AIM：To provide a side-by-side analysis of the summary of safety and effectiveness data（SSED）submitted to the FDA for the KAMRA and Raindrop corneal inlays for the correction of presbyopia.METHODS：SSED reports subm...AIM：To provide a side-by-side analysis of the summary of safety and effectiveness data（SSED）submitted to the FDA for the KAMRA and Raindrop corneal inlays for the correction of presbyopia.METHODS：SSED reports submitted to the FDA for KAMRA and Raindrop were compared with respect to loss of corrected distance visual acuity（CDVA）,adverse event rates,induction of astigmatism,retention of contrast sensitivity,stability of manifest refractive spherical equivalent（MRSE）,and achieved monocular uncorrected near visual acuity（UNVA）at 24mo.RESULTS：Totally 442/508 of KAMRA patients and344/373 Raindrop patients remained enrolled in the clinical trials at 24mo.The proportion of KAMRA and Raindrop patients who lost≥2 lines of CDVA at 24mo was 3.4%and1%,respectively.The adverse event rate was comparable between the devices.No significant inductions of astigmatism were noted.Both technologies induced a transient myopic shift in MRSE followed by a hyperopic shift and subsequent stabilization.Totally 87%of KAMRA and 98%of Raindrop patients attained a monocular UNVA of J5（20/40）or better at 24mo,28%of KAMRA and 67%of Raindrop patients attained a monocular UNVA of J1（20/20）or better at 24mo.CONCLUSION：Both devices can be considered safe and effective,however,the results of corneal inlay implantation are mixed,and long-term patient satisfaction will likely depend on subjective expectations about the capabilities of the inlays.Variability in surgical technique and postoperative care within and between the two clinical trials diminishes the comparative power of this article.展开更多
Corneal inlays and onlays represent a means of providing patients with permanent refractive error correction. As an alternative to conventional spectacles and contact lens, these techniques are less invasive compared ...Corneal inlays and onlays represent a means of providing patients with permanent refractive error correction. As an alternative to conventional spectacles and contact lens, these techniques are less invasive compared with laser-based refractive surgery and are reversible. In this review, we provide a brief overview of the anatomic microstructure of the human cornea, indicating the primary physiological function for each component. Next, the wide range of biomaterials used as corneal inlays and onlays are considered, from synthetic polymers to biological components derived from the extracellular matrix. The limitations and challenges associated with the most common materials are discussed as is the need to improve their properties to achieve long-term, complication-free intraocular implantation. Finally, the prospect of applying tissue engineering strategies is noted for its potential to generate autologous corneal tissue that could be implanted as the optimal inlay or onlay materials.展开更多
The art of polychrome lacquer painting with gold tracing and inlay represents the culmination of traditional Chinese lacquer craftsmanship.It integrates four core techniques-lacquer application,polychrome painting,gol...The art of polychrome lacquer painting with gold tracing and inlay represents the culmination of traditional Chinese lacquer craftsmanship.It integrates four core techniques-lacquer application,polychrome painting,gold tracing,and inlay-embodying the pinnacle of ancient artisan ingenuity.This paper begins by outlining the historical origins,technical characteristics,and cultural significance of this art form.Subsequently,using a Qing Dynasty“Hanging Screen Inlaid with Boxwood and Coral Depicting the Scene of Sudhana Paying Homage to Guanyin,with Polychrome Lacquer Painting and Gold Tracing”as a case study,it offers an in-depth analysis of its craftsmanship,visual elements,thematic narrative,and cultural connotations.The study aims to unveil its artistic value and contemporary relevance as a form of“living cultural heritage.”展开更多
The Chinese incense burner,a cornerstone of material culture,embodies distinguished craftsmanship and reflects sociocultural evolution across ritual,religious,and domestic life.Through analysis of a Qing-dynasty coppe...The Chinese incense burner,a cornerstone of material culture,embodies distinguished craftsmanship and reflects sociocultural evolution across ritual,religious,and domestic life.Through analysis of a Qing-dynasty copper Ding-style censer with gold and silver inlay,this paper examines its antique form,masterly technique,and decorative motifs.It demonstrates how such objects synthesize the cultural ethos of the Kang-Qian era by uniting Ming-Song literati classicism with consummate imperial artistry.This case study thus provides a focused lens on the critical interplay between elite taste and technical execution in the history of Chinese craftsmanship.展开更多
Objective: A new indirect composite restorative system with water combingpressure, light, and heat was introduced for the fabrication of inlays and onlays. Methods: Fifteendefected teeth were selected for composite re...Objective: A new indirect composite restorative system with water combingpressure, light, and heat was introduced for the fabrication of inlays and onlays. Methods: Fifteendefected teeth were selected for composite resin inlay and onlay fabrication with Tescera ATL unitequipment. The clinical trial was carried out for 3 months. Results: After 3 months test, 7parameters were checked, 15 Tescera inlays and onlays were demonstrated that exceptional esthetics,all 7 parameters were good and the patients were very satisfied. Conclusion: inlays , which weremade with Tescera ATL restorative system, are esthetics; physical properties of materials areimproved highly, and have a long-lasting durability. This restorative system is worthy to be usedand further studied in dental practice.展开更多
A reliability of flip-chip bonded die as a function of anisotropic conductive paste (ACP) hybrid materials, bonding conditions, and antenna pattern materials was investigated during the assembly of radio frequency ide...A reliability of flip-chip bonded die as a function of anisotropic conductive paste (ACP) hybrid materials, bonding conditions, and antenna pattern materials was investigated during the assembly of radio frequency identification(RFID) inlay. The optimization condition for flip-chip bonding was determined from the behavior of bonding strength. Under the optimized condition, the shear strength for the antenna printed with paste-type Ag ink was larger than that for Cu antenna. Furthermore, an identification distance was varied from the antenna materials. Comparing with the Ag antenna pattern, the as-bonded die on Cu antenna showed a larger distance of identification. However, the long-term reliability of inlay using the Cu antenna was decreased significantly as a function of aging time at room temperature because of the bended shape of Cu antenna formed during the flip-chip bonding process.展开更多
The purpose of this study was to demonstrate the improvement of hip joint dysregulation, including pain (coxalgia), tension, and restriction of joint mobility, using a dental gold alloy inlay. The subject was a 63-yea...The purpose of this study was to demonstrate the improvement of hip joint dysregulation, including pain (coxalgia), tension, and restriction of joint mobility, using a dental gold alloy inlay. The subject was a 63-year-old man who was suffering from the abovementioned symptoms for several months. On placement of the gold alloy inlay on his chest, the joint flexibility was observed to increase, and the severity of the abovementioned symptoms decreased. When the inlay was placed in his tooth, the flexibility of the joint further increased, and all other symptoms disappeared. No side effects were observed, and the prognosis was good. We believe that these effects may be explained using the electromagnetic waves emitted by the inlay and by the restoration of biting conditions. Future multidisciplinary research focusing on possible underlying mechanisms regarding the relation between electromagnetic waves and dentistry is necessary.展开更多
Purpose:Myringoplasty aims to improve hearing and prevent otorrhea,making graft uptake rates and hearing crucial considerations.This study analyzed the factors associated with unsuccessful graft uptake and hearing imp...Purpose:Myringoplasty aims to improve hearing and prevent otorrhea,making graft uptake rates and hearing crucial considerations.This study analyzed the factors associated with unsuccessful graft uptake and hearing improvement to guide the selection of optimal surgical approaches for myringoplasty.Methods:We retrospectively reviewed 56 ears with chronic otitis media.All patients were followed up for>6 months after tympanic membrane closure surgery.We compared the underlay method using the transcanal approach with the inlay method using the retroauricular approach for myringoplasty in patients with chronic otitis media.The underlay and inlay methods were used for 23 and 33 ears,respectively.The primary outcomes were graft uptake rate and hearing improvement.Additionally,factors such as the location of tympanic membrane perforation,patient age,and the degree of mastoid development were evaluated.Results:The perforation rate was high when the transcanal underlay method was employed to repair perforations in the anterior inferior quadrant.Both the underlay and inlay methods significantly improved hearing.However,the success rate of the inlay method was lower.Within the cases performed using the inlay method,outcomes tended to be poorer in older age groups.There were no significant differences in surgical success rates related to mastoid development.Conclusion:The inlay method using the retroauricular approach is a favorable option for repairing perforations involving the anterior inferior quadrant.However,older patients presented lower rates of hearing improvement when the inlay method was used.展开更多
In the experimental garden of the Department of Soil Bioengineering and Landscape Construction, University of Applied Life Sciences in Vienna, Austria, coarse root systems of three different brush species were complet...In the experimental garden of the Department of Soil Bioengineering and Landscape Construction, University of Applied Life Sciences in Vienna, Austria, coarse root systems of three different brush species were completely excavated and semiutomatically digitized. The species were Lonicera xylosteum, Ligustrum vulgare and Euonymus europaeus. The 3-D root architectures reveal different growth strategies between species, which are related to ecological characteristics and physical soil properties. The root architecture of Lonicera xylosteum and Ligustrum vulgare, planted in the under layer of the live slope grading, where the soil is very tight and the soil water content and fertility are relatively low, is shallow. However, the root distribution of E. europaeus, planted in the middle layer, where environmental conditions are better, is deeper. Most of the root biomass of the three species is concentrated in the 0-30 cm soil layer. A quarter of the root biomass ofLigustrum vulgare is distributed in the upper layer of the plant inlay. E. europaeus has a relatively even distribution in the 30-0 cm and 60-90 cm soil layer.展开更多
文摘AIM：To provide a side-by-side analysis of the summary of safety and effectiveness data（SSED）submitted to the FDA for the KAMRA and Raindrop corneal inlays for the correction of presbyopia.METHODS：SSED reports submitted to the FDA for KAMRA and Raindrop were compared with respect to loss of corrected distance visual acuity（CDVA）,adverse event rates,induction of astigmatism,retention of contrast sensitivity,stability of manifest refractive spherical equivalent（MRSE）,and achieved monocular uncorrected near visual acuity（UNVA）at 24mo.RESULTS：Totally 442/508 of KAMRA patients and344/373 Raindrop patients remained enrolled in the clinical trials at 24mo.The proportion of KAMRA and Raindrop patients who lost≥2 lines of CDVA at 24mo was 3.4%and1%,respectively.The adverse event rate was comparable between the devices.No significant inductions of astigmatism were noted.Both technologies induced a transient myopic shift in MRSE followed by a hyperopic shift and subsequent stabilization.Totally 87%of KAMRA and 98%of Raindrop patients attained a monocular UNVA of J5（20/40）or better at 24mo,28%of KAMRA and 67%of Raindrop patients attained a monocular UNVA of J1（20/20）or better at 24mo.CONCLUSION：Both devices can be considered safe and effective,however,the results of corneal inlay implantation are mixed,and long-term patient satisfaction will likely depend on subjective expectations about the capabilities of the inlays.Variability in surgical technique and postoperative care within and between the two clinical trials diminishes the comparative power of this article.
基金the financial support from NIH grants(EY016415)to J.L.FunderburghCore grant(P30-EY08098)+1 种基金Other support was received from the Ocular Tissue Engineering and Regenerative Ophthalmology(OTERO)program of the Louis J Fox Center for Vision Restorationthe McGowan Institute for Regenerative Medicine,Research to Prevent Blindness Inc
文摘Corneal inlays and onlays represent a means of providing patients with permanent refractive error correction. As an alternative to conventional spectacles and contact lens, these techniques are less invasive compared with laser-based refractive surgery and are reversible. In this review, we provide a brief overview of the anatomic microstructure of the human cornea, indicating the primary physiological function for each component. Next, the wide range of biomaterials used as corneal inlays and onlays are considered, from synthetic polymers to biological components derived from the extracellular matrix. The limitations and challenges associated with the most common materials are discussed as is the need to improve their properties to achieve long-term, complication-free intraocular implantation. Finally, the prospect of applying tissue engineering strategies is noted for its potential to generate autologous corneal tissue that could be implanted as the optimal inlay or onlay materials.
文摘The art of polychrome lacquer painting with gold tracing and inlay represents the culmination of traditional Chinese lacquer craftsmanship.It integrates four core techniques-lacquer application,polychrome painting,gold tracing,and inlay-embodying the pinnacle of ancient artisan ingenuity.This paper begins by outlining the historical origins,technical characteristics,and cultural significance of this art form.Subsequently,using a Qing Dynasty“Hanging Screen Inlaid with Boxwood and Coral Depicting the Scene of Sudhana Paying Homage to Guanyin,with Polychrome Lacquer Painting and Gold Tracing”as a case study,it offers an in-depth analysis of its craftsmanship,visual elements,thematic narrative,and cultural connotations.The study aims to unveil its artistic value and contemporary relevance as a form of“living cultural heritage.”
文摘The Chinese incense burner,a cornerstone of material culture,embodies distinguished craftsmanship and reflects sociocultural evolution across ritual,religious,and domestic life.Through analysis of a Qing-dynasty copper Ding-style censer with gold and silver inlay,this paper examines its antique form,masterly technique,and decorative motifs.It demonstrates how such objects synthesize the cultural ethos of the Kang-Qian era by uniting Ming-Song literati classicism with consummate imperial artistry.This case study thus provides a focused lens on the critical interplay between elite taste and technical execution in the history of Chinese craftsmanship.
文摘Objective: A new indirect composite restorative system with water combingpressure, light, and heat was introduced for the fabrication of inlays and onlays. Methods: Fifteendefected teeth were selected for composite resin inlay and onlay fabrication with Tescera ATL unitequipment. The clinical trial was carried out for 3 months. Results: After 3 months test, 7parameters were checked, 15 Tescera inlays and onlays were demonstrated that exceptional esthetics,all 7 parameters were good and the patients were very satisfied. Conclusion: inlays , which weremade with Tescera ATL restorative system, are esthetics; physical properties of materials areimproved highly, and have a long-lasting durability. This restorative system is worthy to be usedand further studied in dental practice.
基金supported by the Ministry of Commerce, Industry and Energy (MOCIE) of Korea (10031777)
文摘A reliability of flip-chip bonded die as a function of anisotropic conductive paste (ACP) hybrid materials, bonding conditions, and antenna pattern materials was investigated during the assembly of radio frequency identification(RFID) inlay. The optimization condition for flip-chip bonding was determined from the behavior of bonding strength. Under the optimized condition, the shear strength for the antenna printed with paste-type Ag ink was larger than that for Cu antenna. Furthermore, an identification distance was varied from the antenna materials. Comparing with the Ag antenna pattern, the as-bonded die on Cu antenna showed a larger distance of identification. However, the long-term reliability of inlay using the Cu antenna was decreased significantly as a function of aging time at room temperature because of the bended shape of Cu antenna formed during the flip-chip bonding process.
文摘The purpose of this study was to demonstrate the improvement of hip joint dysregulation, including pain (coxalgia), tension, and restriction of joint mobility, using a dental gold alloy inlay. The subject was a 63-year-old man who was suffering from the abovementioned symptoms for several months. On placement of the gold alloy inlay on his chest, the joint flexibility was observed to increase, and the severity of the abovementioned symptoms decreased. When the inlay was placed in his tooth, the flexibility of the joint further increased, and all other symptoms disappeared. No side effects were observed, and the prognosis was good. We believe that these effects may be explained using the electromagnetic waves emitted by the inlay and by the restoration of biting conditions. Future multidisciplinary research focusing on possible underlying mechanisms regarding the relation between electromagnetic waves and dentistry is necessary.
文摘Purpose:Myringoplasty aims to improve hearing and prevent otorrhea,making graft uptake rates and hearing crucial considerations.This study analyzed the factors associated with unsuccessful graft uptake and hearing improvement to guide the selection of optimal surgical approaches for myringoplasty.Methods:We retrospectively reviewed 56 ears with chronic otitis media.All patients were followed up for>6 months after tympanic membrane closure surgery.We compared the underlay method using the transcanal approach with the inlay method using the retroauricular approach for myringoplasty in patients with chronic otitis media.The underlay and inlay methods were used for 23 and 33 ears,respectively.The primary outcomes were graft uptake rate and hearing improvement.Additionally,factors such as the location of tympanic membrane perforation,patient age,and the degree of mastoid development were evaluated.Results:The perforation rate was high when the transcanal underlay method was employed to repair perforations in the anterior inferior quadrant.Both the underlay and inlay methods significantly improved hearing.However,the success rate of the inlay method was lower.Within the cases performed using the inlay method,outcomes tended to be poorer in older age groups.There were no significant differences in surgical success rates related to mastoid development.Conclusion:The inlay method using the retroauricular approach is a favorable option for repairing perforations involving the anterior inferior quadrant.However,older patients presented lower rates of hearing improvement when the inlay method was used.
文摘In the experimental garden of the Department of Soil Bioengineering and Landscape Construction, University of Applied Life Sciences in Vienna, Austria, coarse root systems of three different brush species were completely excavated and semiutomatically digitized. The species were Lonicera xylosteum, Ligustrum vulgare and Euonymus europaeus. The 3-D root architectures reveal different growth strategies between species, which are related to ecological characteristics and physical soil properties. The root architecture of Lonicera xylosteum and Ligustrum vulgare, planted in the under layer of the live slope grading, where the soil is very tight and the soil water content and fertility are relatively low, is shallow. However, the root distribution of E. europaeus, planted in the middle layer, where environmental conditions are better, is deeper. Most of the root biomass of the three species is concentrated in the 0-30 cm soil layer. A quarter of the root biomass ofLigustrum vulgare is distributed in the upper layer of the plant inlay. E. europaeus has a relatively even distribution in the 30-0 cm and 60-90 cm soil layer.
