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Assessment of Optimal Use, Maintenance, Repair and Calibration of Radiation Monitoring Instruments in Nigeria
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作者 Samuel Mofolorunsho Oyeyemi Olumide Olaife Akerele +5 位作者 Sunday Ufuoma Obarhua Francis Adole Agada Wasiu Kofoworola Ayuba Helen Enikpi Alakiu David Olakanmi Olaniyi Ethel Ebere Ofoegbu 《World Journal of Nuclear Science and Technology》 2025年第1期1-16,共16页
The response and performance of radiation detectors for accurate measurements and effective use for radiological safety in medical, industrial, and nuclear sectors are based on the optimal use, maintenance, repair and... The response and performance of radiation detectors for accurate measurements and effective use for radiological safety in medical, industrial, and nuclear sectors are based on the optimal use, maintenance, repair and calibration of radiation monitoring instruments in a secondary standard dosimetry laboratory. In Nigeria, the suboptimal performances of these instruments are attributed to inadequate maintenance practices, insufficient calibration, and limited awareness of proper equipment handling for optimal use. This study assesses the current practices related to the optimal use, maintenance, repair, and calibration of radiation detection equipment across Nigeria’s six geopolitical zones. Using a cross-sectional survey approach, data were collected from Ninety (90) radiation monitoring equipment operators, Radiation Safety Officers, and frontline responders to evaluate their knowledge, awareness, and practices concerning equipment usage, operation, storage, handling, and calibration. The findings reveal significant gaps in knowledge of usage (trained is 43.2%, not trained is 56.8%) and inconsistencies in maintenance practices (as indicated by the regression analysis (β = 0.51, p < 0.01), particularly regarding specialized instruments such as the PackEye, Mobile Detection System (MDS), Radionuclide Identifinder (RID), and Personal Radiation Detectors (PRD). While there is high awareness of the need for regular calibration and handling training, the lack of standardized protocols and training alignment poses challenges to the effective use of these instruments. This study underscores the importance of comprehensive training programs, standardized maintenance protocols, and enhanced awareness initiatives to optimize the usage, performance and safety of radiation monitoring instruments in Nigeria. 展开更多
关键词 Radiation Monitoring instruments Detectors CALIBRATION Radiation Safety Officers PackEye Radionuclide Identifinder Personal Radiation Detectors
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The Impact of Quality Nursing on Instrument Quality Management and Department Satisfaction in the Management of Reusable Instruments in the Central Sterile Supply Department
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作者 Jie Li 《Journal of Clinical and Nursing Research》 2025年第6期385-391,共7页
Objective:To evaluate the effectiveness of quality nursing in the management of reusable instruments in the Central Sterile Supply Department(CSSD).Methods:Eleven nurses from the CSSD department were selected from Jan... Objective:To evaluate the effectiveness of quality nursing in the management of reusable instruments in the Central Sterile Supply Department(CSSD).Methods:Eleven nurses from the CSSD department were selected from January to October 2024,and quality nursing activities were implemented in the management of reusable instruments.The completion of quality indicators was analyzed.The instrument quality management scores,department satisfaction,and nurses’professional ability scores before and after nursing management were compared.Results:After nursing intervention,the qualified rates of initial cleaning and final cleaning of sterilization instruments were 99.66%and 100%,respectively.The qualified rate of packaging was 99.97%,the wet package rate was 0.1‰,the loading qualified rate was 99.88%,and the qualified rate of distribution was 99.99%.After nursing intervention,the nurses’instrument quality management scores,department satisfaction,and nurses’professional ability scores were all higher than those before nursing intervention(P<0.05).Conclusion:Quality nursing activities can improve the cleaning,packaging,and sterilization qualified rates of reusable instruments in the CSSD,enhance the effect of instrument quality management,obtain higher department satisfaction from nurses,cultivate their professional abilities,and possess significant nursing management advantages. 展开更多
关键词 Quality nursing Central Sterile Supply Department Reusable instrument management instrument quality management Department satisfaction
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Factors that influence long term instrumentation stability in patients with unstable thoracolumbar injuries
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作者 Andrey E Bokov Svetlana Y Kalinina +3 位作者 Daria A Kulagina Kseniia S Lopyrina Vladimir V Klinshov Anatolii A Bulkin 《World Journal of Orthopedics》 2025年第8期93-102,共10页
BACKGROUND Pedicle screw fixation is frequently used to treat unstable thoracolumbar injuries;however,the rate of instrumentation failure remains considerable.The primary contributing factor leading to instrumentation... BACKGROUND Pedicle screw fixation is frequently used to treat unstable thoracolumbar injuries;however,the rate of instrumentation failure remains considerable.The primary contributing factor leading to instrumentation failure is poor bone quality.On the other hand,some evidence suggests that surgical tactics can influence long-term instrumentation stability.AIM To assess factors that influence the stability of spinal instrumentation in patients with thoracolumbar injuries.METHODS This study is a non-randomized single center ambispective evaluation of 204 consecutive patients(117 men;87 women)with unstable thoracolumbar injuries.All patients underwent either stand-alone or combined with anterior column reconstruction instrumentation.In cases with spinal cord and nerve root injuries,either posterior or anterior decompression were performed.Patients with pedicle screw loosening were identified via computed tomography imaging.Out of those,cases with clinically significant instrumentation failure were registered.RESULTS The rate of pedicle screw loosening detected by computed tomography was inversely correlated with bone radiodensity figures and an increased association with the number of instrumented levels,residual kyphotic deformity,laminectomy,and lumbosacral fixation.Intermediate screws and anterior reconstruction were associated with a clinically relevant decreased risk of pedicle screw loosening development.Either complete or partial posterior fusion within instrumented levels was capable of decreasing instrumentation failure risk,while extensive decompression with laminectomy and at least one-level total facetectomy were associated with an increased risk of instrumentation failure.Anterior decompression does not have a negative impact on instrumentation stability.CONCLUSION Intermediate screws,anterior reconstruction and posterior tension band preservation are associated with decreased rates of instrumentation instability development.Posterior fusion is beneficial in terms of instrumentation failure prevention. 展开更多
关键词 instrumentation stability Unstable thoracolumbar injuries Pedicle screw loosening Anterior reconstruction Posterior decompression
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"Silk Road People-to-People Connectivity"China-Cambodia Traditional Instrument Concert Held in Phnom Penh
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《International Understanding》 2025年第2期46-47,共2页
On April 6th,the"Silk Road People-to-People Connectivity"China-Cambodia Traditional Instrument Concert was successfully held in Phnom Penh.The event was attended by Li Ji,Cultural Counsellor of the Chinese E... On April 6th,the"Silk Road People-to-People Connectivity"China-Cambodia Traditional Instrument Concert was successfully held in Phnom Penh.The event was attended by Li Ji,Cultural Counsellor of the Chinese Embassy in Cambodia,officials from Ministry of Culture and Fine Arts of Cambodia and Ministry of Commerce of Cambodia,along with vips from various sectors. 展开更多
关键词 fine arts cultural exchange people people connectivity China Cambodia Silk Road traditional instrument concert Phnom Penh
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An Instrumented Sharp Indentation Method for Measuring Equibiaxial Residual Stress without Using Stress-Free Specimens
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作者 Guangjian Peng Saifei Li +3 位作者 Liang Zhang Peijian Chen Wei Xiong Taihua Zhang 《Acta Mechanica Solida Sinica》 2025年第2期290-299,共10页
The presence of residual stresses in materials or engineering structures can significantly influence their mechanical per-formance.Accurate measurement of residual stresses is of great importance to ensure their in-se... The presence of residual stresses in materials or engineering structures can significantly influence their mechanical per-formance.Accurate measurement of residual stresses is of great importance to ensure their in-service reliability.Although numerous instrumented indentation methods have been proposed to evaluate residual stresses,the majority of them require a stress-free reference sample as a comparison benchmark,thereby limiting their applicability in scenarios where obtaining stress-free reference samples is challenging.In this work,through a number of finite element simulations,it was found that the loading exponent of the loading load-depth curve and the recovered depth during unloading are insensitive to residual stresses.The loading curve of the stress-free specimen was virtually reconstructed using such stress-insensitive parameters extracted from the load-depth curves of the stressed state,thus eliminating the requirement for stress-free reference samples.The residual stress was then correlated with the fractional change in loading work between stressed and stress-free loading curves through dimensional analysis and finite element simulations.Based on this correlation,an instrumented sharp indentation method for measuring equibiaxial residual stress without requiring a stress-free specimen was established.Both numerical and experimental verifications were carried out to demonstrate the accuracy and reliability of the newly proposed method.The maximum relative error and absolute error in measured residual stresses are typically within±20%and±20 MPa,respectively. 展开更多
关键词 Experimental mechanics Residual stress measurement instrumented indentation Finite element simulation Dimensional analysis
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Research on the Efficacy Claims and Evaluation Methods of a Beauty Instrument
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作者 Mao Yiyu 《China Detergent & Cosmetics》 2025年第1期58-63,共6页
The efficacy requirements of cosmetic instruments and explored their efficacy evaluation methods was investigated.The efficacy and claims of common cosmetic instruments on the market were investigated,and human clinic... The efficacy requirements of cosmetic instruments and explored their efficacy evaluation methods was investigated.The efficacy and claims of common cosmetic instruments on the market were investigated,and human clinical trials were conducted to evaluate the efficacy of household cosmetic instruments.Household cosmetic instruments mainly include technologies such as sound wave,ion conduction,LED light,EMS microcurrent,RF radio frequency,and laser.This paper took microcurrent as an example to explore its efficacy claim methods.In human test I,the water content in the stratum corneum of the forearms of 31 subjects increased significantly compared with the blank control after 8 h.In human test II,30 subjects showed significant decreases in skin texture R5,transepidermal water loss TEWL,skin firmness F4 value,skin elasticity R2 value,overall size and depth of facial wrinkles,and facial jawline angle,and a significant increase in facial gloss value.The results showed that the cosmetic instrument had effects of moisturizing,improving facial evenness,repairing barrier,improving skin elasticity and firmness,and improving facial edema. 展开更多
关键词 household cosmetic instrument microcurrent efficacy testing human clinical trial
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Expert consensus on management of instrument separation in root canal therapy
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作者 Yi Fan Yuan Gao +33 位作者 Xiangzhu Wang Bing Fan Zhi Chen Qing Yu Ming Xue Xiaoyan Wang Zhengwei Huang Deqin Yang Zhengmei Lin Yihuai Pan Jin Zhao Jinhua Yu Zhuo Chen Sijing Xie He Yuan Kehua Que Shuang Pan Xiaojing Huang Jun Luo Xiuping Meng Jin Zhang Yi Du Lei Zhang Hong Li Wenxia Chen Jiayuan Wu Xin Xu Jing Zou Jiyao Li Dingming Huang Lei Cheng Tiemei Wang Benxiang Hou Xuedong Zhou 《International Journal of Oral Science》 2025年第3期301-313,共13页
Instrument separation is a critical complication during root canal therapy,impacting treatment success and long-term tooth preservation.The etiology of instrument separation is multifactorial,involving the intricate a... Instrument separation is a critical complication during root canal therapy,impacting treatment success and long-term tooth preservation.The etiology of instrument separation is multifactorial,involving the intricate anatomy of the root canal system,instrument-related factors,and instrumentation techniques.Instrument separation can hinder thorough cleaning,shaping,and obturation of the root canal,posing challenges to successful treatment outcomes.Although retrieval of separated instrument is often feasible,it carries risks including perforation,excessive removal of tooth structure and root fractures.Effective management of separated instruments requires a comprehensive understanding of the contributing factors,meticulous preoperative assessment,and precise evaluation of the retrieval difficulty.The application of appropriate retrieval techniques is essential to minimize complications and optimize clinical outcomes.The current manuscript provides a framework for understanding the causes,risk factors,and clinical management principles of instrument separation.By integrating effective strategies,endodontists can enhance decision-making,improve endodontic treatment success and ensure the preservation of natural dentition. 展开更多
关键词 root canal therapy instrument separation retrieval techniques tooth preservation root canal therapyimpacting endodontic treatment success root canal root canalposing
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Virtual force node deployment algorithm of field observation instrument based on voronoi diagram
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作者 HUO Jiuyuan WANG Lei 《Journal of Measurement Science and Instrumentation》 2025年第3期435-445,共11页
Aiming at node deployment in the monitoring area of the field observation instrument network in the cold and arid regions,we propose a virtual force algorithm based on Voronoi diagram(VFAVD),which adopts probabilistic... Aiming at node deployment in the monitoring area of the field observation instrument network in the cold and arid regions,we propose a virtual force algorithm based on Voronoi diagram(VFAVD),which adopts probabilistic sensing model that is more in line with the actual situation.First,the Voronoi diagram is constructed in the monitoring area to determine the Thiessen polygon of each node.Then,the virtual force on each node is calculated,and the node update its position according to the direction and size of the total force,so as to achieve the purpose of improving the network coverage rate.The simulation results show that the proposed algorithm can effectively improve the coverage rate of the network,and also has a good effect on the coverage uniformity. 展开更多
关键词 field observation instrument network node deployment Voronoi diagram virtual force network coverage rate
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A Study on Integrative and Instrumental Motivations and Learning Strategies of PhD Dissertation
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作者 Zhou Li Huisuan Wei 《Journal of Contemporary Educational Research》 2025年第1期163-168,共6页
The research topic of the author’s PhD dissertation is“The Impact of Motivation Cultivation on English Autonomous Learning among University Students in Hunan,China—A Mediating Role of Learning Strategy.”Within thi... The research topic of the author’s PhD dissertation is“The Impact of Motivation Cultivation on English Autonomous Learning among University Students in Hunan,China—A Mediating Role of Learning Strategy.”Within this topic,three key variables are identified:the dependent variable(DV),the independent variable(IV),and the mediating variable(MV).Specifically,the DV refers to English autonomous learning,the IV refers to motivation,and the MV refers to learning strategy.The research establishes that the MV(learning strategy)is an integral component of information processing theory(IPT).Consequently,the dissertation incorporates integrative and instrumental motivation theories alongside IPT as its foundational theoretical framework.This paper aims to explore the theoretical framework of the PhD dissertation in detail,focusing on the interplay of these three theories. 展开更多
关键词 English autonomous learning Motivation Learning strategy Integrative motivation theory instrumental motivation theory Information processing theory
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Tentative exploring the construction of experimental technician team of large-scale instrument platforms in universities-Taking Peking University School of Pharmaceutical Sciences as an example
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作者 Yuan Wang Xun Wang 《Journal of Chinese Pharmaceutical Sciences》 2025年第4期392-399,共8页
This study examined the development of technician teams on large-scale instrument platforms in universities,using the State Key Laboratory of Natural and Biomimetic Drugs in the Peking University School of Pharmaceuti... This study examined the development of technician teams on large-scale instrument platforms in universities,using the State Key Laboratory of Natural and Biomimetic Drugs in the Peking University School of Pharmaceutical Sciences as a case study.Data were collected through questionnaire surveys and interviews conducted in 2017,followed by a questionnaire survey in 2023,offering both subjective and objective insights.The evolution of the platform’s technician team over the past 5 years was analyzed,highlighting key experiences and identifying ongoing challenges.Recommendations to enhance technician team development include recruiting skilled faculty,clearly defining job responsibilities,and refining the assessment and incentive systems. 展开更多
关键词 Large-scale instrument platform Experimental technician team Scientific research management
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Application and Innovation of Automotive Electronics Structural Design in Center Console Instruments
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作者 Peijie Jia 《Journal of Electronic Research and Application》 2025年第4期320-326,共7页
This paper introduces the key design aspects of automotive center console instrument systems,including hardware architecture,ergonomics,antenna layout,etc.It elaborates on the application and advantages of various adv... This paper introduces the key design aspects of automotive center console instrument systems,including hardware architecture,ergonomics,antenna layout,etc.It elaborates on the application and advantages of various advanced technologies,such as 3D printing and dual-color injection molding.Additionally,it discusses advancements in structural design,as well as future challenges and the trend of multidisciplinary collaborative innovation. 展开更多
关键词 Automotive center console instrument Structural design Technology application
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Glaucoma surgery experiments using digital microscope-integrated optical coherence tomography and OCT-compatible instruments 被引量:2
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作者 Tianliang Jiang Jinyu Fan +2 位作者 Ning Tang Yi He Guohua Shi 《Journal of Innovative Optical Health Sciences》 SCIE EI CSCD 2024年第5期105-113,共9页
There is a certain failure rate in traditional glaucoma surgery because of the lack of depth information in microscope images.In this work,we present a digital microscope-integrated optical coherence tomography(MIOCT)... There is a certain failure rate in traditional glaucoma surgery because of the lack of depth information in microscope images.In this work,we present a digital microscope-integrated optical coherence tomography(MIOCT)system and several custom-made OCT-compatible instruments for glaucoma surgery.Sixteen ophthalmologists were asked to perform trabeculectomy and canaloplasty on live porcine eyes using the system and instruments.After surgery,a subjective feedback survey about the user experience was taken.The experiment results showed that our system can help surgeons easily locate important tissue structures during surgery.The custom-made instruments also solved the shadowing problem in OCT imaging.Surgeons preferred to use the system in their future practice. 展开更多
关键词 Microscope-integrated optical coherence tomography OCT-compatible instruments glaucoma surgery TRABECULECTOMY CANALOPLASTY
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The CCD instrument background of the SMILE SXI 被引量:2
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作者 M.W.J.Hubbard O.Hetherington +6 位作者 D.J.Hall T.W.Buggey S.Parsons T.Arnold A.Holland C.Pagani S.Sembay 《Earth and Planetary Physics》 EI CSCD 2024年第1期15-24,共10页
The ESA and CAS SMILE mission orbit is highly elliptical and will pass through multiple radiation environments.The Soft X-ray Imager(SXI)instrument aboard has a radiation shutter door designed to close when the surrou... The ESA and CAS SMILE mission orbit is highly elliptical and will pass through multiple radiation environments.The Soft X-ray Imager(SXI)instrument aboard has a radiation shutter door designed to close when the surrounding radiation flux is high.The shutter door will close when passing below an altitude threshold to protect against trapped particles in the Earth’s Van Allen Belts.Therefore,two radiation environments can be approximated based on the shutter door position:open and closed.The instrument background for the CCDs(Charge-Coupled Devices)that form the focal plane array of the SXI were evaluated for the two environments.Due to the correlation of the space environment with the solar cycle,the solar minima and maxima,the background was also evaluated at these two extremes.The results demonstrated that the highest instrument background will occur during solar minima due to the main contributing source being Galactic Cosmic Rays(GCRs).It was also found that the open background was highest for solar minima and that the closed background was highest during solar maxima.This is due to the radiation shutter door acting as a scattering centre and the changes in the energy flux distribution of the GCRs between the two solar extremes. 展开更多
关键词 instrument background X-ray astronomy space radiation
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Reform of Teaching Practice of Modern Instrumental Analysis in Biotechnology Programs 被引量:1
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作者 Kun TANG Tong LIN +3 位作者 Zhenxia SHI Jie QIAO Chunyan XIE Lixin DU 《Agricultural Biotechnology》 2024年第3期93-95,共3页
Through the online and offline practical reform of the Modern Instrumental Analysis course of biotechnology majors from teaching content,teaching method,teaching demonstration to teaching effect,the traditional single... Through the online and offline practical reform of the Modern Instrumental Analysis course of biotechnology majors from teaching content,teaching method,teaching demonstration to teaching effect,the traditional single offline lecture is transformed into diversified and interactive modern teaching.The practical reform enriches and optimizes the course content,perfects and improves the course assessment system,and improves the teaching quality.It achieves the student-centered and application-oriented teaching goal,and also provides reference for further cultivating high-quality applied talents. 展开更多
关键词 Modern instrumental analysis BIOTECHNOLOGY Online and offline Reform of teaching
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Improving atmospheric CO_(2)retrieval based on the collaborative use of Greenhouse gases Monitoring Instrument and Directional Polarimetric Camera sensors on Chinese hyperspectral satellite GF5-02 被引量:1
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作者 Hanhan Ye Hailiang Shi +7 位作者 Xianhua Wang Erchang Sun Chao Li Yuan An Shichao Wu Wei Xiong Zhengqiang Li Jochen Landgraf 《Geo-Spatial Information Science》 CSCD 2024年第3期572-584,共13页
The Greenhouse Gas Monitoring Instrument(GMI)onboard the Chinese hyperspectral satellite GF5-02 can provide abundant observations of global atmospheric CO_(2),which plays an important role in climate research.CO_(2)re... The Greenhouse Gas Monitoring Instrument(GMI)onboard the Chinese hyperspectral satellite GF5-02 can provide abundant observations of global atmospheric CO_(2),which plays an important role in climate research.CO_(2)retrieval precision is the key to determining the application value of the GMI.To reduce the influence of atmospheric scattering on retrieval,we combined the Directional Polarimetric Camera(DPC)data on the same satellite to improve the anti-interference ability of GMI CO_(2)retrieval and ensure its retrieval precision.To realize the reliability and feasibility of the collaborative use of the GMI and DPC,this paper designs the pointing registration method of the GMI based on coastline observations,the spatial resolution matching method and the collaborative cloud screening method of the GMI and DPC observations.Combined with the DPC,which supplied the spectral data and aerosol product,the retrieval ability of the coupled bidirectional reflectance distribution function CO_(2)retrieval(CBCR)method developed for GMI CO_(2)retrieval was improved,with the retrieval efficiency of CO_(2)products increasing by 27%,and the CO_(2)retrieval precision increasing from 3.3 ppm to 2.7 ppm.Moreover,collaborative use not only guaranteed the GMI’s ability to detect global and area CO_(2)concentration distribution characteristics,such as significant concentration differences between the Northern and Southern Hemispheres in winter and high CO_(2)concentrations in urban agglomeration areas caused by human activities,but also extended the GMI’s potential for monitoring anomalous events,such as the Tonga volcanic eruption. 展开更多
关键词 CO_(2)retrieval Greenhouse Gas Monitoring instrument(GMI) Directional Polarimetric Camera(DPC) collaborative use
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大型科研仪器发展现状与共享实践 被引量:5
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作者 周琼琼 陈志辉 +3 位作者 王晋 徐振国 岳琦 杨丽 《实验室研究与探索》 北大核心 2025年第4期241-246,262,共7页
大型科研仪器是科学研究的核心支撑工具,也是推动科技成果转化、提升国家竞争力的重要基础。经过多年建设与发展,我国大型科研仪器已经具备一定规模,其开放共享管理体系不断完善,为科技创新发展提供了重要支撑。通过研究大型科研仪器的... 大型科研仪器是科学研究的核心支撑工具,也是推动科技成果转化、提升国家竞争力的重要基础。经过多年建设与发展,我国大型科研仪器已经具备一定规模,其开放共享管理体系不断完善,为科技创新发展提供了重要支撑。通过研究大型科研仪器的规模、布局、国产化以及开放共享等情况,分析了大型科研仪器发展的现状与特点,总结了大型科研仪器开放共享的实践与经验,从优化网络平台、强化共享考核、丰富应用场景、创新共享机制等方面,提出促进科研仪器使用效率与共享水平的思考,以期为科技资源优化配置与创新驱动发展政策制定提供决策参考。 展开更多
关键词 大型科研仪器 仪器发展 仪器共享 开放共享
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高校大型仪器设备开放共享协同治理模式探索 被引量:7
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作者 樊冰 郭春伟 +2 位作者 姜斌 郦文菁 薛凌云 《实验室研究与探索》 北大核心 2025年第1期235-240,256,共7页
高校大型仪器设备是开展高水平科学研究和培养高层次人才的重要工具,是创新驱动发展的“助推器”,对提升国家创新整体效能,促进新质生产力发展具有重要意义。梳理国内外高校大型仪器设备现状,分析导致开放共享效益不高的4个主要原因:购... 高校大型仪器设备是开展高水平科学研究和培养高层次人才的重要工具,是创新驱动发展的“助推器”,对提升国家创新整体效能,促进新质生产力发展具有重要意义。梳理国内外高校大型仪器设备现状,分析导致开放共享效益不高的4个主要原因:购置论证不充分、共享机制不健全、共享氛围不浓郁和维修维护基金不到位。在此基础上,从全生命周期管理视角,制定大型仪器设备开放共享策略。运用系统科学观,从供应侧、需求侧、连接侧、政府和合作方多维度,构建大型仪器设备开放共享“摸、理、升、推、合”协同治理模式。通过创新实践,显著提升了大型仪器设备使用绩效,为高校大型仪器设备开放共享提供了实践参考,对促进科技创新和资源优化配置具有重要价值。 展开更多
关键词 大型仪器设备 开放共享 协同治理 供给侧改革
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Special topic on new instruments and sensing technologies
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作者 Qi Xiao Yong Yang 《Journal of Measurement Science and Instrumentation》 CAS CSCD 2024年第4期I0001-I0001,共1页
New instruments and sensing technologies have extensive applications in non-destructive testing,safety monitoring,human-computer interaction,precision sensing,and other fields.The emergence of new structural materials... New instruments and sensing technologies have extensive applications in non-destructive testing,safety monitoring,human-computer interaction,precision sensing,and other fields.The emergence of new structural materials,new preparation processes,and new sensing theories has driven the development of precision measurement instruments and intelligent sensing technology with the rapid development of electromagnetics,optics,and materials science. 展开更多
关键词 COMPUTER instrumentS OPTICS
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Exploring the Mysteries of the Universe, and Innovation Leading the Future——Astronomical Techniques and Instruments
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《Astronomical Techniques and Instruments》 CSCD 2024年第1期I0001-I0001,共1页
Dear Readers:Astronomical Techniques and Instruments is a professional English journal of open access devoted to recent develop-ments,discoveries,and theories in astronomical techniques,methods,and instruments.It will... Dear Readers:Astronomical Techniques and Instruments is a professional English journal of open access devoted to recent develop-ments,discoveries,and theories in astronomical techniques,methods,and instruments.It will serve as a platform for dis-course,learning,and information sharing for astronomic and astrophysics professionals worldwide. 展开更多
关键词 JOURNAL devoted instrumentS
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端粒长度与10种常见肌肉骨骼疾病的关系孟德尔随机化分析 被引量:4
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作者 罗伟东 蒲彬 +3 位作者 古鹏 黄枫 郑晓辉 陈福洪 《中国组织工程研究》 CAS 北大核心 2025年第3期654-660,共7页
背景:多项观察性研究表明,端粒长度与肌肉骨骼疾病之间存在潜在的关联,然而它们之间的潜在机制仍不清楚。目的:利用两样本孟德尔随机化分析来探索端粒长度与肌肉骨骼疾病之间的遗传因果关系。方法:从英国生物银行中获得端粒长度的全基... 背景:多项观察性研究表明,端粒长度与肌肉骨骼疾病之间存在潜在的关联,然而它们之间的潜在机制仍不清楚。目的:利用两样本孟德尔随机化分析来探索端粒长度与肌肉骨骼疾病之间的遗传因果关系。方法:从英国生物银行中获得端粒长度的全基因组关联研究汇总数据。从FinnGen财团中获得了关于10种常见肌肉骨骼疾病(骨坏死、骨髓炎、骨质疏松、类风湿关节炎、腰痛、椎管狭窄、痛风、肩周炎、强直性脊柱炎和下肢深静脉血栓)的全基因组关联研究汇总数据。使用逆方差加权、孟德尔随机化-Egger和加权中位数方法评估端粒长度与10种肌肉骨骼疾病的因果关系,逆方差加权作为主要的孟德尔随机化分析方法,并进行敏感性分析探讨结果稳健性。结果与结论:①逆方差加权法结果表明,遗传预测的端粒长度与类风湿关节炎(OR=0.78,95%CI:0.64-0.95,P=0.015)和骨坏死(OR=0.56,95%CI:0.36-0.90,P=0.016)风险之间存在负向因果关系,但未发现端粒长度与其他8种肌肉骨骼疾病之间存在因果关系(P均>0.05)。②敏感性分析结果表明因果关系稳健,孟德尔随机化-Egger截距分析未检测到潜在的水平多效性(P均>0.05)。③此项孟德尔随机化研究支持端粒长度对类风湿关节炎和骨坏死的保护作用的结论,然而,未来将需要更多的基础和临床研究来验证。 展开更多
关键词 端粒长度 肌肉骨骼疾病 孟德尔随机化 全基因组关联研究 单核苷酸多态性 因果关系 工具变量
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