Objective To assess the effectiveness of complementary food supplements with protein and multi-micronutrients on hemoglobin and anemia in infants and young children. Methods In 5 poor counties of Gansu, 984 children a...Objective To assess the effectiveness of complementary food supplements with protein and multi-micronutrients on hemoglobin and anemia in infants and young children. Methods In 5 poor counties of Gansu, 984 children aged 6-12 months were enrolled and divided into two groups. In addition to the usual home-made complementary food, all the children were fed one sachet of either Formula Ⅰ or Formula Ⅱ supplements each day. Protein and micronutrients were provided in Formula Ⅰ, while the same energy intake was secured in Formula Ⅱ as in Formula Ⅰ. A massive dose of vitamin A was supplemented to all the children every 6 months. Hemoglobin test was done at the same time. Results Prevalence of anemia was about 35% in both Formula Ⅰ and Formula Ⅱ group at baseline, and there were no differences in hemoglobin concentration between the two groups, During the 6-month and 12-month supplementation, hemoglobin of children in Formula Ⅰ group was higher than that in Formula Ⅱ group （P〈0.05）, and hemoglobin increase in Formula Ⅰ group was significantly higher than that in Formula Ⅱ group （P〈0.001）. After 6- and 12-mouth supplementation, the prevalence of anemia in Formula Ⅰ group dropped to 19.1% and 8.2% respectively, and it was 28.0% and 12.4% in Formula 2 group. The prevalence of anemia in Formula Ⅰ group was significantly lower than that in Formula Ⅱ group （P〈0.05）. After adjusting age and hemoglobin level at baseline, the hemoglobin increase at age of 24 months in formula 1 group was higher （10.7 g/L vs 7.9 g/L, P〈0.0001）. Conclusion Micronutrient fortified complementary food supplements, with large-dose vitamin A, is effective for children aged 6-12 months in terms of iron deficiency prevention.展开更多
Objective: to explore and analyze the effect and clinical curative effect of fructooligosaccharides on improving constipation in infants and young children. Methods: from December 2020 to December 2021, 70 infants and...Objective: to explore and analyze the effect and clinical curative effect of fructooligosaccharides on improving constipation in infants and young children. Methods: from December 2020 to December 2021, 70 infants and young children with constipation who received diagnosis and treatment in our hospital from December 2020 to December 2021 were selected as observation objects and included in this study. The control group and the observation group were divided into 35 children in each group. All the children in the control group were treated with conventional treatment, while the children in the observation group were treated with fructooligosaccharide combined with conventional treatment, and the therapeutic effects of the two groups were compared. Results: (1) After treatment, the clinical efficacy of the children in the observation group was better than that of the control group. The total effective rate of clinical treatment was 94.29%, which was higher than 82.86% of the control group, (P<0.05). (2) After treatment, the improvement time of the children in the observation group was shorter than that in the control group, such as difficulty in defecation, poor defecation, dry stool, and less frequent defecation, with statistical significance (P<0.05);(3) According to the clinical observation records, both groups had complications and disease recurrence, but the complication rate and recurrence rate of the observation group were 5.71% and 8.57%, which were significantly lower than the control groups 14.29% and 20.00%, (P<0.05) were statistically significant. Conclusion: fructooligosaccharides can play a significant role in improving constipation in infants and young children, help children quickly relieve the symptoms of defecation difficulty, improve treatment efficiency, shorten treatment time, and reduce the risk of complications. It is a safe and effective method of treatment.展开更多
[Objective]To evaluate the efficacy of adding multidisciplinary team(MDT)-led meridian-acupointmassage toconventional treatment forinfants with community-acquired pneumonia(CAP).[Methods]In this randomized trial,100 i...[Objective]To evaluate the efficacy of adding multidisciplinary team(MDT)-led meridian-acupointmassage toconventional treatment forinfants with community-acquired pneumonia(CAP).[Methods]In this randomized trial,100 infants with CAP were assigned to a control group(n=50)receiving conventional therapy or an intervention group(n=50)receiving conventional therapy plusMDT-led meridian-acupoint massage.Clinical efficacy,symptom resolution time,hospital stay,and family satisfaction were compared.[Results]Compared to the control group,the interventiongroup showed a significantly higher total effective rate(94.0% vs.78.0%),faster resolution of fever,cough,and pulmonary rales,a shorter hospital stay,and higher family satisfaction(96.0% vs.80.0%)(all P<0.05).[Conclusion]Adding MDT-led meridian-acupoint massage to conventional therapyimproves clinical outcomes,shortens recovery time,and increases family satisfaction for infants withCAP,demonstrating its strong potential for clinical application.展开更多
Based on the survey data of 4,739 infants and young children(IYC)under 3 years old,the study uses the propensity score matching(PSM)method to examine the role of family migration in infant and young child development(...Based on the survey data of 4,739 infants and young children(IYC)under 3 years old,the study uses the propensity score matching(PSM)method to examine the role of family migration in infant and young child development(IYCD).The study finds that the development of migrant IYC is significantly behind that of non-migrant IYC in the real-world situation.After controlling for confounders at the individual and family levels,there is no significant statistical difference in early development between migrant IYC and non-migrant IYC.Moreover,family migration does not play a significant role in IYCD in different subgroups after PSM.To protect the rights of migrant families and IYC in accessing public services,the Chinese government should build a social security policy system for migrant families and ensure starting point fairness for migrant IYC.展开更多
Objective: to explore the effect of early intervention nursing measures to promote the development of infant growth and development in children. Methods: in order to comprehensively improve the early growth and develo...Objective: to explore the effect of early intervention nursing measures to promote the development of infant growth and development in children. Methods: in order to comprehensively improve the early growth and development of children and implement the intervention nursing measures, 80 cases of infants who visited our department from July 2019 to July 2020 were selected and divided into the control group and the research group. The control group received routine early childhood care. On the basis of the control group, the research group adopted the child health care intervention nursing measures to give full play to the influence of the two groups in caring for the growth and development of children. Results: effective analysis of the physical conditions of infants in different groups temporarily after the 12-month intervention nursing intervention showed that their average height was (76.85±6.27)cm, and the data from the comprehensive analysis study group were significantly superior to those of the control group (73.02±1.93)cm. The data on the related clinical nursing intervention effects of infants in the two groups were statistically significant (P < 0.05). In terms of NET score, by exploring the growth and development of infants in two groups, the score data of the research group at 6 months, 9 months and 12 months were significantly better than the application related data of the control group. The difference between the two groups was statistically significant (P < 0.05). Conclusion: the effective combination of early implementation of scientific management interventions in two groups of infants significantly promotes the growth and development of children in all aspects. Through comparative analysis, the growth and development as well as the intelligence development of infants measured by the growth and development status of infants in the research group are significantly better than those in the control group, which is worthy of clinical promotion.展开更多
Aim:To explore the clinical characteristics of reversible respiratory chain deficiency in infants and young children.Methods:A retrospective analysis was conducted on the clinical data of a newborn with recurrent resp...Aim:To explore the clinical characteristics of reversible respiratory chain deficiency in infants and young children.Methods:A retrospective analysis was conducted on the clinical data of a newborn with recurrent respiratory distress and elevated lactate levels,and relevant literature was reviewed.The patient,male,22 days old,had difficulty breathing,no weight gain,and symptoms such as shortness of breath and cyanosis after birth,which lasted for 68 days.There was no history of birth asphyxia rescue;Treatment with antibiotics,respiratory support,diuresis,acid correction,multiple vitamins,and levocarnitine did not improve symptoms;Gradual worsening of breathing difficulties accompanied by feeding difficulties and slow weight gain;Multiple rechecks of blood gas analysis indicate an increase in lactate levels.The laboratory results showed that the child in this case had obvious clinical manifestations of MD.Genetic examination showed MT-TE gene mutation,and the mother was a carrier of MT-TE gene mutation.Conclusion:In the face of recurrent respiratory distress accompanied by elevated lactate levels in newborns,when clinical manifestations of unexplained lactate levels,feeding difficulties,poor aspiration,reduced spontaneous activity,and low muscle tone occur,the possibility of mitochondrial disease should be considered,and genetic testing should be actively improved to clarify the diagnosis.This type of disease is different from other types of mitochondrial diseases.After active and effective treatment,the prognosis is good.The key is early diagnosis,reasonable treatment,timely development of reasonable treatment plans,reduction of complications,and improvement of the final prognosis of the child.展开更多
Objective:To explore and analyze the clinical value of echocardiography screening and dynamic observation for ductus arteriosus closure in newborns.Methods:The study was conducted from August 2022 to December 2023.500...Objective:To explore and analyze the clinical value of echocardiography screening and dynamic observation for ductus arteriosus closure in newborns.Methods:The study was conducted from August 2022 to December 2023.500 newborns who were admitted to our hospital were selected as research subjects for this study(Kunming Tongren Hospital).All subjects underwent echocardiography to determine the severity of patent ductus arteriosus(PDA).The inner diameter of the pulmonary artery was measured,and the pulmonary artery pressure was estimated through tricuspid regurgitation.If the patient had high pulmonary artery pressure,elective closure surgery was performed.Results:Among the 500 subjects,448 cases of ductus arteriosus closure and 52 cases of PDA were detected by echocardiography,including 23 cases of simple PDA,15 cases with patent foramen ovale,11 cases with atrial septal defect,1 case with muscular ventricular septal defect,1 case with tricuspid valve prolapse,and 1 case with tricuspid valve chordae tendineae rupture.After symptomatic treatment and intervention,their echocardiogram results were reviewed and no abnormalities were found.All measurement results of children with PDA combined with pulmonary hypertension were better than before treatment(P<0.05).Conclusion:Echocardiography is a fast,accurate,and reliable non-invasive imaging examination technology.It can significantly improve congenital heart disease detection rate in infants and young children.Early intervention based on the examination results can dramatically improve the quality of life of infants and young children with PDA.展开更多
Background： Although human parainfluenza virus （HPIV） has been determined as an important viral cause of acute respiratory infections （ARIs） in infants and young children, data on long-term investigation are stil...Background： Although human parainfluenza virus （HPIV） has been determined as an important viral cause of acute respiratory infections （ARIs） in infants and young children, data on long-term investigation are still lacking to disclose the infection pattern of HPIV in China. Methods： Nasopharyngeal aspirates were collected from 25,773 hospitalized pediatric patients with ARIs from January 2004 through December 2012 for respiratory virus screen by direct immuno-fluorescence assay. Results： Out of these specimens, 1675 （6.50%, 1675/25,773） showed HPIV positive, including 261 （1.01%, 261/25,773） for HPIVI, 28 （0.11%, 28/25,773） for HPIV2, and 1388 （5.39%, 1388/25373） for HPIV3, 2 of the samples were positive for both HPIV1 and HPIV3, and 36 were co-detected with other viruses. The positive rates of HPIVs were higher in those younger than 3 years old. HPIV3 was detected from all age groups, predominantly from patients under 3 years of age, and the highest frequency was found in those 6 months to 1-year old （352/4077, 8.63%）. HPlV3 was the dominant type in each of the years detected between May and July. HPIV1 showed a peak in every odd year, mainly in August or September. HPIV was detected most frequently from patients with upper respiratory infection （12.49%, 157/1257）, followed by bronchitis （ 11.13%, 176/2479）, asthma （9.31%, 43/462）, bronchiolitis （5.91%, 150/2536）, pneumonia （6.06%, 1034/17,068）, and those with underlying diseases （1.0%, 15/1506）. HPIV3 is the dominant type in these six disease groups referred above, especially in the asthma group. Conclusions： HPIV is one of the important viral causes of ARIs in infants and young children in Beijing based on the data from the hospitalized children covering a 9-year term. HPIV3 is the predominant type in all these years and in most of the disease groups. HPIVs with different types show different seasonality.展开更多
Natural disasters, war, civil unrest and other catastrophes continue to disrupt, and often seriously endanger, the lives of millions of people around the world. Whatever their cause, emergencies pose a particularly gr...Natural disasters, war, civil unrest and other catastrophes continue to disrupt, and often seriously endanger, the lives of millions of people around the world. Whatever their cause, emergencies pose a particularly grave threat to health, nutritional status and very survival of infants and young children. Fortunately, much of the disability and death typical among this age group in such circumstances can be averted-provided proper feeding and care can be ensured.展开更多
文摘Objective To assess the effectiveness of complementary food supplements with protein and multi-micronutrients on hemoglobin and anemia in infants and young children. Methods In 5 poor counties of Gansu, 984 children aged 6-12 months were enrolled and divided into two groups. In addition to the usual home-made complementary food, all the children were fed one sachet of either Formula Ⅰ or Formula Ⅱ supplements each day. Protein and micronutrients were provided in Formula Ⅰ, while the same energy intake was secured in Formula Ⅱ as in Formula Ⅰ. A massive dose of vitamin A was supplemented to all the children every 6 months. Hemoglobin test was done at the same time. Results Prevalence of anemia was about 35% in both Formula Ⅰ and Formula Ⅱ group at baseline, and there were no differences in hemoglobin concentration between the two groups, During the 6-month and 12-month supplementation, hemoglobin of children in Formula Ⅰ group was higher than that in Formula Ⅱ group （P〈0.05）, and hemoglobin increase in Formula Ⅰ group was significantly higher than that in Formula Ⅱ group （P〈0.001）. After 6- and 12-mouth supplementation, the prevalence of anemia in Formula Ⅰ group dropped to 19.1% and 8.2% respectively, and it was 28.0% and 12.4% in Formula 2 group. The prevalence of anemia in Formula Ⅰ group was significantly lower than that in Formula Ⅱ group （P〈0.05）. After adjusting age and hemoglobin level at baseline, the hemoglobin increase at age of 24 months in formula 1 group was higher （10.7 g/L vs 7.9 g/L, P〈0.0001）. Conclusion Micronutrient fortified complementary food supplements, with large-dose vitamin A, is effective for children aged 6-12 months in terms of iron deficiency prevention.
文摘Objective: to explore and analyze the effect and clinical curative effect of fructooligosaccharides on improving constipation in infants and young children. Methods: from December 2020 to December 2021, 70 infants and young children with constipation who received diagnosis and treatment in our hospital from December 2020 to December 2021 were selected as observation objects and included in this study. The control group and the observation group were divided into 35 children in each group. All the children in the control group were treated with conventional treatment, while the children in the observation group were treated with fructooligosaccharide combined with conventional treatment, and the therapeutic effects of the two groups were compared. Results: (1) After treatment, the clinical efficacy of the children in the observation group was better than that of the control group. The total effective rate of clinical treatment was 94.29%, which was higher than 82.86% of the control group, (P<0.05). (2) After treatment, the improvement time of the children in the observation group was shorter than that in the control group, such as difficulty in defecation, poor defecation, dry stool, and less frequent defecation, with statistical significance (P<0.05);(3) According to the clinical observation records, both groups had complications and disease recurrence, but the complication rate and recurrence rate of the observation group were 5.71% and 8.57%, which were significantly lower than the control groups 14.29% and 20.00%, (P<0.05) were statistically significant. Conclusion: fructooligosaccharides can play a significant role in improving constipation in infants and young children, help children quickly relieve the symptoms of defecation difficulty, improve treatment efficiency, shorten treatment time, and reduce the risk of complications. It is a safe and effective method of treatment.
基金Selffunded Scientific Research Project of Guangxi Zhuang Autonomous Region Administrationof Traditional Chinese Medicine(GXZYL20220605).
文摘[Objective]To evaluate the efficacy of adding multidisciplinary team(MDT)-led meridian-acupointmassage toconventional treatment forinfants with community-acquired pneumonia(CAP).[Methods]In this randomized trial,100 infants with CAP were assigned to a control group(n=50)receiving conventional therapy or an intervention group(n=50)receiving conventional therapy plusMDT-led meridian-acupoint massage.Clinical efficacy,symptom resolution time,hospital stay,and family satisfaction were compared.[Results]Compared to the control group,the interventiongroup showed a significantly higher total effective rate(94.0% vs.78.0%),faster resolution of fever,cough,and pulmonary rales,a shorter hospital stay,and higher family satisfaction(96.0% vs.80.0%)(all P<0.05).[Conclusion]Adding MDT-led meridian-acupoint massage to conventional therapyimproves clinical outcomes,shortens recovery time,and increases family satisfaction for infants withCAP,demonstrating its strong potential for clinical application.
基金funded by the National Natural Science Foundation of China(No.62177010)the Excellence Enhancement Program of the First-Class Education Discipline Project(No.YLXKPY-XSDW202209).
文摘Based on the survey data of 4,739 infants and young children(IYC)under 3 years old,the study uses the propensity score matching(PSM)method to examine the role of family migration in infant and young child development(IYCD).The study finds that the development of migrant IYC is significantly behind that of non-migrant IYC in the real-world situation.After controlling for confounders at the individual and family levels,there is no significant statistical difference in early development between migrant IYC and non-migrant IYC.Moreover,family migration does not play a significant role in IYCD in different subgroups after PSM.To protect the rights of migrant families and IYC in accessing public services,the Chinese government should build a social security policy system for migrant families and ensure starting point fairness for migrant IYC.
文摘Objective: to explore the effect of early intervention nursing measures to promote the development of infant growth and development in children. Methods: in order to comprehensively improve the early growth and development of children and implement the intervention nursing measures, 80 cases of infants who visited our department from July 2019 to July 2020 were selected and divided into the control group and the research group. The control group received routine early childhood care. On the basis of the control group, the research group adopted the child health care intervention nursing measures to give full play to the influence of the two groups in caring for the growth and development of children. Results: effective analysis of the physical conditions of infants in different groups temporarily after the 12-month intervention nursing intervention showed that their average height was (76.85±6.27)cm, and the data from the comprehensive analysis study group were significantly superior to those of the control group (73.02±1.93)cm. The data on the related clinical nursing intervention effects of infants in the two groups were statistically significant (P < 0.05). In terms of NET score, by exploring the growth and development of infants in two groups, the score data of the research group at 6 months, 9 months and 12 months were significantly better than the application related data of the control group. The difference between the two groups was statistically significant (P < 0.05). Conclusion: the effective combination of early implementation of scientific management interventions in two groups of infants significantly promotes the growth and development of children in all aspects. Through comparative analysis, the growth and development as well as the intelligence development of infants measured by the growth and development status of infants in the research group are significantly better than those in the control group, which is worthy of clinical promotion.
文摘Aim:To explore the clinical characteristics of reversible respiratory chain deficiency in infants and young children.Methods:A retrospective analysis was conducted on the clinical data of a newborn with recurrent respiratory distress and elevated lactate levels,and relevant literature was reviewed.The patient,male,22 days old,had difficulty breathing,no weight gain,and symptoms such as shortness of breath and cyanosis after birth,which lasted for 68 days.There was no history of birth asphyxia rescue;Treatment with antibiotics,respiratory support,diuresis,acid correction,multiple vitamins,and levocarnitine did not improve symptoms;Gradual worsening of breathing difficulties accompanied by feeding difficulties and slow weight gain;Multiple rechecks of blood gas analysis indicate an increase in lactate levels.The laboratory results showed that the child in this case had obvious clinical manifestations of MD.Genetic examination showed MT-TE gene mutation,and the mother was a carrier of MT-TE gene mutation.Conclusion:In the face of recurrent respiratory distress accompanied by elevated lactate levels in newborns,when clinical manifestations of unexplained lactate levels,feeding difficulties,poor aspiration,reduced spontaneous activity,and low muscle tone occur,the possibility of mitochondrial disease should be considered,and genetic testing should be actively improved to clarify the diagnosis.This type of disease is different from other types of mitochondrial diseases.After active and effective treatment,the prognosis is good.The key is early diagnosis,reasonable treatment,timely development of reasonable treatment plans,reduction of complications,and improvement of the final prognosis of the child.
文摘Objective:To explore and analyze the clinical value of echocardiography screening and dynamic observation for ductus arteriosus closure in newborns.Methods:The study was conducted from August 2022 to December 2023.500 newborns who were admitted to our hospital were selected as research subjects for this study(Kunming Tongren Hospital).All subjects underwent echocardiography to determine the severity of patent ductus arteriosus(PDA).The inner diameter of the pulmonary artery was measured,and the pulmonary artery pressure was estimated through tricuspid regurgitation.If the patient had high pulmonary artery pressure,elective closure surgery was performed.Results:Among the 500 subjects,448 cases of ductus arteriosus closure and 52 cases of PDA were detected by echocardiography,including 23 cases of simple PDA,15 cases with patent foramen ovale,11 cases with atrial septal defect,1 case with muscular ventricular septal defect,1 case with tricuspid valve prolapse,and 1 case with tricuspid valve chordae tendineae rupture.After symptomatic treatment and intervention,their echocardiogram results were reviewed and no abnormalities were found.All measurement results of children with PDA combined with pulmonary hypertension were better than before treatment(P<0.05).Conclusion:Echocardiography is a fast,accurate,and reliable non-invasive imaging examination technology.It can significantly improve congenital heart disease detection rate in infants and young children.Early intervention based on the examination results can dramatically improve the quality of life of infants and young children with PDA.
文摘Background： Although human parainfluenza virus （HPIV） has been determined as an important viral cause of acute respiratory infections （ARIs） in infants and young children, data on long-term investigation are still lacking to disclose the infection pattern of HPIV in China. Methods： Nasopharyngeal aspirates were collected from 25,773 hospitalized pediatric patients with ARIs from January 2004 through December 2012 for respiratory virus screen by direct immuno-fluorescence assay. Results： Out of these specimens, 1675 （6.50%, 1675/25,773） showed HPIV positive, including 261 （1.01%, 261/25,773） for HPIVI, 28 （0.11%, 28/25,773） for HPIV2, and 1388 （5.39%, 1388/25373） for HPIV3, 2 of the samples were positive for both HPIV1 and HPIV3, and 36 were co-detected with other viruses. The positive rates of HPIVs were higher in those younger than 3 years old. HPIV3 was detected from all age groups, predominantly from patients under 3 years of age, and the highest frequency was found in those 6 months to 1-year old （352/4077, 8.63%）. HPlV3 was the dominant type in each of the years detected between May and July. HPIV1 showed a peak in every odd year, mainly in August or September. HPIV was detected most frequently from patients with upper respiratory infection （12.49%, 157/1257）, followed by bronchitis （ 11.13%, 176/2479）, asthma （9.31%, 43/462）, bronchiolitis （5.91%, 150/2536）, pneumonia （6.06%, 1034/17,068）, and those with underlying diseases （1.0%, 15/1506）. HPIV3 is the dominant type in these six disease groups referred above, especially in the asthma group. Conclusions： HPIV is one of the important viral causes of ARIs in infants and young children in Beijing based on the data from the hospitalized children covering a 9-year term. HPIV3 is the predominant type in all these years and in most of the disease groups. HPIVs with different types show different seasonality.
文摘Natural disasters, war, civil unrest and other catastrophes continue to disrupt, and often seriously endanger, the lives of millions of people around the world. Whatever their cause, emergencies pose a particularly grave threat to health, nutritional status and very survival of infants and young children. Fortunately, much of the disability and death typical among this age group in such circumstances can be averted-provided proper feeding and care can be ensured.
