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Prompt Injection Attacks on Large Language Models:A Survey of Attack Methods,Root Causes,and Defense Strategies
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作者 Tongcheng Geng Zhiyuan Xu +1 位作者 Yubin Qu W.Eric Wong 《Computers, Materials & Continua》 2026年第4期134-185,共52页
Large language models(LLMs)have revolutionized AI applications across diverse domains.However,their widespread deployment has introduced critical security vulnerabilities,particularly prompt injection attacks that man... Large language models(LLMs)have revolutionized AI applications across diverse domains.However,their widespread deployment has introduced critical security vulnerabilities,particularly prompt injection attacks that manipulate model behavior through malicious instructions.Following Kitchenham’s guidelines,this systematic review synthesizes 128 peer-reviewed studies from 2022 to 2025 to provide a unified understanding of this rapidly evolving threat landscape.Our findings reveal a swift progression from simple direct injections to sophisticated multimodal attacks,achieving over 90%success rates against unprotected systems.In response,defense mechanisms show varying effectiveness:input preprocessing achieves 60%–80%detection rates and advanced architectural defenses demonstrate up to 95%protection against known patterns,though significant gaps persist against novel attack vectors.We identified 37 distinct defense approaches across three categories,but standardized evaluation frameworks remain limited.Our analysis attributes these vulnerabilities to fundamental LLM architectural limitations,such as the inability to distinguish instructions from data and attention mechanism vulnerabilities.This highlights critical research directions such as formal verification methods,standardized evaluation protocols,and architectural innovations for inherently secure LLM designs. 展开更多
关键词 Prompt injection attacks large language models defense mechanisms security evaluation
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Penile shaft reconstruction after cream self-injection:a case report
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作者 Léa Bollen Stéphane Rysselinck +1 位作者 Jean-Philippe Salmin Gilles Dosin 《The Canadian Journal of Urology》 2026年第1期221-225,共5页
Background:Penile augmentation through injectable substances is becoming increasingly common.A growing number of aesthetic clinics are developing penile enlargement procedures using various injectable materials.Althou... Background:Penile augmentation through injectable substances is becoming increasingly common.A growing number of aesthetic clinics are developing penile enlargement procedures using various injectable materials.Although these procedures are now performed in more controlled and medically supervised environments,their long-term outcomes remain poorly understood.The promotion of such medical treatments contributes to an increasing interest among adult males in self-injection as a method to alleviate psychological distress associated with penile size concerns.At the same time,access to injectable substances through unofficial or unregulated sources has become increasingly easy.Tor our knowledge,we report the first documented case of self-injection with Garamycin®(gentamicin)cream,contributing to the literature on the often multidisciplinary management of penile enlargement injections,a field still lacking well-established guidelines.Case Description:This case report describes a young patient who self-injected Garamycin®into the penis for the purpose of enlargement.He presented to our urology department with worsening symptoms,including severe and poorly tolerated pain.His primary request was prompt relief of pain while preserving,as much as possible,the aesthetic appearance and functional integrity of his penis.This case required a multi-stage surgical approach to salvage the penis and preserve both its structural integrity and functional outcome.Conclusions:To our knowledge,this case report documents the first reported instance of Garamycin®injection performed for the purpose of penile enlargement.It provides insight into the clinical course of such penile cream injections,demonstrates that a two-stage scrotal flap can achieve both functional and aesthetic outcomes,and highlights the importance of comprehensive management particularly addressing the traumatic impact of penile deformity secondary to inflammation and/or infection,as well as the body dysmorphic concerns often associated with these cases. 展开更多
关键词 penile augmentation foreign body injection penile reconstruction scrotal flap complications case report
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The Impact of Double-puncture Tympanic Membrane Puncture and Tympanic Cavity Drug Injection on the Complication Rate of Acute Secretory Otitis Media
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作者 Wei Zheng 《Proceedings of Anticancer Research》 2026年第1期54-60,共7页
Objective:To explore the therapeutic effect of double-puncture tympanic membrane puncture and tympanic cavity drug injection in patients with acute secretory otitis media.Methods:A total of 84 patients with acute secr... Objective:To explore the therapeutic effect of double-puncture tympanic membrane puncture and tympanic cavity drug injection in patients with acute secretory otitis media.Methods:A total of 84 patients with acute secretory otitis media admitted to our hospital from June 2024 to June 2025 were selected and randomly divided into two groups by drawing lots.The control group(42 cases)was treated with the traditional single-puncture tympanic membrane puncture and tympanic cavity drug injection method,while the observation group(42 cases)was treated with the double-puncture tympanic membrane puncture and tympanic cavity drug injection method.The therapeutic effects of the two groups were compared.Results:The overall treatment response rate,overall complication rate,time to symptom relief,and improvement in hearing threshold in the observation group were all superior to those in the control group,with statistically significant differences(P<0.05).Conclusion:For acute secretory otitis media,the treatment method of double-puncture tympanic membrane puncture and tympanic cavity drug injection demonstrates definite efficacy,significantly reducing the incidence of complications,accelerating symptom relief,and improving hearing function,making it worthy of promotion. 展开更多
关键词 Acute secretory otitis media Double puncture Tympanic membrane puncture and tympanic cavity drug injection COMPLICATIONS
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Clinical observation on prognosis of mixed hemorrhoids treated with polidocanol injection combined with automatic elastic thread ligation operation 被引量:3
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作者 Yan-Mei Huang Dong Ouyang 《World Journal of Gastrointestinal Surgery》 2025年第1期209-216,共8页
BACKGROUND A total of 100 patients diagnosed with mixed hemorrhoids from October 2022 to September 2023 in our hospital were randomly divided into groups by dice rolling and compared with the efficacy of different tre... BACKGROUND A total of 100 patients diagnosed with mixed hemorrhoids from October 2022 to September 2023 in our hospital were randomly divided into groups by dice rolling and compared with the efficacy of different treatment options.AIM To analyze the clinical effect and prognosis of mixed hemorrhoids treated with polidocanol injection combined with automatic elastic thread ligation operation(RPH).METHODS A total of 100 patients with mixed hemorrhoids who visited our hospital from October 2022 to September 2023 were selected and randomly divided into the control group(n=50)and the treatment group(n=50)by rolling the dice.The procedure for prolapse and hemorrhoids(PPH)was adopted in the control group,while polidocanol foam injection+RPH was adopted in the treatment group.The therapeutic effects,operation time,wound healing time,hospital stay,pain situation(24 hours post-operative pain score,first defecation pain score),quality of life(QOL),incidence of complications(post-operative hemorrhage,edema,infection),incidence of anal stenosis 3 months post-operatively and recurrence rate 1 year post-operatively of the two groups were compared.RESULTS Compared with the control group,the total effective rate of treatment group was higher,and the difference was significant(P<0.05).The operation time/wound healing time/hospital stay in the treatment group were shorter than those in the control group(P<0.05).The pain scores at 24 hours after operation/first defecation pain score of the treatment group was significantly lower than those in the control group(P<0.05).After surgery,the QOL scores of the two groups decreased,with the treatment group having higher scores than that of the control group(P<0.05).Compared with the control group,the incidence of postoperative complications in the treatment group was lower,and the difference was significant(P<0.05);However,there was no significant difference in the incidence of postoperative bleeding between the two groups(P>0.05);There was no significant difference in the incidence of anal stenosis 3 months after operation and the recurrence rate 1 year after operation between the two groups(P>0.05).CONCLUSION For patients with mixed hemorrhoids,the therapeutic effect achieved by using polidocanol injection combined with RPH was better.The wounds of the patients healed faster,the postoperative pain was milder,QOL improved,and the incidence of complications was lower,and the short-term and long-term prognosis was good. 展开更多
关键词 Mixed hemorrhoids Polidocanol injection Automatic elastic thread ligation operation Postoperative hemorrhage The degree of pain Recurrent rate
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Numerical simulation of the effect of hydrogen injection and oxygen enrichment interaction on PCI in a blast furnace 被引量:1
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作者 Huan Liu Li Huang +3 位作者 Zhenyang Wang Alberto N.Conejo Jianliang Zhang Dawei Lan 《International Journal of Minerals,Metallurgy and Materials》 2025年第7期1551-1565,共15页
Hydrogen displays the potential to partially replace pulverized coal injection(PCI)in the blast furnace,and it can reduce CO_(2)emissions.In this paper,a three-dimensional mathematical model of hydrogen and pulverized... Hydrogen displays the potential to partially replace pulverized coal injection(PCI)in the blast furnace,and it can reduce CO_(2)emissions.In this paper,a three-dimensional mathematical model of hydrogen and pulverized coal co-injection in blast furnace tuyere was established through numerical simulation,and the effect of hydrogen injection and oxygen enrichment interaction on pulverized coal combustion and raceway smelting was investigated.The simulation results indicate that when the coal injection rate decreased from 36 to 30t/h and the hydrogen injection increased from 0 to 3600 m^(3)/h,the CO_(2)emissions decreased from 1860 to 1551 kg/t,which represents a16.6%reduction,and the pulverized coal burnout decreased from 70.1%to 63.7%.The heat released from hydrogen combustion can not only promote the volatilization of pulverized coal but also affect the combustion reaction between volatilization and oxygen,which resulted in a decrease in the temperature at the end of the raceway.Co-injection of hydrogen with PCI increased the wall temperature near the upper half part of the raceway and at the outlet of the tuyere,which required a high cooling efficiency to extend the service life of the blast furnace.The increase in oxygen level compensated for the decreased average temperature in the raceway due to hydrogen injection.The increase in the oxygen content by 3%while maintaining constant hydrogen and PCI injection rates increased the burnout and average raceway temperature by 4.2%and 43 K,respectively.The mole fraction of CO and H_(2) production increased by 0.04 and 0.02,respectively.Burnout can be improved through optimization of the particle size distribution of pulverized coal. 展开更多
关键词 blast furnace HYDROGEN pulverized coal injection BURNOUT numerical simulation
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Synergistic exploitation of gas hydrates through surface seawater injection coupled with depressurization:Application and optimization in the South China Sea 被引量:1
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作者 Yuxuan Li Zhaobin Zhang +6 位作者 Rick Chalaturnyk Shouding Li Jianming He Hang Bian Xiao Li Cheng Lu Xuwen Qin 《International Journal of Mining Science and Technology》 2025年第11期1921-1937,共17页
This study proposes and systematically evaluates an optimized integration of warm surface seawater injection with depressurization for the long-term exploitation of marine natural gas hydrates.By employing comprehensi... This study proposes and systematically evaluates an optimized integration of warm surface seawater injection with depressurization for the long-term exploitation of marine natural gas hydrates.By employing comprehensive multiphysics simulations guided by field data from hydrate production tests in the South China Sea,we pinpoint key operational parameters—such as injection rates,depths,and timings—that notably enhance production efficiency.The results indicate that a 3-phase hydrate reservoir transitions from a free-gas-dominated production stage to a hydrate-decomposition-dominated stage.Moderate warm seawater injection supplies additional heat during the hydrate decomposition phase,thereby enhancing stable production;however,excessively high injection rates can impede the depressurization process.Only injection at an appropriate depth simultaneously balances thermal supplementation and the pressure gradient,leading to higher overall productivity.A“depressurization-driven sensible-heat supply window”is introduced,highlighting that timely seawater injection following initial depressurization prolongs reservoir dissociation dynamics.In this study area,commencing seawater injection at 170 d of depressurization proved optimal.This optimized integration leverages clean and renewable thermal energy,providing essential insights into thermal supplementation strategies with significant implications for sustainable,economically feasible,and efficient commercial-scale hydrate production. 展开更多
关键词 Natural gas hydrates Surface seawater injection Multiphysics simulations Thermal supplementation Sensible-heat supply window
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Simulation and Experiment of Windage Power Loss of A Shrouded Spiral Bevel Gears under Oil Injection Lubrication 被引量:1
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作者 Bo Li Kai Rong +4 位作者 Xuyang Zhang Sanmin Wang U-Xuan Tan Xuanyuan Su Laifa Tao 《Chinese Journal of Mechanical Engineering》 2025年第2期407-426,共20页
During high-speed rotation,the surface of aeronautic spiral bevel gears will generate significant pressure and viscous forces,which will cause a certain amount of windage power loss and reduce the efficiency of the tr... During high-speed rotation,the surface of aeronautic spiral bevel gears will generate significant pressure and viscous forces,which will cause a certain amount of windage power loss and reduce the efficiency of the transmission system.Based on the computational fluid dynamics,this paper analyzes the windage power loss of a single spiral bevel gear and a spiral bevel gear pair under oil injection lubrication.In addition,the shroud is used to suppress gear windage loss,and the clearance size and opening angle of the designed shroud are optimized.Finally,by comparing and analyzing the experimental results,the following conclusions were obtained:(1)For a single gear,the speed is the most important factor affecting windage loss,followed by the hand of spiral,and rotation direction;(2)For gear pairs,under oil injection lubrication,the input speed has the greatest impact on windage power loss,followed by the influence of oil injection port speed,temperature and oil injection port pressure;(3)Installing a shroud is an effective method to reduce windage power loss;(4)In the pure air phase,the smaller the clearance between the shroud and the gear surface,and the smaller the radial direction between the shroud and the shaft,the better the effect of reducing windage;(5)In the two-phase flow of oil and gas,it is necessary to design oil drainage holes on the shroud to ensure the smooth discharge of lubricating oil and improve the drag reduction effect. 展开更多
关键词 Computational fluid dynamics(CFD) Windage power loss Spiral bevel gear SHROUD Oil injection lubrication
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Application of Meridian flow injection acupoint application combined with transcutaneous electrical acupoint stimulation in patients undergoing gastroenteroscopy 被引量:1
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作者 Xian Hong Xiao-Yan Wu Qing-Li Xu 《World Journal of Gastroenterology》 2025年第36期113-121,共9页
BACKGROUND Although gastroscopy is a commonly used diagnostic and therapeutic technique,postoperative gastrointestinal dysfunction is prone to occur.Traditional Chinese medicine theory suggests that postoperative gast... BACKGROUND Although gastroscopy is a commonly used diagnostic and therapeutic technique,postoperative gastrointestinal dysfunction is prone to occur.Traditional Chinese medicine theory suggests that postoperative gastrointestinal disorders are related to spleen and stomach weakness.This study hypothesizes that the combination of acupoint application at the Ziwu Liuzhu acupoint and percutaneous acupoint electrical stimulation can promote postoperative gastrointestinal function recovery and alleviate stress reactions.AIM To investigate the effects of acupoint application of Ziwu Liuzhu combined with percutaneous acupoint electrical stimulation on postoperative gastrointestinal function recovery and stress response in patients undergoing gastrointestinal endoscopy surgery.METHODS A total of 120 patients who underwent gastroscopy surgery were selected and treated between October 2024 and January 2025.This study used a stratified block randomization method,and then allocated groups using computer-generated random number sequences(SAS 9.4 software).The groups were divided into two groups:A control group of 60 patients who received routine postoperative intervention measures,and an observation group of 60 patients who received acupuncture point application combined with transcutaneous acupoint electrical CONCLUSION The combination of percutaneous acupoint electrical stimulation in gastroscopy patients has been demonstrated to be both highly safe and effective.The benefits of this approach include the promotion of postoperative gastrointestinal function,the reduction of stress response,the attainment of optimal results,and the enhancement of patient satisfaction. 展开更多
关键词 Meridian flow injection acupoint application Acupoint application Transcutaneous electrical acupoint stimulation GASTROSCOPY Gastrointestinal function Stress response
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Systematic experimental investigation on pressure build-up characteristics of water-jet injection into a molten LBE pool 被引量:1
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作者 Hao-Ran Huang Zi-Jian Deng +1 位作者 Song-Bai Cheng Jia-Yue Chen 《Nuclear Science and Techniques》 2025年第1期161-174,共14页
In the scenario of a steam generator tube rupture accident in a lead-cooled fast reactor,secondary circuit subcooled water under high pressure is injected into an ordinary-pressure primary vessel,where a molten lead-b... In the scenario of a steam generator tube rupture accident in a lead-cooled fast reactor,secondary circuit subcooled water under high pressure is injected into an ordinary-pressure primary vessel,where a molten lead-based alloy(typically pure lead or lead-bismuth eutectic(LBE))is used as the coolant.To clarify the pressure build-up characteristics under water-jet injection,this study conducted several experiments by injecting pressurized water into a molten LBE pool at Sun Yat-sen University.To obtain a further understanding,several new experimental parameters were adopted,including the melt temperature,water subcooling,injection pressure,injection duration,and nozzle diameter.Through detailed analyses,it was found that the pressure and temperature during the water-melt interaction exhibited a consistent variation trend with our previous water-droplet injection mode LBE experiment.Similarly,the existence of a steam explosion was confirmed,which typically results in a much stronger pressure build-up.For the non-explosion cases,increasing the injection pressure,melt-pool temperature,nozzle diameter,and water subcooling promoted pressure build-up in the melt pool.However,a limited enhancement effect was observed when increasing the injection duration,which may be owing to the continually rising pressure in the interaction vessel or the isolation effect of the generated steam cavity.Regardless of whether a steam explosion occurred,the calculated mechanical and kinetic energy conversion efficiencies of the melt were relatively small(not exceeding 4.1%and 0.7%,respectively).Moreover,the range of the conversion efficiency was similar to that of previous water-droplet experiments,although the upper limit of the jet mode was slightly lower. 展开更多
关键词 Lead-cooled fast reactor Steam generator tube rupture accident Pressure build-up characteristics Experimental study Pressure water-jet injection
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Refractory lipoatrophy treated with autologous whole blood injection:A case report
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作者 Wonnam Kim Jun Su Park En Hyung Kim 《World Journal of Clinical Cases》 SCIE 2025年第2期33-38,共6页
BACKGROUND Intramuscular corticosteroid injection may cause adverse effects such as dermal and/or subcutaneous atrophy,alopecia,hypopigmentation,and hyperpigmentation.Although cutaneous atrophy can spontaneously resol... BACKGROUND Intramuscular corticosteroid injection may cause adverse effects such as dermal and/or subcutaneous atrophy,alopecia,hypopigmentation,and hyperpigmentation.Although cutaneous atrophy can spontaneously resolve,several treatment options have been suggested for this condition.CASE SUMMARY In this paper,we report a case of corticosteroid injection induced lipoatrophy treated with autologous whole blood(AWB)injection,as the condition had been unresponsive to fractional laser therapy.A 29-year-old female patient visited the dermatology clinic complaining of skin depression on her right buttock area,which had appeared six months earlier.There had been only subtle improvement at the margins after fractional CO_(2) laser treatment;therefore,after obtaining informed consent from the patient,AWB treatment was initiated.One month after the first AWB injection,the size and depth of the lesion had noticeably improved,and a slight improvement was also observed in discoloration.CONCLUSION Close observation is the initial treatment of choice for steroid induced skin atrophy;however,for patients in need of immediate cosmetic improvement,AWB injection may be a safe and cost-effective alternative. 展开更多
关键词 ATROPHY CORTICOSTEROID Subcutaneous fat Autologous whole blood injection Laser therapy Case report
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Retrospective Review Investigating the Efficacy of the Gray/Campbell Migraine Injection Protocol for OnabotulinumtoxinA (A Modified PREEMPT Injection Paradigm for Chronic Migraine Treatment)
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作者 Colin Campbell Terence K. Gray +1 位作者 Ajay Challapalli Grace Gray 《Pain Studies and Treatment》 2025年第1期14-26,共13页
Chronic migraine is a potentially debilitating condition that can be detrimental to someone’s quality of life. Clinical data has proven OnabotulinumtoxinA (BoNT-A) to be an effective prophylactic treatment for chroni... Chronic migraine is a potentially debilitating condition that can be detrimental to someone’s quality of life. Clinical data has proven OnabotulinumtoxinA (BoNT-A) to be an effective prophylactic treatment for chronic headache types, and it is now regularly employed by headache treatment centers. The PREEMPT injection protocol has become the standard treatment regimen surrounding Botox injections for chronic migraine treatment since it was granted approval by the FDA in 2010. This retrospective chart review of patients treated for chronic migraine at Maine Comprehensive Pain Management in Scarborough, Maine, presents an alteration to the standard PREEMPT injection paradigm that reinforces the efficacy of Botox for chronic migraine treatment. We will discuss our Modified PREEMPT injection paradigm, which yields a positive clinical response rate of 95% of patients achieving at least 50% improvement in their migraine headaches. This appears to be the highest established response rate in the literature to date. 展开更多
关键词 ONABOTULINUMTOXINA Botox injection
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Effects of Split Injection on Combustion,Emissions,and Intermediate Species of Natural Gas High-Pressure Direct Injection Engine
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作者 Lijiang Wei Xiuwei Lu +1 位作者 Wenqing Huang Qimin Song 《哈尔滨工程大学学报(英文版)》 2025年第1期210-223,共14页
Using natural gas(NG)as the primary fuel helps alleviate the fossil fuel crisis while reducing engine soot and nitrogen oxide(NO_(X))emissions.In this paper,the influences of a novel split injection concept on an NG h... Using natural gas(NG)as the primary fuel helps alleviate the fossil fuel crisis while reducing engine soot and nitrogen oxide(NO_(X))emissions.In this paper,the influences of a novel split injection concept on an NG high pressure direct injection(HPDI)engine are examined.Four typical split injection strategies,namely split pre-injection of pilot diesel(PD)and NG,split post-injection of PD and NG,split pre-injection of NG,and split post-injection of PD,were developed to investigate the influences on combustion and emissions.Results revealed that split pre injection of NG enhanced the atomization of PD,whereas the split post-injection of NG lowered the temperature in the core region of the PD spray,resulting in the deterioration of combustion.The effect of the split injection strategy on indicated thermal efficiency exceeded 7.5%.Split pre-injection was favorable to enhancing thermal efficiency,whereas split post-injection was not.Ignition delay,combustion duration,and premixed combustion time proportion were affected by injection strategies by 3.8%,50%,and 19.7%,respectively.Split pre-injection increased CH_(4) emission in the exhaust.Split post-injection,especially split post-injection of PD and NG,reduced the unburned CH_(4) emission by approximately 30%.When the split post-injection ratio was less than 30%,the trade-off between NO_(X) and soot was interrupted.The distribution range of hydroxyl radicals was expanded by pre-injection,and NO_(X) was generated in the region where the NG jet hit the wall.This paper provides valuable insights into the optimization of HPDI injection parameters. 展开更多
关键词 High pressure direct injection Natural gas Split injection strategy injection ratio COMBUSTION
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Effectively simplified Adriamycin-induced chronic kidney disease mouse model:Retro-orbital vein injection versus tail-vein injection
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作者 Masaki Watanabe Hayato R.Takimoto +2 位作者 Kazuki Hashimoto Yuki Ishii Nobuya Sasaki 《Animal Models and Experimental Medicine》 2025年第3期568-572,共5页
This study aimed to investigate the impact of administration routes in establishing the Adriamycin(ADR)-induced chronic kidney disease(CKD)model.Using BALB/c mice,we compared the effects of conventional tail-vein inje... This study aimed to investigate the impact of administration routes in establishing the Adriamycin(ADR)-induced chronic kidney disease(CKD)model.Using BALB/c mice,we compared the effects of conventional tail-vein injection(TV10,10 mg/kg)to those of retro-orbital sinus(orbital vein)injection(OV10,10 mg/kg;OV8,8 mg/kg).The re-sults indicated that the OV10 group exhibited CKD pathology similar to the TV10 group,with both groups demonstrating significantly higher urinary albumin/creatinine ratio(p<0.05),tubular injury(p<0.05),and degree of renal fibrosis(p<0.05)than the OV8 group.No significant differences were observed between the OV10 and TV10 groups in urinary albumin/creatinine ratio,tubular injury,and degree of renal fibrosis.These findings demonstrated that retro-orbital administration of 10 mg/kg ADR in-duces comparable effects to conventional tail-vein administration.This technique's technical simplicity may improve experimental efficiency,reproducibility,and animal welfare in CKD research.In conclusion,this study validates the utility of retro-orbital injection in CKD model establishment,demonstrating its potential to standardize and improve the reliability of future CKD research protocols. 展开更多
关键词 Adriamycin nephropathy BALB/c CKD orbital vein injection tail-vein injection
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Author Correction:Preoperative application of combination of portal venous injection of donor spleen cells and intraperitoneal injection of rapamycin prolongs the survival of cardiac allografts in mice
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《Asian Pacific Journal of Tropical Medicine》 2025年第6期288-288,共1页
Wen-lin Gong1,Chuang Sha2,Gang Du1,Zhong-gui Shan3,Zhong-quan Qi3,Su-fang Zhou1,Nuo Yang1,4,Yong-xiang Zhao1,4.First published:21 June 2017;10(5):454-460.DOI:10.1016/j.apjtm.2017.05.004 The authors would like to corre... Wen-lin Gong1,Chuang Sha2,Gang Du1,Zhong-gui Shan3,Zhong-quan Qi3,Su-fang Zhou1,Nuo Yang1,4,Yong-xiang Zhao1,4.First published:21 June 2017;10(5):454-460.DOI:10.1016/j.apjtm.2017.05.004 The authors would like to correct an error in Figure 3 in which the flow cytometric scattergram of CD4/CD44 for the control group was erroneously used for the scattergram of CD8/CD44 for the PVIDSC group.The correct scattergram of CD8/CD44 for the PVIDSC group is provided below.The error does not affect the conclusion of the study.The authors apologize for the error and the inconvenience it might have caused to readers. 展开更多
关键词 intraperitoneal injection cardiac allograft survival CD CD flow cytometric scattergram portal venous injection RAPAMYCIN
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The occurrence of propofol injection pain in the emergency department:an exploratory analysis
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作者 Mischa Veen M.Christien van der Linden 《World Journal of Emergency Medicine》 2025年第2期161-163,共3页
Propofol(2,6-di-isopropylphenol) is a short-acting,intravenous sedative drug.^([1,2]) The pharmacologic mechanism of propofol is related to its agonistic effects on the gamma-amino butyric acid receptor.^([1-3]) Propo... Propofol(2,6-di-isopropylphenol) is a short-acting,intravenous sedative drug.^([1,2]) The pharmacologic mechanism of propofol is related to its agonistic effects on the gamma-amino butyric acid receptor.^([1-3]) Propofol injection pain(PIP) is well-known in the operating room and is commonly countered by the prophylactic administration of lidocaine.In anesthesia,PIP is encountered in 28%–90% of patients.^([4,5]) However,PIPprophylaxis does not seem to be efficacious in every population.^([6,7]) Whether procedural sedation and analgesia(PSA) in the emergency department(ED) warrants lidocaine administration is unclear. 展开更多
关键词 injection ANESTHESIA PAIN
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Abdominal wall hematoma related to subcutaneous low-molecular-weight heparin injection following coronary intervention therapy:case presentation
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作者 Xiao-Hua LIU Yi-Zhou XU 《Journal of Geriatric Cardiology》 2025年第1期214-218,共5页
Subcutaneous administration of low-molecularweight heparin(LMWH)has been widely accepted as an effective anticoagulation therapy and is frequently used for patients to prevent thromboembolic events.While the usually s... Subcutaneous administration of low-molecularweight heparin(LMWH)has been widely accepted as an effective anticoagulation therapy and is frequently used for patients to prevent thromboembolic events.While the usually seen bruising around the injection site during subcutaneous LMWH treatment,the abdominal wall(AW)hematoma(AWH)was scarcely observed and reported.A previous study demonstrated the usual etiological risk of AWH involved anticoagulation therapy,chronic kidney disease,and trauma.^([1])Most of these cases had a favorable prognosis after conservative treatment. 展开更多
关键词 injection HEPARIN HEMATOMA
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Improving accuracy for intra-articular injections for capsulitis of the shoulder by changing the injection technique
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作者 Jan M A Mens Ronald T M Van Kalmthout 《World Journal of Orthopedics》 2025年第11期68-74,共7页
BACKGROUND The accuracy of blind intra-articular injections in the shoulder is rather low.Inaccurate injections tend to lead to poorer treatment outcomes.The“Delaware posterior bone touch technique”has shown higher ... BACKGROUND The accuracy of blind intra-articular injections in the shoulder is rather low.Inaccurate injections tend to lead to poorer treatment outcomes.The“Delaware posterior bone touch technique”has shown higher accuracy in young,slender,healthy volunteers than the classical“Cyriax technique”.AIM To investigate whether the Delaware technique would also be more accurate in older patients with capsulitis.METHODS We analyzed the files of 100 consecutive patients with capsulitis who were treated with an intra-articular injection containing a mixture of triamcinolone,lidocaine,and air.After the injection,the shoulder was moved to determine whether a squishing sound could be produced.The squishing sound was interpreted as an accurate injection.The scores with the new Delaware technique were compared against those with the Cyriax technique in a previous study.RESULTS Squishing was heard after 87%of the injections.This was 13%(10%points)more than the 77%in the previous study(P=0.004).CONCLUSION The Delaware technique was significantly more accurate than the Cyriax technique also in middle aged patients with capsulitis.We hypothesize that the difference is caused by a lower risk that a part of the opening of the needle is still outside the capsule. 展开更多
关键词 Capsulitis SHOULDER Intra-articular injections GLUCOCORTICOID ACCURACY
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Establishing a fault sealing discrimination method to determine the optimal injection sites and injection rate for CO_(2) storage in complex fault-block geological bodies
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作者 Zi-Yang Song Lei-Lei Yang +4 位作者 Yi Liu Fu-Jie Jiang Xiao-Feng Li Zhen-Guo Qi Zhen-Yuan Yin 《Petroleum Science》 2025年第7期2643-2659,共17页
The long-term stability of CO_(2) storage represents a pivotal challenge in geological CO_(2) storage(CGS),particularly within deep saline aquifers characterized by complex fault-block systems.While the injection site... The long-term stability of CO_(2) storage represents a pivotal challenge in geological CO_(2) storage(CGS),particularly within deep saline aquifers characterized by complex fault-block systems.While the injection sites and rate under different fault structures will directly affect the CO_(2) storage effect and the risk of leakage.This study investigates the Gaoyou Sag in the Subei Basin,a representative fault-block reservoir,through an integrated numerical-experimental approach.A three-dimensional simulation model incorporating multiphase flow dynamics was developed to characterize subsurface CO_(2) transport and dissolution processes.A novel fault seal capacity evaluation framework was proposed,integrating three critical geological indices(fault throw/reservoir thickness/caprock thicknesses)with the coupling of formation physical properties,temperature,and pressure for the rational selection of injection sites and rates.The results show that Optimal storage performance is observed when the fault throw is lower than the reservoir and caprock thicknesses.Furthermore,higher temperature and pressure promote the dissolution and diffusion of CO_(2),while compared to the structural form of faults,the physical properties of faults have a more significant effect on CO_(2) leakage.The larger reservoir space and the presence of an interlayer reduce the risk of CO_(2) leakage,and augmenting storage potential.Decreasing the injection rate increases the proportion of dissolved CO_(2),thereby enhancing the safety of CO_(2) storage. 展开更多
关键词 CCUS CO_(2)geological storage Fault-block geological bodies injection sites injection rate CO_(2)dissolution
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Influence of injection positions on combustion performance in kerosene-fueled multi-cavity Scramjet combustor
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作者 Fangbin LIU Rongchun ZHANG +1 位作者 Riheng ZHENG Qiang SUN 《Chinese Journal of Aeronautics》 2025年第5期92-108,共17页
The kerosene-fueled Scramjet with multi-cavity combustor has the potential to serve aspropulsion system for hypersonic flight.However,the impact of injection positions on combustionperformance and mechanism at high Ma... The kerosene-fueled Scramjet with multi-cavity combustor has the potential to serve aspropulsion system for hypersonic flight.However,the impact of injection positions on combustionperformance and mechanism at high Mach numbers remains uncertain.Therefore,a comparativestudy was conducted using numerical methods to explore multi-cavity Scramjet combustor perfor-mance at a flight Mach number 7.0 with different injection positions.The combustor is equippedwith 6 cavities arranged in three groups along the flow direction,each consisting of two cavities per-pendicular to the flow.It is shown that the injection location significantly influences combustionperformance:Front-injection yields higher combustion efficiency than post-injection,but post-injection is advantageous for the intake start.Additionally,regardless of injection positions,themainstream flow state near the cavities behind the injection can be categorized as supersonic flow,supersonic-subsonic coexistence flow,and subsonic flow.The optimal length from the downstreamto the trailing edge of the cavities behind the injection for achieving maximum combustion effi-ciency is determined.Further extension beyond this optimal length does not significantly increasethe combustion efficiency.In addition,the optimal length varies with different injection positions-specifically,it is about 60%longer with post-injection conditions than with front-injection con-ditions in this investigation.Moreover,significant secondary combustion within the cavities leadingto improved efficiency only occurs when mainstream flow state is either supersonic flow orsupersonic-subsonic coexistence flow.Also,with a well-optimized design,the kerosene-fueledmulti-cavity Scramjet can achieve enhanced combustion efficiency,which shows relatively smallvariation across a wide range of equivalence ratios.This might be caused by the effects of interac-tion among these multiple cavities.Therefore,these research findings can provide valuable insightsfor designing and optimizing the kerosene-fueled multi-cavity combustor in Scramjet at high Machnumbers. 展开更多
关键词 SCRAMJET injection Combustion performance Optimization MULTI-CAVITY
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