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A Quantitative Analysis of China’s Pharmacovigilance Policy Based on the PMC Index Model
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作者 Yao Tingzhen Wang Shuling 《Asian Journal of Social Pharmacy》 2025年第4期387-401,共15页
Objective To study the current situation of China’s pharmacovigilance system,and to provide some suggestions for the improvement of related policies.Methods A policy modeling consistency(PMC)index model of pharmacovi... Objective To study the current situation of China’s pharmacovigilance system,and to provide some suggestions for the improvement of related policies.Methods A policy modeling consistency(PMC)index model of pharmacovigilance policy was constructed to quantitatively assess the samples of policies combining text mining.Then,the PMC surface was established to obtain the visualization results of China’s pharmacovigilance policy samples,and their shortcomings were clearly analyzed by comparison.Results and Conclusion Forty-one percent of China’s pharmacovigilance policies were rated as excellent,54%as acceptable,and the overall evaluation was acceptable.But there is still some room for improvement.On the whole,there are problems of insufficient policy synergy,lack of policy incentives and constraints,and incomplete coverage of policy functions.It is recommended that China’s pharmacovigilance policy system should be optimized by strengthening policy coordination,increasing policy incentives and constraints,and guiding multi-subjects to participate in coordination.These findings and recommendations can provide operational ideas for the system of China’s pharmacovigilance policy. 展开更多
关键词 PHARMACOVIGILANCE PMC index model policy evaluation adverse drug reaction
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Importance of Weighting for Multi-Variable Habitat Suitability Index Model: A Case Study of Winter- Spring Cohort of Ommastrephes bartramii in the Northwestern Pacific Ocean 被引量:13
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作者 GONG Caixia CHEN Xinjun +1 位作者 GAO Feng CHEN Yong 《Journal of Ocean University of China》 SCIE CAS 2012年第2期241-248,共8页
Weighting values for different habitat variables used in multi-factor habitat suitability index (HSI) modeling reflect the relative influences of different variables on distribution of fish species. Using the winter-s... Weighting values for different habitat variables used in multi-factor habitat suitability index (HSI) modeling reflect the relative influences of different variables on distribution of fish species. Using the winter-spring cohort of neon flying squid (Ommastrephes bartramii) in the Northwestern Pacific Ocean as an example, we evaluated the impact of different weighting schemes on the HSI models based on sea surface temperature, gradient of sea surface temperature and sea surface height. We compared differences in predicted fishing effort and HSI values resulting from different weighting. The weighting for different habitat variables could greatly influence HSI modeling and should be carefully done based on their relative importance in influencing the resource spatial distribution. Weighting in a multi-factor HSI model should be further studied and optimization methods should be developed to improve forecasting squid spatial distributions. 展开更多
关键词 weighting multi-factors habitat suitability index model Ommastrephes bartramii Northwestern Pacific Ocean
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ASYMPTOTIC PROPERTIES OF ESTIMATORS IN PARTIALLY LINEAR SINGLE-INDEX MODEL FOR LONGITUDINAL DATA 被引量:3
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作者 田萍 杨林 薛留根 《Acta Mathematica Scientia》 SCIE CSCD 2010年第3期677-687,共11页
In this article, a partially linear single-index model /or longitudinal data is investigated. The generalized penalized spline least squares estimates of the unknown parameters are suggested. All parameters can be est... In this article, a partially linear single-index model /or longitudinal data is investigated. The generalized penalized spline least squares estimates of the unknown parameters are suggested. All parameters can be estimated simultaneously by the proposed method while the feature of longitudinal data is considered. The existence, strong consistency and asymptotic normality of the estimators are proved under suitable conditions. A simulation study is conducted to investigate the finite sample performance of the proposed method. Our approach can also be used to study the pure single-index model for longitudinal data. 展开更多
关键词 Longitudinal data partially linear single-index model penalized spline strong consistency asymptotic normality
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Prediction of Mechanical Properties of Hot Rolled Strip by Using Semi-Parametric Single-Index Model 被引量:3
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作者 ZHAO Yong-hong WENG Yang +2 位作者 PENG Ning-qi TANG Guang-bo LIU Zheng-dong 《Journal of Iron and Steel Research International》 SCIE EI CAS CSCD 2013年第7期9-15,共7页
A semi-parametric single-index model based approach was proposed for prediction of mechanical properties of hot rolled strip. Based on industrial production data, a semi-parametric single-index model was developed by ... A semi-parametric single-index model based approach was proposed for prediction of mechanical properties of hot rolled strip. Based on industrial production data, a semi-parametric single-index model was developed by choo-sing the appropriate kernel function and window width to predict the yield strength, tensile strength and elongation. When data samples are limited, compared with regression method and neural network method, the prediction results show that the semi-parametric single-index model based method is more adaptive and the prediction performance is superior to those by both regression and neural network methods. 展开更多
关键词 hot strip rolling mechanical property prediction regression analysis neural network~ semi-parametricsingle-index model
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An analysis of single-index model with monotonic link function 被引量:1
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作者 ZHU Li-ping YANG Xiao-yan +1 位作者 YU Zhou LIU Xiang-rong 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2008年第1期107-112,共6页
The single-index model with monotonic link function is investigated. Firstly, it is showed that the link function h(.) can be viewed by a graphic method. That is, the plot with the fitted response y on the horizonta... The single-index model with monotonic link function is investigated. Firstly, it is showed that the link function h(.) can be viewed by a graphic method. That is, the plot with the fitted response y on the horizontal axis and the observed y on the vertical axis can be used to visualize the link function. It is pointed out that this graphic approach is also applicable even when the link function is not monotonic. Note that many existing nonparametric smoothers can also be used to assess h(.). Therefore, the I-spline approximation of the link function via maximizing the covariance function with a penalty function is investigated in the present work. The consistency of the criterion is constructed. A small simulation is carried out to evidence the efficiency of the approach proposed in the paper. 展开更多
关键词 dimension reduction graphic regression I-spline MONOTONICITY single-index model.
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Comparing of Aviation Network Structure of Mid-south,Northwest and Southwest of China Based on Hierarchical Index Model 被引量:1
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作者 Cheng Xiangjun Yang Fang Xie Li 《Journal of Traffic and Transportation Engineering》 2020年第1期14-19,共6页
In order to compare the aviation network of mid-south,northwest and southwest of China to reveal the structure similarity and difference for providing quantitative evidence to construct regional aviation network and i... In order to compare the aviation network of mid-south,northwest and southwest of China to reveal the structure similarity and difference for providing quantitative evidence to construct regional aviation network and improve its structure,hierarchical index model of regional aviation network was established through dividing the aviation network into layers to research its structure characters.Data matrixes were defined to record the basic state of regional aviation network.Index matrixes were constructed to describe the quantitative features of regional aviation network.On the basis of these indexes,several structure indexes of all layers of aviation network were calculated to show the structure features of aviation network,such as ratio of passenger volume within the region with across the region,share rate of passenger volume among layers,ratio of average number of airline for each airport,ratio of average passenger volume for each airline and ratio of airline rate.According to the statistical data,similar structure of share rate of passenger volume among layers and average passenger volume for each airline in their regional aviation network was found after calculating.But on the side of ratio of passenger volume within the region with across the region,ratio of average number of airlines for each airport and ratio of airline rate were different. 展开更多
关键词 Regional aviation network comparing of structure hierarchical index model index matrix structure index
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Statistical Diagnostic for Varying-Coefficient Single-Index Models Based on Empirical Likelihood Method 被引量:1
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作者 王淑玲 邓小洪 廖大庆 《Journal of Donghua University(English Edition)》 EI CAS 2014年第4期493-496,共4页
Varying-coefficient single-index model( VCSIM) avoids the so-called "curse of dimensionality " and is flexible enough to include several important statistical models. This paper considers statistical diagnos... Varying-coefficient single-index model( VCSIM) avoids the so-called "curse of dimensionality " and is flexible enough to include several important statistical models. This paper considers statistical diagnosis for VCSIM. First,the parametric estimation equation is established based on empirical likelihood. Then,some diagnosis statistics are defined. At last, an example is given to illustrate all the results. 展开更多
关键词 varying-coefficient single-index model(VCSIM) empirical likelihood OUTLIERS influence analysis
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Variable Selection of Partially Linear Single-index Models 被引量:1
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作者 L U Yi-qiang HU Bin 《Chinese Quarterly Journal of Mathematics》 CSCD 2014年第3期392-399,共8页
In this article, we study the variable selection of partially linear single-index model(PLSIM). Based on the minimized average variance estimation, the variable selection of PLSIM is done by minimizing average varianc... In this article, we study the variable selection of partially linear single-index model(PLSIM). Based on the minimized average variance estimation, the variable selection of PLSIM is done by minimizing average variance with adaptive l1 penalty. Implementation algorithm is given. Under some regular conditions, we demonstrate the oracle properties of aLASSO procedure for PLSIM. Simulations are used to investigate the effectiveness of the proposed method for variable selection of PLSIM. 展开更多
关键词 variable selection adaptive LASSO minimized average variance estimation(MAVE) partially linear single-index model
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HABITAT SUITABILITY INDEX MODELS: GREY HERON NESTING IN ZHALONG NATIONAL NATURE RESERVE 被引量:1
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作者 孙洪志 高中信 王丹 《Journal of Northeast Forestry University》 SCIE CAS CSCD 1995年第2期61-64,共4页
Grey heron (Ardea cimerca) is one kind of the great birds which are often seen in the northeast marsh area of P.R.China, and there are many grey herons to reproduce in Zhalong Nature Reserve from March to August annua... Grey heron (Ardea cimerca) is one kind of the great birds which are often seen in the northeast marsh area of P.R.China, and there are many grey herons to reproduce in Zhalong Nature Reserve from March to August annually. In this paper, through the inveingation of the grey herons nesting habitat and according to the water depth, vegetation type, cover density and plan heigh of the nesting place, the grey heron’s nesting habitat suitability index medes are established. The main model is s=(s1xs2xs3xs4)1/4,where s1 is the water depth suitability index, s2 is the vegetation type suitability index, s3 is the cover density index, sa is the plant height suitability index. These models provide a kind of reliable method for evaluating the habitat quality of the grey heron’s nesting. 展开更多
关键词 GREY HERON NESTING HABITAT index model
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The efficiencies and their changes of China's resources-based cities employing DEA and Malmquist Index Models 被引量:21
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作者 Sun Wei Li Yang +1 位作者 Wang Dai Fan Jie 《Journal of Geographical Sciences》 SCIE CSCD 2012年第3期509-520,共12页
Employing DEA model and Malmquist productivity index, this paper probes into the urban efficiencies of 24 typical resources-based cities in China and their changes from 2000 to 2008. The research finds that the overal... Employing DEA model and Malmquist productivity index, this paper probes into the urban efficiencies of 24 typical resources-based cities in China and their changes from 2000 to 2008. The research finds that the overall efficiencies of the resources-based cities are just at a general level, and only a few of them reach the optimal level. The scale efficiency is the major determining factor of the achievement of overall efficiency, the effect of which, nevertheless, is reducing. From the perspective of classification characteristics, the resources-based cities in northeastern region have been in the front rank in terms of overall efficiency, pure technical efficiency and scale efficiency. There is a certain positive correlation between urban population scale and urban efficiency. The analysis of urban efficiency changes shows that the changes in overall efficiency of resources-based cities from 2000 to 2008 had a weak improving tendency. Both the technical change index and productivity change index decreased, indicating that the urban efficiency did not improve during this period, and the tendency of technical recession and productivity decline was obvious. In terms of the classification of urban efficiency changes, the urban overall efficiency improved in each of the four regions from 2000 to 2008, among which western region witnessed the greatest increase. Cities with different resource types have improved their urban overall efficiencies except steel-based cities. The urban overall efficiency increased in resources-based cities of different scales, with greater improvement in small and medium-sized cities than in big cities. 展开更多
关键词 resources-based cities DEA model Malmquist productivity index efficiency
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Finite Mixture of Heteroscedastic Single-Index Models
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作者 Peng Zeng 《Open Journal of Statistics》 2012年第1期12-20,共9页
In many applications a heterogeneous population consists of several subpopulations. When each subpopulation can be adequately modeled by a heteroscedastic single-index model, the whole population is characterized by a... In many applications a heterogeneous population consists of several subpopulations. When each subpopulation can be adequately modeled by a heteroscedastic single-index model, the whole population is characterized by a finite mixture of heteroscedastic single-index models. In this article, we propose an estimation algorithm for fitting this model, and discuss the implementation in detail. Simulation studies are used to demonstrate the performance of the algorithm, and a real example is used to illustrate the application of the model. 展开更多
关键词 EM Algorithm FINITE MIXTURE model HETEROGENEITY HETEROSCEDASTICITY Local Linear SMOOTHING Single-index model
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On the Robust Nonparametric Regression Estimate in the Single Functional Index Model
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作者 Billal Bentata Said Attaoui Elias Ould-Saïd 《Communications in Mathematics and Statistics》 2025年第6期1533-1565,共33页
In this work,we construct and study a family of robust nonparametric estimators for a regression function based on kernel methods.The data are functional,independent and identically distributed,and are linked to a sin... In this work,we construct and study a family of robust nonparametric estimators for a regression function based on kernel methods.The data are functional,independent and identically distributed,and are linked to a single-index model.Under general conditions,we establish the pointwise and uniform almost complete convergence,as well as the asymptotic normality of the estimator.We explicitly derive the asymptotic variance and,as a result,provide confidence bands for the theoretical parameter.A simulation study is conducted to illustrate the proposed methodology. 展开更多
关键词 Asymptotic normality Functional data Functional Hilbert space Kernel estimate Nonparametric model Robust regression Simulation study Single functional index model Uniform almost complete convergence
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Tests for nonparametric parts on partially linear single index models 被引量:5
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作者 Ri-quan ZHANG Department of Statistics, East China Normal University, Shanghai 200062, China Department of Mathematics, Shanxi Datong University, Datong 037009, China 《Science China Mathematics》 SCIE 2007年第3期439-449,共11页
Tests for nonparametric parts on partially linear single index models are considered in this paper. Based on the estimates obtained by the local linear method, the generalized likelihood ratio tests for the models are... Tests for nonparametric parts on partially linear single index models are considered in this paper. Based on the estimates obtained by the local linear method, the generalized likelihood ratio tests for the models are established. Under the null hypotheses the normalized tests follow asymptotically the χ2-distribution with the scale constants and the degrees of freedom being independent of the nuisance parameters, which is called the Wilks phenomenon. A simulated example is used to evaluate the performances of the testing procedures empirically. 展开更多
关键词 local linear method partially linear single index models generalized likelihood ratio test Wilks phenomenon χ 2-distribution 62G10 62G20
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Estimator of a change point in single index models 被引量:5
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作者 JIN BaiSuo DONG CuiLing +1 位作者 TAN ChangChun MIAO BaiQi 《Science China Mathematics》 SCIE 2014年第8期1701-1712,共12页
This paper considers the problem of change point in single index models.In order to obtain asymptotically valid confidence intervals for the estimation of the change point,the convergence rate and asymptotic distribut... This paper considers the problem of change point in single index models.In order to obtain asymptotically valid confidence intervals for the estimation of the change point,the convergence rate and asymptotic distribution of the change point estimate is studied.Some simulation results are presented which show that the numerical performance of our estimator is satisfactory. 展开更多
关键词 single index model change point convergence rate asymptotic distribution
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Inference of change-point in single index models 被引量:3
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作者 CAO GuanQun WANG ZhanFeng +1 位作者 WU YaoHua ZHAO LinCheng 《Science China Mathematics》 SCIE 2008年第10期1855-1870,共16页
Single index models are widely used in medicine, econometrics and some other fields. In this paper, we consider the inference of a change point problem in single index models. Based on density-weighted average derivat... Single index models are widely used in medicine, econometrics and some other fields. In this paper, we consider the inference of a change point problem in single index models. Based on density-weighted average derivative estimation (ADE) method, we propose a statistic to test whether a change point exists or not. The null distribution of the test statistic is obtained using a permutation technique. The permuted statistic is rigorously shown to have the same distribution in the limiting sense under both null and alternative hypotheses. After the null hypothesis of no change point is rejected, an ADE-based estimate of the change point is proposed under assumption that the change point is unique. A simulation study confirms the theoretical results. 展开更多
关键词 change point single index models density weighted average derivatives U-STATISTIC Brownian bridges 62F05 62G05
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A Relative Error Estimation Approach for Multiplicative Single Index Model 被引量:2
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作者 WANG Zhanfeng CHEN Zimu WU Yaohua 《Journal of Systems Science & Complexity》 SCIE EI CSCD 2017年第5期1160-1172,共13页
As an alternative to absolute error methods, such as the least square and least absolute deviation estimations, a product relative error estimation is proposed for a multiplicative single index regression model. Regre... As an alternative to absolute error methods, such as the least square and least absolute deviation estimations, a product relative error estimation is proposed for a multiplicative single index regression model. Regression coefficients in the model are estimated via a two-stage procedure and their statistical properties such as consistency and normality are studied. Numerical studies including simulation and a body fat example show that the proposed method performs well. 展开更多
关键词 Asymptotic properties least product relative error relative errors single index model
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STGI:a spatio-temporal grid index model for marine big data 被引量:3
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作者 Tengteng Qu Lizhe Wang +6 位作者 Jian Yu Jining Yan Guilin Xu Meng Li Chengqi Cheng Kaihua Hou Bo Chen 《Big Earth Data》 EI 2020年第4期435-450,共16页
Marine big data are characterized by a large amount and complex structures,which bring great challenges to data management and retrieval.Based on the GeoSOT Grid Code and the composite index structure of the MongoDB d... Marine big data are characterized by a large amount and complex structures,which bring great challenges to data management and retrieval.Based on the GeoSOT Grid Code and the composite index structure of the MongoDB database,this paper proposes a spatio-temporal grid index model(STGI)for efficient optimized query of marine big data.A spatio-temporal secondary index is created on the spatial code and time code columns to build a composite index in the MongoDB database used for the storage of massive marine data.Multiple comparative experiments demonstrate that the retrieval efficiency adopting the STGI approach is increased by more than two to three times compared with other index models.Through theoretical analysis and experimental verification,the conclusion could be achieved that the STGI model is quite suitable for retrieving large-scale spatial data with low time frequency,such as marine big data. 展开更多
关键词 GeoSOT spatio-temporal grid index model marine big data MONGODB
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Statistical inference on parametric part for partially linear single-index model 被引量:5
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作者 ZHANG RiQuan HUANG ZhenSheng 《Science China Mathematics》 SCIE 2009年第10期2227-2242,共16页
Statistical inference on parametric part for the partially linear single-index model (PLSIM) is considered in this paper. A profile least-squares technique for estimating the parametric part is proposed and the asympt... Statistical inference on parametric part for the partially linear single-index model (PLSIM) is considered in this paper. A profile least-squares technique for estimating the parametric part is proposed and the asymptotic normality of the profile least-squares estimator is given. Based on the estimator, a generalized likelihood ratio (GLR) test is proposed to test whether parameters on linear part for the model is under a contain linear restricted condition. Under the null model, the proposed GLR statistic follows asymptotically the χ2-distribution with the scale constant and degree of freedom independent of the nuisance parameters, known as Wilks phenomenon. Both simulated and real data examples are used to illustrate our proposed methods. 展开更多
关键词 asymptotic normality generalized likelihood ratio local linear method partially linear single-index model profile least-squares technique wilks phenomenon 62G10 62G20
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Weighted estimation of single index models with right censored responses
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作者 WANG YanHua LI XiaYan +1 位作者 WANG QiHua HE ShuYuan 《Science China Mathematics》 SCIE 2011年第3期479-514,共36页
In this paper,the unknown link function,the direction parameter,and the heteroscedastic variance in single index models are estimated by the random weight method under the random censorship,respectively.The central li... In this paper,the unknown link function,the direction parameter,and the heteroscedastic variance in single index models are estimated by the random weight method under the random censorship,respectively.The central limit theory and the convergence rate of the law of the iterated logarithm for the estimator of the direction parameter are derived,respectively.The optimal convergence rates for the estimators of the link function and the heteroscedastic variance are obtained.Simulation results support the theoretical results of the paper. 展开更多
关键词 single index models random censorship central limit theorem law of the iterated logarithm weighted least squares unknown link function
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Empirical likelihood confidence regions of the parameters in a partially linear single-index model 被引量:13
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作者 XUE Liugen~1 & ZHU Lixing~2 1. College of Applied Sciences,Beijing University of Technology,Beijing 100022,China 2. Department of Mathematics,Hong Kong Baptist University,Hong Kong,China 《Science China Mathematics》 SCIE 2005年第10期1333-1348,共16页
In this paper, a partially linear single-index model is investigated, and three empirical log-likelihood ratio statistics for the unknown parameters in the model are suggested. It is proved that the proposed statistic... In this paper, a partially linear single-index model is investigated, and three empirical log-likelihood ratio statistics for the unknown parameters in the model are suggested. It is proved that the proposed statistics are asymptotically standard chi-square under some suitable conditions, and hence can be used to construct the confidence regions of the parameters. Our methods can also deal with the confidence region construction for the index in the pure single-index model. A simulation study indicates that, in terms of coverage probabilities and average areas of the confidence regions, the proposed methods perform better than the least-squares method. 展开更多
关键词 PARTIALLY LINEAR single-index model empirical likelihood CONFIDENCE region CHI-SQUARE distribution coverage probability.
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