To the Editor:Klebsiella pneumoniae(KP)is a common opportunistic pathogen causing potentially life-threatening illness and organ failure.Surveillance data from the 2023 China Antimicrobial Surveillance Network(CHINET)...To the Editor:Klebsiella pneumoniae(KP)is a common opportunistic pathogen causing potentially life-threatening illness and organ failure.Surveillance data from the 2023 China Antimicrobial Surveillance Network(CHINET)revealed that the KP isolation rate from clinical respiratory specimens in China was the highest(18.1%)among all bacteria.[1]Both classical(cKP)and hypervirulent KP(hvKP)exert significant effects on the systemic inflammatory response,causing infection-related anemia and high mortality to host.The main gap in current research is that the specific virulence factors of KP that cause host infectious anemia have not been identified.展开更多
基金supported by Beijing Key Clinical Specialty Funding(No.010071)the Clinical Cohort Construction Program of Peking University Third Hospital(No.BYSYDL2019007)+1 种基金Clinical Key Project of Peking University Third Hospital(No.BYSYZD2022007)Peking University Outstanding Doctoral Student Innovation Funding(No.BMU2024BSS001).
文摘To the Editor:Klebsiella pneumoniae(KP)is a common opportunistic pathogen causing potentially life-threatening illness and organ failure.Surveillance data from the 2023 China Antimicrobial Surveillance Network(CHINET)revealed that the KP isolation rate from clinical respiratory specimens in China was the highest(18.1%)among all bacteria.[1]Both classical(cKP)and hypervirulent KP(hvKP)exert significant effects on the systemic inflammatory response,causing infection-related anemia and high mortality to host.The main gap in current research is that the specific virulence factors of KP that cause host infectious anemia have not been identified.
