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Innovative Strategies to Overcome Stability Challenges of Single‑Atom Nanozymes
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作者 Rong Guo Qiuzheng Du +3 位作者 Yaping He Haoan Wu Yu Zhang Ziwei Jing 《Nano-Micro Letters》 2026年第3期725-756,共32页
Single-atom nanozymes(SAzymes)exhibit exceptional catalytic efficiency due to their maximized atom utilization and precisely modulated metalcarrier interactions,which have attracted significant attention in the biomed... Single-atom nanozymes(SAzymes)exhibit exceptional catalytic efficiency due to their maximized atom utilization and precisely modulated metalcarrier interactions,which have attracted significant attention in the biomedical field.However,stability issues may impede the clinical translation of SAzymes.This review provides a comprehensive overview of the applications of SAzymes in various biomedical fields,including disease diagnosis(e.g.,biosensors and diagnostic imaging),antitumor therapy(e.g.,photothermal therapy,photodynamic therapy,sonodynamic therapy,and immunotherapy),antimicrobial therapy,and anti-oxidative stress therapy.More importantly,the existing challenges of SAzymes are discussed,such as metal atom clustering and active site loss,ligand bond breakage at high temperature,insufficient environment tolerance,biosecurity risks,and limited catalytic long-term stability.Finally,several innovative strategies to address these stability concerns are proposed—synthesis process optimization(space-limited strategy,coordination site design,bimetallic synergistic strategy,defect engineering strategy,atom stripping-capture),surface modification,and dynamic responsive design—that collectively pave the way for robust,clinically viable SAzymes. 展开更多
关键词 Single-atom nanozymes Clinical translation Stability issues innovative strategies BIOCOMPATIBILITY
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From seed to whole plant:An innovative visual marker system to enhance selection efficiency in soybean genome editing
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作者 Tingwei Yan Xueyan Qian +5 位作者 Hong Pan Jiarui Han Qi Wang Chang Liu Dongquan Guo Xiangguo Liu 《Journal of Integrative Agriculture》 2026年第2期820-823,共4页
Emerging and powerful genome editing tools,particularly CRISPR/Cas9,are facilitating functional genomics research and accelerating crop improvement(Jiang et al.2021;Cao et al.2023;Chen C et al.2023;Liu et al.2023a).Ho... Emerging and powerful genome editing tools,particularly CRISPR/Cas9,are facilitating functional genomics research and accelerating crop improvement(Jiang et al.2021;Cao et al.2023;Chen C et al.2023;Liu et al.2023a).However,the detection and screening of transgenic lines remain major bottlenecks,being time-consuming,labor-intensive,and inefficient during transformation and subsequent mutation identification.A simple and efficient visual marker system plays a critical role in addressing these challenges.Recent studies demonstrated that the GmW1 and RUBY reporter systems were used to obtain visual transgenic soybean(Glycine max) plants(Chen L et al.2023;Chen et al.2024). 展开更多
关键词 accelerating crop improvement jiang mutation identificationa enhance selection efficiency SEED functional genomics research detection screening transgenic lines genome editing toolsparticularly innovative visual marker system
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Modernization of traditional Chinese medicine in cancer therapy:“3 D”innovative Chinese medicine
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作者 Hui Liu Yunxiao Ge Zigang Dong 《Chinese Journal of Natural Medicines》 2026年第2期189-202,共14页
Traditional Chinese medicine(TCM)has garnered increasing attention globally,with its modernization becoming a prominent research focus both within China and internationally.However,the lack of a precise definition for... Traditional Chinese medicine(TCM)has garnered increasing attention globally,with its modernization becoming a prominent research focus both within China and internationally.However,the lack of a precise definition for TCM modernization has hindered clear guidance for its development.Additionally,cancer remains a significant global public health challenge,largely untreatable with current methods.Therefore,a comprehensive understanding of TCM modernization is crucial for its evolution,revolution,drug discovery,and cancer therapy.This study provides an overview of the history,theory,characteristics,and evolution of TCM,highlighting its potential in cancer prevention and treatment.We propose a definition for TCM modernization,innovative Chinese medicine(ICM),and elucidate strategies to elevate TCM from a supporting role to a leading one.Electronic databases such as PubMed,Web of Science,ScienceDirect,and Clinical Trials were utilized to retrieve relevant literature spanning from 1979 to 2024,with most publications being from the last five years,using keywords like“Traditional Chinese medicine”,“Cancer”,“Mechanism”,and“Clinical trial”.In this study,we introduce the theory of TCM modernization following target identification and initial compound screening:ICM,defined by“3 D”elements:definite active ingredient composition and content,determined functional mechanism,and detection through evidence-based medicine.Overall,the“3 D”definition of ICM will establish a standard for ICM,accelerate TCM modernization,enhance drug discovery targeting cancer and various human diseases,and benefit patients worldwide. 展开更多
关键词 Traditional Chinese medicine innovative Chinese medicine Definite active ingredient composition and content Determined functional mechanism Detection through evidence-based medicine Cancer therapy Drug discovery
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The Xu-Argument:An Innovative Approach to Second Language Acquisition—An Interview With Prof.Wang Chuming
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作者 Min Wang 《Chinese Journal of Applied Linguistics》 2026年第1期8-20,159,共14页
This interview examines the theoretical foundations,pedagogical applications,developmental trajectory,and future directions of the xu-argument.Professor Wang Chuming offers a comprehensive account of the xu-argument,c... This interview examines the theoretical foundations,pedagogical applications,developmental trajectory,and future directions of the xu-argument.Professor Wang Chuming offers a comprehensive account of the xu-argument,clarifying its theoretical framework,the learning mechanisms underlying xu,and its interface with international theories of second language acquisition(SLA).From the perspective of the xu-argument,he proposes novel interpretations of core issues in SLA.Drawing on the development of the xu-argument,Wang further discusses the essence,directions,and methodology of innovation in SLA theory.He emphasizes that theoretical advances must capture and illuminate underlying natural laws,arguing that innovative approaches are typically rooted in deep reflection on common sense.He also calls for theoretical innovation in SLA in the Chinese context,advocating a robust research paradigm that shifts from local observation to global theoretical generalization,thereby promoting bottom-up theoretical development.In closing,he highlights the promising prospects for SLA theory in the era of artificial intelligence. 展开更多
关键词 Wang Chuming the xu-argument second language acquisition theoretical innovation
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Editorial for Innovative Young Scientist Special Issue
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作者 Aixiang Wu 《International Journal of Minerals,Metallurgy and Materials》 2025年第6期1285-1285,共1页
Welcome to the Special Issue highlighting the latest innovative research conducted by young scientists who have received the 2023 or the 2024 Innovative Young Scientist Awards.Established in 2023 by the University of ... Welcome to the Special Issue highlighting the latest innovative research conducted by young scientists who have received the 2023 or the 2024 Innovative Young Scientist Awards.Established in 2023 by the University of Science and Technology Beijing,the Innovative Young Scientist Award recognizes exceptional young scientists who have demonstrated sustained engagement in frontier research across mineral science,metallurgy,and materials science,with significant scientific contributions.Committed to fostering the next generation of scientific leaders,the award supports researchers aged under 45.Since its inception,the honor has been bestowed upon 20 recipients,with 10 outstanding researchers selected annually from a competitive pool of approximately 100 applicants. 展开更多
关键词 METALLURGY materials science innovative young scientist innovative Young Scientist Award mineral science University Science Technology Beijing scientific leadership frontier research
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Leaders’ expectations of innovation and employees’ innovative behavior: The roles of employees’ expected positive performance outcomes and innovative self-efficacy
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作者 Qian Ma Hao Zhou 《Journal of Psychology in Africa》 2025年第1期7-19,共13页
Employees’innovative performance determines an organization’s innovation,which critically impacts its structural optimization and sustainability.Applying expectancy theory,we examined how and when the Pygmalion effe... Employees’innovative performance determines an organization’s innovation,which critically impacts its structural optimization and sustainability.Applying expectancy theory,we examined how and when the Pygmalion effect occurs in the relationship between leaders’expectations of innovation and employee innovative behavior.Our sample comprised 201 frontline employees(female=31.84%;mean age=41.48 years,SD=7.97 years)in a Chinese coal enterprise,who completed surveys on innovation expectations of leaders,expected positive performance outcomes,innovative self-efficacy and innovative behavior.The results revealed that employees’expected positive performance outcomes mediated the positive relationship between leaders’innovation expectations and their innovative behavior.Employees’innovative self-efficacy positively moderated the relationship between their expected positive performance outcomes and innovative behavior,with this relationship being stronger for employees with high innovative self-efficacy.Moreover,we validated the moderated mediation model.Findings suggest that leaders can stimulate employee innovative behavior through expressing expectations and they also need to consider the boundary conditions. 展开更多
关键词 expectations of innovation expected positive performance outcomes innovative behavior innovative self-efficacy organizational innovation
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Innovative Food Processing Technologies Promoting Efficient Utilization of Nutrients in Staple Food Crops 被引量:1
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作者 Yi Yuan Xinyao Wei +13 位作者 Yuhong Mao Yuxue Zheng Ni He Yuan Guo Ming Wu Joseph Dumpler Bing Li Xu Chen Xixi Cai Jianping Wu Yongqi Tian Sihan Xie Jeyamkondan Subbiah Shaoyun Wang 《Engineering》 2025年第7期229-244,共16页
With the rapid growth of the global population and the increasing demand for healthier diets,improving the nutrient utilization efficiency of staple food crops has become a critical scientific and industrial chal-leng... With the rapid growth of the global population and the increasing demand for healthier diets,improving the nutrient utilization efficiency of staple food crops has become a critical scientific and industrial chal-lenge,prompting innovation in food processing technologies.This review introduces first the common nutritional challenges in the processing of staple food crops,followed by the comprehensive examination of research aiming to enhance the nutritional quality of staple food crop-based foods through innovative processing technologies,including microwave(MW),pulsed electric field(PEF),ultrasound,modern fer-mentation technology,and enzyme technology.Additionally,soybean processing is used as an example to underscore the importance of integrating innovative processing technologies for optimizing nutrient utilization in staple food crops.Although these innovative processing technologies have demonstrated a significant potential to improve nutrient utilization efficiency and enhance the overall nutritional pro-file of staple food crop-based food products,their current limitations must be acknowledged and addressed in future research.Fortunately,advancements in science and technology will facilitate pro-gress in food processing,enabling both the improvement of existing techniques as well as the develop-ment of entirely novel methodologies.This work aims to enhance the understanding of food practitioners on the way processing technologies may optimize nutrient utilization,thereby fostering innovation in food processing research and synergistic multi-technological strategies,ultimately providing valuable references to address global food security challenges. 展开更多
关键词 Staple food crops innovative food processing technologies Nutritional enhancement Nutrient utilization Antinutritional factors By-product utilization
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Exploration and Practice of Innovative Talent Cultivation Models for Master's Degree Students in Ethnic Medicine:A Case Study of Guangxi University of Chinese Medicine
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作者 Haicheng WEN Ting LIU +2 位作者 Chen LIN Wei WEI Hao CHENG 《Asian Agricultural Research》 2025年第10期45-49,共5页
The cultivation of innovative talents has become the primary objective of talent development in colleges and universities and is also essential for the personal development of master's degree students.Ethnic medic... The cultivation of innovative talents has become the primary objective of talent development in colleges and universities and is also essential for the personal development of master's degree students.Ethnic medicine,a key discipline at Guangxi University of Chinese Medicine,aims to cultivate high-level master's degree talents who possess comprehensive qualities,strong innovative capabilities,and distinctive characteristics of Zhuang medicine.This program is designed to better serve the local economic development and social needs of Guangxi,thereby promoting the substantive advancement of higher education within traditional medical institutions. 展开更多
关键词 ETHNIC MEDICINE innovative TALENT Master's DEGREE student Ability cultivation
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90%of women are unaware:Innovative trends and health risks in period products
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作者 Zhao Xinhua 《China Textile》 2025年第3期22-23,共2页
Innovation in the period product category has experienced a boost in recent years as part of the growing interest in women’s health products.Disruptive brands,start-ups and the area of Fem Tech are key areas to watch... Innovation in the period product category has experienced a boost in recent years as part of the growing interest in women’s health products.Disruptive brands,start-ups and the area of Fem Tech are key areas to watch.Collectively they are destigmatizing this category,and we can finally use the word“period”in marketing,as well as talking about the issues women deal with.Simultaneously,there has been an explosion in products in the sexual health category and a move away from outdated,reserved language. 展开更多
关键词 innovative trends period product innovation women s health products health risks destigmatizing fem tech start ups disruptive brands
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Exploring Industrialization Approaches for Innovative Development of Cosmetic Ingredients in China
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作者 Yao Yongbin 《China Detergent & Cosmetics》 2025年第2期6-11,共6页
As humanity advances at a rapid pace,both material wealth and spiritual fulfillment continue to grow and enrich our lives.“The remarkable year of 2025 marks a pinnacle in AI advancement,a quantum leap in robotics app... As humanity advances at a rapid pace,both material wealth and spiritual fulfillment continue to grow and enrich our lives.“The remarkable year of 2025 marks a pinnacle in AI advancement,a quantum leap in robotics applications,and groundbreaking progress in cosmic exploration.Even Nezha II(a Chinese animated blockbuster) brilliantly integrates technology,space,culture,and AI into its narrative.Yet,none of these developments can escape humanity's enduring obsession with facial aesthetics.As civilizations flourish across all dimensions,the beauty economy emerges as a formidable industrial force,driving mankind's relentless pursuit of a better life and a more beautiful future.” 展开更多
关键词 rapid pace spiritual fulfillment material wealth China AI advancement cosmic explorationeven cosmetic ingredients innovative development
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Preface to special issue on innovative techniques for railway infrastructure monitoring
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作者 Araliya Mosleh Diogo Ribeiro Abdollah Malekjafarian 《Railway Engineering Science》 2025年第4期521-521,共1页
Over the past few years,major investments have been directed toward building new railway lines and upgrading existing ones.Many of these lines include critical infrastructure where operational and safety conditions mu... Over the past few years,major investments have been directed toward building new railway lines and upgrading existing ones.Many of these lines include critical infrastructure where operational and safety conditions must be carefully considered throughout their life cycle.Recent advancements in science and technology have enabled more effective structural monitoring of railway systems,largely driven by the adoption of intelligent strategies for inspection,maintenance,monitoring,and risk management.Research continues to expand and deepen the knowledge in this area;however,it remains a challenging field due to factors such as the complexity of railway systems,the high cost of implementation,and the need for reliable long-term data. 展开更多
关键词 maintenance intelligent strategies innovative techniques structural monitoring INSPECTION critical infrastructure railway infrastructure monitoring operational safety conditions
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Innovative Mechanical Ventilation Control for Enhanced Indoor Air Quality and Energy Efficiency
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作者 Giovanni Miracco Francesco Nicoletti +1 位作者 Vittorio Ferraro Dimitrios Kaliakatsos 《Energy Engineering》 2025年第3期861-883,共23页
Indoor air quality(IAQ)is often overlooked,yet a poorly maintained environment can lead to significant health issues and reduced concentration and productivity in work or educational settings.This study presents an in... Indoor air quality(IAQ)is often overlooked,yet a poorly maintained environment can lead to significant health issues and reduced concentration and productivity in work or educational settings.This study presents an innovative control system for mechanical ventilation specifically designed for university classrooms,with the dual goal of enhancing IAQ and increasing energy efficiency.Two classrooms with distinct construction characteristics were analyzed:one with exterior walls and windows,and the other completely underground.For each classroom,a model was developed using DesignBuilder software,which was calibrated with experimental data regarding CO_(2) concentration,temperature,and relative humidity levels.The proposed ventilation system operates based on CO_(2) concentration,relative humidity,and potential for free heating and cooling.In addition,the analysis was conducted for other locations,demonstrating consistent energy savings across different climates and environments,always showing an annual reduction in energy consumption.Results demonstrate that mechanical ventilation,when integrated with heat recovery and free cooling strategies,significantly reduces energy consumption by up to 25%,while also maintaining optimal CO_(2) levels to enhance comfort and air quality.These findings emphasize the essential need for well-designed mechanical ventilation systems to ensure both psychophysical well-being and IAQ in enclosed spaces,particularly in environments intended for extended occupancy,such as classrooms.Furthermore,this approach has broad applicability,as it could be adapted to various building types,thereby contributing to sustainable energy management practices and promoting healthier indoor spaces.This study serves as a model for future designs aiming to balance energy efficiency with indoor air quality,especially relevant in the post-COVID era,where the importance of indoor air quality has become more widely recognized. 展开更多
关键词 Indoor air quality mechanical ventilation system innovative control system energy efficiency Energy-Plus simulation
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Research on the Cultivation of Top-notch Innovative Talents in Universities from the Perspective of the Integration of Education,Science and Technology,and Talent
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作者 Yue Zhang 《Journal of Contemporary Educational Research》 2025年第9期302-308,共7页
To better clarify the impact of the integration of education,science and technology,and talent on the cultivation of top-notch innovative talents in universities,this study adopts the fuzzy-set Qualitative Comparative... To better clarify the impact of the integration of education,science and technology,and talent on the cultivation of top-notch innovative talents in universities,this study adopts the fuzzy-set Qualitative Comparative Analysis(fsQCA)method.Using 23 universities in China as the research sample,the findings reveal that:(1)none of the three individual factors,education,science and technology,or talent can independently constitute either a necessary or sufficient condition for high-quality cultivation of top-notch innovative talents;(2)the sufficient condition for achieving high-quality cultivation lies in specific configurations of multiple condition variables;(3)five configurations were identified,from which three distinct paths toward achieving high-quality cultivation were derived.Accordingly,different universities can,based on their own resource endowments and local contexts,select appropriate cultivation paths to effectively enhance the quality of top-notch innovative talent training. 展开更多
关键词 Top-notch innovative talents Cultivation quality Education-science-talent integration Qualitative comparative analysis Configuration
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A Feast of the Amusement Industry,a New Starting Point for Innovative Development
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作者 Zhang Li Zhang Yue(图) 《China's Foreign Trade》 2025年第2期57-59,共3页
On March 21,2025,in Beijing,under the bright sunshine,the China International Exhibition Center(Shunyi Hal l)was bustling with act ivity.The 2025 China(Beijing)International Amusement Facilities and Equipment Expo off... On March 21,2025,in Beijing,under the bright sunshine,the China International Exhibition Center(Shunyi Hal l)was bustling with act ivity.The 2025 China(Beijing)International Amusement Facilities and Equipment Expo officially came to a close.At the exhibition site,the reporter saw many visitors eagerly taking their seats on amusement rides,their faces beaming with joy,as if they had instantly returned to their carefree childhood days. 展开更多
关键词 equipment expo China International Exhibition Center amusement facilities innovative development BEIJING
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An innovative external drainage device for suprachoroidal fluid: the puncture needle with drainage groove
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作者 Jing-Wen Hui Xiao-Li Li +2 位作者 Bo Xiao Quan-Hong Han Ying Wang 《International Journal of Ophthalmology(English edition)》 2025年第5期962-964,共3页
Dear Editor,We introduce a novel surgical instrument designed to overcome the challenges in draining fluid from the suprachoroidal space in patients with choroidal detachment.In the evolving landscape of ophthalmic su... Dear Editor,We introduce a novel surgical instrument designed to overcome the challenges in draining fluid from the suprachoroidal space in patients with choroidal detachment.In the evolving landscape of ophthalmic surgeries,procedures that were once considered complex,such as those for choroidal detachment,are becoming increasingly common.Drainage of subchoroidal fluid was derived from 1985[1]with indirect visualization during scleral buckle surgery[2-4]. 展开更多
关键词 surgical instrument scleral buckle surgery draining fluid innovative external drainage device choroidal detachmentare indirect visualization choroidal detachmentin subchoroidal fluid
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Research on the Mechanism Through Which the Classroom Environment Drives the Innovative Behavior of Medical Students:An Empirical Study Based on Medical Colleges in Sichuan Province
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作者 Li Chengxue Zhang Hongying 《Contemporary Social Sciences》 2025年第6期85-101,共17页
To explore the mechanism through which the classroom environment influences the innovative behavior of medical students,this research paper used a sample of 1,019 medical students from four medical colleges in Sichuan... To explore the mechanism through which the classroom environment influences the innovative behavior of medical students,this research paper used a sample of 1,019 medical students from four medical colleges in Sichuan province.The paper then constructed and tested an integrated model that employs classroom environment as the independent variable,innovative behavior as the dependent variable,creative self-efficacy as the mediator variable,and teachers’emotional support as the moderator variable.The results show that the classroom environment and its six dimensions are all significantly and positively correlated with innovative behavior and can also significantly and positively predict it;creative self-efficacy plays a partial mediating role in the relationship between the classroom environment and innovative behavior;the emotional support of teachers positively moderates the influence of three types of teacher-led environments-the teacher-student relationship,the teaching method,and equal attention-on medical students’innovative behavior.The research findings have deepened the understanding of the mechanism that underlies the innovative behavior of medical students and highlight the importance of psychological empowerment and contextualized support in the cultivation of innovative talents in medical education. 展开更多
关键词 classroom environment innovative behavior creative self-efficacy teachers’emotional support medical students
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Creating a New Future for Sino-Swiss Innovative Strategic Partnership
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作者 ZHOU LIN 《China Today》 2025年第6期54-56,共3页
Swiss Ambassador to China eyes promising areas for more cooperation with China.THIS year marks the 75th anniversary of the diplomatic relations between the People’s Republic of China and Switzerland.Since the two cou... Swiss Ambassador to China eyes promising areas for more cooperation with China.THIS year marks the 75th anniversary of the diplomatic relations between the People’s Republic of China and Switzerland.Since the two countries established an innovative strategic partnership in 2016,the bilateral ties have been hailed as a“model”in China’s relations with Western countries. 展开更多
关键词 diplomatic relations th anniversary Sino Swiss relations innovative strategic partnership strategic partnership cooperation model
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Innovative pathways to sustainable wheat production
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作者 Xiao Wang Xiangnan Li +1 位作者 Fulai Liu Dong Jiang 《Journal of Integrative Agriculture》 2025年第8期2885-2887,共3页
Wheat(Triticum aestivum L.)is a cornerstone of global food security,feeding over a third of the world’s population and functioning as a critical economic crop across diverse agroecological zones(FAO 2022).However,whe... Wheat(Triticum aestivum L.)is a cornerstone of global food security,feeding over a third of the world’s population and functioning as a critical economic crop across diverse agroecological zones(FAO 2022).However,wheat production faces mounting challenges from climate volatility,resource depletion,and the pressing demand for sustainable intensification. 展开更多
关键词 sustainable wheat production sustainable intensification climate volatility resource depletion Triticum aestivum L global food security innovative pathways
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Analysis of the Necessity for Higher Vocational Colleges to Conduct Scientific Research and Exploration of Innovative Pathways
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作者 Tingzhou Ning Yong Lyu 《Journal of Contemporary Educational Research》 2025年第9期57-67,共11页
As an integral part of China’s higher education system,higher vocational colleges play a significant role in talent cultivation,social services,and cultural inheritance.With the development of the times and the advan... As an integral part of China’s higher education system,higher vocational colleges play a significant role in talent cultivation,social services,and cultural inheritance.With the development of the times and the advancement of educational reform,the role of scientific research in higher vocational colleges has become increasingly prominent.This paper started from the necessity of conducting scientific research in higher vocational colleges,providing an in-depth analysis of its importance in improving teaching quality,promoting teachers’professional development,driving social services,and enhancing the college’s core competitiveness.At the same time,addressing the existing problems in current scientific research work at higher vocational colleges,this paper proposed innovative pathways focusing on the scientific research management system,scientific research team construction,scientific research funding investment,and scientific research outcome transformation.The aim is to provide valuable references for the scientific research development of higher vocational colleges. 展开更多
关键词 Higher vocational college Scientific research Necessity analysis Existing problem innovative pathway
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