BACKGROUND Insulin pump therapy is a real breakthrough in managing diabetes Mellitus,particularly in children. It can deliver a tiny amount of insulin and decreases the need for frequent needle injections. It also hel...BACKGROUND Insulin pump therapy is a real breakthrough in managing diabetes Mellitus,particularly in children. It can deliver a tiny amount of insulin and decreases the need for frequent needle injections. It also helps to maintain adequate and optimal glycemic control to reduce the risk of metabolic derangements in different tissues.Children are suitable candidates for pump therapy as they need a more freestyle and proper metabolic control to ensure adequate growth and development.Therefore, children and their caregivers should have proper education and training and understand the proper use of insulin pumps to achieve successful pump therapy. The pump therapy continuously improves to enhance its performance and increase its simulation of the human pancreas. Nonetheless, there is yet a long way to reach the desired goal.AIM To review discusses the history of pump development, its indications, types, proper use, special conditions that may enface the children and their families while using the pump, its general care,and its advantages and disadvantages.METHODS We conducted comprehensive literature searches of electronic databases until June 30, 2022,related to pump therapy in children and published in the English language.RESULTS We included 118 articles concerned with insulin pumps, 61 were reviews, systemic reviews, and meta-analyses, 47 were primary research studies with strong design, and ten were guidelines.CONCLUSION The insulin pump provides fewer needles and can provide very tiny insulin doses, a convenient and more flexible way to modify the needed insulin physiologically, like the human pancreas, and can offer adequate and optimal glycemic control to reduce the risk of metabolic derangements in different tissues.展开更多
To analyze the application effect of insulin pump in the treatment of diabetes. Methods: 100 cases of diabetic patients in our hospital were selected and randomly divided into the control group and the observation gro...To analyze the application effect of insulin pump in the treatment of diabetes. Methods: 100 cases of diabetic patients in our hospital were selected and randomly divided into the control group and the observation group. The control group received routine insulin therapy and the observation group received insulin pump therapy. The therapeutic effects of the two groups of patients were counted. Results: the therapeutic effect of the observation group was better than that of the control group (P<0.05). Conclusion: in the whole course of treatment for diabetic patients, a relatively safe way should be used to help patients control blood sugar. Insulin pump is one of the emerging clinical treatment methods. In the process of reasonable clinical control of blood sugar, the patient's blood sugar situation can be analyzed so as to help patients control blood sugar, which is welcomed by patients in clinic. The dosage of insulin pump used by patients should also be systematically explored, so as to provide patients with high-quality treatment services, improve patients' blood sugar, and avoid abnormal conditions of patients. It is recommended to promote it in a wide range of clinical practice.展开更多
Type 2 diabetes mellitus (T2MD) is a common chronic endocrine disease, if blood sugar isn't well controlled, except for hyperglycemia, also prone to metabolic acidosis, hyperketemia and other complications, the T2...Type 2 diabetes mellitus (T2MD) is a common chronic endocrine disease, if blood sugar isn't well controlled, except for hyperglycemia, also prone to metabolic acidosis, hyperketemia and other complications, the T2MD's condition gradually aggravated. Information shows, about 70% of T2MD patients have poor blood glucose control, and the main reason is the appropriate of insulin application. Research has shown, appropriate insulin can effectively control T2MD blood sugar, reduce adverse reaction. From July 2014 to June 2017, the hospital applied insulin pump to 108 patients in T2DM, the effect is satisfactory and the report is as follows.展开更多
目的:观察胰岛素泵强化治疗在2型糖尿病(T2DM)患者中的应用效果。方法:选取2024年6—12月上饶市立医院收治的80例T2DM患者,随机分为两组,各40例。对照组接受常规胰岛素治疗,试验组接受胰岛素泵强化治疗。比较两组治疗前和出院2个月后的...目的:观察胰岛素泵强化治疗在2型糖尿病(T2DM)患者中的应用效果。方法:选取2024年6—12月上饶市立医院收治的80例T2DM患者,随机分为两组,各40例。对照组接受常规胰岛素治疗,试验组接受胰岛素泵强化治疗。比较两组治疗前和出院2个月后的血糖指标、血脂指标、肝肾功能指标及住院时间、不良反应发生情况。结果:出院2个月后,试验组空腹血糖(FPG)、糖化血红蛋白(HbA1c)和餐后2 h血糖(2 h PG)低于对照组(P<0.05);出院2个月后,两组TC、LDL-C、TG、HDL-C、ALT、AST、血肌酐(Scr)、尿酸(UA)、尿素氮(BUN)、尿微量白蛋白(UMA)比较,差异无统计学意义(P>0.05)。试验组住院时间较对照组短,不良反应总发生率低于对照组(P<0.05)。结论:胰岛素泵强化治疗T2DM患者具有较好的临床效果,能够有效提高糖代谢功能、稳定血脂谱,治疗时间更短,不良反应发生风险更低,对肝肾功能无明显影响,具有较好的安全性。展开更多
In order to study the pathogenesis of hypertension associated with noninsulin dependent diabetes mellitus (NIDDM), Plasma glucose, insulin levels at fasting and following an oral glucose load were measured. Na +K +pum...In order to study the pathogenesis of hypertension associated with noninsulin dependent diabetes mellitus (NIDDM), Plasma glucose, insulin levels at fasting and following an oral glucose load were measured. Na +K +pump and Ca 2+ pump activities of red blood cell membrane were also assessed. Hypertensive patients with normal or impaired glucose tolerance (NGT, or IGT) had hyperinsulinemia. Obese hypertensive patients also had hyperinsulinemia, while nonobese hypertensive patients had no hyperinsulinemia, but exhibited a delay in insulin response to oral glucose tolerance test (OGTT). In multivariate analysis, considering the factors of age, BMI and plasma glucose level, DBP were still positively related to both 30 min insulin level and IAUC, but negatively correlated to activities of Na +K +pump and Ca 2+ pump. These results demonstrated that a link between obesity, hpertension and NIDDM is the insulin resistance and/or hyperinsulinemia.展开更多
文摘BACKGROUND Insulin pump therapy is a real breakthrough in managing diabetes Mellitus,particularly in children. It can deliver a tiny amount of insulin and decreases the need for frequent needle injections. It also helps to maintain adequate and optimal glycemic control to reduce the risk of metabolic derangements in different tissues.Children are suitable candidates for pump therapy as they need a more freestyle and proper metabolic control to ensure adequate growth and development.Therefore, children and their caregivers should have proper education and training and understand the proper use of insulin pumps to achieve successful pump therapy. The pump therapy continuously improves to enhance its performance and increase its simulation of the human pancreas. Nonetheless, there is yet a long way to reach the desired goal.AIM To review discusses the history of pump development, its indications, types, proper use, special conditions that may enface the children and their families while using the pump, its general care,and its advantages and disadvantages.METHODS We conducted comprehensive literature searches of electronic databases until June 30, 2022,related to pump therapy in children and published in the English language.RESULTS We included 118 articles concerned with insulin pumps, 61 were reviews, systemic reviews, and meta-analyses, 47 were primary research studies with strong design, and ten were guidelines.CONCLUSION The insulin pump provides fewer needles and can provide very tiny insulin doses, a convenient and more flexible way to modify the needed insulin physiologically, like the human pancreas, and can offer adequate and optimal glycemic control to reduce the risk of metabolic derangements in different tissues.
文摘To analyze the application effect of insulin pump in the treatment of diabetes. Methods: 100 cases of diabetic patients in our hospital were selected and randomly divided into the control group and the observation group. The control group received routine insulin therapy and the observation group received insulin pump therapy. The therapeutic effects of the two groups of patients were counted. Results: the therapeutic effect of the observation group was better than that of the control group (P<0.05). Conclusion: in the whole course of treatment for diabetic patients, a relatively safe way should be used to help patients control blood sugar. Insulin pump is one of the emerging clinical treatment methods. In the process of reasonable clinical control of blood sugar, the patient's blood sugar situation can be analyzed so as to help patients control blood sugar, which is welcomed by patients in clinic. The dosage of insulin pump used by patients should also be systematically explored, so as to provide patients with high-quality treatment services, improve patients' blood sugar, and avoid abnormal conditions of patients. It is recommended to promote it in a wide range of clinical practice.
文摘Type 2 diabetes mellitus (T2MD) is a common chronic endocrine disease, if blood sugar isn't well controlled, except for hyperglycemia, also prone to metabolic acidosis, hyperketemia and other complications, the T2MD's condition gradually aggravated. Information shows, about 70% of T2MD patients have poor blood glucose control, and the main reason is the appropriate of insulin application. Research has shown, appropriate insulin can effectively control T2MD blood sugar, reduce adverse reaction. From July 2014 to June 2017, the hospital applied insulin pump to 108 patients in T2DM, the effect is satisfactory and the report is as follows.
文摘目的:观察胰岛素泵强化治疗在2型糖尿病(T2DM)患者中的应用效果。方法:选取2024年6—12月上饶市立医院收治的80例T2DM患者,随机分为两组,各40例。对照组接受常规胰岛素治疗,试验组接受胰岛素泵强化治疗。比较两组治疗前和出院2个月后的血糖指标、血脂指标、肝肾功能指标及住院时间、不良反应发生情况。结果:出院2个月后,试验组空腹血糖(FPG)、糖化血红蛋白(HbA1c)和餐后2 h血糖(2 h PG)低于对照组(P<0.05);出院2个月后,两组TC、LDL-C、TG、HDL-C、ALT、AST、血肌酐(Scr)、尿酸(UA)、尿素氮(BUN)、尿微量白蛋白(UMA)比较,差异无统计学意义(P>0.05)。试验组住院时间较对照组短,不良反应总发生率低于对照组(P<0.05)。结论:胰岛素泵强化治疗T2DM患者具有较好的临床效果,能够有效提高糖代谢功能、稳定血脂谱,治疗时间更短,不良反应发生风险更低,对肝肾功能无明显影响,具有较好的安全性。
文摘In order to study the pathogenesis of hypertension associated with noninsulin dependent diabetes mellitus (NIDDM), Plasma glucose, insulin levels at fasting and following an oral glucose load were measured. Na +K +pump and Ca 2+ pump activities of red blood cell membrane were also assessed. Hypertensive patients with normal or impaired glucose tolerance (NGT, or IGT) had hyperinsulinemia. Obese hypertensive patients also had hyperinsulinemia, while nonobese hypertensive patients had no hyperinsulinemia, but exhibited a delay in insulin response to oral glucose tolerance test (OGTT). In multivariate analysis, considering the factors of age, BMI and plasma glucose level, DBP were still positively related to both 30 min insulin level and IAUC, but negatively correlated to activities of Na +K +pump and Ca 2+ pump. These results demonstrated that a link between obesity, hpertension and NIDDM is the insulin resistance and/or hyperinsulinemia.
