BACKGROUND Hypertensive cerebral hemorrhage(HICH)is the rupture and bleeding of vessels of the cerebral parenchyma caused by continuously elevated or violently fluctuating blood pressure.The condition is characterized...BACKGROUND Hypertensive cerebral hemorrhage(HICH)is the rupture and bleeding of vessels of the cerebral parenchyma caused by continuously elevated or violently fluctuating blood pressure.The condition is characterized by high disability and high mortality.Hematoma formation and resulting space-occupying effects following intracerebral hemorrhage are among the key causes of impaired neurological function and disability.Consequently,minimally invasive clearance of the hematoma is undertaken for the treatment of HICH because it can effectively relieve intracranial hypertension.Therefore,special attention should be given to the quality of medical and nursing interventions in the convalescent period after minimally invasive hematoma clearance.AIM The study aim was to determine the value of intensive intervention,including doctors,nurses,and patient families,for the prevention of rebleeding in elderly patients with HICH during the first hospitalization for rehabilitation after the ictal event METHODS A total of 150 elderly HICH patients with minimally invasive hematoma evacuation in our hospital between May 2018 and May 2020 were selected and equally divided into two groups of 75 each by their planned intervention.The control group was given conventional nursing intervention and the observation group was given tripartite intensive intervention.The length of hospital stay,cost,complication rate,satisfaction rate,and rebleeding rate during hospitalization were recorded.Changes in cerebral blood flow indicators were recorded in both groups.Changes in the National Institutes of Health Stroke Scale(NIHSS)score,quality of life index(QLI)score,and health behavior score were evaluated at the National Institutes of Health.RESULTS Duration of hospitalization was shorter in the in the observation group than in the control group,the hospitalization cost was less than in the control group,and the rate of rebleeding during hospitalization was lower than in the control group(all P<0.05).There were no significant differences between the two groups before treatment(all P>0.05).The mean flow rate(Qmean)and mean velocity(Vmean)of the two groups increased(P<0.05),and the dynamic resistance and peripheral resistance decreased(P<0.05).The Qmean and Vmean in the intervention group were higher than those in the control group(P<0.05).Moreover,the dynamic resistance and peripheral resistance of the blood vessels were also lower in the intervention group than in the control group(P<0.05).The difference in health behavior scores between the two groups before treatment was not significant(P>0.05).In both groups,the scores for healthy behaviors such as emotion control,medication adherence,dietary management,exercise management,and selfmonitoring were higher after than before treatment(P<0.05),and the scores of healthy behaviors in the intervention group were higher than those in the control group(P<0.05).There was no significant difference in the NIHSS and QLI scores between the two groups before treatment(P>0.05).The QLI scores of the two groups increased(P<0.05),and the NIHSS scores decreased(P<0.05).The QLI scores of the intervention group were higher than those of the control group(P<0.05),and the NIHSS score was correspondingly lower than that of the control group(P<0.05).The incidence of respiratory infections,pressure sores,central hyperpyrexia,and deep venous thrombosis was lower in the intervention group than in the control group.Accordingly,the satisfaction rate was higher in the treatment group than that in the control group(P<0.05).CONCLUSION Intensive intervention by doctors,nurses,and families of elderly patients with HICH reduced the rate of rebleeding during hospitalization.It also reduced the incidence of complications,promoted rehabilitation,improved the quality of life,and enhanced nerve function.Additionally,it improved satisfaction and promoted healthy behaviors.展开更多
BACKGROUND Epilepsy is a nervous system disease characterized by recurrent attacks,a long disease course,and an unfavorable prognosis.It is associated with an enduring therapeutic process,and finding a cure has been d...BACKGROUND Epilepsy is a nervous system disease characterized by recurrent attacks,a long disease course,and an unfavorable prognosis.It is associated with an enduring therapeutic process,and finding a cure has been difficult.Patients with epilepsy are predisposed to adverse moods,such as resistance,anxiety,nervousness,and anxiety,which compromise treatment compliance and overall efficacy.AIM To explored the influence of intensive psychological intervention on treatment compliance,psychological status,and quality of life(QOL)of patients with epilepsy.METHODS The clinical data of 105 patients with epilepsy admitted between December 2019 and July 2023 were retrospectively analyzed,including those of 50 patients who underwent routine intervention(control group)and 55 who underwent intensive psychological intervention(research group).Treatment compliance,psychological status based on the Self-Rating Anxiety Scale(SAS)and Depression Scale Self-Rating Depression Scale(SDS)scores,hope level assessed using the Herth Hope Scale(HHS),psychological resilience evaluated using the Psychological Resilience Scale,and QOL determined using the QOL in Epilepsy-31 Inventory(QOLIE-31)were comparatively analyzed.RESULTS Treatment compliance in the research group was 85.5%,which is significantly better than the 68.0%of the control group.No notable intergroup differences in preinterventional SAS and SDS scores were identified(P>0.05);however,after the intervention,the SAS and SDS scores decreased significantly in the two groups,especially in the research group(P<0.05).The two groups also exhibited no significant differences in preinterventional HHS,Connor-Davidson Resilience Scale(CD-RISC),and QOLIE-31 scores(P>0.05).After 6 months of intervention,the research group showed evidently higher HHS,CD-RISC,tenacity,optimism,strength,and QOLIE-31 scores(P<0.05).CONCLUSION Intensive psychological intervention enhances treatment compliance,psychological status,and QOL of patients with epilepsy.展开更多
Objective: to observe the effect of intensive cognitive intervention on treatment compliance, self-management and lifestyle in hospitalized elderly hypertensive patients. Methods: from January 2021 to January 2022, me...Objective: to observe the effect of intensive cognitive intervention on treatment compliance, self-management and lifestyle in hospitalized elderly hypertensive patients. Methods: from January 2021 to January 2022, members of this research group collected 120 elderly hypertensive patients in hospital in the fourth department of general internal medicine, First Affiliated Hospital of Xinjiang Medical University, numbered all patients, and then divided them into controlgroup and observation group, and each group included 60 cases. The control group received routine intervention, and the observation group received intensive cognitive intervention. Comparison of treatment adheres to self-management scores, and lifestyle. Results: after nursing intervention of all patients, the comparative analysis of various observation indicators showed that the treatment compliance of the observation group was higher than that of the control group (95.5% vs 81.7%), and the salt intake score in the self-management score (8.27±0.91 vs 7.51± 0.88 points), doctor-patient communication score (8.02±0.95 vs 7.01±0.87 points), cognitive symptom management score (9.03±0.67 vs 8.14±0.91 points), endurance exercise score (8.98±0.82 vs 7.84±0.83 points) and the scores of physical exercise (8.83±0.66 vs 8.02±0.71) were higher than those of the control group, and the proportion of reasonable diet in lifestyle (90.0% vs 73.3%), the proportion of smoking cessation and alcohol restriction (95.0% vs 81.7%) and the proportion of reasonable exercise ( 86.7% vs 70.0%) were higher than those of the control group in hospitalized elderly hypertensive patients, with statistical difference (Pall <0.05). Conclusion: intensive cognitive intervention can improve the treatment compliance and self-management level of hospitalized elderly hypertensive patients, and promote the patients to establish a healthy lifestyle.展开更多
Objective: to analyze the influence of intensive nursing intervention on the prevention of unplanned extubation of ICU patients. Methods: 72 inpatients in ICU from September 2020 to October 2021 were selected as the r...Objective: to analyze the influence of intensive nursing intervention on the prevention of unplanned extubation of ICU patients. Methods: 72 inpatients in ICU from September 2020 to October 2021 were selected as the research object, and they were randomly divided into the observation group and the control group, with 36 cases in each group. The control group was given routine nursing care, and the observation group was given intensive nursing intervention, and the relevant indicators were compared. Results: the scores of nursing satisfaction in the observation group were higher than those in the control group (P0.05);The incidence of unplanned extubation in the observation group was significantly lower than that in the control group (8.33% vs 25.00%) (P0.05);The time spent in ICU in the observation group was significantly shorter than that in the control group (P0.05);The sleep time in the observation group was significantly higher than that in the control group (P0.05). Conclusion: intensive nursing intervention can effectively prevent unplanned extubation of ICU patients, prolong their sleep time and shorten their stay in ICU.展开更多
Background A five-year follow-up study of intensive multifactorial intervention was undertaken to assess the changes of circulating serum amyloid A （SAA） levels and the incidence of atherosclerosis （AS） in patient...Background A five-year follow-up study of intensive multifactorial intervention was undertaken to assess the changes of circulating serum amyloid A （SAA） levels and the incidence of atherosclerosis （AS） in patients with short-duration type 2 diabetes mellitus （T2DM） without macroangiopathy, and whether intensive multifactorial intervention could prevent or at least postpone the occurence of macroangiopathy. Methods Among 150 patients with short-duration T2DM, 75 were assigned to receive conventional outpatient treatment （conventional group） and the others underwent intensive multifactorial integrated therapy targeting hyperglycemia, hypertension, dyslipidemia and received aspirin simultaneously （intensive group）. Results Plasma SAA levels were higher in diabetic patients than those in healthy control subjects, and decreased obviously after intensive multifactorial intervention. The levels of SAA were positively correlated with body mass index （BMI）, waist hip ratio （WHR）, triglyceride （TG）, high sensitive C-reactive protein （hs-CRP） and common carotid intima-media thickness （CC-IMT）. The standard-reaching rates of glycemia, blood pressure and lipidemia were significantly higher in intensive group than those of conventional group. The incidence of macroangiopathy decreased by 58.96% in intensive group compared with conventional group. Conclusions Intensive multifactorial intervention may significantly reduce the SAA levels and prevent the occurrence of AS in short-duration patients with T2DM. SAA might be one of the risk factors of T2DM combined with AS.展开更多
Introduction:This study reports a confirmed case of human rabies diagnosed through metagenomic nextgeneration sequencing(mNGS).The patient was a 22-year-old female who developed symptoms 3 months after sustaining a sc...Introduction:This study reports a confirmed case of human rabies diagnosed through metagenomic nextgeneration sequencing(mNGS).The patient was a 22-year-old female who developed symptoms 3 months after sustaining a scratch on the upper lip from a domesticated dog,without receiving postexposure prophylaxis(PEP).She initially presented with urinary symptoms and was misdiagnosed with a urinary tract infection.Neurological symptoms subsequently emerged,prompting intensive life support interventions including mechanical ventilation,recombinant human interferon-α2b,ribavirin,norepinephrine,venoarterial extracorporeal membrane oxygenation(VAECMO),and continuous renal replacement therapy.Methods:Clinical data were collected from hospital records,including exposure history,symptoms,treatments,and outcomes.Saliva specimens were tested by reverse transcription polymerase chain reaction(RTPCR)and mNGS.Sequencing data were processed by standard bioinformatics pipelines,and phylogenetic analysis was performed with MAFFT alignment and IQ-TREE maximum-likelihood reconstruction.Results:Rabies virus infection was confirmed through reverse transcription polymerase chain reaction(RTPCR)and mNGS analysis of saliva samples.The detected strain,JSTZ190314,represents the first documented case of this genotype in Guangxi,China.Despite initial stabilization with ECMO support,the patient’s neurological condition deteriorated progressively,leading to brain death 28 days after neurological onset(34 days from initial urinary symptoms).Conclusion:mNGS proves invaluable as a diagnostic tool for atypical rabies presentations.Enhancing early clinical recognition capabilities,ensuring timely and standardized PEP implementation,and strengthening regional viral strain surveillance represent critical components for effective rabies prevention and control strategies.展开更多
文摘BACKGROUND Hypertensive cerebral hemorrhage(HICH)is the rupture and bleeding of vessels of the cerebral parenchyma caused by continuously elevated or violently fluctuating blood pressure.The condition is characterized by high disability and high mortality.Hematoma formation and resulting space-occupying effects following intracerebral hemorrhage are among the key causes of impaired neurological function and disability.Consequently,minimally invasive clearance of the hematoma is undertaken for the treatment of HICH because it can effectively relieve intracranial hypertension.Therefore,special attention should be given to the quality of medical and nursing interventions in the convalescent period after minimally invasive hematoma clearance.AIM The study aim was to determine the value of intensive intervention,including doctors,nurses,and patient families,for the prevention of rebleeding in elderly patients with HICH during the first hospitalization for rehabilitation after the ictal event METHODS A total of 150 elderly HICH patients with minimally invasive hematoma evacuation in our hospital between May 2018 and May 2020 were selected and equally divided into two groups of 75 each by their planned intervention.The control group was given conventional nursing intervention and the observation group was given tripartite intensive intervention.The length of hospital stay,cost,complication rate,satisfaction rate,and rebleeding rate during hospitalization were recorded.Changes in cerebral blood flow indicators were recorded in both groups.Changes in the National Institutes of Health Stroke Scale(NIHSS)score,quality of life index(QLI)score,and health behavior score were evaluated at the National Institutes of Health.RESULTS Duration of hospitalization was shorter in the in the observation group than in the control group,the hospitalization cost was less than in the control group,and the rate of rebleeding during hospitalization was lower than in the control group(all P<0.05).There were no significant differences between the two groups before treatment(all P>0.05).The mean flow rate(Qmean)and mean velocity(Vmean)of the two groups increased(P<0.05),and the dynamic resistance and peripheral resistance decreased(P<0.05).The Qmean and Vmean in the intervention group were higher than those in the control group(P<0.05).Moreover,the dynamic resistance and peripheral resistance of the blood vessels were also lower in the intervention group than in the control group(P<0.05).The difference in health behavior scores between the two groups before treatment was not significant(P>0.05).In both groups,the scores for healthy behaviors such as emotion control,medication adherence,dietary management,exercise management,and selfmonitoring were higher after than before treatment(P<0.05),and the scores of healthy behaviors in the intervention group were higher than those in the control group(P<0.05).There was no significant difference in the NIHSS and QLI scores between the two groups before treatment(P>0.05).The QLI scores of the two groups increased(P<0.05),and the NIHSS scores decreased(P<0.05).The QLI scores of the intervention group were higher than those of the control group(P<0.05),and the NIHSS score was correspondingly lower than that of the control group(P<0.05).The incidence of respiratory infections,pressure sores,central hyperpyrexia,and deep venous thrombosis was lower in the intervention group than in the control group.Accordingly,the satisfaction rate was higher in the treatment group than that in the control group(P<0.05).CONCLUSION Intensive intervention by doctors,nurses,and families of elderly patients with HICH reduced the rate of rebleeding during hospitalization.It also reduced the incidence of complications,promoted rehabilitation,improved the quality of life,and enhanced nerve function.Additionally,it improved satisfaction and promoted healthy behaviors.
文摘BACKGROUND Epilepsy is a nervous system disease characterized by recurrent attacks,a long disease course,and an unfavorable prognosis.It is associated with an enduring therapeutic process,and finding a cure has been difficult.Patients with epilepsy are predisposed to adverse moods,such as resistance,anxiety,nervousness,and anxiety,which compromise treatment compliance and overall efficacy.AIM To explored the influence of intensive psychological intervention on treatment compliance,psychological status,and quality of life(QOL)of patients with epilepsy.METHODS The clinical data of 105 patients with epilepsy admitted between December 2019 and July 2023 were retrospectively analyzed,including those of 50 patients who underwent routine intervention(control group)and 55 who underwent intensive psychological intervention(research group).Treatment compliance,psychological status based on the Self-Rating Anxiety Scale(SAS)and Depression Scale Self-Rating Depression Scale(SDS)scores,hope level assessed using the Herth Hope Scale(HHS),psychological resilience evaluated using the Psychological Resilience Scale,and QOL determined using the QOL in Epilepsy-31 Inventory(QOLIE-31)were comparatively analyzed.RESULTS Treatment compliance in the research group was 85.5%,which is significantly better than the 68.0%of the control group.No notable intergroup differences in preinterventional SAS and SDS scores were identified(P>0.05);however,after the intervention,the SAS and SDS scores decreased significantly in the two groups,especially in the research group(P<0.05).The two groups also exhibited no significant differences in preinterventional HHS,Connor-Davidson Resilience Scale(CD-RISC),and QOLIE-31 scores(P>0.05).After 6 months of intervention,the research group showed evidently higher HHS,CD-RISC,tenacity,optimism,strength,and QOLIE-31 scores(P<0.05).CONCLUSION Intensive psychological intervention enhances treatment compliance,psychological status,and QOL of patients with epilepsy.
文摘Objective: to observe the effect of intensive cognitive intervention on treatment compliance, self-management and lifestyle in hospitalized elderly hypertensive patients. Methods: from January 2021 to January 2022, members of this research group collected 120 elderly hypertensive patients in hospital in the fourth department of general internal medicine, First Affiliated Hospital of Xinjiang Medical University, numbered all patients, and then divided them into controlgroup and observation group, and each group included 60 cases. The control group received routine intervention, and the observation group received intensive cognitive intervention. Comparison of treatment adheres to self-management scores, and lifestyle. Results: after nursing intervention of all patients, the comparative analysis of various observation indicators showed that the treatment compliance of the observation group was higher than that of the control group (95.5% vs 81.7%), and the salt intake score in the self-management score (8.27±0.91 vs 7.51± 0.88 points), doctor-patient communication score (8.02±0.95 vs 7.01±0.87 points), cognitive symptom management score (9.03±0.67 vs 8.14±0.91 points), endurance exercise score (8.98±0.82 vs 7.84±0.83 points) and the scores of physical exercise (8.83±0.66 vs 8.02±0.71) were higher than those of the control group, and the proportion of reasonable diet in lifestyle (90.0% vs 73.3%), the proportion of smoking cessation and alcohol restriction (95.0% vs 81.7%) and the proportion of reasonable exercise ( 86.7% vs 70.0%) were higher than those of the control group in hospitalized elderly hypertensive patients, with statistical difference (Pall <0.05). Conclusion: intensive cognitive intervention can improve the treatment compliance and self-management level of hospitalized elderly hypertensive patients, and promote the patients to establish a healthy lifestyle.
文摘Objective: to analyze the influence of intensive nursing intervention on the prevention of unplanned extubation of ICU patients. Methods: 72 inpatients in ICU from September 2020 to October 2021 were selected as the research object, and they were randomly divided into the observation group and the control group, with 36 cases in each group. The control group was given routine nursing care, and the observation group was given intensive nursing intervention, and the relevant indicators were compared. Results: the scores of nursing satisfaction in the observation group were higher than those in the control group (P0.05);The incidence of unplanned extubation in the observation group was significantly lower than that in the control group (8.33% vs 25.00%) (P0.05);The time spent in ICU in the observation group was significantly shorter than that in the control group (P0.05);The sleep time in the observation group was significantly higher than that in the control group (P0.05). Conclusion: intensive nursing intervention can effectively prevent unplanned extubation of ICU patients, prolong their sleep time and shorten their stay in ICU.
文摘Background A five-year follow-up study of intensive multifactorial intervention was undertaken to assess the changes of circulating serum amyloid A （SAA） levels and the incidence of atherosclerosis （AS） in patients with short-duration type 2 diabetes mellitus （T2DM） without macroangiopathy, and whether intensive multifactorial intervention could prevent or at least postpone the occurence of macroangiopathy. Methods Among 150 patients with short-duration T2DM, 75 were assigned to receive conventional outpatient treatment （conventional group） and the others underwent intensive multifactorial integrated therapy targeting hyperglycemia, hypertension, dyslipidemia and received aspirin simultaneously （intensive group）. Results Plasma SAA levels were higher in diabetic patients than those in healthy control subjects, and decreased obviously after intensive multifactorial intervention. The levels of SAA were positively correlated with body mass index （BMI）, waist hip ratio （WHR）, triglyceride （TG）, high sensitive C-reactive protein （hs-CRP） and common carotid intima-media thickness （CC-IMT）. The standard-reaching rates of glycemia, blood pressure and lipidemia were significantly higher in intensive group than those of conventional group. The incidence of macroangiopathy decreased by 58.96% in intensive group compared with conventional group. Conclusions Intensive multifactorial intervention may significantly reduce the SAA levels and prevent the occurrence of AS in short-duration patients with T2DM. SAA might be one of the risk factors of T2DM combined with AS.
基金Supported by the Specific Research Project of Guangxi for Research Bases and Talents(AD22035052).
文摘Introduction:This study reports a confirmed case of human rabies diagnosed through metagenomic nextgeneration sequencing(mNGS).The patient was a 22-year-old female who developed symptoms 3 months after sustaining a scratch on the upper lip from a domesticated dog,without receiving postexposure prophylaxis(PEP).She initially presented with urinary symptoms and was misdiagnosed with a urinary tract infection.Neurological symptoms subsequently emerged,prompting intensive life support interventions including mechanical ventilation,recombinant human interferon-α2b,ribavirin,norepinephrine,venoarterial extracorporeal membrane oxygenation(VAECMO),and continuous renal replacement therapy.Methods:Clinical data were collected from hospital records,including exposure history,symptoms,treatments,and outcomes.Saliva specimens were tested by reverse transcription polymerase chain reaction(RTPCR)and mNGS.Sequencing data were processed by standard bioinformatics pipelines,and phylogenetic analysis was performed with MAFFT alignment and IQ-TREE maximum-likelihood reconstruction.Results:Rabies virus infection was confirmed through reverse transcription polymerase chain reaction(RTPCR)and mNGS analysis of saliva samples.The detected strain,JSTZ190314,represents the first documented case of this genotype in Guangxi,China.Despite initial stabilization with ECMO support,the patient’s neurological condition deteriorated progressively,leading to brain death 28 days after neurological onset(34 days from initial urinary symptoms).Conclusion:mNGS proves invaluable as a diagnostic tool for atypical rabies presentations.Enhancing early clinical recognition capabilities,ensuring timely and standardized PEP implementation,and strengthening regional viral strain surveillance represent critical components for effective rabies prevention and control strategies.
