and signal the presence of bioavailable mercury is an urgent need.The Mer gene is a mercury-responsive resistant gene, and a mercury-sensing recombinant luminescent bacterium using the Mer gene was constructed in this study. The mer operon from marine Pseudomonas putida strain SP1 was amplified and fused with prompterless lux CDABE in the p UCD615 plasmid within Escherichia coli cells, resulting in p THE30–E. coli.The recombinant strain showed high sensitivity and specificity. The detection limit of Hg^2＋was 5 nmol/L, and distinct luminescence could be detected in 30 min. Cd^2＋, Cu^2＋, Zn^2＋, Ca^2＋,Pb^2＋, Mg^2＋, Mn^2＋, and Al^3＋did not interfere with the detection over a range of 10-5–1 m M.Application of recombinant luminescent bacteria testing in environmental samples has been a controversial issue： especially for metal-sensing recombinant strains, false negatives caused by high cytotoxicity are one of the most important issues when applying recombinant luminescent bacteria in biomonitoring of heavy metals. In this study, by establishing an internal standard approach, the false negative problem was overcome;furthermore, the method can also help to estimate the suspected mercury concentration,which ensures high detection sensitivity of bioavailable Hg2＋.
文摘Uranium carbide kernels is one special fuel materials for the High-Temperature Gas-cooled Reactor[1], which can improve nuclear fuel’s efficiency, longevity, and safety. In the fabrication process, there are many factors affect the quality of the kernels, such as subsequent ageing, HMTA/uranium mole ratio, gelation forming temperature, washing step, heating rate of the calcine and sinter step, one important step is the dispersing carbon into the solution stock of HMTA and urea[2;3].
基金the Deanship of Research and Graduate Studies at King Khalid University for funding this work through Large Research Project under grant number RGP2/308/46。
文摘Fins are extensively utilized in heat exchangers and various industrial applications as they are lightweight and can benefit in various systems,including electronic cooling devices and automotive components,owing to their adaptable design.Furthermore,spine fins are introduced to improve performance in applications such as automotive radiators.They can be shaped in different ways and constructed from a collection of materials.Inspired by this,the present model examines the effects of internal heat generation and radiation-convection on the thermal distribution in a wetted convex-shaped spine fin.Using dimensionless terms,the proposed fin model involving a governing nonlinear ordinary differential equation(ODE)is transformed into a dimensionless form.The study uses the operational matrix with the Charlier polynomial collocation method(OMCCM)to ensure precise and computationally efficient numerical solutions for the dimensionless equation.In order to aid in the analysis of thermal performance,the importance of major parameters on the temperature profile is graphically illustrated.The main outcome of the study reveals that as the radiation-conductive,wet,and convective-conductive parameters increase,the heat transfer rate progressively improves.Conversely,the ambient temperature and internal heat generation parameters show an inverse relationship.
文摘In this paper, based on the idea of finite element method, the initial parametric method in bending, problem of a beam is extended to analyse the bar-system structure by employing Dirac function and llcavisidc step function.Then a new method for analysing the internal forces and deformations of bar-system structure in space is suggested by improving the mixed method in statically indeterminate structure.The inferred process and obtained answer will be more succinct and accurate when the problem of internal forces and deformations of bar-system structure is analysed by using the new method provided in this paper.
文摘In this study,the impacts of internal heat generation on heat transfer enhancement of porous fin is theoretical investigated using differential transform method.The parametric studies reveal that porosity enhances the fin heat dissipating capacity but the internal heat generation decreases the heat enhancement capacity of extended surface.Also,it is established that when the internal heat parameter increases to some certain values,some negative effects are recorded where the fin stores heat rather than dissipating it.This scenario defeats the prime purpose of the cooling fin.Additionally,it is established in the present study that the limiting value of porosity parameter for thermal stability for the passive device increases as internal heat parameter increases.This shows that although the internal heat parameter can help assist higher range and value of thermal stability of the fin,it produces negative effect which greatly defeats the ultimate purpose of the fin.The results in the work will help in fin design for industrial applications where internal heat generation is involved.
文摘The hatches for inspecting are usually designed with elliptical holes in airplane structures, so computation of the stress intensity factor of three dimensional crack at elliptical holes is pivotal for damage tolerance analysis of these structures. In this paper, weight function is derived for a two dimensional through cracks at elliptical holes by applying a compounding method. Stress intensity factor formulas for an internal surface semi-elliptical crack in elliptical holes are obtained wing the three dimensional weight function method. Stress intensity factors for an internal surface semi-elliptical crack in elliptical holes under remote tension are computed. At the same time, research on how radius of curvature for elliptical holes affect stress intensity factors was conducted. Stress intensity factors decrease when radius of curvature increases. Some results and conclusions which are of practical value are given.
文摘Objective: to explore the application effect of situational teaching method in the overall nursing of internal medicine. Methods: select our hospital in January 2019 to January 2021 accepted 196 practice nurses as research object, through the random group, divided into two groups, each group 98, a group set into group A, the conventional teaching method, another group set into group B, in routine teaching at the same time, the implementation of situational teaching method, compare the two groups of practice nurses theory assessment results and satisfaction. Results: 95.92% of the theoretical scores in group B was higher than 82.65% in Group A;94.90% of trainee nurses in Group B were higher than 80.61% in Group A;Total score of practice nurses (95.37 ± 105.58) was higher than that of (88.22 ± 10.26) in Group B. Conclusion: when training the internal practice nurses, the situational teaching method has good application effect, which can not only improve the mastery of relevant theoretical knowledge, but also obtain the higher satisfaction of practice nurses and improve the views of practice nurses on their own work, which can be promoted on a large scale.
文摘There is an old saying,“Give a man a fish,and he will eat for a day.Teach a man to fish,and he will eat for the rest of his life.”In clinical teaching,students should not only be taught about diseases,but their intelligence should also be cultivated,along with their analytical,comprehension,and independent learning skills.The ability to solve problems enables students to think independently and acquire knowledge.This is known as the heuristic method of teaching.In this study,we mainly analyze the application value of the heuristic method in the clinical teaching of internal medicine.
