With its product brands Oerlikon Barmag,Oerlikon Neumag and Oerlikon Nonwoven,Barmag is presenting itself at this year's ITMA Asia+CITME with innovations in yarn production that are above all one thing:productive ...With its product brands Oerlikon Barmag,Oerlikon Neumag and Oerlikon Nonwoven,Barmag is presenting itself at this year's ITMA Asia+CITME with innovations in yarn production that are above all one thing:productive and sustainable.展开更多
The automotive industry is under increasingscrutiny to improve sustainability,and one of thekey approaches to addressing this is sustainablematerial choice.As an industry,the automotivesector uses over l4 million tonn...The automotive industry is under increasingscrutiny to improve sustainability,and one of thekey approaches to addressing this is sustainablematerial choice.As an industry,the automotivesector uses over l4 million tonnes of plastics inpassenger automotive vehicles each year.展开更多
Context:In the dynamic and constantly evolving world of agriculture,promoting innovation and ensuring sustainable growth are crucial.A planned division of tasks and responsibilities within agricultural systems,known a...Context:In the dynamic and constantly evolving world of agriculture,promoting innovation and ensuring sustainable growth are crucial.A planned division of tasks and responsibilities within agricultural systems,known as efficient role allocation,is necessary to make this vision a reality.Climate-smart agriculture(CSA)movement enjoys widespread support from the research and development community because it seeks to improve livelihoods in response to climate change.Objective:This study explores an innovative approach to optimizing role assignment within agricultural frameworks to effectively scale AI-driven innovations.By leveraging advanced algorithms and machine learning techniques,the research aims to streamline the allocation of tasks and responsibilities among various stakeholders,including farmers,agronomists,technicians,and AI systems.Methods:The methodology involves the development of a dynamic role assignment model that considers factors such as expertise,resource availability,and real-time environmental data.This model is tested in various agricultural scenarios to evaluate its impact on operational efficiency and innovation scalability.The findings demonstrate that optimized role assignment not only enhances the performance of AI applications but also fosters a collaborative ecosystem that is adaptable to changing agricultural demands.Results:&Discussion:This research finds a number of elements that affect how well duties are distributed within agricultural frameworks,including organizational frameworks,leadership,resource accessibility,and cooperative efforts through AI.In addition to advocating for its comprehensive integration into the sector's culture,this paper offers a collection of best practices and techniques for optimizing role allocation in agriculture.Additionally,the study gives a thorough overview,summary,and analysis of a few papers that are specifically concerned with scaling innovation in the field of agricultural research for development.Significance:Furthermore,the study highlights the potential of AI to transform traditional farming practices,reduce labor-intensive processes,and improve decision-making accuracy.The proposed approach serves as a blueprint for agricultural enterprises aiming to adopt AI technologies while ensuring optimal utilization of human and technological resources.By addressing the challenges of role ambiguity and resource allocation,this research contributes to the broader goal of achieving sustainable and resilient agricultural systems through technological innovation.展开更多
Modern cardiopulmonary resuscitation(CPR)has been established for more than 60 years;however,its success rate remains low.Currently,the global incidence of out-of-hospital cardiac arrest(OHCA)is rising,ranging from 52...Modern cardiopulmonary resuscitation(CPR)has been established for more than 60 years;however,its success rate remains low.Currently,the global incidence of out-of-hospital cardiac arrest(OHCA)is rising,ranging from 52.5 to 97.1 per 100,000 population.[1,2]Survival-to-discharge rates for OHCA and in-hospital cardiac arrest(IHCA)are not satisfactory,with ranges of 1.2%-9.9%and 9.1%-19.1%,respectively.展开更多
The micro-drama No Trivial Matters in Xicheng was awarded the title of Outstanding Online Micro-drama for 2024 by the National Radio and Television Administration.By depicting how community workers address people'...The micro-drama No Trivial Matters in Xicheng was awarded the title of Outstanding Online Micro-drama for 2024 by the National Radio and Television Administration.By depicting how community workers address people's livelihood concerns such as housing,transportation,and elderly care,the drama vividly showcases the warmth and responsibility in urban grassroots governance.展开更多
In the wave of intelligent transformation in the textile printing and dyeing industry,Changzhou Hongda Intelligence Technology Co.,Ltd.stands as a leading enterprise specializing in online inspection equipment and int...In the wave of intelligent transformation in the textile printing and dyeing industry,Changzhou Hongda Intelligence Technology Co.,Ltd.stands as a leading enterprise specializing in online inspection equipment and intelligent digital production lines.The company boasts strong independent innovation capabilities and internationally advanced technologies.With core strengths rooted in a deep understanding and research of smart manufacturing for the industry,Hongda possesses cutting-edge expertise in machine vision,artificial intelligence,digital twin,and automation technologies.It leads the development of intelligent manufacturing in textile printing and dyeing and has become an industry benchmark.展开更多
Background:Head and neck cancers(HNC)account for a significant global health burden,with increasing incidence rates and complex treatment requirements.Traditional diagnostic and therapeutic approaches,while effective,...Background:Head and neck cancers(HNC)account for a significant global health burden,with increasing incidence rates and complex treatment requirements.Traditional diagnostic and therapeutic approaches,while effective,often result in substantial morbidity and limitations in personalized care.This review provides a comprehensive overview of the latest innovations in diagnostics and therapeutic strategies for HNC from 2015 to 2024.Methods:A review of literature focused on pe-reviewed journals,clinical trial databases,and oncology conference proceedings.Key areas include molecular diagnostics,imaging technologies,minimally invasive surgeries,and innovative therapeutic strategies.Results:Technologies like liquid biopsy next-generation sequencing(NGS)have greatly improved diagnostic accuracy and personalization in HNC care.These advancements have improved survival rates and enhanced patients’quality of life.Personalized therapeutic approaches,including immune checkpoint inhibitors,precision radiation therapy,and surgery,have led to enhanced treatment efficacy while reducing side effects.The integration of AI and machine learning into diagnostics and treatment planning shows promise in optimizing clinical decision-making and predicting treatment outcomes.Conclusion:The current innovations in diagnostics and therapeutics are reshaping the management of head and neck cancer,offering more tailored and effective approaches to care.Overall,the continuous integration of these innovations in clinical practice is reshaping HNC treatment and improving patient outcomes and survival rates.Future research should focus on further refining these technologies,addressing challenges related to accessibility,and exploring their long-term clinical benefits in diverse patient populations.展开更多
This editorial critically evaluated the recent study by AlMousa et al,which examined the impact of the Arabic version of the American Academy of Or-thopedic Surgeons Foot and Ankle Outcomes Questionnaire(AAOS-FAOQ)on ...This editorial critically evaluated the recent study by AlMousa et al,which examined the impact of the Arabic version of the American Academy of Or-thopedic Surgeons Foot and Ankle Outcomes Questionnaire(AAOS-FAOQ)on postoperative quality of life and recovery in Arabic-speaking patients with traumatic foot and ankle injuries.In the context of systemic linguistic exclusion in orthopedic research—where English-language journals dominated most publi-cations and non-English-speaking populations faced dual barriers of trial under-representation and semantic distortions(e.g.,mistranslations of terms like"joint instability"in Arabic)—AlMousa et al's work highlighted the transformative po-tential of culturally adapted methodologies.Their rigorous four-stage adaptation framework validated the Arabic AAOS-FAOQ as a reliable tool,enhancing ecological validity and reducing bias in patient-reported outcomes.However,limitations such as regional specificity(Gulf-centric sampling)and short follow-up periods(4 months)underscored broader challenges in non-English research:Redundant studies,prolonged hospital stays for limited English proficiency patients,and underrepresentation of certain ethnic groups in trials.To dismantle linguistic hegemony,we proposed semantic reconstruction(e.g.,integrating culturally specific indicators like"prayer posture"),dialect-aware neural tran-slation,and World Health Organization led terminology standardization.In line with these proposed solutions,AlMousa et al’s study exemplified how language-sensitive adaptations could bridge equity gaps,while future efforts would need to balance cultural specificity with cross-study comparability through AI-driven multilingual databases and policy mandates for cultural adaptation roadmaps.展开更多
As a response to the complexity of modern health care,nursing education is undergoing significant transformation.This paper aims to explore changing dynamics in nursing education,highlighting trends,challenges,and the...As a response to the complexity of modern health care,nursing education is undergoing significant transformation.This paper aims to explore changing dynamics in nursing education,highlighting trends,challenges,and the potential of Design-Based Research(DBR)as a methodological approach for curricular enhancement.This study employed a qualitative synthesis methodology was utilised,employing a systematic literature analysis of peer-reviewed articles published from 2019 to 2023.Relevant studies were searched in primary databases such as PubMed,Scopus,and Google Scholar,using specific keywords pertaining to nursing education,innovative pedagogical approaches,and DBR.The review revealed significant trends in nursing education including empathy and resilience,cultural competence,technology,interprofessional education,as well as competency-based approaches.Major challenges included teacher shortages,limited clinical placements,technological adaptability,and student mental health issues.DBR became an approach to address these challenges and offers an iterative model for curriculum development and educational innovation.DBR is a systematic and collaborative way to improve nursing education.Despite the barriers to implementation,DBR can lead to a more applicable curriculum based on real-world healthcare needs and create a nimbler educational process to prepare nursing graduates for working in complex healthcare environments.展开更多
The intertwined challenges of climate change, resource scarcity, and conflict require innovative integrated solutions that address both environmental and societal vulnerabilities. Technological innovation offers a tra...The intertwined challenges of climate change, resource scarcity, and conflict require innovative integrated solutions that address both environmental and societal vulnerabilities. Technological innovation offers a transformative pathway for climate change adaptation and peacebuilding, with emphasis on a holistic approach to managing resource conflicts and environmental challenges. This paper explores the synergies between emerging technologies and strategic framework to mitigate climate-induced tensions and foster resilience. It focuses on the application of renewable energy systems to reduce dependence on contested resources, blockchain technology to ensure transparency in climate finance, equitable resource allocation and Artificial Intelligence (AI) to enhance early warning systems for climate-related disaster and conflicts. Additionally, technologies such as precision agriculture and remote sensing empower communities to optimize resource use, adapt to shifting environmental conditions, and reduce competition over scares resources. These innovations with inclusive governance and local capacity-building are very primordial. Ultimately, the convergence of technology, policy, and local participation offers a scalable and replicable model for addressing the dual challenges of environmental degradation and instability, thereby paving the way for a more sustainable and peaceful future.展开更多
This paper offers a comprehensive overview of the operational principles of current therapeutic devices for diabetic foot management and further analyzes technological innovations and developmental trends,aiming to pr...This paper offers a comprehensive overview of the operational principles of current therapeutic devices for diabetic foot management and further analyzes technological innovations and developmental trends,aiming to promote research and development in the field of technological convergence.The ultimate goal is to enhance the cure rate for diabetic foot conditions and to decrease the incidence of amputations.The paper discusses the novel applications of ultrasound and optical therapeutic devices within the field of physiotherapy,the numerous advantages of chitosan dressings in biotechnology,the ongoing advancements and broader combined use of vacuum sealing drainage techniques,and the distinctive effects and innovations associated with micro-oxygen diffusion techniques.It thoroughly examines various technological mechanisms that facilitate wound healing,highlighting the clinical applications of ultrasonic atomized medicinal solutions,novel dressing graft copolymerization,continuous hypoxia diffusion,and the functions of vacuum drainage.These advancements facilitate the integration of drainage and dressing changes,with the potential to enhance the therapeutic effects of diabetic foot treatment and provide valuable insights for clinical application.展开更多
The micro-public opinion environment,characterized by information fragmentation,instantaneous dissemination,emotional contagion,and diverse values,has profoundly transformed the information acquisition patterns and co...The micro-public opinion environment,characterized by information fragmentation,instantaneous dissemination,emotional contagion,and diverse values,has profoundly transformed the information acquisition patterns and cognitive formation processes of college students.It also poses new challenges and opportunities for innovation in ideological and political education(hereinafter referred to as“IPE”)for college students.Starting from the contemporary value of IPE for college students,this paper analyzes the logical connection between the micro-public opinion environment and IPE,thoroughly examines the core challenges faced by IPE in this context,and proposes specific innovative paths from four perspectives:content,methods,subjects,and mechanisms.The aim is to provide insights for enhancing the pertinence and effectiveness of IPE for college students in the micro-public opinion environment.展开更多
Nine decades ago in 1933,Evarts A.Graham performed the first successful pneumonectomy in a patient with primary pulmonary squamous cell carcinoma.The patient survived for another 30 years,which drew the curtain on the...Nine decades ago in 1933,Evarts A.Graham performed the first successful pneumonectomy in a patient with primary pulmonary squamous cell carcinoma.The patient survived for another 30 years,which drew the curtain on the surgical treatment of lung cancer.Surgical resection continues to be the cornerstone of multidisciplinary treatment for patients with early-stage non-small cell lung cancer and a proportion of those with locally advanced disease.Moreover,recent years have seen developments in automatic control,biomechanics,robotics,image transmission,artificial intelligence,three-dimensional reconstruction and printing,biological pharmacy,and molecular biology.Therefore,there is now an increasing focus on how to integrate these technologies into lung cancer surgery to improve quality of life,resect the tumor accurately,expand the population that is suitable for surgical management,predict disease recurrence with better accuracy,and ultimately achieve long-term survival.This article systematically reviews the innovative achievements that may be detrimental to current clinical practice and in future clinical trials,and simultaneously provides a brief overview of the polyvagal perspective in this field.展开更多
Background: While global efforts have led to a decline in maternal and neonatal mortality, Sub-Saharan Africa continues to face disproportionately high rates, remaining far above the Sustainable Development Goal (SDG)...Background: While global efforts have led to a decline in maternal and neonatal mortality, Sub-Saharan Africa continues to face disproportionately high rates, remaining far above the Sustainable Development Goal (SDG) targets. In Kenya, as the 2030 SDG deadline approaches, the gap in maternal, neonatal, and child health services remains significant. Addressing these challenges is critical to improving Maternal, Neonatal, and Child Health (MNCH) outcomes. Objective: This study explores how integration of digital health innovations into the MNCH chain of service delivery affects the quality of MNCH care within the selected PHC settings in Kajiado, Kisii and Migori Counties in Kenya. Methodology: This Quasi-experimental study was conducted 1-year post-intervention targeting a total of 482 pregnant women from intervention and control sites in Kisii, Kajiado and Migori Counties, Kenya. Data was analysed using Chi-Square test comparing frequencies between intervention and control groups when both variables are categorical. Results: Pre-intervention data revealed an increase in first ANC coverage within first trimester, from 167 to 278 post-intervention (p Linda mama social health insurance registrations increased from 1008 to 1135. At the intervention sites, 938 pregnant women got screened by midwives using portable mobile Obstetric Point-of-Care Ultrasound (OPOCUS) technology compared to the 27 cases that accessed ultrasound services in the noncontiguous control sites. The pilot sites midwives earned themselves an incentive income totaling Ksh 400,000 while the Community Health Promoters (CHPs) who created demand for OPOCUS earned an incentive income totaling Ksh 327,195 from their IGAs that were project supported. There was a significant increase in mobile health application usage and e-resources access for health information in the intervention group (p services and improved adherence to referrals. Conclusion: The success of digital health interventions in improving health-seeking behaviour, knowledge, and service uptake highlights the potential of such innovations to strengthen health systems and achieve universal health coverage. We recommend the intervention for a scale-up in other PHC settings in Kenya.展开更多
This comparative review explores the dynamic and evolving landscape of artificial intelligence(AI)-powered innovations within high-tech research and development(R&D).It delves into both theoreticalmodels and pract...This comparative review explores the dynamic and evolving landscape of artificial intelligence(AI)-powered innovations within high-tech research and development(R&D).It delves into both theoreticalmodels and practical applications across a broad range of industries,including biotechnology,automotive,aerospace,and telecom-munications.By examining critical advancements in AI algorithms,machine learning,deep learning models,simulations,and predictive analytics,the review underscores the transformative role AI has played in advancing theoretical research and shaping cutting-edge technologies.The review integrates both qualitative and quantitative data derived from academic studies,industry reports,and real-world case studies to showcase the tangible impacts of AI on product innovation,process optimization,and strategic decision-making.Notably,it discusses the challenges of integrating AI within complex industrial systems,such as ethical concerns,technical limitations,and the need for regulatory oversight.The findings reveal a mixed landscape where AI has significantly accelerated R&D processes,reduced costs,and enabled more precise simulations and predictions,but also highlighted gaps in knowledge transfer,skills adaptation,and cross-industry standardization.By bridging the gap between AI theory and practice,the review offers insights into the effectiveness,successes,and obstacles faced by organizations as they implement AI-driven solutions.Concluding with a forward-looking perspective,the review identifies emerging trends,future challenges,and promising opportunities inAI-poweredR&D,such as the rise of autonomous systems,AI-driven drug discovery,and sustainable energy solutions.It offers a holistic understanding of how AI is shaping the future of technological innovation and provides actionable insights for researchers,engineers,and policymakers involved in high-tech Research and Development(R&D).展开更多
This review explores the evolution of the textile handicraft industry in Saudi Arabia, emphasizing its cultural and economic significance. The study highlights the transition from traditional practices to modern innov...This review explores the evolution of the textile handicraft industry in Saudi Arabia, emphasizing its cultural and economic significance. The study highlights the transition from traditional practices to modern innovations and examines the impact of globalization and technological advancements on the industry. Key innovations are discussed, demonstrating their role in enhancing textile production while preserving cultural heritage. Major challenges, such as competition from industrial textiles and the need for sustainable practices, are identified. Opportunities for growth are explored, including leveraging tourism and international markets to promote Saudi handicrafts. The social and cultural impacts of the sector are underscored, particularly in sustaining community traditions and providing economic opportunities for artisans. Strategic recommendations for supporting and advancing the industry are offered, ensuring its continued relevance and sustainability in a rapidly changing global market. This analysis provides a robust framework for understanding the current state and future potential of Saudi Arabia’s textile handicraft industry.展开更多
The introduction of laparoscopy is an example of surgical innovation with a rapid implementation in many areas of surgery. A large number of controlled studiesand meta-analyses have shown that laparoscopic colorectal ...The introduction of laparoscopy is an example of surgical innovation with a rapid implementation in many areas of surgery. A large number of controlled studiesand meta-analyses have shown that laparoscopic colorectal surgery is associated with the same benefits than other minimally invasive procedures, including lesser pain, earlier recovery of bowel transit and shorter hospital stay. On the other hand, despite initial concerns about oncological safety, well-designed prospective randomized multicentre trials have demonstrated that oncological outcomes of laparoscopy and open surgery are similar. Although the use of laparoscopy in colorectal surgery has increased in recent years, the percentages of patients treated with surgery using minimally invasive techniques are still reduced and there are also substantial differences among centres. It has been argued that the limiting factor for the use of laparoscopic procedures is the number of surgeons with adequate skills to perform a laparoscopic colectomy rather than the tumour of patients' characteristics. In this regard, future efforts to increase the use of laparoscopic techniques in colorectal surgery will necessarily require more efforts in teaching surgeons. We here present a review of recent controversies of the use of laparoscopy in colorectal surgery, such as in rectal cancer operations, the possibility of reproducing complete mesocolon excision, and the benefits of intracorporeal anastomosis after right hemicolectomy. We also describe the results of latest innovations such as single incision laparoscopic surgery, robotic surgery and natural orifice transluminal endoscopic surgery for colon and rectal diseases.展开更多
Up to a quarter of polyps and adenomas are missed during colonoscopy due to poor visualization behind folds and the inner curves of flexures, and the presence of flat lesions that are difficult to detect. These number...Up to a quarter of polyps and adenomas are missed during colonoscopy due to poor visualization behind folds and the inner curves of flexures, and the presence of flat lesions that are difficult to detect. These numbers may however be conservative because they mainly come from back-to-back studies performed with standard colonoscopes, which are unable to visualize the entire mucosal surface. In the past several years, new endoscopic techniques have been introduced to improve the detection of polyps and adenomas. The introduction of high definition colonoscopes and visual image enhancement technologies have been suggested to lead to better recognition of flat and small lesions, but the absolute increase in diagnostic yield seems limited. Cap assisted colonoscopy and water-exchange colonoscopy are methods to facilitate cecal intubation and increase patients comfort, but show only a marginal or no benefit on polyp and adenoma detection. Retroflexion is routinely used in the rectum for the inspection of the dentate line, but withdrawal in retroflexion in the colon is in general not recommended due to the risk of perforation. In contrast, colonoscopy with the Third-Eye Retroscope<sup>®</sup> may result in considerable lower miss rates compared to standard colonoscopy, but this technique is not practical in case of polypectomy and is more time consuming. The recently introduced Full Spectrum Endoscopy™ colonoscopes maintains the technical capabilities of standard colonoscopes and provides a much wider view of 330 degrees compared to the 170 degrees with standard colonoscopes. Remarkable lower adenoma miss rates with this new technique were recently demonstrated in the first randomized study. Nonetheless, more studies are required to determine the exact additional diagnostic yield in clinical practice. Optimizing the efficacy of colorectal cancer screening and surveillance requires high definition colonoscopes with improved virtual chromoendoscopy technology that visualize the whole colon mucosa while maintaining optimal washing, suction and therapeutic capabilities, and keeping the procedural time as low and patient discomfort as optimal as possible.展开更多
文摘With its product brands Oerlikon Barmag,Oerlikon Neumag and Oerlikon Nonwoven,Barmag is presenting itself at this year's ITMA Asia+CITME with innovations in yarn production that are above all one thing:productive and sustainable.
文摘The automotive industry is under increasingscrutiny to improve sustainability,and one of thekey approaches to addressing this is sustainablematerial choice.As an industry,the automotivesector uses over l4 million tonnes of plastics inpassenger automotive vehicles each year.
文摘Context:In the dynamic and constantly evolving world of agriculture,promoting innovation and ensuring sustainable growth are crucial.A planned division of tasks and responsibilities within agricultural systems,known as efficient role allocation,is necessary to make this vision a reality.Climate-smart agriculture(CSA)movement enjoys widespread support from the research and development community because it seeks to improve livelihoods in response to climate change.Objective:This study explores an innovative approach to optimizing role assignment within agricultural frameworks to effectively scale AI-driven innovations.By leveraging advanced algorithms and machine learning techniques,the research aims to streamline the allocation of tasks and responsibilities among various stakeholders,including farmers,agronomists,technicians,and AI systems.Methods:The methodology involves the development of a dynamic role assignment model that considers factors such as expertise,resource availability,and real-time environmental data.This model is tested in various agricultural scenarios to evaluate its impact on operational efficiency and innovation scalability.The findings demonstrate that optimized role assignment not only enhances the performance of AI applications but also fosters a collaborative ecosystem that is adaptable to changing agricultural demands.Results:&Discussion:This research finds a number of elements that affect how well duties are distributed within agricultural frameworks,including organizational frameworks,leadership,resource accessibility,and cooperative efforts through AI.In addition to advocating for its comprehensive integration into the sector's culture,this paper offers a collection of best practices and techniques for optimizing role allocation in agriculture.Additionally,the study gives a thorough overview,summary,and analysis of a few papers that are specifically concerned with scaling innovation in the field of agricultural research for development.Significance:Furthermore,the study highlights the potential of AI to transform traditional farming practices,reduce labor-intensive processes,and improve decision-making accuracy.The proposed approach serves as a blueprint for agricultural enterprises aiming to adopt AI technologies while ensuring optimal utilization of human and technological resources.By addressing the challenges of role ambiguity and resource allocation,this research contributes to the broader goal of achieving sustainable and resilient agricultural systems through technological innovation.
文摘Modern cardiopulmonary resuscitation(CPR)has been established for more than 60 years;however,its success rate remains low.Currently,the global incidence of out-of-hospital cardiac arrest(OHCA)is rising,ranging from 52.5 to 97.1 per 100,000 population.[1,2]Survival-to-discharge rates for OHCA and in-hospital cardiac arrest(IHCA)are not satisfactory,with ranges of 1.2%-9.9%and 9.1%-19.1%,respectively.
文摘The micro-drama No Trivial Matters in Xicheng was awarded the title of Outstanding Online Micro-drama for 2024 by the National Radio and Television Administration.By depicting how community workers address people's livelihood concerns such as housing,transportation,and elderly care,the drama vividly showcases the warmth and responsibility in urban grassroots governance.
文摘In the wave of intelligent transformation in the textile printing and dyeing industry,Changzhou Hongda Intelligence Technology Co.,Ltd.stands as a leading enterprise specializing in online inspection equipment and intelligent digital production lines.The company boasts strong independent innovation capabilities and internationally advanced technologies.With core strengths rooted in a deep understanding and research of smart manufacturing for the industry,Hongda possesses cutting-edge expertise in machine vision,artificial intelligence,digital twin,and automation technologies.It leads the development of intelligent manufacturing in textile printing and dyeing and has become an industry benchmark.
文摘Background:Head and neck cancers(HNC)account for a significant global health burden,with increasing incidence rates and complex treatment requirements.Traditional diagnostic and therapeutic approaches,while effective,often result in substantial morbidity and limitations in personalized care.This review provides a comprehensive overview of the latest innovations in diagnostics and therapeutic strategies for HNC from 2015 to 2024.Methods:A review of literature focused on pe-reviewed journals,clinical trial databases,and oncology conference proceedings.Key areas include molecular diagnostics,imaging technologies,minimally invasive surgeries,and innovative therapeutic strategies.Results:Technologies like liquid biopsy next-generation sequencing(NGS)have greatly improved diagnostic accuracy and personalization in HNC care.These advancements have improved survival rates and enhanced patients’quality of life.Personalized therapeutic approaches,including immune checkpoint inhibitors,precision radiation therapy,and surgery,have led to enhanced treatment efficacy while reducing side effects.The integration of AI and machine learning into diagnostics and treatment planning shows promise in optimizing clinical decision-making and predicting treatment outcomes.Conclusion:The current innovations in diagnostics and therapeutics are reshaping the management of head and neck cancer,offering more tailored and effective approaches to care.Overall,the continuous integration of these innovations in clinical practice is reshaping HNC treatment and improving patient outcomes and survival rates.Future research should focus on further refining these technologies,addressing challenges related to accessibility,and exploring their long-term clinical benefits in diverse patient populations.
文摘This editorial critically evaluated the recent study by AlMousa et al,which examined the impact of the Arabic version of the American Academy of Or-thopedic Surgeons Foot and Ankle Outcomes Questionnaire(AAOS-FAOQ)on postoperative quality of life and recovery in Arabic-speaking patients with traumatic foot and ankle injuries.In the context of systemic linguistic exclusion in orthopedic research—where English-language journals dominated most publi-cations and non-English-speaking populations faced dual barriers of trial under-representation and semantic distortions(e.g.,mistranslations of terms like"joint instability"in Arabic)—AlMousa et al's work highlighted the transformative po-tential of culturally adapted methodologies.Their rigorous four-stage adaptation framework validated the Arabic AAOS-FAOQ as a reliable tool,enhancing ecological validity and reducing bias in patient-reported outcomes.However,limitations such as regional specificity(Gulf-centric sampling)and short follow-up periods(4 months)underscored broader challenges in non-English research:Redundant studies,prolonged hospital stays for limited English proficiency patients,and underrepresentation of certain ethnic groups in trials.To dismantle linguistic hegemony,we proposed semantic reconstruction(e.g.,integrating culturally specific indicators like"prayer posture"),dialect-aware neural tran-slation,and World Health Organization led terminology standardization.In line with these proposed solutions,AlMousa et al’s study exemplified how language-sensitive adaptations could bridge equity gaps,while future efforts would need to balance cultural specificity with cross-study comparability through AI-driven multilingual databases and policy mandates for cultural adaptation roadmaps.
文摘As a response to the complexity of modern health care,nursing education is undergoing significant transformation.This paper aims to explore changing dynamics in nursing education,highlighting trends,challenges,and the potential of Design-Based Research(DBR)as a methodological approach for curricular enhancement.This study employed a qualitative synthesis methodology was utilised,employing a systematic literature analysis of peer-reviewed articles published from 2019 to 2023.Relevant studies were searched in primary databases such as PubMed,Scopus,and Google Scholar,using specific keywords pertaining to nursing education,innovative pedagogical approaches,and DBR.The review revealed significant trends in nursing education including empathy and resilience,cultural competence,technology,interprofessional education,as well as competency-based approaches.Major challenges included teacher shortages,limited clinical placements,technological adaptability,and student mental health issues.DBR became an approach to address these challenges and offers an iterative model for curriculum development and educational innovation.DBR is a systematic and collaborative way to improve nursing education.Despite the barriers to implementation,DBR can lead to a more applicable curriculum based on real-world healthcare needs and create a nimbler educational process to prepare nursing graduates for working in complex healthcare environments.
文摘The intertwined challenges of climate change, resource scarcity, and conflict require innovative integrated solutions that address both environmental and societal vulnerabilities. Technological innovation offers a transformative pathway for climate change adaptation and peacebuilding, with emphasis on a holistic approach to managing resource conflicts and environmental challenges. This paper explores the synergies between emerging technologies and strategic framework to mitigate climate-induced tensions and foster resilience. It focuses on the application of renewable energy systems to reduce dependence on contested resources, blockchain technology to ensure transparency in climate finance, equitable resource allocation and Artificial Intelligence (AI) to enhance early warning systems for climate-related disaster and conflicts. Additionally, technologies such as precision agriculture and remote sensing empower communities to optimize resource use, adapt to shifting environmental conditions, and reduce competition over scares resources. These innovations with inclusive governance and local capacity-building are very primordial. Ultimately, the convergence of technology, policy, and local participation offers a scalable and replicable model for addressing the dual challenges of environmental degradation and instability, thereby paving the way for a more sustainable and peaceful future.
基金Supported by Undergraduate Innovation and Entrepreneurship Training Program(S202410599085).
文摘This paper offers a comprehensive overview of the operational principles of current therapeutic devices for diabetic foot management and further analyzes technological innovations and developmental trends,aiming to promote research and development in the field of technological convergence.The ultimate goal is to enhance the cure rate for diabetic foot conditions and to decrease the incidence of amputations.The paper discusses the novel applications of ultrasound and optical therapeutic devices within the field of physiotherapy,the numerous advantages of chitosan dressings in biotechnology,the ongoing advancements and broader combined use of vacuum sealing drainage techniques,and the distinctive effects and innovations associated with micro-oxygen diffusion techniques.It thoroughly examines various technological mechanisms that facilitate wound healing,highlighting the clinical applications of ultrasonic atomized medicinal solutions,novel dressing graft copolymerization,continuous hypoxia diffusion,and the functions of vacuum drainage.These advancements facilitate the integration of drainage and dressing changes,with the potential to enhance the therapeutic effects of diabetic foot treatment and provide valuable insights for clinical application.
文摘The micro-public opinion environment,characterized by information fragmentation,instantaneous dissemination,emotional contagion,and diverse values,has profoundly transformed the information acquisition patterns and cognitive formation processes of college students.It also poses new challenges and opportunities for innovation in ideological and political education(hereinafter referred to as“IPE”)for college students.Starting from the contemporary value of IPE for college students,this paper analyzes the logical connection between the micro-public opinion environment and IPE,thoroughly examines the core challenges faced by IPE in this context,and proposes specific innovative paths from four perspectives:content,methods,subjects,and mechanisms.The aim is to provide insights for enhancing the pertinence and effectiveness of IPE for college students in the micro-public opinion environment.
基金supported by grants from the Shenzhen Key Medical Discipline Construction Fund(number SZXK075)the Sanming Project of Medicine in Shenzhen(number SZSM201612097)the National Center/National Clinical Research Center for Cancer/Cancer Hospital&Shenzhen Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Shenzhen(number E010322008).
文摘Nine decades ago in 1933,Evarts A.Graham performed the first successful pneumonectomy in a patient with primary pulmonary squamous cell carcinoma.The patient survived for another 30 years,which drew the curtain on the surgical treatment of lung cancer.Surgical resection continues to be the cornerstone of multidisciplinary treatment for patients with early-stage non-small cell lung cancer and a proportion of those with locally advanced disease.Moreover,recent years have seen developments in automatic control,biomechanics,robotics,image transmission,artificial intelligence,three-dimensional reconstruction and printing,biological pharmacy,and molecular biology.Therefore,there is now an increasing focus on how to integrate these technologies into lung cancer surgery to improve quality of life,resect the tumor accurately,expand the population that is suitable for surgical management,predict disease recurrence with better accuracy,and ultimately achieve long-term survival.This article systematically reviews the innovative achievements that may be detrimental to current clinical practice and in future clinical trials,and simultaneously provides a brief overview of the polyvagal perspective in this field.
文摘Background: While global efforts have led to a decline in maternal and neonatal mortality, Sub-Saharan Africa continues to face disproportionately high rates, remaining far above the Sustainable Development Goal (SDG) targets. In Kenya, as the 2030 SDG deadline approaches, the gap in maternal, neonatal, and child health services remains significant. Addressing these challenges is critical to improving Maternal, Neonatal, and Child Health (MNCH) outcomes. Objective: This study explores how integration of digital health innovations into the MNCH chain of service delivery affects the quality of MNCH care within the selected PHC settings in Kajiado, Kisii and Migori Counties in Kenya. Methodology: This Quasi-experimental study was conducted 1-year post-intervention targeting a total of 482 pregnant women from intervention and control sites in Kisii, Kajiado and Migori Counties, Kenya. Data was analysed using Chi-Square test comparing frequencies between intervention and control groups when both variables are categorical. Results: Pre-intervention data revealed an increase in first ANC coverage within first trimester, from 167 to 278 post-intervention (p Linda mama social health insurance registrations increased from 1008 to 1135. At the intervention sites, 938 pregnant women got screened by midwives using portable mobile Obstetric Point-of-Care Ultrasound (OPOCUS) technology compared to the 27 cases that accessed ultrasound services in the noncontiguous control sites. The pilot sites midwives earned themselves an incentive income totaling Ksh 400,000 while the Community Health Promoters (CHPs) who created demand for OPOCUS earned an incentive income totaling Ksh 327,195 from their IGAs that were project supported. There was a significant increase in mobile health application usage and e-resources access for health information in the intervention group (p services and improved adherence to referrals. Conclusion: The success of digital health interventions in improving health-seeking behaviour, knowledge, and service uptake highlights the potential of such innovations to strengthen health systems and achieve universal health coverage. We recommend the intervention for a scale-up in other PHC settings in Kenya.
文摘This comparative review explores the dynamic and evolving landscape of artificial intelligence(AI)-powered innovations within high-tech research and development(R&D).It delves into both theoreticalmodels and practical applications across a broad range of industries,including biotechnology,automotive,aerospace,and telecom-munications.By examining critical advancements in AI algorithms,machine learning,deep learning models,simulations,and predictive analytics,the review underscores the transformative role AI has played in advancing theoretical research and shaping cutting-edge technologies.The review integrates both qualitative and quantitative data derived from academic studies,industry reports,and real-world case studies to showcase the tangible impacts of AI on product innovation,process optimization,and strategic decision-making.Notably,it discusses the challenges of integrating AI within complex industrial systems,such as ethical concerns,technical limitations,and the need for regulatory oversight.The findings reveal a mixed landscape where AI has significantly accelerated R&D processes,reduced costs,and enabled more precise simulations and predictions,but also highlighted gaps in knowledge transfer,skills adaptation,and cross-industry standardization.By bridging the gap between AI theory and practice,the review offers insights into the effectiveness,successes,and obstacles faced by organizations as they implement AI-driven solutions.Concluding with a forward-looking perspective,the review identifies emerging trends,future challenges,and promising opportunities inAI-poweredR&D,such as the rise of autonomous systems,AI-driven drug discovery,and sustainable energy solutions.It offers a holistic understanding of how AI is shaping the future of technological innovation and provides actionable insights for researchers,engineers,and policymakers involved in high-tech Research and Development(R&D).
文摘This review explores the evolution of the textile handicraft industry in Saudi Arabia, emphasizing its cultural and economic significance. The study highlights the transition from traditional practices to modern innovations and examines the impact of globalization and technological advancements on the industry. Key innovations are discussed, demonstrating their role in enhancing textile production while preserving cultural heritage. Major challenges, such as competition from industrial textiles and the need for sustainable practices, are identified. Opportunities for growth are explored, including leveraging tourism and international markets to promote Saudi handicrafts. The social and cultural impacts of the sector are underscored, particularly in sustaining community traditions and providing economic opportunities for artisans. Strategic recommendations for supporting and advancing the industry are offered, ensuring its continued relevance and sustainability in a rapidly changing global market. This analysis provides a robust framework for understanding the current state and future potential of Saudi Arabia’s textile handicraft industry.
文摘The introduction of laparoscopy is an example of surgical innovation with a rapid implementation in many areas of surgery. A large number of controlled studiesand meta-analyses have shown that laparoscopic colorectal surgery is associated with the same benefits than other minimally invasive procedures, including lesser pain, earlier recovery of bowel transit and shorter hospital stay. On the other hand, despite initial concerns about oncological safety, well-designed prospective randomized multicentre trials have demonstrated that oncological outcomes of laparoscopy and open surgery are similar. Although the use of laparoscopy in colorectal surgery has increased in recent years, the percentages of patients treated with surgery using minimally invasive techniques are still reduced and there are also substantial differences among centres. It has been argued that the limiting factor for the use of laparoscopic procedures is the number of surgeons with adequate skills to perform a laparoscopic colectomy rather than the tumour of patients' characteristics. In this regard, future efforts to increase the use of laparoscopic techniques in colorectal surgery will necessarily require more efforts in teaching surgeons. We here present a review of recent controversies of the use of laparoscopy in colorectal surgery, such as in rectal cancer operations, the possibility of reproducing complete mesocolon excision, and the benefits of intracorporeal anastomosis after right hemicolectomy. We also describe the results of latest innovations such as single incision laparoscopic surgery, robotic surgery and natural orifice transluminal endoscopic surgery for colon and rectal diseases.
文摘Up to a quarter of polyps and adenomas are missed during colonoscopy due to poor visualization behind folds and the inner curves of flexures, and the presence of flat lesions that are difficult to detect. These numbers may however be conservative because they mainly come from back-to-back studies performed with standard colonoscopes, which are unable to visualize the entire mucosal surface. In the past several years, new endoscopic techniques have been introduced to improve the detection of polyps and adenomas. The introduction of high definition colonoscopes and visual image enhancement technologies have been suggested to lead to better recognition of flat and small lesions, but the absolute increase in diagnostic yield seems limited. Cap assisted colonoscopy and water-exchange colonoscopy are methods to facilitate cecal intubation and increase patients comfort, but show only a marginal or no benefit on polyp and adenoma detection. Retroflexion is routinely used in the rectum for the inspection of the dentate line, but withdrawal in retroflexion in the colon is in general not recommended due to the risk of perforation. In contrast, colonoscopy with the Third-Eye Retroscope<sup>®</sup> may result in considerable lower miss rates compared to standard colonoscopy, but this technique is not practical in case of polypectomy and is more time consuming. The recently introduced Full Spectrum Endoscopy™ colonoscopes maintains the technical capabilities of standard colonoscopes and provides a much wider view of 330 degrees compared to the 170 degrees with standard colonoscopes. Remarkable lower adenoma miss rates with this new technique were recently demonstrated in the first randomized study. Nonetheless, more studies are required to determine the exact additional diagnostic yield in clinical practice. Optimizing the efficacy of colorectal cancer screening and surveillance requires high definition colonoscopes with improved virtual chromoendoscopy technology that visualize the whole colon mucosa while maintaining optimal washing, suction and therapeutic capabilities, and keeping the procedural time as low and patient discomfort as optimal as possible.
