Silver nanoparticles(Ag NPs)have attracted attention in the field of biomaterials due to their excellent antibacterial property.However,the reducing and stabilizing agents used for the chemical reduction of Ag NPs are...Silver nanoparticles(Ag NPs)have attracted attention in the field of biomaterials due to their excellent antibacterial property.However,the reducing and stabilizing agents used for the chemical reduction of Ag NPs are usually toxic and may cause water pollution.In this work,Ag NPs(31.2 nm in diameter)were prepared using the extract of straw,an agricultural waste,as the reducing and stabilizing agent.Experimental analysis revealed that the straw extract contained lignin,the structure of which possesses phenolic hydroxyl and methoxy groups that facilitate the reduction of silver salts into Ag NPs.The surfaces of Ag NPs were negatively charged due to the encapsulation of a thin layer of lignin molecules that prevented their aggregation.After the prepared Ag NPs were added to the precursor solution of acrylamide,free radical polymerization was triggered without the need for extra heating or light irradiation,resulting in the rapid formation of an Ag NP-polyacrylamide composite hydrogel.The inhibition zone test proved that the composite hydrogel possessed excellent antibacterial ability due to the presence of Ag NPs.The prepared hydrogel may have potential applications in the fabrication of biomedical materials,such as antibacterial dressings.展开更多
BACKGROUND This case report describes a protocol developed by Danaun Medical Clinic for the introduction of a pioneering intervention comprising intravenous human placen-tal extract(HPE)therapy to improve the liver fu...BACKGROUND This case report describes a protocol developed by Danaun Medical Clinic for the introduction of a pioneering intervention comprising intravenous human placen-tal extract(HPE)therapy to improve the liver function of patients with chronic liver disease(CLD).CASE SUMMARY This study involved data from patients whose chief complaint was reduced quality of life attributable to CLD.The new treatment approach resulted in improvements in the liver function and fatty liver of 30 patients with CLD.Im-provements were observed using abdominal ultrasonography.Unlike traditional methods,this protocol provided more sustainable and meaningful results.Treat-ment with 10 mL of HPE administered intravenously once or twice per week significantly improved liver function.The observed improvements in fatty liver and liver function suggest the utility of this approach for the management of patients with CLD.CONCLUSION This case series highlights the potential of innovative treatments for patients with CLD that could improve the quality of life of the patients.展开更多
As energy demand increases,the depth of mining is increasing,and methane disasters grow more serious,efficient extraction of methane is the ultimate method of preventing and controlling methane disasters.The objective...As energy demand increases,the depth of mining is increasing,and methane disasters grow more serious,efficient extraction of methane is the ultimate method of preventing and controlling methane disasters.The objectives for this research are to explore the efficiency of N_(2) injection to enhance gas extraction from coal seams(N_(2)-ECGE)and its impact on coal seam permeability.By developing a fluid-solid coupling model and using COMSOL Multiphysics to perform numerical simulations,the changes in gas pressure,methane content,gas production,output rate and permeability of coal seams were comparatively analyzed under the two methods of direct extraction and N_(2)-ECGE.The research results show that N_(2)-ECGE can significantly improve the coal seam gas pressure and reduce the coal seam CH_(4) content,and the larger the N_(2) injection pressure the more significant the reduction effect.Meanwhile,N_(2)-ECGE can significantly increase the CH_(4) extraction and output rate,and the increase of N_(2) pressure further improves the extraction efficiency.In addition,the pressure of nitrogen injection has a remarkable effect on coal seam permeability,high pressure of nitrogen injection can increase the permeability in the time of no disturbance,but the rate of permeability decreases more quickly after disturbed.The effect of strain due to adsorption desorption on coal seam permeability dominates.Despite model construction limitations,this research offers essential theoretical and practical direction for N_(2) injection to enhance the permeability evolution law of coal seam gas extraction process.展开更多
The World Wide Web provides a wealth of information about everything, including contemporary audio and visual art events, which are discussed on media outlets, blogs, and specialized websites alike. This information m...The World Wide Web provides a wealth of information about everything, including contemporary audio and visual art events, which are discussed on media outlets, blogs, and specialized websites alike. This information may become a robust source of real-world data, which may form the basis of an objective data-driven analysis. In this study, a methodology for collecting information about audio and visual art events in an automated manner from a large array of websites is presented in detail. This process uses cutting edge Semantic Web, Web Search and Generative AI technologies to convert website documents into a collection of structured data. The value of the methodology is demonstrated by creating a large dataset concerning audiovisual events in Greece. The collected information includes event characteristics, estimated metrics based on their text descriptions, outreach metrics based on the media that reported them, and a multi-layered classification of these events based on their type, subjects and methods used. This dataset is openly provided to the general and academic public through a Web application. Moreover, each event’s outreach is evaluated using these quantitative metrics, the results are analyzed with an emphasis on classification popularity and useful conclusions are drawn concerning the importance of artistic subjects, methods, and media.展开更多
Photonic crystal surface emitting lasers(PCSELs)utilize the Bragg diffraction of two-dimensional photonic crystals to achieve a single-mode output with a high power and a small divergence angle,and has recently attrac...Photonic crystal surface emitting lasers(PCSELs)utilize the Bragg diffraction of two-dimensional photonic crystals to achieve a single-mode output with a high power and a small divergence angle,and has recently attracted much attention^([1−3]).In 2023,Kyoto University reported GaAs-based 945 nm PCSELs with a continuous-wave(CW)single-mode output power of exceeding 50 W,and a narrow beam divergence angle of 0.05°,demonstrating a brightness of 1 GW·cm^(−2)·sr^(−1),which rivals those of the existing bulky lasers^([4]).展开更多
AIM:To review recent innovations,challenges,and applications of small incision lenticule extraction(SMILE)extracted lenticule for treating ocular disorders.METHODS:A literature review was performed in the PubMed datab...AIM:To review recent innovations,challenges,and applications of small incision lenticule extraction(SMILE)extracted lenticule for treating ocular disorders.METHODS:A literature review was performed in the PubMed database,which was last updated on 30 December 2021.There was no limit regarding language.The authors evaluated the reference lists of the collected papers to find any relevant research.RESULTS:Due to the simplicity and accuracy of modern femtosecond lasers and the extensive development of SMILE surgery,many healthy human corneal stromal lenticules were extracted during surgery,motivating some professionals to investigate the SMILE lenticule reusability in different ocular disorders.In addition,new approaches had been developed to preserve,modify,and bioengineer the corneal stroma,leading to the optimal use of discarded byproducts such as lenticules from SMILE surgery.The lenticules can be effectively re-implanted into the autologous or allogenic corneas of human subjects to treat refractive errors,corneal ectasia,and corneal perforation and serve as a patch graft for glaucoma drainage devices with better cosmetic outcomes.CONCLUSION:SMILE-extracted lenticules could be a viable alternative to human donor corneal tissue.展开更多
Chitosan films with propolis aqueous extract were obtained in order to improve the antioxidant capacity of the materials.Likewise,oleic acid(OA)was also incorporated to enhance the film hydrophobicity,with and without...Chitosan films with propolis aqueous extract were obtained in order to improve the antioxidant capacity of the materials.Likewise,oleic acid(OA)was also incorporated to enhance the film hydrophobicity,with and without previous infusion with propolis,to extract other potentially active compounds.The propolis extracts and the chitosan film-forming dispersions were characterised as to their particle size distribution,zeta potential and rheological behaviour.Chitosan-based films with aqueous extract and with oleic acid,containing or not propolis compounds,were obtained and characterised as to their microstructure,mechanical,barrier and optical properties and antioxidant capacity in order to evaluate their ability to extend the food shelf life.The propolis compounds from the aqueous extract notably modified the chitosan conformation and charge density of chitosan molecules,giving rise to more folded chains with a milder viscous effect.These changes in the polymer gave rise to a coarser film microstructure,which exhibited greater stiffness,and less stretchability and resistance to break,but a greater barrier capacity to water vapour and oxygen.These films had a ten-fold greater antioxidant capacity,thus having great potential to preserve food from oxidative spoilage.The incorporation of OA,containing or not propolis compounds,into these films reduced the film stiffness and resistance to break,and led to a highly enhanced oxygen permeability without there being any notable changes in either the water vapour barrier capacity or antioxidant power.展开更多
Introduction: Mechanism of male androgenic alopecia (MAGA) is complex and leads to an excessive hair shedding and decreased hair density. Oral, topical, and injectable autologous treatments demonstrate ability to stim...Introduction: Mechanism of male androgenic alopecia (MAGA) is complex and leads to an excessive hair shedding and decreased hair density. Oral, topical, and injectable autologous treatments demonstrate ability to stimulate hair re-growth, but the response is suboptimal or plateaus off. Synthetic combination of the peptide complex and hyaluronic acid (P-HA) demonstrated hair regrowth in alopecia patients. Electronically-operated pneumatic injections (EPI) generate micro-trauma in the dermis and under wound-healing conditions may enhance regeneration effect of P-HA. Methods: Subjects seeking improvement of their male pattern hair loss (Hamilton-Norwood type 2-4) received the P-HA treatments through EPI. The course included 4 treatments every two weeks over the 8-week period. In 6 months, the hair growth was assessed comparative to baseline by global clinical photography and digital phototrichograms. The treatment safety and tolerability were documented through the whole study period. Results: Twelve men (30-45 years old) completed the treatment course with high tolerability and without adverse events. Post-treatment assessment of the previously bald areas showed improved coverage on the clinical photographs. The phototrichograms demonstrated statistically significant increase in terminal hair density by 36%, cumulative hair thickness by 37%, and follicular units by 20%;all contributing to a 38% increase in cumulated hair density (all p Conclusion: Electronic pneumatic injections are well tolerated and can be safely used for the needle-free administration of the peptide-hyaluronic acid combination in MAGA therapy. We achieved significant hair re-densification in the balding scalp. The exact role of the EPI-induced impact in the hair re-growth mechanism remains to be ascertained. .展开更多
A resident time model is proposed to evaluate the performance of agitated extraction columns. In this model, the resident time of dispersed drops is simulated with the discrete phase modeling, where the continuous pha...A resident time model is proposed to evaluate the performance of agitated extraction columns. In this model, the resident time of dispersed drops is simulated with the discrete phase modeling, where the continuous phase and the dispersed phase （drops） are described by the single-phase Navier-Stokes （turbulence） model and Lagrangian model, respectively. The interaction of dispersed phase and continuous phase is neglected for the low concentration of drop in the cases studied. The statistical parameters of drops （the average resident time and standard deviation） under different operation conditions are computed for four columns. The relation of the above statistical parameters with the performance of columns is discussed and the criterions for an optimal compartment are outlined. Our results indicate that the resident time model is useful to evaluate the performance and optimize the design of extraction columns.展开更多
One of the biggest dangers to society today is terrorism, where attacks have become one of the most significantrisks to international peace and national security. Big data, information analysis, and artificial intelli...One of the biggest dangers to society today is terrorism, where attacks have become one of the most significantrisks to international peace and national security. Big data, information analysis, and artificial intelligence (AI) havebecome the basis for making strategic decisions in many sensitive areas, such as fraud detection, risk management,medical diagnosis, and counter-terrorism. However, there is still a need to assess how terrorist attacks are related,initiated, and detected. For this purpose, we propose a novel framework for classifying and predicting terroristattacks. The proposed framework posits that neglected text attributes included in the Global Terrorism Database(GTD) can influence the accuracy of the model’s classification of terrorist attacks, where each part of the datacan provide vital information to enrich the ability of classifier learning. Each data point in a multiclass taxonomyhas one or more tags attached to it, referred as “related tags.” We applied machine learning classifiers to classifyterrorist attack incidents obtained from the GTD. A transformer-based technique called DistilBERT extracts andlearns contextual features from text attributes to acquiremore information from text data. The extracted contextualfeatures are combined with the “key features” of the dataset and used to perform the final classification. Thestudy explored different experimental setups with various classifiers to evaluate the model’s performance. Theexperimental results show that the proposed framework outperforms the latest techniques for classifying terroristattacks with an accuracy of 98.7% using a combined feature set and extreme gradient boosting classifier.展开更多
Doxorubicin(DOX)is a widely employed tumor therapy,yet its substantial toxic side effects pose a considerable challenge.Bletilla striata has demonstrated efficacy in preventing and treating these toxic side effects in...Doxorubicin(DOX)is a widely employed tumor therapy,yet its substantial toxic side effects pose a considerable challenge.Bletilla striata has demonstrated efficacy in preventing and treating these toxic side effects in clinical practice,with polysaccharides identified as the principal active component.In the present study,16 fractions of B.striata polysaccharides(BsPs)were extracted using diverse methods,including hot-water extraction(HWE),ultrasonic-assisted extraction(UAE),enzyme-assisted extraction(EAE),dilute acid-water extraction(ACWE),and dilute alkali-water extraction(ALWE).These extractions were subsequently precipitated at final ethanol concentrations of 80%and 95%,respectively.The investigation encompassed yields,total carbohydrate content(TCC),total protein content(TPC),preliminary structural properties,and anti-DOX myocardial cytotoxic activity.Results indicated that the extraction method significantly influenced the physicochemical properties,associated functional properties,and anti-DOX myocardial cytotoxic activity of BsPs.HWE and UAE yielded higher BsPs quantities.The relative molecular weight(RMW)distribution of BsPs differed notably between HWE or UAE,EAE,ACWE,and ALWE.The RMW of primary BsPs obtained from HWE and UAE(1.9×10^(7)-1.7×10^(7) Da)exceeded that from EAE(7.5×10^(3)-2.8×10^(4) Da)and ALWE(5.1×10^(4)-1.7×10^(4) Da),with smaller molecular weights primarily precipitated by higher ethanol concentrations.BsPs were composed of Man and Glu,with partial fractions containing small amounts of Gal or Ara,displaying varying molar ratios.Notably,BsPs from ACWE exhibited the most significant structural differences,lacking 1,4-α-D-Glcp and a triple-helical structure.Furthermore,BsPs obtained from HWE,UAE,and EAE demonstrated heightened anti-DOX myocardial cytotoxic activity compared to other methods.This study underscored the influence of extraction methods on BsPs’structure and myocardial protective activity,offering a foundation for exploring structural diversity and employing specific extraction methods to extract polysaccharides with robust myocardial protective properties efficiently.展开更多
In the international shipping industry, digital intelligence transformation has become essential, with both governments and enterprises actively working to integrate diverse datasets. The domain of maritime and shippi...In the international shipping industry, digital intelligence transformation has become essential, with both governments and enterprises actively working to integrate diverse datasets. The domain of maritime and shipping is characterized by a vast array of document types, filled with complex, large-scale, and often chaotic knowledge and relationships. Effectively managing these documents is crucial for developing a Large Language Model (LLM) in the maritime domain, enabling practitioners to access and leverage valuable information. A Knowledge Graph (KG) offers a state-of-the-art solution for enhancing knowledge retrieval, providing more accurate responses and enabling context-aware reasoning. This paper presents a framework for utilizing maritime and shipping documents to construct a knowledge graph using GraphRAG, a hybrid tool combining graph-based retrieval and generation capabilities. The extraction of entities and relationships from these documents and the KG construction process are detailed. Furthermore, the KG is integrated with an LLM to develop a Q&A system, demonstrating that the system significantly improves answer accuracy compared to traditional LLMs. Additionally, the KG construction process is up to 50% faster than conventional LLM-based approaches, underscoring the efficiency of our method. This study provides a promising approach to digital intelligence in shipping, advancing knowledge accessibility and decision-making.展开更多
Solvent extraction is the main method used to separate and purify rare earth elements.In the process of rare earths extraction,emulsification often generated due to the instability of the aqueous and organic phases or...Solvent extraction is the main method used to separate and purify rare earth elements.In the process of rare earths extraction,emulsification often generated due to the instability of the aqueous and organic phases or improper operating conditions.Once emulsification occurs,it would not only lead to low rare earths recovery efficiency,small product quantities,high production costs and the losing of extractant and rare earth resources,but also result in serious environmental pollution.Therefore,it is very important to study the micro-mechanisms of emulsification and establish new methods to prevent emulsification at the source.In this paper,possible factors resulting in emulsification,such as the compositions and properties of the organic and aqueous phases,the operating conditions of the rare earths extraction are reviewed.The micro-mechanisms of emulsification are summarized basing on the microscopic structures in the bulk phase,aggregations of the extractants at the organic-aqueous interface,spectral characterizations and computational simulations.On this basis,new formation mechanisms are proposed for emulsification.Preliminary explorations are employed to verify the correctness of these new viewpoints.Finally,future directions for studies of the emulsification micro-mechanism are proposed.This study provides a theoretical basis for further understanding the micro-mechanisms of interfacial instability resulting in emulsification in the process of rare earths extraction.展开更多
Solvent-extracted fractions of six Indian coal samples of different ranks were investigated using multiple geochemical,petrological and spectroscopic proxies and an attempt was made to indicate possible fingerprint re...Solvent-extracted fractions of six Indian coal samples of different ranks were investigated using multiple geochemical,petrological and spectroscopic proxies and an attempt was made to indicate possible fingerprint regions for different polycyclic aromatic hydrocarbons(PAH)with the help of excitation-emission matrix(EEM).In this study,for the very first time,the influence of rank and maturation of organic matter in the characterisation of coal solvent-extracts from Indian coals were perceived from the viewpoint of fluorescence EEM.Vitrinite reflectance(VR_(0))values were used to determine the general ranks of the original coal samples viz.lignite,subbituminous,bituminous and anthracite.Different fluorescence peak regions corresponding to different fused aromatic ring(FAR)systems were delineated using the EEM and their indicative depositional environments could be inferred.Our observations indicate that solvent-extracted fractions of low rank coals comprise of a larger number of shorter carbon chains compared to the other samples.For the low rank coal samples,the solvent-extracts show a strong humic influence and the presence of smaller PAH rings while for the medium rank coals,the extracted fractions tend to show a more bimodal distribution of PAHs,possibly comprising of different sized PAHs.Higher fluorescence sensitivity and quick response of smaller PAHs impart a singular centralised region in the EEM for the low rank coal samples while interference in the fluorescence of differently sized PAHs indicate a multimodal distribution of the fluorophores in the medium rank coals.The high rank coal used in this study shows a bimodal distribution with very low intensity of the peaks,indicating the low abundance of extractable macromolecules,possibly as a result of deformation.展开更多
The production and consumption of avocado pears generates tons of wastes, mainly the pear peels which are usually discarded, although they have been reported to contain important phyto-chemicals with biological activi...The production and consumption of avocado pears generates tons of wastes, mainly the pear peels which are usually discarded, although they have been reported to contain important phyto-chemicals with biological activities. The adverse health effect associated with the consumption of saturated lipid based foods has ignited research on reformulation of lipid based foods to eliminate Trans Fatty Acids (TFAs). This study was thus aimed at the extraction and characterization of oil from Avocado Peels (APO) and evaluation of the quality of margarine produced from it. Five verities of pear were used for oil extraction by soxhlet method and physiochemical, oxidative, functional and antioxidant characterization was done. Margarines were formulated using a central composite design using oil blends of APO and Virgin Coconut Oil (VCO) with an oil ratio of 10:90, 40:60, 70:30 respectively, varied blending speed, blending time, and chitosan concentration. Samples were characterized and the effect of process parameters on the physiochemical and functional properties of the margarine studied. Optimized conditions were used to produce samples for sensory evaluation. Color, spreadability, aroma, taste and general acceptability was evaluated using ranking difference test. The results showed that the yield, density, and iodine values of APOs oils ranged from 14.91 ± 0.18 to 11.76 ± 0.46;0.93 ± 0.001 to 0.99 ± 0.1;46.63 ± 1.70 to 52.4 ± 0.63, their acid values, TBA and PV values ranged from 1.42 ± 0.39 to 1.97 ± 0.5;0.11 ± 0.002 to 0.18 ± 0.04;and 2.72 ± 0.14 to 4.43 ± 0.36 respectively, with Brogdon avocado peel variety having the overall best properties prepared blends of trans-free APO margarines showed that increase in APO ratio decreased melting point, increased oxidative stability and reduced moisture content of margarine samples. Chitosan addition leads to decrease moisture content and increase functional properties. VCO lead to increase in phenolic and flavonoid content of the margarines. Samples were spreadable and palatable with R20 being most palatable and the most accepted being R26 with a mean score of 7.07 ± 0.70. Decrease in color intensity increased acceptability. This study therefore demonstrated that avocado peel waste biomass can be valorized by using it as raw material for oil extraction, which can serve as good material for the production of trans-free margarines with good oxidative stability, functional and antioxidant properties.展开更多
The inhibitory properties of rapeseed cake meal extract(RCME)on the corrosion of cold rolled steel(CRS)in trichloroacetic acid(TCA)were systematically investigated using gravimetric,electrochemical,surface characteriz...The inhibitory properties of rapeseed cake meal extract(RCME)on the corrosion of cold rolled steel(CRS)in trichloroacetic acid(TCA)were systematically investigated using gravimetric,electrochemical,surface characterizations and theoretical calculations.The results demonstrate that RCME exhibits excellent inhibitory performance with a maximum inhibition efficiency of 92.7%for 100 mg L−1 RCME at 20℃.The adsorption of RCME obeys Langmuir isotherm at 20 and 30℃,Temkin isotherm at 40℃,and Freundlich isotherm at 50℃.RCME acts as a cathodic inhibitor.The charge transfer resistance is increased with the addition of RCME,while the double-layer capacitance decreases.SEM,AFM,CLSM,XPS,XRD and TOF-SIMS analyses confirm that the active components in RCME adsorb onto the surface of CRS,forming a protective film that effectively inhibits the corrosion of CRS by TCA.Along with the increase in the concentration of RCME,the surface tension of the inhibited solution gradually decreases,while the electrical conductivity increases before stabilizing.HPLC-MS and FTIR analyses reveal rutin,linolenic acid,linoleic acid and adenine are the effective substances in RCME.Quantum chemical(QC)calculations and molecular dynamic(MD)simulations indicate that the active centers of the effective inhibitor molecules are predominantly located on benzene rings,O-or N-containing heterocyclic rings,and functional groups such as C=O and C=C.Additionally,their main chains adsorb onto the Fe(001)surface in an approximately flat manner,involving both chemical and physical adsorption processes.展开更多
Identification of the most appropriate chemically extractable pool for evaluating Cd and Pb availability remains elusive,hindering accurate assessment on environmental risks and effectiveness of remediation strategies...Identification of the most appropriate chemically extractable pool for evaluating Cd and Pb availability remains elusive,hindering accurate assessment on environmental risks and effectiveness of remediation strategies.This study evaluated the feasibility of European Community Bureau of Reference(BCR)sequential extraction,Ca(NO_(3))_(2)extraction,and water extraction on assessing Cd and Pb availability in agricultural soil amended with slaked lime,magnesium hydroxide,corn stover biochar,and calcium dihydrogen phosphate.Moreover,the enriched isotope tracing technique(^(112)Cd and^(206)Pb)was employed to evaluate the aging process of newly introduced Cd and Pbwithin 56 days’incubation.Results demonstrated that extractable pools by BCR and Ca(NO_(3))_(2)extraction were little impacted by amendments and showed little correlation with soil pH.This is notable because soil pH is closely linked to metal availability,indicating these extraction methods may not adequately reflect metal availability.Conversely,water-soluble concentrations of Cd and Pb were markedly influenced by amendments and exhibited strong correlations with pH(Pearson’s r:-0.908 to-0.825,P<0.001),suggesting water extraction as a more sensitive approach.Furthermore,newly introduced metals underwent a more evident aging process as demonstrated by acid-soluble and water-soluble pools.Additionally,water-soluble concentrations of essential metals were impacted by soil amendments,raising caution on their potential effects on plant growth.These findings suggest water extraction as a promising and attractive method to evaluate Cd and Pb availability,which will help provide assessment guidance for environmental risks caused by heavy metals and develop efficient remediation strategies.展开更多
BACKGROUND A total of 100 patients diagnosed with mixed hemorrhoids from October 2022 to September 2023 in our hospital were randomly divided into groups by dice rolling and compared with the efficacy of different tre...BACKGROUND A total of 100 patients diagnosed with mixed hemorrhoids from October 2022 to September 2023 in our hospital were randomly divided into groups by dice rolling and compared with the efficacy of different treatment options.AIM To analyze the clinical effect and prognosis of mixed hemorrhoids treated with polidocanol injection combined with automatic elastic thread ligation operation(RPH).METHODS A total of 100 patients with mixed hemorrhoids who visited our hospital from October 2022 to September 2023 were selected and randomly divided into the control group(n=50)and the treatment group(n=50)by rolling the dice.The procedure for prolapse and hemorrhoids(PPH)was adopted in the control group,while polidocanol foam injection+RPH was adopted in the treatment group.The therapeutic effects,operation time,wound healing time,hospital stay,pain situation(24 hours post-operative pain score,first defecation pain score),quality of life(QOL),incidence of complications(post-operative hemorrhage,edema,infection),incidence of anal stenosis 3 months post-operatively and recurrence rate 1 year post-operatively of the two groups were compared.RESULTS Compared with the control group,the total effective rate of treatment group was higher,and the difference was significant(P<0.05).The operation time/wound healing time/hospital stay in the treatment group were shorter than those in the control group(P<0.05).The pain scores at 24 hours after operation/first defecation pain score of the treatment group was significantly lower than those in the control group(P<0.05).After surgery,the QOL scores of the two groups decreased,with the treatment group having higher scores than that of the control group(P<0.05).Compared with the control group,the incidence of postoperative complications in the treatment group was lower,and the difference was significant(P<0.05);However,there was no significant difference in the incidence of postoperative bleeding between the two groups(P>0.05);There was no significant difference in the incidence of anal stenosis 3 months after operation and the recurrence rate 1 year after operation between the two groups(P>0.05).CONCLUSION For patients with mixed hemorrhoids,the therapeutic effect achieved by using polidocanol injection combined with RPH was better.The wounds of the patients healed faster,the postoperative pain was milder,QOL improved,and the incidence of complications was lower,and the short-term and long-term prognosis was good.展开更多
During high-speed rotation,the surface of aeronautic spiral bevel gears will generate significant pressure and viscous forces,which will cause a certain amount of windage power loss and reduce the efficiency of the tr...During high-speed rotation,the surface of aeronautic spiral bevel gears will generate significant pressure and viscous forces,which will cause a certain amount of windage power loss and reduce the efficiency of the transmission system.Based on the computational fluid dynamics,this paper analyzes the windage power loss of a single spiral bevel gear and a spiral bevel gear pair under oil injection lubrication.In addition,the shroud is used to suppress gear windage loss,and the clearance size and opening angle of the designed shroud are optimized.Finally,by comparing and analyzing the experimental results,the following conclusions were obtained:(1)For a single gear,the speed is the most important factor affecting windage loss,followed by the hand of spiral,and rotation direction;(2)For gear pairs,under oil injection lubrication,the input speed has the greatest impact on windage power loss,followed by the influence of oil injection port speed,temperature and oil injection port pressure;(3)Installing a shroud is an effective method to reduce windage power loss;(4)In the pure air phase,the smaller the clearance between the shroud and the gear surface,and the smaller the radial direction between the shroud and the shaft,the better the effect of reducing windage;(5)In the two-phase flow of oil and gas,it is necessary to design oil drainage holes on the shroud to ensure the smooth discharge of lubricating oil and improve the drag reduction effect.展开更多
Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in China.In vine tea processing,a large amount of broken tea is produced,which has low commercial value.Methods:This study investigat...Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in China.In vine tea processing,a large amount of broken tea is produced,which has low commercial value.Methods:This study investigates the influence of different extraction methods(room temperature water extraction,boiling water extraction,ultrasonic-assisted room temperature water extraction,and ultrasonic-assisted boiling water extraction,referred to as room temperature water extraction(RE),boiling water extraction(BE),ultrasonic assistance at room temperature water extraction(URE),and ultrasonic assistance in boiling water extraction(UBE))on the yield,dihydromyricetin(DMY)content,free amino acid composition,volatile aroma components,and antioxidant properties of vine tea extracts.Results:A notable influence of extraction temperature on the yield of vine tea extracts(P<0.05),with BE yielding the highest at 43.13±0.26%,higher than that of RE(34.29±0.81%).Ultrasound-assisted extraction significantly increased the DMY content of the extracts(P<0.05),whereas DMY content in the RE extracts was 59.94±1.70%,that of URE reached 66.14±2.78%.Analysis revealed 17 amino acids,with L-serine and aspartic acid being the most abundant in the extracts,nevertheless ultrasound-assisted extraction reduced total free amino acid content.Gas chromatography-mass spectrometry analysis demonstrated an increase in the diversity and quantity of compounds in the vine tea water extracts obtained through ultrasonic-assisted extraction.Specifically,69 and 68 volatile compounds were found in URE and UBE extracts,which were higher than the number found in RE and BE extracts.In vitro,antioxidant activity assessments revealed varying antioxidant capacities among different extraction methods,with RE exhibiting the highest DPPH scavenging rate,URE leading in ABTS•+free radical scavenging,and BE demonstrating superior ferric ion reducing antioxidant activity.Conclusion:The findings suggest that extraction methods significantly influence the chemical composition and antioxidant properties of vine tea extracts.Ultrasonic-assisted extraction proved instrumental in elevating the DMY content in vine tea extracts,thereby enriching its flavor profile while maintaining its antioxidant properties.展开更多
基金financially supported by the National Natural Science Foundation of China(No.52203209)the State Key Laboratory of Solid Waste Reuse for Building Materials,China(No.SWR-2022-009)the Fundamental Research Funds for the Central Universities,China(No.FRF-IDRY22-012)。
文摘Silver nanoparticles(Ag NPs)have attracted attention in the field of biomaterials due to their excellent antibacterial property.However,the reducing and stabilizing agents used for the chemical reduction of Ag NPs are usually toxic and may cause water pollution.In this work,Ag NPs(31.2 nm in diameter)were prepared using the extract of straw,an agricultural waste,as the reducing and stabilizing agent.Experimental analysis revealed that the straw extract contained lignin,the structure of which possesses phenolic hydroxyl and methoxy groups that facilitate the reduction of silver salts into Ag NPs.The surfaces of Ag NPs were negatively charged due to the encapsulation of a thin layer of lignin molecules that prevented their aggregation.After the prepared Ag NPs were added to the precursor solution of acrylamide,free radical polymerization was triggered without the need for extra heating or light irradiation,resulting in the rapid formation of an Ag NP-polyacrylamide composite hydrogel.The inhibition zone test proved that the composite hydrogel possessed excellent antibacterial ability due to the presence of Ag NPs.The prepared hydrogel may have potential applications in the fabrication of biomedical materials,such as antibacterial dressings.
文摘BACKGROUND This case report describes a protocol developed by Danaun Medical Clinic for the introduction of a pioneering intervention comprising intravenous human placen-tal extract(HPE)therapy to improve the liver function of patients with chronic liver disease(CLD).CASE SUMMARY This study involved data from patients whose chief complaint was reduced quality of life attributable to CLD.The new treatment approach resulted in improvements in the liver function and fatty liver of 30 patients with CLD.Im-provements were observed using abdominal ultrasonography.Unlike traditional methods,this protocol provided more sustainable and meaningful results.Treat-ment with 10 mL of HPE administered intravenously once or twice per week significantly improved liver function.The observed improvements in fatty liver and liver function suggest the utility of this approach for the management of patients with CLD.CONCLUSION This case series highlights the potential of innovative treatments for patients with CLD that could improve the quality of life of the patients.
基金supported by the National Natural Science Foundation of China(52374249,52130409,52121003)the National Key R&D Program(2023YFC3009003)+1 种基金the Basic Research Business Fees for Central Universities(2024JCCXAQ01)Open Fund of State Key Laboratory of Coal Mine Disaster Dynamics and Control(2011DA105287-FW202303).
文摘As energy demand increases,the depth of mining is increasing,and methane disasters grow more serious,efficient extraction of methane is the ultimate method of preventing and controlling methane disasters.The objectives for this research are to explore the efficiency of N_(2) injection to enhance gas extraction from coal seams(N_(2)-ECGE)and its impact on coal seam permeability.By developing a fluid-solid coupling model and using COMSOL Multiphysics to perform numerical simulations,the changes in gas pressure,methane content,gas production,output rate and permeability of coal seams were comparatively analyzed under the two methods of direct extraction and N_(2)-ECGE.The research results show that N_(2)-ECGE can significantly improve the coal seam gas pressure and reduce the coal seam CH_(4) content,and the larger the N_(2) injection pressure the more significant the reduction effect.Meanwhile,N_(2)-ECGE can significantly increase the CH_(4) extraction and output rate,and the increase of N_(2) pressure further improves the extraction efficiency.In addition,the pressure of nitrogen injection has a remarkable effect on coal seam permeability,high pressure of nitrogen injection can increase the permeability in the time of no disturbance,but the rate of permeability decreases more quickly after disturbed.The effect of strain due to adsorption desorption on coal seam permeability dominates.Despite model construction limitations,this research offers essential theoretical and practical direction for N_(2) injection to enhance the permeability evolution law of coal seam gas extraction process.
文摘The World Wide Web provides a wealth of information about everything, including contemporary audio and visual art events, which are discussed on media outlets, blogs, and specialized websites alike. This information may become a robust source of real-world data, which may form the basis of an objective data-driven analysis. In this study, a methodology for collecting information about audio and visual art events in an automated manner from a large array of websites is presented in detail. This process uses cutting edge Semantic Web, Web Search and Generative AI technologies to convert website documents into a collection of structured data. The value of the methodology is demonstrated by creating a large dataset concerning audiovisual events in Greece. The collected information includes event characteristics, estimated metrics based on their text descriptions, outreach metrics based on the media that reported them, and a multi-layered classification of these events based on their type, subjects and methods used. This dataset is openly provided to the general and academic public through a Web application. Moreover, each event’s outreach is evaluated using these quantitative metrics, the results are analyzed with an emphasis on classification popularity and useful conclusions are drawn concerning the importance of artistic subjects, methods, and media.
基金funded by National Key R&D Program of China(Grant Nos.2024YFB3612200,2023YFB3609601,2022YFB3604300,2022YFB2802801,2022YFB3604802)Natural Science Foundation of China(Grant Nos.U24A20300,62174174,62274177,62275263,62325406,62374172,62304242,62304240,62404241)+4 种基金Youth Innovation Promotion Association of CAS(Grant Nos.2022323 and 2022324)Key R&D Program of Jiangsu Province(Grant No.BE2023018-2)Basic Research Program of Jiangsu(Grant No.BK20240126)Suzhou Science and Technology Program(Grant Nos.SYC2022089,ZXL2024379,and ZXL2024376)Guangdong Basic and Applied Basic Research Foundation(Grant Nos.2022A1515110482 and 2022A1515110004).
文摘Photonic crystal surface emitting lasers(PCSELs)utilize the Bragg diffraction of two-dimensional photonic crystals to achieve a single-mode output with a high power and a small divergence angle,and has recently attracted much attention^([1−3]).In 2023,Kyoto University reported GaAs-based 945 nm PCSELs with a continuous-wave(CW)single-mode output power of exceeding 50 W,and a narrow beam divergence angle of 0.05°,demonstrating a brightness of 1 GW·cm^(−2)·sr^(−1),which rivals those of the existing bulky lasers^([4]).
文摘AIM:To review recent innovations,challenges,and applications of small incision lenticule extraction(SMILE)extracted lenticule for treating ocular disorders.METHODS:A literature review was performed in the PubMed database,which was last updated on 30 December 2021.There was no limit regarding language.The authors evaluated the reference lists of the collected papers to find any relevant research.RESULTS:Due to the simplicity and accuracy of modern femtosecond lasers and the extensive development of SMILE surgery,many healthy human corneal stromal lenticules were extracted during surgery,motivating some professionals to investigate the SMILE lenticule reusability in different ocular disorders.In addition,new approaches had been developed to preserve,modify,and bioengineer the corneal stroma,leading to the optimal use of discarded byproducts such as lenticules from SMILE surgery.The lenticules can be effectively re-implanted into the autologous or allogenic corneas of human subjects to treat refractive errors,corneal ectasia,and corneal perforation and serve as a patch graft for glaucoma drainage devices with better cosmetic outcomes.CONCLUSION:SMILE-extracted lenticules could be a viable alternative to human donor corneal tissue.
基金supported by Generalitat Valenciana(Valencia,Spain)(Grant No.CIPROM/2021/071).
文摘Chitosan films with propolis aqueous extract were obtained in order to improve the antioxidant capacity of the materials.Likewise,oleic acid(OA)was also incorporated to enhance the film hydrophobicity,with and without previous infusion with propolis,to extract other potentially active compounds.The propolis extracts and the chitosan film-forming dispersions were characterised as to their particle size distribution,zeta potential and rheological behaviour.Chitosan-based films with aqueous extract and with oleic acid,containing or not propolis compounds,were obtained and characterised as to their microstructure,mechanical,barrier and optical properties and antioxidant capacity in order to evaluate their ability to extend the food shelf life.The propolis compounds from the aqueous extract notably modified the chitosan conformation and charge density of chitosan molecules,giving rise to more folded chains with a milder viscous effect.These changes in the polymer gave rise to a coarser film microstructure,which exhibited greater stiffness,and less stretchability and resistance to break,but a greater barrier capacity to water vapour and oxygen.These films had a ten-fold greater antioxidant capacity,thus having great potential to preserve food from oxidative spoilage.The incorporation of OA,containing or not propolis compounds,into these films reduced the film stiffness and resistance to break,and led to a highly enhanced oxygen permeability without there being any notable changes in either the water vapour barrier capacity or antioxidant power.
文摘Introduction: Mechanism of male androgenic alopecia (MAGA) is complex and leads to an excessive hair shedding and decreased hair density. Oral, topical, and injectable autologous treatments demonstrate ability to stimulate hair re-growth, but the response is suboptimal or plateaus off. Synthetic combination of the peptide complex and hyaluronic acid (P-HA) demonstrated hair regrowth in alopecia patients. Electronically-operated pneumatic injections (EPI) generate micro-trauma in the dermis and under wound-healing conditions may enhance regeneration effect of P-HA. Methods: Subjects seeking improvement of their male pattern hair loss (Hamilton-Norwood type 2-4) received the P-HA treatments through EPI. The course included 4 treatments every two weeks over the 8-week period. In 6 months, the hair growth was assessed comparative to baseline by global clinical photography and digital phototrichograms. The treatment safety and tolerability were documented through the whole study period. Results: Twelve men (30-45 years old) completed the treatment course with high tolerability and without adverse events. Post-treatment assessment of the previously bald areas showed improved coverage on the clinical photographs. The phototrichograms demonstrated statistically significant increase in terminal hair density by 36%, cumulative hair thickness by 37%, and follicular units by 20%;all contributing to a 38% increase in cumulated hair density (all p Conclusion: Electronic pneumatic injections are well tolerated and can be safely used for the needle-free administration of the peptide-hyaluronic acid combination in MAGA therapy. We achieved significant hair re-densification in the balding scalp. The exact role of the EPI-induced impact in the hair re-growth mechanism remains to be ascertained. .
基金Supported by the National Natural Science Foundation of China (No. 20376053).
文摘A resident time model is proposed to evaluate the performance of agitated extraction columns. In this model, the resident time of dispersed drops is simulated with the discrete phase modeling, where the continuous phase and the dispersed phase （drops） are described by the single-phase Navier-Stokes （turbulence） model and Lagrangian model, respectively. The interaction of dispersed phase and continuous phase is neglected for the low concentration of drop in the cases studied. The statistical parameters of drops （the average resident time and standard deviation） under different operation conditions are computed for four columns. The relation of the above statistical parameters with the performance of columns is discussed and the criterions for an optimal compartment are outlined. Our results indicate that the resident time model is useful to evaluate the performance and optimize the design of extraction columns.
文摘One of the biggest dangers to society today is terrorism, where attacks have become one of the most significantrisks to international peace and national security. Big data, information analysis, and artificial intelligence (AI) havebecome the basis for making strategic decisions in many sensitive areas, such as fraud detection, risk management,medical diagnosis, and counter-terrorism. However, there is still a need to assess how terrorist attacks are related,initiated, and detected. For this purpose, we propose a novel framework for classifying and predicting terroristattacks. The proposed framework posits that neglected text attributes included in the Global Terrorism Database(GTD) can influence the accuracy of the model’s classification of terrorist attacks, where each part of the datacan provide vital information to enrich the ability of classifier learning. Each data point in a multiclass taxonomyhas one or more tags attached to it, referred as “related tags.” We applied machine learning classifiers to classifyterrorist attack incidents obtained from the GTD. A transformer-based technique called DistilBERT extracts andlearns contextual features from text attributes to acquiremore information from text data. The extracted contextualfeatures are combined with the “key features” of the dataset and used to perform the final classification. Thestudy explored different experimental setups with various classifiers to evaluate the model’s performance. Theexperimental results show that the proposed framework outperforms the latest techniques for classifying terroristattacks with an accuracy of 98.7% using a combined feature set and extreme gradient boosting classifier.
基金Science and Technology Foundation of Guizhou Province(Grant No.QKHJC-ZK[2023]YB524)Science and Technology Plan Project of Guizhou,China(Grant No.QKPTRC[2019]035)+2 种基金Science and Technology Foundation of Guizhou Province(Grant No.QKH[2019]1346)Science and Technology Department of Zunyi city of Guizhou province of China(Grant No.[2020]7)Undergraduate Training Program for Innovation and Entrepreneurship of Zunyi Medical University(Grant No.S202310661248).
文摘Doxorubicin(DOX)is a widely employed tumor therapy,yet its substantial toxic side effects pose a considerable challenge.Bletilla striata has demonstrated efficacy in preventing and treating these toxic side effects in clinical practice,with polysaccharides identified as the principal active component.In the present study,16 fractions of B.striata polysaccharides(BsPs)were extracted using diverse methods,including hot-water extraction(HWE),ultrasonic-assisted extraction(UAE),enzyme-assisted extraction(EAE),dilute acid-water extraction(ACWE),and dilute alkali-water extraction(ALWE).These extractions were subsequently precipitated at final ethanol concentrations of 80%and 95%,respectively.The investigation encompassed yields,total carbohydrate content(TCC),total protein content(TPC),preliminary structural properties,and anti-DOX myocardial cytotoxic activity.Results indicated that the extraction method significantly influenced the physicochemical properties,associated functional properties,and anti-DOX myocardial cytotoxic activity of BsPs.HWE and UAE yielded higher BsPs quantities.The relative molecular weight(RMW)distribution of BsPs differed notably between HWE or UAE,EAE,ACWE,and ALWE.The RMW of primary BsPs obtained from HWE and UAE(1.9×10^(7)-1.7×10^(7) Da)exceeded that from EAE(7.5×10^(3)-2.8×10^(4) Da)and ALWE(5.1×10^(4)-1.7×10^(4) Da),with smaller molecular weights primarily precipitated by higher ethanol concentrations.BsPs were composed of Man and Glu,with partial fractions containing small amounts of Gal or Ara,displaying varying molar ratios.Notably,BsPs from ACWE exhibited the most significant structural differences,lacking 1,4-α-D-Glcp and a triple-helical structure.Furthermore,BsPs obtained from HWE,UAE,and EAE demonstrated heightened anti-DOX myocardial cytotoxic activity compared to other methods.This study underscored the influence of extraction methods on BsPs’structure and myocardial protective activity,offering a foundation for exploring structural diversity and employing specific extraction methods to extract polysaccharides with robust myocardial protective properties efficiently.
文摘In the international shipping industry, digital intelligence transformation has become essential, with both governments and enterprises actively working to integrate diverse datasets. The domain of maritime and shipping is characterized by a vast array of document types, filled with complex, large-scale, and often chaotic knowledge and relationships. Effectively managing these documents is crucial for developing a Large Language Model (LLM) in the maritime domain, enabling practitioners to access and leverage valuable information. A Knowledge Graph (KG) offers a state-of-the-art solution for enhancing knowledge retrieval, providing more accurate responses and enabling context-aware reasoning. This paper presents a framework for utilizing maritime and shipping documents to construct a knowledge graph using GraphRAG, a hybrid tool combining graph-based retrieval and generation capabilities. The extraction of entities and relationships from these documents and the KG construction process are detailed. Furthermore, the KG is integrated with an LLM to develop a Q&A system, demonstrating that the system significantly improves answer accuracy compared to traditional LLMs. Additionally, the KG construction process is up to 50% faster than conventional LLM-based approaches, underscoring the efficiency of our method. This study provides a promising approach to digital intelligence in shipping, advancing knowledge accessibility and decision-making.
基金Project supported by the National Natural Science Foundation of China(52074031)the Key Research and Development Program of Shandong Province(ZR2021MB051,ZR2020ME256)the Open Project of Key Laboratory of Green Chemical Engineering Process of Ministry of Education(GCP202117)。
文摘Solvent extraction is the main method used to separate and purify rare earth elements.In the process of rare earths extraction,emulsification often generated due to the instability of the aqueous and organic phases or improper operating conditions.Once emulsification occurs,it would not only lead to low rare earths recovery efficiency,small product quantities,high production costs and the losing of extractant and rare earth resources,but also result in serious environmental pollution.Therefore,it is very important to study the micro-mechanisms of emulsification and establish new methods to prevent emulsification at the source.In this paper,possible factors resulting in emulsification,such as the compositions and properties of the organic and aqueous phases,the operating conditions of the rare earths extraction are reviewed.The micro-mechanisms of emulsification are summarized basing on the microscopic structures in the bulk phase,aggregations of the extractants at the organic-aqueous interface,spectral characterizations and computational simulations.On this basis,new formation mechanisms are proposed for emulsification.Preliminary explorations are employed to verify the correctness of these new viewpoints.Finally,future directions for studies of the emulsification micro-mechanism are proposed.This study provides a theoretical basis for further understanding the micro-mechanisms of interfacial instability resulting in emulsification in the process of rare earths extraction.
文摘Solvent-extracted fractions of six Indian coal samples of different ranks were investigated using multiple geochemical,petrological and spectroscopic proxies and an attempt was made to indicate possible fingerprint regions for different polycyclic aromatic hydrocarbons(PAH)with the help of excitation-emission matrix(EEM).In this study,for the very first time,the influence of rank and maturation of organic matter in the characterisation of coal solvent-extracts from Indian coals were perceived from the viewpoint of fluorescence EEM.Vitrinite reflectance(VR_(0))values were used to determine the general ranks of the original coal samples viz.lignite,subbituminous,bituminous and anthracite.Different fluorescence peak regions corresponding to different fused aromatic ring(FAR)systems were delineated using the EEM and their indicative depositional environments could be inferred.Our observations indicate that solvent-extracted fractions of low rank coals comprise of a larger number of shorter carbon chains compared to the other samples.For the low rank coal samples,the solvent-extracts show a strong humic influence and the presence of smaller PAH rings while for the medium rank coals,the extracted fractions tend to show a more bimodal distribution of PAHs,possibly comprising of different sized PAHs.Higher fluorescence sensitivity and quick response of smaller PAHs impart a singular centralised region in the EEM for the low rank coal samples while interference in the fluorescence of differently sized PAHs indicate a multimodal distribution of the fluorophores in the medium rank coals.The high rank coal used in this study shows a bimodal distribution with very low intensity of the peaks,indicating the low abundance of extractable macromolecules,possibly as a result of deformation.
文摘The production and consumption of avocado pears generates tons of wastes, mainly the pear peels which are usually discarded, although they have been reported to contain important phyto-chemicals with biological activities. The adverse health effect associated with the consumption of saturated lipid based foods has ignited research on reformulation of lipid based foods to eliminate Trans Fatty Acids (TFAs). This study was thus aimed at the extraction and characterization of oil from Avocado Peels (APO) and evaluation of the quality of margarine produced from it. Five verities of pear were used for oil extraction by soxhlet method and physiochemical, oxidative, functional and antioxidant characterization was done. Margarines were formulated using a central composite design using oil blends of APO and Virgin Coconut Oil (VCO) with an oil ratio of 10:90, 40:60, 70:30 respectively, varied blending speed, blending time, and chitosan concentration. Samples were characterized and the effect of process parameters on the physiochemical and functional properties of the margarine studied. Optimized conditions were used to produce samples for sensory evaluation. Color, spreadability, aroma, taste and general acceptability was evaluated using ranking difference test. The results showed that the yield, density, and iodine values of APOs oils ranged from 14.91 ± 0.18 to 11.76 ± 0.46;0.93 ± 0.001 to 0.99 ± 0.1;46.63 ± 1.70 to 52.4 ± 0.63, their acid values, TBA and PV values ranged from 1.42 ± 0.39 to 1.97 ± 0.5;0.11 ± 0.002 to 0.18 ± 0.04;and 2.72 ± 0.14 to 4.43 ± 0.36 respectively, with Brogdon avocado peel variety having the overall best properties prepared blends of trans-free APO margarines showed that increase in APO ratio decreased melting point, increased oxidative stability and reduced moisture content of margarine samples. Chitosan addition leads to decrease moisture content and increase functional properties. VCO lead to increase in phenolic and flavonoid content of the margarines. Samples were spreadable and palatable with R20 being most palatable and the most accepted being R26 with a mean score of 7.07 ± 0.70. Decrease in color intensity increased acceptability. This study therefore demonstrated that avocado peel waste biomass can be valorized by using it as raw material for oil extraction, which can serve as good material for the production of trans-free margarines with good oxidative stability, functional and antioxidant properties.
基金financially supported by the National Natural Science Foundation of China(No.52161016)Joint Key Project of Agricultural Fundamental Research in Yunnan Provinceg(No.202101BD070001-017)+3 种基金Yunnan Provincial Academician Workstation(No.202305AF150009)Yunnan Province Natural Science Key Foundation(No.202201AS070152)Special Project of“Top Young Talents”of Yunnan Ten Thousand Talents Plan(No.51900109)Special Project of"Leading Talents of Industrial Technology"of Yunnan Ten Thousand Talents Plan(No.80201408).
文摘The inhibitory properties of rapeseed cake meal extract(RCME)on the corrosion of cold rolled steel(CRS)in trichloroacetic acid(TCA)were systematically investigated using gravimetric,electrochemical,surface characterizations and theoretical calculations.The results demonstrate that RCME exhibits excellent inhibitory performance with a maximum inhibition efficiency of 92.7%for 100 mg L−1 RCME at 20℃.The adsorption of RCME obeys Langmuir isotherm at 20 and 30℃,Temkin isotherm at 40℃,and Freundlich isotherm at 50℃.RCME acts as a cathodic inhibitor.The charge transfer resistance is increased with the addition of RCME,while the double-layer capacitance decreases.SEM,AFM,CLSM,XPS,XRD and TOF-SIMS analyses confirm that the active components in RCME adsorb onto the surface of CRS,forming a protective film that effectively inhibits the corrosion of CRS by TCA.Along with the increase in the concentration of RCME,the surface tension of the inhibited solution gradually decreases,while the electrical conductivity increases before stabilizing.HPLC-MS and FTIR analyses reveal rutin,linolenic acid,linoleic acid and adenine are the effective substances in RCME.Quantum chemical(QC)calculations and molecular dynamic(MD)simulations indicate that the active centers of the effective inhibitor molecules are predominantly located on benzene rings,O-or N-containing heterocyclic rings,and functional groups such as C=O and C=C.Additionally,their main chains adsorb onto the Fe(001)surface in an approximately flat manner,involving both chemical and physical adsorption processes.
基金supported by the National Natural Science Foundation of Shandong(No.ZR2020ZD20)the National Natural Science Foundation of China(No.22193051)+1 种基金the National Young Top-Notch Talents(No.W03070030)the Youth Innovation Promotion Association of the Chinese Academy of Sciences(No.Y202011).
文摘Identification of the most appropriate chemically extractable pool for evaluating Cd and Pb availability remains elusive,hindering accurate assessment on environmental risks and effectiveness of remediation strategies.This study evaluated the feasibility of European Community Bureau of Reference(BCR)sequential extraction,Ca(NO_(3))_(2)extraction,and water extraction on assessing Cd and Pb availability in agricultural soil amended with slaked lime,magnesium hydroxide,corn stover biochar,and calcium dihydrogen phosphate.Moreover,the enriched isotope tracing technique(^(112)Cd and^(206)Pb)was employed to evaluate the aging process of newly introduced Cd and Pbwithin 56 days’incubation.Results demonstrated that extractable pools by BCR and Ca(NO_(3))_(2)extraction were little impacted by amendments and showed little correlation with soil pH.This is notable because soil pH is closely linked to metal availability,indicating these extraction methods may not adequately reflect metal availability.Conversely,water-soluble concentrations of Cd and Pb were markedly influenced by amendments and exhibited strong correlations with pH(Pearson’s r:-0.908 to-0.825,P<0.001),suggesting water extraction as a more sensitive approach.Furthermore,newly introduced metals underwent a more evident aging process as demonstrated by acid-soluble and water-soluble pools.Additionally,water-soluble concentrations of essential metals were impacted by soil amendments,raising caution on their potential effects on plant growth.These findings suggest water extraction as a promising and attractive method to evaluate Cd and Pb availability,which will help provide assessment guidance for environmental risks caused by heavy metals and develop efficient remediation strategies.
文摘BACKGROUND A total of 100 patients diagnosed with mixed hemorrhoids from October 2022 to September 2023 in our hospital were randomly divided into groups by dice rolling and compared with the efficacy of different treatment options.AIM To analyze the clinical effect and prognosis of mixed hemorrhoids treated with polidocanol injection combined with automatic elastic thread ligation operation(RPH).METHODS A total of 100 patients with mixed hemorrhoids who visited our hospital from October 2022 to September 2023 were selected and randomly divided into the control group(n=50)and the treatment group(n=50)by rolling the dice.The procedure for prolapse and hemorrhoids(PPH)was adopted in the control group,while polidocanol foam injection+RPH was adopted in the treatment group.The therapeutic effects,operation time,wound healing time,hospital stay,pain situation(24 hours post-operative pain score,first defecation pain score),quality of life(QOL),incidence of complications(post-operative hemorrhage,edema,infection),incidence of anal stenosis 3 months post-operatively and recurrence rate 1 year post-operatively of the two groups were compared.RESULTS Compared with the control group,the total effective rate of treatment group was higher,and the difference was significant(P<0.05).The operation time/wound healing time/hospital stay in the treatment group were shorter than those in the control group(P<0.05).The pain scores at 24 hours after operation/first defecation pain score of the treatment group was significantly lower than those in the control group(P<0.05).After surgery,the QOL scores of the two groups decreased,with the treatment group having higher scores than that of the control group(P<0.05).Compared with the control group,the incidence of postoperative complications in the treatment group was lower,and the difference was significant(P<0.05);However,there was no significant difference in the incidence of postoperative bleeding between the two groups(P>0.05);There was no significant difference in the incidence of anal stenosis 3 months after operation and the recurrence rate 1 year after operation between the two groups(P>0.05).CONCLUSION For patients with mixed hemorrhoids,the therapeutic effect achieved by using polidocanol injection combined with RPH was better.The wounds of the patients healed faster,the postoperative pain was milder,QOL improved,and the incidence of complications was lower,and the short-term and long-term prognosis was good.
基金Supported by National Natural Science Foundation of China(Grant Nos.51175422,61973011)Shaanxi Provincial Natural Science Basic Research Plan of China(Grant No.2022JM-195)+1 种基金Fundamental Research Funds for the Central Universities of Chinathe Research Start-up Funds of Hangzhou International Innovation Institute of Beihang University(Grant No.2024KQ036)。
文摘During high-speed rotation,the surface of aeronautic spiral bevel gears will generate significant pressure and viscous forces,which will cause a certain amount of windage power loss and reduce the efficiency of the transmission system.Based on the computational fluid dynamics,this paper analyzes the windage power loss of a single spiral bevel gear and a spiral bevel gear pair under oil injection lubrication.In addition,the shroud is used to suppress gear windage loss,and the clearance size and opening angle of the designed shroud are optimized.Finally,by comparing and analyzing the experimental results,the following conclusions were obtained:(1)For a single gear,the speed is the most important factor affecting windage loss,followed by the hand of spiral,and rotation direction;(2)For gear pairs,under oil injection lubrication,the input speed has the greatest impact on windage power loss,followed by the influence of oil injection port speed,temperature and oil injection port pressure;(3)Installing a shroud is an effective method to reduce windage power loss;(4)In the pure air phase,the smaller the clearance between the shroud and the gear surface,and the smaller the radial direction between the shroud and the shaft,the better the effect of reducing windage;(5)In the two-phase flow of oil and gas,it is necessary to design oil drainage holes on the shroud to ensure the smooth discharge of lubricating oil and improve the drag reduction effect.
基金supported by the Key Research and Development Program of Hunan Province of China(No.2022NK2036)Xiangxi Prefecture Science and Technology Plan Project"School-Local Integration"Special Project(No.2022001)the scientific research project of Hunan Provincial Department of Education(No.22B0520).
文摘Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in China.In vine tea processing,a large amount of broken tea is produced,which has low commercial value.Methods:This study investigates the influence of different extraction methods(room temperature water extraction,boiling water extraction,ultrasonic-assisted room temperature water extraction,and ultrasonic-assisted boiling water extraction,referred to as room temperature water extraction(RE),boiling water extraction(BE),ultrasonic assistance at room temperature water extraction(URE),and ultrasonic assistance in boiling water extraction(UBE))on the yield,dihydromyricetin(DMY)content,free amino acid composition,volatile aroma components,and antioxidant properties of vine tea extracts.Results:A notable influence of extraction temperature on the yield of vine tea extracts(P<0.05),with BE yielding the highest at 43.13±0.26%,higher than that of RE(34.29±0.81%).Ultrasound-assisted extraction significantly increased the DMY content of the extracts(P<0.05),whereas DMY content in the RE extracts was 59.94±1.70%,that of URE reached 66.14±2.78%.Analysis revealed 17 amino acids,with L-serine and aspartic acid being the most abundant in the extracts,nevertheless ultrasound-assisted extraction reduced total free amino acid content.Gas chromatography-mass spectrometry analysis demonstrated an increase in the diversity and quantity of compounds in the vine tea water extracts obtained through ultrasonic-assisted extraction.Specifically,69 and 68 volatile compounds were found in URE and UBE extracts,which were higher than the number found in RE and BE extracts.In vitro,antioxidant activity assessments revealed varying antioxidant capacities among different extraction methods,with RE exhibiting the highest DPPH scavenging rate,URE leading in ABTS•+free radical scavenging,and BE demonstrating superior ferric ion reducing antioxidant activity.Conclusion:The findings suggest that extraction methods significantly influence the chemical composition and antioxidant properties of vine tea extracts.Ultrasonic-assisted extraction proved instrumental in elevating the DMY content in vine tea extracts,thereby enriching its flavor profile while maintaining its antioxidant properties.
