Against the backdrop of the rapid intelligent development of medical laboratory technology,vocational education is in urgent need of teaching innovation.This paper explores the integration and practice of information-...Against the backdrop of the rapid intelligent development of medical laboratory technology,vocational education is in urgent need of teaching innovation.This paper explores the integration and practice of information-based teaching methods in vocational education of medical laboratory technology,analyzes the current situation of traditional teaching and the demand for informatization,and elaborates on the practical paths from aspects such as resource construction,model innovation,and evaluation reform.Practice has verified that this integration has improved teaching quality and students’skills,but there are problems such as uneven resources and the need to improve teachers’and students’abilities.Countermeasures such as strengthening co-construction and sharing of resources and carrying out special training are proposed to provide reference for the development of professional education.展开更多
Objective:To explore the application effect of an information-based flipped classroom teaching model in nursing education of rheumatology and immunology,providing empirical evidence for optimizing specialized nursing ...Objective:To explore the application effect of an information-based flipped classroom teaching model in nursing education of rheumatology and immunology,providing empirical evidence for optimizing specialized nursing education models.Methods:Eighty nursing students from the 2021 grade of Xi’an Medical University were selected as research subjects and randomly divided into an experimental group(n=40)and a control group(n=40)using a random number table method.The control group received traditional lecture-based teaching,while the experimental group underwent information-based flipped classroom teaching.The theoretical knowledge scores and practical operation assessment scores of the two groups were compared after teaching,and the teaching satisfaction of the experimental group students was evaluated through a questionnaire survey.Results:The theoretical knowledge score(85.60±5.20)and practical operation score(88.30±4.70)of the experimental group were significantly higher than those of the control group(76.20±6.50)and(75.80±5.90),respectively.The differences were statistically significant(p<0.05).The satisfaction scores of all dimensions in the experimental group were significantly higher than those in the control group,and the differences were statistically significant(p<0.05).Conclusion:The information-based flipped classroom teaching model can effectively improve the quality of nursing teaching in rheumatology and immunology,enhance students’knowledge mastery and practical abilities,and is worthy of promotion and application in clinical nursing teaching.展开更多
We extend the information-based asset-pricing framework by Brody,Hughston&Macrina to incorporate a stochastic bankruptcy time for the writer of the asset.Our model introduces a non-defaultable cash flow Zr to be m...We extend the information-based asset-pricing framework by Brody,Hughston&Macrina to incorporate a stochastic bankruptcy time for the writer of the asset.Our model introduces a non-defaultable cash flow Zr to be made at time T,alongside the time T of a possible bankruptcy of the writer of the asset are in line with the filtration generated by a Brownian random bridge with length v=T^T and pinning point ZT,where is a constant.Quantities Z and T are not necessarily independent.The model does not depend crucially on the interpretation of as a bankruptcy time.We derived the price process of the asset and compute the prices of associated options.The dynamics of the price process satisfy a diffusion equation.Employing the approach of P.-A.Meyer,we provide the explicit computation of the compensator of v.Leveraging special properties of the bridge process,we also provide the explicit expression of the compensator of Zr I(v,+o).The resulting conclusion highlights the totally inaccessible property of the stopping time v.This characteristic is particularly suitable for financial markets where the time of default of a writer cannot be predictable from any other signal in the system until default happens.展开更多
BACKGROUND Due to the increasing rate of thyroid nodules diagnosis,and the desire to avoid the unsightly cervical scar,remote thyroidectomies were invented and are increasingly performed.Transoral endoscopic thyroidec...BACKGROUND Due to the increasing rate of thyroid nodules diagnosis,and the desire to avoid the unsightly cervical scar,remote thyroidectomies were invented and are increasingly performed.Transoral endoscopic thyroidectomy vestibular approach and trans-areolar approaches(TAA)are the two most commonly used remote approaches.No previous meta-analysis has compared postoperative infections and swallowing difficulties among the two procedures.AIM To compared the same among patients undergoing lobectomy for unilateral thyroid carcinoma/benign thyroid nodule.METHODS We searched PubMed MEDLINE,Google Scholar,and Cochrane Library from the date of the first published article up to August 2025.The term used were transoral thyroidectomy vestibular approach,trans areolar thyroidectomy,scarless thyroidectomy,remote thyroidectomy,infections,postoperative,inflammation,dysphagia,and swallowing difficulties.We identified 130 studies,of them,30 full texts were screened and only six studies were included in the final meta-analysis.RESULTS Postoperative infections were not different between the two approaches,odd ratio=1.33,95%confidence interval:0.50-3.53,theχ2 was 1.92 and the P-value for overall effect of 0.57.Similarly,transient swallowing difficulty was not different between the two forms of surgery,with odd ratio=0.91,95%confidence interval:0.35-2.40;theχ2 was 1.32,and the P-value for overall effect of 0.85.CONCLUSION No significant statistical differences were evident between trans-oral endoscopic Mirghani H.Infections and swallowing difficulty in scarless thyroidectomy WJCC https://www.wjgnet.com 2 January 6,2026 Volume 14 Issue 1 thyroidectomy vestibular approach and trans-areolar approach regarding postoperative infection and transient swallowing difficulties.Further longer randomized trials are needed.展开更多
In the context of educational informatization reform,there are many uncertain factors in the process of education development.To optimize the educational environment so that it can be effectively combined with informa...In the context of educational informatization reform,there are many uncertain factors in the process of education development.To optimize the educational environment so that it can be effectively combined with information technology,teachers need to change their teaching ideas,strengthen the school’s own adaptability to informatization,and promote the development of informatization construction in schools.As a branch of information leadership,the management team should establish an evaluation index system for information leadership in order to ensure the construction of school informatization,so as to provide a boost for the integration of school resources and information technology.Based on the overview and connotation of information-based leadership of the management team,this paper explores the construction of an evaluation index system of information-based leadership of the school management team,aiming to provide references for the research of relevant personnel in the future.展开更多
The photoacoustic imaging of lipid is intrinsically constrained by the feeble nature of endogenous lipid signals,posing a persistent sensitivity challenge that demands innovative solutions.Although adopting high-effic...The photoacoustic imaging of lipid is intrinsically constrained by the feeble nature of endogenous lipid signals,posing a persistent sensitivity challenge that demands innovative solutions.Although adopting high-efficiency excitation and detection elements may improve the imaging sensitivity to a certain extent,the application of the elements is inevitably subject to various limitations in practical applications,particularly during in vivo imaging and endoscopic imaging.In this study,we propose a multi-combinatorial approach to enhance the sensitivity of lipid photoacoustic imaging.The approach involves wavelet transform processing of one-dimensional A-line signals,gradient-based denoising of two-dimensional B-scan images,and finally,threedimensional spatial weighted averaging of the data processed by the previous two steps.This method not only significantly improves the signal-to-noise ratio(SNR)in distinguished feature regions of the image by around 10 dB,but also efficiently extracts weak signals with no distinct features in the original image.After processing with this method,the images acquired under single scanning were compared with those obtained under multiple scanning.The results showed highly consistent image features,with the structural similarity index increasing from 0.2 to 0.8,confirming the accuracy and reliability of the multi-combinatorial approach.展开更多
The 17 Sustainable Development Goals(SDGs)for 2030,adopted by all United Nations member states in 2015,are facing a range of challenges.Factors such as climate change,regional conflicts and economic recession are havi...The 17 Sustainable Development Goals(SDGs)for 2030,adopted by all United Nations member states in 2015,are facing a range of challenges.Factors such as climate change,regional conflicts and economic recession are having a significant impact,particularly on global poverty governance.As a platform for dialogue,exchange and technical cooperation,the 2025 International Seminar on Global Poverty Reduction Partnerships was held in Beijing on 10 December 2025.展开更多
On the basis of expounding connotation and significance of expansion of agricultural industrial chain,coupled with the connotation of rural informatization connotation,this article analyses the role of rural informati...On the basis of expounding connotation and significance of expansion of agricultural industrial chain,coupled with the connotation of rural informatization connotation,this article analyses the role of rural informatization in expanding agricultural industrial chain:it can enhance market competitiveness of industry chain,improve the operational efficiency of industry chain,and promote the income and quality of farmers in industry chain.Under the perspective of expanding agricultural industrial chain,this article puts forwards thinking about the construction of rural informatization as follows:first,give full play to the leading role of the government;second,strengthen the construction of information-based network facility;third,integrate information resources in rural areas,and improve the quality of information;fourth,build comprehensive information service platform in rural areas;fifth,improve organizational level of production and management of individual farmers;sixth,strengthen the construction of information-based personnel in rural areas;seventh,strengthen publicity and training,promote overall cultural quality and information awareness of farmers.展开更多
Taking the knowledge points of hotel construction site selection as an example,this paper integrated the information-based teaching method with traditional classrooms.With the aid of virtual reality(VR)technology,the ...Taking the knowledge points of hotel construction site selection as an example,this paper integrated the information-based teaching method with traditional classrooms.With the aid of virtual reality(VR)technology,the information-based teaching can turn the abstract knowledge into vivid knowledge.Using the Rain Classroom platform,teachers can communicate with students in a better manner.Combined with the powerful spatial data analysis function of geographic information system(GIS)software,it is intended to provide new ideas and perspectives for the effective integration of traditional teaching classrooms and information technology,and effectively apply them to the practical teaching process.展开更多
The Bermudan option pricing problem with variable transaction costs is considered for a risky asset whose price process is derived under the information-based model. The price is formulated as the value function of an...The Bermudan option pricing problem with variable transaction costs is considered for a risky asset whose price process is derived under the information-based model. The price is formulated as the value function of an optimal stopping problem, which is the value function of a stochastic control problem given by a non-linear second order partial differential equation. The theory of viscosity solutions is applied to solve the stochastic control problem such that the value function is also the solution of the corresponding Bellman equation. Under some regularity assumptions, the existence and uniqueness of the solution of the pricing equation are derived by the application of the Perron method and Banach Fixed Point theorem.展开更多
The innovation of enterprise management model and the improvement of efficiency are the impetuses to the internal development of enterprises. Computer information technology, with its advantages in low cost, high effi...The innovation of enterprise management model and the improvement of efficiency are the impetuses to the internal development of enterprises. Computer information technology, with its advantages in low cost, high efficiency and high quality, has been widely popularized and applied in the enterprise development. In this paper, the core competitiveness of enterprises in the information age and the far-reaching influence of a creative, sustainable growth on the development of enterprises are analyzed mainly from the information-based application in enterprise management and the influence of informatization and networking on enterprise management.展开更多
This paper deals with the parallel information-based complexity of numerical integration on Sobolev class. We obtain tight bounds on the complexity, considered as a function of two variables simultaneously:the number ...This paper deals with the parallel information-based complexity of numerical integration on Sobolev class. We obtain tight bounds on the complexity, considered as a function of two variables simultaneously:the number of processors, the rquired precision. This result seems to be new even in serial case.展开更多
The so-called evaluation index system refers to the establishment of an evaluation system based on the main characteristics of each aspect of the evaluation object and the related parameter indexes. In the process of ...The so-called evaluation index system refers to the establishment of an evaluation system based on the main characteristics of each aspect of the evaluation object and the related parameter indexes. In the process of higher vocational education, with the combination of online and offline education and the continuous expansion of online course resources, many online courses have achieved resource sharing. How to effectively integrate teaching resources and give full play to the main advantages of teaching resources has become the focus of higher vocational education. This paper focuses on the information-based teaching model of higher vocational education, and analyzes the integration of teaching resources and the evaluation content for reference only.展开更多
With the worldwide research and development of digital information technology, the world has entered the information age. All walks of life have undergone tremendous changes under the blessing of information technolog...With the worldwide research and development of digital information technology, the world has entered the information age. All walks of life have undergone tremendous changes under the blessing of information technology. Education is no exception. In an era when information technology is so developed, secondary vocational teachers need to keep up with the pace of the times and integrate information technology and music teaching, which can make the classroom full of interest, make teaching more intuitive and efficient, and improve students' enthusiasm to participate in teaching, so as to better promote the smooth achievement of teaching objectives. This paper mainly focuses on the music classroom of secondary vocational schools in China. While analyzing the role of music in secondary vocational schools, it discusses the significance and current situation of the integration of information-based teaching and music classroom of secondary vocational schools, and finally focuses on how to further integrate information-based teaching in music classroom of secondary vocational schools.展开更多
Cardiovascular diseases(CVDs)remain the leading cause of morbidity and mortality worldwide,necessitating innovative diagnostic and prognostic strategies.Traditional biomarkers like C-reactive protein,uric acid,troponi...Cardiovascular diseases(CVDs)remain the leading cause of morbidity and mortality worldwide,necessitating innovative diagnostic and prognostic strategies.Traditional biomarkers like C-reactive protein,uric acid,troponin,and natriuretic peptides play crucial roles in CVD management,yet they are often limited by sensitivity and specificity constraints.This narrative review critically examines the emerging landscape of cardiac biomarkers and advocates for a multiple-marker approach to enhance early detection,prognosis,and risk stratification of CVD.In recent years,several novel biomarkers have shown promise in revolutionizing CVD diagnostics.Gamma-glutamyltransferase,microRNAs,endothelial microparticles,placental growth factor,trimethylamine N-oxide,retinol-binding protein 4,copeptin,heart-type fatty acid-binding protein,galectin-3,growth differentiation factor-15,soluble suppression of tumorigenicity 2,fibroblast growth factor 23,and adrenomedullin have emerged as significant indicators of CV health.These biomarkers provide insights into various pathophysiological processes,such as oxidative stress,endothelial dysfunction,inflammation,metabolic disturbances,and myocardial injury.The integration of these novel biomarkers with traditional ones offers a more comprehensive understanding of CVD mechanisms.This multiple-marker approach can improve diagnostic accuracy,allowing for better risk stratification and more personalized treatment strategies.This review underscores the need for continued research to validate the clinical utility of these biomarkers and their potential incorporation into routine clinical practice.By leveraging the strengths of both traditional and novel biomarkers,precise therapeutic plans can be developed,thereby improving the management and prognosis of patients with CVDs.The ongoing exploration and validation of these biomarkers are crucial for advancing CV care and addressing the limitations of current diagnostic tools.展开更多
Under the influence of the information technology revolution,the teaching method,as the way to impart teaching content or the means to realize teaching content,has undergone a process of constant evolution and transfo...Under the influence of the information technology revolution,the teaching method,as the way to impart teaching content or the means to realize teaching content,has undergone a process of constant evolution and transformation.This transformation is still ongoing.In order to explain this phenomenon,we establish a three-dimension analysis framework of"ECONOMIC BASE-INFORMATION TECHNOLOGY-CULTURE".All kinds of logics involved in them are closely linked,thus influencing each other.At the same time,these aspects constantly affect the historical trajectory of the evolution.Based on the above analysis framework,the paper uses the historical approach to expound the evolution path on teaching methods in China since ancient times and divides it into four stages.Combined with the practical problems and interview results,we rethink the present information teaching methods.In the end,some suggestions are put forward in order to promote the further development of education-related fields.展开更多
For large-scale heterogeneous multi-agent systems(MASs)with characteristics of dense-sparse mixed distribution,this paper investigates the practical finite-time deployment problem by establishing a novel crossspecies ...For large-scale heterogeneous multi-agent systems(MASs)with characteristics of dense-sparse mixed distribution,this paper investigates the practical finite-time deployment problem by establishing a novel crossspecies bionic analytical framework based on the partial differential equation-ordinary differential equation(PDE-ODE)approach.Specifically,by designing a specialized network communication protocol and employing the spatial continuum method for densely distributed agents,this paper models the tracking errors of densely distributed agents as a PDE equivalent to a human disease transmission model,and that of sparsely distributed agents as several ODEs equivalent to the predator population models.The coupling relationship between the PDE and ODE models is established through boundary conditions of the PDE,thereby forming a PDE-ODE-based tracking error model for the considered MASs.Furthermore,by integrating adaptive neural control scheme with the aforementioned biological models,a“Flexible Neural Network”endowed with adaptive and self-stabilized capabilities is constructed,which acts upon the considered MASs,enabling their practical finite-time deployment.Finally,effectiveness of the developed approach is illustrated through a numerical example.展开更多
The progressive loss of dopaminergic neurons in affected patient brains is one of the pathological features of Parkinson's disease,the second most common human neurodegenerative disease.Although the detailed patho...The progressive loss of dopaminergic neurons in affected patient brains is one of the pathological features of Parkinson's disease,the second most common human neurodegenerative disease.Although the detailed pathogenesis accounting for dopaminergic neuron degeneration in Parkinson's disease is still unclear,the advancement of stem cell approaches has shown promise for Parkinson's disease research and therapy.The induced pluripotent stem cells have been commonly used to generate dopaminergic neurons,which has provided valuable insights to improve our understanding of Parkinson's disease pathogenesis and contributed to anti-Parkinson's disease therapies.The current review discusses the practical approaches and potential applications of induced pluripotent stem cell techniques for generating and differentiating dopaminergic neurons from induced pluripotent stem cells.The benefits of induced pluripotent stem cell-based research are highlighted.Various dopaminergic neuron differentiation protocols from induced pluripotent stem cells are compared.The emerging three-dimension-based brain organoid models compared with conventional two-dimensional cell culture are evaluated.Finally,limitations,challenges,and future directions of induced pluripotent stem cell–based approaches are analyzed and proposed,which will be significant to the future application of induced pluripotent stem cell-related techniques for Parkinson's disease.展开更多
Deep learning algorithms have been rapidly incorporated into many different applications due to the increase in computational power and the availability of massive amounts of data.Recently,both deep learning and ensem...Deep learning algorithms have been rapidly incorporated into many different applications due to the increase in computational power and the availability of massive amounts of data.Recently,both deep learning and ensemble learning have been used to recognize underlying structures and patterns from high-level features to make predictions/decisions.With the growth in popularity of deep learning and ensemble learning algorithms,they have received significant attention from both scientists and the industrial community due to their superior ability to learn features from big data.Ensemble deep learning has exhibited significant performance in enhancing learning generalization through the use of multiple deep learning algorithms.Although ensemble deep learning has large quantities of training parameters,which results in time and space overheads,it performs much better than traditional ensemble learning.Ensemble deep learning has been successfully used in several areas,such as bioinformatics,finance,and health care.In this paper,we review and investigate recent ensemble deep learning algorithms and techniques in health care domains,medical imaging,health care data analytics,genomics,diagnosis,disease prevention,and drug discovery.We cover several widely used deep learning algorithms along with their architectures,including deep neural networks(DNNs),convolutional neural networks(CNNs),recurrent neural networks(RNNs),and generative adversarial networks(GANs).Common healthcare tasks,such as medical imaging,electronic health records,and genomics,are also demonstrated.Furthermore,in this review,the challenges inherent in reducing the burden on the healthcare system are discussed and explored.Finally,future directions and opportunities for enhancing healthcare model performance are discussed.展开更多
文摘Against the backdrop of the rapid intelligent development of medical laboratory technology,vocational education is in urgent need of teaching innovation.This paper explores the integration and practice of information-based teaching methods in vocational education of medical laboratory technology,analyzes the current situation of traditional teaching and the demand for informatization,and elaborates on the practical paths from aspects such as resource construction,model innovation,and evaluation reform.Practice has verified that this integration has improved teaching quality and students’skills,but there are problems such as uneven resources and the need to improve teachers’and students’abilities.Countermeasures such as strengthening co-construction and sharing of resources and carrying out special training are proposed to provide reference for the development of professional education.
文摘Objective:To explore the application effect of an information-based flipped classroom teaching model in nursing education of rheumatology and immunology,providing empirical evidence for optimizing specialized nursing education models.Methods:Eighty nursing students from the 2021 grade of Xi’an Medical University were selected as research subjects and randomly divided into an experimental group(n=40)and a control group(n=40)using a random number table method.The control group received traditional lecture-based teaching,while the experimental group underwent information-based flipped classroom teaching.The theoretical knowledge scores and practical operation assessment scores of the two groups were compared after teaching,and the teaching satisfaction of the experimental group students was evaluated through a questionnaire survey.Results:The theoretical knowledge score(85.60±5.20)and practical operation score(88.30±4.70)of the experimental group were significantly higher than those of the control group(76.20±6.50)and(75.80±5.90),respectively.The differences were statistically significant(p<0.05).The satisfaction scores of all dimensions in the experimental group were significantly higher than those in the control group,and the differences were statistically significant(p<0.05).Conclusion:The information-based flipped classroom teaching model can effectively improve the quality of nursing teaching in rheumatology and immunology,enhance students’knowledge mastery and practical abilities,and is worthy of promotion and application in clinical nursing teaching.
文摘We extend the information-based asset-pricing framework by Brody,Hughston&Macrina to incorporate a stochastic bankruptcy time for the writer of the asset.Our model introduces a non-defaultable cash flow Zr to be made at time T,alongside the time T of a possible bankruptcy of the writer of the asset are in line with the filtration generated by a Brownian random bridge with length v=T^T and pinning point ZT,where is a constant.Quantities Z and T are not necessarily independent.The model does not depend crucially on the interpretation of as a bankruptcy time.We derived the price process of the asset and compute the prices of associated options.The dynamics of the price process satisfy a diffusion equation.Employing the approach of P.-A.Meyer,we provide the explicit computation of the compensator of v.Leveraging special properties of the bridge process,we also provide the explicit expression of the compensator of Zr I(v,+o).The resulting conclusion highlights the totally inaccessible property of the stopping time v.This characteristic is particularly suitable for financial markets where the time of default of a writer cannot be predictable from any other signal in the system until default happens.
文摘BACKGROUND Due to the increasing rate of thyroid nodules diagnosis,and the desire to avoid the unsightly cervical scar,remote thyroidectomies were invented and are increasingly performed.Transoral endoscopic thyroidectomy vestibular approach and trans-areolar approaches(TAA)are the two most commonly used remote approaches.No previous meta-analysis has compared postoperative infections and swallowing difficulties among the two procedures.AIM To compared the same among patients undergoing lobectomy for unilateral thyroid carcinoma/benign thyroid nodule.METHODS We searched PubMed MEDLINE,Google Scholar,and Cochrane Library from the date of the first published article up to August 2025.The term used were transoral thyroidectomy vestibular approach,trans areolar thyroidectomy,scarless thyroidectomy,remote thyroidectomy,infections,postoperative,inflammation,dysphagia,and swallowing difficulties.We identified 130 studies,of them,30 full texts were screened and only six studies were included in the final meta-analysis.RESULTS Postoperative infections were not different between the two approaches,odd ratio=1.33,95%confidence interval:0.50-3.53,theχ2 was 1.92 and the P-value for overall effect of 0.57.Similarly,transient swallowing difficulty was not different between the two forms of surgery,with odd ratio=0.91,95%confidence interval:0.35-2.40;theχ2 was 1.32,and the P-value for overall effect of 0.85.CONCLUSION No significant statistical differences were evident between trans-oral endoscopic Mirghani H.Infections and swallowing difficulty in scarless thyroidectomy WJCC https://www.wjgnet.com 2 January 6,2026 Volume 14 Issue 1 thyroidectomy vestibular approach and trans-areolar approach regarding postoperative infection and transient swallowing difficulties.Further longer randomized trials are needed.
文摘In the context of educational informatization reform,there are many uncertain factors in the process of education development.To optimize the educational environment so that it can be effectively combined with information technology,teachers need to change their teaching ideas,strengthen the school’s own adaptability to informatization,and promote the development of informatization construction in schools.As a branch of information leadership,the management team should establish an evaluation index system for information leadership in order to ensure the construction of school informatization,so as to provide a boost for the integration of school resources and information technology.Based on the overview and connotation of information-based leadership of the management team,this paper explores the construction of an evaluation index system of information-based leadership of the school management team,aiming to provide references for the research of relevant personnel in the future.
基金supported by the National Key Research and Development Program of China(2022YFC2402400)the National Natural Science Foundation of China(82027803,62275062)+7 种基金the Guangdong Provincial Key Laboratory of Biomedical Optical Imaging Technology(2020B121201010)the Shenzhen Science and Technology Innovation Committee under Grant(JCYJ20220818101417039)the Shenzhen Key Laboratory for Molecular lmaging(ZDSY20130401165820357)the Shenzhen Medical Research Fund(D2404002)the Project of Shandong Innovation and Startup Community of High-end Medical Apparatus and Instruments(2023-SGTTXM-002 and 2024-SGTTXM-005)the Shandong Province Technology Innovation Guidance Plan(Central Leading Local Science and Technology Development Fund)(YDZX2023115)the Taishan Scholar Special Funding Project of Shandong Provinceand the Shandong Laboratory of Advanced Biomaterials and Medical Devices in Weihai(ZL202402).
文摘The photoacoustic imaging of lipid is intrinsically constrained by the feeble nature of endogenous lipid signals,posing a persistent sensitivity challenge that demands innovative solutions.Although adopting high-efficiency excitation and detection elements may improve the imaging sensitivity to a certain extent,the application of the elements is inevitably subject to various limitations in practical applications,particularly during in vivo imaging and endoscopic imaging.In this study,we propose a multi-combinatorial approach to enhance the sensitivity of lipid photoacoustic imaging.The approach involves wavelet transform processing of one-dimensional A-line signals,gradient-based denoising of two-dimensional B-scan images,and finally,threedimensional spatial weighted averaging of the data processed by the previous two steps.This method not only significantly improves the signal-to-noise ratio(SNR)in distinguished feature regions of the image by around 10 dB,but also efficiently extracts weak signals with no distinct features in the original image.After processing with this method,the images acquired under single scanning were compared with those obtained under multiple scanning.The results showed highly consistent image features,with the structural similarity index increasing from 0.2 to 0.8,confirming the accuracy and reliability of the multi-combinatorial approach.
文摘The 17 Sustainable Development Goals(SDGs)for 2030,adopted by all United Nations member states in 2015,are facing a range of challenges.Factors such as climate change,regional conflicts and economic recession are having a significant impact,particularly on global poverty governance.As a platform for dialogue,exchange and technical cooperation,the 2025 International Seminar on Global Poverty Reduction Partnerships was held in Beijing on 10 December 2025.
文摘On the basis of expounding connotation and significance of expansion of agricultural industrial chain,coupled with the connotation of rural informatization connotation,this article analyses the role of rural informatization in expanding agricultural industrial chain:it can enhance market competitiveness of industry chain,improve the operational efficiency of industry chain,and promote the income and quality of farmers in industry chain.Under the perspective of expanding agricultural industrial chain,this article puts forwards thinking about the construction of rural informatization as follows:first,give full play to the leading role of the government;second,strengthen the construction of information-based network facility;third,integrate information resources in rural areas,and improve the quality of information;fourth,build comprehensive information service platform in rural areas;fifth,improve organizational level of production and management of individual farmers;sixth,strengthen the construction of information-based personnel in rural areas;seventh,strengthen publicity and training,promote overall cultural quality and information awareness of farmers.
文摘Taking the knowledge points of hotel construction site selection as an example,this paper integrated the information-based teaching method with traditional classrooms.With the aid of virtual reality(VR)technology,the information-based teaching can turn the abstract knowledge into vivid knowledge.Using the Rain Classroom platform,teachers can communicate with students in a better manner.Combined with the powerful spatial data analysis function of geographic information system(GIS)software,it is intended to provide new ideas and perspectives for the effective integration of traditional teaching classrooms and information technology,and effectively apply them to the practical teaching process.
文摘The Bermudan option pricing problem with variable transaction costs is considered for a risky asset whose price process is derived under the information-based model. The price is formulated as the value function of an optimal stopping problem, which is the value function of a stochastic control problem given by a non-linear second order partial differential equation. The theory of viscosity solutions is applied to solve the stochastic control problem such that the value function is also the solution of the corresponding Bellman equation. Under some regularity assumptions, the existence and uniqueness of the solution of the pricing equation are derived by the application of the Perron method and Banach Fixed Point theorem.
文摘The innovation of enterprise management model and the improvement of efficiency are the impetuses to the internal development of enterprises. Computer information technology, with its advantages in low cost, high efficiency and high quality, has been widely popularized and applied in the enterprise development. In this paper, the core competitiveness of enterprises in the information age and the far-reaching influence of a creative, sustainable growth on the development of enterprises are analyzed mainly from the information-based application in enterprise management and the influence of informatization and networking on enterprise management.
基金this work was supported by china State Major Key Project for Basic Researchers
文摘This paper deals with the parallel information-based complexity of numerical integration on Sobolev class. We obtain tight bounds on the complexity, considered as a function of two variables simultaneously:the number of processors, the rquired precision. This result seems to be new even in serial case.
文摘The so-called evaluation index system refers to the establishment of an evaluation system based on the main characteristics of each aspect of the evaluation object and the related parameter indexes. In the process of higher vocational education, with the combination of online and offline education and the continuous expansion of online course resources, many online courses have achieved resource sharing. How to effectively integrate teaching resources and give full play to the main advantages of teaching resources has become the focus of higher vocational education. This paper focuses on the information-based teaching model of higher vocational education, and analyzes the integration of teaching resources and the evaluation content for reference only.
文摘With the worldwide research and development of digital information technology, the world has entered the information age. All walks of life have undergone tremendous changes under the blessing of information technology. Education is no exception. In an era when information technology is so developed, secondary vocational teachers need to keep up with the pace of the times and integrate information technology and music teaching, which can make the classroom full of interest, make teaching more intuitive and efficient, and improve students' enthusiasm to participate in teaching, so as to better promote the smooth achievement of teaching objectives. This paper mainly focuses on the music classroom of secondary vocational schools in China. While analyzing the role of music in secondary vocational schools, it discusses the significance and current situation of the integration of information-based teaching and music classroom of secondary vocational schools, and finally focuses on how to further integrate information-based teaching in music classroom of secondary vocational schools.
文摘Cardiovascular diseases(CVDs)remain the leading cause of morbidity and mortality worldwide,necessitating innovative diagnostic and prognostic strategies.Traditional biomarkers like C-reactive protein,uric acid,troponin,and natriuretic peptides play crucial roles in CVD management,yet they are often limited by sensitivity and specificity constraints.This narrative review critically examines the emerging landscape of cardiac biomarkers and advocates for a multiple-marker approach to enhance early detection,prognosis,and risk stratification of CVD.In recent years,several novel biomarkers have shown promise in revolutionizing CVD diagnostics.Gamma-glutamyltransferase,microRNAs,endothelial microparticles,placental growth factor,trimethylamine N-oxide,retinol-binding protein 4,copeptin,heart-type fatty acid-binding protein,galectin-3,growth differentiation factor-15,soluble suppression of tumorigenicity 2,fibroblast growth factor 23,and adrenomedullin have emerged as significant indicators of CV health.These biomarkers provide insights into various pathophysiological processes,such as oxidative stress,endothelial dysfunction,inflammation,metabolic disturbances,and myocardial injury.The integration of these novel biomarkers with traditional ones offers a more comprehensive understanding of CVD mechanisms.This multiple-marker approach can improve diagnostic accuracy,allowing for better risk stratification and more personalized treatment strategies.This review underscores the need for continued research to validate the clinical utility of these biomarkers and their potential incorporation into routine clinical practice.By leveraging the strengths of both traditional and novel biomarkers,precise therapeutic plans can be developed,thereby improving the management and prognosis of patients with CVDs.The ongoing exploration and validation of these biomarkers are crucial for advancing CV care and addressing the limitations of current diagnostic tools.
文摘Under the influence of the information technology revolution,the teaching method,as the way to impart teaching content or the means to realize teaching content,has undergone a process of constant evolution and transformation.This transformation is still ongoing.In order to explain this phenomenon,we establish a three-dimension analysis framework of"ECONOMIC BASE-INFORMATION TECHNOLOGY-CULTURE".All kinds of logics involved in them are closely linked,thus influencing each other.At the same time,these aspects constantly affect the historical trajectory of the evolution.Based on the above analysis framework,the paper uses the historical approach to expound the evolution path on teaching methods in China since ancient times and divides it into four stages.Combined with the practical problems and interview results,we rethink the present information teaching methods.In the end,some suggestions are put forward in order to promote the further development of education-related fields.
基金The National Key R&D Program of China(2021ZD0201300)the National Natural Science Foundation of China(624B2058,U1913602 and 61936004)+1 种基金the Innovation Group Project of the National Natural Science Foundation of China(61821003)the 111 Project on Computational Intelligence and Intelligent Control(B18024).
文摘For large-scale heterogeneous multi-agent systems(MASs)with characteristics of dense-sparse mixed distribution,this paper investigates the practical finite-time deployment problem by establishing a novel crossspecies bionic analytical framework based on the partial differential equation-ordinary differential equation(PDE-ODE)approach.Specifically,by designing a specialized network communication protocol and employing the spatial continuum method for densely distributed agents,this paper models the tracking errors of densely distributed agents as a PDE equivalent to a human disease transmission model,and that of sparsely distributed agents as several ODEs equivalent to the predator population models.The coupling relationship between the PDE and ODE models is established through boundary conditions of the PDE,thereby forming a PDE-ODE-based tracking error model for the considered MASs.Furthermore,by integrating adaptive neural control scheme with the aforementioned biological models,a“Flexible Neural Network”endowed with adaptive and self-stabilized capabilities is constructed,which acts upon the considered MASs,enabling their practical finite-time deployment.Finally,effectiveness of the developed approach is illustrated through a numerical example.
基金supported by Singapore National Medical Research Council(NMRC)grants,including CS-IRG,HLCA2022(to ZDZ),STaR,OF LCG 000207(to EKT)a Clinical Translational Research Programme in Parkinson's DiseaseDuke-Duke-NUS collaboration pilot grant(to ZDZ)。
文摘The progressive loss of dopaminergic neurons in affected patient brains is one of the pathological features of Parkinson's disease,the second most common human neurodegenerative disease.Although the detailed pathogenesis accounting for dopaminergic neuron degeneration in Parkinson's disease is still unclear,the advancement of stem cell approaches has shown promise for Parkinson's disease research and therapy.The induced pluripotent stem cells have been commonly used to generate dopaminergic neurons,which has provided valuable insights to improve our understanding of Parkinson's disease pathogenesis and contributed to anti-Parkinson's disease therapies.The current review discusses the practical approaches and potential applications of induced pluripotent stem cell techniques for generating and differentiating dopaminergic neurons from induced pluripotent stem cells.The benefits of induced pluripotent stem cell-based research are highlighted.Various dopaminergic neuron differentiation protocols from induced pluripotent stem cells are compared.The emerging three-dimension-based brain organoid models compared with conventional two-dimensional cell culture are evaluated.Finally,limitations,challenges,and future directions of induced pluripotent stem cell–based approaches are analyzed and proposed,which will be significant to the future application of induced pluripotent stem cell-related techniques for Parkinson's disease.
基金funded by Taif University,Saudi Arabia,project No.(TU-DSPP-2024-263).
文摘Deep learning algorithms have been rapidly incorporated into many different applications due to the increase in computational power and the availability of massive amounts of data.Recently,both deep learning and ensemble learning have been used to recognize underlying structures and patterns from high-level features to make predictions/decisions.With the growth in popularity of deep learning and ensemble learning algorithms,they have received significant attention from both scientists and the industrial community due to their superior ability to learn features from big data.Ensemble deep learning has exhibited significant performance in enhancing learning generalization through the use of multiple deep learning algorithms.Although ensemble deep learning has large quantities of training parameters,which results in time and space overheads,it performs much better than traditional ensemble learning.Ensemble deep learning has been successfully used in several areas,such as bioinformatics,finance,and health care.In this paper,we review and investigate recent ensemble deep learning algorithms and techniques in health care domains,medical imaging,health care data analytics,genomics,diagnosis,disease prevention,and drug discovery.We cover several widely used deep learning algorithms along with their architectures,including deep neural networks(DNNs),convolutional neural networks(CNNs),recurrent neural networks(RNNs),and generative adversarial networks(GANs).Common healthcare tasks,such as medical imaging,electronic health records,and genomics,are also demonstrated.Furthermore,in this review,the challenges inherent in reducing the burden on the healthcare system are discussed and explored.Finally,future directions and opportunities for enhancing healthcare model performance are discussed.
